Publications 2024

Høyland LE, VanLinden MR, Niere M, Strømland Ø, Sharma S, Dietze J, Tolås I, Lucena E, Bifulco E, Sverkeli LJ, Cimadamore-Werthein C, Ashrafi H, Haukanes KF, van der Hoeven B, Dölle C, Davidsen C, Pettersen IKN, Tronstad KJ, Mjøs SA, Hayat F, Makarov MV, Migaud ME, Heiland I, Ziegler M (2024)
Subcellular NAD⁺ pools are interconnected and buffered by mitochondrial NAD
Nat Metab, 6 (12), 2319-2337
DOI 10.1038/s42255-024-01174-w, PubMed 39702414

Publications 2023

Doutel D, Davidson B, Nitschke Pettersen IK, Torgunrud A (2023)
Molecular characteristics of low-grade serous carcinoma in effusions
Cytopathology, 34 (2), 99-105
DOI 10.1111/cyt.13207, PubMed 36609991

Publications 2021

Dyrstad SE, Lotsberg ML, Tan TZ, Pettersen IKN, Hjellbrekke S, Tusubira D, Engelsen AST, Daubon T, Mourier A, Thiery JP, Dahl O, Lorens JB, Tronstad KJ, Røsland GV (2021)
Blocking Aerobic Glycolysis by Targeting Pyruvate Dehydrogenase Kinase in Combination with EGFR TKI and Ionizing Radiation Increases Therapeutic Effect in Non-Small Cell Lung Cancer Cells
Cancers (Basel), 13 (5)
DOI 10.3390/cancers13050941, PubMed 33668151

Hoel F, Hoel A, Pettersen IK, Rekeland IG, Risa K, Alme K, Sørland K, Fosså A, Lien K, Herder I, Thürmer HL, Gotaas ME, Schäfer C, Berge RK, Sommerfelt K, Marti HP, Dahl O, Mella O, Fluge Ø, Tronstad KJ (2021)
A map of metabolic phenotypes in patients with myalgic encephalomyelitis/chronic fatigue syndrome
JCI Insight, 6 (16)
DOI 10.1172/jci.insight.149217, PubMed 34423789

Mostafavi S, Balafkan N, Pettersen IKN, Nido GS, Siller R, Tzoulis C, Sullivan GJ, Bindoff LA (2021)
Distinct Mitochondrial Remodeling During Mesoderm Differentiation in a Human-Based Stem Cell Model
Front Cell Dev Biol, 9, 744777
DOI 10.3389/fcell.2021.744777, PubMed 34722525

Publications 2019

Pettersen IKN, Tusubira D, Ashrafi H, Dyrstad SE, Hansen L, Liu XZ, Nilsson LIH, Løvsletten NG, Berge K, Wergedahl H, Bjørndal B, Fluge Ø, Bruland O, Rustan AC, Halberg N, Røsland GV, Berge RK, Tronstad KJ (2019)
Upregulated PDK4 expression is a sensitive marker of increased fatty acid oxidation
Mitochondrion, 49, 97-110
DOI 10.1016/j.mito.2019.07.009, PubMed 31351920

Røsland GV, Dyrstad SE, Tusubira D, Helwa R, Tan TZ, Lotsberg ML, Pettersen IKN, Berg A, Kindt C, Hoel F, Jacobsen K, Arason AJ, Engelsen AST, Ditzel HJ, Lønning PE, Krakstad C, Thiery JP, Lorens JB, Knappskog S, Tronstad KJ (2019)
Epithelial to mesenchymal transition (EMT) is associated with attenuation of succinate dehydrogenase (SDH) in breast cancer through reduced expression of SDHC
Cancer Metab, 7, 6
DOI 10.1186/s40170-019-0197-8, PubMed 31164982

Sivertsen Åsrud K, Pedersen L, Aesoy R, Muwonge H, Aasebø E, Nitschke Pettersen IK, Herfindal L, Dobie R, Jenkins S, Berge RK, Henderson NC, Selheim F, Døskeland SO, Bakke M (2019)
Mice depleted for Exchange Proteins Directly Activated by cAMP (Epac) exhibit irregular liver regeneration in response to partial hepatectomy
Sci Rep, 9 (1), 13789
DOI 10.1038/s41598-019-50219-8, PubMed 31551444

Publications 2016

Hodneland Nilsson LI, Nitschke Pettersen IK, Nikolaisen J, Micklem D, Avsnes Dale H, Vatne Røsland G, Lorens J, Tronstad KJ (2016)
Corrigendum: A new live-cell reporter strategy to simultaneously monitor mitochondrial biogenesis and morphology
Sci Rep, 6, 30527
DOI 10.1038/srep30527, PubMed 27541795

Mamaeva V, Niemi R, Beck M, Özliseli E, Desai D, Landor S, Gronroos T, Kronqvist P, Pettersen IK, McCormack E, Rosenholm JM, Linden M, Sahlgren C (2016)
Inhibiting Notch Activity in Breast Cancer Stem Cells by Glucose Functionalized Nanoparticles Carrying γ-secretase Inhibitors
Mol Ther, 24 (5), 926-36
DOI 10.1038/mt.2016.42, PubMed 26916284

Publications 2015

Hodneland Nilsson LI, Nitschke Pettersen IK, Nikolaisen J, Micklem D, Avsnes Dale H, Vatne Røsland G, Lorens J, Tronstad KJ (2015)
A new live-cell reporter strategy to simultaneously monitor mitochondrial biogenesis and morphology
Sci Rep, 5, 17217
DOI 10.1038/srep17217, PubMed 26596249

VanLinden MR, Dölle C, Pettersen IK, Kulikova VA, Niere M, Agrimi G, Dyrstad SE, Palmieri F, Nikiforov AA, Tronstad KJ, Ziegler M (2015)
Subcellular Distribution of NAD+ between Cytosol and Mitochondria Determines the Metabolic Profile of Human Cells
J Biol Chem, 290 (46), 27644-59
DOI 10.1074/jbc.M115.654129, PubMed 26432643

Publications 2014

Nikolaisen J, Nilsson LI, Pettersen IK, Willems PH, Lorens JB, Koopman WJ, Tronstad KJ (2014)
Automated quantification and integrative analysis of 2D and 3D mitochondrial shape and network properties
PLoS One, 9 (7), e101365
DOI 10.1371/journal.pone.0101365, PubMed 24988307

Tronstad KJ, Nooteboom M, Nilsson LI, Nikolaisen J, Sokolewicz M, Grefte S, Pettersen IK, Dyrstad S, Hoel F, Willems PH, Koopman WJ (2014)
Regulation and quantification of cellular mitochondrial morphology and content
Curr Pharm Des, 20 (35), 5634-52
DOI 10.2174/1381612820666140305230546, PubMed 24606803