Jørgen Vildershøj Bjørnholt

  • Associate professor; PhD

Associate Professor Institute of Clinical Medicine at the University of Oslo and Senior Consultant Department of Microbiology, Oslo University Hospital (Rikshospitalet).

Short background

  • MD University of Copenhagen 1991
  • PhD University of Oslo 2003
  • Specialist in Infectious Diseases and Medical Microbiology
  • Associate Professor Institute of Clinical Medicine Oslo University and senior consultant at department of microbiology Oslo University Hospital 2017
  • Group leader "Fungal and bacterial infections research group" Department of microbiology 2022

Publications 2024

Danielsen AS, Nygaard NJ, Børseth AW, Nilsen JV, Øvreness H, Raastad R, Borg MA, Kacelnik O, Bjørnholt JV (2024)
Patient perspectives on infection prevention and control in cancer care: a survey of knowledge and attitudes among persons with cancer and their next of kin
J Hosp Infect, 146, 21-30
DOI 10.1016/j.jhin.2024.01.012, PubMed 38311296

Fostervold A, Raffelsberger N, Hetland MAK, Bakksjø R, Bernhoff E, Samuelsen Ø, Sundsfjord A, Afset JE, Berntsen CF, Bævre-Jensen R, Ebbesen MH, Gammelsrud KW, Guleng AD, Handal N, Jakovljev A, Johal SK, Marvik Å, Natvik A, Sandnes RA, Tofteland S, Bjørnholt JV, Löhr IH, Assoc. on behalf of The Norwegian Study Group on Klebsiella pneumoniae (2024)
Risk of death in Klebsiella pneumoniae bloodstream infections is associated with specific phylogenetic lineages
J Infect, 88 (5), 106155
DOI 10.1016/j.jinf.2024.106155, PubMed 38574775

Oldereid TS, Jiang X, Øgaard J, Schrumpf E, Bjørnholt JV, Rasmussen H, Melum E (2024)
Microbial exposure during early life regulates development of bile duct inflammation
Scand J Gastroenterol, 59 (2), 192-201
DOI 10.1080/00365521.2023.2278423, PubMed 37997753

Publications 2023

Al Rubaye M, Janice J, Bjørnholt JV, Kacelnik O, Haldorsen BC, Nygaard RM, Hegstad J, Sundsfjord A, Hegstad K, The Norwegian Vre Study Group (2023)
The population structure of vancomycin-resistant and -susceptible Enterococcus faecium in a low-prevalence antimicrobial resistance setting is highly influenced by circulating global hospital-associated clones
Microb Genom, 9 (12)
DOI 10.1099/mgen.0.001160, PubMed 38112685

Al Rubaye M, Janice J, Bjørnholt JV, Löhr IH, Sundsfjord A, Hegstad K (2023)
The first vanE-type vancomycin resistant Enterococcus faecalis isolates in Norway - phenotypic and molecular characteristics
J Glob Antimicrob Resist, 36, 193-199
DOI 10.1016/j.jgar.2023.12.021, PubMed 38154751

Brendefur Corwin LM, Campbell P, Jakobsen K, Müller F, Lai X, Unemo M, Leegaard TM, Vildershøj Bjørnholt J, Olsen AO (2023)
Improvement in Neisseria gonorrhoeae culture rates by bedside inoculation and incubation at a clinic for sexually transmitted infections
Ann Clin Microbiol Antimicrob, 22 (1), 27
DOI 10.1186/s12941-023-00576-0, PubMed 37072830

Christensen I, Berild D, Bjørnholt JV, Jelsness-Jørgensen LP, Debes SM, Haug JB (2023)
The Role of Procalcitonin as an Antimicrobial Stewardship Tool in Patients Hospitalized with Seasonal Influenza
Antibiotics (Basel), 12 (3)
DOI 10.3390/antibiotics12030573, PubMed 36978440

Corwin LMB, Ingebretsen A, Campbell P, Alfsnes K, Müller F, Mauder N, Koomey M, Bjørnholt JV (2023)
Fourier transform infrared spectroscopy; can it be used as a rapid typing method of Neisseria gonorrhoeae?
J Microbiol Methods, 205, 106675
DOI 10.1016/j.mimet.2023.106675, PubMed 36681126

Danielsen AS, Elstrøm P, Eriksen-Volle HM, Hofvind S, Eyre DW, Kacelnik O, Bjørnholt JV (2023)
The epidemiology of multidrug-resistant organisms in persons diagnosed with cancer in Norway, 2008-2018: expanding surveillance using existing laboratory and register data
Eur J Clin Microbiol Infect Dis, 43 (1), 121-132
DOI 10.1007/s10096-023-04698-3, PubMed 37980302

Danielsen AS, Franconeri L, Page S, Myhre AE, Tornes RA, Kacelnik O, Bjørnholt JV (2023)
Clinical outcomes of antimicrobial resistance in cancer patients: a systematic review of multivariable models
BMC Infect Dis, 23 (1), 247
DOI 10.1186/s12879-023-08182-3, PubMed 37072711

Hegstad K, Pöntinen AK, Bjørnholt JV, Quist-Paulsen E, Sundsfjord A (2023)
The first tigecycline resistant Enterococcus faecium in Norway was related to tigecycline exposure
J Glob Antimicrob Resist, 36, 112-115
DOI 10.1016/j.jgar.2023.12.002, PubMed 38122982

Heim AVBT, Janice J, Bjørnholt JV, Lunestad BT, Hegstad K, Svanevik CS (2023)
Genomic insights into Enterococcus faecium isolates from marine bivalves highlight One Health concerns and healthcare linkages
Microb Genom, 9 (12)
DOI 10.1099/mgen.0.001154, PubMed 38085805

Oldereid TS, Jiang X, Nordhus KS, Ponzetta A, Bjørnholt JV, Björkström NK, Melum E, Rasmussen H (2023)
Role of bacteria and microbial metabolites in immune modulation during early life
Scand J Immunol, 99 (2), e13336
DOI 10.1111/sji.13336, PubMed 38441196

Publications 2022

Christensen I, Berild D, Jelsness-Jørgensen LP, Bjørnholt JV, Haug JB (2022)
[Tailored interventions result in better antimicrobial management in Norwegian hospitals]
Tidsskr Nor Laegeforen, 142 (5)
DOI 10.4045/tidsskr.22.0094, PubMed 35324115

Christensen I, Haug JB, Berild D, Bjørnholt JV, Skodvin B, Jelsness-Jørgensen LP (2022)
Factors Affecting Antibiotic Prescription among Hospital Physicians in a Low-Antimicrobial-Resistance Country: A Qualitative Study
Antibiotics (Basel), 11 (1)
DOI 10.3390/antibiotics11010098, PubMed 35052975

Fraz MSA, Dahle G, Skaug KM, Jarraud S, Frye S, Bjørnholt JV, Nordøy I (2022)
Case report: A prosthetic valve endocarditis caused by Legionella bozemanae in an immunocompetent patient
Front Med (Lausanne), 9, 1055465
DOI 10.3389/fmed.2022.1055465, PubMed 36405607

Publications 2021

Al Rubaye MTS, Janice J, Bjørnholt JV, Jakovljev A, Hultström ME, Sundsfjord A, Hegstad K (2021)
Novel genomic islands and a new vanD-subtype in the first sporadic VanD-type vancomycin resistant enterococci in Norway
PLoS One, 16 (7), e0255187
DOI 10.1371/journal.pone.0255187, PubMed 34297779

Falk RS, Mariampillai JE, Prestgaard EE, Heir T, Bodegård J, Robsahm TE, Grundvold I, Skretteberg PT, Engeseth K, Bjornholt JV, Stavem K, Liestøl K, Sandvik L, Thaulow E, Erikssen G, Kjeldsen SE, Gjesdal K, Erikssen JE (2021)
The Oslo Ischaemia Study: cohort profile
BMJ Open, 11 (10), e049111
DOI 10.1136/bmjopen-2021-049111, PubMed 34645662

Lossius AH, Sundnes O, Ingham AC, Edslev SM, Bjørnholt JV, Lilje B, Bradley M, Asad S, Haraldsen G, Skytt-Andersen P, Holm JØ, Berents TL (2021)
Shifts in the Skin Microbiota after UVB Treatment in Adult Atopic Dermatitis
Dermatology, 238 (1), 109-120
DOI 10.1159/000515236, PubMed 33887725

Ramstad SN, Brandal LT, Taxt AM, Wasteson Y, Bjørnholt JV, Naseer U (2021)
Prevalence of genotypic antimicrobial resistance in clinical Shiga toxin-producing Escherichia coli in Norway, 2018 to 2020
J Med Microbiol, 70 (12)
DOI 10.1099/jmm.0.001454, PubMed 34870582

Ramstad SN, Wasteson Y, Lindstedt BA, Taxt AM, Bjørnholt JV, Brandal LT, Bohlin J (2021)
Characterization of Shiga Toxin 2a Encoding Bacteriophages Isolated From High-Virulent O145:H25 Shiga Toxin-Producing Escherichia coli
Front Microbiol, 12, 728116
DOI 10.3389/fmicb.2021.728116, PubMed 34566932

Størdal EH, Solevåg AL, Bjørnholt JV, Rønnestad A, Stensvold HJ (2021)
Sepsis treatment options identified by 10-year study of microbial isolates and antibiotic susceptibility in a level-four neonatal intensive care unit
Acta Paediatr, 111 (3), 519-526
DOI 10.1111/apa.16189, PubMed 34787905

Publications 2020

Christensen I, Haug JB, Berild D, Bjørnholt JV, Jelsness-Jørgensen LP (2020)
Hospital physicians' experiences with procalcitonin - implications for antimicrobial stewardship; a qualitative study
BMC Infect Dis, 20 (1), 515
DOI 10.1186/s12879-020-05246-6, PubMed 32677903

Ramstad SN, Taxt AM, Naseer U, Wasteson Y, Bjørnholt JV, Brandal LT (2020)
Effects of antimicrobials on Shiga toxin production in high-virulent Shiga toxin-producing Escherichia coli
Microb Pathog, 152, 104636
DOI 10.1016/j.micpath.2020.104636, PubMed 33242644

Publications 2019

Berdal JE, Follin-Arbelet B, Bjørnholt JV (2019)
Experiences from multiplex PCR diagnostics of faeces in hospitalised patients: clinical significance of Enteropathogenic Escherichia coli (EPEC) and culture negative campylobacter
BMC Infect Dis, 19 (1), 630
DOI 10.1186/s12879-019-4271-1, PubMed 31315581

Di Ruscio F, Guzzetta G, Bjørnholt JV, Leegaard TM, Moen AEF, Merler S, Freiesleben de Blasio B (2019)
Quantifying the transmission dynamics of MRSA in the community and healthcare settings in a low-prevalence country
Proc Natl Acad Sci U S A, 116 (29), 14599-14605
DOI 10.1073/pnas.1900959116, PubMed 31262808

Publications 2018

Dahl C, Stigum H, Valeur J, Iszatt N, Lenters V, Peddada S, Bjørnholt JV, Midtvedt T, Mandal S, Eggesbø M (2018)
Preterm infants have distinct microbiomes not explained by mode of delivery, breastfeeding duration or antibiotic exposure
Int J Epidemiol, 47 (5), 1658-1669
DOI 10.1093/ije/dyy064, PubMed 29688458

Publications 2017

Di Ruscio F, Bjørnholt JV, Larssen KW, Leegaard TM, Moen AE, de Blasio BF (2017)
Epidemiology and spa-type diversity of meticillin-resistant Staphylococcus aureus in community and healthcare settings in Norway
J Hosp Infect, 100 (3), 316-321
DOI 10.1016/j.jhin.2017.12.019, PubMed 29288777

Di Ruscio F, Bjørnholt JV, Leegaard TM, Moen AEF, de Blasio BF (2017)
MRSA infections in Norway: A study of the temporal evolution, 2006-2015
PLoS One, 12 (6), e0179771
DOI 10.1371/journal.pone.0179771, PubMed 28640901

Johnsen BO, Handal N, Meisal R, Bjørnholt JV, Gaustad P, Leegaard TM (2017)
erm gene distribution among Norwegian Bacteroides isolates and evaluation of phenotypic tests to detect inducible clindamycin resistance in Bacteroides species
Anaerobe, 47, 226-232
DOI 10.1016/j.anaerobe.2017.06.004, PubMed 28602805

Samuelsen Ø, Overballe-Petersen S, Bjørnholt JV, Brisse S, Doumith M, Woodford N, Hopkins KL, Aasnæs B, Haldorsen B, Sundsfjord A, Norwegian Study Group on CPE (2017)
Molecular and epidemiological characterization of carbapenemase-producing Enterobacteriaceae in Norway, 2007 to 2014
PLoS One, 12 (11), e0187832
DOI 10.1371/journal.pone.0187832, PubMed 29141051

Publications 2016

Bjørnholt J, Kacelnik O, Eriksen HM (2016)
[Re: Cumulative summation in monitoring postoperative wound infections]
Tidsskr Nor Laegeforen, 136 (2), 105-6
DOI 10.4045/tidsskr.15.1366, PubMed 26813811

Blomfeldt A, Eskesen AN, Aamot HV, Leegaard TM, Bjørnholt JV (2016)
Population-based epidemiology of Staphylococcus aureus bloodstream infection: clonal complex 30 genotype is associated with mortality
Eur J Clin Microbiol Infect Dis, 35 (5), 803-13
DOI 10.1007/s10096-016-2601-4, PubMed 26873380

Blomfeldt A, Aamot HV, Eskesen AN, Monecke S, White RA, Leegaard TM, Bjørnholt JV (2016)
DNA microarray analysis of Staphylococcus aureus causing bloodstream infection: bacterial genes associated with mortality?
Eur J Clin Microbiol Infect Dis, 35 (8), 1285-95
DOI 10.1007/s10096-016-2663-3, PubMed 27177754

Grøntvedt CA, Elstrøm P, Stegger M, Skov RL, Skytt Andersen P, Larssen KW, Urdahl AM, Angen Ø, Larsen J, Åmdal S, Løtvedt SM, Sunde M, Bjørnholt JV (2016)
Methicillin-Resistant Staphylococcus aureus CC398 in Humans and Pigs in Norway: A "One Health" Perspective on Introduction and Transmission
Clin Infect Dis, 63 (11), 1431-1438
DOI 10.1093/cid/ciw552, PubMed 27516381

Mandal S, Godfrey KM, McDonald D, Treuren WV, Bjørnholt JV, Midtvedt T, Moen B, Rudi K, Knight R, Brantsæter AL, Peddada SD, Eggesbø M (2016)
Fat and vitamin intakes during pregnancy have stronger relations with a pro-inflammatory maternal microbiota than does carbohydrate intake
Microbiome, 4 (1), 55
DOI 10.1186/s40168-016-0200-3, PubMed 27756413

Publications 2014

Bentele H, Bergsaker MR, Hauge SH, Bjørnholt JV (2014)
Vaccination coverage for seasonal influenza among residents and health care workers in Norwegian nursing homes during the 2012/13 season, a cross-sectional study
BMC Public Health, 14, 434
DOI 10.1186/1471-2458-14-434, PubMed 24885662

Berdal JE, Haagensen R, Ranheim T, Bjørnholt JV (2014)
Nosocomial candidemia; risk factors and prognosis revisited; 11 years experience from a Norwegian secondary hospital
PLoS One, 9 (7), e103916
DOI 10.1371/journal.pone.0103916, PubMed 25079361

Skjeldestad FE, Bjørnholt JV, Gran JM, Erisken HM (2014)
The effect of antibiotic prophylaxis guidelines on surgical-site infections associated with cesarean delivery
Int J Gynaecol Obstet, 128 (2), 126-30
DOI 10.1016/j.ijgo.2014.08.018, PubMed 25456970

Publications 2013

White RA, Bjørnholt JV, Baird DD, Midtvedt T, Harris JR, Pagano M, Hide W, Rudi K, Moen B, Iszatt N, Peddada SD, Eggesbø M (2013)
Novel developmental analyses identify longitudinal patterns of early gut microbiota that affect infant growth
PLoS Comput Biol, 9 (5), e1003042
DOI 10.1371/journal.pcbi.1003042, PubMed 23671411

Publications 2010

Sandven P, Steinbakk M, Bjørnholt JV (2010)
Anaerob diagnostikk
In Eksterne kvalitetsvurderinger i bakteriologi, mykologi ogparasittologi, Nasjonalt folkehelseinstitutt, Divisjon for smittevern, Oslo, nr. 23, 2009, 75 s.
BIBSYS 101722788, ISBN 978-82-8082-422-6

Publications 2006

Berdal JE, Smith-Erichsen N, Bjørnholt JV, Blomfeldt A, Bukholm G (2006)
Does Pseudomonas aeruginosa colonization influence morbidity and mortality in the intensive care unit patient? Experience from an outbreak caused by contaminated oral swabs
Acta Anaesthesiol Scand, 50 (9), 1095-102
DOI 10.1111/j.1399-6576.2006.01044.x, PubMed 16987339

Publications 2005

Berdal JE, Skråmm I, Mowinckel P, Gulbrandsen P, Bjørnholt JV (2005)
Use of rifampicin and ciprofloxacin combination therapy after surgical debridement in the treatment of early manifestation prosthetic joint infections
Clin Microbiol Infect, 11 (10), 843-5
DOI 10.1111/j.1469-0691.2005.01230.x, PubMed 16153261

Bodegard J, Erikssen G, Bjørnholt JV, Gjesdal K, Liestøl K, Erikssen J (2005)
Reasons for terminating an exercise test provide independent prognostic information: 2014 apparently healthy men followed for 26 years
Eur Heart J, 26 (14), 1394-401
DOI 10.1093/eurheartj/ehi278, PubMed 15855193

Stavem K, Aaser E, Sandvik L, Bjørnholt JV, Erikssen G, Thaulow E, Erikssen J (2005)
Lung function, smoking and mortality in a 26-year follow-up of healthy middle-aged males
Eur Respir J, 25 (4), 618-25
DOI 10.1183/09031936.05.00008504, PubMed 15802334

Publications 2004

Bodegard J, Erikssen G, Bjornholt JV, Thelle D, Erikssen J (2004)
Possible angina detected by the WHO angina questionnaire in apparently healthy men with a normal exercise ECG: coronary heart disease or not? A 26 year follow up study
Heart, 90 (6), 627-32
DOI 10.1136/hrt.2003.012542, PubMed 15145862

Bodegard J, Erikssen G, Bjørnholt JV, Gjesdal K, Thelle D, Erikssen J (2004)
Symptom-limited exercise testing, ST depressions and long-term coronary heart disease mortality in apparently healthy middle-aged men
Eur J Cardiovasc Prev Rehabil, 11 (4), 320-7
DOI 10.1097/01.hjr.0000136460.57921.46, PubMed 15292766

Erikssen G, Bodegard J, Bjørnholt JV, Liestøl K, Thelle DS, Erikssen J (2004)
Exercise testing of healthy men in a new perspective: from diagnosis to prognosis
Eur Heart J, 25 (11), 978-86
DOI 10.1016/j.ehj.2004.04.009, PubMed 15172470

Yaqub S, Bjørnholt JV, Enger AE (2004)
[Tularemia from a cat bite]
Tidsskr Nor Laegeforen, 124 (24), 3197-8
PubMed 15608764

Yaqub S, Bjørnholt JV, Hellum KB, Steinbakk M, Enger AE (2004)
[Bite wound infections]
Tidsskr Nor Laegeforen, 124 (24), 3194-6
PubMed 15608763

Publications 2003

Bjørnholt JV, Erikssen G, Kjeldsen SE, Bodegård J, Thaulow E, Erikssen J (2003)
Fasting blood glucose is independently associated with resting and exercise blood pressures and development of elevated blood pressure
J Hypertens, 21 (7), 1383-9
DOI 10.1097/00004872-200307000-00029, PubMed 12817188

Publications 2002

Bodegard J, Erikssen G, Sandvik L, Kjeldsen SE, Bjørnholt J, Erikssen JE (2002)
Early versus late morning measurement of blood pressure in healthy men. A potential source of measurement bias?
Blood Press, 11 (6), 366-70
DOI 10.1080/080370502321095339, PubMed 12523680

Publications 2001

Bjørnholt JV, Erikssen G, Liestøl K, Jervell J, Erikssen J, Thaulow E (2001)
Prediction of Type 2 diabetes in healthy middle-aged men with special emphasis on glucose homeostasis. Results from 22.5 years' follow-up
Diabet Med, 18 (4), 261-7
DOI 10.1046/j.1464-5491.2001.00488.x, PubMed 11437855

Publications 2000

Bjørnholt JV, Erikssen G, Liestøl K, Jervell J, Thaulow E, Erikssen J (2000)
Type 2 diabetes and maternal family history: an impact beyond slow glucose removal rate and fasting hyperglycemia in low-risk individuals? Results from 22.5 years of follow-up of healthy nondiabetic men
Diabetes Care, 23 (9), 1255-9
DOI 10.2337/diacare.23.9.1255, PubMed 10977015

Erikssen G, Liestøl K, Bjørnholt JV, Stormorken H, Thaulow E, Erikssen J (2000)
Erythrocyte sedimentation rate: a possible marker of atherosclerosis and a strong predictor of coronary heart disease mortality
Eur Heart J, 21 (19), 1614-20
DOI 10.1053/euhj.2000.2148, PubMed 10988014

Erikssen G, Liestøl K, Bjørnholt JV, Thaulow E, Erikssen J (2000)
Hypothesis: the recent decline in coronary heart disease mortality--mainly a shift from fatal to non-fatal events?
Scand Cardiovasc J, 34 (5), 468-74
DOI 10.1080/140174300750064620, PubMed 11191936

Publications 1999

Bjørnholt JV, Erikssen G, Aaser E, Sandvik L, Nitter-Hauge S, Jervell J, Erikssen J, Thaulow E (1999)
Fasting blood glucose: an underestimated risk factor for cardiovascular death. Results from a 22-year follow-up of healthy nondiabetic men
Diabetes Care, 22 (1), 45-9
DOI 10.2337/diacare.22.1.45, PubMed 10333902

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