PubMed registered articles Jorrit M. Enserink
Publications by Jorrit M. Enserink
70 publications found
Publications 2024
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CD37 is a safe chimeric antigen receptor target to treat acute myeloid leukemia
Cell Rep Med, 5 (6), 101572
DOI 10.1016/j.xcrm.2024.101572, PubMed 38754420 -
Characterization of a selective, iron-chelating antifungal compound that disrupts fungal metabolism and synergizes with fluconazole
Microbiol Spectr, 12 (2), e0259423
DOI 10.1128/spectrum.02594-23, PubMed 38230926 -
Promising anti-proliferative indolic benzenesulfonamides alter mechanisms with sulfonamide nitrogen substituents
Eur J Med Chem, 275, 116617
DOI 10.1016/j.ejmech.2024.116617, PubMed 38959729 -
Using birth-death processes to infer tumor subpopulation structure from live-cell imaging drug screening data
PLoS Comput Biol, 20 (3), e1011888
DOI 10.1371/journal.pcbi.1011888, PubMed 38446830
Publications 2023
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CELLULAR, A Cell Autophagy Imaging Dataset
Sci Data, 10 (1), 806
DOI 10.1038/s41597-023-02687-x, PubMed 37973836 -
Clinical forecasting of acute myeloid leukemia using ex vivo drug-sensitivity profiling
Cell Rep Methods, 3 (12), 100654
DOI 10.1016/j.crmeth.2023.100654, PubMed 38065095 -
Standardized assays to monitor drug sensitivity in hematologic cancers
Cell Death Discov, 9 (1), 435
DOI 10.1038/s41420-023-01722-5, PubMed 38040674 -
Robust scoring of selective drug responses for patient-tailored therapy selection
Nat Protoc, 19 (1), 60-82
DOI 10.1038/s41596-023-00903-x, PubMed 37996540 -
screenwerk: a modular tool for the design and analysis of drug combination screens
Bioinformatics, 39 (1)
DOI 10.1093/bioinformatics/btac840, PubMed 36573326 -
The human leukemic oncogene MLL-AF4 promotes hyperplastic growth of hematopoietic tissues in Drosophila larvae
iScience, 26 (10), 107726
DOI 10.1016/j.isci.2023.107726, PubMed 37720104 -
Phenotypic deconvolution in heterogeneous cancer cell populations using drug-screening data
Cell Rep Methods, 3 (3), 100417
DOI 10.1016/j.crmeth.2023.100417, PubMed 37056380 -
Mitotic chromosome condensation resets chromatin to safeguard transcriptional homeostasis during interphase
Proc Natl Acad Sci U S A, 120 (4), e2210593120
DOI 10.1073/pnas.2210593120, PubMed 36656860 -
Early response evaluation by single cell signaling profiling in acute myeloid leukemia
Nat Commun, 14 (1), 115
DOI 10.1038/s41467-022-35624-4, PubMed 36611026 -
Author Correction: Early response evaluation by single cell signaling profiling in acute myeloid leukemia
Nat Commun, 14 (1), 1767
DOI 10.1038/s41467-023-37488-8, PubMed 36997540 -
Using birth-death processes to infer tumor subpopulation structure from live-cell imaging drug screening data
ArXiv
PubMed 37396610
Publications 2022
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The SUMO stress response in transcriptional regulation: Causal relationships or secondary bystander effects?
Bioessays, 44 (7), e2200065
DOI 10.1002/bies.202200065, PubMed 35655365 -
Cell Cycle-Dependent Transcription: The Cyclin Dependent Kinase Cdk1 Is a Direct Regulator of Basal Transcription Machineries
Int J Mol Sci, 23 (3)
DOI 10.3390/ijms23031293, PubMed 35163213 -
Analysis of the pheromone signaling pathway by RT-qPCR in the budding yeast Saccharomyces cerevisiae
STAR Protoc, 3 (1), 101210
DOI 10.1016/j.xpro.2022.101210, PubMed 35265859 -
Waves of sumoylation support transcription dynamics during adipocyte differentiation
Nucleic Acids Res, 50 (3), 1351-1369
DOI 10.1093/nar/gkac027, PubMed 35100417
Publications 2021
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Pharmacologic Control of CAR T Cells
Int J Mol Sci, 22 (9)
DOI 10.3390/ijms22094320, PubMed 33919245 -
Kel1 is a phosphorylation-regulated noise suppressor of the pheromone signaling pathway
Cell Rep, 37 (13), 110186
DOI 10.1016/j.celrep.2021.110186, PubMed 34965431 -
Discovery of novel candidates for anti-liposarcoma therapies by medium-scale high-throughput drug screening
PLoS One, 16 (3), e0248140
DOI 10.1371/journal.pone.0248140, PubMed 33690666 -
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
Autophagy, 17 (1), 1-382
DOI 10.1080/15548627.2020.1797280, PubMed 33634751 -
Mcl-1 and Bcl-xL levels predict responsiveness to dual MEK/Bcl-2 inhibition in B-cell malignancies
Mol Oncol, 16 (5), 1153-1170
DOI 10.1002/1878-0261.13153, PubMed 34861096 -
bayesynergy: flexible Bayesian modelling of synergistic interaction effects in in vitro drug combination experiments
Brief Bioinform, 22 (6)
DOI 10.1093/bib/bbab251, PubMed 34308471
Publications 2020
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Tyrosine kinase inhibitors and interferon-α increase tunneling nanotube (TNT) formation and cell adhesion in chronic myeloid leukemia (CML) cell lines
FASEB J, 34 (3), 3773-3791
DOI 10.1096/fj.201802061RR, PubMed 31945226 -
A cell competition-based small molecule screen identifies a novel compound that induces dual c-Myc depletion and p53 activation
J Biol Chem, 296, 100179
DOI 10.1074/jbc.RA120.015285, PubMed 33303632
Publications 2019
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Desumoylation of RNA polymerase III lies at the core of the Sumo stress response in yeast
J Biol Chem, 294 (49), 18784-18795
DOI 10.1074/jbc.RA119.009721, PubMed 31676685 -
5-hydroxymethylcytosine Marks Mammalian Origins Acting as a Barrier to Replication
Sci Rep, 9 (1), 11065
DOI 10.1038/s41598-019-47528-3, PubMed 31363131 -
GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells
Haematologica, 104 (5), e229
DOI 10.3324/haematol.2019.220533, PubMed 31040234
Publications 2018
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Cdk1 gates cell cycle-dependent tRNA synthesis by regulating RNA polymerase III activity
Nucleic Acids Res, 46 (22), 11698-11711
DOI 10.1093/nar/gky846, PubMed 30247619 -
Corrigendum: Cdk1 gates cell cycle-dependent tRNA synthesis by regulating RNA polymerase III activity
Nucleic Acids Res, 46 (22), 12188-12189
DOI 10.1093/nar/gky1102, PubMed 30395271 -
Centromeres License the Mitotic Condensation of Yeast Chromosome Arms
Cell, 175 (3), 780-795.e15
DOI 10.1016/j.cell.2018.09.012, PubMed 30318142 -
GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells
Haematologica, Online ahead of print (in press) (Retracted)
DOI 10.3324/haematol.2018.189399, PubMed 29748445
Publications 2017
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Regulation of tRNA synthesis by posttranslational modifications of RNA polymerase III subunits
Biochim Biophys Acta Gene Regul Mech, 1861 (4), 310-319
DOI 10.1016/j.bbagrm.2017.11.001, PubMed 29127063 -
TORC1-dependent sumoylation of Rpc82 promotes RNA polymerase III assembly and activity
Proc Natl Acad Sci U S A, 114 (5), 1039-1044
DOI 10.1073/pnas.1615093114, PubMed 28096404 -
Corrigendum: Sumoylation of Rap1 mediates the recruitment of TFIID to promote transcription of ribosomal protein genes
Genome Res, 27 (2), 334
DOI 10.1101/gr.218370.116, PubMed 28148563 -
Anabolic transcription: Secrets of the sumo diet
Cell Cycle, 16 (7), 593-594
DOI 10.1080/15384101.2017.1294945, PubMed 28278057 -
Regulation of Cellular Processes by SUMO: Understudied Topics
Adv Exp Med Biol, 963, 89-97
DOI 10.1007/978-3-319-50044-7_5, PubMed 28197907 -
Sumo during stress: When transcription takes a pause (comment on DOI.10.1002/bies.201600263)
Bioessays, 39 (6)
DOI 10.1002/bies.201700065, PubMed 28464310 -
Differentiation status of primary chronic myeloid leukemia cells affects sensitivity to BCR-ABL1 inhibitors
Oncotarget, 8 (14), 22606-22615
DOI 10.18632/oncotarget.15146, PubMed 28186983 -
Mapping the Synthetic Dosage Lethality Network of CDK1/CDC28
G3 (Bethesda), 7 (6), 1753-1766
DOI 10.1534/g3.117.042317, PubMed 28428242 -
TORC1 Inhibits GSK3-Mediated Elo2 Phosphorylation to Regulate Very Long Chain Fatty Acid Synthesis and Autophagy
Cell Rep, 18 (8), 2073-2074
DOI 10.1016/j.celrep.2017.02.020, PubMed 28228270
Publications 2016
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Autophagy, 12 (1), 1-222
DOI 10.1080/15548627.2015.1100356, PubMed 26799652
Publications 2015
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SUMO-regulated transcription: challenging the dogma
Bioessays, 37 (10), 1095-105
DOI 10.1002/bies.201500065, PubMed 26354225 -
Sumoylation of Rap1 mediates the recruitment of TFIID to promote transcription of ribosomal protein genes
Genome Res, 25 (6), 897-906
DOI 10.1101/gr.185793.114, PubMed 25800674 -
Sumo and the cellular stress response
Cell Div, 10, 4
DOI 10.1186/s13008-015-0010-1, PubMed 26101541
Publications 2014
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Identification and characterization of a novel evolutionarily conserved lysine-specific methyltransferase targeting eukaryotic translation elongation factor 2 (eEF2)
J Biol Chem, 289 (44), 30499-30510
DOI 10.1074/jbc.M114.601658, PubMed 25231979 -
Metabolic pathways further increase the complexity of cell size control in budding yeast
Microb Cell, 1 (9), 276-278
DOI 10.15698/mic2014.09.167, PubMed 28362005
Publications 2013
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TORC1 inhibits GSK3-mediated Elo2 phosphorylation to regulate very long chain fatty acid synthesis and autophagy
Cell Rep, 5 (4), 1036-46
DOI 10.1016/j.celrep.2013.10.024, PubMed 24239358
Publications 2012
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Cdc28 kinase activity regulates the basal transcription machinery at a subset of genes
Proc Natl Acad Sci U S A, 109 (26), 10450-5
DOI 10.1073/pnas.1200067109, PubMed 22689984 -
The cell cycle rallies the transcription cycle: Cdc28/Cdk1 is a cell cycle-regulated transcriptional CDK
Transcription, 4 (1), 3-6
DOI 10.4161/trns.22456, PubMed 23131667 -
Chemical genetics: budding yeast as a platform for drug discovery and mapping of genetic pathways
Molecules, 17 (8), 9258-73
DOI 10.3390/molecules17089258, PubMed 22858845 -
What makes the engine hum: Rad6, a cell cycle supercharger
Cell Cycle, 11 (2), 249-52
DOI 10.4161/cc.11.2.19023, PubMed 22214660 -
Global mapping of protein phosphorylation events identifies Ste20, Sch9 and the cell-cycle regulatory kinases Cdc28/Pho85 as mediators of fatty acid starvation responses in Saccharomyces cerevisiae
Mol Biosyst, 8 (3), 796-803
DOI 10.1039/c2mb05356j, PubMed 22218487
Publications 2011
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A chemical-genetic screen to unravel the genetic network of CDC28/CDK1 links ubiquitin and Rad6-Bre1 to cell cycle progression
Proc Natl Acad Sci U S A, 108 (46), 18748-53
DOI 10.1073/pnas.1115885108, PubMed 22042866
Publications 2010
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An overview of Cdk1-controlled targets and processes
Cell Div, 5, 11
DOI 10.1186/1747-1028-5-11, PubMed 20465793
Publications 2009
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Cdc28/Cdk1 positively and negatively affects genome stability in S. cerevisiae
J Cell Biol, 185 (3), 423-37
DOI 10.1083/jcb.200811083, PubMed 19398760 -
The Saccharomyces cerevisiae Rad6 postreplication repair and Siz1/Srs2 homologous recombination-inhibiting pathways process DNA damage that arises in asf1 mutants
Mol Cell Biol, 29 (19), 5226-37
DOI 10.1128/MCB.00894-09, PubMed 19635810
Publications 2006
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The cyclic AMP-Epac1-Rap1 pathway is dissociated from regulation of effector functions in monocytes but acquires immunoregulatory function in mature macrophages
J Immunol, 176 (12), 7361-70
DOI 10.4049/jimmunol.176.12.7361, PubMed 16751380 -
Checkpoint proteins control morphogenetic events during DNA replication stress in Saccharomyces cerevisiae
J Cell Biol, 175 (5), 729-41
DOI 10.1083/jcb.200605080, PubMed 17130284 -
An FHA domain-mediated protein interaction network of Rad53 reveals its role in polarized cell growth
J Cell Biol, 175 (5), 743-53
DOI 10.1083/jcb.200605081, PubMed 17130285
Publications 2004
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The cAMP-Epac-Rap1 pathway regulates cell spreading and cell adhesion to laminin-5 through the alpha3beta1 integrin but not the alpha6beta4 integrin
J Biol Chem, 279 (43), 44889-96
DOI 10.1074/jbc.M404599200, PubMed 15302884 -
The epidermal growth factor-like growth factor amphiregulin is strongly induced by the adenosine 3',5'-monophosphate pathway in various cell types
Endocrinology, 145 (11), 5177-84
DOI 10.1210/en.2004-0232, PubMed 15284208 -
Knockdown of C-terminal Src kinase by siRNA-mediated RNA interference augments T cell receptor signaling in mature T cells
Eur J Immunol, 34 (8), 2191-9
DOI 10.1002/eji.200425036, PubMed 15259016
Publications 2003
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The role of Rap1 in integrin-mediated cell adhesion
Biochem Soc Trans, 31 (Pt 1), 83-6
DOI 10.1042/bst0310083, PubMed 12546659 -
Cyclic AMP induces integrin-mediated cell adhesion through Epac and Rap1 upon stimulation of the beta 2-adrenergic receptor
J Cell Biol, 160 (4), 487-93
DOI 10.1083/jcb.200209105, PubMed 12578910
Publications 2002
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A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK
Nat Cell Biol, 4 (11), 901-6
DOI 10.1038/ncb874, PubMed 12402047 -
Large-scale chromatin organization and the localization of proteins involved in gene expression in human cells
J Histochem Cytochem, 50 (10), 1303-12
DOI 10.1177/002215540205001003, PubMed 12364563
Publications 2000
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Molecular characterization of celtix-1, a bromodomain protein interacting with the transcription factor interferon regulatory factor 2
J Cell Physiol, 185 (2), 269-79
DOI 10.1002/1097-4652(200011)185:2<269::AID-JCP12>3.0.CO;2-L, PubMed 11025449