Preoperative Data Models for Personalized Survival Treatment Analysis for Patients with Colorectal Liver Metastases, Funded byHelse Sør-Øst.
Synthetic data for clinical validation of Artificial Intelligence powered tools in healthcare, DNV
The Oslo CoMet-study (Oslo randomized laparoscopic vs open liver resection for colorectal liver metastasis – study). In addition to the evaluation of surgical and oncological results,several translational studies are performed, such as bio banking of tumor tissue, studies on the inflammatory response, health economy evaluation and pain/quality of life studies. Funding: The South-Eastern Regional Norway Health Authority
Oslo New CoMet: RCT comparing surgical treatment with local ablation for colorectal liver metastasis. Funding: The South-Eastern Regional Norway Health Authority.
Multicentre studies on laparoscopic liver surgery
Multicentre studies on pancreatic surgery
Research on pancreatic cancer: Examining the role of Laparoscopic Distal Pancreatectomy (LDP) in the treatment of Pancreatic Cancer: From a Consensus Study to Randomized Controlled Trials. The main aim is to assess the oncologic outcomes of Laparoscopic Distal Pancreatectomy in patients with Pancreatic Distal Adeno- Carcinoma, determine the prognostic factors and provide justified recommendations for its use. Funding: Post Doc project called “Irreversible electroporation - a novel ablation modality in unresectable hepato-pancrea- to-biliary cancer” funded from the Division ofEmergencies and Critical Care, Oslo UniversityHospital.
Research on imaging of liver tumors (CT, MRI, PET-CT) conducted with other research groups at the Intervention Centre and the Oslo University Hospital
In a joint project, a method for automatic segmentation of liver anatomy including tumors is developed. The final goal is to create an interactive map for liver surgeons that will greatly ease both planning and the actual surgery.
Research on D3 resection of colon cancer
Research on reasons to onset of type 1 diabetes: The DiVid study
Research on biomaterials in implants together with the University of Gothenburg.
The research group is also involved in many major projects e.g. HiPerNav, (EU project), NorMit, MetAction and BigMed.
Drejian S, Akhavi MS, Grzyb K, Kazaryan A, Fretland ÅA, Edwin B, Aghayan D(2026) Histopathologic growth patterns as prognostic factor for survival in patients with colorectal liver metastases Radiol Oncol, 60(1), 114-123 DOI 10.2478/raon-2026-0002, PubMed 41686533
Hansen IS, Aghayan DL, Pelanis E, Røsok BI, Brudvik KW, Yaqub S, Lassen K, Bjørk I, Brabrand K, Edwin B, Syversveen T, Fretland ÅA(2026) Long-Term Oncological Outcomes After Laparoscopic Resection and Thermal Ablation of Colorectal Liver Metastases Within a Parenchyma-Sparing Strategy Ann Surg Oncol(in press) DOI 10.1245/s10434-026-19621-1, PubMed 41979846
Laimer G, Johnston EW, Overduin CG, Paolucci I, Ahmed M, Arellano RS, Beermann M, Beyer LP, Breen DJ, Burgmans MC, Calandri M, Chern MC, Crocetti L, van Dam RM, Denys A, Edwin B, Filippiadis D, Fong Y, Fotiadis N, Freedman J, Fretland ÅA, Gimenez M, Garcia RG, Grasso RF, Helmberger TKet al.(2026) International multisociety Delphi consensus for liver tumour thermal ablation: procedural and practice standards Lancet Oncol, 27(5), e259-e270 DOI 10.1016/S1470-2045(26)00114-2, PubMed 42061383