Anne Flem Jacobsen
- Senior consultant; MD, PhD
- +47 23 01 57 62
Publications 2024
Clinical examination for identifying low-risk pregnancies suitable for expectant management beyond 40-41 gestational weeks: maternal and fetal outcomes
Arch Gynecol Obstet (in press)
DOI 10.1007/s00404-024-07869-5, PubMed 39681758
Publications 2023
Neonatal outcomes associated with time from a high fetal blood lactate concentration to operative delivery
Acta Obstet Gynecol Scand, 102 (8), 1106-1114
DOI 10.1111/aogs.14597, PubMed 37287317
Trends in Term Intrapartum Stillbirth in Norway
JAMA Netw Open, 6 (9), e2334830
DOI 10.1001/jamanetworkopen.2023.34830, PubMed 37755831
Publications 2022
Intermediate-dose versus low-dose low-molecular-weight heparin in pregnant and post-partum women with a history of venous thromboembolism (Highlow study): an open-label, multicentre, randomised, controlled trial
Lancet, 400 (10365), 1777-1787
DOI 10.1016/S0140-6736(22)02128-6, PubMed 36354038
Onset of labor and use of analgesia in women using thromboprophylaxis with 2 doses of low-molecular-weight heparin: insights from the Highlow study
J Thromb Haemost, 21 (1), 57-67
DOI 10.1016/j.jtha.2022.11.004, PubMed 36695396
Group B Streptococcus colonization at delivery is associated with maternal peripartum infection
PLoS One, 17 (4), e0264309
DOI 10.1371/journal.pone.0264309, PubMed 35363775
Can a population study assess the impact of fetal monitoring technology?
Acta Obstet Gynecol Scand, 101 (12), 1458-1459
DOI 10.1111/aogs.14426, PubMed 35879814
Intrapartum pudendal nerve block analgesia and childbirth experience in primiparous women with vaginal birth: A cohort study
Birth, 50 (1), 182-191
DOI 10.1111/birt.12697, PubMed 36529699
Publications 2021
Audit of Early and Late Maternal Deaths in Georgia: Potential for Improving Substandard Obstetric Care
Int J Womens Health, 13, 205-219
DOI 10.2147/IJWH.S288763, PubMed 33628061
Treatment of Homozygous Type II Antithrombin Heparin-Binding Site Deficiency in Pregnancy
Case Rep Obstet Gynecol, 2021, 4393821
DOI 10.1155/2021/4393821, PubMed 34513101
Prior Thromboembolic Disease and Assisted Reproductive Therapy
Semin Reprod Med, 39 (5-06), 180-185
DOI 10.1055/s-0041-1732375, PubMed 34261142
Prospective assessment of vacuum deliveries from midpelvic station in a tertiary care university hospital: Frequency, failure rates, labor characteristics and maternal and neonatal complications
PLoS One, 16 (11), e0259926
DOI 10.1371/journal.pone.0259926, PubMed 34784382
Intrapartum pudendal nerve block analgesia and risk of postpartum urinary retention: a cohort study
Int Urogynecol J, 32 (9), 2383-2391
DOI 10.1007/s00192-021-04768-0, PubMed 33860813
Publications 2020
[Routine urine culture in pregnancy – it needs to stop]
Tidsskr Nor Laegeforen, 140 (17)
DOI 10.4045/tidsskr.20.0838, PubMed 33231398
Routine urine culture in pregnant women - stop it
Tidsskr. Nor. Laegeforen., 140 (17), 1735-1736
Maternal Mortality in Georgia: Incidence, Causes and Level of Underreporting: A National Reproductive Age Mortality Study 2014
Int J Womens Health, 12, 277-286
DOI 10.2147/IJWH.S227349, PubMed 32308502
Adverse perinatal outcomes in 665,244 term and post-term deliveries-a Norwegian population-based study
Eur J Obstet Gynecol Reprod Biol, 247, 212-218
DOI 10.1016/j.ejogrb.2020.02.028, PubMed 32146227
Induction of labor and nulliparity: A nationwide clinical practice pilot evaluation
Acta Obstet Gynecol Scand, 99 (12), 1700-1709
DOI 10.1111/aogs.13948, PubMed 32609877
The provision of epidural analgesia during labor according to maternal birthplace: a Norwegian register study
BMC Pregnancy Childbirth, 20 (1), 321
DOI 10.1186/s12884-020-03021-8, PubMed 32456615
Publications 2019
Knowledge of gestational diabetes mellitus at first consultation in a multi-ethnic pregnant population in the Oslo region, Norway - a cross-sectional study
Ethn Health, 27 (1), 209-222
DOI 10.1080/13557858.2019.1655530, PubMed 31416352
Effect of the Pregnant+ smartphone application in women with gestational diabetes mellitus: a randomised controlled trial in Norway
BMJ Open, 9 (11), e030884
DOI 10.1136/bmjopen-2019-030884, PubMed 31719080
Elevated Complement C3 and C4 Levels are Associated with Postnatal Pregnancy-Related Venous Thrombosis
Thromb Haemost, 119 (9), 1481-1488
DOI 10.1055/s-0039-1692426, PubMed 31254974
Structured clinical examinations in labor: rekindling the craft of obstetrics
J Matern Fetal Neonatal Med, 34 (12), 1963-1969
DOI 10.1080/14767058.2019.1651283, PubMed 31422727
Publications 2018
Genome-wide analysis of genetic determinants of circulating factor VII-activating protease (FSAP) activity
J Thromb Haemost, 16 (10), 2024-2034
DOI 10.1111/jth.14258, PubMed 30070759
The structure and utility of the placental pathology report
APMIS, 126 (7), 638-646
DOI 10.1111/apm.12842, PubMed 30129133
Publications 2017
Smartphone application for women with gestational diabetes mellitus: a study protocol for a multicentre randomised controlled trial
BMJ Open, 7 (3), e013117
DOI 10.1136/bmjopen-2016-013117, PubMed 28348183
Risk factors for severe postpartum hemorrhage: a case-control study
BMC Pregnancy Childbirth, 17 (1), 17
DOI 10.1186/s12884-016-1217-0, PubMed 28068990
Publications 2016
Women's values and preferences and health state valuations for thromboprophylaxis during pregnancy: A cross-sectional interview
Thromb Res, 140, 22-9
DOI 10.1016/j.thromres.2015.12.015, PubMed 27500301
Low-molecular-weight heparin to prevent recurrent venous thromboembolism in pregnancy: Rationale and design of the Highlow study, a randomised trial of two doses
Thromb Res, 144, 62-8
DOI 10.1016/j.thromres.2016.06.001, PubMed 27289488
Antiphospholipid Antibodies are Associated with Low Levels of Complement C3 and C4 in Patients with Systemic Lupus Erythematosus
Scand J Immunol, 84 (2), 95-9
DOI 10.1111/sji.12445, PubMed 27135178
Why did the authors perform a meta-analysis of studies with primary endpoints they consider clinically unimportant?
Acta Obstet Gynecol Scand, 95 (5), 606-7
DOI 10.1111/aogs.12876, PubMed 26878842
Medication use and drug-related problems among women at maternity wards-a cross-sectional study from two Norwegian hospitals
Eur J Clin Pharmacol, 72 (7), 849-57
DOI 10.1007/s00228-016-2042-0, PubMed 27023461
Determinants of acquired activated protein C resistance and D-dimer in breast cancer
Thromb Res, 145, 78-83
DOI 10.1016/j.thromres.2016.08.003, PubMed 27505249
Publications 2015
Maternal Colonization with Group B Streptococcus Is Associated with an Increased Rate of Infants Transferred to the Neonatal Intensive Care Unit
Neonatology, 108 (3), 157-63
DOI 10.1159/000434716, PubMed 26182960
Genetic variations in the annexin A5 gene and the risk of pregnancy-related venous thrombosis
J Thromb Haemost, 13 (3), 409-13
DOI 10.1111/jth.12817, PubMed 25495894
The role of inflammation in post-thrombotic syndrome after pregnancy-related deep vein thrombosis: A population-based, cross-sectional study
Thromb Res, 138, 16-21
DOI 10.1016/j.thromres.2015.12.014, PubMed 26826503
Publications 2014
Comparison of PCR and serotyping of Group B Streptococcus in pregnant women: the Oslo GBS-study
J Microbiol Methods, 108, 31-5
DOI 10.1016/j.mimet.2014.11.001, PubMed 25447890
[Anticoagulation for venous thrombosis in pregnancy]
Tidsskr Nor Laegeforen, 134 (9), 926
DOI 10.4045/tidsskr.13.1605, PubMed 24828717
Perforation of the Pregnant Uterus during Laparoscopy for Suspected Internal Herniation after Gastric Bypass
Case Rep Obstet Gynecol, 2014, 720181
DOI 10.1155/2014/720181, PubMed 25548693
Forskningshåndboken: fra ide til publikasjon
(Carlsen KCL, Staff AC, eds.), Oslo University Hospital, Oslo, 6, 156
PublikaID 222, ISBN 978-82-473-0027-5
Increased coagulation activity and genetic polymorphisms in the F5, F10 and EPCR genes are associated with breast cancer: a case-control study
BMC Cancer, 14, 845
DOI 10.1186/1471-2407-14-845, PubMed 25407022
Maternal deaths in Norway 2005-2009
Tidsskr Nor Laegeforen, 134 (8), 836-9
DOI 10.4045/tidsskr.13.0203, PubMed 24780982
Publications 2013
Classification of stillbirths and risk factors by cause of death--a case-control study
Acta Obstet Gynecol Scand, 92 (3), 325-33
DOI 10.1111/aogs.12044, PubMed 23157574
Long-term mortality and incidence of cancer after pregnancy-related venous thrombosis: results of a population-based cohort study
Thromb Res, 131 (6), 497-501
DOI 10.1016/j.thromres.2013.04.035, PubMed 23726964
Publications 2012
Differential haemostatic risk factors for pregnancy-related deep-vein thrombosis and pulmonary embolism: a population-based case-control study
Thromb Haemost, 108 (6), 1165-71
DOI 10.1160/TH12-05-0350, PubMed 23015030
Candidate gene polymorphisms and the risk for pregnancy-related venous thrombosis
Br J Haematol, 157 (6), 753-61
DOI 10.1111/j.1365-2141.2012.09121.x, PubMed 22533697
Venous thromboembolism associated with pregnancy and hormonal therapy
Best Pract Res Clin Haematol, 25 (3), 319-32
DOI 10.1016/j.beha.2012.07.006, PubMed 22959548
Prevalence and predictors for post-thrombotic syndrome 3 to 16 years after pregnancy-related venous thrombosis: a population-based, cross-sectional, case-control study
J Thromb Haemost, 10 (5), 840-7
DOI 10.1111/j.1538-7836.2012.04690.x, PubMed 22452811
Long-term impact of pregnancy-related venous thrombosis on quality-of-life, general health and functioning: results of a cross-sectional, case-control study
BMJ Open, 2 (6)
DOI 10.1136/bmjopen-2012-002048, PubMed 23144263
Publications 2011
Resistance to activated protein C is a risk factor for pregnancy-related venous thrombosis in the absence of the F5 rs6025 (factor V Leiden) polymorphism
Br J Haematol, 154 (2), 241-7
DOI 10.1111/j.1365-2141.2011.08712.x, PubMed 21564075
Incidence and risk factors of fetal death in Norway: a case-control study
Acta Obstet Gynecol Scand, 90 (4), 390-7
DOI 10.1111/j.1600-0412.2011.01079.x, PubMed 21306337
The association of antiphospholipid antibodies with intrauterine fetal death: a case-control study
Thromb Res, 130 (1), 32-7
DOI 10.1016/j.thromres.2011.11.029, PubMed 22178574
The association of inherited thrombophilia and intrauterine fetal death: a case-control study
Blood Coagul Fibrinolysis, 22 (8), 651-6
DOI 10.1097/MBC.0b013e32834a614c, PubMed 22198364
Long-term quality of life after pregnancy-related deep vein thrombosis and the influence of socioeconomic factors and comorbidity
J Thromb Haemost, 9 (10), 1931-6
DOI 10.1111/j.1538-7836.2011.04468.x, PubMed 21848904
Publications 2010
The association of antiphospholipid antibodies with pregnancy-related first time venous thrombosis--a population-based case-control study
Thromb Res, 125 (5), e222-7
DOI 10.1016/j.thromres.2009.12.006, PubMed 20051285
Risk of venous thrombosis in pregnancy among carriers of the factor V Leiden and the prothrombin gene G20210A polymorphisms
J Thromb Haemost, 8 (11), 2443-9
DOI 10.1111/j.1538-7836.2010.04038.x, PubMed 20735725
Prophylaxis against prosthetic mitral valve thrombosis with unfractionated heparin administered by an elastometric infusion pump
Thromb Res, 126 (3), e232-4
DOI 10.1016/j.thromres.2010.05.005, PubMed 20553950
Publications 2008
Venous thrombosis in pregnancy and puerperium: epidemiology, aetiology, treatment and prophylaxis
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 678, 1 b. (flere pag.)
BIBSYS 082533393, ISBN 978-82-8072-909-5
Ante- and postnatal risk factors of venous thrombosis: a hospital-based case-control study
J Thromb Haemost, 6 (6), 905-12
DOI 10.1111/j.1538-7836.2008.02961.x, PubMed 18363820
Publications 2007
Incidence and risk patterns of venous thromboembolism in pregnancy and puerperium--a register-based case-control study
Am J Obstet Gynecol, 198 (2), 233.e1-7
DOI 10.1016/j.ajog.2007.08.041, PubMed 17997389
Publications 2005
Forskningshåndbok: fra idé til publikasjon
I samarbeid med Kompetansesenter for klinisk forskning, Haukeland universitetssykehus, Oslo (2. utg.), 123 s.
BIBSYS 060317140, ISBN 82-473-0017-6
Publications 2004
Deep vein thrombosis after elective cesarean section
Thromb Res, 113 (5), 283-8
DOI 10.1016/j.thromres.2004.03.008, PubMed 15183039
Publications 2003
Forskningshåndbok: fra idé til publikasjon
Vitenskapsrådet Ullevål universitetssykehus HF, Oslo, 89 s.
BIBSYS 040620689, ISBN 82-473-0017-6
Low molecular weight heparin (dalteparin) for the treatment of venous thromboembolism in pregnancy
BJOG, 110 (2), 139-44
PubMed 12618157
Early evaluation of bowel symptoms after primary repair of obstetric perineal rupture is misleading: an observational cohort study
Dis Colon Rectum, 46 (9), 1245-50
DOI 10.1007/s10350-004-6722-y, PubMed 12972970
Publications 2002
Is there any correlation between objective anal testing, rupture grade, and bowel symptoms after primary repair of obstetric anal sphincter rupture?: an observational cohort study
Dis Colon Rectum, 45 (10), 1325-31
DOI 10.1007/s10350-004-6419-2, PubMed 12394430
Publications 2001
Kvinneliv: hva alle kvinner bør vite om sin helse : en grunnleggendeveiledning om hvordan du holder frisk i puberteten ...
WEM3, Oslo, 318 s.
BIBSYS 010308245, ISBN 82-92013-05-9
Publications 2000
[Treatment of venous thromboembolism in pregnancy with low molecular weight heparin]
Tidsskr Nor Laegeforen, 120 (20), 2448-9
PubMed 11475236
The EWA (estrogen in women with atherosclerosis) study: a randomized study of the use of hormone replacement therapy in women with angiographically verified coronary artery disease. Characteristics of the study population. Effects on lipids and lipoproteins
J Intern Med, 247 (4), 433-41
DOI 10.1046/j.1365-2796.2000.00675.x, PubMed 10792556
The EWA (estrogen in women with atherosclerosis) study: a randomized study of the use of hormone replacement therapy in women with angiographically verified coronary artery disease. Characteristics of the study population. Effects on lipids and lipoproteins
In Journal of internal medicine, Blackwell Scientific Publ., Oxford, 247(2000)nr 4, s.433-443
BIBSYS 010830138