Svein Solheim
- Senior Cardiologist; MD, PhD
- +47 22 11 96 23
Publications 2024
Links Between Adipose Tissue Gene Expression of Gut Leakage Markers, Circulating Levels, Anthropometrics, and Diet in Patients with Coronary Artery Disease
Diabetes Metab Syndr Obes, 17, 2177-2190
DOI 10.2147/DMSO.S438818, PubMed 38827167
Publications 2023
Omega-3 fatty acid supplements and risk of atrial fibrillation and 'micro-atrial fibrillation': A secondary analysis from the OMEMI trial
Clin Nutr, 42 (9), 1657-1660
DOI 10.1016/j.clnu.2023.07.002, PubMed 37515843
Total Bilirubin Yields Prognostic Information Following a Myocardial Infarction in the Elderly
Antioxidants (Basel), 12 (6)
DOI 10.3390/antiox12061157, PubMed 37371887
Sirtuin1, not NAMPT, possesses anti-inflammatory effects in epicardial, pericardial and subcutaneous adipose tissue in patients with CHD
J Transl Med, 21 (1), 644
DOI 10.1186/s12967-023-04518-4, PubMed 37730614
Macrophage polarization markers in subcutaneous, pericardial, and epicardial adipose tissue are altered in patients with coronary heart disease
Front Cardiovasc Med, 10, 1055069
DOI 10.3389/fcvm.2023.1055069, PubMed 36937936
von Willebrand factor, ADAMTS-13, and thrombospondin 1 in relation to clinical outcomes in elderly patients with a recent myocardial infarction
Res Pract Thromb Haemost, 7 (4), 100164
DOI 10.1016/j.rpth.2023.100164, PubMed 37255854
Publications 2022
Screen-Detected Atrial Fibrillation and "Micro-Atrial Fibrillation" and Risk of Cardiovascular Events after Myocardial Infarction in Elderly Patients
Cardiology, 148 (1), 72-77
DOI 10.1159/000528726, PubMed 36538900
Circulating Microvesicles in Association with the NLRP3 Inflammasome in Coronary Thrombi from STEMI Patients
Biomedicines, 10 (9)
DOI 10.3390/biomedicines10092196, PubMed 36140297
Changes in eicosapentaenoic acid and docosahexaenoic acid and risk of cardiovascular events and atrial fibrillation: A secondary analysis of the OMEMI trial
J Intern Med, 291 (5), 637-647
DOI 10.1111/joim.13442, PubMed 34982486
TIMP-1 expression in coronary thrombi associate with myocardial injury in ST-elevation myocardial infarction patients
Coron Artery Dis, 33 (6), 446-455
DOI 10.1097/MCA.0000000000001128, PubMed 35102064
Gene expression of fibrinolytic markers in coronary thrombi
Thromb J, 20 (1), 23
DOI 10.1186/s12959-022-00383-1, PubMed 35488283
The NLRP3 Genetic Variant (rs10754555) Reduces the Risk of Adverse Outcome in Middle-Aged Patients with Chronic Coronary Syndrome
J Immunol Res, 2022, 2366695
DOI 10.1155/2022/2366695, PubMed 36582742
TERT and TET2 Genetic Variants Affect Leukocyte Telomere Length and Clinical Outcome in Coronary Artery Disease Patients-A Possible Link to Clonal Hematopoiesis
Biomedicines, 10 (8)
DOI 10.3390/biomedicines10082027, PubMed 36009574
The NLRP3 inflammasome activation in subcutaneous, epicardial and pericardial adipose tissue in patients with coronary heart disease undergoing coronary by-pass surgery
Atheroscler Plus, 48, 47-54
DOI 10.1016/j.athplu.2022.03.005, PubMed 36644557
Publications 2021
Gut related inflammation and cardiorespiratory fitness in patients with CAD and type 2 diabetes: a sub-study of a randomized controlled trial on exercise training
Diabetol Metab Syndr, 13 (1), 36
DOI 10.1186/s13098-021-00655-2, PubMed 33794977
Gut Leakage Markers in Response to Strenuous Exercise in Patients with Suspected Coronary Artery Disease
Cells, 10 (9)
DOI 10.3390/cells10092193, PubMed 34571843
Rifaximin or Saccharomyces boulardii in heart failure with reduced ejection fraction: Results from the randomized GutHeart trial
EBioMedicine, 70, 103511
DOI 10.1016/j.ebiom.2021.103511, PubMed 34329947
One year of omega 3 polyunsaturated fatty acid supplementation does not reduce circulating prothrombotic microvesicles in elderly subjects after suffering a myocardial infarction
Clin Nutr, 40 (12), 5674-5677
DOI 10.1016/j.clnu.2021.10.007, PubMed 34742136
Biomarkers of ageing and cardiac remodeling are associated with atrial fibrillation
Scand Cardiovasc J, 55 (4), 213-219
DOI 10.1080/14017431.2021.1889653, PubMed 33650449
The Inflammasome Signaling Pathway Is Actively Regulated and Related to Myocardial Damage in Coronary Thrombi from Patients with STEMI
Mediators Inflamm, 2021, 5525917
DOI 10.1155/2021/5525917, PubMed 34135690
Adiponectin in relation to exercise and physical performance in patients with type 2 diabetes and coronary artery disease
Adipocyte, 10 (1), 612-620
DOI 10.1080/21623945.2021.1996699, PubMed 34779349
Publications 2020
Annexin V+ Microvesicles in Children and Adolescents with Type 1 Diabetes: A Prospective Cohort Study
J Diabetes Res, 2020, 7216863
DOI 10.1155/2020/7216863, PubMed 32309448
Procoagulant activity in children and adolescents on intensive insulin therapy
Pediatr Diabetes, 21 (3), 496-504
DOI 10.1111/pedi.12978, PubMed 31943582
Facilitators of and barriers to reducing thirty-day readmissions and improving patient-reported outcomes after surgical aortic valve replacement: a process evaluation of the AVRre trial
BMC Health Serv Res, 20 (1), 256
DOI 10.1186/s12913-020-05125-5, PubMed 32220252
Collagen methionine sulfoxide and glucuronidine/LW-1 are markers of coronary artery disease in long-term survivors with type 1 diabetes. The Dialong study
PLoS One, 15 (5), e0233174
DOI 10.1371/journal.pone.0233174, PubMed 32401813
Effects of n-3 Fatty Acid Supplements in Elderly Patients After Myocardial Infarction: A Randomized, Controlled Trial
Circulation, 143 (6), 528-539
DOI 10.1161/CIRCULATIONAHA.120.052209, PubMed 33191772
Neutrophil extracellular trap components and myocardial recovery in post-ischemic acute heart failure
PLoS One, 15 (10), e0241333
DOI 10.1371/journal.pone.0241333, PubMed 33119664
Double-Stranded DNA and NETs Components in Relation to Clinical Outcome After ST-Elevation Myocardial Infarction
Sci Rep, 10 (1), 5007
DOI 10.1038/s41598-020-61971-7, PubMed 32193509
Reduced leukocyte telomere lengths and sirtuin 1 gene expression in long-term survivors of type 1 diabetes: A Dialong substudy
J Diabetes Investig, 12 (7), 1183-1192
DOI 10.1111/jdi.13470, PubMed 33249778
Shorter Leukocyte Telomere Lengths in Healthy Relatives of Patients with Coronary Heart Disease
Rejuvenation Res, 23 (4), 324-332
DOI 10.1089/rej.2019.2258, PubMed 31805818
Publications 2019
Effects of dietary intervention and n-3 PUFA supplementation on markers of gut-related inflammation and their association with cardiovascular events in a high-risk population
Atherosclerosis, 286, 53-59
DOI 10.1016/j.atherosclerosis.2019.05.004, PubMed 31100620
Elevated levels of circulating microvesicles in coronary artery disease patients with type 2 diabetes and albuminuria: Effects of exercise training
Diab Vasc Dis Res, 16 (5), 431-439
DOI 10.1177/1479164119843094, PubMed 31023084
High Adherence to the Nordic Diet Is Associated with Lower Levels of Total and Platelet-Derived Circulating Microvesicles in a Norwegian Population
Nutrients, 11 (5)
DOI 10.3390/nu11051114, PubMed 31109111
Impact of telephone follow-up and 24/7 hotline on 30-day readmission rates following aortic valve replacement -A randomized controlled trial
Int J Cardiol, 300, 66-72
DOI 10.1016/j.ijcard.2019.07.087, PubMed 31387822
Undiagnosed coronary artery disease in long-term type 1 diabetes. The Dialong study
J Diabetes Complications, 33 (5), 383-389
DOI 10.1016/j.jdiacomp.2019.01.006, PubMed 30846232
Leukocyte telomere length and serum polyunsaturated fatty acids, dietary habits, cardiovascular risk factors and features of myocardial infarction in elderly patients
BMC Geriatr, 19 (1), 376
DOI 10.1186/s12877-019-1383-9, PubMed 31881852
Effects of exercise training on inflammasome-related mediators and their associations to glucometabolic variables in patients with combined coronary artery disease and type 2 diabetes mellitus: Sub-study of a randomized control trial
Diab Vasc Dis Res, 16 (4), 360-368
DOI 10.1177/1479164119836922, PubMed 30939905
Effects of exercise training on markers of adipose tissue remodeling in patients with coronary artery disease and type 2 diabetes mellitus: sub study of the randomized controlled EXCADI trial
Diabetol Metab Syndr, 11, 109
DOI 10.1186/s13098-019-0508-9, PubMed 31890043
Publications 2018
Markers of metabolic endotoxemia as related to metabolic syndrome in an elderly male population at high cardiovascular risk: a cross-sectional study
Diabetol Metab Syndr, 10, 59
DOI 10.1186/s13098-018-0360-3, PubMed 30038669
Thirty-day readmissions in surgical and transcatheter aortic valve replacement: A systematic review and meta-analysis
Int J Cardiol, 268, 85-91
DOI 10.1016/j.ijcard.2018.05.026, PubMed 29779575
Markers of neutrophil extracellular traps are associated with adverse clinical outcome in stable coronary artery disease
Eur J Prev Cardiol, 25 (7), 762-769
DOI 10.1177/2047487318760618, PubMed 29473463
Towards a refined understanding of the use of coastal zones in the Mesolithic: New investigations on human-environment interactions in Telemark, southeastern Norway
J. Archaeol. Sci.-Rep., 17, 839-851
DOI 10.1016/j.jasrep.2017.12.045
Publications 2017
Procoagulant activity in patients with combined type 2 diabetes and coronary artery disease: No effects of long-term exercise training
Diab Vasc Dis Res, 14 (2), 144-151
DOI 10.1177/1479164116679080, PubMed 28111966
Reduced endothelial activation after exercise is associated with improved HbA1c in patients with type 2 diabetes and coronary artery disease
Diab Vasc Dis Res, 14 (2), 94-103
DOI 10.1177/1479164116679077, PubMed 28111980
Platelet-, monocyte-derived and tissue factor-carrying circulating microparticles are related to acute myocardial infarction severity
PLoS One, 12 (2), e0172558
DOI 10.1371/journal.pone.0172558, PubMed 28207887
Determining the impact of 24/7 phone support on hospital readmissions after aortic valve replacement surgery (the AVRre study): study protocol for a randomised controlled trial
Trials, 18 (1), 246
DOI 10.1186/s13063-017-1971-y, PubMed 28693599
Galectin-3, a marker of cardiac remodeling, is inversely related to serum levels of marine omega-3 fatty acids. A cross-sectional study
JRSM Cardiovasc Dis, 6, 2048004017729984
DOI 10.1177/2048004017729984, PubMed 28932392
A Double-Blinded Randomized Study Investigating a Possible Anti-Inflammatory Effect of Saxagliptin versus Placebo as Add-On Therapy in Patients with Both Type 2 Diabetes And Stable Coronary Artery Disease
Mediators Inflamm, 2017, 5380638
DOI 10.1155/2017/5380638, PubMed 28596642
Publications 2016
Effects of exercise training on carotid intima-media thickness in patients with type 2 diabetes and coronary artery disease. Influence of carotid plaques
Cardiovasc Diabetol, 15, 13
DOI 10.1186/s12933-016-0336-2, PubMed 26801098
The Time Course of Markers of Neutrophil Extracellular Traps in Patients Undergoing Revascularisation for Acute Myocardial Infarction or Stable Angina Pectoris
Mediators Inflamm, 2016, 2182358
DOI 10.1155/2016/2182358, PubMed 28074081
Serum Fatty Acids, Traditional Risk Factors, and Comorbidity as Related to Myocardial Injury in an Elderly Population with Acute Myocardial Infarction
J Lipids, 2016, 4945720
DOI 10.1155/2016/4945720, PubMed 26989512
[Clinical research on elderly]
Tidsskr Nor Laegeforen, 136 (3), 208
DOI 10.4045/tidsskr.15.1300, PubMed 26860377
Effects of long-term exercise training on adipose tissue expression of fractalkine and MCP-1 in patients with type 2 diabetes and stable coronary artery disease: a substudy of a randomized controlled trial
Diabetes Metab Syndr Obes, 9, 55-62
DOI 10.2147/DMSO.S96299, PubMed 27042130
Publications 2015
Effects of exercise training on HbA1c and VO2peak in patients with type 2 diabetes and coronary artery disease: A randomised clinical trial
Diab Vasc Dis Res, 12 (5), 325-33
DOI 10.1177/1479164115590552, PubMed 26092822
New model of secondary cardiovascular prevention for patients after acute coronary syndromes in Poland with regard to Norwegian experiences
Kardiol Pol, 74 (2), 101-3
DOI 10.5603/KP.a2015.0176, PubMed 26365935
The Effect of Intracoronary Stem Cell Injection on Markers of Leukocyte Activation in Acute Myocardial Infarction
Cardiol Res, 6 (1), 209-215
DOI 10.14740/cr375w, PubMed 28197227
Associations between circulating proteins and corresponding genes expressed in coronary thrombi in patients with acute myocardial infarction
Thromb Res, 136 (6), 1240-4
DOI 10.1016/j.thromres.2015.10.005, PubMed 26475405
Effects on serum fractalkine by diet and omega-3 fatty acid intervention: relation to clinical outcome
Mediators Inflamm, 2015, 373070
DOI 10.1155/2015/373070, PubMed 25733777
Publications 2014
Insulin levels and HOMA index are associated with exercise capacity in patients with type 2 diabetes and coronary artery disease
Diabetol Metab Syndr, 6 (1), 36
DOI 10.1186/1758-5996-6-36, PubMed 24612649
The influence of autologous bone marrow stem cell transplantation on matrix metalloproteinases in patients treated for acute ST-elevation myocardial infarction
Mediators Inflamm, 2014, 385901
DOI 10.1155/2014/385901, PubMed 25294955
Genes expressed in coronary thrombi are associated with ischemic time in patients with acute myocardial infarction
Thromb Res, 135 (2), 329-33
DOI 10.1016/j.thromres.2014.11.028, PubMed 25496999
The time profile of Pentraxin 3 in patients with acute ST-elevation myocardial infarction and stable angina pectoris undergoing percutaneous coronary intervention
Mediators Inflamm, 2014, 608414
DOI 10.1155/2014/608414, PubMed 24737925
Effects of ω3 supplementation in elderly patients with acute myocardial infarction: design of a prospective randomized placebo controlled study
BMC Geriatr, 14, 74
DOI 10.1186/1471-2318-14-74, PubMed 24928284
Fractalkine levels are elevated early after PCI-treated ST-elevation myocardial infarction; no influence of autologous bone marrow derived stem cell injection
Cytokine, 69 (1), 131-5
DOI 10.1016/j.cyto.2014.05.022, PubMed 24930044
Publications 2013
Perfusion MRI at rest in subacute and chronic myocardial infarct
Acta Radiol, 54 (4), 401-11
DOI 10.1177/0284185113475605, PubMed 23401603
Prothrombotic markers in patients with acute myocardial infarction and left ventricular thrombus formation treated with pci and dual antiplatelet therapy
Thromb J, 11 (1), 1
DOI 10.1186/1477-9560-11-1, PubMed 23311309
Publications 2012
Increased circulating mitochondrial DNA after myocardial infarction
Int J Cardiol, 158 (1), 132-4
DOI 10.1016/j.ijcard.2012.04.047, PubMed 22578950
Publications 2011
Circulating CD34⁺ progenitor cells and growth factors in patients treated with PCI for acute myocardial infarction or stable angina pectoris
Scand J Clin Lab Invest, 71 (4), 322-9
DOI 10.3109/00365513.2011.565367, PubMed 21463159
Regional myocardial function after intracoronary bone marrow cell injection in reperfused anterior wall infarction - a cardiovascular magnetic resonance tagging study
J Cardiovasc Magn Reson, 13 (1), 22
DOI 10.1186/1532-429X-13-22, PubMed 21414223
The influence of intracoronary injection of bone marrow cells on prothrombotic markers in patients with acute myocardial infarction
Thromb Res, 130 (5), 765-8
DOI 10.1016/j.thromres.2011.11.045, PubMed 22192151
Publications 2010
Left ventricular systolic and diastolic function improve after acute myocardial infarction treated with acute percutaneous coronary intervention, but are not influenced by intracoronary injection of autologous mononuclear bone marrow cells: a 3 year serial echocardiographic sub-study of the randomized-controlled ASTAMI study
Eur J Echocardiogr, 12 (2), 98-106
DOI 10.1093/ejechocard/jeq116, PubMed 20851818
Cell treatment after acute myocardial infarction prevents early decline in circulating IGF-1
Scand Cardiovasc J, 44 (5), 267-72
DOI 10.3109/14017431.2010.490949, PubMed 21080844
Frequency of left ventricular thrombus in patients with anterior wall acute myocardial infarction treated with percutaneous coronary intervention and dual antiplatelet therapy
Am J Cardiol, 106 (9), 1197-200
DOI 10.1016/j.amjcard.2010.06.043, PubMed 21029812
Training auscultatory skills: computer simulated heart sounds or additional bedside training? A randomized trial on third-year medical students
BMC Med Educ, 10, 3
DOI 10.1186/1472-6920-10-3, PubMed 20082701
Prediction of cardiovascular events by matrix metalloproteinase (MMP)-9 in elderly men
Thromb Haemost, 103 (3), 679-81
DOI 10.1160/TH09-05-0317, PubMed 20076844
Publications 2009
Long-term results after intracoronary injection of autologous mononuclear bone marrow cells in acute myocardial infarction: the ASTAMI randomised, controlled study
Heart, 95 (24), 1983-9
DOI 10.1136/hrt.2009.178913, PubMed 19833610
The profile of circulating metalloproteinases after PCI in patients with acute myocardial infarction or stable angina
Thromb Res, 124 (5), 560-4
DOI 10.1016/j.thromres.2009.04.001, PubMed 19410278
Age and stress related phenotypical changes in bone marrow CD34+ cells
Scand J Clin Lab Invest, 69 (1), 79-84
DOI 10.1080/00365510802419447, PubMed 18836945
Publications 2008
[Occurrence of arrhythmias related to treatment of myocardial infarction]
Tidsskr Nor Laegeforen, 128 (19), 2163-6
PubMed 18846137
Long-term influence of diet and/or omega-3 fatty acids on matrix metalloproteinase-9 and pregnancy-associated plasma protein-A in men at high risk of coronary heart disease
Scand J Clin Lab Invest, 68 (3), 177-84
DOI 10.1080/00365510701663350, PubMed 17934973
Anterior myocardial infarction with acute percutaneous coronary intervention and intracoronary injection of autologous mononuclear bone marrow cells: safety, clinical outcome, and serial changes in left ventricular function during 12-months' follow-up
J Am Coll Cardiol, 51 (6), 674-6
DOI 10.1016/j.jacc.2007.10.032, PubMed 18261689
Inflammation in various stages of coronary heart disease
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 569, 1 b. (flere pag.)
BIBSYS 080111351, ISBN 978-82-8072-880-7
Inflammatory responses after percutaneous coronary intervention in patients with acute myocardial infarction or stable angina pectoris
Scand J Clin Lab Invest, 68 (7), 555-62
DOI 10.1080/00365510701884584, PubMed 19378426
Inflammatory responses after intracoronary injection of autologous mononuclear bone marrow cells in patients with acute myocardial infarction
Am Heart J, 155 (1), 55.e1-9
DOI 10.1016/j.ahj.2007.10.005, PubMed 18082489
Publications 2007
Exercise capacity and quality of life after intracoronary injection of autologous mononuclear bone marrow cells in acute myocardial infarction: results from the Autologous Stem cell Transplantation in Acute Myocardial Infarction (ASTAMI) randomized controlled trial
Am Heart J, 154 (4), 710.e1-8
DOI 10.1016/j.ahj.2007.07.003, PubMed 17892996
Publications 2006
Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction
N Engl J Med, 355 (12), 1199-209
DOI 10.1056/NEJMoa055706, PubMed 16990383
No difference in the effects of clopidogrel and aspirin on inflammatory markers in patients with coronary heart disease
Thromb Haemost, 96 (5), 660-4
DOI 10.1160/TH06-06-0337, PubMed 17080224
Publications 2005
Autologous stem cell transplantation in acute myocardial infarction: The ASTAMI randomized controlled trial. Intracoronary transplantation of autologous mononuclear bone marrow cells, study design and safety aspects
Scand Cardiovasc J, 39 (3), 150-8
DOI 10.1080/14017430510009131, PubMed 16152682
Publications 2004
Serum levels of interleukin-10 are inversely related to future events in patients with acute myocardial infarction
J Thromb Haemost, 2 (2), 350-2
DOI 10.1111/j.1538-7933.2004.0584c.x, PubMed 14996010
Publications 2003
Influence of aspirin on inflammatory markers in patients after acute myocardial infarction
Am J Cardiol, 92 (7), 843-5
DOI 10.1016/s0002-9149(03)00897-x, PubMed 14516890
Publications 2001
Reduced levels of TNF alpha in hypercholesterolemic individuals after treatment with pravastatin for 8 weeks
Atherosclerosis, 157 (2), 411-5
DOI 10.1016/s0021-9150(00)00725-5, PubMed 11472741
Publications 2000
[Can radiotherapy reduce the frequency of restenosis after coronary angioplasty?]
Tidsskr Nor Laegeforen, 120 (6), 707-10
PubMed 10806885