Peder Langeland Myhre
- Associate Professor; MD, PhD
- +47 930 25 644
Publications 2024
Predictors of coronary atherosclerosis in middle-aged and older athletes: the MARC-2 study
Eur Heart J Cardiovasc Imaging (in press)
DOI 10.1093/ehjci/jeae317, PubMed 39657626
[Not Available]
Tidsskr Nor Laegeforen, 144
DOI 10.4045/tidsskr.24.0133, PubMed 38738570
Reply to the letter regarding the article 'Changes in 6-min walk test is an independent predictor of death in chronic heart failure with reduced ejection fraction'
Eur J Heart Fail, 26 (10), 2299-2300
DOI 10.1002/ejhf.3448, PubMed 39221640
NT-proBNP and Cardiac Troponin I, but Not Cardiac Troponin T, Are Associated With 7-Year Changes in Cardiac Structure and Function in Older Adults: The ARIC Study
Circulation, 150 (23), 1847-1857
DOI 10.1161/CIRCULATIONAHA.124.069735, PubMed 39315431
Concordance of left ventricular volumes and function measurements between two human readers, a fully automated AI algorithm, and the 3D heart model
Front Cardiovasc Med, 11, 1400333
DOI 10.3389/fcvm.2024.1400333, PubMed 39081366
Changes in 6-min walk test is an independent predictor of death in chronic heart failure with reduced ejection fraction
Eur J Heart Fail (in press)
DOI 10.1002/ejhf.3391, PubMed 39058228
Angiotensin Receptor Neprilysin Inhibition Across Ejection Fraction and Acuity Spectra in Heart Failure
JACC Heart Fail, 12 (3), 583-587
DOI 10.1016/j.jchf.2023.11.021, PubMed 38276934
Ongoing Enigma of NT-proBNP in HFpEF: Insights From Proteomics
Circ Heart Fail, 17 (2), e011428
DOI 10.1161/CIRCHEARTFAILURE.123.011428, PubMed 38299326
Digital tools in heart failure: addressing unmet needs
Lancet Digit Health, 6 (10), e755-e766
DOI 10.1016/S2589-7500(24)00158-4, PubMed 39214764
Natriuretic Peptides, Kidney Function, and Clinical Outcomes in Heart Failure With Preserved Ejection Fraction
JACC Heart Fail (in press)
DOI 10.1016/j.jchf.2024.08.009, PubMed 39365237
Trans-Cardiac Gradient of Secretoneurin in Patients with Takotsubo Syndrome
Cardiology, 149 (5), 466-471
DOI 10.1159/000539094, PubMed 38663366
Large scale plasma proteomics identifies novel proteins and protein networks associated with heart failure development
Nat Commun, 15 (1), 528
DOI 10.1038/s41467-023-44680-3, PubMed 38225249
N-terminal pro-B-type natriuretic peptide levels vary by ethnicity and are associated with insulin sensitivity after gestational diabetes mellitus
Cardiovasc Diabetol, 23 (1), 284
DOI 10.1186/s12933-024-02349-1, PubMed 39097697
Associations Between Biomarkers of Myocardial Injury and Systemic Inflammation and Risk of Incident Ventricular Arrhythmia
JACC Clin Electrophysiol, 10 (9), 2021-2032
DOI 10.1016/j.jacep.2024.04.017, PubMed 38904572
Trajectory of cardiac troponin T following moderate-to-severe COVID-19 and the association with cardiac abnormalities
BMC Cardiovasc Disord, 24 (1), 206
DOI 10.1186/s12872-024-03854-7, PubMed 38614990
Publications 2023
Early versus delayed coronary angiography in patients with out-of-hospital cardiac arrest and no ST-segment elevation: a systematic review and meta-analysis of randomized controlled trials
Clin Res Cardiol, 113 (4), 561-569
DOI 10.1007/s00392-023-02264-7, PubMed 37495798
Lung Ultrasound to Assess Pulmonary Congestion in Patients with Acute Exacerbation of COPD
Int J Chron Obstruct Pulmon Dis, 18, 693-703
DOI 10.2147/COPD.S396855, PubMed 37128214
Recent successes in heart failure treatment
Nat Med, 29 (10), 2424-2437
DOI 10.1038/s41591-023-02567-2, PubMed 37814060
Left ventricular ejection fraction in women: when normal isn't normal
Heart, 109 (21), 1584-1585
DOI 10.1136/heartjnl-2023-322924, PubMed 37438053
Heart Failure Phenotypes According to Natriuretic Peptide Trajectory Following Initiation of Sacubitril/Valsartan
JACC Heart Fail, 11 (7), 855-858
DOI 10.1016/j.jchf.2023.03.006, PubMed 37115131
Omega-3 Fatty Acids and Atrial Fibrillation: The Difference Between Dietary Consumption and Supplementation
J Am Coll Cardiol, 82 (21), e205
DOI 10.1016/j.jacc.2023.08.057, PubMed 37968026
Omega-3 fatty acid supplements and risk of atrial fibrillation and 'micro-atrial fibrillation': A secondary analysis from the OMEMI trial
Clin Nutr, 42 (9), 1657-1660
DOI 10.1016/j.clnu.2023.07.002, PubMed 37515843
External validation of a deep learning algorithm for automated echocardiographic strain measurements
Eur Heart J Digit Health, 5 (1), 60-68
DOI 10.1093/ehjdh/ztad072, PubMed 38264705
Changes in mid-regional pro-adrenomedullin during treatment with sacubitril/valsartan
Eur J Heart Fail, 25 (8), 1396-1405
DOI 10.1002/ejhf.2957, PubMed 37401523
Fine-Tuning Risk Stratification in Heart Failure: Does It Improve Patient Care?
JACC Heart Fail, 11 (6), 675-677
DOI 10.1016/j.jchf.2023.02.004, PubMed 37052547
Total Bilirubin Yields Prognostic Information Following a Myocardial Infarction in the Elderly
Antioxidants (Basel), 12 (6)
DOI 10.3390/antiox12061157, PubMed 37371887
Longitudinal whole blood transcriptomic analysis characterizes neutrophil activation and interferon signaling in moderate and severe COVID-19
Sci Rep, 13 (1), 10368
DOI 10.1038/s41598-023-37606-y, PubMed 37365222
Author Correction: Longitudinal whole blood transcriptomic analysis characterizes neutrophil activation and interferon signaling in moderate and severe COVID-19
Sci Rep, 13 (1), 12691
DOI 10.1038/s41598-023-39872-2, PubMed 37542160
Soluble ST2 in Heart Failure: A Clinical Role beyond B-Type Natriuretic Peptide
J Cardiovasc Dev Dis, 10 (11)
DOI 10.3390/jcdd10110468, PubMed 37998526
New centres to carry out more clinical trials in Norway
Tidsskr Nor Laegeforen, 143 (2)
DOI 10.4045/tidsskr.22.0722, PubMed 36718905
N-terminal pro-B-type natriuretic peptide for prediction of ventricular arrhythmias: Data from the SMASH study
Clin Cardiol, 46 (8), 989-996
DOI 10.1002/clc.24074, PubMed 37400982
Re: Detailed association between B-type natriuretic peptide levels and ventricular tachyarrhythmia
Clin Cardiol, 46 (12), 1604-1605
DOI 10.1002/clc.24145, PubMed 37872822
The clinical importance of high-sensitivity cardiac troponin measurements for risk prediction in non-cardiac surgery
Expert Rev Mol Diagn, 23 (6), 535-544
DOI 10.1080/14737159.2023.2211267, PubMed 37162108
von Willebrand factor, ADAMTS-13, and thrombospondin 1 in relation to clinical outcomes in elderly patients with a recent myocardial infarction
Res Pract Thromb Haemost, 7 (4), 100164
DOI 10.1016/j.rpth.2023.100164, PubMed 37255854
Minor Myocardial Scars in Association with Cardiopulmonary Function after COVID-19
Cardiology, 148 (4), 300-306
DOI 10.1159/000530942, PubMed 37231850
Publications 2022
Screen-Detected Atrial Fibrillation and "Micro-Atrial Fibrillation" and Risk of Cardiovascular Events after Myocardial Infarction in Elderly Patients
Cardiology, 148 (1), 72-77
DOI 10.1159/000528726, PubMed 36538900
Do omega-3 fatty acids increase risk of atrial fibrillation?
Curr Opin Clin Nutr Metab Care, 26 (2), 78-82
DOI 10.1097/MCO.0000000000000907, PubMed 36892957
Left atrial inflow propagation velocity derived by color M-mode Doppler in acute heart failure
Int J Cardiovasc Imaging, 38 (10), 2155-2165
DOI 10.1007/s10554-022-02614-y, PubMed 37726456
Sex and Race Differences in N-Terminal Pro-B-type Natriuretic Peptide Concentration and Absolute Risk of Heart Failure in the Community
JAMA Cardiol, 7 (6), 623-631
DOI 10.1001/jamacardio.2022.0680, PubMed 35476049
Changes in cardiac biomarkers in association with alterations in cardiac structure and function, and health status in heart failure with reduced ejection fraction: the EVALUATE-HF trial
Eur J Heart Fail, 24 (7), 1200-1208
DOI 10.1002/ejhf.2541, PubMed 35560696
Changes in eicosapentaenoic acid and docosahexaenoic acid and risk of cardiovascular events and atrial fibrillation: A secondary analysis of the OMEMI trial
J Intern Med, 291 (5), 637-647
DOI 10.1111/joim.13442, PubMed 34982486
Comparative Effect of Angiotensin Receptor Neprilysin Inhibition on B-type Natriuretic Peptide Levels Measured by Three Different Assays: The PROVE-HF Study
Clin Chem, 68 (11), 1391-1398
DOI 10.1093/clinchem/hvac148, PubMed 36103292
Early B-Type Natriuretic Peptide Change in HFrEF Patients Treated With Sacubitril/Valsartan: A Pooled Analysis of EVALUATE-HF and PROVE-HF
JACC Heart Fail, 10 (2), 119-128
DOI 10.1016/j.jchf.2021.09.007, PubMed 35115085
Cardiac troponin T and NT-proBNP for detecting myocardial ischemia in suspected chronic coronary syndrome
Int J Cardiol, 361, 14-17
DOI 10.1016/j.ijcard.2022.05.027, PubMed 35577165
Influence of NT-proBNP on Efficacy of Dapagliflozin in Heart Failure With Mildly Reduced or Preserved Ejection Fraction
JACC Heart Fail, 10 (12), 902-913
DOI 10.1016/j.jchf.2022.08.007, PubMed 36114137
QRS fragmentation is associated with increased risk of ventricular arrhythmias in high-risk patients; Data from the SMASH 1 Study
Ann Noninvasive Electrocardiol, 27 (5), e12985
DOI 10.1111/anec.12985, PubMed 35839068
Cardiac troponin I and T for ruling out coronary artery disease in suspected chronic coronary syndrome
Sci Rep, 12 (1), 945
DOI 10.1038/s41598-022-04850-7, PubMed 35042885
Changes in cardiac structure and function from 3 to 12 months after hospitalization for COVID-19
Clin Cardiol, 45 (10), 1044-1052
DOI 10.1002/clc.23891, PubMed 35920837
Publications 2021
Spironolactone in Patients With Heart Failure, Preserved Ejection Fraction, and Worsening Renal Function
J Am Coll Cardiol, 77 (9), 1211-1221
DOI 10.1016/j.jacc.2020.12.057, PubMed 33663739
NT-proBNP Response to Heart Failure Therapies: An Imperfect Surrogate
J Am Coll Cardiol, 78 (13), 1333-1336
DOI 10.1016/j.jacc.2021.07.045, PubMed 34556319
Assessing congestion in acute heart failure using cardiac and lung ultrasound - a review
Expert Rev Cardiovasc Ther, 19 (2), 165-176
DOI 10.1080/14779072.2021.1865155, PubMed 33432851
Biomarkers of ageing and cardiac remodeling are associated with atrial fibrillation
Scand Cardiovasc J, 55 (4), 213-219
DOI 10.1080/14017431.2021.1889653, PubMed 33650449
[Myhre, Seljeflot and Arnesen respond]
Tidsskr Nor Laegeforen, 141 (10)
DOI 10.4045/tidsskr.21.0470, PubMed 34182730
Cardiac pathology 6 months after hospitalization for COVID-19 and association with the acute disease severity
Am Heart J, 242, 61-70
DOI 10.1016/j.ahj.2021.08.001, PubMed 34400140
Diagnostic Thresholds for Pre-Diabetes Mellitus and Diabetes Mellitus and Subclinical Cardiac Disease in the General Population: Data From the ACE 1950 Study
J Am Heart Assoc, 10 (11), e020447
DOI 10.1161/JAHA.120.020447, PubMed 33998259
Performance of a Novel Research-Use-Only Secretoneurin ELISA in Patients with Suspected Acute Coronary Syndrome: Comparison with an Established Secretoneurin Radioimmunoassay
Cardiology, 146 (5), 566-574
DOI 10.1159/000517444, PubMed 34284402
SARS-CoV-2 Viremia is Associated With Inflammatory, But Not Cardiovascular Biomarkers, in Patients Hospitalized for COVID-19
J Am Heart Assoc, 10 (9), e019756
DOI 10.1161/JAHA.120.019756, PubMed 33596668
Omega-3 supplements do not prevent cardiovascular disease
Tidsskr Nor Laegeforen, 141 (6)
DOI 10.4045/tidsskr.21.0033, PubMed 33876607
Omega-3 supplements do not prevent cardiovascular disease
Tidsskr. Nor. Laegeforen., 141 (6), 536-538
Management of hypertension in heart failure with preserved ejection fraction: is there a blood pressure goal?
Curr Opin Cardiol, 36 (4), 413-419
DOI 10.1097/HCO.0000000000000852, PubMed 33709982
Serum Levels of Dihomo-Gamma (γ)-Linolenic Acid (DGLA) Are Inversely Associated with Linoleic Acid and Total Death in Elderly Patients with a Recent Myocardial Infarction
Nutrients, 13 (10)
DOI 10.3390/nu13103475, PubMed 34684479
Soluble ST2 concentrations associate with in-hospital mortality and need for mechanical ventilation in unselected patients with COVID-19
Open Heart, 8 (2)
DOI 10.1136/openhrt-2021-001884, PubMed 34933965
Severe Acute Respiratory Syndrome Coronavirus 2 RNA in Plasma Is Associated With Intensive Care Unit Admission and Mortality in Patients Hospitalized With Coronavirus Disease 2019
Clin Infect Dis, 73 (3), e799-e802
DOI 10.1093/cid/ciaa1338, PubMed 32888003
Publications 2020
Very Long Chain Marine n-3 Polyunsaturated Fatty Acids in Atherothrombotic Heart Disease. A Brief Review, with a Focus on Metabolic Effects
Nutrients, 12 (10)
DOI 10.3390/nu12103014, PubMed 33008057
High-sensitivity cardiac troponin T and N-terminal pro-B-type natriuretic peptide in acute heart failure: Data from the ACE 2 study
Clin Biochem, 88, 30-36
DOI 10.1016/j.clinbiochem.2020.11.009, PubMed 33245872
The Challenges of NT-proBNP Testing in HFpEF: Shooting Arrows in the Wind
JACC Heart Fail, 8 (5), 382-385
DOI 10.1016/j.jchf.2020.03.003, PubMed 32241618
Effects of n-3 Fatty Acid Supplements in Elderly Patients After Myocardial Infarction: A Randomized, Controlled Trial
Circulation, 143 (6), 528-539
DOI 10.1161/CIRCULATIONAHA.120.052209, PubMed 33191772
Cardiovascular Hospitalizations, Influenza Activity, and COVID-19 Measures
Circulation, 142 (13), 1302-1304
DOI 10.1161/CIRCULATIONAHA.120.049118, PubMed 32757861
Removing stable and adding precision to chronic coronary artery disease
Int J Cardiol, 316, 54-56
DOI 10.1016/j.ijcard.2020.04.063, PubMed 32360648
Growth Differentiation Factor 15 Provides Prognostic Information Superior to Established Cardiovascular and Inflammatory Biomarkers in Unselected Patients Hospitalized With COVID-19
Circulation, 142 (22), 2128-2137
DOI 10.1161/CIRCULATIONAHA.120.050360, PubMed 33058695
Mechanistic Effects of Spironolactone on Cardiovascular and Renal Biomarkers in Heart Failure With Preserved Ejection Fraction: A TOPCAT Biorepository Study
Circ Heart Fail, 13 (1), e006638
DOI 10.1161/CIRCHEARTFAILURE.119.006638, PubMed 31957468
Neprilysin and Corin: It Takes Two to Tango
JACC Heart Fail, 9 (2), 96-99
DOI 10.1016/j.jchf.2020.08.018, PubMed 33189628
Established Cardiovascular Biomarkers Provide Limited Prognostic Information in Unselected Patients Hospitalized With COVID-19
Circulation, 142 (19), 1878-1880
DOI 10.1161/CIRCULATIONAHA.120.050089, PubMed 32910681
Application of Diagnostic Algorithms for Heart Failure With Preserved Ejection Fraction to the Community
JACC Heart Fail, 8 (8), 640-653
DOI 10.1016/j.jchf.2020.03.013, PubMed 32535127
A single-centre, prospective cohort study of COVID-19 patients admitted to ICU for mechanical ventilatory support
Acta Anaesthesiol Scand, 65 (3), 351-359
DOI 10.1111/aas.13726, PubMed 33128800
Differential associations of cardiac troponin T and cardiac troponin I with coronary artery pathology and dynamics in response to short-duration exercise
Clin Biochem, 88, 23-29
DOI 10.1016/j.clinbiochem.2020.11.005, PubMed 33245871
Reply: The complementary role of cardiac troponin I and cardiac troponin T
Clin Biochem, 78, 42
DOI 10.1016/j.clinbiochem.2020.02.011, PubMed 32088145
Publications 2019
Efficacy and Safety of Spironolactone in Patients With HFpEF and Chronic Kidney Disease
JACC Heart Fail, 7 (1), 25-32
DOI 10.1016/j.jchf.2018.10.017, PubMed 30606484
Circulating secretoneurin concentrations in patients with moderate to severe aortic stenosis
Clin Biochem, 71, 17-23
DOI 10.1016/j.clinbiochem.2019.06.008, PubMed 31228433
Circulating Secretoneurin Concentrations After Cardiac Surgery: Data From the FINNish Acute Kidney Injury Heart Study
Crit Care Med, 47 (5), e412-e419
DOI 10.1097/CCM.0000000000003670, PubMed 30730440
High Adherence to the Nordic Diet Is Associated with Lower Levels of Total and Platelet-Derived Circulating Microvesicles in a Norwegian Population
Nutrients, 11 (5)
DOI 10.3390/nu11051114, PubMed 31109111
Leukocyte telomere length and serum polyunsaturated fatty acids, dietary habits, cardiovascular risk factors and features of myocardial infarction in elderly patients
BMC Geriatr, 19 (1), 376
DOI 10.1186/s12877-019-1383-9, PubMed 31881852
Association Between Circulating Troponin Concentrations, Left Ventricular Systolic and Diastolic Functions, and Incident Heart Failure in Older Adults
JAMA Cardiol, 4 (10), 997-1006
DOI 10.1001/jamacardio.2019.3113, PubMed 31483438
De novo heart failure: where the journey begins
Eur J Heart Fail, 21 (10), 1245-1247
DOI 10.1002/ejhf.1586, PubMed 31496006
Cardiac imaging and circulating biomarkers for primary prevention in the era of precision medicine
Expert Rev. Precis. Med. Drug Dev., 4 (5), 299-308
DOI 10.1080/23808993.2019.1660162
B-Type Natriuretic Peptide During Treatment With Sacubitril/Valsartan: The PARADIGM-HF Trial
J Am Coll Cardiol, 73 (11), 1264-1272
DOI 10.1016/j.jacc.2019.01.018, PubMed 30846338
Application of the H2 FPEF score to a global clinical trial of patients with heart failure with preserved ejection fraction: the TOPCAT trial
Eur J Heart Fail, 21 (10), 1288-1291
DOI 10.1002/ejhf.1542, PubMed 31332920
Diagnosing heart failure with preserved ejection fraction in 2019: the search for a gold standard
Eur J Heart Fail, 22 (3), 422-424
DOI 10.1002/ejhf.1638, PubMed 31863672
Reply: Searching for Optimal Prognostic Marker of Heart Failure Progression in the Era of ARNI
J Am Coll Cardiol, 74 (1), 165-166
DOI 10.1016/j.jacc.2019.05.006, PubMed 31272546
Secretoneurin Is an Endogenous Calcium/Calmodulin-Dependent Protein Kinase II Inhibitor That Attenuates Ca2+-Dependent Arrhythmia
Circ Arrhythm Electrophysiol, 12 (4), e007045
DOI 10.1161/CIRCEP.118.007045, PubMed 30943765
Current Smoking Is Associated With Lower Concentrations of High-Sensitivity Cardiac Troponin T in Patients With Stable Coronary Artery Disease: The PEACE Trial
Circulation, 140 (24), 2044-2046
DOI 10.1161/CIRCULATIONAHA.119.041991, PubMed 31815543
Superiority of high sensitivity cardiac troponin T vs. I for long-term prognostic value in patients with chest pain; data from the Akershus cardiac Examination (ACE) 3 study
Clin Biochem, 78, 10-17
DOI 10.1016/j.clinbiochem.2019.12.016, PubMed 31899280
Publications 2018
Novel biomarkers of cardiovascular disease: Applications in clinical practice
Crit Rev Clin Lab Sci, 56 (1), 33-60
DOI 10.1080/10408363.2018.1525335, PubMed 30457415
Cardiac Troponin I and Risk of Cardiac Events in Patients With Heart Failure and Preserved Ejection Fraction
Circ Heart Fail, 11 (11), e005312
DOI 10.1161/CIRCHEARTFAILURE.118.005312, PubMed 30571192
Cardiac Troponin T Concentrations, Reversible Myocardial Ischemia, and Indices of Left Ventricular Remodeling in Patients with Suspected Stable Angina Pectoris: a DOPPLER-CIP Substudy
Clin Chem, 64 (9), 1370-1379
DOI 10.1373/clinchem.2018.288894, PubMed 29959147
Association of Natriuretic Peptides With Cardiovascular Prognosis in Heart Failure With Preserved Ejection Fraction: Secondary Analysis of the TOPCAT Randomized Clinical Trial
JAMA Cardiol, 3 (10), 1000-1005
DOI 10.1001/jamacardio.2018.2568, PubMed 30140899
Prognostic and diagnostic significance of mid-regional pro-atrial natriuretic peptide in acute exacerbation of chronic obstructive pulmonary disease and acute heart failure: data from the ACE 2 Study
Biomarkers, 23 (7), 654-663
DOI 10.1080/1354750X.2018.1474258, PubMed 29733687
Publications 2017
Platelet-, monocyte-derived and tissue factor-carrying circulating microparticles are related to acute myocardial infarction severity
PLoS One, 12 (2), e0172558
DOI 10.1371/journal.pone.0172558, PubMed 28207887
[Not Available]
Tidsskr Nor Laegeforen, 137 (20)
DOI 10.4045/tidsskr.17.0749, PubMed 29094587
Circulating chromogranin B levels in patients with acute respiratory failure: data from the FINNALI Study
Biomarkers, 22 (8), 775-781
DOI 10.1080/1354750X.2016.1269200, PubMed 28049363
Mid-regional pro-adrenomedullin in patients with acute dyspnea: Data from the Akershus Cardiac Examination (ACE) 2 Study
Clin Biochem, 50 (7-8), 394-400
DOI 10.1016/j.clinbiochem.2016.12.010, PubMed 28065681
Publications 2016
Serum Fatty Acids, Traditional Risk Factors, and Comorbidity as Related to Myocardial Injury in an Elderly Population with Acute Myocardial Infarction
J Lipids, 2016, 4945720
DOI 10.1155/2016/4945720, PubMed 26989512
[Clinical research on elderly]
Tidsskr Nor Laegeforen, 136 (3), 208
DOI 10.4045/tidsskr.15.1300, PubMed 26860377
Prognostic Value of Secretoneurin in Patients with Acute Respiratory Failure: Data from the FINNALI Study
Clin Chem, 62 (10), 1380-9
DOI 10.1373/clinchem.2016.258764, PubMed 27540029
NT-proBNP in patients with out-of-hospital cardiac arrest: Results from the FINNRESUSCI Study
Resuscitation, 104, 12-8
DOI 10.1016/j.resuscitation.2016.04.007, PubMed 27109503
Publications 2014
Effects of ω3 supplementation in elderly patients with acute myocardial infarction: design of a prospective randomized placebo controlled study
BMC Geriatr, 14, 74
DOI 10.1186/1471-2318-14-74, PubMed 24928284