Publications by Trevor Clancy or Per Olaf Ekstrøm or Sigve Nakken

155 publications found

Publications 2026

1. Abdallah M, Nakken S, Georges M, Bierkens M, Galvis J, Groppi A, Karkar S, Meiqari L, Rujano MA, Canham S, Dienstmann R, Fijneman R, Hovig E, Meijer G, Nikolski M (2026)
   TrialMatchAI: an end-to-end AI-powered clinical trial recommendation system to streamline patient-to-trial matching
   Nat Commun (in press)
   DOI 10.1038/s41467-026-70509-w, PubMed 41876500
2. Chica N, Andersen AN, Orellana-Muñoz S, Garcia I, P AN, Nakken S, Ayuda-Durán P, Håkensbakken L, Schultz SW, Rødningen E, Putnam CD, Zucknick M, Rusten TE, Enserink JM (2026)
   Time-resolved functional genomics using deep learning reveals global hierarchical control of autophagy
   Nat Cell Biol, 28 (3), 465-479
   DOI 10.1038/s41556-025-01837-0, PubMed 41826700
3. Ekstrøm PO, Nakken S, Hovig E (2026)
   Exploring Taq polymerase induced mutations in part of BRAF exon 15 by sequencing and mutation enrichment
   Mutat Res, 832, 111934 (in press)
   DOI 10.1016/j.mrfmmm.2026.111934, PubMed 41905007

Publications 2025

1. Bope CD, Kalyanasundaram S, Rand KD, Nakken S, Lingjærde OC, Hovig E (2025)
   StarSignDNA: mutation-to-signature attribution for accurate representation of mutational processes in low-mutation contexts
   NAR Genom Bioinform, 7 (4), lqaf181
   DOI 10.1093/nargab/lqaf181, PubMed 41415301
2. Bouska A, Zhang W, Sharma S, Holte H, Shah RA, Lone WG, Soma MA, Yang R, Liu X, Mehmood S, Chawla RS, Cappelli LV, Fiore D, Gong Q, Heavican-Foral TB, Cannatella JJ, Amador C, Arif A, Smith LM, Lim ST, Ong CK, Feldman AL, Du MQ, Perry AM, de Leval L et al. (2025)
   Integrative Genomic and Transcriptomic Analysis Reveals Targetable Vulnerabilities in Angioimmunoblastic T-Cell Lymphoma
   Am J Hematol, 100 (9), 1486-1501
   DOI 10.1002/ajh.27736, PubMed 40510016
3. Lapão A, Johnson LS, Trachsel-Moncho L, Rodgers SJ, Singh S, Ng MYW, Nakken S, Eskelinen EL, Simonsen A (2025)
   The RAB27A effector SYTL5 regulates mitophagy and mitochondrial metabolism
   Elife, 14
   DOI 10.7554/eLife.105541, PubMed 41294009
4. Zhao S, Nakken S, Vodak D, Hovig E (2025)
   FuSViz-visualization and interpretation of structural variation using cancer genomics and transcriptomics data
   Nucleic Acids Res, 53 (4)
   DOI 10.1093/nar/gkaf078, PubMed 39995037

Publications 2024

1. Bai B, Wise JF, Vodák D, Nakken S, Sharma A, Blaker YN, Brodtkorb M, Hilden V, Trøen G, Ren W, Lorenz S, Lawrence MS, Myklebost O, Kimby E, Pan-Hammarström Q, Steen CB, Meza-Zepeda LA, Beiske K, Smeland EB, Hovig E, Lingjærde OC, Holte H, Myklebust JH (2024)
   Multi-omics profiling of longitudinal samples reveals early genomic changes in follicular lymphoma
   Blood Cancer J, 14 (1), 147
   DOI 10.1038/s41408-024-01124-5, PubMed 39191762
2. Egeland EV, Seip K, Skourti E, Øy GF, Pettersen SJ, Pandya AD, Dahle MA, Haugen MH, Kristian A, Nakken S, Engebraaten O, Mælandsmo GM, Prasmickaite L (2024)
   The SRC-family serves as a therapeutic target in triple negative breast cancer with acquired resistance to chemotherapy
   Br J Cancer, 131 (10), 1656-1667
   DOI 10.1038/s41416-024-02875-5, PubMed 39390250
3. Federico L, Malone B, Tennøe S, Chaban V, Osen JR, Gainullin M, Smorodina E, Kared H, Akbar R, Greiff V, Stratford R, Clancy T, Munthe LA (2024)
   Corrigendum: Experimental validation of immunogenic SARS-CoV-2 T cell epitopes identified by artificial intelligence
   Front Immunol, 15, 1377041
   DOI 10.3389/fimmu.2024.1377041, PubMed 38449865
4. Gainullin M, Federico L, Røkke Osen J, Chaban V, Kared H, Alirezaylavasani A, Lund-Johansen F, Wildendahl G, Jacobsen JA, Sarwar Anjum H, Stratford R, Tennøe S, Malone B, Clancy T, Vaage JT, Henriksen K, Wüsthoff L, Munthe LA (2024)
   People who use drugs show no increase in pre-existing T-cell cross-reactivity toward SARS-CoV-2 but develop a normal polyfunctional T-cell response after standard mRNA vaccination
   Front Immunol, 14, 1235210
   DOI 10.3389/fimmu.2023.1235210, PubMed 38299149
5. Netskar H, Pfefferle A, Goodridge JP, Sohlberg E, Dufva O, Teichmann SA, Brownlie D, Michaëlsson J, Marquardt N, Clancy T, Horowitz A, Malmberg KJ (2024)
   Pan-cancer profiling of tumor-infiltrating natural killer cells through transcriptional reference mapping
   Nat Immunol, 25 (8), 1445-1459
   DOI 10.1038/s41590-024-01884-z, PubMed 38956379
6. Sugita Y, Muraoka D, Demachi-Okamura A, Komuro H, Masago K, Sasaki E, Fukushima Y, Matsui T, Shinohara S, Takahashi Y, Nishida R, Takashima C, Yamaguchi T, Horio Y, Hashimoto K, Tanaka I, Hamana H, Kishi H, Miura D, Tanaka Y, Onoue K, Onoguchi K, Yamashita Y, Stratford R, Clancy T et al. (2024)
   Candidate tumor-specific CD8⁺ T cell subsets identified in the malignant pleural effusion of advanced lung cancer patients by single-cell analysis
   Oncoimmunology, 13 (1), 2371556
   DOI 10.1080/2162402X.2024.2371556, PubMed 38952674
7. Sverchkova A, Burkholz S, Rubsamen R, Stratford R, Clancy T (2024)
   Integrative HLA typing of tumor and adjacent normal tissue can reveal insights into the tumor immune response
   BMC Med Genomics, 17 (1), 37
   DOI 10.1186/s12920-024-01808-8, PubMed 38281021
8. Vardaxis I, Simovski B, Anzar I, Stratford R, Clancy T (2024)
   Deep learning of antibody epitopes using positional permutation vectors
   Comput Struct Biotechnol J, 23, 2695-2707
   DOI 10.1016/j.csbj.2024.06.005, PubMed 39035832

Publications 2023

1. Anzar I, Malone B, Samarakoon P, Vardaxis I, Simovski B, Fontenelle H, Meza-Zepeda LA, Stratford R, Keung EZ, Burgess M, Tawbi HA, Myklebost O, Clancy T (2023)
   The interplay between neoantigens and immune cells in sarcomas treated with checkpoint inhibition
   Front Immunol, 14, 1226445
   DOI 10.3389/fimmu.2023.1226445, PubMed 37799721
2. Chen Z, Zhang B, Guo H, Emani P, Clancy T, Jiang C, Gerstein M, Ning X, Cheng C, Min MR (2023)
   Binding peptide generation for MHC Class I proteins with deep reinforcement learning
   Bioinformatics, 39 (2)
   DOI 10.1093/bioinformatics/btad055, PubMed 36692135
3. Dominguez-Valentin M, Haupt S, Seppälä TT, Sampson JR, Sunde L, Bernstein I, Jenkins MA, Engel C, Aretz S, Nielsen M, Capella G, Balaguer F, Evans DG, Burn J, Holinski-Feder E, Bertario L, Bonanni B, Lindblom A, Levi Z, Macrae F, Winship I, Plazzer JP, Sijmons R, Laghi L, Della Valle A et al. (2023)
   Mortality by age, gene and gender in carriers of pathogenic mismatch repair gene variants receiving surveillance for early cancer diagnosis and treatment: a report from the prospective Lynch syndrome database
   EClinicalMedicine, 58, 101909
   DOI 10.1016/j.eclinm.2023.101909, PubMed 37181409
4. Ellingsen EB, O'Day S, Mezheyeuski A, Gromadka A, Clancy T, Kristedja TS, Milhem M, Zakharia Y (2023)
   Clinical Activity of Combined Telomerase Vaccination and Pembrolizumab in Advanced Melanoma: Results from a Phase I Trial
   Clin Cancer Res, 29 (16), 3026-3036
   DOI 10.1158/1078-0432.CCR-23-0416, PubMed 37378632
5. Federico L, Malone B, Tennøe S, Chaban V, Osen JR, Gainullin M, Smorodina E, Kared H, Akbar R, Greiff V, Stratford R, Clancy T, Munthe LA (2023)
   Experimental validation of immunogenic SARS-CoV-2 T cell epitopes identified by artificial intelligence
   Front Immunol, 14, 1265044
   DOI 10.3389/fimmu.2023.1265044, PubMed 38045681
6. Federico L, Tvedt THA, Gainullin M, Osen JR, Chaban V, Lund KP, Tietze L, Tran TT, Lund-Johansen F, Kared H, Lind A, Vaage JT, Stratford R, Tennøe S, Malone B, Clancy T, Myhre AEL, Gedde-Dahl T, Munthe LA (2023)
   Robust spike-specific CD4⁺ and CD8⁺ T cell responses in SARS-CoV-2 vaccinated hematopoietic cell transplantation recipients: a prospective, cohort study
   Front Immunol, 14, 1210899
   DOI 10.3389/fimmu.2023.1210899, PubMed 37503339
7. Hanes R, Ayuda-Durán P, Rønneberg L, Nakken S, Hovig E, Zucknick M, Enserink JM (2023)
   screenwerk: a modular tool for the design and analysis of drug combination screens
   Bioinformatics, 39 (1)
   DOI 10.1093/bioinformatics/btac840, PubMed 36573326
8. Komuro H, Shinohara S, Fukushima Y, Demachi-Okamura A, Muraoka D, Masago K, Matsui T, Sugita Y, Takahashi Y, Nishida R, Takashima C, Ohki T, Shigematsu Y, Watanabe F, Adachi K, Fukuyama T, Hamana H, Kishi H, Miura D, Tanaka Y, Onoue K, Onoguchi K, Yamashita Y, Stratford R, Clancy T et al. (2023)
   Single-cell sequencing on CD8⁺ TILs revealed the nature of exhausted T cells recognizing neoantigen and cancer/testis antigen in non-small cell lung cancer
   J Immunother Cancer, 11 (8)
   DOI 10.1136/jitc-2023-007180, PubMed 37544663
9. Møller P, Seppälä TT, Ahadova A, Crosbie EJ, Holinski-Feder E, Scott R, Haupt S, Möslein G, Winship I, Broeke SWB, Kohut KE, Ryan N, Bauerfeind P, Thomas LE, Evans DG, Aretz S, Sijmons RH, Half E, Heinimann K, Horisberger K, Monahan K, Engel C, Cavestro GM, Fruscio R, Abu-Freha N et al. (2023)
   Dominantly inherited micro-satellite instable cancer - the four Lynch syndromes - an EHTG, PLSD position statement
   Hered Cancer Clin Pract, 21 (1), 19
   DOI 10.1186/s13053-023-00263-3, PubMed 37821984
10. Nakken S, Gundersen S, Bernal FLM, Polychronopoulos D, Hovig E, Wesche J (2023)
    Comprehensive interrogation of gene lists from genome-scale cancer screens with oncoEnrichR
    Int J Cancer, 153 (10), 1819-1828
    DOI 10.1002/ijc.34666, PubMed 37551617
11. Namløs HM, Khelik K, Nakken S, Vodák D, Hovig E, Myklebost O, Boye K, Meza-Zepeda LA (2023)
    Chromosomal instability and a deregulated cell cycle are intrinsic features of high-risk gastrointestinal stromal tumours with a metastatic potential
    Mol Oncol, 17 (11), 2432-2450
    DOI 10.1002/1878-0261.13514, PubMed 37622176
12. Nielsen M, Monberg T, Sundvold V, Albieri B, Hovgaard D, Petersen MM, Krarup-Hansen A, Met Ö, Camilio K, Clancy T, Stratford R, Sveinbjornsson B, Rekdal Ø, Junker N, Svane IM (2023)
    LTX-315 and adoptive cell therapy using tumor-infiltrating lymphocytes generate tumor specific T cells in patients with metastatic soft tissue sarcoma
    Oncoimmunology, 13 (1), 2290900
    DOI 10.1080/2162402X.2023.2290900, PubMed 38125722
13. Połeć A, Ekstrøm PO, Fougner C, Sørlie T, Norum JH (2023)
    Rapid assessment of 3-dimensional intra-tumor heterogeneity through cycling temperature capillary electrophoresis
    BMC Res Notes, 16 (1), 167
    DOI 10.1186/s13104-023-06437-5, PubMed 37568187

Publications 2022

1. Anzar I, Sverchkova A, Samarakoon P, Ellingsen EB, Gaudernack G, Stratford R, Clancy T (2022)
   Personalized HLA typing leads to the discovery of novel HLA alleles and tumor-specific HLA variants
   HLA, 99 (4), 313-327
   DOI 10.1111/tan.14562, PubMed 35073457
2. Ellingsen EB, Bounova G, Kerzeli I, Anzar I, Simnica D, Aamdal E, Guren T, Clancy T, Mezheyeuski A, Inderberg EM, Mangsbo SM, Binder M, Hovig E, Gaudernack G (2022)
   Characterization of the T cell receptor repertoire and melanoma tumor microenvironment upon combined treatment with ipilimumab and hTERT vaccination
   J Transl Med, 20 (1), 419
   DOI 10.1186/s12967-022-03624-z, PubMed 36089578
3. Fiorito E, Szybowska P, Haugsten EM, Kostas M, Øy GF, Wiedlocha A, Singh S, Nakken S, Mælandsmo GM, Fletcher JA, Meza-Zepeda LA, Wesche J (2022)
   Strategies to inhibit FGFR4 V550L-driven rhabdomyosarcoma
   Br J Cancer, 127 (11), 1939-1953
   DOI 10.1038/s41416-022-01973-6, PubMed 36097178
4. Giliberto M, Santana LM, Holien T, Misund K, Nakken S, Vodak D, Hovig E, Meza-Zepeda LA, Coward E, Waage A, Taskén K, Skånland SS (2022)
   Mutational analysis and protein profiling predict drug sensitivity in multiple myeloma cell lines
   Front Oncol, 12, 1040730
   DOI 10.3389/fonc.2022.1040730, PubMed 36523963
5. Møller P, Seppälä T, Dowty JG, Haupt S, Dominguez-Valentin M, Sunde L, Bernstein I, Engel C, Aretz S, Nielsen M, Capella G, Evans DG, Burn J, Holinski-Feder E, Bertario L, Bonanni B, Lindblom A, Levi Z, Macrae F, Winship I, Plazzer JP, Sijmons R, Laghi L, Valle AD, Heinimann K et al. (2022)
   Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium
   Hered Cancer Clin Pract, 20 (1), 36
   DOI 10.1186/s13053-022-00241-1, PubMed 36182917
6. Ng MYW, Charsou C, Lapao A, Singh S, Trachsel-Moncho L, Schultz SW, Nakken S, Munson MJ, Simonsen A (2022)
   The cholesterol transport protein GRAMD1C regulates autophagy initiation and mitochondrial bioenergetics
   Nat Commun, 13 (1), 6283
   DOI 10.1038/s41467-022-33933-2, PubMed 36270994
7. Tennøe S, Gheorghe M, Stratford R, Clancy T (2022)
   The T Cell Epitope Landscape of SARS-CoV-2 Variants of Concern
   Vaccines (Basel), 10 (7)
   DOI 10.3390/vaccines10071123, PubMed 35891287
8. Venizelos A, Engebrethsen C, Deng W, Geisler J, Geisler S, Iversen GT, Aas T, Aase HS, Seyedzadeh M, Steinskog ES, Myklebost O, Nakken S, Vodak D, Hovig E, Meza-Zepeda LA, Lønning PE, Knappskog S, Eikesdal HP (2022)
   Clonal evolution in primary breast cancers under sequential epirubicin and docetaxel monotherapy
   Genome Med, 14 (1), 86
   DOI 10.1186/s13073-022-01090-2, PubMed 35948919
9. Zavaleta E, Solis N, Palacios MI, Zevallos-Escobar LE, Corales EV, Bazo-Alvarez JC, Dominguez-Barrera C, Campos A, Wernhoff P, Ekstrøm PO, Møller P, Visnovska T, Hovig E, Balazar-Palacios J, Alvarez-Valenzuela K, Nakken S, Dominguez-Valentin M (2022)
   Genetic Characterization in High-Risk Individuals from a Low-Resource City of Peru
   Cancers (Basel), 14 (22)
   DOI 10.3390/cancers14225603, PubMed 36428697

Publications 2021

1. Dominguez-Valentin M, Plazzer JP, Sampson JR, Engel C, Aretz S, Jenkins MA, Sunde L, Bernstein I, Capella G, Balaguer F, Macrae F, Winship IM, Thomas H, Evans DG, Burn J, Greenblatt M, de Vos Tot Nederveen Cappel WH, Sijmons RH, Nielsen M, Bertario L, Bonanni B, Tibiletti MG, Cavestro GM, Lindblom A, Valle AD et al. (2021)
   No Difference in Penetrance between Truncating and Missense/Aberrant Splicing Pathogenic Variants in MLH1 and MSH2: A Prospective Lynch Syndrome Database Study
   J Clin Med, 10 (13)
   DOI 10.3390/jcm10132856, PubMed 34203177
2. Nakken S, Lilleby W, Switlyk MD, Knudsen KE, Lilleby O, Zhao S, Kaveh F, Ekstrøm PO, Urbanucci A, Hovig E (2021)
   The Quandary of DNA-Based Treatment Assessment in De Novo Metastatic Prostate Cancer in the Era of Precision Oncology
   J Pers Med, 11 (5)
   DOI 10.3390/jpm11050330, PubMed 33922147
3. Nakken S, Saveliev V, Hofmann O, Møller P, Myklebost O, Hovig E (2021)
   Cancer Predisposition Sequencing Reporter (CPSR): A flexible variant report engine for high-throughput germline screening in cancer
   Int J Cancer, 149 (11), 1955-1960
   DOI 10.1002/ijc.33749, PubMed 34310709
4. Aamdal E, Inderberg EM, Ellingsen EB, Rasch W, Brunsvig PF, Aamdal S, Heintz KM, Vodák D, Nakken S, Hovig E, Nyakas M, Guren TK, Gaudernack G (2021)
   Combining a Universal Telomerase Based Cancer Vaccine With Ipilimumab in Patients With Metastatic Melanoma - Five-Year Follow Up of a Phase I/IIa Trial
   Front Immunol, 12, 663865
   DOI 10.3389/fimmu.2021.663865, PubMed 34046035

Publications 2020

1. Arstad C, Taskén K, Refinetti P, Axcrona U, Giercksky KE, Ekstrøm PO (2020)
   Somatic Mitochondrial DNA Point Mutations Used as Biomarkers to Demonstrate Genomic Heterogeneity in Primary Prostate Cancer
   Prostate Cancer, 2020, 7673684
   DOI 10.1155/2020/7673684, PubMed 32908706
2. Dominguez-Valentin M, Crosbie EJ, Engel C, Aretz S, Macrae F, Winship I, Capella G, Thomas H, Nakken S, Hovig E, Nielsen M, Sijmons RH, Bertario L, Bonanni B, Tibiletti MG, Cavestro GM, Mints M, Gluck N, Katz L, Heinimann K, Vaccaro CA, Green K, Lalloo F, Hill J, Schmiegel W et al. (2020)
   Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report
   Genet Med, 23 (4), 705-712
   DOI 10.1038/s41436-020-01029-1, PubMed 33257847
3. Dominguez-Valentin M, Sampson JR, Seppälä TT, Ten Broeke SW, Plazzer JP, Nakken S, Engel C, Aretz S, Jenkins MA, Sunde L, Bernstein I, Capella G, Balaguer F, Thomas H, Evans DG, Burn J, Greenblatt M, Hovig E, de Vos Tot Nederveen Cappel WH, Sijmons RH, Bertario L, Tibiletti MG, Cavestro GM, Lindblom A, Della Valle A et al. (2020)
   Correction: Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database
   Genet Med, 22 (9), 1569
   DOI 10.1038/s41436-020-0892-4, PubMed 32690931
4. Lavelle TJ, Alver TN, Heintz KM, Wernhoff P, Nygaard V, Nakken S, Øy GF, Bøe SL, Urbanucci A, Hovig E (2020)
   Dysregulation of MITF Leads to Transformation in MC1R-Defective Melanocytes
   Cancers (Basel), 12 (7)
   DOI 10.3390/cancers12071719, PubMed 32605315
5. Malone B, Simovski B, Moliné C, Cheng J, Gheorghe M, Fontenelle H, Vardaxis I, Tennøe S, Malmberg JA, Stratford R, Clancy T (2020)
   Artificial intelligence predicts the immunogenic landscape of SARS-CoV-2 leading to universal blueprints for vaccine designs
   Sci Rep, 10 (1), 22375
   DOI 10.1038/s41598-020-78758-5, PubMed 33361777
6. Ree AH, Nygaard V, Boye K, Heinrich D, Dueland S, Bergheim IR, Johansen C, Beiske K, Negård A, Lund-Iversen M, Nygaard V, Hovig E, Nakken S, Nasser S, Julsrud L, Reisse CH, Ruud EA, Kristensen VN, Flørenes VA, Geitvik GA, Lingjærde OC, Børresen-Dale AL, Russnes HG, Mælandsmo GM, Flatmark K (2020)
   Molecularly matched therapy in the context of sensitivity, resistance, and safety; patient outcomes in end-stage cancer - the MetAction study
   Acta Oncol, 59 (7), 733-740
   DOI 10.1080/0284186X.2020.1742377, PubMed 32208873
7. Refinetti P, Morgenthaler S, Thilly WG, Arstad C, Ekstrøm PO (2020)
   Tracing of Human Tumor Cell Lineages by Mitochondrial Mutations
   Front Oncol, 10, 523860
   DOI 10.3389/fonc.2020.523860, PubMed 33344219
8. Wise JF, Nakken S, Steen CB, Vodák D, Trøen G, Johannessen B, Lingjærde OC, Hilden V, Blaker YN, Bai B, Aasheim LB, Pasanen A, Lorenz S, Sveen A, Lothe RA, Myklebost O, Leppä S, Meza-Zepeda LA, Beiske K, Lawrence MS, Hovig E, Myklebust JH, Smeland EB, Holte H (2020)
   Mutational dynamics and immune evasion in diffuse large B-cell lymphoma explored in a relapse-enriched patient series
   Blood Adv, 4 (9), 1859-1866
   DOI 10.1182/bloodadvances.2019001325, PubMed 32374878

Publications 2019

1. Anzar I, Sverchkova A, Stratford R, Clancy T (2019)
   NeoMutate: an ensemble machine learning framework for the prediction of somatic mutations in cancer
   BMC Med Genomics, 12 (1), 63
   DOI 10.1186/s12920-019-0508-5, PubMed 31096972
2. Dominguez-Valentin M, Nakken S, Tubeuf H, Vodak D, Ekstrøm PO, Nissen AM, Morak M, Holinski-Feder E, Holth A, Capella G, Davidson B, Evans DG, Martins A, Møller P, Hovig E (2019)
   Results of multigene panel testing in familial cancer cases without genetic cause demonstrated by single gene testing
   Sci Rep, 9 (1), 18555
   DOI 10.1038/s41598-019-54517-z, PubMed 31811167
3. Dominguez-Valentin M, Sampson JR, Seppälä TT, Ten Broeke SW, Plazzer JP, Nakken S, Engel C, Aretz S, Jenkins MA, Sunde L, Bernstein I, Capella G, Balaguer F, Thomas H, Evans DG, Burn J, Greenblatt M, Hovig E, de Vos Tot Nederveen Cappel WH, Sijmons RH, Bertario L, Tibiletti MG, Cavestro GM, Lindblom A, Della Valle A et al. (2019)
   Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database
   Genet Med, 22 (1), 15-25
   DOI 10.1038/s41436-019-0596-9, PubMed 31337882
4. Dominguez-Valentin M, Seppälä TT, Sampson JR, Macrae F, Winship I, Evans DG, Scott RJ, Burn J, Möslein G, Bernstein I, Pylvänäinen K, Renkonen-Sinisalo L, Lepistö A, Lindblom A, Plazzer JP, Tjandra D, Thomas H, Green K, Lalloo F, Crosbie EJ, Hill J, Capella G, Pineda M, Navarro M, Vidal JB et al. (2019)
   Survival by colon cancer stage and screening interval in Lynch syndrome: a prospective Lynch syndrome database report
   Hered Cancer Clin Pract, 17, 28
   DOI 10.1186/s13053-019-0127-3, PubMed 31636762
5. Goodridge JP, Jacobs B, Saetersmoen ML, Clement D, Hammer Q, Clancy T, Skarpen E, Brech A, Landskron J, Grimm C, Pfefferle A, Meza-Zepeda L, Lorenz S, Wiiger MT, Louch WE, Ask EH, Liu LL, Oei VYS, Kjällquist U, Linnarsson S, Patel S, Taskén K, Stenmark H, Malmberg KJ (2019)
   Remodeling of secretory lysosomes during education tunes functional potential in NK cells
   Nat Commun, 10 (1), 514
   DOI 10.1038/s41467-019-08384-x, PubMed 30705279
6. Lund-Andersen C, Nakken S, Nygård S, Fromm B, Aasheim LB, Davidson B, Julsrud L, Abrahamsen TW, Kristensen AT, Dybdahl B, Larsen SG, Hovig E, Flatmark K (2019)
   Integrative genomic analysis of peritoneal malignant mesothelioma: understanding a case with extraordinary chemotherapy response
   Cold Spring Harb Mol Case Stud, 5 (2)
   DOI 10.1101/mcs.a003566, PubMed 30862609
7. Pfefferle A, Jacobs B, Netskar H, Ask EH, Lorenz S, Clancy T, Goodridge JP, Sohlberg E, Malmberg KJ (2019)
   Intra-lineage Plasticity and Functional Reprogramming Maintain Natural Killer Cell Repertoire Diversity
   Cell Rep, 29 (8), 2284-2294.e4
   DOI 10.1016/j.celrep.2019.10.058, PubMed 31747601
8. Seppälä TT, Ahadova A, Dominguez-Valentin M, Macrae F, Evans DG, Therkildsen C, Sampson J, Scott R, Burn J, Möslein G, Bernstein I, Holinski-Feder E, Pylvänäinen K, Renkonen-Sinisalo L, Lepistö A, Lautrup CK, Lindblom A, Plazzer JP, Winship I, Tjandra D, Katz LH, Aretz S, Hüneburg R, Holzapfel S, Heinimann K et al. (2019)
   Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; a prospective Lynch syndrome database report
   Hered Cancer Clin Pract, 17, 8
   DOI 10.1186/s13053-019-0106-8, PubMed 30858900
9. Sverchkova A, Anzar I, Stratford R, Clancy T (2019)
   Improved HLA typing of Class I and Class II alleles from next-generation sequencing data
   HLA, 94 (6), 504-513
   DOI 10.1111/tan.13685, PubMed 31496113

Publications 2018

1. Birkeland E, Zhang S, Poduval D, Geisler J, Nakken S, Vodak D, Meza-Zepeda LA, Hovig E, Myklebost O, Knappskog S, Lønning PE (2018)
   Patterns of genomic evolution in advanced melanoma
   Nat Commun, 9 (1), 2665
   DOI 10.1038/s41467-018-05063-1, PubMed 29991680
2. Björklund AT, Carlsten M, Sohlberg E, Liu LL, Clancy T, Karimi M, Cooley S, Miller JS, Klimkowska M, Schaffer M, Watz E, Wikström K, Blomberg P, Wahlin BE, Palma M, Hansson L, Ljungman P, Hellström-Lindberg E, Ljunggren HG, Malmberg KJ (2018)
   Complete Remission with Reduction of High-Risk Clones following Haploidentical NK-Cell Therapy against MDS and AML
   Clin Cancer Res, 24 (8), 1834-1844
   DOI 10.1158/1078-0432.CCR-17-3196, PubMed 29444931
3. Dominguez-Valentin M, Evans DGR, Nakken S, Tubeuf H, Vodak D, Ekstrøm PO, Nissen AM, Morak M, Holinski-Feder E, Martins A, Møller P, Hovig E (2018)
   Genetic variants of prospectively demonstrated phenocopies in BRCA1/2 kindreds
   Hered Cancer Clin Pract, 16, 4
   DOI 10.1186/s13053-018-0086-0, PubMed 29371908
4. Dominguez-Valentin M, Nakken S, Tubeuf H, Vodak D, Ekstrøm PO, Nissen AM, Morak M, Holinski-Feder E, Martins A, Møller P, Hovig E (2018)
   Potentially pathogenic germline CHEK2 c.319+2T>A among multiple early-onset cancer families
   Fam Cancer, 17 (1), 141-153
   DOI 10.1007/s10689-017-0011-0, PubMed 28608266
5. Dominguez-Valentin M, Nakken S, Tubeuf H, Vodak D, Ekstrøm PO, Nissen AM, Morak M, Holinski-Feder E, Martins A, Møller P, Hovig E (2018)
   Identification of genetic variants for clinical management of familial colorectal tumors
   BMC Med Genet, 19 (1), 26
   DOI 10.1186/s12881-018-0533-9, PubMed 29458332
6. Nakken S, Fournous G, Vodák D, Aasheim LB, Myklebost O, Hovig E (2018)
   Personal Cancer Genome Reporter: variant interpretation report for precision oncology
   Bioinformatics, 34 (10), 1778-1780
   DOI 10.1093/bioinformatics/btx817, PubMed 29272339
7. Tutturen AEV, Dørum S, Clancy T, Reims HM, Christophersen A, Lundin KEA, Sollid LM, de Souza GA, Stamnaes J (2018)
   Characterization of the Small Intestinal Lesion in Celiac Disease by Label-Free Quantitative Mass Spectrometry
   Am J Pathol, 188 (7), 1563-1579
   DOI 10.1016/j.ajpath.2018.03.017, PubMed 29684362
8. Vodák D, Lorenz S, Nakken S, Aasheim LB, Holte H, Bai B, Myklebost O, Meza-Zepeda LA, Hovig E (2018)
   Sample-Index Misassignment Impacts Tumour Exome Sequencing
   Sci Rep, 8 (1), 5307
   DOI 10.1038/s41598-018-23563-4, PubMed 29593270

Publications 2017

1. Arstad C, Refinetti P, Kristensen AT, Giercksky KE, Ekstrøm PO (2017)
   Is detection of intraperitoneal exfoliated tumor cells after surgical resection of rectal cancer a prognostic factor of survival?
   BMC Cancer, 17 (1), 406
   DOI 10.1186/s12885-017-3365-7, PubMed 28592327
2. Clancy T, Dannenfelser R, Troyanskaya O, Malmberg KJ, Hovig E, Kristensen V (2017)
   Bioinformatics Approaches to Profile the Tumor Microenvironment for Immunotherapeutic Discovery
   Curr Pharm Des, 23 (32), 4716-4725
   DOI 10.2174/1381612823666170710154936, PubMed 28699527
3. Helland Å, Brustugun OT, Nakken S, Halvorsen AR, Dønnem T, Bremnes R, Busund LT, Sun J, Lorenz S, Solberg SK, Jørgensen LH, Vodak D, Myklebost O, Hovig E, Meza-Zepeda LA (2017)
   High number of kinome-mutations in non-small cell lung cancer is associated with reduced immune response and poor relapse-free survival
   Int J Cancer, 141 (1), 184-190
   DOI 10.1002/ijc.30726, PubMed 28387924
4. Møller P, Seppälä TT, Bernstein I, Holinski-Feder E, Sala P, Gareth Evans D, Lindblom A, Macrae F, Blanco I, Sijmons RH, Jeffries J, Vasen HFA, Burn J, Nakken S, Hovig E, Rødland EA, Tharmaratnam K, de Vos Tot Nederveen Cappel WH, Hill J, Wijnen JT, Jenkins MA, Green K, Lalloo F, Sunde L, Mints M et al. (2017)
   Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database
   Gut, 67 (7), 1306-1316
   DOI 10.1136/gutjnl-2017-314057, PubMed 28754778
5. Ree AH, Russnes HG, Heinrich D, Dueland S, Boye K, Nygaard V, Silwal-Pandit L, Østrup O, Hovig E, Nygaard V, Rødland EA, Nakken S, Øien JT, Johansen C, Bergheim IR, Skarpeteig V, Sathermugathevan M, Sauer T, Lund-Iversen M, Beiske K, Nasser S, Julsrud L, Reisse CH, Ruud EA, Flørenes VA et al. (2017)
   Implementing precision cancer medicine in the public health services of Norway: the diagnostic infrastructure and a cost estimate
   ESMO Open, 2 (2), e000158
   DOI 10.1136/esmoopen-2017-000158, PubMed 28761742
6. Refinetti P, Arstad C, Thilly WG, Morgenthaler S, Ekstrøm PO (2017)
   Mapping mitochondrial heteroplasmy in a Leydig tumor by laser capture micro-dissection and cycling temperature capillary electrophoresis
   BMC Clin Pathol, 17, 6
   DOI 10.1186/s12907-017-0042-3, PubMed 28405177
7. Refinetti P, Warren D, Morgenthaler S, Ekstrøm PO (2017)
   Quantifying mitochondrial DNA copy number using robust regression to interpret real time PCR results
   BMC Res Notes, 10 (1), 593
   DOI 10.1186/s13104-017-2913-1, PubMed 29132417
8. Seppälä T, Pylvänäinen K, Evans DG, Järvinen H, Renkonen-Sinisalo L, Bernstein I, Holinski-Feder E, Sala P, Lindblom A, Macrae F, Blanco I, Sijmons R, Jeffries J, Vasen H, Burn J, Nakken S, Hovig E, Rødland EA, Tharmaratnam K, de Vos Tot Nederveen Cappel WH, Hill J, Wijnen J, Jenkins M, Genuardi M, Green K et al. (2017)
   Colorectal cancer incidence in path_MLH1 carriers subjected to different follow-up protocols: a Prospective Lynch Syndrome Database report
   Hered Cancer Clin Pract, 15, 18
   DOI 10.1186/s13053-017-0078-5, PubMed 29046738
9. Simovski B, Vodák D, Gundersen S, Domanska D, Azab A, Holden L, Holden M, Grytten I, Rand K, Drabløs F, Johansen M, Mora A, Lund-Andersen C, Fromm B, Eskeland R, Gabrielsen OS, Ferkingstad E, Nakken S, Bengtsen M, Nederbragt AJ, Thorarensen HS, Akse JA, Glad I, Hovig E, Sandve GK (2017)
   GSuite HyperBrowser: integrative analysis of dataset collections across the genome and epigenome
   Gigascience, 6 (7), 1-12
   DOI 10.1093/gigascience/gix032, PubMed 28459977

Publications 2016

1. Arstad C, Refinetti P, Warren D, Giercksky KE, Ekstrøm PO (2016)
   Scanning the mitochondrial genome for mutations by cycling temperature capillary electrophoresis
   Mitochondrial DNA A DNA Mapp Seq Anal, 29 (1), 19-30
   DOI 10.1080/24701394.2016.1233532, PubMed 27728990
2. Björklund AT, Clancy T, Goodridge JP, Béziat V, Schaffer M, Hovig E, Ljunggren HG, Ljungman PT, Malmberg KJ (2016)
   Naive Donor NK Cell Repertoires Associated with Less Leukemia Relapse after Allogeneic Hematopoietic Stem Cell Transplantation
   J Immunol, 196 (3), 1400-11
   DOI 10.4049/jimmunol.1501434, PubMed 26746188
3. Clancy T, Hovig E (2016)
   Profiling networks of distinct immune-cells in tumors
   BMC Bioinformatics, 17 (1), 263
   DOI 10.1186/s12859-016-1141-3, PubMed 27377892
4. Jonsson M, Ragnum HB, Julin CH, Yeramian A, Clancy T, Frikstad KM, Seierstad T, Stokke T, Matias-Guiu X, Ree AH, Flatmark K, Lyng H (2016)
   Hypoxia-independent gene expression signature associated with radiosensitisation of prostate cancer cell lines by histone deacetylase inhibition
   Br J Cancer, 115 (8), 929-939
   DOI 10.1038/bjc.2016.278, PubMed 27599042
5. Joshi S, Schjølberg AR, Ekstrøm PO, De Angelis PM, Zucknick M, Andersen SN, Clausen OP (2016)
   Tp53/p53 status in keratoacanthomas
   J Cutan Pathol, 43 (7), 571-8
   DOI 10.1111/cup.12713, PubMed 27020606
6. Landfors M, Nakken S, Fusser M, Dahl JA, Klungland A, Fedorcsak P (2016)
   Sequencing of FTO and ALKBH5 in men undergoing infertility work-up identifies an infertility-associated variant and two missense mutations
   Fertil Steril, 105 (5), 1170-1179.e5
   DOI 10.1016/j.fertnstert.2016.01.002, PubMed 26820768
7. Møller P, Seppälä T, Bernstein I, Holinski-Feder E, Sala P, Evans DG, Lindblom A, Macrae F, Blanco I, Sijmons R, Jeffries J, Vasen H, Burn J, Nakken S, Hovig E, Rødland EA, Tharmaratnam K, de Vos Tot Nederveen Cappel WH, Hill J, Wijnen J, Jenkins M, Green K, Lalloo F, Sunde L, Mints M et al. (2016)
   Incidence of and survival after subsequent cancers in carriers of pathogenic MMR variants with previous cancer: a report from the prospective Lynch syndrome database
   Gut, 66 (9), 1657-1664
   DOI 10.1136/gutjnl-2016-311403, PubMed 27261338
8. Refinetti P, Morgenthaler S, Ekstrøm PO (2016)
   Cycling temperature capillary electrophoresis: A quantitative, fast and inexpensive method to detect mutations in mixed populations of human mitochondrial DNA
   Mitochondrion, 29, 65-74
   DOI 10.1016/j.mito.2016.04.006, PubMed 27166160

Publications 2015

1. Alioto TS, Buchhalter I, Derdak S, Hutter B, Eldridge MD, Hovig E, Heisler LE, Beck TA, Simpson JT, Tonon L, Sertier AS, Patch AM, Jäger N, Ginsbach P, Drews R, Paramasivam N, Kabbe R, Chotewutmontri S, Diessl N, Previti C, Schmidt S, Brors B, Feuerbach L, Heinold M, Gröbner S et al. (2015)
   A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing
   Nat Commun, 6, 10001
   DOI 10.1038/ncomms10001, PubMed 26647970
2. Ekstrøm PO, Nakken S, Johansen M, Hovig E (2015)
   Automated amplicon design suitable for analysis of DNA variants by melting techniques
   BMC Res Notes, 8, 667
   DOI 10.1186/s13104-015-1624-8, PubMed 26559640
3. Heramb C, Ekstrøm PO, Tharmaratnam K, Hovig E, Møller P, Mæhle L (2015)
   Ten modifiers of BRCA1 penetrance validated in a Norwegian series
   Hered Cancer Clin Pract, 13 (1), 14
   DOI 10.1186/s13053-015-0035-0, PubMed 26052370
4. Møller P, Seppälä T, Bernstein I, Holinski-Feder E, Sala P, Evans DG, Lindblom A, Macrae F, Blanco I, Sijmons R, Jeffries J, Vasen H, Burn J, Nakken S, Hovig E, Rødland EA, Tharmaratnam K, de Vos Tot Nederveen Cappel WH, Hill J, Wijnen J, Green K, Lalloo F, Sunde L, Mints M, Bertario L et al. (2015)
   Cancer incidence and survival in Lynch syndrome patients receiving colonoscopic and gynaecological surveillance: first report from the prospective Lynch syndrome database
   Gut, 66 (3), 464-472
   DOI 10.1136/gutjnl-2015-309675, PubMed 26657901
5. Rustad EH, Dai HY, Hov H, Coward E, Beisvag V, Myklebost O, Hovig E, Nakken S, Vodák D, Meza-Zepeda LA, Sandvik AK, Wader KF, Misund K, Sundan A, Aarset H, Waage A (2015)
   BRAF V600E mutation in early-stage multiple myeloma: good response to broad acting drugs and no relation to prognosis
   Blood Cancer J, 5 (3), e299
   DOI 10.1038/bcj.2015.24, PubMed 25794135

Publications 2014

1. Clancy T, Hovig E (2014)
   From proteomes to complexomes in the era of systems biology
   Proteomics, 14 (1), 24-41
   DOI 10.1002/pmic.201300230, PubMed 24243660
2. Clancy T, Hovig E (2014)
   Differential protein network analysis of the immune cell lineage
   Biomed Res Int, 2014, 363408
   DOI 10.1155/2014/363408, PubMed 25309909
3. Friis-Ottessen M, Burum-Auensen E, Schjølberg AR, Ekstrøm PO, Andersen SN, Clausen OP, De Angelis PM (2014)
   TP53/p53 alterations and Aurora A expression in progressor and non-progressor colectomies from patients with longstanding ulcerative colitis
   Int J Mol Med, 35 (1), 24-30
   DOI 10.3892/ijmm.2014.1974, PubMed 25333414
4. Nygård S, Reitan T, Clancy T, Nygaard V, Bjørnstad J, Skrbic B, Tønnessen T, Christensen G, Hovig E (2014)
   Identifying pathogenic processes by integrating microarray data with prior knowledge
   BMC Bioinformatics, 15, 115
   DOI 10.1186/1471-2105-15-115, PubMed 24758699
5. Nygaard V, Prasmickaite L, Vasiliauskaite K, Clancy T, Hovig E (2014)
   Melanoma brain colonization involves the emergence of a brain-adaptive phenotype
   Oncoscience, 1 (1), 82-94
   DOI 10.18632/oncoscience.11, PubMed 25593989

Publications 2013

1. Bettum IJ, Vasiliauskaite K, Nygaard V, Clancy T, Pettersen SJ, Tenstad E, Mælandsmo GM, Prasmickaite L (2013)
   Metastasis-associated protein S100A4 induces a network of inflammatory cytokines that activate stromal cells to acquire pro-tumorigenic properties
   Cancer Lett, 344 (1), 28-39
   DOI 10.1016/j.canlet.2013.10.036, PubMed 24215866
2. Clancy T, Rødland EA, Nygard S, Hovig E (2013)
   Predicting physical interactions between protein complexes
   Mol Cell Proteomics, 12 (6), 1723-34
   DOI 10.1074/mcp.O112.019828, PubMed 23438732
3. Lando M, Wilting SM, Snipstad K, Clancy T, Bierkens M, Aarnes EK, Holden M, Stokke T, Sundfør K, Holm R, Kristensen GB, Steenbergen RD, Lyng H (2013)
   Identification of eight candidate target genes of the recurrent 3p12-p14 loss in cervical cancer by integrative genomic profiling
   J Pathol, 230 (1), 59-69
   DOI 10.1002/path.4168, PubMed 23335387
4. Lorvik KB, Haabeth OA, Clancy T, Bogen B, Corthay A (2013)
   Molecular profiling of tumor-specific T_H1 cells activated in vivo
   Oncoimmunology, 2 (5), e24383
   DOI 10.4161/onci.24383, PubMed 23762808
5. Sandve GK, Gundersen S, Johansen M, Glad IK, Gunathasan K, Holden L, Holden M, Liestøl K, Nygård S, Nygaard V, Paulsen J, Rydbeck H, Trengereid K, Clancy T, Drabløs F, Ferkingstad E, Kalas M, Lien T, Rye MB, Frigessi A, Hovig E (2013)
   The Genomic HyperBrowser: an analysis web server for genome-scale data
   Nucleic Acids Res, 41 (Web Server issue), W133-41
   DOI 10.1093/nar/gkt342, PubMed 23632163
6. Yri OE, Ekstrøm PO, Hilden V, Gaudernack G, Liestøl K, Smeland EB, Holte H (2013)
   Influence of polymorphisms in genes encoding immunoregulatory proteins and metabolizing enzymes on susceptibility and outcome in patients with diffuse large B-cell lymphoma treated with rituximab
   Leuk Lymphoma, 54 (10), 2205-14
   DOI 10.3109/10428194.2013.774392, PubMed 23391141

Publications 2012

1. Ekstrøm PO, Warren DJ, Thilly WG (2012)
   Separation principles of cycling temperature capillary electrophoresis
   Electrophoresis, 33 (7), 1162-8
   DOI 10.1002/elps.201100550, PubMed 22539319
2. Nakken S, Johansen M, Fillebeen J, Berge OP, Kirkerød H, Jenssen TK, Hovig E (2012)
   CellLineMiner: a knowledge portal for human cell lines
   Bioinformation, 8 (22), 1119-22
   DOI 10.6026/97320630081119, PubMed 23251048
3. Yri OE, Ekstrøm PO, Hilden V, Gaudernack G, Liestøl K, Smeland EB, Holte H (2012)
   Polymorphisms in genes encoding interleukin-10 and drug metabolizing enzymes GSTP1, GSTT1, GSTA1 and UGT1A1 influence risk and outcome in Hodgkin lymphoma
   Leuk Lymphoma, 53 (10), 1934-44
   DOI 10.3109/10428194.2012.682307, PubMed 22475179

Publications 2011

1. Clancy T, Pedicini M, Castiglione F, Santoni D, Nygaard V, Lavelle TJ, Benson M, Hovig E (2011)
   Immunological network signatures of cancer progression and survival
   BMC Med Genomics, 4, 28
   DOI 10.1186/1755-8794-4-28, PubMed 21453479
2. Halle C, Lando M, Svendsrud DH, Clancy T, Holden M, Sundfør K, Kristensen GB, Holm R, Lyng H (2011)
   Membranous expression of ectodomain isoforms of the epidermal growth factor receptor predicts outcome after chemoradiotherapy of lymph node-negative cervical cancer
   Clin Cancer Res, 17 (16), 5501-12
   DOI 10.1158/1078-0432.CCR-11-0297, PubMed 21737508
3. Kerty E, Heuser K, Indahl UG, Berg PR, Nakken S, Lien S, Omholt SW, Ottersen OP, Nagelhus EA (2011)
   Is the brain water channel aquaporin-4 a pathogenetic factor in idiopathic intracranial hypertension? Results from a combined clinical and genetic study in a Norwegian cohort
   Acta Ophthalmol, 91 (1), 88-91
   DOI 10.1111/j.1755-3768.2011.02231.x, PubMed 21914143
4. Sandve GK, Gundersen S, Rydbeck H, Glad IK, Holden L, Holden M, Liestøl K, Clancy T, Drabløs F, Ferkingstad E, Johansen M, Nygaard V, Tøstesen E, Frigessi A, Hovig E (2011)
   The differential disease regulome
   BMC Genomics, 12, 353
   DOI 10.1186/1471-2164-12-353, PubMed 21736759
5. Selmer KK, Gilfillan GD, Strømme P, Lyle R, Hughes T, Hjorthaug HS, Brandal K, Nakken S, Misceo D, Egeland T, Munthe LA, Braekken SK, Undlien DE (2011)
   A mild form of Mucopolysaccharidosis IIIB diagnosed with targeted next-generation sequencing of linked genomic regions
   Eur J Hum Genet, 20 (1), 58-63
   DOI 10.1038/ejhg.2011.126, PubMed 21712855
6. Ågesen TH, Berg M, Clancy T, Thiis-Evensen E, Cekaite L, Lind GE, Nesland JM, Bakka A, Mala T, Hauss HJ, Fetveit T, Vatn MH, Hovig E, Nesbakken A, Lothe RA, Skotheim RI (2011)
   CLC and IFNAR1 are differentially expressed and a global immunity score is distinct between early- and late-onset colorectal cancer
   Genes Immun, 12 (8), 653-62
   DOI 10.1038/gene.2011.43, PubMed 21716316

Publications 2010

1. Beck H, Nähse V, Larsen MS, Groth P, Clancy T, Lees M, Jørgensen M, Helleday T, Syljuåsen RG, Sørensen CS (2010)
   Regulators of cyclin-dependent kinases are crucial for maintaining genome integrity in S phase
   J Cell Biol, 188 (5), 629-38
   DOI 10.1083/jcb.200905059, PubMed 20194642
2. Cekaite L, Clancy T, Sioud M (2010)
   Increased miR-21 expression during human monocyte differentiation into DCs
   Front Biosci (Elite Ed), 2 (3), 818-28
   DOI 10.2741/e143, PubMed 20515755
3. Falster DS, Nakken S, Bergem-Ohr M, Rødland EA, Breivik J (2010)
   Unstable DNA repair genes shaped by their own sequence modifying phenotypes
   J Mol Evol, 70 (3), 266-74
   DOI 10.1007/s00239-010-9328-0, PubMed 20213140
4. Nakken S, Rødland EA, Hovig E (2010)
   Impact of DNA physical properties on local sequence bias of human mutation
   Hum Mutat, 31 (12), 1316-25
   DOI 10.1002/humu.21371, PubMed 20886615
5. Pedicini M, Barrenäs F, Clancy T, Castiglione F, Hovig E, Kanduri K, Santoni D, Benson M (2010)
   Combining network modeling and gene expression microarray analysis to explore the dynamics of Th1 and Th2 cell regulation
   PLoS Comput Biol, 6 (12), e1001032
   DOI 10.1371/journal.pcbi.1001032, PubMed 21187905
6. Sandve GK, Gundersen S, Rydbeck H, Glad IK, Holden L, Holden M, Liestøl K, Clancy T, Ferkingstad E, Johansen M, Nygaard V, Tøstesen E, Frigessi A, Hovig E (2010)
   The Genomic HyperBrowser: inferential genomics at the sequence level
   Genome Biol, 11 (12), R121
   DOI 10.1186/gb-2010-11-12-r121, PubMed 21182759
7. Sørensen O, Andersen A, Olsen H, Alexandr K, Ekstrøm PO, Giercksky KE, Flatmark K (2010)
   Validation and use of microdialysis for determination of pharmacokinetic properties of the chemotherapeutic agent mitomycin C - an experimental study
   BMC Cancer, 10, 469
   DOI 10.1186/1471-2407-10-469, PubMed 20809961

Publications 2009

1. Heuser K, Nagelhus EA, Taubøll E, Indahl U, Berg PR, Lien S, Nakken S, Gjerstad L, Ottersen OP (2009)
   Variants of the genes encoding AQP4 and Kir4.1 are associated with subgroups of patients with temporal lobe epilepsy
   Epilepsy Res, 88 (1), 55-64
   DOI 10.1016/j.eplepsyres.2009.09.023, PubMed 19864112
2. Holla ØL, Nakken S, Mattingsdal M, Ranheim T, Berge KE, Defesche JC, Leren TP (2009)
   Effects of intronic mutations in the LDLR gene on pre-mRNA splicing: Comparison of wet-lab and bioinformatics analyses
   Mol Genet Metab, 96 (4), 245-52
   DOI 10.1016/j.ymgme.2008.12.014, PubMed 19208450
3. Nakken S, Aussedat O, Kristoffersen AB, Holst-Jensen A, Tengs T (2009)
   UniquePrimer - a web utility for design of specific PCR primers and probes
   Ann. Microbiol., 59 (2), 391-393
   DOI 10.1007/BF03178345
4. Nakken S, Rognes T, Hovig E (2009)
   The disruptive positions in human G-quadruplex motifs are less polymorphic and more conserved than their neutral counterparts
   Nucleic Acids Res, 37 (17), 5749-56
   DOI 10.1093/nar/gkp590, PubMed 19617376
5. Nakken S, Rødland EA, Rognes T, Hovig E (2009)
   Large-scale inference of the point mutational spectrum in human segmental duplications
   BMC Genomics, 10, 43
   DOI 10.1186/1471-2164-10-43, PubMed 19161616

Publications 2008

1. Ekstrøm PO (2008)
   Scanning for DNA variants by denaturant capillary electrophoresis
   Methods Mol Biol, 439, 19-34
   DOI 10.1007/978-1-59745-188-8_2, PubMed 18370093
2. Ekstrøm PO, Khrapko K, Li-Sucholeiki XC, Hunter IW, Thilly WG (2008)
   Analysis of mutational spectra by denaturing capillary electrophoresis
   Nat Protoc, 3 (7), 1153-66
   DOI 10.1038/nprot.2008.79, PubMed 18600220
3. Kristensen AT, Wiig JN, Larsen SG, Giercksky KE, Ekstrøm PO (2008)
   Molecular detection (k-ras) of exfoliated tumour cells in the pelvis is a prognostic factor after resection of rectal cancer?
   BMC Cancer, 8, 213
   DOI 10.1186/1471-2407-8-213, PubMed 18655729
4. Nakken KE, Labori KJ, Rødningen OK, Nakken S, Berge KE, Eiklid K, Raeder MG (2008)
   ABCB4 sequence variations in young adults with cholesterol gallstone disease
   Liver Int, 29 (5), 743-7
   DOI 10.1111/j.1478-3231.2008.01914.x, PubMed 19018976
5. Sudo H, Li-Sucholeiki XC, Marcelino LA, Gruhl AN, Herrero-Jimenez P, Zarbl H, Willey JC, Furth EE, Morgenthaler S, Coller HA, Ekstrom PO, Kurzweil R, Gostjeva EV, Thilly WG (2008)
   Fetal-juvenile origins of point mutations in the adult human tracheal-bronchial epithelium: absence of detectable effects of age, gender or smoking status
   Mutat Res, 646 (1-2), 25-40
   DOI 10.1016/j.mrfmmm.2008.08.016, PubMed 18824180

Publications 2007

1. Benson M, Steenhoff Hov DA, Clancy T, Hovig E, Rudemo M, Cardell LO (2007)
   Connectivity can be used to identify key genes in DNA microarray data: a study based on gene expression in nasal polyps before and after treatment with glucocorticoids
   Acta Otolaryngol, 127 (10), 1074-9
   DOI 10.1080/00016480701200277, PubMed 17851899
2. Ekstrøm PO, Bjørheim J, Thilly WG (2007)
   Technology to accelerate pangenomic scanning for unknown point mutations in exonic sequences: cycling temperature capillary electrophoresis (CTCE)
   BMC Genet, 8, 54
   DOI 10.1186/1471-2156-8-54, PubMed 17697348
3. Lind H, Ekstrøm PO, Ryberg D, Skaug V, Andreassen T, Stangeland L, Haugen A, Zienolddiny S (2007)
   Frequency of TP53 mutations in relation to Arg72Pro genotypes in non small cell lung cancer
   Cancer Epidemiol Biomarkers Prev, 16 (10), 2077-81
   DOI 10.1158/1055-9965.EPI-07-0153, PubMed 17932356

Publications 2006

1. Ekstrøm PO, Bjørheim J (2006)
   Evaluation of sieving matrices used to separate alleles by cycling temperature capillary electrophoresis
   Electrophoresis, 27 (10), 1878-85
   DOI 10.1002/elps.200500642, PubMed 16619298
2. Harbo HF, Ekstrøm PO, Lorentzen AR, Sundvold-Gjerstad V, Celius EG, Sawcer S, Spurkland A (2006)
   Coding region polymorphisms in T cell signal transduction genes. Prevalence and association to development of multiple sclerosis
   J Neuroimmunol, 177 (1-2), 40-5
   DOI 10.1016/j.jneuroim.2006.04.021, PubMed 16764945
3. Lind H, Zienolddiny S, Ekstrøm PO, Skaug V, Haugen A (2006)
   Association of a functional polymorphism in the promoter of the MDM2 gene with risk of nonsmall cell lung cancer
   Int J Cancer, 119 (3), 718-21
   DOI 10.1002/ijc.21872, PubMed 16496380
4. Nakken S, Alseth I, Rognes T (2006)
   Computational prediction of the effects of non-synonymous single nucleotide polymorphisms in human DNA repair genes
   Neuroscience, 145 (4), 1273-9
   DOI 10.1016/j.neuroscience.2006.09.004, PubMed 17055652

Publications 2005

1. Bjørheim J, Ekstrøm PO (2005)
   Review of denaturant capillary electrophoresis in DNA variation analysis
   Electrophoresis, 26 (13), 2520-30
   DOI 10.1002/elps.200410403, PubMed 15934053
2. Hinselwood DC, Abrahamsen TW, Ekstrøm PO (2005)
   BRAF mutation detection and identification by cycling temperature capillary electrophoresis
   Electrophoresis, 26 (13), 2553-61
   DOI 10.1002/elps.200410427, PubMed 15948220
3. Hinselwood DC, Warren DJ, Ekstrøm PO (2005)
   High-throughput gender determination using automated denaturant gel capillary electrophoresis
   Electrophoresis, 26 (13), 2562-6
   DOI 10.1002/elps.200410392, PubMed 15934052
4. Li-Sucholeiki XC, Tomita-Mitchell A, Arnold K, Glassner BJ, Thompson T, Murthy JV, Berk L, Lange C, Leong-Morgenthaler PM, MacDougall D, Munro J, Cannon D, Mistry T, Miller A, Deka C, Karger B, Gillespie KM, Ekstrøm PO, Todd JA, Thilly WG (2005)
   Detection and frequency estimation of rare variants in pools of genomic DNA from large populations using mutational spectrometry
   Mutat Res, 570 (2), 267-80
   DOI 10.1016/j.mrfmmm.2004.11.004, PubMed 15708585
5. Lorentzen AR, Celius EG, Ekstrøm PO, Wiencke K, Lie BA, Myhr KM, Ling V, Thorsby E, Vartdal F, Spurkland A, Harbo HF (2005)
   Lack of association with the CD28/CTLA4/ICOS gene region among Norwegian multiple sclerosis patients
   J Neuroimmunol, 166 (1-2), 197-201
   DOI 10.1016/j.jneuroim.2005.06.002, PubMed 16005527

Publications 2004

1. Ekstrøm PO, Bjørge T, Dørum A, Longva AS, Heintz KM, Warren DJ, Hansen S, Gislefoss RE, Hovig E (2004)
   Determination of hereditary mutations in the BRCA1 gene using archived serum samples and capillary electrophoresis
   Anal Chem, 76 (15), 4406-9
   DOI 10.1021/ac049788k, PubMed 15283579

Publications 2003

1. Bjørheim J, Abrahamsen TW, Kristensen AT, Gaudernack G, Ekstrøm PO (2003)
   Approach to analysis of single nucleotide polymorphisms by automated constant denaturant capillary electrophoresis
   Mutat Res, 526 (1-2), 75-83
   DOI 10.1016/s0027-5107(03)00033-2, PubMed 12714185
2. Bjørheim J, Gaudernack G, Giercksky KE, Ekstrøm PO (2003)
   Direct identification of all oncogenic mutants in KRAS exon 1 by cycling temperature capillary electrophoresis
   Electrophoresis, 24 (1-2), 63-9
   DOI 10.1002/elps.200390032, PubMed 12652573
3. Kristensen AT, Bjørheim J, Wiig J, Giercksky KE, Ekstrøm PO (2003)
   DNA variants in the ATM gene are not associated with sporadic rectal cancer in a Norwegian population-based study
   Int J Colorectal Dis, 19 (1), 49-54
   DOI 10.1007/s00384-003-0519-7, PubMed 12827413
4. Minarik M, Minarikova L, Bjørheim J, Ekstrøm PO (2003)
   Cycling gradient capillary electrophoresis: a low-cost tool for high-throughput analysis of genetic variations
   Electrophoresis, 24 (11), 1716-22
   DOI 10.1002/elps.200305384, PubMed 12783447

Publications 2002

1. Bjørheim J, Minarik M, Gaudernack G, Ekstrøm PO (2002)
   Mutation detection in KRAS Exon 1 by constant denaturant capillary electrophoresis in 96 parallel capillaries
   Anal Biochem, 304 (2), 200-5
   DOI 10.1006/abio.2002.5629, PubMed 12009696
2. Ekstrøm PO, Bjørheim J (2002)
   Reducing the cost of consumables used for ABI 310 genetic analyzer
   Anal Biochem, 306 (1), 148-9
   DOI 10.1006/abio.2002.5656, PubMed 12069426
3. Ekstrøm PO, Bjørheim J, Gaudernack G, Giercksky KE (2002)
   Population screening of single-nucleotide polymorphisms exemplified by analysis of 8000 alleles
   J Biomol Screen, 7 (6), 501-6
   DOI 10.1177/1087057102238623, PubMed 14599347
4. Kristensen AT, Bjørheim J, Ekstrøm PO (2002)
   Detection of mutations in exon 8 of TP53 by temperature gradient 96-capillary array electrophoresis
   Biotechniques, 33 (3), 650-3
   DOI 10.2144/02333pf01, PubMed 12238774

Publications 2001

1. Bjørheim J, Ekstrøm PO, Fossberg E, Børresen-Dale AL, Gaudernack G (2001)
   Automated constant denaturant capillary electrophoresis applied for detection of KRAS exon 1 mutations
   Biotechniques, 30 (5), 972-5
   DOI 10.2144/01305st01, PubMed 11355359
2. Bjørheim J, Gaudernack G, Ekstrøm PO (2001)
   Mutation analysis of TP53 exons 5-8 by automated constant denaturant capillary electrophoresis
   Tumour Biol, 22 (5), 323-7
   DOI 10.1159/000050634, PubMed 11553863

Publications 2000

1. Ekstrøm PO, Wasserkort R, Minarik M, Foret F, Thilly WG (2000)
   Two-point fluorescence detection and automated fraction collection applied to constant denaturant capillary electrophoresis
   Biotechniques, 29 (3), 582-4, 586-9
   DOI 10.2144/00293rr01, PubMed 10997272

Publications 1999

1. Ekstrøm PO, Børresen-Dale AL, Qvist H, Giercksky KE, Thilly WG (1999)
   Detection of low-frequency mutations in exon 8 of the TP53 gene by constant denaturant capillary electrophoresis (CDCE)
   Biotechniques, 27 (1), 128-34
   DOI 10.2144/99271rr01, PubMed 10407675

Publications 1997

1. Ekstrøm PO, Andersen A, Saeter G, Giercksky KE, Slørdal L (1997)
   Continuous intratumoral microdialysis during high-dose methotrexate therapy in a patient with malignant fibrous histiocytoma of the femur: a case report
   Cancer Chemother Pharmacol, 39 (3), 267-72
   DOI 10.1007/s002800050571, PubMed 8996531
2. Ekstrøm PO, Giercksky KE, Andersen A, Bruland OS, Slørdal L (1997)
   Intratumoral differences in methotrexate levels within human osteosarcoma xenografts studied by microdialysis
   Life Sci, 61 (19), PL275-80
   DOI 10.1016/s0024-3205(97)00839-4, PubMed 9364204
3. Ekstrøm PO, Giercksky KE, Andersen A, Slørdal L (1997)
   Alterations in methotrexate pharmacokinetics by naproxen in the rat as measured by microdialysis
   Life Sci, 60 (24), PL 359-64
   DOI 10.1016/s0024-3205(97)00241-5, PubMed 9188769

Publications 1996

1. Ekstrøm PO, Andersen A, Warren DJ, Giercksky KE, Slørdal L (1996)
   Determination of extracellular methotrexate tissue levels by microdialysis in a rat model
   Cancer Chemother Pharmacol, 37 (5), 394-400
   DOI 10.1007/s002800050403, PubMed 8599860

Publications 1995

1. Ekstrøm PO, Anderson A, Warren DJ, Giercksky KE, Slørdal L (1995)
   Pharmacokinetics of different doses of methotrexate at steady state by in situ microdialysis in a rat model
   Cancer Chemother Pharmacol, 36 (4), 283-9
   DOI 10.1007/BF00689044, PubMed 7628046