Saykat Das

  • Postdoc; BSc, MSc, PhD
  • +47 22 78 23 19

HSØ (SECAR)

Education

2025/-:

Postdoc, in Cellular Therapy (SECAR), Oslo Cancer Cluster

2020/2023

PhD in Immunology, Faculty of medicine, University of Oslo, Norway

2017/2019

MSc in Molecular Biology, Department of Bioscience, University of Oslo, Norway

2012/2016

BSc in Biochemistry and Biotechnology, USTC, Bangladesh

 

Work experience

2025/-:

Postdoc researcher, in Cellular Therapy, OUS Radiumhospitalet, Oslo, Norway

2024/2025

Researcher, Department of Infectious diseases, OUS Ullevål Sykehus, Oslo, Norway

2023/2024

Researcher, Faculty of medicine, University of Oslo, Norway

2020/2023

PhD researcher, Faculty of medicine, University of Oslo, Norway

2018/2020

Research Assistant, Faculty of medicine, University of Oslo, Norway

 

Research Interest

Identification, development and functional testing of cancer restricted safety-enhanced CAR-T cells (SECARs)

Publications

1.      Iversen R, Heggelund JE, Das S, Høydahl LS, Sollid LM. Enzyme-activating B-cell receptors boost antigen presentation to pathogenic T cells in gluten-sensitive autoimmunity. Nat Commun. 2025 Mar 10;16(1):2387. doi: 10.1038/s41467-025-57564-5. PMID: 40064932; PMCID: PMC11894174

2.      Das S, Stamnaes J, Høydahl LS, Skagen C, Lundin KEA, Jahnsen J, Sollid LM, Iversen R. Selective activation of naïve B cells with unique epitope specificity shapes autoantibody formation in celiac disease. J Autoimmun. 2024 May 15;146:103241. doi: 10.1016/j.jaut.2024.103241. Epub ahead of print. PMID: 38754235

3.      Heggelund JE, Das S, Stamnaes J, Iversen R, Sollid LM. Autoantibody binding and unique enzyme-substrate intermediate conformation of human transglutaminase 3. Nat Commun. 2023 Oct 5;14(1):6216. doi: 10.1038/s41467-023-42004-z. PMID: 37798283; PMCID: PMC10556103

4.       Das S, Stamnaes J, Kemppainen E, Hervonen K, Lundin KEA, Parmar N, Jahnsen FL, Jahnsen J, Lindfors K, Salmi T, Iversen R, Sollid LM. Separate Gut Plasma Cell Populations Produce Auto-Antibodies against Transglutaminase 2 and Transglutaminase 3 in Dermatitis Herpetiformis. Adv Sci (Weinh). 2023 Sep;10(25):e2300401. doi: 10.1002/advs.202300401. PMID: 37424036; PMCID: PMC10477854