Publications 2024

Agger AE, Samara A, Geng T, Olstad OK, Reseland JE (2024)
Mimicking and in vitro validating chronic inflammation in human gingival fibroblasts
Arch Oral Biol, 169, 106113
DOI 10.1016/j.archoralbio.2024.106113, PubMed 39447377

Publications 2023

Cross T, Haug KBF, Brusletto BS, Ommundsen SK, Trøseid AS, Aspelin T, Olstad OK, Aass HCD, Galtung HK, Utheim TP, Jensen JL, Øvstebø R (2023)
Non-Coding RNA in Salivary Extracellular Vesicles: A New Frontier in Sjögren's Syndrome Diagnostics?
Int J Mol Sci, 24 (17)
DOI 10.3390/ijms241713409, PubMed 37686214

Cross T, Øvstebø R, Brusletto BS, Trøseid AS, Olstad OK, Aspelin T, Jackson CJ, Chen X, Utheim TP, Haug KBF (2023)
RNA Profiles of Tear Fluid Extracellular Vesicles in Patients with Dry Eye-Related Symptoms
Int J Mol Sci, 24 (20)
DOI 10.3390/ijms242015390, PubMed 37895069

Lekva T, Michelsen AE, Roland MCP, Norwitz ER, Estensen ME, Olstad OK, Akkouh IA, Henriksen T, Bollerslev J, Aukrust P, Ueland T (2023)
Increased ferroptosis in leukocytes from preeclamptic women involving the long non-coding taurine upregulated gene 1 (TUG1)
J Intern Med, 295 (2), 181-195
DOI 10.1111/joim.13732, PubMed 37870937

Yang Y, Geng T, Samara A, Olstad OK, He J, Agger AE, Skallerud BH, Landin MA, Heyward CA, Pullisaar H, Reseland JE (2023)
Recombinant irisin enhances the extracellular matrix formation, remodeling potential, and differentiation of human periodontal ligament cells cultured in 3D
J Periodontal Res, 58 (2), 336-349
DOI 10.1111/jre.13094, PubMed 36625247

Aas V, Øvstebø R, Brusletto BS, Aspelin T, Trøseid AS, Qureshi S, Eid DSO, Olstad OK, Nyman TA, Haug KBF (2023)
Distinct microRNA and protein profiles of extracellular vesicles secreted from myotubes from morbidly obese donors with type 2 diabetes in response to electrical pulse stimulation
Front Physiol, 14, 1143966
DOI 10.3389/fphys.2023.1143966, PubMed 37064893

Publications 2022

Brusletto BS, Hellerud BC, Olstad OK, Øvstebø R, Brandtzaeg P (2022)
Transcriptomic changes in the large organs in lethal meningococcal shock are reflected in a porcine shock model
Front Cell Infect Microbiol, 12, 908204
DOI 10.3389/fcimb.2022.908204, PubMed 36034711

Datta HK, Kringen MK, Tuck SP, Salpingidou G, Olstad OK, Gautvik KM, Cockell SJ, Gautvik VT, Prediger M, Wu JJ, Birch MA, Reppe S (2022)
Mechanical-Stress-Related Epigenetic Regulation of ZIC1 Transcription Factor in the Etiology of Postmenopausal Osteoporosis
Int J Mol Sci, 23 (6)
DOI 10.3390/ijms23062957, PubMed 35328378

Gautvik KM, Olstad OK, Raue U, Gautvik VT, Kvernevik KJ, Utheim TP, Ravnum S, Kirkegaard C, Wiig H, Jones G, Pilling LC, Trappe S, Raastad T, Reppe S (2022)
Heavy-load exercise in older adults activates vasculogenesis and has a stronger impact on muscle gene expression than in young adults
Eur Rev Aging Phys Act, 19 (1), 23
DOI 10.1186/s11556-022-00304-1, PubMed 36182918

Gautvik KM, Sachse D, Hinton AC, Olstad OK, Kiel DP, Hsu YH, Utheim TP, Lary CW, Reppe S (2022)
In silico discovery of blood cell macromolecular associations
BMC Genom Data, 23 (1), 57
DOI 10.1186/s12863-022-01077-3, PubMed 35879676

Publications 2021

Bjørnetrø T, Steffensen LA, Vestad B, Brusletto BS, Olstad OK, Trøseid AM, Aass HCD, Haug KBF, Llorente A, Bøe SO, Lång A, Samiappan R, Redalen KR, Øvstebø R, Ree AH (2021)
Uptake of circulating extracellular vesicles from rectal cancer patients and differential responses by human monocyte cultures
FEBS Open Bio, 11 (3), 724-740
DOI 10.1002/2211-5463.13098, PubMed 33512765

Eidet JR, Akopian M, Olstad OK, Jørstad ØK, Moe MC, Petrovski G, Pepaj M (2021)
The acute phase response protein SERPINA3 is increased in tear fluid from the unaffected eyes of patients with unilateral acute anterior uveitis
J Ophthalmic Inflamm Infect, 11 (1), 19
DOI 10.1186/s12348-021-00249-z, PubMed 34212267

Lekva T, Roland MCP, Estensen ME, Norwitz ER, Tilburgs T, Henriksen T, Bollerslev J, Normann KR, Magnus P, Olstad OK, Aukrust P, Ueland T (2021)
Dysregulated non-coding telomerase RNA component and associated exonuclease XRN1 in leucocytes from women developing preeclampsia-possible link to enhanced senescence
Sci Rep, 11 (1), 19735
DOI 10.1038/s41598-021-99140-z, PubMed 34611223

Lekva T, Roland MCP, Estensen ME, Norwitz ER, Tilburgs T, Henriksen T, Bollerslev J, Normann KR, Magnus P, Olstad OK, Aukrust P, Ueland T (2021)
Author Correction: Dysregulated non-coding telomerase RNA component and associated exonuclease XRN1 in leucocytes from women developing preeclampsia-possible link to enhanced senescence
Sci Rep, 11 (1), 22572
DOI 10.1038/s41598-021-00917-z, PubMed 34782619

Publications 2020

Bornstedt ME, Gjerlaugsen N, Olstad OK, Berg JP, Bredahl MK, Thorsby PM (2020)
Vitamin D metabolites influence expression of genes concerning cellular viability and function in insulin producing β-cells (INS1E)
Gene, 746, 144649
DOI 10.1016/j.gene.2020.144649, PubMed 32251702

Brusletto BS, Løberg EM, Hellerud BC, Goverud IL, Berg JP, Olstad OK, Gopinathan U, Brandtzaeg P, Øvstebø R (2020)
Extensive Changes in Transcriptomic "Fingerprints" and Immunological Cells in the Large Organs of Patients Dying of Acute Septic Shock and Multiple Organ Failure Caused by Neisseria meningitidis
Front Cell Infect Microbiol, 10, 42
DOI 10.3389/fcimb.2020.00042, PubMed 32154187

Eidet JR, Jørstad ØK, Fostad IG, Olstad OK, Sørland RØ, Moe MC, Petrovski G, Pepaj M (2020)
Unilateral acute anterior uveitis is associated with ipsilateral changes in the tear fluid proteome that involves the LXR/RXR pathway
J Ophthalmic Inflamm Infect, 10 (1), 13
DOI 10.1186/s12348-020-00204-4, PubMed 32458144

García-Posadas L, Hodges RR, Utheim TP, Olstad OK, Delcroix V, Makarenkova HP, Dartt DA (2020)
Lacrimal Gland Myoepithelial Cells Are Altered in a Mouse Model of Dry Eye Disease
Am J Pathol, 190 (10), 2067-2079
DOI 10.1016/j.ajpath.2020.06.013, PubMed 32679229

Gautvik KM, Günther CC, Prijatelj V, Medina-Gomez C, Shevroja E, Rad LH, Yazdani M, Lindalen E, Valland H, Gautvik VT, Olstad OK, Holden M, Rivadeneira F, Utheim TP, Reppe S (2020)
Distinct Subsets of Noncoding RNAs Are Strongly Associated With BMD and Fracture, Studied in Weight-Bearing and Non-Weight-Bearing Human Bone
J Bone Miner Res, 35 (6), 1065-1076
DOI 10.1002/jbmr.3974, PubMed 32017184

Grønlien HK, Christoffersen TE, Nystrand CF, Garabet L, Syvertsen T, Moe MK, Olstad OK, Jonassen CM (2020)
Cytokine and Gene Expression Profiling in Patients with HFE-Associated Hereditary Hemochromatosis according to Genetic Profile
Acta Haematol, 144 (4), 446-457
DOI 10.1159/000511551, PubMed 33326952

Khan AZ, Jackson CJ, Utheim TP, Reppe S, Sapkota D, Olstad OK, Thiede B, Eidet JR (2020)
Sericin-Induced Melanogenesis in Cultured Retinal Pigment Epithelial Cells Is Associated with Elevated Levels of Hydrogen Peroxide and Inflammatory Proteins
Molecules, 25 (19)
DOI 10.3390/molecules25194395, PubMed 32987810

Ness C, Katta K, Garred Ø, Kumar T, Olstad OK, Petrovski G, Moe MC, Noer A (2020)
Integrated differential DNA methylation and gene expression of formalin-fixed paraffin-embedded uveal melanoma specimens identifies genes associated with early metastasis and poor prognosis
Exp Eye Res, 203, 108426
DOI 10.1016/j.exer.2020.108426, PubMed 33387485

Olstad OK, Gautvik VT, LeBlanc M, Kvernevik KJ, Utheim TP, Runningen A, Wiig H, Kirkegaard C, Raastad T, Reppe S, Gautvik KM (2020)
Postmenopausal osteoporosis is a musculoskeletal disease with a common genetic trait which responds to strength training: a translational intervention study
Ther Adv Musculoskelet Dis, 12, 1759720X20929443
DOI 10.1177/1759720X20929443, PubMed 32536985

Publications 2019

Myhrstad MCW, de Mello VD, Dahlman I, Kolehmainen M, Paananen J, Rundblad A, Carlberg C, Olstad OK, Pihlajamäki J, Holven KB, Hermansen K, Dragsted LO, Gunnarsdottir I, Cloetens L, Storm MU, Åkesson B, Rosqvist F, Hukkanen J, Herzig KH, Risérus U, Thorsdottir I, Poutanen KS, Savolainen MJ, Schwab U, Arner P et al. (2019)
Healthy Nordic Diet Modulates the Expression of Genes Related to Mitochondrial Function and Immune Response in Peripheral Blood Mononuclear Cells from Subjects with Metabolic Syndrome-A SYSDIET Sub-Study
Mol Nutr Food Res, 63 (13), e1801405
DOI 10.1002/mnfr.201801405, PubMed 30964598

Publications 2018

Oma I, Olstad OK, Andersen JK, Lyberg T, Molberg Ø, Fostad I, Wang Fagerland M, Almdahl SM, Rynning SE, Yndestad A, Aukrust P, Whist JE, Hollan I (2018)
Differential expression of vitamin D associated genes in the aorta of coronary artery disease patients with and without rheumatoid arthritis
PLoS One, 13 (8), e0202346
DOI 10.1371/journal.pone.0202346, PubMed 30138371

Aabel P, Utheim TP, Olstad OK, Rask-Andersen H, Dilley RJ, von Unge M (2018)
Transcription and microRNA Profiling of Cultured Human Tympanic Membrane Epidermal Keratinocytes
J Assoc Res Otolaryngol, 19 (3), 243-260
DOI 10.1007/s10162-018-0660-1, PubMed 29623476

Publications 2017

Alonso N, Estrada K, Albagha OME, Herrera L, Reppe S, Olstad OK, Gautvik KM, Ryan NM, Evans KL, Nielson CM, Hsu YH, Kiel DP, Markozannes G, Ntzani EE, Evangelou E, Feenstra B, Liu X, Melbye M, Masi L, Brandi ML, Riches P, Daroszewska A, Olmos JM, Valero C, Castillo J et al. (2017)
Identification of a novel locus on chromosome 2q13, which predisposes to clinical vertebral fractures independently of bone density
Ann Rheum Dis, 77 (3), 378-385
DOI 10.1136/annrheumdis-2017-212469, PubMed 29170203

Gopinathan U, Øvstebø R, Brusletto BS, Olstad OK, Kierulf P, Brandtzaeg P, Berg JP (2017)
Transcriptomic data from two primary cell models stimulating human monocytes suggest inhibition of oxidative phosphorylation and mitochondrial function by N. meningitidis which is partially up-regulated by IL-10
BMC Immunol, 18 (1), 46
DOI 10.1186/s12865-017-0229-5, PubMed 29078758

Johnsen EO, Frøen RC, Olstad OK, Nicolaissen B, Petrovski G, Moe MC, Noer A (2017)
Proliferative Cells Isolated from the Adult Human Peripheral Retina only Transiently Upregulate Key Retinal Markers upon Induced Differentiation
Curr Eye Res, 43 (3), 340-349
DOI 10.1080/02713683.2017.1403630, PubMed 29161152

Ness C, Garred Ø, Eide NA, Kumar T, Olstad OK, Bærland TP, Petrovski G, Moe MC, Noer A (2017)
Multicellular tumor spheroids of human uveal melanoma induce genes associated with anoikis resistance, lipogenesis, and SSXs
Mol Vis, 23, 680-694
PubMed 29033534

Reppe S, Lien TG, Hsu YH, Gautvik VT, Olstad OK, Yu R, Bakke HG, Lyle R, Kringen MK, Glad IK, Gautvik KM (2017)
Distinct DNA methylation profiles in bone and blood of osteoporotic and healthy postmenopausal women
Epigenetics, 12 (8), 674-687
DOI 10.1080/15592294.2017.1345832, PubMed 28650214

Publications 2016

Eidet JR, Reppe S, Pasovic L, Olstad OK, Lyberg T, Khan AZ, Fostad IG, Chen DF, Utheim TP (2016)
The Silk-protein Sericin Induces Rapid Melanization of Cultured Primary Human Retinal Pigment Epithelial Cells by Activating the NF-κB Pathway
Sci Rep, 6, 22671
DOI 10.1038/srep22671, PubMed 26940175

Pasovic L, Eidet JR, Olstad OK, Chen DF, Lyberg T, Utheim TP (2016)
Impact of Storage Temperature on the Expression of Cell Survival Genes in Cultured ARPE-19 Cells
Curr Eye Res, 42 (1), 134-144
DOI 10.3109/02713683.2016.1145236, PubMed 27259952

Pathak M, Olstad OK, Drolsum L, Moe MC, Smorodinova N, Kalasova S, Jirsova K, Nicolaissen B, Noer A (2016)
The effect of culture medium and carrier on explant culture of human limbal epithelium: A comparison of ultrastructure, keratin profile and gene expression
Exp Eye Res, 153, 122-132
DOI 10.1016/j.exer.2016.09.012, PubMed 27702552

Rother MB, Jensen K, van der Burg M, van de Bovenkamp FS, Kroek R, van IJcken WF, van der Velden VH, Cupedo T, Olstad OK, van Dongen JJ, van Zelm MC (2016)
Decreased IL7Rα and TdT expression underlie the skewed immunoglobulin repertoire of human B-cell precursors from fetal origin
Sci Rep, 6, 33924
DOI 10.1038/srep33924, PubMed 27658954

Skarpengland T, Holm S, Scheffler K, Gregersen I, Dahl TB, Suganthan R, Segers FM, Østlie I, Otten JJ, Luna L, Ketelhuth DF, Lundberg AM, Neurauter CG, Hildrestrand G, Skjelland M, Bjørndal B, Svardal AM, Iversen PO, Hedin U, Nygård S, Olstad OK, Krohg-Sørensen K, Slupphaug G, Eide L, Kuśnierczyk A et al. (2016)
Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice
Sci Rep, 6, 28337
DOI 10.1038/srep28337, PubMed 27328939

Utheim TP, Islam R, Fostad IG, Eidet JR, Sehic A, Olstad OK, Dartt DA, Messelt EB, Griffith M, Pasovic L (2016)
Storage Temperature Alters the Expression of Differentiation-Related Genes in Cultured Oral Keratinocytes
PLoS One, 11 (3), e0152526
DOI 10.1371/journal.pone.0152526, PubMed 27023475

Utheim TP, Salvanos P, Utheim ØA, Ræder S, Pasovic L, Olstad OK, de la Paz MF, Sehic A (2016)
Transcriptome Analysis of Cultured Limbal Epithelial Cells on an Intact Amniotic Membrane following Hypothermic Storage in Optisol-GS
J Funct Biomater, 7 (1)
DOI 10.3390/jfb7010004, PubMed 26901233

Veréb Z, Póliska S, Albert R, Olstad OK, Boratkó A, Csortos C, Moe MC, Facskó A, Petrovski G (2016)
Role of Human Corneal Stroma-Derived Mesenchymal-Like Stem Cells in Corneal Immunity and Wound Healing
Sci Rep, 6, 26227
DOI 10.1038/srep26227, PubMed 27195722

Publications 2015

Hellerud BC, Olstad OK, Nielsen EW, Trøseid AM, Skadberg Ø, Thorgersen EB, Vege Å, Mollnes TE, Brandtzæg P (2015)
Massive Organ Inflammation in Experimental and in Clinical Meningococcal Septic Shock
Shock, 44 (5), 458-69
DOI 10.1097/SHK.0000000000000441, PubMed 26473439

Lau C, Nygård S, Fure H, Olstad OK, Holden M, Lappegård KT, Brekke OL, Espevik T, Hovig E, Mollnes TE (2015)
CD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray
PLoS One, 10 (2), e0117261
DOI 10.1371/journal.pone.0117261, PubMed 25706641

Lau C, Olstad OK, Holden M, Nygård S, Fure H, Lappegård KT, Brekke OL, Espevik T, Hovig E, Mollnes TE (2015)
Gene expression profiling of Gram-negative bacteria-induced inflammation in human whole blood: The role of complement and CD14-mediated innate immune response
Genom Data, 5, 176-83
DOI 10.1016/j.gdata.2015.05.019, PubMed 26484252

Meen AJ, Drevon CA, Pejler G, Jenssen TG, Olstad OK, Åbrink M, Kolset SO (2015)
Serglycin protects against high fat diet-induced increase in serum LDL in mice
Glycoconj J, 32 (9), 703-14
DOI 10.1007/s10719-015-9621-7, PubMed 26391682

Reppe S, Noer A, Grimholt RM, Halldórsson BV, Medina-Gomez C, Gautvik VT, Olstad OK, Berg JP, Datta H, Estrada K, Hofman A, Uitterlinden AG, Rivadeneira F, Lyle R, Collas P, Gautvik KM (2015)
Methylation of bone SOST, its mRNA, and serum sclerostin levels correlate strongly with fracture risk in postmenopausal women
J Bone Miner Res, 30 (2), 249-56
DOI 10.1002/jbmr.2342, PubMed 25155887

Tangen JM, Tierens A, Caers J, Binsfeld M, Olstad OK, Trøseid AM, Wang J, Tjønnfjord GE, Hetland G (2015)
Immunomodulatory effects of the Agaricus blazei Murrill-based mushroom extract AndoSan in patients with multiple myeloma undergoing high dose chemotherapy and autologous stem cell transplantation: a randomized, double blinded clinical study
Biomed Res Int, 2015, 718539
DOI 10.1155/2015/718539, PubMed 25664323

Publications 2014

Capulli M, Olstad OK, Onnerfjord P, Tillgren V, Muraca M, Gautvik KM, Heinegård D, Rucci N, Teti A (2014)
The C-terminal domain of chondroadherin: a new regulator of osteoclast motility counteracting bone loss
J Bone Miner Res, 29 (8), 1833-46
DOI 10.1002/jbmr.2206, PubMed 24616121

Gopinathan U, Brusletto BS, Olstad OK, Kierulf P, Berg JP, Brandtzaeg P, Øvstebø R (2014)
IL-10 immunodepletion from meningococcal sepsis plasma induces extensive changes in gene expression and cytokine release in stimulated human monocytes
Innate Immun, 21 (4), 429-49
DOI 10.1177/1753425914547743, PubMed 25233959

Rucci N, Capulli M, Olstad OK, Önnerfjord P, Tillgren V, Gautvik KM, Heinegård D, Teti A (2014)
The α2β1 binding domain of chondroadherin inhibits breast cancer-induced bone metastases and impairs primary tumour growth: a preclinical study
Cancer Lett, 358 (1), 67-75
DOI 10.1016/j.canlet.2014.12.032, PubMed 25529009

Stormo C, Kringen MK, Lyle R, Olstad OK, Sachse D, Berg JP, Piehler AP (2014)
RNA-sequencing analysis of HepG2 cells treated with atorvastatin
PLoS One, 9 (8), e105836
DOI 10.1371/journal.pone.0105836, PubMed 25153832

Vilming Elgaaen B, Olstad OK, Haug KB, Brusletto B, Sandvik L, Staff AC, Gautvik KM, Davidson B (2014)
Global miRNA expression analysis of serous and clear cell ovarian carcinomas identifies differentially expressed miRNAs including miR-200c-3p as a prognostic marker
BMC Cancer, 14, 80
DOI 10.1186/1471-2407-14-80, PubMed 24512620

Publications 2013

Engelsvold DH, Utheim TP, Olstad OK, Gonzalez P, Eidet JR, Lyberg T, Trøseid AM, Dartt DA, Raeder S (2013)
miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium
Exp Eye Res, 115, 189-98
DOI 10.1016/j.exer.2013.07.003, PubMed 23872359

Jensen K, Brusletto BS, Aass HC, Olstad OK, Kierulf P, Gautvik KM (2013)
Transcriptional profiling of mRNAs and microRNAs in human bone marrow precursor B cells identifies subset- and age-specific variations
PLoS One, 8 (7), e70721
DOI 10.1371/journal.pone.0070721, PubMed 23936243

Jensen K, Rother MB, Brusletto BS, Olstad OK, Dalsbotten Aass HC, van Zelm MC, Kierulf P, Gautvik KM (2013)
Increased ID2 levels in adult precursor B cells as compared with children is associated with impaired Ig locus contraction and decreased bone marrow output
J Immunol, 191 (3), 1210-9
DOI 10.4049/jimmunol.1203462, PubMed 23825313

Lekva T, Berg JP, Heck A, Lyngvi Fougner S, Olstad OK, Ringstad G, Bollerslev J, Ueland T (2013)
Attenuated RORC expression in the presence of EMT progression in somatotroph adenomas following treatment with somatostatin analogs is associated with poor clinical recovery
PLoS One, 8 (6), e66927
DOI 10.1371/journal.pone.0066927, PubMed 23825587

Lekva T, Berg JP, Lyle R, Heck A, Ringstad G, Olstad OK, Michelsen AE, Casar-Borota O, Bollerslev J, Ueland T (2013)
Epithelial splicing regulator protein 1 and alternative splicing in somatotroph adenomas
Endocrinology, 154 (9), 3331-43
DOI 10.1210/en.2013-1051, PubMed 23825128

Veréb Z, Albert R, Póliska S, Olstad OK, Akhtar S, Moe MC, Petrovski G (2013)
Comparison of upstream regulators in human ex vivo cultured cornea limbal epithelial stem cells and differentiated corneal epithelial cells
BMC Genomics, 14, 900
DOI 10.1186/1471-2164-14-900, PubMed 24344983

Publications 2012

Albert R, Veréb Z, Csomós K, Moe MC, Johnsen EO, Olstad OK, Nicolaissen B, Rajnavölgyi E, Fésüs L, Berta A, Petrovski G (2012)
Cultivation and characterization of cornea limbal epithelial stem cells on lens capsule in animal material-free medium
PLoS One, 7 (10), e47187
DOI 10.1371/journal.pone.0047187, PubMed 23056608

Bøhn SK, Russnes KM, Sakhi AK, Thoresen M, Holden M, Moskaug JØ, Myhrstad MC, Olstad OK, Smeland S, Blomhoff R (2012)
Stress associated gene expression in blood cells is related to outcome in radiotherapy treated head and neck cancer patients
BMC Cancer, 12, 426
DOI 10.1186/1471-2407-12-426, PubMed 23009663

Dahm AE, Eilertsen AL, Goeman J, Olstad OK, Ovstebø R, Kierulf P, Mowinckel MC, Skretting G, Sandset PM (2012)
A microarray study on the effect of four hormone therapy regimens on gene transcription in whole blood from healthy postmenopausal women
Thromb Res, 130 (1), 45-51
DOI 10.1016/j.thromres.2011.12.009, PubMed 22217510

Elgaaen BV, Olstad OK, Sandvik L, Odegaard E, Sauer T, Staff AC, Gautvik KM (2012)
ZNF385B and VEGFA are strongly differentially expressed in serous ovarian carcinomas and correlate with survival
PLoS One, 7 (9), e46317
DOI 10.1371/journal.pone.0046317, PubMed 23029477

Gopinathan U, Ovstebø R, Olstad OK, Brusletto B, Dalsbotten Aass HC, Kierulf P, Brandtzaeg P, Berg JP (2012)
Global effect of interleukin-10 on the transcriptional profile induced by Neisseria meningitidis in human monocytes
Infect Immun, 80 (11), 4046-54
DOI 10.1128/IAI.00386-12, PubMed 22966040

Johnson E, Førland DT, Hetland G, Sætre L, Olstad OK, Lyberg T (2012)
Effect of AndoSan™ on expression of adhesion molecules and production of reactive oxygen species in human monocytes and granulocytes in vivo
Scand J Gastroenterol, 47 (8-9), 984-92
DOI 10.3109/00365521.2012.660544, PubMed 22564240

Lekva T, Berg JP, Fougner SL, Olstad OK, Ueland T, Bollerslev J (2012)
Gene expression profiling identifies ESRP1 as a potential regulator of epithelial mesenchymal transition in somatotroph adenomas from a large cohort of patients with acromegaly
J Clin Endocrinol Metab, 97 (8), E1506-14
DOI 10.1210/jc.2012-1760, PubMed 22585092

Medina-Gomez C, Kemp JP, Estrada K, Eriksson J, Liu J, Reppe S, Evans DM, Heppe DH, Vandenput L, Herrera L, Ring SM, Kruithof CJ, Timpson NJ, Zillikens MC, Olstad OK, Zheng HF, Richards JB, St Pourcain B, Hofman A, Jaddoe VW, Smith GD, Lorentzon M, Gautvik KM, Uitterlinden AG, Brommage R et al. (2012)
Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus
PLoS Genet, 8 (7), e1002718
DOI 10.1371/journal.pgen.1002718, PubMed 22792070

Narverud I, Halvorsen B, Nenseter MS, Retterstøl K, Yndestad A, Dahl TB, Ulven SM, Olstad OK, Ose L, Holven KB, Aukrust P (2012)
Oxidized LDL level is related to gene expression of tumour necrosis factor super family members in children and young adults with familial hypercholesterolaemia
J Intern Med, 273 (1), 69-78
DOI 10.1111/j.1365-2796.2012.02584.x, PubMed 22891927

Reppe S, Sachse D, Olstad OK, Gautvik VT, Sanderson P, Datta HK, Berg JP, Gautvik KM (2012)
Identification of transcriptional macromolecular associations in human bone using browser based in silico analysis in a giant correlation matrix
Bone, 53 (1), 69-78
DOI 10.1016/j.bone.2012.11.015, PubMed 23195995

Shahdadfar A, Haug K, Pathak M, Drolsum L, Olstad OK, Johnsen EO, Petrovski G, Moe MC, Nicolaissen B (2012)
Ex vivo expanded autologous limbal epithelial cells on amniotic membrane using a culture medium with human serum as single supplement
Exp Eye Res, 97 (1), 1-9
DOI 10.1016/j.exer.2012.01.013, PubMed 22342952

Stavik B, Skretting G, Olstad OK, Sletten M, Dehli Vigeland M, Sandset PM, Iversen N (2012)
TFPI alpha and beta regulate mRNAs and microRNAs involved in cancer biology and in the immune system in breast cancer cells
PLoS One, 7 (10), e47184
DOI 10.1371/journal.pone.0047184, PubMed 23071754

Publications 2011

Berdal JE, Mollnes TE, Wæhre T, Olstad OK, Halvorsen B, Ueland T, Laake JH, Furuseth MT, Maagaard A, Kjekshus H, Aukrust P, Jonassen CM (2011)
Excessive innate immune response and mutant D222G/N in severe A (H1N1) pandemic influenza
J Infect, 63 (4), 308-16
DOI 10.1016/j.jinf.2011.07.004, PubMed 21781987

Jemtland R, Holden M, Reppe S, Olstad OK, Reinholt FP, Gautvik VT, Refvem H, Frigessi A, Houston B, Gautvik KM (2011)
Molecular disease map of bone characterizing the postmenopausal osteoporosis phenotype
J Bone Miner Res, 26 (8), 1793-801
DOI 10.1002/jbmr.396, PubMed 21452281

Publications 2010

Elgaaen BV, Haug KB, Wang J, Olstad OK, Fortunati D, Onsrud M, Staff AC, Sauer T, Gautvik KM (2010)
POLD2 and KSP37 (FGFBP2) correlate strongly with histology, stage and outcome in ovarian carcinomas
PLoS One, 5 (11), e13837
DOI 10.1371/journal.pone.0013837, PubMed 21079801

Jensen K, Schaffer L, Olstad OK, Bechensteen AG, Hellebostad M, Tjønnfjord GE, Kierulf P, Gautvik KM, Osnes LT (2010)
Striking decrease in the total precursor B-cell compartment during early childhood as evidenced by flow cytometry and gene expression changes
Pediatr Hematol Oncol, 27 (1), 31-45
DOI 10.3109/08880010903420687, PubMed 20121553

Kalogeropoulos M, Varanasi SS, Olstad OK, Sanderson P, Gautvik VT, Reppe S, Francis RM, Gautvik KM, Birch MA, Datta HK (2010)
Zic1 transcription factor in bone: neural developmental protein regulates mechanotransduction in osteocytes
FASEB J, 24 (8), 2893-903
DOI 10.1096/fj.09-148908, PubMed 20354137

Melhus G, Brorson SH, Baekkevold ES, Andersson G, Jemtland R, Olstad OK, Reinholt FP (2010)
Gene expression and distribution of key bone turnover markers in the callus of estrogen-deficient, vitamin D-depleted rats
Calcif Tissue Int, 87 (1), 77-89
DOI 10.1007/s00223-010-9371-2, PubMed 20495792

Varanasi SS, Olstad OK, Swan DC, Sanderson P, Gautvik VT, Reppe S, Francis RM, Gautvik KM, Datta HK (2010)
Skeletal site-related variation in human trabecular bone transcriptome and signaling
PLoS One, 5 (5), e10692
DOI 10.1371/journal.pone.0010692, PubMed 20502692

Publications 2009

Lekva T, Bollerslev J, Kristo C, Olstad OK, Ueland T, Jemtland R (2009)
The glucocorticoid-induced leucine zipper gene (GILZ) expression decreases after successful treatment of patients with endogenous Cushing's syndrome and may play a role in glucocorticoid-induced osteoporosis
J Clin Endocrinol Metab, 95 (1), 246-55
DOI 10.1210/jc.2009-0595, PubMed 19875485

Lekva T, Bollerslev J, Kristo CL, Olstad OK, Ueland T, Jemtland R (2009)
The Glucocorticoid-Induced Leucine Zipper Gene (GILZ) Expression Decreases after Successful Treatment of Patients with Endogenous Cushing's Syndrome and May Play a Role in Glucocorticoid-Induced Osteoporosis
Endocr Rev, 30 (7), 932
DOI 10.1210/edrv.30.7.9985, PubMed 28199557

Lund PK, Øvstebø R, Møller AS, Olstad OK, Landsverk KS, Hellum M, Kierulf P (2009)
Using global gene expression patterns to characterize Annexin V positive and negative human monocytes in culture
Scand J Clin Lab Invest, 69 (2), 251-64
DOI 10.1080/00365510802499399, PubMed 18951241

Reppe S, Refvem H, Gautvik VT, Olstad OK, Høvring PI, Reinholt FP, Holden M, Frigessi A, Jemtland R, Gautvik KM (2009)
Eight genes are highly associated with BMD variation in postmenopausal Caucasian women
Bone, 46 (3), 604-12
DOI 10.1016/j.bone.2009.11.007, PubMed 19922823

Reseland JE, Reppe S, Olstad OK, Hjorth-Hansen H, Brenne AT, Syversen U, Waage A, Iversen PO (2009)
Abnormal adipokine levels and leptin-induced changes in gene expression profiles in multiple myeloma
Eur J Haematol, 83 (5), 460-70
DOI 10.1111/j.1600-0609.2009.01311.x, PubMed 19572994

Selmer KK, Brandal K, Olstad OK, Birkenes B, Undlien DE, Egeland T (2009)
Genome-wide linkage analysis with clustered SNP markers
J Biomol Screen, 14 (1), 92-6
DOI 10.1177/1087057108327327, PubMed 19171925

Utheim TP, Raeder S, Olstad OK, Utheim ØA, de La Paz M, Cheng R, Huynh TT, Messelt E, Roald B, Lyberg T (2009)
Comparison of the histology, gene expression profile, and phenotype of cultured human limbal epithelial cells from different limbal regions
Invest Ophthalmol Vis Sci, 50 (11), 5165-72
DOI 10.1167/iovs.08-2884, PubMed 19578011

Publications 2008

Ovstebø R, Olstad OK, Brusletto B, Møller AS, Aase A, Haug KB, Brandtzaeg P, Kierulf P (2008)
Identification of genes particularly sensitive to lipopolysaccharide (LPS) in human monocytes induced by wild-type versus LPS-deficient Neisseria meningitidis strains
Infect Immun, 76 (6), 2685-95
DOI 10.1128/IAI.01625-07, PubMed 18362127

Rødland EK, Mattingsdal M, Olstad OK, Ovstebø R, Kierulf P, Muller F, Frøland SS (2008)
Expression of genes in normal human monocytes in response to Aspergillus fumigatus
Med Mycol, 46 (4), 327-36
DOI 10.1080/13693780701874507, PubMed 18415839

Publications 2007

Reppe S, Stilgren L, Abrahamsen B, Olstad OK, Cero F, Brixen K, Nissen-Meyer LS, Gautvik KM (2007)
Abnormal muscle and hematopoietic gene expression may be important for clinical morbidity in primary hyperparathyroidism
Am J Physiol Endocrinol Metab, 292 (5), E1465-73
DOI 10.1152/ajpendo.00487.2006, PubMed 17227961

Publications 2006

Piehler AP, Wenzel JJ, Olstad OK, Haug KB, Kierulf P, Kaminski WE (2006)
The human ortholog of the rodent testis-specific ABC transporter Abca17 is a ubiquitously expressed pseudogene (ABCA17P) and shares a common 5' end with ABCA3
BMC Mol Biol, 7, 28
DOI 10.1186/1471-2199-7-28, PubMed 16968533

Reppe S, Stilgren L, Olstad OK, Brixen K, Nissen-Meyer LS, Gautvik KM, Abrahamsen B (2006)
Gene expression profiles give insight into the molecular pathology of bone in primary hyperparathyroidism
Bone, 39 (1), 189-98
DOI 10.1016/j.bone.2005.12.020, PubMed 16516570

Publications 2005

Fjeldheim AK, Høvring PI, Løseth OP, Johansen PW, Glover JC, Matre V, Olstad OK, Reppe S, Gordeladze JO, Walaas SI, Gautvik KM (2005)
Thyrotrophin-releasing hormone receptor 1 and prothyrotrophin-releasing hormone mRNA expression in the central nervous system are regulated by suckling in lactating rats
Eur J Endocrinol, 152 (5), 791-803
DOI 10.1530/eje.1.01902, PubMed 15879366

Publications 2004

Reppe S, Olstad OK, Rian E, Gautvik VT, Gautvik KM, Jemtland R (2004)
Butyrate response factor 1 is regulated by parathyroid hormone and bone morphogenetic protein-2 in osteoblastic cells
Biochem Biophys Res Commun, 324 (1), 218-23
DOI 10.1016/j.bbrc.2004.09.030, PubMed 15465005

Publications 2003

Olstad OK, Gautvik VT, Reppe S, Rian E, Jemtland R, Ohlsson C, Bruland OS, Gautvik KM (2003)
Molecular heterogeneity in human osteosarcoma demonstrated by enriched mRNAs isolated by directional tag PCR subtraction cloning
Anticancer Res, 23 (3B), 2201-16
PubMed 12894494

Publications 2000

Reppe S, Rian E, Jemtland R, Olstad OK, Gautvik VT, Gautvik KM (2000)
Sox-4 messenger RNA is expressed in the embryonic growth plate and regulated via the parathyroid hormone/parathyroid hormone-related protein receptor in osteoblast-like cells
J Bone Miner Res, 15 (12), 2402-12
DOI 10.1359/jbmr.2000.15.12.2402, PubMed 11127205

Publications 1999

Jemtland R, Rian E, Olstad OK, Haug E, Bruland OS, Bucht E, Gautvik KM (1999)
Two human osteoblast-like osteosarcoma cell lines show distinct expression and differential regulation of parathyroid hormone-related protein
J Bone Miner Res, 14 (6), 904-14
DOI 10.1359/jbmr.1999.14.6.904, PubMed 10352098

Publications 1997

Olstad OK, Reppe S, Loseth OP, Jemtland R, Gautvik KM (1997)
Binding and cyclic AMP stimulation by N-terminally deleted human PTHs (3-84 and 4-84) in a homologous ligand receptor system
J Bone Miner Res, 12 (9), 1348-57
DOI 10.1359/jbmr.1997.12.9.1348, PubMed 9286750

Publications 1995

Mathavan S, Gautvik VT, Rokkones E, Olstad OK, Kareem BN, Maeda S, Gautvik KM (1995)
High-level production of human parathyroid hormone in Bombyx mori larvae and BmN cells using recombinant baculovirus
Gene, 167 (1-2), 33-9
DOI 10.1016/0378-1119(95)00599-4, PubMed 8566802

Olstad OK (1995)
Expression, purification and characterization of recombinant parathyroid hormone like peptides
Norwegian Cances Society : Institute of Medical Biochemistry, University of Oslo, [Oslo], 1 b. (flere pag.)
BIBSYS 951330535, ISBN 82-91061-61-0

Olstad OK, Jemtland R, Loseth OP, Bringhurst FR, Gautvik KM (1995)
Expression and characterization of a recombinant human parathyroid hormone partial agonist with antagonistic properties: Gly-hPTH(-1-->+84)
Peptides, 16 (6), 1031-7
DOI 10.1016/0196-9781(95)00069-v, PubMed 8532584

Rokkones E, Fromm SH, Kareem BN, Klungland H, Olstad OK, Hogset A, Iversen J, Bjoro K, Gautvik KM (1995)
Human parathyroid hormone as a secretory peptide in milk of transgenic mice
J Cell Biochem, 59 (2), 168-76
DOI 10.1002/jcb.240590206, PubMed 8904311

Publications 1994

Olstad OK, Morrison NE, Jemtland R, Jüppner H, Segre GV, Gautvik KM (1994)
Differences in binding affinities of human PTH(1-84) do not alter biological potency: a comparison between chemically synthesized hormone, natural and mutant forms
Peptides, 15 (7), 1261-5
DOI 10.1016/0196-9781(94)90151-1, PubMed 7854979

Rian E, Jemtland R, Olstad OK, Endresen MJ, Grasser WA, Thiede MA, Henriksen T, Bucht E, Gautvik KM (1994)
Parathyroid hormone-related protein is produced by cultured endothelial cells: a possible role in angiogenesis
Biochem Biophys Res Commun, 198 (2), 740-7
DOI 10.1006/bbrc.1994.1107, PubMed 7507670

Rokkones E, Kareem BN, Olstad OK, Høgset A, Schenstrøm K, Hansson L, Gautvik KM (1994)
Expression of human parathyroid hormone in mammalian cells, Escherichia coli and Saccharomyces cerevisiae
J Biotechnol, 33 (3), 293-306
DOI 10.1016/0168-1656(94)90077-9, PubMed 7764740

Walaas SI, Czernik AJ, Olstad OK, Sletten K, Walaas O (1994)
Protein kinase C and cyclic AMP-dependent protein kinase phosphorylate phospholemman, an insulin and adrenaline-regulated membrane phosphoprotein, at specific sites in the carboxy terminal domain
Biochem J, 304 ( Pt 2) (Pt 2), 635-40
DOI 10.1042/bj3040635, PubMed 7999001

Publications 1993

Rian E, Jemtland R, Olstad OK, Gordeladze JO, Gautvik KM (1993)
Synthesis of human parathyroid-hormone-related protein(1-141) in Saccharomyces cerevisiae. A correct amino-terminal processing vital for the hormone's biological activity is obtained by an ubiquitin fusion protein approach
Eur J Biochem, 213 (1), 641-8
DOI 10.1111/j.1432-1033.1993.tb17803.x, PubMed 8386631

Publications 1992

Olstad OK, Reppe S, Gabrielsen OS, Hartmanis M, Blingsmo OR, Gautvik VT, Haflan AK, Christensen TB, Oyen TB, Gautvik KM (1992)
Isolation and characterization of two biologically active O-glycosylated forms of human parathyroid hormone produced in Saccharomyces cerevisiae. Identification of a new motif for O-glycosylation
Eur J Biochem, 205 (1), 311-9
DOI 10.1111/j.1432-1033.1992.tb16782.x, PubMed 1555591

Publications 1991

Reppe S, Gabrielsen OS, Olstad OK, Morrison N, Saether O, Blingsmo OR, Gautvik VT, Gordeladze J, Haflan AK, Voelkel EF (1991)
Characterization of a K26Q site-directed mutant of human parathyroid hormone expressed in yeast
J Biol Chem, 266 (22), 14198-201
PubMed 1860837

Publications 1983

Sletten K, Westermark P, Pitkänen P, Thyresson N, Olstad OK (1983)
Amino acid sequences in amyloid proteins of kappa III immunoglobulin light-chain origin
Scand J Immunol, 18 (6), 557-60
DOI 10.1111/j.1365-3083.1983.tb00891.x, PubMed 6665525