Hans Christian Dalsbotten Aass
- Leader of the Flow cytometry core facility, OUS, Ullevål; PhD
- +47 22 11 94 83 / 986 99 302
Publications 2024
Heritability of tear fluid cytokines in healthy twins
Ocul Surf, 32, 145-153
DOI 10.1016/j.jtos.2024.02.005, PubMed 38387783
Novel biomarkers in patients with uncontrolled hypertension with and without kidney damage
Blood Press, 33 (1), 2323980
DOI 10.1080/08037051.2024.2323980, PubMed 38606688
Changes in pain during a depressive episode and relationship to cytokine levels in major depressive disorder
Nord J Psychiatry, 78 (3), 181-188
DOI 10.1080/08039488.2023.2290654, PubMed 38251060
Proton- compared to X-irradiation leads to more acinar atrophy and greater hyposalivation accompanied by a differential cytokine response
Sci Rep, 14 (1), 22311
DOI 10.1038/s41598-024-73110-7, PubMed 39333378
Tear cytokine levels are reduced in patients treated with intravitreal injections
Ocul Surf, 32, 222-226
DOI 10.1016/j.jtos.2024.03.004, PubMed 38490478
Citalopram exposure of hESCs during neuronal differentiation identifies dysregulated genes involved in neurodevelopment and depression
Front Cell Dev Biol, 12, 1428538
DOI 10.3389/fcell.2024.1428538, PubMed 39055655
Publications 2023
Ocular Surface Homeostasis After Scleral Lens Usage
Eye Contact Lens, 49 (11), 459-463
DOI 10.1097/ICL.0000000000001027, PubMed 37651199
Cytokine Patterns as Predictors of Antibiotic Treatment Effect in Chronic Low Back Pain with Modic Changes: Subgroup Analyses of a Randomized Trial (AIM Study)
J Pain Res, 16, 1713-1724
DOI 10.2147/JPR.S406079, PubMed 37252109
Non-Coding RNA in Salivary Extracellular Vesicles: A New Frontier in Sjögren's Syndrome Diagnostics?
Int J Mol Sci, 24 (17)
DOI 10.3390/ijms241713409, PubMed 37686214
Longitudinal changes of serum cytokines in patients with chronic low back pain and Modic changes
Osteoarthritis Cartilage, 31 (4), 543-547
DOI 10.1016/j.joca.2023.01.001, PubMed 36640896
Isolation, characterization, and fibroblast uptake of bacterial extracellular vesicles from Porphyromonas gingivalis strains
Microbiologyopen, 12 (5), e1388
DOI 10.1002/mbo3.1388, PubMed 37877660
Treatment cessation in HBeAg-negative chronic hepatitis B: clinical response is associated with increase in specific proinflammatory cytokines
Sci Rep, 13 (1), 22590
DOI 10.1038/s41598-023-50216-y, PubMed 38114718
Association of pro-inflammatory cytokines with trauma and post-traumatic stress disorder visiting a tertiary care hospital in Kathmandu
PLoS One, 18 (2), e0281125
DOI 10.1371/journal.pone.0281125, PubMed 36730263
Cytokine Levels in Saliva Are Associated with Salivary Gland Fibrosis and Hyposalivation in Mice after Fractionated Radiotherapy of the Head and Neck
Int J Mol Sci, 24 (20)
DOI 10.3390/ijms242015218, PubMed 37894899
Publications 2022
Serum Amyloidogenic Nanoplaques and Cytokines in Alzheimer's Disease: Pilot Study in a Small Naturalistic Memory Clinic Cohort
J Alzheimers Dis, 86 (3), 1459-1470
DOI 10.3233/JAD-215504, PubMed 35213378
Associations between patient-reported late effects and systemic cytokines in long-term survivors of head and neck cancer treated with radiotherapy
J Cancer Surviv, 17 (4), 1082-1093
DOI 10.1007/s11764-022-01273-1, PubMed 36350483
Change in Ocular Surface Staining during Eyelid Warming Is Related to Tear Cytokine Levels
J Ophthalmol, 2022, 5103231
DOI 10.1155/2022/5103231, PubMed 35967518
A Cease in Shift Work Reverses Arterial Stiffness but Increases Weight and Glycosylated Hemoglobin A 5-Month Follow-Up in Industry
J Cardiovasc Dev Dis, 9 (6)
DOI 10.3390/jcdd9060190, PubMed 35735819
Influence of Shift Work on Arterial Stiffness and Systemic Inflammation: A 3-Year Follow-up Study in Industry
J Occup Environ Med, 65 (4), 284-291
DOI 10.1097/JOM.0000000000002779, PubMed 36576877
Abnormal Cytokines in Trauma Patients Explained by Obesity, Musculoskeletal Disease, Smoking, and Lung Disease
Neuropsychobiology, 81 (6), 516-530
DOI 10.1159/000526806, PubMed 36302340
Publications 2021
Associations of cerebrospinal fluid amyloidogenic nanoplaques with cytokines in Alzheimer's disease
Transl Neurodegener, 10 (1), 18
DOI 10.1186/s40035-021-00244-3, PubMed 34099032
Uptake of circulating extracellular vesicles from rectal cancer patients and differential responses by human monocyte cultures
FEBS Open Bio, 11 (3), 724-740
DOI 10.1002/2211-5463.13098, PubMed 33512765
Macrophage migration inhibitory factor: a potential biomarker for chronic low back pain in patients with Modic changes
RMD Open, 7 (2)
DOI 10.1136/rmdopen-2021-001726, PubMed 34344830
Plasma LOX-Products and Monocyte Signaling Is Reduced by Adjunctive Cyclooxygenase-2 Inhibitor in a Phase I Clinical Trial of Tuberculosis Patients
Front Cell Infect Microbiol, 11, 669623
DOI 10.3389/fcimb.2021.669623, PubMed 34307194
The Silk Protein Sericin Promotes Viability of ARPE-19 and Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelial Cells in vitro
Curr. Eye Res., 46 (4), 504-514
DOI 10.1080/02713683.2020.1809001
Plasma extracellular vesicles in people living with HIV and type 2 diabetes are related to microbial translocation and cardiovascular risk
Sci Rep, 11 (1), 21936
DOI 10.1038/s41598-021-01334-y, PubMed 34754007
Interleukin-6 in Critical Coronavirus Disease 2019, a Driver of Lung Inflammation of Systemic Origin?
Crit Care Explor, 3 (10), e0542
DOI 10.1097/CCE.0000000000000542, PubMed 34604785
Publications 2020
Cytokines Explored in Saliva and Tears from Radiated Cancer Patients Correlate with Clinical Manifestations, Influencing Important Immunoregulatory Cellular Pathways
Cells, 9 (9)
DOI 10.3390/cells9092050, PubMed 32911805
The Effects of Prolonged Storage on ARPE-19 Cells Stored at Three Different Storage Temperatures
Molecules, 25 (24)
DOI 10.3390/molecules25245809, PubMed 33317020
The Silk Protein Sericin Promotes Viability of ARPE-19 and Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelial Cells in vitro
Curr Eye Res, 46 (4), 504-514
DOI 10.1080/02713683.2020.1809001, PubMed 32777180
Cardiovascular Health Effects of Shift Work with Long Working Hours and Night Shifts: Study Protocol for a Three-Year Prospective Follow-Up Study on Industrial Workers
Int J Environ Res Public Health, 17 (2)
DOI 10.3390/ijerph17020589, PubMed 31963313
Publications 2019
Transcriptomes of antigen presenting cells in human thymus
PLoS One, 14 (7), e0218858
DOI 10.1371/journal.pone.0218858, PubMed 31261375
Shift Work Including Night Work and Long Working Hours in Industrial Plants Increases the Risk of Atherosclerosis
Int J Environ Res Public Health, 16 (3)
DOI 10.3390/ijerph16030521, PubMed 30759884
Activated dendritic cells and monocytes in HIV immunological nonresponders: HIV-induced interferon-inducible protein-10 correlates with low future CD4+ recovery
AIDS, 33 (7), 1117-1129
DOI 10.1097/QAD.0000000000002173, PubMed 30789356
Publications 2018
Efficient extracellular vesicle isolation by combining cell media modifications, ultrafiltration, and size-exclusion chromatography
PLoS One, 13 (9), e0204276
DOI 10.1371/journal.pone.0204276, PubMed 30260987
The Level of Inflammatory Tear Cytokines is Elevated in Congenital Aniridia and Associated with Meibomian Gland Dysfunction
Invest Ophthalmol Vis Sci, 59 (5), 2197-2204
DOI 10.1167/iovs.18-24027, PubMed 29801153
Systemic and Airway Inflammation after Exposure to Fumes from Military Small Arms
Am J Respir Crit Care Med, 197 (10), 1349-1353
DOI 10.1164/rccm.201709-1857LE, PubMed 29144885
The Effect of a Leisure Time Physical Activity Intervention Delivered via a Workplace: 15-Month Follow-Up Study
Int J Environ Res Public Health, 15 (2)
DOI 10.3390/ijerph15020264, PubMed 29401699
Chronic fatigue is highly prevalent in survivors of autologous stem cell transplantation and associated with IL-6, neuroticism, cardiorespiratory fitness, and obesity
Bone Marrow Transplant, 54 (4), 607-610
DOI 10.1038/s41409-018-0342-y, PubMed 30262906
Whole-blood incubation with the Neisseria meningitidis lpxL1 mutant induces less pro-inflammatory cytokines than the wild type, and IL-10 reduces the MyD88-dependent cytokines
Innate Immun, 24 (2), 101-111
DOI 10.1177/1753425917749299, PubMed 29313733
Publications 2017
Physical activity initiated by employer induces improvements in a novel set of biomarkers of inflammation: an 8-week follow-up study
Eur J Appl Physiol, 117 (3), 521-532
DOI 10.1007/s00421-016-3533-5, PubMed 28185008
Bronchial wheezing predicts inflammation and respiratory failure in fire smoke victims
Acta Anaesthesiol Scand, 61 (9), 1142-1154
DOI 10.1111/aas.12962, PubMed 28832892
A Double-Blinded Randomized Study Investigating a Possible Anti-Inflammatory Effect of Saxagliptin versus Placebo as Add-On Therapy in Patients with Both Type 2 Diabetes And Stable Coronary Artery Disease
Mediators Inflamm, 2017, 5380638
DOI 10.1155/2017/5380638, PubMed 28596642
Publications 2016
Cytokine Profile in Autism Spectrum Disorders in Children
J Mol Neurosci, 61 (1), 1-7
DOI 10.1007/s12031-016-0847-z, PubMed 27730473
Recovery from major depressive disorder episode after non-pharmacological treatment is associated with normalized cytokine levels
Acta Psychiatr Scand, 134 (1), 40-7
DOI 10.1111/acps.12576, PubMed 27028967
Cell type specific DNA methylation in cord blood: A 450K-reference data set and cell count-based validation of estimated cell type composition
Epigenetics, 11 (9), 690-698
DOI 10.1080/15592294.2016.1214782, PubMed 27494297
Cytokine Changes following Acute Ethanol Intoxication in Healthy Men: A Crossover Study
Mediators Inflamm, 2016, 3758590
DOI 10.1155/2016/3758590, PubMed 28090151
Publications 2015
Effect of Storage Temperature on the Phenotype of Cultured Epidermal Cells Stored in Xenobiotic-Free Medium
Curr Eye Res, 41 (6), 757-68
DOI 10.3109/02713683.2015.1062113, PubMed 26398483
Recovery of plasma vascular endothelial growth factor concentrations during aflibercept loading phase and after the transition to bimonthly treatment for neovascular age-related macular degeneration
Br J Ophthalmol, 99 (12), 1610-3
DOI 10.1136/bjophthalmol-2015-306781, PubMed 25966740
Publications 2014
The plasma levels of various cytokines are increased during ongoing depression and are reduced to normal levels after recovery
Psychoneuroendocrinology, 45, 77-86
DOI 10.1016/j.psyneuen.2014.03.019, PubMed 24845179
Publications 2013
Transcriptional profiling of mRNAs and microRNAs in human bone marrow precursor B cells identifies subset- and age-specific variations
PLoS One, 8 (7), e70721
DOI 10.1371/journal.pone.0070721, PubMed 23936243
Increased ID2 levels in adult precursor B cells as compared with children is associated with impaired Ig locus contraction and decreased bone marrow output
J Immunol, 191 (3), 1210-9
DOI 10.4049/jimmunol.1203462, PubMed 23825313
Boosters of a therapeutic HIV-1 vaccine induce divergent T cell responses related to regulatory mechanisms
Vaccine, 31 (41), 4611-8
DOI 10.1016/j.vaccine.2013.07.037, PubMed 23906886
Inflammation-induced catabolism of tryptophan and tyrosine in acute ischemic stroke
J Mol Neurosci, 51 (3), 893-902
DOI 10.1007/s12031-013-0097-2, PubMed 23990339
Microparticle-associated tissue factor activity is reduced by inhibition of the complement protein 5 in Neisseria meningitidis-exposed whole blood
Innate Immun, 20 (5), 552-60
DOI 10.1177/1753425913502099, PubMed 24051102
Publications 2012
Global effect of interleukin-10 on the transcriptional profile induced by Neisseria meningitidis in human monocytes
Infect Immun, 80 (11), 4046-54
DOI 10.1128/IAI.00386-12, PubMed 22966040
Serum levels of cytokines, glucose, and hemoglobin as possible predictors of poststroke depression, and association with poststroke fatigue
Int J Neurosci, 122 (11), 682-90
DOI 10.3109/00207454.2012.709892, PubMed 22812657
Serum cytokine and glucose levels as predictors of poststroke fatigue in acute ischemic stroke patients (vol 258, pg 670, 2011)
J. Neurol., 259 (2), 399
DOI 10.1007/s00415-011-6332-2
Serum levels of cytokines and C-reactive protein in acute ischemic stroke patients, and their relationship to stroke lateralization, type, and infarct volume (vol 258, pg 677, 2011)
J. Neurol., 259 (2), 400
DOI 10.1007/s00415-011-6333-1
Publications 2011
Anticoagulant effects of an antidiabetic drug on monocytes in vitro
Thromb Res, 128 (5), e100-6
DOI 10.1016/j.thromres.2011.07.007, PubMed 21862110
Serum cytokine and glucose levels as predictors of poststroke fatigue in acute ischemic stroke patients
J Neurol, 258 (4), 670-6
DOI 10.1007/s00415-011-5962-8, PubMed 21365457
Serum levels of cytokines and C-reactive protein in acute ischemic stroke patients, and their relationship to stroke lateralization, type, and infarct volume
J Neurol, 258 (4), 677-85
DOI 10.1007/s00415-011-6006-0, PubMed 21424610
LPS from Neisseria meningitidis is crucial for inducing monocyte- and microparticle-associated tissue factor activity but not for tissue factor expression
Innate Immun, 18 (4), 580-91
DOI 10.1177/1753425911428230, PubMed 22180561
Fluorescent particles in the antibody solution result in false TF- and CD14-positive microparticles in flow cytometric analysis
Cytometry A, 79 (12), 990-9
DOI 10.1002/cyto.a.21147, PubMed 21990118
Publications 2009
Cardiomyocytes from postinfarction failing rat hearts have improved ischemia tolerance
Am J Physiol Heart Circ Physiol, 296 (3), H787-95
DOI 10.1152/ajpheart.00796.2008, PubMed 19136604
Publications 2007
Chromosomal 20q gain in the DNA diploid component of aneuploid colorectal carcinomas
Int J Cancer, 120 (12), 2734-8
DOI 10.1002/ijc.22537, PubMed 17354231
The 2-oxoacid dehydrogenase multi-enzyme complex of the archaeon Thermoplasma acidophilum - recombinant expression, assembly and characterization
FEBS J, 274 (20), 5406-15
DOI 10.1111/j.1742-4658.2007.06067.x, PubMed 17894823
CD59 efficiently protects human NT2-N neurons against complement-mediated damage
Scand J Immunol, 66 (2-3), 345-51
DOI 10.1111/j.1365-3083.2007.01959.x, PubMed 17635812
Analysis of the mechanism and regulation of lactose transport and metabolism in Clostridium acetobutylicum ATCC 824
Appl Environ Microbiol, 73 (6), 1842-50
DOI 10.1128/AEM.02082-06, PubMed 17209069
Publications 2006
Are keratoacanthomas variants of squamous cell carcinomas? A comparison of chromosomal aberrations by comparative genomic hybridization
J Invest Dermatol, 126 (10), 2308-15
DOI 10.1038/sj.jid.5700375, PubMed 16728973