Reidun Øvstebø

  • Researcher; PhD
  • +47 22 11 94 91

Publications 2023

Brusletto BS, Hellerud BC, Øvstebø R, Brandtzaeg P (2023)
Neisseria meningitidis accumulate in large organs during meningococcal sepsis
Front Cell Infect Microbiol, 13, 1298360
DOI 10.3389/fcimb.2023.1298360, PubMed 38089821

Cross T, Haug KBF, Brusletto BS, Ommundsen SK, Trøseid AS, Aspelin T, Olstad OK, Aass HCD, Galtung HK, Utheim TP, Jensen JL, Øvstebø R (2023)
Non-Coding RNA in Salivary Extracellular Vesicles: A New Frontier in Sjögren's Syndrome Diagnostics?
Int J Mol Sci, 24 (17)
DOI 10.3390/ijms241713409, PubMed 37686214

Cross T, Øvstebø R, Brusletto BS, Trøseid AS, Olstad OK, Aspelin T, Jackson CJ, Chen X, Utheim TP, Haug KBF (2023)
RNA Profiles of Tear Fluid Extracellular Vesicles in Patients with Dry Eye-Related Symptoms
Int J Mol Sci, 24 (20)
DOI 10.3390/ijms242015390, PubMed 37895069

Haugsten HR, Kristoffersen AK, Haug TM, Søland TM, Øvstebø R, Aass HCD, Enersen M, Galtung HK (2023)
Isolation, characterization, and fibroblast uptake of bacterial extracellular vesicles from Porphyromonas gingivalis strains
Microbiologyopen, 12 (5), e1388
DOI 10.1002/mbo3.1388, PubMed 37877660

Aas V, Øvstebø R, Brusletto BS, Aspelin T, Trøseid AS, Qureshi S, Eid DSO, Olstad OK, Nyman TA, Haug KBF (2023)
Distinct microRNA and protein profiles of extracellular vesicles secreted from myotubes from morbidly obese donors with type 2 diabetes in response to electrical pulse stimulation
Front Physiol, 14, 1143966
DOI 10.3389/fphys.2023.1143966, PubMed 37064893

Publications 2022

Brusletto BS, Hellerud BC, Olstad OK, Øvstebø R, Brandtzaeg P (2022)
Transcriptomic changes in the large organs in lethal meningococcal shock are reflected in a porcine shock model
Front Cell Infect Microbiol, 12, 908204
DOI 10.3389/fcimb.2022.908204, PubMed 36034711

Publications 2021

Bjørnetrø T, Steffensen LA, Vestad B, Brusletto BS, Olstad OK, Trøseid AM, Aass HCD, Haug KBF, Llorente A, Bøe SO, Lång A, Samiappan R, Redalen KR, Øvstebø R, Ree AH (2021)
Uptake of circulating extracellular vesicles from rectal cancer patients and differential responses by human monocyte cultures
FEBS Open Bio, 11 (3), 724-740
DOI 10.1002/2211-5463.13098, PubMed 33512765

Vestad B, Nyman TA, Hove-Skovsgaard M, Stensland M, Hoel H, Trøseid AS, Aspelin T, Aass HCD, Puhka M, Hov JR, Nielsen SD, Øvstebø R, Trøseid M (2021)
Plasma extracellular vesicles in people living with HIV and type 2 diabetes are related to microbial translocation and cardiovascular risk
Sci Rep, 11 (1), 21936
DOI 10.1038/s41598-021-01334-y, PubMed 34754007

Publications 2020

Brusletto BS, Løberg EM, Hellerud BC, Goverud IL, Berg JP, Olstad OK, Gopinathan U, Brandtzaeg P, Øvstebø R (2020)
Extensive Changes in Transcriptomic "Fingerprints" and Immunological Cells in the Large Organs of Patients Dying of Acute Septic Shock and Multiple Organ Failure Caused by Neisseria meningitidis
Front Cell Infect Microbiol, 10, 42
DOI 10.3389/fcimb.2020.00042, PubMed 32154187

Guerreiro EM, Øvstebø R, Thiede B, Costea DE, Søland TM, Kanli Galtung H (2020)
Cancer cell line-specific protein profiles in extracellular vesicles identified by proteomics
PLoS One, 15 (9), e0238591
DOI 10.1371/journal.pone.0238591, PubMed 32886718

Lunde LK, Skare Ø, Mamen A, Sirnes PA, Aass HCD, Øvstebø R, Goffeng E, Matre D, Nielsen P, Heglum HSA, Hammer SE, Skogstad M (2020)
Cardiovascular Health Effects of Shift Work with Long Working Hours and Night Shifts: Study Protocol for a Three-Year Prospective Follow-Up Study on Industrial Workers
Int J Environ Res Public Health, 17 (2)
DOI 10.3390/ijerph17020589, PubMed 31963313

Mamen A, Øvstebø R, Sirnes PA, Nielsen P, Skogstad M (2020)
High-Intensity Training Reduces CVD Risk Factors among Rotating Shift Workers: An Eight-Week Intervention in Industry
Int J Environ Res Public Health, 17 (11)
DOI 10.3390/ijerph17113943, PubMed 32498373

Publications 2019

Aqrawi LA, Galtung HK, Guerreiro EM, Øvstebø R, Thiede B, Utheim TP, Chen X, Utheim ØA, Palm Ø, Skarstein K, Jensen JL (2019)
Proteomic and histopathological characterisation of sicca subjects and primary Sjögren's syndrome patients reveals promising tear, saliva and extracellular vesicle disease biomarkers
Arthritis Res Ther, 21 (1), 181
DOI 10.1186/s13075-019-1961-4, PubMed 31366407

Mihret W, Sletbakk Brusletto B, Øvstebø R, Siebke Troseid AM, Norheim G, Merid Y, Kassu A, Abebe W, Ayele S, Silamsaw Asres M, Yamuah L, Aseffa A, Petros B, Caugant DA, Brandtzaeg P (2019)
Molecular studies of meningococcal and pneumococcal meningitis patients in Ethiopia
Innate Immun, 25 (3), 158-167
DOI 10.1177/1753425918806363, PubMed 30894090

Skogstad M, Mamen A, Lunde LK, Ulvestad B, Matre D, Aass HCD, Øvstebø R, Nielsen P, Samuelsen KN, Skare Ø, Sirnes PA (2019)
Shift Work Including Night Work and Long Working Hours in Industrial Plants Increases the Risk of Atherosclerosis
Int J Environ Res Public Health, 16 (3)
DOI 10.3390/ijerph16030521, PubMed 30759884

Øya E, Solhaug A, Bølling AK, Øvstebø R, Steensen TB, Afanou AKJ, Holme JA (2019)
Pro-inflammatory responses induced by A. fumigatus and A. versicolor in various human macrophage models
J Toxicol Environ Health A, 82 (8), 483-501
DOI 10.1080/15287394.2019.1619114, PubMed 31116698

Publications 2018

Gopinathan U, Redalen KR, Trøseid AM, Kierulf P, Brandtzaeg P, Ree AH, Berg JP, Øvstebø R (2018)
Large-scale reduction of tyrosine kinase activities in human monocytes stimulated in vitro with N. meningitidis
PLoS One, 13 (1), e0181912
DOI 10.1371/journal.pone.0181912, PubMed 29357362

Guerreiro EM, Vestad B, Steffensen LA, Aass HCD, Saeed M, Øvstebø R, Costea DE, Galtung HK, Søland TM (2018)
Efficient extracellular vesicle isolation by combining cell media modifications, ultrafiltration, and size-exclusion chromatography
PLoS One, 13 (9), e0204276
DOI 10.1371/journal.pone.0204276, PubMed 30260987

Sikkeland LIB, Borander AK, Voie ØA, Aass HCD, Øvstebø R, Aukrust P, Longva K, Alexis NE, Kongerud J, Ueland T (2018)
Systemic and Airway Inflammation after Exposure to Fumes from Military Small Arms
Am J Respir Crit Care Med, 197 (10), 1349-1353
DOI 10.1164/rccm.201709-1857LE, PubMed 29144885

Øya E, Zegeye FD, Bølling AK, Øvstebø R, Afanou AKJ, Øvrevik J, Refsnes M, Holme JA (2018)
Hyphae fragments from A. fumigatus sensitize lung cells to silica particles (Min-U-Sil): Increased release of IL-1β
Toxicol In Vitro, 55, 1-10
DOI 10.1016/j.tiv.2018.11.002, PubMed 30414920

Aass HCD, Hellum M, Trøseid AS, Brandtzaeg P, Berg JP, Øvstebø R, Henriksson CE (2018)
Whole-blood incubation with the Neisseria meningitidis lpxL1 mutant induces less pro-inflammatory cytokines than the wild type, and IL-10 reduces the MyD88-dependent cytokines
Innate Immun, 24 (2), 101-111
DOI 10.1177/1753425917749299, PubMed 29313733

Publications 2017

Aqrawi LA, Galtung HK, Vestad B, Øvstebø R, Thiede B, Rusthen S, Young A, Guerreiro EM, Utheim TP, Chen X, Utheim ØA, Palm Ø, Jensen JL (2017)
Identification of potential saliva and tear biomarkers in primary Sjögren's syndrome, utilising the extraction of extracellular vesicles and proteomics analysis
Arthritis Res Ther, 19 (1), 14
DOI 10.1186/s13075-017-1228-x, PubMed 28122643

Brusletto BS, Hellerud BC, Løberg EM, Goverud IL, Vege Å, Berg JP, Brandtzaeg P, Øvstebø R (2017)
Traceability and distribution of Neisseria meningitidis DNA in archived post mortem tissue samples from patients with systemic meningococcal disease
BMC Clin Pathol, 17, 10
DOI 10.1186/s12907-017-0049-9, PubMed 28824331

Gopinathan U, Øvstebø R, Brusletto BS, Olstad OK, Kierulf P, Brandtzaeg P, Berg JP (2017)
Transcriptomic data from two primary cell models stimulating human monocytes suggest inhibition of oxidative phosphorylation and mitochondrial function by N. meningitidis which is partially up-regulated by IL-10
BMC Immunol, 18 (1), 46
DOI 10.1186/s12865-017-0229-5, PubMed 29078758

Hellum M, Franco-Lie I, Øvstebø R, Hauge T, Henriksson CE (2017)
The effect of corn trypsin inhibitor, anti-tissue factor pathway inhibitor antibodies and phospholipids on microvesicle-associated thrombin generation in patients with pancreatic cancer and healthy controls
PLoS One, 12 (9), e0184579
DOI 10.1371/journal.pone.0184579, PubMed 28910348

Njerve IU, Åkra S, Weiss TW, Solheim S, Øvstebø R, Aass HCD, Byrkjeland R, Arnesen H, Seljeflot I (2017)
A Double-Blinded Randomized Study Investigating a Possible Anti-Inflammatory Effect of Saxagliptin versus Placebo as Add-On Therapy in Patients with Both Type 2 Diabetes And Stable Coronary Artery Disease
Mediators Inflamm, 2017, 5380638
DOI 10.1155/2017/5380638, PubMed 28596642

Soares RP, Xander P, Costa AO, Marcilla A, Menezes-Neto A, Del Portillo H, Witwer K, Wauben M, Nolte-T Hoen E, Olivier M, Criado MF, da Silva LLP, Abdel Baqui MM, Schenkman S, Colli W, Alves MJM, Ferreira KS, Puccia R, Nejsum P, Riesbeck K, Stensballe A, Hansen EP, Jaular LM, Øvstebø R, de la Canal L et al. (2017)
Highlights of the São Paulo ISEV workshop on extracellular vesicles in cross-kingdom communication
J Extracell Vesicles, 6 (1), 1407213
DOI 10.1080/20013078.2017.1407213, PubMed 30044885

Vestad B, Llorente A, Neurauter A, Phuyal S, Kierulf B, Kierulf P, Skotland T, Sandvig K, Haug KBF, Øvstebø R (2017)
Size and concentration analyses of extracellular vesicles by nanoparticle tracking analysis: a variation study
J Extracell Vesicles, 6 (1), 1344087
DOI 10.1080/20013078.2017.1344087, PubMed 28804597

Publications 2016

Hellum M, Trøseid AS, Berg JP, Brandtzaeg P, Øvstebø R, Henriksson CE (2016)
The Neisseria meningitidis lpxL1 mutant induces less tissue factor expression and activity in primary human monocytes and monocyte-derived microvesicles than the wild type meningococcus
Innate Immun, 23 (2), 196-205
DOI 10.1177/1753425916684201, PubMed 28024455

Skogstad M, Lunde LK, Skare Ø, Mamen A, Alfonso JH, Øvstebø R, Ulvestad B (2016)
Physical activity initiated by employer and its health effects; an eight week follow-up study
BMC Public Health, 16, 377
DOI 10.1186/s12889-016-3035-8, PubMed 27146485

Stylianou E, Ueland T, Borchsenius F, Michelsen AE, Øvstebø R, Mollnes TE, Skjønsberg OH, Aukrust P (2016)
Specific allergen immunotherapy: effect on IgE, IgG4 and chemokines in patients with allergic rhinitis
Scand J Clin Lab Invest, 76 (2), 118-27
DOI 10.3109/00365513.2015.1110856, PubMed 26878875

Publications 2014

Gopinathan U, Brusletto BS, Olstad OK, Kierulf P, Berg JP, Brandtzaeg P, Øvstebø R (2014)
IL-10 immunodepletion from meningococcal sepsis plasma induces extensive changes in gene expression and cytokine release in stimulated human monocytes
Innate Immun, 21 (4), 429-49
DOI 10.1177/1753425914547743, PubMed 25233959

Publications 2013

Hellum M, Øvstebø R, Brusletto BS, Berg JP, Brandtzaeg P, Henriksson CE (2013)
Microparticle-associated tissue factor activity correlates with plasma levels of bacterial lipopolysaccharides in meningococcal septic shock
Thromb Res, 133 (3), 507-14
DOI 10.1016/j.thromres.2013.12.031, PubMed 24423888

Øvstebø R, Hellum M, Aass HC, Trøseid AM, Brandtzaeg P, Mollnes TE, Henriksson CE (2013)
Microparticle-associated tissue factor activity is reduced by inhibition of the complement protein 5 in Neisseria meningitidis-exposed whole blood
Innate Immun, 20 (5), 552-60
DOI 10.1177/1753425913502099, PubMed 24051102

Publications 2012

Dahm AE, Eilertsen AL, Goeman J, Olstad OK, Ovstebø R, Kierulf P, Mowinckel MC, Skretting G, Sandset PM (2012)
A microarray study on the effect of four hormone therapy regimens on gene transcription in whole blood from healthy postmenopausal women
Thromb Res, 130 (1), 45-51
DOI 10.1016/j.thromres.2011.12.009, PubMed 22217510

Gopinathan U, Ovstebø R, Olstad OK, Brusletto B, Dalsbotten Aass HC, Kierulf P, Brandtzaeg P, Berg JP (2012)
Global effect of interleukin-10 on the transcriptional profile induced by Neisseria meningitidis in human monocytes
Infect Immun, 80 (11), 4046-54
DOI 10.1128/IAI.00386-12, PubMed 22966040

Hellum M, Øvstebø R, Trøseid AM, Berg JP, Brandtzaeg P, Henriksson CE (2012)
Microparticle-associated tissue factor activity measured with the Zymuphen MP-TF kit and the calibrated automated thrombogram assay
Blood Coagul Fibrinolysis, 23 (6), 520-6
DOI 10.1097/MBC.0b013e328354a256, PubMed 22732249

Publications 2011

Fell AK, Notø H, Skogstad M, Nordby KC, Eduard W, Svendsen MV, Ovstebø R, Trøseid AM, Kongerud J (2011)
A cross-shift study of lung function, exhaled nitric oxide and inflammatory markers in blood in Norwegian cement production workers
Occup Environ Med, 68 (11), 799-805
DOI 10.1136/oem.2010.057729, PubMed 21297153

Henriksson CE, Hellum M, Haug KB, Aass HC, Joø GB, Øvstebø R, Trøseid AM, Klingenberg O, Kierulf P (2011)
Anticoagulant effects of an antidiabetic drug on monocytes in vitro
Thromb Res, 128 (5), e100-6
DOI 10.1016/j.thromres.2011.07.007, PubMed 21862110

Opstad TB, Pettersen AA, Weiss TW, Akra S, Øvstebø R, Arnesen H, Seljeflot I (2011)
Genetic variation, gene-expression and circulating levels of matrix metalloproteinase-9 in patients with stable coronary artery disease
Clin Chim Acta, 413 (1-2), 113-20
DOI 10.1016/j.cca.2011.09.004, PubMed 21963461

Skogstad M, Sikkeland LI, Øvstebø R, Haug KB, Heldal KK, Skare Ø, Kongerud J, Kierulf P, Eduard W (2011)
Long-term occupational outcomes of endotoxin exposure and the effect of exposure cessation
Occup Environ Med, 69 (2), 107-12
DOI 10.1136/oem.2010.062414, PubMed 21810928

Øvstebø R, Aass HC, Haug KB, Trøseid AM, Gopinathan U, Kierulf P, Berg JP, Brandtzaeg P, Henriksson CE (2011)
LPS from Neisseria meningitidis is crucial for inducing monocyte- and microparticle-associated tissue factor activity but not for tissue factor expression
Innate Immun, 18 (4), 580-91
DOI 10.1177/1753425911428230, PubMed 22180561

Aass HC, Øvstebø R, Trøseid AM, Kierulf P, Berg JP, Henriksson CE (2011)
Fluorescent particles in the antibody solution result in false TF- and CD14-positive microparticles in flow cytometric analysis
Cytometry A, 79 (12), 990-9
DOI 10.1002/cyto.a.21147, PubMed 21990118

Publications 2010

Piehler AP, Grimholt RM, Ovstebø R, Berg JP (2010)
Gene expression results in lipopolysaccharide-stimulated monocytes depend significantly on the choice of reference genes
BMC Immunol, 11, 21
DOI 10.1186/1471-2172-11-21, PubMed 20441576

Publications 2009

Lund PK, Øvstebø R, Møller AS, Olstad OK, Landsverk KS, Hellum M, Kierulf P (2009)
Using global gene expression patterns to characterize Annexin V positive and negative human monocytes in culture
Scand J Clin Lab Invest, 69 (2), 251-64
DOI 10.1080/00365510802499399, PubMed 18951241

Publications 2008

Ovstebø R, Olstad OK, Brusletto B, Møller AS, Aase A, Haug KB, Brandtzaeg P, Kierulf P (2008)
Identification of genes particularly sensitive to lipopolysaccharide (LPS) in human monocytes induced by wild-type versus LPS-deficient Neisseria meningitidis strains
Infect Immun, 76 (6), 2685-95
DOI 10.1128/IAI.01625-07, PubMed 18362127

Rojahn A, Brusletto B, Øvstebø R, Haug KB, Kierulf P, Brandtzaeg P (2008)
Does granulocyte colony-stimulating factor ameliorate the proinflammatory response in human meningococcal septic shock?
Crit Care Med, 36 (9), 2583-9
DOI 10.1097/CCM.0b013e3181844399, PubMed 18679115

Rødland EK, Mattingsdal M, Olstad OK, Ovstebø R, Kierulf P, Muller F, Frøland SS (2008)
Expression of genes in normal human monocytes in response to Aspergillus fumigatus
Med Mycol, 46 (4), 327-36
DOI 10.1080/13693780701874507, PubMed 18415839

Øvstebø R (2008)
Quantification of nucleic acids (mRNA and DNA) in human biological materials: methodological considerations and clinical applications
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 642, 1 b. (flere pag.)
BIBSYS 081145012, ISBN 978-82-8072-901-9

Publications 2007

Sikkeland LI, Skogstad M, Ovstebø R, Brusletto B, Haug KB, Kongerud J, Eduard W, Kierulf P (2007)
Circulating lipopolysaccharides in the blood from "bioprotein" production workers
Occup Environ Med, 65 (3), 211-4
DOI 10.1136/oem.2007.032938, PubMed 17855504

Øvstebø R, Lande K, Kierulf P, Haug KB (2007)
Quantification of relative changes in specific mRNAs from frozen whole blood - methodological considerations and clinical implications
Clin Chem Lab Med, 45 (2), 171-6
DOI 10.1515/CCLM.2007.035, PubMed 17311503

Publications 2005

Henriksson CE, Klingenberg O, Ovstebø R, Joø GB, Westvik AB, Kierulf P (2005)
Discrepancy between tissue factor activity and tissue factor expression in endotoxin-induced monocytes is associated with apoptosis and necrosis
Thromb Haemost, 94 (6), 1236-44
DOI 10.1160/TH05-07-0463, PubMed 16411400

Møller AS, Ovstebø R, Haug KB, Joø GB, Westvik AB, Kierulf P (2005)
Chemokine production and pattern recognition receptor (PRR) expression in whole blood stimulated with pathogen-associated molecular patterns (PAMPs)
Cytokine, 32 (6), 304-15
DOI 10.1016/j.cyto.2005.11.008, PubMed 16406558

Ovstebo R, Brandtzaeg P, Brusletto B, Haug KBF, Lande K, Hoiby EA, Kierulf P (2005)
Use of robotized DNA isolation and real-time PCR to quantify and identify close correlation between levels of Neisseria meningitidis DNA and lipopolysaccharides in plasma and cerebrospinal fluid from patients with systemic meningococcal disease (vol 42, pg 2980, 2004)
J. Clin. Microbiol., 43 (1), 532
DOI 10.1128/JCM.43.1.532.2005

Publications 2004

Øvstebø R, Brandtzaeg P, Brusletto B, Haug KB, Lande K, Høiby EA, Kierulf P (2004)
Use of robotized DNA isolation and real-time PCR to quantify and identify close correlation between levels of Neisseria meningitidis DNA and lipopolysaccharides in plasma and cerebrospinal fluid from patients with systemic meningococcal disease
J Clin Microbiol, 42 (7), 2980-7
DOI 10.1128/JCM.42.7.2980-2987.2004, PubMed 15243048

Publications 2003

Bjerre A, Brusletto B, Øvstebø R, Joø GB, Kierulf P, Brandtzaeg P (2003)
Identification of meningococcal LPS as a major monocyte activator in IL-10 depleted shock plasmas and CSF by blocking the CD14-TLR4 receptor complex
J Endotoxin Res, 9 (3), 155-63
DOI 10.1179/096805103125001559, PubMed 12831456

Distante S, Elmberg M, Foss Haug KB, Ovstebø R, Berg JP, Kierulf P, Hultcrantz R, Bell H (2003)
Tumour necrosis factor alpha and its promoter polymorphisms' role in the phenotypic expression of hemochromatosis
Scand J Gastroenterol, 38 (8), 871-7
DOI 10.1080/00365520310003444, PubMed 12940442

Distante S, Elmberg M, Foss Haug KB, Øvstebø R, Berg JP, Kierulf P, Hultcrantz R, Bell H (2003)
Tumor necrosis factor alpha and its promoter polymorphisms' role in the phenotypic expression of hemachromatosis
In Scandinavian journal of gastroenterology, Taylor & Francis, Basingstoke, 38(2003)8, s.871-7
BIBSYS 041707850

Møller AS, Øvstebø R, Westvik AB, Joø GB, Haug KB, Kierulf P (2003)
Effects of bacterial cell wall components (PAMPs) on the expression of monocyte chemoattractant protein-1 (MCP-1), macrophage inflammatory protein-1alpha (MIP-1alpha) and the chemokine receptor CCR2 by purified human blood monocytes
J Endotoxin Res, 9 (6), 349-60
DOI 10.1179/096805103225002791, PubMed 14733721

Øvstebø R, Haug KB, Lande K, Kierulf P (2003)
PCR-based calibration curves for studies of quantitative gene expression in human monocytes: development and evaluation
Clin Chem, 49 (3), 425-32
DOI 10.1373/49.3.425, PubMed 12600954

Publications 2002

Lund PK, Namork E, Brorson SH, Westvik AB, Joø GB, Øvstebø R, Kierulf P (2002)
The fate of monocytes during 24 h of culture as revealed by flow cytometry and electron microscopy
J Immunol Methods, 270 (1), 63-76
DOI 10.1016/s0022-1759(02)00272-7, PubMed 12379339

Publications 2001

Brandtzaeg P, Bjerre A, Øvstebø R, Brusletto B, Joø GB, Kierulf P (2001)
Neisseria meningitidis lipopolysaccharides in human pathology
J Endotoxin Res, 7 (6), 401-20
DOI 10.1177/09680519010070060401, PubMed 11753210

Brandtzaeg P, Ovstebø R, Kierulf P (2001)
Quantitative detection of bacterial lipopolysaccharides in clinical specimens
Methods Mol Med, 67, 427-39
DOI 10.1385/1-59259-149-3:427, PubMed 21337159

Lund PK, Westvik AB, Joø GB, Øvstebø R, Haug KB, Kierulf P (2001)
Flow cytometric evaluation of apoptosis, necrosis and recovery when culturing monocytes
J Immunol Methods, 252 (1-2), 45-55
DOI 10.1016/s0022-1759(01)00330-1, PubMed 11334964

Møller AW, Haug KB, Øvstebø R, Joø GB, Westvik AB, Kierulf P (2001)
Non-mannose-capped lipoarabinomannan stimulates human peripheral monocytes to expression of the "early immediate genes" tissue factor and tumor necrosis factor-alpha
Thromb Res, 102 (3), 273-83
DOI 10.1016/s0049-3848(01)00248-1, PubMed 11369421

Publications 2000

Bjerre A, Brusletto B, Rosenqvist E, Namork E, Kierulf P, Øvstebø R, Joø GB, Brandtzaeg P (2000)
Cellular activating properties and morphology of membrane-bound and purified meningococcal lipopolysaccharide
J Endotoxin Res, 6 (6), 437-45
DOI 10.1179/096805100101532397, PubMed 11521068

Bjerre A, Ovstebø R, Kierulf P, Halvorsen S, Brandtzaeg P (2000)
Fulminant meningococcal septicemia: dissociation between plasma thrombopoietin levels and platelet counts
Clin Infect Dis, 30 (4), 643-7
DOI 10.1086/313754, PubMed 10770723

Lund PK, Joø GB, Westvik AB, Ovstebø R, Kierulf P (2000)
Isolation of monocytes from whole blood by density gradient centrifugation and counter-current elutriation followed by cryopreservation: six years' experience
Scand J Clin Lab Invest, 60 (5), 357-65
DOI 10.1080/003655100750019260, PubMed 11003255

Osnes LT, Haug KB, Joø GB, Westvik AB, Ovstebø R, Kierulf P (2000)
Aspirin potentiates LPS-induced fibrin formation (FPA) and TNF-alpha-synthesis in whole blood
Thromb Haemost, 83 (6), 868-73
PubMed 10896240

Publications 1998

Øvstebø R (1998)
Kvantitativ påvisning av tissue factor mRNA i humane monocytter ved bruk av RT-PCR
R. Øvstebø, [Trondheim], 107 bl.
BIBSYS 990519759

Publications 1996

Brandtzaeg P, Osnes L, Ovstebø R, Joø GB, Westvik AB, Kierulf P (1996)
Net inflammatory capacity of human septic shock plasma evaluated by a monocyte-based target cell assay: identification of interleukin-10 as a major functional deactivator of human monocytes
J Exp Med, 184 (1), 51-60
DOI 10.1084/jem.184.1.51, PubMed 8691149

Osnes LT, Foss KB, Joø GB, Okkenhaug C, Westvik AB, Ovstebø R, Kierulf P (1996)
Acetylsalicylic acid and sodium salicylate inhibit LPS-induced NF-kappa B/c-Rel nuclear translocation, and synthesis of tissue factor (TF) and tumor necrosis factor alfa (TNF-alpha) in human monocytes
Thromb Haemost, 76 (6), 970-6
PubMed 8972019

Publications 1995

Brandtzaeg P, Ovstebø R, Kierulf P (1995)
Bacteremia and compartmentalization of LPS in meningococcal disease
Prog Clin Biol Res, 392, 219-33
PubMed 8524927

Eggesbø JB, Hjermann I, Joø GB, Ovstebø R, Kierulf P (1995)
LPS-induced release of EGF, GM-CSF, GRO alpha, LIF, MIP-1 alpha and PDGF-AB in PBMC from persons with high or low levels of HDL lipoprotein
Cytokine, 7 (6), 562-7
DOI 10.1006/cyto.1995.0076, PubMed 8580373

Eggesbø JB, Hjermann I, Ovstebø R, Joø GB, Kierulf P (1995)
LPS induced procoagulant activity and plasminogen activator activity in mononuclear cells from persons with high or low levels of HDL lipoprotein
Thromb Res, 77 (5), 441-52
DOI 10.1016/0049-3848(95)93880-9, PubMed 7778059

Publications 1994

Eggesbø JB, Hjermann I, Lund PK, Joø GB, Ovstebø R, Kierulf P (1994)
LPS-induced release of IL-1 beta, IL-6, IL-8, TNF-alpha and sCD14 in whole blood and PBMC from persons with high or low levels of HDL-lipoprotein
Cytokine, 6 (5), 521-9
DOI 10.1016/1043-4666(94)90080-9, PubMed 7530060

Nordsletten L, Kaastad TS, Madsen JE, Reikerås O, Ovstebø R, Strømme JH, Falch J (1994)
The development of femoral osteopenia in ovariectomized rats is not reduced by high intensity treadmill training: a mechanical and densitometric study
Calcif Tissue Int, 55 (6), 436-42
DOI 10.1007/BF00298557, PubMed 7895182

Publications 1992

Brandtzaeg P, Bryn K, Kierulf P, Ovstebø R, Namork E, Aase B, Jantzen E (1992)
Meningococcal endotoxin in lethal septic shock plasma studied by gas chromatography, mass-spectrometry, ultracentrifugation, and electron microscopy
J Clin Invest, 89 (3), 816-23
DOI 10.1172/JCI115660, PubMed 1541674

Høgevold HE, Kierulf P, Ovstebø R, Reikerås O (1992)
Acute phase reactants and interleukin 6 after total hip replacement. Effects of high dose corticosteroids
Eur J Surg, 158 (6-7), 339-45
PubMed 1382623

Osnes T, Kierulf P, Skar V, Skar AG, Ovstebø R, Osnes M (1992)
Quantification of lipopolysaccharides in human bile with or without gram-negative bacteria
Scand J Gastroenterol, 27 (6), 453-8
DOI 10.3109/00365529209000105, PubMed 1631492

Publications 1989

Brandtzaeg P, Sandset PM, Joø GB, Ovstebø R, Abildgaard U, Kierulf P (1989)
The quantitative association of plasma endotoxin, antithrombin, protein C, extrinsic pathway inhibitor and fibrinopeptide A in systemic meningococcal disease
Thromb Res, 55 (4), 459-70
DOI 10.1016/0049-3848(89)90054-6, PubMed 2510354

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