Publications 2024

Aune A, Ohldieck A, Halvorsen LV, Brobak KM, Olsen E, Rognstad S, Larstorp ACK, Søraas CL, Rossebø AB, Rösner A, Grytaas MA, Gerdts E (2024)
Gender Differences in Cardiac Organ Damage in Arterial Hypertension: Assessing the Role of Drug Nonadherence
High Blood Press Cardiovasc Prev, 31 (2), 157-166
DOI 10.1007/s40292-024-00632-6, PubMed 38530572

Brobak KM, Halvorsen LV, Aass HCD, Søraas CL, Aune A, Olsen E, Bergland OU, Rognstad S, Blom KB, Birkeland JAK, Høieggen A, Larstorp ACK, Solbu MD (2024)
Novel biomarkers in patients with uncontrolled hypertension with and without kidney damage
Blood Press, 33 (1), 2323980
DOI 10.1080/08037051.2024.2323980, PubMed 38606688

Halvorsen LV, Søraas CL, Larstorp ACK, Hjørnholm U, Kjær VN, Liestøl K, Aune A, Olsen E, Brobak KM, Bergland OU, Rognstad S, Aarskog NR, Heimark S, Fadl Elmula FEM, Gerdts E, Mo R, Solbu MD, Opdal MS, Kjeldsen SE, Rostrup M, Høieggen A (2024)
Effect of Therapeutic Drug Monitoring on Adherence and Blood Pressure: A Multicenter Randomized Clinical Trial
Am J Hypertens, 37 (10), 826-836
DOI 10.1093/ajh/hpae059, PubMed 38713475

Hove C, Sæter FW, Stepanov A, Bøtker-Rasmussen KG, Seeberg TM, Westgaard E, Heimark S, Waldum-Grevbo B, Hisdal J, Larstorp ACK (2024)
A prototype photoplethysmography-based cuffless device shows promising results in tracking changes in blood pressure
Front Med Technol, 6, 1464473
DOI 10.3389/fmedt.2024.1464473, PubMed 39498215

Olsen E, Jamerson K, Schmieder RE, Søraas CL, Mariampillai JE, Mancia G, Kjeldsen SE, Heimark S, Mehlum MH, Liestøl K, Larstorp ACK, Halvorsen LV, Høieggen A, Burnier M, Rostrup M, Julius S, Weber MA (2024)
Effects of valsartan vs amlodipine and achieved lower blood pressure on the incidence of end-stage kidney disease: The VALUE Trial
Eur J Intern Med (in press)
DOI 10.1016/j.ejim.2024.12.021, PubMed 39694747

Opdal MS, Rognstad S, Edvardsen F, Halvorsen LV, Mo R, Gustavsen I, Larstorp ACK, Søraas CL, Helland A (2024)
[Not Available]
Tidsskr Nor Laegeforen, 144
DOI 10.4045/tidsskr.24.0407, PubMed 39149754

Opdal MS, Rognstad S, Edvardsen F, Halvorsen LV, Mo R, Gustavsen I, Larstorp ACK, Søraas CL, Helland A (2024)
Usefulness of measuring the serum concentration of antihypertensive drugs in uncontrolled hypertension
Tidsskr Nor Laegeforen, 144 (9)
DOI 10.4045/tidsskr.24.0167, PubMed 39167005

Publications 2023

Heimark S, Hove C, Stepanov A, Boysen ES, Gløersen Ø, Bøtke-Rasmussen KG, Gravdal HJ, Narayanapillai K, Fadl Elmula FEM, Seeberg TM, Larstorp ACK, Waldum-Grevbo B (2023)
Accuracy and User Acceptability of 24-hour Ambulatory Blood Pressure Monitoring by a Prototype Cuffless Multi-Sensor Device Compared to a Conventional Oscillometric Device
Blood Press, 32 (1), 2274595
DOI 10.1080/08037051.2023.2274595, PubMed 37885101

Heimark S, Mehlum MH, Mancia G, Søraas CL, Liestøl K, Wachtell K, Larstorp AC, Rostrup M, Mariampillai JE, Kjeldsen SE, Julius S, Weber MA (2023)
Middle-Aged and Older Patients With Left Ventricular Hypertrophy: Higher Mortality With Drug Treated Systolic Blood Pressure Below 130 mm Hg
Hypertension, 80 (8), 1739-1748
DOI 10.1161/HYPERTENSIONAHA.123.21454, PubMed 37350267

Mariampillai JE, Halvorsen LV, Larstorp AC, Heimark S, Waldum-Grevbo B, Kjeldsen SE, Nordby G, Stenehjem AE, Berg JP, Høieggen A (2023)
[Diabetes and chronic kidney disease]
Tidsskr Nor Laegeforen, 143 (12)
DOI 10.4045/tidsskr.22.0822, PubMed 37668137

Publications 2022

Fjeld B, Sudmann-Day ÅA, Grimholt RM, Larstorp ACK, Urdal P, Klingenberg O (2022)
Additional value of red blood cell parameters in predicting uncommon α-thalassemia; experience from 10 years of α-globin gene sequencing and copy number variation analysis
Int J Lab Hematol, 45 (2), 250-259
DOI 10.1111/ijlh.14010, PubMed 36567661

Halvorsen LV, Bergland OU, Søraas CL, Larstorp ACK, Hjørnholm U, Kjær VN, Kringen MK, Clasen PE, Haldsrud R, Kjeldsen SE, Rostrup M, Fadl Elmula FEM, Opdal MS, Høieggen A (2022)
Nonadherence by Serum Drug Analyses in Resistant Hypertension: 7-Year Follow-Up of Patients Considered Adherent by Directly Observed Therapy
J Am Heart Assoc, 11 (18), e025879
DOI 10.1161/JAHA.121.025879, PubMed 36073648

Larstorp ACK, Salvador CL, Svensvik BA, Klingenberg O, Distante S (2022)
Neutrophil Gelatinase-Associated Lipocalin (NGAL) and cystatin C are early biomarkers of acute kidney injury associated with cardiac surgery
Scand J Clin Lab Invest, 82 (5), 410-418
DOI 10.1080/00365513.2022.2114105, PubMed 36036280

Lilja-Cyron A, Bang CN, Gerdts E, Larstorp AC, Kjeldsen SE, Julius S, Okin PM, Wachtell K, Devereux RB (2022)
Aortic Root Dilatation in Hypertensive Patients with Left Ventricular Hypertrophy-Application of A New Multivariate Predictive Model. The Life Study
Rev Cardiovasc Med, 23 (3), 95
DOI 10.31083/j.rcm2303095, PubMed 35345262

Thorstensen CW, Clasen PE, Rognstad S, Haldsrud R, Føreid S, Helstrøm T, Bergland OU, Halvorsen LV, Aune A, Olsen E, Brobak KM, Høieggen A, Gustavsen I, Larstorp ACK, Søraas CL, Opdal MS (2022)
Development of UHPLC-MS/MS methods to quantify 25 antihypertensive drugs in serum in a cohort of patients treated for hypertension
J Pharm Biomed Anal, 219, 114908
DOI 10.1016/j.jpba.2022.114908, PubMed 35803015

Publications 2021

Bergland OU, Halvorsen LV, Søraas CL, Hjørnholm U, Kjær VN, Rognstad S, Brobak KM, Aune A, Olsen E, Fauchald YM, Heimark S, Thorstensen CW, Liestøl K, Solbu MD, Gerdts E, Mo R, Rostrup M, Kjeldsen SE, Høieggen A, Opdal MS, Larstorp ACK, Fadl Elmula FEM (2021)
Detection of Nonadherence to Antihypertensive Treatment by Measurements of Serum Drug Concentrations
Hypertension, 78 (3), 617-628
DOI 10.1161/HYPERTENSIONAHA.121.17514, PubMed 34275336

Johannessen TR, Atar D, Vallersnes OM, Larstorp ACK, Mdala I, Halvorsen S (2021)
Comparison of a single high-sensitivity cardiac troponin T measurement with the HEART score for rapid rule-out of acute myocardial infarction in a primary care emergency setting: a cohort study
BMJ Open, 11 (2), e046024
DOI 10.1136/bmjopen-2020-046024, PubMed 33627355

Olsen E, Holzhauer B, Julius S, Kjeldsen SE, Larstorp ACK, Mancia G, Mehlum MH, Mo R, Rostrup M, Søraas CL, Zappe D, Weber MA (2021)
Cardiovascular outcomes at recommended blood pressure targets in middle-aged and elderly patients with type 2 diabetes mellitus and hypertension
Blood Press, 30 (2), 82-89
DOI 10.1080/08037051.2020.1855968, PubMed 33403886

Olsen E, Holzhauer B, Julius S, Kjeldsen SE, Larstorp ACK, Mancia G, Mehlum MH, Mo R, Rostrup M, Søraas CL, Zappe D, Weber MA (2021)
Cardiovascular outcomes at recommended blood pressure targets in middle-aged and elderly patients with type 2 diabetes mellitus compared to all middle-aged and elderly hypertensive study patients with high cardiovascular risk
Blood Press, 30 (2), 90-97
DOI 10.1080/08037051.2020.1856642, PubMed 33403890

Undrum Bergland O, Larstorp ACK, Lund Søraas C, Høieggen A, Rostrup M, Norheim Kjaer V, Godang K, Sevre K, Fadl Elmula FEM (2021)
Changes in sympathetic nervous system activity after renal denervation: results from the randomised Oslo RDN study
Blood Press, 30 (3), 154-164
DOI 10.1080/08037051.2020.1868286, PubMed 33399016

Publications 2020

Bergland OU, Søraas CL, Larstorp ACK, Halvorsen LV, Hjørnholm U, Hoffman P, Høieggen A, Fadl Elmula FEM (2020)
The randomised Oslo study of renal denervation vs. Antihypertensive drug adjustments: efficacy and safety through 7 years of follow-up
Blood Press, 30 (1), 41-50
DOI 10.1080/08037051.2020.1828818, PubMed 33030064

Bergo KK, Larstorp AC, Hoffmann P, Hjørnholm U, Cataliotti A, Høieggen A, Rostrup M, Fadl Elmula FEM (2020)
Renal sympathetic denervation lowers systemic vascular resistance in true treatment-resistant hypertension
Blood Press, 30 (1), 31-40
DOI 10.1080/08037051.2020.1789446, PubMed 32633141

Johannessen TR, Vallersnes OM, Halvorsen S, Larstorp ACK, Mdala I, Atar D (2020)
Pre-hospital One-Hour Troponin in a Low-Prevalence Population of Acute Coronary Syndrome: OUT-ACS study
Open Heart, 7 (2)
DOI 10.1136/openhrt-2020-001296, PubMed 32719074

Publications 2019

Hjørnholm U, Larstorp ACK, Andersen MH, Høieggen A (2019)
Directly observed therapy prior to ambulatory blood pressure measurement (DOT-HTN) in uncontrolled hypertensive patients - Effect on blood pressure, safety and patient perception
Blood Press, 28 (5), 327-335
DOI 10.1080/08037051.2019.1633907, PubMed 31250668

Larstorp ACK, Stokke IM, Kjeldsen SE, Hecht Olsen M, Okin PM, Devereux RB, Wachtell K (2019)
Antihypertensive therapy prevents new-onset atrial fibrillation in patients with isolated systolic hypertension: the LIFE study
Blood Press, 28 (5), 317-326
DOI 10.1080/08037051.2019.1633905, PubMed 31259628

Skaaland H, Larstorp ACK, Lindberg M, Jacobsen D (2019)
Reference values for osmolal gap in healthy subjects and in medical inpatients
Scand J Clin Lab Invest, 80 (1), 1-5
DOI 10.1080/00365513.2019.1672086, PubMed 31809199

Publications 2018

Talvik A, Rebora P, Heinpalu-Kuum M, Salerno S, Miszkowska-Nagórna E, Liu X, Comotti T, Świerblewska E, Valsecchi MG, Fadl Elmula FEM, Larstorp AC, Narkiewicz K, Parati G, Laurent S, Viigimaa M, BEtter control of blood pressure in hypertensive pAtients monitored Using the hoTman® sYstem (BEAUTY) Study Investigators (2018)
Non-invasive hemodynamic monitoring as a guide to drug treatment of uncontrolled hypertensive patients: effects on home blood pressure in the BEAUTY study
Blood Press, 27 (6), 368-375
DOI 10.1080/08037051.2018.1505425, PubMed 30129785

Tjora S, Hall TS, Larstorp AC, Hallen J, Atar D (2018)
Increases in Circulating Cardiac Troponin Are Not Always Associated with Myocardial Cell Death
Clin Lab, 64 (11)
DOI 10.7754/Clin.Lab.2018.180615, PubMed 30549980

Publications 2017

Fadl Elmula FEM, Feng YM, Jacobs L, Larstorp AC, Kjeldsen SE, Persu A, Staessen JA, European Network COordinating research on Renal Denervation (ENCOReD) (2017)
Sham or no sham control: that is the question in trials of renal denervation for resistant hypertension. A systematic meta-analysis
Blood Press, 26 (4), 195-203
DOI 10.1080/08037051.2017.1311769, PubMed 28443356

Mariampillai JE, Eskås PA, Heimark S, Larstorp AC, Fadl Elmula FE, Høieggen A, Nortvedt P (2017)
Apparent treatment-resistant hypertension - patient-physician relationship and ethical issues
Blood Press, 26 (3), 133-138
DOI 10.1080/08037051.2016.1277129, PubMed 28078909

Publications 2016

Eskas PA, Heimark S, Mariampillai JE, Larstorp ACK, Elmula FEMF, Hoieggen A (2016)
Drug compliance and monitoring of antihypertensive treatment
Tidsskr. Nor. Laegeforen., 136 (10), 920-923

Eskås PA, Heimark S, Eek Mariampillai J, Larstorp AC, Fadl Elmula FE, Høieggen A (2016)
Adherence to medication and drug monitoring in apparent treatment-resistant hypertension
Blood Press, 25 (4), 199-205
DOI 10.3109/08037051.2015.1121706, PubMed 26729283

Eskås PA, Heimark S, Mariampillai JE, Larstorp AC, Fadl Elmula FE, Høieggen A (2016)
[Medication adherence and monitoring of antihypertensive treatment]
Tidsskr Nor Laegeforen, 136 (10), 920-3
DOI 10.4045/tidsskr.15.0978, PubMed 27272370

Heimark S, Eskås PA, Mariampillai JE, Larstorp AC, Høieggen A, Fadl Elmula FE (2016)
Tertiary work-up of apparent treatment-resistant hypertension
Blood Press, 25 (5), 312-8
DOI 10.3109/08037051.2016.1172865, PubMed 27124769

Larstorp AC, Tonstad S (2016)
Effect of a Low Fat Diet Intervention on Blood Pressure and Hypertension: Rather Switch to a Mediterranean Diet?
Am J Hypertens, 29 (8), 900-3
DOI 10.1093/ajh/hpw054, PubMed 27245068

Publications 2015

Fadl Elmula FE, Jin Y, Yang WY, Thijs L, Lu YC, Larstorp AC, Persu A, Sapoval M, Rosa J, Widimský P, Jacobs L, Renkin J, Petrák O, Chatellier G, Shimada K, Widimský J, Kario K, Azizi M, Kjeldsen SE, Staessen JA, European Network Coordinating Research On Renal Denervation (ENCOReD) Consortium (2015)
Meta-analysis of randomized controlled trials of renal denervation in treatment-resistant hypertension
Blood Press, 24 (5), 263-74
DOI 10.3109/08037051.2015.1058595, PubMed 26194721

Fadl Elmula FE, Larstorp AC, Kjeldsen SE, Persu A, Jin Y, Staessen JA (2015)
Renal sympathetic denervation after Symplicity HTN-3 and therapeutic drug monitoring in severe hypertension
Front Physiol, 6, 9
DOI 10.3389/fphys.2015.00009, PubMed 25709581

Fadl Elmula FE, Rebora P, Talvik A, Salerno S, Miszkowska-Nagórna E, Liu X, Heinpalu-Kuum M, Comotti T, Larstorp AC, Rostrup M, Świerblewska E, Valsecchi MG, Kjeldsen SE, Viigimaa M, Narkiewicz K, Parati G, Laurent S, BEtter control of blood pressure in hypertensive pAtients monitored Using the HOTMAN sYstem (BEAUTY) Study Investigators (2015)
A randomized and controlled study of noninvasive hemodynamic monitoring as a guide to drug treatment of uncontrolled hypertensive patients
J Hypertens, 33 (12), 2534-45
DOI 10.1097/HJH.0000000000000749, PubMed 26485460

Okin PM, Hille DA, Larstorp AC, Wachtell K, Kjeldsen SE, Dahlöf B, Devereux RB (2015)
Effect of lower on-treatment systolic blood pressure on the risk of atrial fibrillation in hypertensive patients
Hypertension, 66 (2), 368-73
DOI 10.1161/HYPERTENSIONAHA.115.05728, PubMed 26056336

Publications 2014

Fadl Elmula FE, Hoffmann P, Larstorp AC, Fossum E, Brekke M, Kjeldsen SE, Gjønnæss E, Hjørnholm U, Kjaer VN, Rostrup M, Os I, Stenehjem A, Høieggen A (2014)
Adjusted drug treatment is superior to renal sympathetic denervation in patients with true treatment-resistant hypertension
Hypertension, 63 (5), 991-9
DOI 10.1161/HYPERTENSIONAHA.114.03246, PubMed 24591332

Publications 2012

Larstorp AC, Ariansen I, Gjesdal K, Olsen MH, Ibsen H, Devereux RB, Okin PM, Dahlöf B, Kjeldsen SE, Wachtell K (2012)
Association of pulse pressure with new-onset atrial fibrillation in patients with hypertension and left ventricular hypertrophy: the Losartan Intervention For Endpoint (LIFE) reduction in hypertension study
Hypertension, 60 (2), 347-53
DOI 10.1161/HYPERTENSIONAHA.112.195032, PubMed 22753219

Larstorp AC, Okin PM, Devereux RB, Olsen MH, Ibsen H, Dahlöf B, Kjeldsen SE, Wachtell K (2012)
Regression of ECG-LVH is associated with lower risk of new-onset heart failure and mortality in patients with isolated systolic hypertension; The LIFE study
Am J Hypertens, 25 (10), 1101-9
DOI 10.1038/ajh.2012.86, PubMed 22717544

Publications 2011

Søraas CL, Larstorp AC, Mangschau A, Tønnessen T, Kjeldsen SE, Bjørnerheim R (2011)
Echocardiographic demonstration of improved myocardial function early after coronary artery bypass graft surgery
Interact Cardiovasc Thorac Surg, 12 (6), 946-51
DOI 10.1510/icvts.2010.260414, PubMed 21422155

Publications 2010

Larstorp AC, Okin PM, Devereux RB, Olsen MH, Ibsen H, Dahlöf B, Kjeldsen SE, Wachtell K (2010)
Changes in electrocardiographic left ventricular hypertrophy and risk of major cardiovascular events in isolated systolic hypertension: the LIFE study
J Hum Hypertens, 25 (3), 178-85
DOI 10.1038/jhh.2010.52, PubMed 20505749

Wiik BP, Larstorp AC, Høieggen A, Kjeldsen SE, Olsen MH, Ibsen H, Lindholm L, Dahlöf B, Devereux RB, Okin PM, Wachtell K (2010)
Serum uric acid is associated with new-onset diabetes in hypertensive patients with left ventricular hypertrophy: The LIFE Study
Am J Hypertens, 23 (8), 845-51
DOI 10.1038/ajh.2010.89, PubMed 20431530

Publications 2006

Larstorp AC, Lund Søraas C, Tønnessen T, Müller C, Kjeldsen SE, Mangschau A (2006)
Scintigraphic demonstration of myocardial perfusion and ischaemia associated with coronary artery bypass grafting
Scand Cardiovasc J, 40 (6), 354-62
DOI 10.1080/14017430601004063, PubMed 17118826