Karina Hougen
- Consultant; MD, PhD
Publications 2021
Exercise Training Stabilizes RyR2-Dependent Ca2+ Release in Post-infarction Heart Failure
Front. Cardiovasc. Med., 7, 623922
DOI 10.3389/fcvm.2020.623922
Publications 2020
Coupling of the Na+/K+-ATPase to Ankyrin B controls Na+/Ca2+ exchanger activity in cardiomyocytes
Cardiovasc. Res., 116 (1), 78-90
DOI 10.1093/cvr/cvz087
Publications 2017
PDE3 inhibition by C-type natriuretic peptide-induced cGMP enhances cAMP-mediated signaling in both non-failing and failing hearts
Eur. J. Pharmacol., 812, 174-183
DOI 10.1016/j.ejphar.2017.07.014
Publications 2016
Beta-Adrenoceptor Stimulation Reveals Ca2+ Waves and Sarcoplasmic Reticulum Ca2+ Depletion in Left Ventricular Cardiomyocytes from Post-Infarction Rats with and without Heart Failure
PLoS One, 11 (4), e0153887
DOI 10.1371/journal.pone.0153887
Publications 2013
Slow Ca2+ sparks de-synchronize Ca2+ release in failing cardiomyocytes: Evidence for altered configuration of Ca2+ release units?
J. Mol. Cell. Cardiol., 58, 41-52
DOI 10.1016/j.yjmcc.2013.01.014
I-CaL inhibition prevents arrhythmogenic Ca2+ waves caused by abnormal Ca2+ sensitivity of RyR or SR Ca2+ accumulation
Cardiovasc. Res., 98 (2), 315-325
DOI 10.1093/cvr/cvt037
Publications 2010
Cre-loxP DNA recombination is possible with only minimal unspecific transcriptional changes and without cardiomyopathy in Tg(alpha MHC-MerCreMer) mice
Am. J. Physiol.-Heart Circul. Physiol., 299 (5), H1671-H1678
DOI 10.1152/ajpheart.01155.2009
Sodium accumulation promotes diastolic dysfunction in end-stage heart failure following Serca2 knockout
J. Physiol.-London, 588 (3), 465-478
DOI 10.1113/jphysiol.2009.183517
Natriuretic peptides increase beta(1)-adrenoceptor signalling in failing hearts through phosphodiesterase 3 inhibition
Cardiovasc. Res., 85 (4), 763-772
DOI 10.1093/cvr/cvp364
Reduced SERCA2 abundance decreases the propensity for Ca2+ wave development in ventricular myocytes
Cardiovasc. Res., 86 (1), 63-71
DOI 10.1093/cvr/cvp401