Cardiac Intensive Care Research Unit (CICRU)

Group leader:Geir Ø. Andersen
Group leader:
Geir Ø. Andersen

Main aim: 

Clinical heart research with translational aspects focusing on patients with acute ST-elevation myocardial infarction (STEMI) or cardiac arrest admitted to the cardiac intensive care unit (CICU). 

Primary objectives: 

  1. To explore in detail the pathogenesis of acute coronary syndromes ((ACS) including STEMI) and ischemia-reperfusion injury with focus on how systemic and local inflammation may potentially contribute to plaque destabilization and myocardial damage.
  2. Interventional studies targeting ischemia/reperfusion injury aiming to reduce infarct size
  3. Treatment of acute heart failure and cardiogenic shock complicating STEMI
  4. Prognostication, monitoring and treatment of patients with out-of- hospital cardiac arrest in order to improve survival and neurological prognosis
  5. Obtain new mechanistic insights on the importance of residual inflammation on patients with ACS, open the way for novel treatment and prevention options