We work on uncovering and understanding novel mechanisms of autophagy termination. Our main model organism is Drosophila, which is a strong tool to address questions of autophagy regulation in context of the entire organism. 

Our main goals are to

• Understand how autophagy termination is regulated and how this affects the development and fitness of the organism, as well as the interconnection with physiological processes such as sleep.
• Understand nutrient signaling pathways such as autophagy in various forms of renal cancer with the aim of identifying biomarkers and developing novel forms of treatment.

Projects:

• Final act of the autophagy symphony: whole-organism orchestration of autophagy termination
• Unraveling the role of autophagy in kidney cancer
• Development of a platform for personalized treatment decisions for Renal Cell Carcinoma

Link to UiO home page (med.uio.no)

 

Contact information

Group leader Helene Knævelsrud, helene.knavelsrud@medisin.uio.no +47 414 27 591