Family-based Genetic Analysis
Our goal is to develop methods and software for family-based analysis in medical and forensic genetics.
Research projects
- Segregation analysis for evaluating variant pathogenicity. Part of the NRC-funded project Automation of clinical genetic variant interpretation
- The ped suite: A collection of R packages for pedigree analysis
- QuickPed: An online tool for interactive pedigree creation and analysis of relatedness
- Filtus: a desktop GUI for fast and efficient detection of disease-causing variants
- Analysis of exomes and genomes from related patients (various inhouse collaborators)
- The missing grandchildren in Argentina (with M. Herrera Piñero & colleagues at BNDG, Argentina)
- Disaster-victim identification (with T. Egeland, NMBU)
- Theoretical pedigree analysis
Book:
Pedigree analysis in R (Academic Press, 2021).
The book gives an introduction to the theory of relatedness and covers a variety of applications in forensic and medical genetics.
Contact information:
Magnus Dehli Vigeland: magnusdv@medisin.uio.no
Visiting /postal address: Dept. Medical Genetics, Building 25, 1st floor (North), Ullevål Hospital, Kirkeveien 166, 0450 Oslo