The Unit of Regenerative Medicine

The main goals of our research group are:

1) To develop storage and transport technologies for cultured stem cells from various origins (e.g., oral mucosal stem cells, Figure 1). We anticipate that this technology will be increasingly in demand as research in regenerative medicine becomes more widespread.

Figure 1. Possible steps in the treatment of limbal stem cell deficiency (Utheim et al., 2016).

 

2) Treating eye diseases affecting both the front and back of the eye is also an important part of our work, particularly addressing limbal stem cell deficiency using alternative cell types, such as cultured epidermal and oral mucosal stem cells (Figure 2). Our research primarily focuses on stem cells in the areas of the eye and skin.

Figure 2. Culture of human oral mucosal epithelial cells on hyaluronan hydrogel scaffold coated with collagen (right) compared to control (left) (Yazdani et al., 2019).

 

3) Another focus of our research is improving the diagnosis and treatment of patients with dry eye disease, based on analyses of clinical data.

Figure 3. Stages of dry eye disease (Yazdani et al., 2019).

 

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