Publications
Publications published since 2000 from OUS - Department of Radiation Biology
948 publications found
Publications 2024
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Discovery and technical validation of high-performance methylated DNA markers for the detection of cervical lesions at risk of malignant progression in low- and middle-income countries
Clin Epigenetics, 16 (1), 56
DOI 10.1186/s13148-024-01669-z, PubMed 38643219 -
A DWI-based hypoxia model shows robustness in an external prostatectomy cohort
Front Oncol, 14, 1433197
DOI 10.3389/fonc.2024.1433197, PubMed 39109282 -
ALDH1A1 drives prostate cancer metastases and radioresistance by interplay with AR- and RAR-dependent transcription
Theranostics, 14 (2), 714-737
DOI 10.7150/thno.88057, PubMed 38169509 -
Immunophenotyping with (phospho)protein profiling and fluorescent cell barcoding for single-cell signaling analysis and biomarker discovery
NPJ Precis Oncol, 8 (1), 107
DOI 10.1038/s41698-024-00604-y, PubMed 38769096 -
Chronic fatigue in long-term survivors of head and neck cancer treated with radiotherapy
Radiother Oncol, 195, 110231
DOI 10.1016/j.radonc.2024.110231, PubMed 38518958 -
Proton- compared to X-irradiation leads to more acinar atrophy and greater hyposalivation accompanied by a differential cytokine response
Sci Rep, 14 (1), 22311
DOI 10.1038/s41598-024-73110-7, PubMed 39333378 -
Antigen targeting and anti-tumor activity of a novel anti-CD146 212Pb internalizing alpha-radioimmunoconjugate against malignant peritoneal mesothelioma
Sci Rep, 14 (1), 25941
DOI 10.1038/s41598-024-76778-z, PubMed 39472474 -
Corrigendum: Light-enhanced VEGF121/rGel induce immunogenic cell death and increase the antitumor activity of αCTLA4 treatment
Front Immunol, 14, 1359973
DOI 10.3389/fimmu.2023.1359973, PubMed 38264651 -
An Immune Gene Expression Risk Score for Distant Metastases after Radiotherapy for Cervical Cancer
Clin Cancer Res, 30 (6), 1200-1207
DOI 10.1158/1078-0432.CCR-23-2085, PubMed 38180733 -
A T2-weighted MRI-based radiomic signature for disease-free survival in locally advanced cervical cancer following chemoradiation: An international, multicentre study
Radiother Oncol, 199, 110463
DOI 10.1016/j.radonc.2024.110463, PubMed 39067707 -
Combination of proton- or X-irradiation with anti-PDL1 immunotherapy in two murine oral cancers
Sci Rep, 14 (1), 11569
DOI 10.1038/s41598-024-62272-z, PubMed 38773258 -
Author Correction: Combination of proton- or X-irradiation with anti-PDL1 immunotherapy in two murine oral cancers
Sci Rep, 14 (1), 15311
DOI 10.1038/s41598-024-66148-0, PubMed 38961180 -
Potential Benefits of Combining Proton or Carbon Ion Therapy with DNA Damage Repair Inhibitors
Cells, 13 (12)
DOI 10.3390/cells13121058, PubMed 38920686 -
Topical collection on photodynamic therapy-enhanced antitumour immunity
Photochem Photobiol Sci, 23 (2), 213-214
DOI 10.1007/s43630-024-00549-y, PubMed 38381362 -
Exploring the Impact of mRNA Modifications on Translation Efficiency and Immune Tolerance to Self-Antigens
Vaccines (Basel), 12 (6)
DOI 10.3390/vaccines12060624, PubMed 38932353 -
Spatial analysis of microRNA regulation at defined tumor hypoxia levels reveals biological traits of aggressive prostate cancer
J Pathol, 264 (3), 270-283
DOI 10.1002/path.6344, PubMed 39329425 -
MRI-guided dynamic risk assessment in cervical cancer based on tumor hypoxia at diagnosis and volume response at brachytherapy
Radiother Oncol, 195, 110263
DOI 10.1016/j.radonc.2024.110263, PubMed 38556173 -
Outcome prediction based on [18F]FDG PET/CT in patients with pleural mesothelioma treated with ipilimumab and nivolumab +/- UV1 telomerase vaccine
Eur J Nucl Med Mol Imaging (in press)
DOI 10.1007/s00259-024-06853-0, PubMed 39133306
Publications 2023
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Stability of metabolic tumor volume may enable radiotherapy dose painting in anal cancer
Phys Med, 114, 103151
DOI 10.1016/j.ejmp.2023.103151, PubMed 37813051 -
Analysis of RNA Polymerase II Chromatin Binding by Flow Cytometry
Bio Protoc, 13 (8), e4659
DOI 10.21769/BioProtoc.4659, PubMed 37113330 -
Editorial: Targeted alpha particle therapy in oncology
Front Med (Lausanne), 10, 1165747
DOI 10.3389/fmed.2023.1165747, PubMed 36960341 -
Macrophages as a photosensitizer delivery system for photodynamic therapy: Potential for the local treatment of resected glioblastoma
Photodiagnosis Photodyn Ther, 45, 103897
DOI 10.1016/j.pdpdt.2023.103897, PubMed 37984525 -
Immunogenic cell death after combined treatment with radiation and ATR inhibitors is dually regulated by apoptotic caspases
Front Immunol, 14, 1138920
DOI 10.3389/fimmu.2023.1138920, PubMed 37346039 -
Use of antihypertensive drugs and risk of cutaneous melanoma: a nationwide nested case-control study
Int J Epidemiol, 52 (3), 887-898
DOI 10.1093/ije/dyac223, PubMed 36413027 -
Proton Compared to X-Irradiation Induces Different Protein Profiles in Oral Cancer Cells and Their Derived Extracellular Vesicles
Int J Mol Sci, 24 (23)
DOI 10.3390/ijms242316983, PubMed 38069306 -
Dual targeting with 224Ra/212Pb-conjugates for targeted alpha therapy of disseminated cancers: A conceptual approach
Front Med (Lausanne), 9, 1051825
DOI 10.3389/fmed.2022.1051825, PubMed 36733936 -
Imaging of 212Pb in mice with a clinical SPECT/CT
EJNMMI Phys, 10 (1), 47
DOI 10.1186/s40658-023-00571-6, PubMed 37603123 -
Exploring Hypoxia in Prostate Cancer With T2-weighted Magnetic Resonance Imaging Radiomics and Pimonidazole Scoring
Anticancer Res, 43 (1), 351-357
DOI 10.21873/anticanres.16170, PubMed 36585179 -
Light-enhanced VEGF121/rGel induce immunogenic cell death and increase the antitumor activity of αCTLA4 treatment
Front Immunol, 14, 1278000
DOI 10.3389/fimmu.2023.1278000, PubMed 38173721 -
Upscale Synthesis of Magnetic Mesoporous Silica Nanoparticles and Application to Metal Ion Separation: Nanosafety Evaluation
Nanomaterials (Basel), 13 (24)
DOI 10.3390/nano13243155, PubMed 38133052 -
ALPL-1 is a target for chimeric antigen receptor therapy in osteosarcoma
Nat Commun, 14 (1), 3375
DOI 10.1038/s41467-023-39097-x, PubMed 37291203 -
MRI Assessment of Changes in Tumor Vascularization during Neoadjuvant Anti-Angiogenic Treatment in Locally Advanced Breast Cancer Patients
Cancers (Basel), 15 (18)
DOI 10.3390/cancers15184662, PubMed 37760629 -
CCDC66 regulates primary cilium length and signaling via interactions with transition zone and axonemal proteins
J Cell Sci, 136 (3)
DOI 10.1242/jcs.260327, PubMed 36606424 -
Small anticancer drug release by light: Photochemical internalization of porphyrin-β-cyclodextrin nanoparticles
Carbohydr Polym, 306, 120579
DOI 10.1016/j.carbpol.2023.120579, PubMed 36746578 -
Prostate cancer radiogenomics reveals proliferative gene expression programs associated with distinct MRI-based hypoxia levels
Radiother Oncol, 188, 109875
DOI 10.1016/j.radonc.2023.109875, PubMed 37640161 -
The GCN2/eIF2αK stress kinase regulates PP1 to ensure mitotic fidelity
EMBO Rep, 24 (8), e56100
DOI 10.15252/embr.202256100, PubMed 37291955 -
CSPP1 stabilizes growing microtubule ends and damaged lattices from the luminal side
J Cell Biol, 222 (4)
DOI 10.1083/jcb.202208062, PubMed 36752787 -
Cytokine Levels in Saliva Are Associated with Salivary Gland Fibrosis and Hyposalivation in Mice after Fractionated Radiotherapy of the Head and Neck
Int J Mol Sci, 24 (20)
DOI 10.3390/ijms242015218, PubMed 37894899
Publications 2022
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Myeloperoxidase exerts anti-tumor activity in glioma after radiotherapy
Neoplasia, 26, 100779
DOI 10.1016/j.neo.2022.100779, PubMed 35247801 -
A novel, rapid and sensitive flow cytometry method reveals degradation of promoter proximal paused RNAPII in the presence and absence of UV
Nucleic Acids Res, 50 (15), e89
DOI 10.1093/nar/gkac434, PubMed 35641102 -
Integrated analysis of cervical squamous cell carcinoma cohorts from three continents reveals conserved subtypes of prognostic significance
Nat Commun, 13 (1), 5818
DOI 10.1038/s41467-022-33544-x, PubMed 36207323 -
Caspase activation counteracts interferon signaling after G2 checkpoint abrogation by ATR inhibition in irradiated human cancer cells
Front Oncol, 12, 981332
DOI 10.3389/fonc.2022.981332, PubMed 36387237 -
3D-Structured Illumination Microscopy of Centrosomes in Human Cell Lines
Bio Protoc, 12 (6), e4360
DOI 10.21769/BioProtoc.4360, PubMed 35434191 -
5-ALA Is a Potent Lactate Dehydrogenase Inhibitor but Not a Substrate: Implications for Cell Glycolysis and New Avenues in 5-ALA-Mediated Anticancer Action
Cancers (Basel), 14 (16)
DOI 10.3390/cancers14164003, PubMed 36010996 -
An Experimental Generator for Production of High-Purity 212Pb for Use in Radiopharmaceuticals
J Nucl Med, 64 (1), 173-176
DOI 10.2967/jnumed.122.264009, PubMed 35798556 -
Targeted Therapy on the Screen: Do We Hit the Target?
Clin Cancer Res, 28 (24), 5233-5234
DOI 10.1158/1078-0432.CCR-22-2707, PubMed 36240006 -
Anti-CD37 radioimmunotherapy with 177Lu-NNV003 synergizes with the PARP inhibitor olaparib in treatment of non-Hodgkin's lymphoma in vitro
PLoS One, 17 (4), e0267543
DOI 10.1371/journal.pone.0267543, PubMed 35486574 -
Quantification of Tumor Hypoxia through Unsupervised Modelling of Consumption and Supply Hypoxia MR Imaging in Breast Cancer
Cancers (Basel), 14 (5)
DOI 10.3390/cancers14051326, PubMed 35267636 -
Inhibition of glioma development by doxorubicin-photochemical internalization generated macrophage vaccine: A survival study in rats
Photodiagnosis Photodyn Ther, 38, 102879
DOI 10.1016/j.pdpdt.2022.102879, PubMed 35489691 -
Sonochemical Internalization of Bleomycin Inhibits Adenocarcinoma Breast Tumor Development in an Orthotopic Rat Model
J Environ Pathol Toxicol Oncol, 41 (2), 25-35
DOI 10.1615/JEnvironPatholToxicolOncol.2021040536, PubMed 35695649 -
miR-200a/b/-429 downregulation is a candidate biomarker of tumor radioresistance and independent of hypoxia in locally advanced cervical cancer
Mol Oncol, 16 (6), 1402-1419
DOI 10.1002/1878-0261.13184, PubMed 35064630 -
Are doping tests in sports trustworthy?: Athletes suffer from insufficiently defined criteria for doping tests: Athletes suffer from insufficiently defined criteria for doping tests
EMBO Rep, 23 (3), e54431
DOI 10.15252/embr.202154431, PubMed 35156749 -
Fluid-sensitive migration mechanisms predict association between metastasis and high interstitial fluid pressure in pancreatic cancer
J Biomech, 145, 111362
DOI 10.1016/j.jbiomech.2022.111362, PubMed 36368256 -
A prognostic hypoxia gene signature with low heterogeneity within the dominant tumour lesion in prostate cancer patients
Br J Cancer, 127 (2), 321-328
DOI 10.1038/s41416-022-01782-x, PubMed 35332267 -
Incorporating cross-voxel exchange for the analysis of dynamic contrast-enhanced imaging data: pre-clinical results
Phys Med Biol, 67 (24)
DOI 10.1088/1361-6560/aca512, PubMed 36541560 -
Risk of recurrence after chemoradiotherapy identified by multimodal MRI and 18F-FDG-PET/CT in locally advanced cervical cancer
Radiother Oncol, 176, 17-24
DOI 10.1016/j.radonc.2022.09.002, PubMed 36113778 -
Factors Influencing the Therapeutic Efficacy of the PSMA Targeting Radioligand 212Pb-NG001
Cancers (Basel), 14 (11)
DOI 10.3390/cancers14112784, PubMed 35681766 -
Targeted alpha therapy with the 224Ra/212Pb-TCMC-TP-3 dual alpha solution in a multicellular tumor spheroid model of osteosarcoma
Front Med (Lausanne), 9, 1058863
DOI 10.3389/fmed.2022.1058863, PubMed 36507500 -
Photochemical Internalization of Gemcitabine Is Safe and Effective in Locally Advanced Inoperable Cholangiocarcinoma
Oncologist, 27 (6), 430-e433
DOI 10.1093/oncolo/oyab074, PubMed 35675633 -
All-trans retinoic acid enhances the anti-tumour effects of fimaporfin-based photodynamic therapy
Biomed Pharmacother, 155, 113678
DOI 10.1016/j.biopha.2022.113678, PubMed 36108391
Publications 2021
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Cosegregation of asymmetric features during cell division
Open Biol, 11 (8), 210116
DOI 10.1098/rsob.210116, PubMed 34343465 -
Reactive Species from Two-Signal Activated Macrophages Interfere with Their Oxygen Consumption Measurements
Antioxidants (Basel), 10 (7)
DOI 10.3390/antiox10071149, PubMed 34356382 -
RAB5A expression is a predictive biomarker for trastuzumab emtansine in breast cancer
Nat Commun, 12 (1), 6427
DOI 10.1038/s41467-021-26018-z, PubMed 34741021 -
Assessment of Hypoxic Tissue Fraction and Prediction of Survival in Cervical Carcinoma by Dynamic Contrast-Enhanced MRI
Front Oncol, 11, 668916
DOI 10.3389/fonc.2021.668916, PubMed 34094964 -
Assessment of Intratumor Heterogeneity in Parametric Dynamic Contrast-Enhanced MR Images: A Comparative Study of Novel and Established Methods
Front Oncol, 11, 722773
DOI 10.3389/fonc.2021.722773, PubMed 34621674 -
Intravital microscopy of tumor vessel morphology and function using a standard fluorescence microscope
Eur J Nucl Med Mol Imaging, 48 (10), 3089-3100
DOI 10.1007/s00259-021-05243-0, PubMed 33606081 -
CEP78 functions downstream of CEP350 to control biogenesis of primary cilia by negatively regulating CP110 levels
Elife, 10
DOI 10.7554/eLife.63731, PubMed 34259627 -
The Oslo Cyclotron Laboratory
Eur. Phys. J. Plus, 136 (2), 181
DOI 10.1140/epjp/s13360-021-01150-3 -
Publisher Correction: Proton-dynamic therapy following photosensitiser activation by accelerated protons demonstrated through fluorescence and singlet oxygen production
Nat Commun, 12 (1), 7073
DOI 10.1038/s41467-021-27175-x, PubMed 34848706 -
Expanding roles of cell cycle checkpoint inhibitors in radiation oncology
Int J Radiat Biol, 99 (6), 941-950
DOI 10.1080/09553002.2021.1913529, PubMed 33877959 -
Tumor Hypoxia as a Barrier in Cancer Therapy: Why Levels Matter
Cancers (Basel), 13 (3)
DOI 10.3390/cancers13030499, PubMed 33525508 -
Squamous cell carcinoma of the ear treated by photochemical internalization
Photodiagnosis Photodyn Ther, 36, 102528
DOI 10.1016/j.pdpdt.2021.102528, PubMed 34509683 -
Preclinical and Clinical Status of PSMA-Targeted Alpha Therapy for Metastatic Castration-Resistant Prostate Cancer
Cancers (Basel), 13 (4)
DOI 10.3390/cancers13040779, PubMed 33668474 -
New link between the RNA polymerase II-CTD and replication stress
Mol Cell Oncol, 8 (3), 1910008
DOI 10.1080/23723556.2021.1910008, PubMed 34027044 -
A Novel Single-Step-Labeled 212Pb-CaCO3 Microparticle for Internal Alpha Therapy: Preparation, Stability, and Preclinical Data from Mice
Materials (Basel), 14 (23)
DOI 10.3390/ma14237130, PubMed 34885283 -
Improved Formulation of 224Ra-Labeled Calcium Carbonate Microparticles by Surface Layer Encapsulation and Addition of EDTMP
Pharmaceutics, 13 (5)
DOI 10.3390/pharmaceutics13050634, PubMed 33946852 -
Calcium Carbonate Microparticles as Carriers of 224Ra: Impact of Specific Activity in Mice with Intraperitoneal Ovarian Cancer
Curr Radiopharm, 14 (2), 145-153
DOI 10.2174/1874471013666201201102056, PubMed 33261548 -
Radon-220 diffusion from 224Ra-labeled calcium carbonate microparticles: Some implications for radiotherapeutic use
PLoS One, 16 (3), e0248133
DOI 10.1371/journal.pone.0248133, PubMed 33662039 -
An improved in vitro photochemical internalization protocol for 3D spheroid cultures
Lasers Med Sci, 36 (8), 1567-1571
DOI 10.1007/s10103-021-03332-y, PubMed 34185168 -
Karonudib has potent anti-tumor effects in preclinical models of B-cell lymphoma
Sci Rep, 11 (1), 6317
DOI 10.1038/s41598-021-85613-8, PubMed 33737576 -
Photochemical Internalization Enhanced Vaccination Is Safe, and Gives Promising Cellular Immune Responses to an HPV Peptide-Based Vaccine in a Phase I Clinical Study in Healthy Volunteers
Front Immunol, 11, 576756
DOI 10.3389/fimmu.2020.576756, PubMed 33488576 -
A man in his sixties with dyspnoea following immunotherapy
Tidsskr Nor Laegeforen, 141 (2021-12)
DOI 10.4045/tidsskr.21.0139, PubMed 34505469 -
Differential Effects of Combined ATR/WEE1 Inhibition in Cancer Cells
Cancers (Basel), 13 (15)
DOI 10.3390/cancers13153790, PubMed 34359691 -
Evaluation of the PSMA-Binding Ligand 212Pb-NG001 in Multicellular Tumour Spheroid and Mouse Models of Prostate Cancer
Int J Mol Sci, 22 (9)
DOI 10.3390/ijms22094815, PubMed 34062920 -
Amino acid transporter expression and 18F-FACBC uptake at PET in primary prostate cancer
Am J Nucl Med Mol Imaging, 11 (4), 250-259
PubMed 34513278 -
Efficacy and Selectivity of FGF2-Saporin Cytosolically Delivered by PCI in Cells Overexpressing FGFR1
Cells, 10 (6)
DOI 10.3390/cells10061476, PubMed 34204611 -
In silico investigations of intratumoral heterogeneous interstitial fluid pressure
J Theor Biol, 526, 110787
DOI 10.1016/j.jtbi.2021.110787, PubMed 34087266 -
Inhibiting autophagy increases the efficacy of low-dose photodynamic therapy
Biochem Pharmacol, 194, 114837
DOI 10.1016/j.bcp.2021.114837, PubMed 34780750 -
Light-controlled elimination of PD-L1+ cells
J Photochem Photobiol B, 225, 112355
DOI 10.1016/j.jphotobiol.2021.112355, PubMed 34768077
Publications 2020
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Use of Antidepressants and Risk of Cutaneous Melanoma: A Prospective Registry-Based Case-Control Study
Clin Epidemiol, 12, 193-202
DOI 10.2147/CLEP.S241249, PubMed 32110111 -
Use of Immunomodulating Drugs and Risk of Cutaneous Melanoma: A Nationwide Nested Case-Control Study
Clin Epidemiol, 12, 1389-1401
DOI 10.2147/CLEP.S269446, PubMed 33376408 -
Ra-224 activity, half-life, and 241 keV gamma ray absolute emission intensity: A NIST-NPL bilateral comparison
Appl Radiat Isot, 170, 109572
DOI 10.1016/j.apradiso.2020.109572, PubMed 33461017 -
Production of Recombinant Gelonin Using an Automated Liquid Chromatography System
Toxins (Basel), 12 (8)
DOI 10.3390/toxins12080519, PubMed 32823678 -
Zebrafish Embryos Allow Prediction of Nanoparticle Circulation Times in Mice and Facilitate Quantification of Nanoparticle-Cell Interactions
Small, 16 (5), e1906719
DOI 10.1002/smll.201906719, PubMed 31943784 -
Selective Killing of Activated T Cells by 5-Aminolevulinic Acid Mediated Photodynamic Effect: Potential Improvement of Extracorporeal Photopheresis
Cancers (Basel), 12 (2)
DOI 10.3390/cancers12020377, PubMed 32041351 -
Targeting Telomerase with an HLA Class II-Restricted TCR for Cancer Immunotherapy
Mol Ther, 29 (3), 1199-1213
DOI 10.1016/j.ymthe.2020.11.019, PubMed 33212301 -
Loss of CBY1 results in a ciliopathy characterized by features of Joubert syndrome
Hum Mutat, 41 (12), 2179-2194
DOI 10.1002/humu.24127, PubMed 33131181 -
Combining imaging- and gene-based hypoxia biomarkers in cervical cancer improves prediction of chemoradiotherapy failure independent of intratumour heterogeneity
EBioMedicine, 57, 102841
DOI 10.1016/j.ebiom.2020.102841, PubMed 32580139 -
DCE-MRI of Tumor Hypoxia and Hypoxia-Associated Aggressiveness
Cancers (Basel), 12 (7)
DOI 10.3390/cancers12071979, PubMed 32698525 -
Photodynamic Efficacy of Cercosporin in 3D Tumor Cell Cultures
Photochem Photobiol, 96 (3), 699-707
DOI 10.1111/php.13257, PubMed 32125700 -
Antifibrotic therapy to normalize the tumor microenvironment
J Transl Med, 18 (1), 207
DOI 10.1186/s12967-020-02376-y, PubMed 32434573 -
Transcriptome profiling of human thymic CD4+ and CD8+ T cells compared to primary peripheral T cells
BMC Genomics, 21 (1), 350
DOI 10.1186/s12864-020-6755-1, PubMed 32393182 -
MRI Distinguishes Tumor Hypoxia Levels of Different Prognostic and Biological Significance in Cervical Cancer
Cancer Res, 80 (18), 3993-4003
DOI 10.1158/0008-5472.CAN-20-0950, PubMed 32606004 -
Apparent Complete Response of a Treatment Refractory and Recurrent Squamous Cell Carcinoma Lesion to Photochemical Internalization: A Clinical Case Study
Photochem Photobiol, 96 (3), 680-683
DOI 10.1111/php.13210, PubMed 31901218 -
Photochemical Internalization for Intracellular Drug Delivery. From Basic Mechanisms to Clinical Research
J Clin Med, 9 (2)
DOI 10.3390/jcm9020528, PubMed 32075165 -
Combinatorial CAR design improves target restriction
J Biol Chem, 296, 100116
DOI 10.1074/jbc.RA120.016234, PubMed 33234592 -
WDR82/PNUTS-PP1 Prevents Transcription-Replication Conflicts by Promoting RNA Polymerase II Degradation on Chromatin
Cell Rep, 33 (9), 108469
DOI 10.1016/j.celrep.2020.108469, PubMed 33264625 -
Drug-Loaded Lipid-Coated Hybrid Organic-Inorganic "Stealth" Nanoparticles for Cancer Therapy
Front Bioeng Biotechnol, 8, 1027
DOI 10.3389/fbioe.2020.01027, PubMed 33042960 -
DCE-MRI of locally-advanced carcinoma of the uterine cervix: Tofts analysis versus non-model-based analyses
Radiat Oncol, 15 (1), 79
DOI 10.1186/s13014-020-01526-2, PubMed 32293487 -
177Lu-Lilotomab Satetraxetan Has the Potential to Counteract Resistance to Rituximab in Non-Hodgkin Lymphoma
J Nucl Med, 61 (10), 1468-1475
DOI 10.2967/jnumed.119.237230, PubMed 32245896 -
Predictive biomarkers for 5-ALA-PDT can lead to personalized treatments and overcome tumor-specific resistances
Cancer Rep (Hoboken), 5 (12), e1278
DOI 10.1002/cnr2.1278, PubMed 32737955 -
Radionuclide calibrator responses for 224Ra in solution and adsorbed on calcium carbonate microparticles
Appl Radiat Isot, 164, 109265
DOI 10.1016/j.apradiso.2020.109265, PubMed 32763787 -
Calibration of sodium iodide detectors and reentrant ionization chambers for 212Pb activity in different geometries by HPGe activity determined samples
Appl Radiat Isot, 166, 109362
DOI 10.1016/j.apradiso.2020.109362, PubMed 32979756 -
Photosensitizer delivery by fibrin glue: potential for bypassing the blood-brain barrier
Lasers Med Sci, 36 (5), 1031-1038
DOI 10.1007/s10103-020-03140-w, PubMed 33123852 -
In-Vivo Optical Monitoring of the Efficacy of Epidermal Growth Factor Receptor Targeted Photodynamic Therapy: The Effect of Fluence Rate
Cancers (Basel), 12 (1)
DOI 10.3390/cancers12010190, PubMed 31940973 -
Targeted Photodynamic Therapy of Human Head and Neck Squamous Cell Carcinoma with Anti-epidermal Growth Factor Receptor Antibody Cetuximab and Photosensitizer IR700DX in the Mouse Skin-fold Window Chamber Model
Photochem Photobiol, 96 (3), 708-717
DOI 10.1111/php.13267, PubMed 32222965 -
Cell Cycle Analysis and Relevance for Single-Cell Gating in Mass Cytometry
Cytometry A, 97 (8), 832-844
DOI 10.1002/cyto.a.23960, PubMed 31943748 -
Enhanced gene transfection of macrophages by photochemical internalization: Potential for gene-directed enzyme prodrug therapy of gliomas
Photodiagnosis Photodyn Ther, 33, 102098
DOI 10.1016/j.pdpdt.2020.102098, PubMed 33188941 -
Bevacizumab treatment of meningeal melanoma metastases
J Transl Med, 18 (1), 13
DOI 10.1186/s12967-020-02212-3, PubMed 31915016 -
Photochemical Internalization: Light Paves Way for New Cancer Chemotherapies and Vaccines
Cancers (Basel), 12 (1)
DOI 10.3390/cancers12010165, PubMed 31936595 -
In situ Generated 212Pb-PSMA Ligand in a 224Ra-Solution for Dual Targeting of Prostate Cancer Sclerotic Stroma and PSMA-positive Cells
Curr Radiopharm, 13 (2), 130-141
DOI 10.2174/1874471013666200511000532, PubMed 32389119 -
Preparation of the alpha-emitting prostate-specific membrane antigen targeted radioligand [212 Pb]Pb-NG001 for prostate cancer
J Labelled Comp Radiopharm, 63 (3), 129-143
DOI 10.1002/jlcr.3825, PubMed 31919866 -
Photochemically-Induced Release of Lysosomal Sequestered Sunitinib: Obstacles for Therapeutic Efficacy
Cancers (Basel), 12 (2)
DOI 10.3390/cancers12020417, PubMed 32053965 -
High aldehyde dehydrogenase activity does not protect colon cancer cells against TPCS2a-sensitized photokilling
Photochem Photobiol Sci, 19 (3), 308-312
DOI 10.1039/c9pp00453j, PubMed 32108197
Publications 2019
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Cell-Cycle-Dependent Regulation of Translation: New Interpretations of Old Observations in Light of New Approaches
Bioessays, 41 (8), e1900022
DOI 10.1002/bies.201900022, PubMed 31210378 -
Cardiovascular, antidepressant and immunosuppressive drug use in relation to risk of cutaneous melanoma: a protocol for a prospective case-control study
BMJ Open, 9 (2), e025246
DOI 10.1136/bmjopen-2018-025246, PubMed 30787091 -
eIF2α phosphorylation and the regulation of translation
Curr Genet, 66 (2), 293-297
DOI 10.1007/s00294-019-01026-1, PubMed 31485739 -
A CEP104-CSPP1 Complex Is Required for Formation of Primary Cilia Competent in Hedgehog Signaling
Cell Rep, 28 (7), 1907-1922.e6
DOI 10.1016/j.celrep.2019.07.025, PubMed 31412255 -
Vascularization, Oxygenation, and the Effect of Sunitinib Treatment in Pancreatic Ductal Adenocarcinoma Xenografts
Front Oncol, 9, 845
DOI 10.3389/fonc.2019.00845, PubMed 31555596 -
Proton-dynamic therapy following photosensitiser activation by accelerated protons demonstrated through fluorescence and singlet oxygen production
Nat Commun, 10 (1), 3986
DOI 10.1038/s41467-019-12042-7, PubMed 31484929 -
Intratumor Heterogeneity in Interstitial Fluid Pressure in Cervical and Pancreatic Carcinoma Xenografts
Transl Oncol, 12 (8), 1079-1085
DOI 10.1016/j.tranon.2019.05.012, PubMed 31174058 -
DCE-MRI and Quantitative Histology Reveal Enhanced Vessel Maturation but Impaired Perfusion and Increased Hypoxia in Bevacizumab-Treated Cervical Carcinoma
Int J Radiat Oncol Biol Phys, 104 (3), 666-676
DOI 10.1016/j.ijrobp.2019.03.002, PubMed 30858145 -
p21 limits S phase DNA damage caused by the Wee1 inhibitor MK1775
Cell Cycle, 18 (8), 834-847
DOI 10.1080/15384101.2019.1593649, PubMed 30943845 -
Genomic and functional gene studies suggest a key role of beta-carotene oxygenase 1 like (bco1l) gene in salmon flesh color
Sci Rep, 9 (1), 20061
DOI 10.1038/s41598-019-56438-3, PubMed 31882713 -
Recurrent chondroblastic osteosarcoma of the right mandible subjected to photochemical internalization
Photodiagnosis Photodyn Ther, 27, 288-290
DOI 10.1016/j.pdpdt.2019.06.018, PubMed 31252139 -
Mitochondrial Function of CKS2 Oncoprotein Links Oxidative Phosphorylation with Cell Division in Chemoradioresistant Cervical Cancer
Neoplasia, 21 (4), 353-362
DOI 10.1016/j.neo.2019.01.002, PubMed 30856376 -
Regulation of ATR activity via the RNA polymerase II associated factors CDC73 and PNUTS-PP1
Nucleic Acids Res, 47 (4), 1797-1813
DOI 10.1093/nar/gky1233, PubMed 30541148 -
Pharmacokinetic analysis of DCE-MRI data of locally advanced cervical carcinoma with the Brix model
Acta Oncol, 58 (6), 828-837
DOI 10.1080/0284186X.2019.1580386, PubMed 30810443 -
NK cells specifically TCR-dressed to kill cancer cells
EBioMedicine, 40, 106-117
DOI 10.1016/j.ebiom.2019.01.031, PubMed 30665853 -
Primary standardization of 224Ra activity by liquid scintillation counting
Appl Radiat Isot, 155, 108933
DOI 10.1016/j.apradiso.2019.108933, PubMed 31654881 -
Combination light-based therapies to treat pancreatic cancer: a proof of concept
PROC SPIE, 11070, UNSP 1107045
DOI 10.1117/12.2525305 -
Reference MicroRNAs for RT-qPCR Assays in Cervical Cancer Patients and Their Application to Studies of HPV16 and Hypoxia Biomarkers
Transl Oncol, 12 (3), 576-584
DOI 10.1016/j.tranon.2018.12.010, PubMed 30660934 -
Design, Characterization, and Evaluation of scFvCD133/rGelonin: A CD133-Targeting Recombinant Immunotoxin for Use in Combination with Photochemical Internalization
J Clin Med, 9 (1)
DOI 10.3390/jcm9010068, PubMed 31888091 -
Paclitaxel-loaded biodegradable ROS-sensitive nanoparticles for cancer therapy
Int J Nanomedicine, 14, 6269-6285
DOI 10.2147/IJN.S208938, PubMed 31496685 -
The therapeutic effectiveness of 177Lu-lilotomab in B-cell non-Hodgkin lymphoma involves modulation of G2/M cell cycle arrest
Leukemia, 34 (5), 1315-1328
DOI 10.1038/s41375-019-0677-4, PubMed 31836849 -
Scientific integrity and anti-doping regulation
Int. J. Sport Policy Polit., 11 (2), 295-313
DOI 10.1080/19406940.2019.1596968 -
Scientific integrity and the IAAF testosterone regulations (vol 19, pg 18, 2019)
Int. Sports Law J., 19 (1-2), 27-28
DOI 10.1007/s40318-019-00149-4 -
Scientific integrity and the IAAF testosterone regulations
Int. Sports Law J., 19 (1-2), 18-26
DOI 10.1007/s40318-019-00143-w -
Influx rate of 18F-fluoroaminosuberic acid reflects cystine/glutamate antiporter expression in tumour xenografts
Eur J Nucl Med Mol Imaging, 46 (10), 2190-2198
DOI 10.1007/s00259-019-04375-8, PubMed 31264167 -
The Dual Cell Cycle Kinase Inhibitor JNJ-7706621 Reverses Resistance to CD37-Targeted Radioimmunotherapy in Activated B Cell Like Diffuse Large B Cell Lymphoma Cell Lines
Front Oncol, 9, 1301
DOI 10.3389/fonc.2019.01301, PubMed 31850205 -
The effects of low irradiance long duration photochemical internalization on glioma spheroids
Photodiagnosis Photodyn Ther, 26, 442-447
DOI 10.1016/j.pdpdt.2019.05.005, PubMed 31075319 -
Photochemical Internalization Enhanced Nonviral Suicide Gene Therapy
Methods Mol Biol, 1895, 165-176
DOI 10.1007/978-1-4939-8922-5_13, PubMed 30539537 -
PTEN Expression in Prostate Cancer: Relationship With Clinicopathologic Features and Multiparametric MRI Findings
AJR Am J Roentgenol, 212 (6), 1206-1214
DOI 10.2214/AJR.18.20743, PubMed 30888866 -
Small variations in nanoparticle structure dictate differential cellular stress responses and mode of cell death
Nanotoxicology, 13 (6), 761-782
DOI 10.1080/17435390.2019.1576238, PubMed 30760074 -
Simultaneous defeat of MCF7 and MDA-MB-231 resistances by a hypericin PDT-tamoxifen hybrid therapy
NPJ Breast Cancer, 5, 13
DOI 10.1038/s41523-019-0108-8, PubMed 30993194
Publications 2018
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A novel role for ATR/Rad3 in G1 phase
Sci Rep, 8 (1), 6880
DOI 10.1038/s41598-018-25238-6, PubMed 29720710 -
Outstanding Reviewers for Photochemical and Photobiological Sciences in 2017
Photochem. Photobiol. Sci., 17 (5), 533
DOI 10.1039/c8pp90021c -
Enhanced targeting of triple-negative breast carcinoma and malignant melanoma by photochemical internalization of CSPG4-targeting immunotoxins
Photochem Photobiol Sci, 17 (5), 539-551
DOI 10.1039/C7PP00358G, PubMed 29565434 -
Enhanced Permeability and Retention-like Extravasation of Nanoparticles from the Vasculature into Tuberculosis Granulomas in Zebrafish and Mouse Models
ACS Nano, 12 (8), 8646-8661
DOI 10.1021/acsnano.8b04433, PubMed 30081622 -
Photochemical Internalization of Peptide Antigens Provides a Novel Strategy to Realize Therapeutic Cancer Vaccination
Front Immunol, 9, 650
DOI 10.3389/fimmu.2018.00650, PubMed 29670624 -
Diffusion-Weighted MRI Is Insensitive to Changes in the Tumor Microenvironment Induced by Antiangiogenic Therapy
Transl Oncol, 11 (5), 1128-1136
DOI 10.1016/j.tranon.2018.07.005, PubMed 30036782 -
Photodynamic therapy mediated immune therapy of brain tumors
Neuroimmunol Neuroinflamm, 5
DOI 10.20517/2347-8659.2018.31, PubMed 30221185 -
Combined MR Imaging of Oxygen Consumption and Supply Reveals Tumor Hypoxia and Aggressiveness in Prostate Cancer Patients
Cancer Res, 78 (16), 4774-4785
DOI 10.1158/0008-5472.CAN-17-3806, PubMed 29945958 -
Integrins as therapeutic targets in the organ-specific metastasis of human malignant melanoma
J Exp Clin Cancer Res, 37 (1), 92
DOI 10.1186/s13046-018-0763-x, PubMed 29703238 -
Antitumor Activity of Novel Bone-seeking, α-emitting 224Ra-solution in a Breast Cancer Skeletal Metastases Model
Anticancer Res, 38 (4), 1947-1955
DOI 10.21873/anticanres.12432, PubMed 29599310 -
Transkingdom network reveals bacterial players associated with cervical cancer gene expression program
PeerJ, 6, e5590
DOI 10.7717/peerj.5590, PubMed 30294508 -
Potentials and challenges of diffusion-weighted magnetic resonance imaging in radiotherapy
Clin Transl Radiat Oncol, 13, 29-37
DOI 10.1016/j.ctro.2018.09.002, PubMed 30294681 -
Cytotoxic and Photocytotoxic Effects of Cercosporin on Human Tumor Cell Lines
Photochem Photobiol, 95 (1), 387-396
DOI 10.1111/php.12997, PubMed 30107033 -
Low dose-rate irradiation with [3H]-labelled valine to selectively target hypoxic cells in a human colorectal cancer xenograft model
Acta Oncol, 57 (9), 1216-1224
DOI 10.1080/0284186X.2018.1457223, PubMed 29630428 -
Combination of 177 Lu-lilotomab with rituximab significantly improves the therapeutic outcome in preclinical models of non-Hodgkin's lymphoma
Eur J Haematol, 101 (4), 522-531
DOI 10.1111/ejh.13139, PubMed 29993152 -
The E3 ubiquitin ligase UBR5 regulates centriolar satellite stability and primary cilia
Mol Biol Cell, 29 (13), 1542-1554
DOI 10.1091/mbc.E17-04-0248, PubMed 29742019 -
Functionalized Hyperbranched Polyethylenimines as Thermosensitive Drug Delivery Nanocarriers with Controlled Transition Temperatures
Biomacromolecules, 19 (2), 315-328
DOI 10.1021/acs.biomac.7b01325, PubMed 29313672 -
DCE-MRI-Derived Measures of Tumor Hypoxia and Interstitial Fluid Pressure Predict Outcomes in Cervical Carcinoma
Int J Radiat Oncol Biol Phys, 102 (4), 1193-1201
DOI 10.1016/j.ijrobp.2018.04.035, PubMed 29859790 -
Regulation of global translation during the cell cycle
J Cell Sci, 131 (17)
DOI 10.1242/jcs.220327, PubMed 30072440 -
Comparison of time curves from dynamic 18F-fluciclovine positron emission tomography and dynamic contrast-enhanced magnetic resonance imaging for primary prostate carcinomas
Phys Imaging Radiat Oncol, 7, 51-57
DOI 10.1016/j.phro.2018.09.003, PubMed 33458405 -
Artesunate shows potent anti-tumor activity in B-cell lymphoma
J Hematol Oncol, 11 (1), 23
DOI 10.1186/s13045-018-0561-0, PubMed 29458389 -
Increasing aggressiveness of patient-derived xenograft models of cervix carcinoma during serial transplantation
Oncotarget, 9 (30), 21036-21051
DOI 10.18632/oncotarget.24783, PubMed 29765518 -
DCE-MRI of Sunitinib-Induced Changes in Tumor Microvasculature and Hypoxia: A Study of Pancreatic Ductal Adenocarcinoma Xenografts
Neoplasia, 20 (7), 734-744
DOI 10.1016/j.neo.2018.05.006, PubMed 29886124 -
Ra-224 labeling of calcium carbonate microparticles for internal α-therapy: Preparation, stability, and biodistribution in mice
J Labelled Comp Radiopharm, 61 (6), 472-486
DOI 10.1002/jlcr.3610, PubMed 29380410 -
Light-enhanced VEGF121/rGel: A tumor targeted modality with vascular and immune-mediated efficacy
J Control Release, 288, 161-172
DOI 10.1016/j.jconrel.2018.09.005, PubMed 30217739 -
Mitotic defects in fission yeast lipid metabolism 'cut' mutants are suppressed by ammonium chloride
FEMS Yeast Res, 18 (6)
DOI 10.1093/femsyr/foy064, PubMed 29931271 -
Photochemical internalization enhances cytosolic release of antibiotic and increases its efficacy against staphylococcal infection
J Control Release, 283, 214-222
DOI 10.1016/j.jconrel.2018.06.004, PubMed 29883696
Publications 2017
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Activation of Gcn2 in response to different stresses
PLoS One, 12 (8), e0182143
DOI 10.1371/journal.pone.0182143, PubMed 28771613 -
Lymph node metastasis and the physicochemical micro-environment of pancreatic ductal adenocarcinoma xenografts
Oncotarget, 8 (29), 48060-48074
DOI 10.18632/oncotarget.18231, PubMed 28624797 -
Anti-cancerous effect of albumin coated silver nanoparticles on MDA-MB 231 human breast cancer cell line
Sci Rep, 7 (1), 5178
DOI 10.1038/s41598-017-05461-3, PubMed 28701707 -
Doping and drug testing: Anti-doping work must be transparent and adhere to good scientific practices to ensure public trust
EMBO Rep, 18 (3), 351-354
DOI 10.15252/embr.201643540, PubMed 28167676 -
LUMiC® Endoprosthetic Reconstruction After Periacetabular Tumor Resection: Short-term Results
Clin Orthop Relat Res, 475 (3), 686-695
DOI 10.1007/s11999-016-4805-4, PubMed 27020434 -
Photodynamic therapy enhances the efficacy of gene-directed enzyme prodrug therapy
Photodiagnosis Photodyn Ther, 18, 140-148
DOI 10.1016/j.pdpdt.2017.02.016, PubMed 28257943 -
Role of orexin-2 and CB1 receptors within the periaqueductal gray matter in lateral hypothalamic-induced antinociception in rats
Behav Pharmacol, 28 (1), 83-89
DOI 10.1097/FBP.0000000000000277, PubMed 27906750 -
The Effect of Sunitinib Treatment in Human Melanoma Xenografts: Associations with Angiogenic Profiles
Transl Oncol, 10 (2), 158-167
DOI 10.1016/j.tranon.2016.12.007, PubMed 28167241 -
Antiangiogenic agents targeting different angiogenic pathways have opposite effects on tumor hypoxia in R-18 human melanoma xenografts
BMC Cancer, 17 (1), 411
DOI 10.1186/s12885-017-3404-4, PubMed 28606060 -
Vascular abnormalities and development of hypoxia in microscopic melanoma xenografts
J Transl Med, 15 (1), 241
DOI 10.1186/s12967-017-1347-9, PubMed 29183378 -
Endosome Targeting meso-Tetraphenylchlorin-Chitosan Nanoconjugates for Photochemical Internalization
Biomacromolecules, 18 (4), 1108-1126
DOI 10.1021/acs.biomac.6b01670, PubMed 28245649 -
Photochemical internalization in bladder cancer - development of an orthotopic in vivo model
Photochem Photobiol Sci, 16 (11), 1664-1676
DOI 10.1039/c7pp00176b, PubMed 28972608 -
DCE-MRI of patient-derived xenograft models of uterine cervix carcinoma: associations with parameters of the tumor microenvironment
J Transl Med, 15 (1), 225
DOI 10.1186/s12967-017-1331-4, PubMed 29100521 -
Diffusion-weighted MRI-derived ADC values reflect collagen I content in PDX models of uterine cervical cancer
Oncotarget, 8 (62), 105682-105691
DOI 10.18632/oncotarget.22388, PubMed 29285283 -
Combined inhibition of Wee1 and Chk1 gives synergistic DNA damage in S-phase due to distinct regulation of CDK activity and CDC45 loading
Oncotarget, 8 (7), 10966-10979
DOI 10.18632/oncotarget.14089, PubMed 28030798 -
TLR9 stimulation of B-cells induces transcription of p53 and prevents spontaneous and irradiation-induced cell death independent of DNA damage responses. Implications for Common variable immunodeficiency
PLoS One, 12 (10), e0185708
DOI 10.1371/journal.pone.0185708, PubMed 28973009 -
Metastatic pathway and the microvascular and physicochemical microenvironments of human melanoma xenografts
J Transl Med, 15 (1), 203
DOI 10.1186/s12967-017-1307-4, PubMed 29017512 -
Cancer stem cells (CSCs), cervical CSCs and targeted therapies
Oncotarget, 8 (21), 35351-35367
DOI 10.18632/oncotarget.10169, PubMed 27343550 -
Microenvironmental autophagy promotes tumour growth
Nature, 541 (7637), 417-420
DOI 10.1038/nature20815, PubMed 28077876 -
Dynamic contrast enhanced magnetic resonance imaging for hypoxia mapping and potential for brachytherapy targeting
Phys. Imag. Radiat. Oncol., 2, 1-6
DOI 10.1016/j.phro.2017.03.002 -
MtDNA depletion influences the transition of CD44 subtypes in human prostate cancer DU145 cells
Tumour Biol, 39 (8), 1010428317713671
DOI 10.1177/1010428317713671, PubMed 28789597 -
Metabolic reprogramming is associated with flavopiridol resistance in prostate cancer DU145 cells
Sci Rep, 7 (1), 5081
DOI 10.1038/s41598-017-05086-6, PubMed 28698547 -
5-FU resistant EMT-like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin
J Exp Clin Cancer Res, 36 (1), 187
DOI 10.1186/s13046-017-0662-6, PubMed 29258566 -
Pretreatment late-phase DCE-MRI predicts outcome in locally advanced cervix cancer
Acta Oncol, 56 (5), 675-681
DOI 10.1080/0284186X.2017.1294762, PubMed 28447564 -
Hypoxia in cervical cancer: from biology to imaging
Clin Transl Imaging, 5 (4), 373-388
DOI 10.1007/s40336-017-0238-7, PubMed 28804704 -
Photochemical delivery of bleomycin induces T-cell activation of importance for curative effect and systemic anti-tumor immunity
J Control Release, 268, 120-127
DOI 10.1016/j.jconrel.2017.10.015, PubMed 29042319 -
Impact of genotypic and phenotypic differences in sarcoma models on the outcome of photochemical internalization (PCI) of bleomycin
Photodiagnosis Photodyn Ther, 20, 35-47
DOI 10.1016/j.pdpdt.2017.08.010, PubMed 28838761 -
Development of resistance to photodynamic therapy (PDT) in human breast cancer cells is photosensitizer-dependent: Possible mechanisms and approaches for overcoming PDT-resistance
Biochem Pharmacol, 144, 63-77
DOI 10.1016/j.bcp.2017.08.002, PubMed 28784290 -
Molecular Mechanisms of UVA-Induced Melanoma
J Environ Pathol Toxicol Oncol, 36 (3), 217-228
DOI 10.1615/JEnvironPatholToxicolOncol.2017020213, PubMed 29283335 -
A checkpoint-independent mechanism delays entry into mitosis after UV irradiation
J Cell Sci, 130 (23), 4028-4037
DOI 10.1242/jcs.204693, PubMed 29046339 -
Human Adipose-Derived Mesenchymal Stem Cells Respond to Short-Term Hypoxia by Secreting Factors Beneficial for Human Islets In Vitro and Potentiate Antidiabetic Effect In Vivo
Cell Med, 9 (3), 103-116
DOI 10.3727/215517917X693401, PubMed 28713640 -
Photochemical internalization (PCI) of bleomycin is equally effective in two dissimilar leiomyosarcoma xenografts in athymic mice
Photodiagnosis Photodyn Ther, 20, 95-106
DOI 10.1016/j.pdpdt.2017.08.015, PubMed 28865875 -
Photochemical internalization enhanced macrophage delivered chemotherapy
Photodiagnosis Photodyn Ther, 21, 156-162
DOI 10.1016/j.pdpdt.2017.12.002, PubMed 29221858 -
The diverse roles of glutathione-associated cell resistance against hypericin photodynamic therapy
Redox Biol, 12, 191-197
DOI 10.1016/j.redox.2017.02.018, PubMed 28254657 -
Autodelineation of cervical cancers using multiparametric magnetic resonance imaging and machine learning
Acta Oncol, 56 (6), 806-812
DOI 10.1080/0284186X.2017.1285499, PubMed 28464746 -
Dynamic contrast-enhanced MRI of the microenvironment of pancreatic adenocarcinoma xenografts
Acta Oncol, 56 (12), 1754-1762
DOI 10.1080/0284186X.2017.1343494, PubMed 28661213
Publications 2016
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Consequences of abnormal CDK activity in S phase
Cell Cycle, 15 (7), 963-73
DOI 10.1080/15384101.2016.1152423, PubMed 26918805 -
Differential propagation of stroma and cancer stem cells dictates tumorigenesis and multipotency
Oncogene, 36 (4), 570-584
DOI 10.1038/onc.2016.230, PubMed 27345406 -
Analyzing Schizosaccharomyces pombe DNA Content by Flow Cytometry
Cold Spring Harb Protoc, 2016 (6)
DOI 10.1101/pdb.prot091280, PubMed 27250946 -
Synergistic chemotherapy by combined moderate hyperthermia and photochemical internalization
Biomed Opt Express, 7 (4), 1240-50
DOI 10.1364/BOE.7.001240, PubMed 27446650 -
Integrative Analysis of DCE-MRI and Gene Expression Profiles in Construction of a Gene Classifier for Assessment of Hypoxia-Related Risk of Chemoradiotherapy Failure in Cervical Cancer
Clin Cancer Res, 22 (16), 4067-76
DOI 10.1158/1078-0432.CCR-15-2322, PubMed 27012812 -
Identification and Validation of Reference Genes for RT-qPCR Studies of Hypoxia in Squamous Cervical Cancer Patients
PLoS One, 11 (5), e0156259
DOI 10.1371/journal.pone.0156259, PubMed 27244197 -
Individual tumor volume responses to short-course oxaliplatin-containing induction chemotherapy in locally advanced rectal cancer - Targeting the tumor for radiation sensitivity?
Radiother Oncol, 119 (3), 505-11
DOI 10.1016/j.radonc.2016.02.020, PubMed 26968754 -
Properdistatin inhibits angiogenesis and improves vascular function in human melanoma xenografts with low thrombospondin-1 expression
Oncotarget, 7 (47), 76806-76815
DOI 10.18632/oncotarget.12695, PubMed 27756886 -
Do studies reporting 'U'-shaped serum 25-hydroxyvitamin D-health outcome relationships reflect adverse effects?
Dermatoendocrinol, 8 (1), e1187349
DOI 10.1080/19381980.2016.1187349, PubMed 27489574 -
Layer Thickness of SPF 30 Sunscreen and Formation of Pre-vitamin D
Anticancer Res, 36 (3), 1409-15
PubMed 26977044 -
The influence of photodynamic therapy with 5-aminolevulinic acid on senescent skin cancer cells
Photodiagnosis Photodyn Ther, 17, 29-34
DOI 10.1016/j.pdpdt.2016.10.008, PubMed 27777143 -
Hypoxia-induced alterations of G2 checkpoint regulators
Mol Oncol, 10 (5), 764-73
DOI 10.1016/j.molonc.2015.12.015, PubMed 26791779 -
Cytosolic Delivery of Liposomal Vaccines by Means of the Concomitant Photosensitization of Phagosomes
Mol Pharm, 13 (2), 320-9
DOI 10.1021/acs.molpharmaceut.5b00394, PubMed 26704885 -
Hypoxia-independent gene expression signature associated with radiosensitisation of prostate cancer cell lines by histone deacetylase inhibition
Br J Cancer, 115 (8), 929-939
DOI 10.1038/bjc.2016.278, PubMed 27599042 -
Phototherapy and vitamin D
Clin Dermatol, 34 (5), 548-55
DOI 10.1016/j.clindermatol.2016.05.004, PubMed 27638432 -
Folic acid and its photoproducts, 6-formylpterin and pterin-6-carboxylic acid, as generators of reactive oxygen species in skin cells during UVA exposure
J Photochem Photobiol B, 155, 116-21
DOI 10.1016/j.jphotobiol.2016.01.001, PubMed 26780587 -
Repositioning of Drugs in Cardiometabolic Disorders: Importance and Current Scenario
Curr Top Med Chem, 16 (19), 2189-200
DOI 10.2174/1568026616666160216152138, PubMed 26881721 -
MtDNA depleted PC3 cells exhibit Warburg effect and cancer stem cell features
Oncotarget, 7 (26), 40297-40313
DOI 10.18632/oncotarget.9610, PubMed 27248169 -
Comparing the Effects of Light- or Sonic-Activated Drug Delivery: Photochemical/Sonochemical Internalization
J Environ Pathol Toxicol Oncol, 35 (1), 91-8
DOI 10.1615/JEnvironPatholToxicolOncol.2016015463, PubMed 27279586 -
Biologic Effects of Light: An Enlighting Prospective
Anticancer Res, 36 (3), 1339-43
PubMed 26977035 -
Functional intratumoral lymphatics in patient-derived xenograft models of squamous cell carcinoma of the uterine cervix: implications for lymph node metastasis
Oncotarget, 7 (35), 56986-56997
DOI 10.18632/oncotarget.10931, PubMed 27486768 -
Patient-derived xenograft models of squamous cell carcinoma of the uterine cervix
Cancer Lett, 373 (2), 147-55
DOI 10.1016/j.canlet.2016.01.047, PubMed 26828134 -
Intracranial Tumor Cell Migration and the Development of Multiple Brain Metastases in Malignant Melanoma
Transl Oncol, 9 (3), 211-8
DOI 10.1016/j.tranon.2016.04.003, PubMed 27267839 -
Disulfonated tetraphenyl chlorin (TPCS2a)-induced photochemical internalisation of bleomycin in patients with solid malignancies: a phase 1, dose-escalation, first-in-man trial
Lancet Oncol, 17 (9), 1217-29
DOI 10.1016/S1470-2045(16)30224-8, PubMed 27475428 -
Cluster analysis of dynamic contrast enhanced MRI reveals tumor subregions related to locoregional relapse for cervical cancer patients
Acta Oncol, 55 (11), 1294-1298
DOI 10.1080/0284186X.2016.1189091, PubMed 27564398 -
Diffusion-weighted and dynamic contrast-enhanced MRI of pancreatic adenocarcinoma xenografts: associations with tumor differentiation and collagen content
J Transl Med, 14 (1), 161
DOI 10.1186/s12967-016-0920-y, PubMed 27268062 -
Aberrant methylation-mediated silencing of microRNAs contributes to HPV-induced anchorage independence
Oncotarget, 7 (28), 43805-43819
DOI 10.18632/oncotarget.9698, PubMed 27270309 -
Role of orexin-2 receptors in the nucleus accumbens in antinociception induced by carbachol stimulation of the lateral hypothalamus in formalin test
Behav Pharmacol, 27 (5), 431-8
DOI 10.1097/FBP.0000000000000216, PubMed 26871404
Publications 2015
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Studies of the photosensitizer disulfonated meso-tetraphenyl chlorin in an orthotopic rat bladder tumor model
Photodiagnosis Photodyn Ther, 12 (1), 58-66
DOI 10.1016/j.pdpdt.2014.12.005, PubMed 25575731 -
Resistance mechanisms in photodynamic therapy
Photochem Photobiol Sci, 14 (8), 1376-7
DOI 10.1039/c5pp90026c, PubMed 26212047 -
Design of an EGFR-targeting toxin for photochemical delivery: in vitro and in vivo selectivity and efficacy
Oncogene, 34 (44), 5582-92
DOI 10.1038/onc.2015.15, PubMed 25684137 -
Light-controlled endosomal escape of the novel CD133-targeting immunotoxin AC133-saporin by photochemical internalization - A minimally invasive cancer stem cell-targeting strategy
J Control Release, 206, 37-48
DOI 10.1016/j.jconrel.2015.03.008, PubMed 25758331 -
Photosensitizer and Light Pave the Way for Cytosolic Targeting and Generation of Cytosolic CD8 T Cells Using PLGA Vaccine Particles
J Immunol, 195 (1), 166-73
DOI 10.4049/jimmunol.1500431, PubMed 26019274 -
Photochemical activation of MH3-B1/rGel: a HER2-targeted treatment approach for ovarian cancer
Oncotarget, 6 (14), 12436-51
DOI 10.18632/oncotarget.3814, PubMed 26002552 -
Macrophage mediated PCI enhanced gene-directed enzyme prodrug therapy
PROC SPIE, 9305
DOI 10.1117/12.2082590 -
Supramolecular nanoscale assemblies for cancer diagnosis and therapy
J Control Release, 213, 152-167
DOI 10.1016/j.jconrel.2015.06.034, PubMed 26160308 -
Replication-induced DNA damage after PARP inhibition causes G2 delay, and cell line-dependent apoptosis, necrosis and multinucleation
Cell Cycle, 14 (20), 3248-60
DOI 10.1080/15384101.2015.1085137, PubMed 26312527 -
New distinct compartments in the G2 phase of the cell cycle defined by the levels of γH2AX
Cell Cycle, 14 (20), 3261-9
DOI 10.1080/15384101.2015.1087617, PubMed 26317799 -
TGF-B3 Dependent Modification of Radiosensitivity in Reporter Cells Exposed to Serum From Whole-Body Low Dose-Rate Irradiated Mice
Dose Response, 13 (1)
DOI 10.2203/dose-response.14-015.Edin, PubMed 26673923 -
Hypoxia biomarkers in squamous cell carcinoma of the uterine cervix
BMC Cancer, 15, 805
DOI 10.1186/s12885-015-1828-2, PubMed 26502718 -
Early effects of low dose bevacizumab treatment assessed by magnetic resonance imaging
BMC Cancer, 15, 900
DOI 10.1186/s12885-015-1918-1, PubMed 26573613 -
Photochemical internalization of bleomycin and temozolomide--in vitro studies on the glioma cell line F98
Photochem Photobiol Sci, 14 (7), 1357-66
DOI 10.1039/c5pp00144g, PubMed 26088711 -
Radiosensitizing effect of zinc oxide and silica nanocomposites on cancer cells
Colloids Surf B Biointerfaces, 129, 79-86
DOI 10.1016/j.colsurfb.2015.03.026, PubMed 25829130 -
Identification of Metastasis-Associated Metabolic Profiles of Tumors by (1)H-HR-MAS-MRS
Neoplasia, 17 (10), 767-75
DOI 10.1016/j.neo.2015.10.001, PubMed 26585232 -
Vitamin D and ultraviolet phototherapy in Caucasians
J Photochem Photobiol B, 147, 69-74
DOI 10.1016/j.jphotobiol.2015.03.009, PubMed 25846579 -
Daily, seasonal, and latitudinal variations in solar ultraviolet A and B radiation in relation to vitamin D production and risk for skin cancer
Int J Dermatol, 55 (1), e23-8
DOI 10.1111/ijd.13065, PubMed 26547141 -
Combined concurrent nanoshell loaded macrophage-mediated photothermal and photodynamic therapies
PROC SPIE, 9303, 930322
DOI 10.1117/12.2082850 -
Mitochondrial DNA Deficiency in Ovarian Cancer Cells and Cancer Stem Cell-like Properties
Anticancer Res, 35 (7), 3743-53
PubMed 26124317 -
Simultaneous measurement of passage through the restriction point and MCM loading in single cells
Nucleic Acids Res, 43 (22), e150
DOI 10.1093/nar/gkv744, PubMed 26250117 -
Influence of multiple UV exposures on serum cobalamin and vitamin D levels in healthy females
Scand J Public Health, 43 (3), 324-30
DOI 10.1177/1403494815572206, PubMed 25740614 -
Vitamin D levels and dietary intake among patients with benign soft tissue tumors and sarcomas
Anticancer Res, 35 (2), 1171-80
PubMed 25667508 -
Stress-induced inhibition of translation independently of eIF2α phosphorylation
J Cell Sci, 128 (23), 4420-7
DOI 10.1242/jcs.176545, PubMed 26493332 -
Interplay between promoter methylation and chromosomal loss in gene silencing at 3p11-p14 in cervical cancer
Epigenetics, 10 (10), 970-80
DOI 10.1080/15592294.2015.1085140, PubMed 26291246 -
Short-term pretreatment DCE-MRI in prediction of outcome in locally advanced cervical cancer
Radiother Oncol, 115 (3), 379-85
DOI 10.1016/j.radonc.2015.05.001, PubMed 25998804 -
Combined inhibition of the cell cycle related proteins Wee1 and Chk1/2 induces synergistic anti-cancer effect in melanoma
BMC Cancer, 15, 462
DOI 10.1186/s12885-015-1474-8, PubMed 26054341 -
A Family of Potent Ru(II) Photosensitizers with Enhanced DNA Intercalation: Bimodal Photokillers
Photochem Photobiol, 91 (5), 1191-202
DOI 10.1111/php.12485, PubMed 26118404 -
Targeted Cancer Therapy with a Novel Anti-CD37 Beta-Particle Emitting Radioimmunoconjugate for Treatment of Non-Hodgkin Lymphoma
PLoS One, 10 (6), e0128816
DOI 10.1371/journal.pone.0128816, PubMed 26066655 -
MRI volumetry for prediction of tumour response to neoadjuvant chemotherapy followed by chemoradiotherapy in locally advanced rectal cancer
Br J Radiol, 88 (1051), 20150097
DOI 10.1259/bjr.20150097, PubMed 25899892 -
Photochemical internalisation, a minimally invasive strategy for light-controlled endosomal escape of cancer stem cell-targeting therapeutics
Photochem Photobiol Sci, 14 (8), 1433-50
DOI 10.1039/c5pp00027k, PubMed 25805311 -
Intertumor heterogeneity in vascularity and invasiveness of artificial melanoma brain metastases
J Exp Clin Cancer Res, 34, 150
DOI 10.1186/s13046-015-0264-0, PubMed 26667022 -
CSPP-L Associates with the Desmosome of Polarized Epithelial Cells and Is Required for Normal Spheroid Formation
PLoS One, 10 (8), e0134789
DOI 10.1371/journal.pone.0134789, PubMed 26241740 -
Targeting lung cancer through inhibition of checkpoint kinases
Front Genet, 6, 70
DOI 10.3389/fgene.2015.00070, PubMed 25774168 -
Deciphering the Nongenomic, Mitochondrial Toxicity of Tamoxifens As Determined by Cell Metabolism and Redox Activity
ACS Chem Biol, 11 (1), 251-62
DOI 10.1021/acschembio.5b00734, PubMed 26569462 -
Photochemical activation of drugs for the treatment of therapy-resistant cancers
Photochem Photobiol Sci, 14 (8), 1465-75
DOI 10.1039/c5pp00029g, PubMed 25849953
Publications 2014
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Light-triggered, efficient cytosolic release of IM7-saporin targeting the putative cancer stem cell marker CD44 by photochemical internalization
Mol Pharm, 11 (8), 2764-76
DOI 10.1021/mp500129t, PubMed 24960585 -
Photochemical activation of the recombinant HER2-targeted fusion toxin MH3-B1/rGel; Impact of HER2 expression on treatment outcome
J Control Release, 182, 58-66
DOI 10.1016/j.jconrel.2014.03.014, PubMed 24637464 -
Enhancing proteasome-lnhibitor effect by functionalized gold nanoparticles
J Biomed Nanotechnol, 10 (4), 717-23
DOI 10.1166/jbn.2014.1743, PubMed 24734524 -
The roles of TGF-β3 and peroxynitrite in removal of hyper-radiosensitivity by priming irradiation
Int J Radiat Biol, 90 (7), 527-37
DOI 10.3109/09553002.2014.906767, PubMed 24650070 -
Thrombospondin-1 domain-containing peptide properdistatin improves vascular function in human melanoma xenografts
Microvasc Res, 98, 159-65
DOI 10.1016/j.mvr.2014.02.005, PubMed 24555949 -
Differential DNA methylation analysis of breast cancer reveals the impact of immune signaling in radiation therapy
Int J Cancer, 135 (9), 2085-95
DOI 10.1002/ijc.28862, PubMed 24658971 -
DW-MRI in assessment of the hypoxic fraction, interstitial fluid pressure, and metastatic propensity of melanoma xenografts
BMC Cancer, 14, 92
DOI 10.1186/1471-2407-14-92, PubMed 24528854 -
Peritumoral interstitial fluid flow velocity predicts survival in cervical carcinoma
Radiother Oncol, 113 (1), 132-8
DOI 10.1016/j.radonc.2014.09.011, PubMed 25443501 -
Photosensitisation facilitates cross-priming of adjuvant-free protein vaccines and stimulation of tumour-suppressing CD8 T cells
J Control Release, 198, 10-7
DOI 10.1016/j.jconrel.2014.11.032, PubMed 25482339 -
Sun exposure and melanomas on sun-shielded and sun-exposed body areas
Adv Exp Med Biol, 810, 375-89
DOI 10.1007/978-1-4939-0437-2_21, PubMed 25207377 -
Minimal and maximal incidence rates of skin cancer in Caucasians estimated by use of sigmoidal UV dose-incidence curves
Int J Hyg Environ Health, 217 (8), 839-44
DOI 10.1016/j.ijheh.2014.06.002, PubMed 25023193 -
PLK1-inhibition can cause radiosensitization or radioresistance dependent on the treatment schedule
Radiother Oncol, 110 (2), 355-61
DOI 10.1016/j.radonc.2013.12.014, PubMed 24502970 -
The novel EpCAM-targeting monoclonal antibody 3-17I linked to saporin is highly cytotoxic after photochemical internalization in breast, pancreas and colon cancer cell lines
MAbs, 6 (4), 1038-50
DOI 10.4161/mabs.28207, PubMed 24525727 -
The relationship between UV exposure and incidence of skin cancer
Photodermatol Photoimmunol Photomed, 31 (1), 26-35
DOI 10.1111/phpp.12139, PubMed 25213656 -
Ultraviolet-radiation and health: optimal time for sun exposure
Adv Exp Med Biol, 810, 423-8
PubMed 25207380 -
Ultraviolet radiation and cutaneous malignant melanoma
Adv Exp Med Biol, 810, 359-74
DOI 10.1007/978-1-4939-0437-2_20, PubMed 25207376 -
Associations between tumor vascularization assessed by in vivo DCE-MRI and the presence of disseminated tumor cells in bone marrow in breast cancer patients at the time of diagnosis
J Magn Reson Imaging, 40 (6), 1382-91
DOI 10.1002/jmri.24502, PubMed 24470360 -
Carboxylated hydroxyethyl starch: a novel polysaccharide for the delivery of doxorubicin
Chem Biol Drug Des, 85 (5), 653-8
DOI 10.1111/cbdd.12447, PubMed 25303215 -
Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium
J Enzyme Inhib Med Chem, 30 (5), 689-721
DOI 10.3109/14756366.2014.966704, PubMed 25347767 -
The tumour hypoxia marker pimonidazole reflects a transcriptional programme associated with aggressive prostate cancer
Br J Cancer, 112 (2), 382-90
DOI 10.1038/bjc.2014.604, PubMed 25461803 -
177Lu-DOTA-HH1, a novel anti-CD37 radio-immunoconjugate: a study of toxicity in nude mice
PLoS One, 9 (7), e103070
DOI 10.1371/journal.pone.0103070, PubMed 25068508 -
Tumor interstitial fluid pressure-a link between tumor hypoxia, microvascular density, and lymph node metastasis
Neoplasia, 16 (7), 586-94
DOI 10.1016/j.neo.2014.07.003, PubMed 25117980 -
Ménage à trois: an evolutionary interplay between human papillomavirus, a tumor, and a woman
Trends Microbiol, 22 (6), 345-53
DOI 10.1016/j.tim.2014.02.009, PubMed 24674660 -
Nuclear CSPP1 expression defined subtypes of basal-like breast cancer
Br J Cancer, 111 (2), 326-38
DOI 10.1038/bjc.2014.297, PubMed 24901235 -
Classification of dynamic contrast enhanced MR images of cervical cancers using texture analysis and support vector machines
IEEE Trans Med Imaging, 33 (8), 1648-56
DOI 10.1109/TMI.2014.2321024, PubMed 24802069 -
Photochemical internalization (PCI) enhanced nonviral transfection of tumor suppressor and pro-drug activating genes; a potential treatment modality for gliomas.
PROC SPIE, 8928, 89280B
DOI 10.1117/12.2041627 -
Increased sensitivity of glioma cells to 5-fluorocytosine following photo-chemical internalization enhanced nonviral transfection of the cytosine deaminase suicide gene
J Neurooncol, 118 (1), 29-37
DOI 10.1007/s11060-014-1410-9, PubMed 24610460 -
Photochemical internalization augments tumor vascular cytotoxicity and specificity of VEGF(121)/rGel fusion toxin
J Control Release, 180, 1-9
DOI 10.1016/j.jconrel.2014.02.003, PubMed 24531010 -
Photochemical internalization-mediated nonviral gene transfection: polyamine core-shell nanoparticles as gene carrier
J Biomed Opt, 19 (10), 105009
DOI 10.1117/1.JBO.19.10.105009, PubMed 25341069 -
X-ray-induced nanoparticle-based photodynamic therapy of cancer
Nanomedicine (Lond), 9 (15), 2339-51
DOI 10.2217/nnm.13.198, PubMed 24471504
Publications 2013
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Comparing high LET 227Th- and low LET 177Lu-trastuzumab in mice with HER-2 positive SKBR-3 xenografts
Curr Radiopharm, 6 (2), 78-86
DOI 10.2174/18744710113069990017, PubMed 23551110 -
Pharmacokinetic parameters derived from dynamic contrast enhanced MRI of cervical cancers predict chemoradiotherapy outcome
Radiother Oncol, 107 (1), 117-22
DOI 10.1016/j.radonc.2012.11.007, PubMed 23333024 -
Photochemical internalization (PCI) of immunotoxins targeting CD133 is specific and highly potent at femtomolar levels in cells with cancer stem cell properties
J Control Release, 168 (3), 317-26
DOI 10.1016/j.jconrel.2013.03.023, PubMed 23567040 -
Gold nanoparticle delivery-enhanced proteasome inhibitor effect in adenocarcinoma cells
Expert Opin Drug Deliv, 10 (10), 1345-52
DOI 10.1517/17425247.2013.827659, PubMed 23937147 -
The role of nitric oxide radicals in removal of hyper-radiosensitivity by priming irradiation
J Radiat Res, 54 (6), 1015-28
DOI 10.1093/jrr/rrt061, PubMed 23685670 -
DCE-MRI of the hypoxic fraction, radioresponsiveness, and metastatic propensity of cervical carcinoma xenografts
Radiother Oncol, 110 (2), 335-41
DOI 10.1016/j.radonc.2013.10.018, PubMed 24231244 -
The Microenvironment of Cervical Carcinoma Xenografts: Associations with Lymph Node Metastasis and Its Assessment by DCE-MRI
Transl Oncol, 6 (5), 607-17
DOI 10.1593/tlo.13313, PubMed 24151541 -
Karyotyping of diffuse large B-cell lymphomas: loss of 17p is associated with poor patient outcome
Eur J Haematol, 91 (4), 332-8
DOI 10.1111/ejh.12171, PubMed 23859481 -
Magnetic resonance imaging identifies early effects of sunitinib treatment in human melanoma xenografts
J Exp Clin Cancer Res, 32 (1), 93
DOI 10.1186/1756-9966-32-93, PubMed 24245934 -
Tetraphenylporphyrin tethered chitosan based carriers for photochemical transfection
J Med Chem, 56 (3), 807-19
DOI 10.1021/jm301270r, PubMed 23281854 -
Biologically efficient solar radiation: Vitamin D production and induction of cutaneous malignant melanoma
Dermatoendocrinol, 5 (1), 150-8
DOI 10.4161/derm.22941, PubMed 24494048 -
The efficacy of CHK1 inhibitors is not altered by hypoxia, but is enhanced after reoxygenation
Mol Cancer Ther, 12 (5), 705-16
DOI 10.1158/1535-7163.MCT-12-0879, PubMed 23635654 -
Targeted alpha therapy with 227Th-trastuzumab of intraperitoneal ovarian cancer in nude mice
Curr Radiopharm, 6 (2), 106-16
DOI 10.2174/18744710113069990018, PubMed 23551111 -
Modifications in dynamic contrast-enhanced magnetic resonance imaging parameters after α-particle-emitting ²²⁷Th-trastuzumab therapy of HER2-expressing ovarian cancer xenografts
Int J Radiat Oncol Biol Phys, 87 (1), 153-9
DOI 10.1016/j.ijrobp.2013.04.052, PubMed 23790511 -
Connective tissue of cervical carcinoma xenografts: associations with tumor hypoxia and interstitial fluid pressure and its assessment by DCE-MRI and DW-MRI
Acta Oncol, 53 (1), 6-15
DOI 10.3109/0284186X.2013.773073, PubMed 23445339 -
Intradermal photosensitisation facilitates stimulation of MHC class-I restricted CD8 T-cell responses of co-administered antigen
J Control Release, 174, 143-50
DOI 10.1016/j.jconrel.2013.11.017, PubMed 24280261 -
Photoactivatable carbon nanodots for cancer therapy
Appl. Phys. Lett., 103 (6), 063701
DOI 10.1063/1.4817787 -
Clearance mechanism of protoporphyrin IX from mouse skin after application of 5-aminolevulinic acid
Photodiagnosis Photodyn Ther, 10 (4), 538-45
DOI 10.1016/j.pdpdt.2013.05.008, PubMed 24284108 -
Photodegradation of cobalamins in aqueous solutions and in human blood
J Photochem Photobiol B, 122, 7-14
DOI 10.1016/j.jphotobiol.2013.03.001, PubMed 23558034 -
The action spectrum for folic acid photodegradation in aqueous solutions
J Photochem Photobiol B, 126, 11-6
DOI 10.1016/j.jphotobiol.2013.05.011, PubMed 23892004 -
Extracting fuzzy classification rules from texture segmented HRCT lung images
J Digit Imaging, 26 (2), 227-38
DOI 10.1007/s10278-012-9514-2, PubMed 22890442 -
Carbon-core silver-shell nanodots as sensitizers for phototherapy and radiotherapy
Nanotechnology, 24 (32), 325103
DOI 10.1088/0957-4484/24/32/325103, PubMed 23868054 -
Dynamic (18) F-FDG PET for Assessment of Tumor Physiology in Two Breast Carcinoma Xenografts
Nucl Med Mol Imaging, 47 (3), 173-80
DOI 10.1007/s13139-013-0211-y, PubMed 24900104 -
Effect of vitamin D supplementation and ultraviolet B exposure on serum 25-hydroxyvitamin D concentrations in healthy volunteers: a randomized, crossover clinical trial
Br J Dermatol, 169 (2), 434-40
DOI 10.1111/bjd.12349, PubMed 23551243 -
Identification of eight candidate target genes of the recurrent 3p12-p14 loss in cervical cancer by integrative genomic profiling
J Pathol, 230 (1), 59-69
DOI 10.1002/path.4168, PubMed 23335387 -
Gene network reconstruction reveals cell cycle and antiviral genes as major drivers of cervical cancer
Nat Commun, 4, 1806
DOI 10.1038/ncomms2693, PubMed 23651994 -
Cutaneous malignant melanoma incidence rates in Norway
Scand J Public Health, 41 (4), 336-9
DOI 10.1177/1403494813479216, PubMed 23439631 -
North-South gradients of melanomas and non-melanomas: A role of vitamin D?
Dermatoendocrinol, 5 (1), 186-91
DOI 10.4161/derm.23791, PubMed 24494053 -
Sunbed use and cutaneous melanoma in Norway
Scand J Public Health, 41 (8), 812-7
DOI 10.1177/1403494813496601, PubMed 23907734 -
Circumvention of resistance to photodynamic therapy in doxorubicin-resistant sarcoma by photochemical internalization of gelonin
Free Radic Biol Med, 65, 1300-1309
DOI 10.1016/j.freeradbiomed.2013.09.010, PubMed 24076428 -
Increase in serum 25-hydroxyvitamin-D3 in humans after sunbed exposures compared to previtamin D3 synthesis in vitro
J Photochem Photobiol B, 122, 32-6
DOI 10.1016/j.jphotobiol.2013.03.006, PubMed 23591142 -
Hypoxia-independent downregulation of hypoxia-inducible factor 1 targets by androgen deprivation therapy in prostate cancer
Int J Radiat Oncol Biol Phys, 87 (4), 753-60
DOI 10.1016/j.ijrobp.2013.07.023, PubMed 24035332 -
Biodistribution and dosimetry of (177)Lu-tetulomab, a new radioimmunoconjugate for treatment of non-Hodgkin lymphoma
Curr Radiopharm, 6 (1), 20-7
DOI 10.2174/1874471011306010004, PubMed 23256748 -
Hypoxic tumor kinase signaling mediated by STAT5A in development of castration-resistant prostate cancer
PLoS One, 8 (5), e63723
DOI 10.1371/journal.pone.0063723, PubMed 23675504 -
The influence of Pluronics® on dark cytotoxicity, photocytotoxicity, localization and uptake of curcumin in cancer cells: studies of curcumin and curcuminoids XLIX
Photochem Photobiol Sci, 12 (3), 559-75
DOI 10.1039/c2pp25249j, PubMed 23108412 -
The influence of Pluronics nanovehicles on dark cytotoxicity, photocytotoxicity and localization of four model photosensitizers in cancer cells
Photochem Photobiol Sci, 13 (1), 8-22
DOI 10.1039/c3pp50181g, PubMed 24158176 -
Photochemical internalization of CD133-targeting immunotoxins efficiently depletes sarcoma cells with stem-like properties and reduces tumorigenicity
Biochim Biophys Acta, 1830 (8), 4235-43
DOI 10.1016/j.bbagen.2013.04.033, PubMed 23643966 -
The photosensitizer disulfonated aluminum phthalocyanine reduces uptake and alters trafficking of fluid phase endocytosed drugs in vascular endothelial cells--impact on efficacy of photochemical internalization
Biochem Pharmacol, 86 (6), 748-58
DOI 10.1016/j.bcp.2013.07.011, PubMed 23876343 -
Vascular endothelial cells as targets for photochemical internalization (PCI)
Photochem Photobiol, 89 (5), 1185-92
DOI 10.1111/php.12126, PubMed 23819771 -
Identification and characterization of cells with cancer stem cell properties in human primary lung cancer cell lines
PLoS One, 8 (3), e57020 (Retracted)
DOI 10.1371/journal.pone.0057020, PubMed 23469181 -
Sustained ERK inhibition by EGFR targeting therapies is a predictive factor for synergistic cytotoxicity with PDT as neoadjuvant therapy (vol 1830, pg 2659, 2013)
Biochim. Biophys. Acta-Gen. Subj., 1830 (10), 4417
DOI 10.1016/j.bbagen.2013.05.002 -
Sustained ERK [corrected] inhibition by EGFR targeting therapies is a predictive factor for synergistic cytotoxicity with PDT as neoadjuvant therapy
Biochim Biophys Acta, 1830 (3), 2659-70
DOI 10.1016/j.bbagen.2012.11.010, PubMed 23671927
Publications 2012
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Preclinical evaluation of 227Th-labeled and 177Lu-labeled trastuzumab in mice with HER-2-positive ovarian cancer xenografts
Nucl Med Commun, 33 (8), 838-47
DOI 10.1097/MNM.0b013e328354df7c, PubMed 22643311 -
Epidermal growth factor receptor-targeted photosensitizer selectively inhibits EGFR signaling and induces targeted phototoxicity in ovarian cancer cells
Cancer Lett, 321 (2), 120-7
DOI 10.1016/j.canlet.2012.01.014, PubMed 22266098 -
Cyclin-dependent kinase suppression by WEE1 kinase protects the genome through control of replication initiation and nucleotide consumption
Mol Cell Biol, 32 (20), 4226-36
DOI 10.1128/MCB.00412-12, PubMed 22907750 -
Photochemical internalization (PCI) of HER2-targeted toxins: synergy is dependent on the treatment sequence
Biochim Biophys Acta, 1820 (12), 1849-58
DOI 10.1016/j.bbagen.2012.08.027, PubMed 22981913 -
Occupational radiation exposure in health care facilities
Kathmandu Univ Med J (KUMJ), 10 (39), 48-51
DOI 10.3126/kumj.v10i3.8019, PubMed 23434962 -
Low dose hyper-radiosensitivity is eliminated during exposure to cycling hypoxia but returns after reoxygenation
Int J Radiat Biol, 88 (4), 311-9
DOI 10.3109/09553002.2012.646046, PubMed 22132723 -
Microenvironment-associated lymph node metastasis of human cervical carcinoma xenografts
Acta Oncol, 51 (4), 465-72
DOI 10.3109/0284186X.2011.636751, PubMed 22292610 -
pO₂ fluctuation pattern and cycling hypoxia in human cervical carcinoma and melanoma xenografts
Int J Radiat Oncol Biol Phys, 83 (4), 1317-23
DOI 10.1016/j.ijrobp.2011.09.037, PubMed 22270159 -
In vivo monitoring of liposomal release in tumours following ultrasound stimulation
Eur J Pharm Biopharm, 84 (3), 526-31
DOI 10.1016/j.ejpb.2012.12.007, PubMed 23274944 -
Cellular uptake of DNA-chitosan nanoparticles: the role of clathrin- and caveolae-mediated pathways
Int J Biol Macromol, 51 (5), 1043-51
DOI 10.1016/j.ijbiomac.2012.08.016, PubMed 22947453 -
A novel application of dorsal window chambers: repetitive imaging of tumor-associated lymphatics
Microvasc Res, 83 (3), 360-5
DOI 10.1016/j.mvr.2012.02.003, PubMed 22342351 -
Sunitinib treatment does not improve blood supply but induces hypoxia in human melanoma xenografts
BMC Cancer, 12, 388
DOI 10.1186/1471-2407-12-388, PubMed 22947392 -
Tumors exposed to acute cyclic hypoxia show increased vessel density and delayed blood supply
Microvasc Res, 85, 10-5
DOI 10.1016/j.mvr.2012.11.002, PubMed 23154277 -
Assessment of liposome biodistribution by non-invasive optical imaging: a feasibility study in tumour-bearing mice
J Nanosci Nanotechnol, 12 (3), 2912-8
DOI 10.1166/jnn.2012.5852, PubMed 22755141 -
Hypoxia-induced gene expression in chemoradioresistant cervical cancer revealed by dynamic contrast-enhanced MRI
Cancer Res, 72 (20), 5285-95
DOI 10.1158/0008-5472.CAN-12-1085, PubMed 22890239 -
Fractionated therapy of HER2-expressing breast and ovarian cancer xenografts in mice with targeted alpha emitting 227Th-DOTA-p-benzyl-trastuzumab
PLoS One, 7 (8), e42345
DOI 10.1371/journal.pone.0042345, PubMed 22879947 -
Preclinical evaluation of Gd-DTPA and gadomelitol as contrast agents in DCE-MRI of cervical carcinoma interstitial fluid pressure
BMC Cancer, 12, 544
DOI 10.1186/1471-2407-12-544, PubMed 23173554 -
Interstitial fluid pressure and associated lymph node metastasis revealed in tumors by dynamic contrast-enhanced MRI
Cancer Res, 72 (19), 4899-908
DOI 10.1158/0008-5472.CAN-12-0903, PubMed 23027087 -
Assessment of the interstitial fluid pressure of tumors by dynamic contrast-enhanced magnetic resonance imaging with contrast agents of different molecular weights
Acta Oncol, 52 (3), 627-35
DOI 10.3109/0284186X.2012.737931, PubMed 23126523 -
Reply to "Vitamin D supplementation did not prevent influenza-like illness as diagnosed retrospectively by questionnaires in subjects participating in randomized clinical trials"
Scand J Infect Dis, 44 (9), 712-3
DOI 10.3109/00365548.2012.658580, PubMed 22385298 -
Beneficial effects of UV radiation other than via vitamin D production
Dermatoendocrinol, 4 (2), 109-17
DOI 10.4161/derm.20013, PubMed 22928066 -
Transcriptional responses in irradiated and bystander fibroblasts after low dose α-particle radiation
Int J Radiat Biol, 88 (10), 713-9
DOI 10.3109/09553002.2012.704657, PubMed 22765265 -
The role of serotonin and p53 status in the radiation-induced bystander effect
Int J Radiat Biol, 88 (10), 773-6
DOI 10.3109/09553002.2012.711919, PubMed 22803606 -
Direct measurement of the interaction force between immunostimulatory CpG-DNA and TLR9 fusion protein
J Mol Recognit, 25 (2), 74-81
DOI 10.1002/jmr.2156, PubMed 22290768 -
Superficial-spreading and nodular melanomas in Norway: a comparison by body site distribution and latitude gradients
Melanoma Res, 22 (6), 460-5
DOI 10.1097/CMR.0b013e3283599cc3, PubMed 23010822 -
Blebbistatin, a myosin inhibitor, is phototoxic to human cancer cells under exposure to blue light
Biochim Biophys Acta, 1820 (7), 870-7
DOI 10.1016/j.bbagen.2012.04.003, PubMed 22507270 -
VITAMIN D AN ANTIMICROBIAL WEAPON AGAINST ACUTE RESPIRATORY TRACT INFECTIONS. A SYSTEMATIC REVIEW (2006-MARCH 2011)
Farmacia, 60 (2), 159-167 -
A laboratory inter-comparison of the importance of serum serotonin levels in the measurement of a range of radiation-induced bystander effects: overview of study and results presentation
Int J Radiat Biol, 88 (10), 763-9
DOI 10.3109/09553002.2012.715795, PubMed 22891994 -
Quantitative analysis of diffusion-weighted magnetic resonance imaging in malignant breast lesions using different b value combinations
Eur Radiol, 23 (4), 1027-33
DOI 10.1007/s00330-012-2687-8, PubMed 23111816 -
Dynamic contrast-enhanced magnetic resonance imaging of the metastatic potential of melanoma xenografts
Int J Radiat Oncol Biol Phys, 83 (1), e121-7
DOI 10.1016/j.ijrobp.2011.12.019, PubMed 22381901 -
Vitamin D status in healthy Romanian caregivers and risk of respiratory infections
Public Health Nutr, 15 (11), 2157-62
DOI 10.1017/S1368980012000158, PubMed 22414776 -
Vascular responses to radiotherapy and androgen-deprivation therapy in experimental prostate cancer
Radiat Oncol, 7, 75
DOI 10.1186/1748-717X-7-75, PubMed 22621752 -
Strongly amphiphilic photosensitizers are not substrates of the cancer stem cell marker ABCG2 and provides specific and efficient light-triggered drug delivery of an EGFR-targeted cytotoxic drug
J Control Release, 159 (2), 197-203
DOI 10.1016/j.jconrel.2012.02.003, PubMed 22349185 -
High interstitial fluid pressure is associated with tumor-line specific vascular abnormalities in human melanoma xenografts
PLoS One, 7 (6), e40006
DOI 10.1371/journal.pone.0040006, PubMed 22768196 -
Tumor-line specific causes of intertumor heterogeneity in blood supply in human melanoma xenografts
Microvasc Res, 85, 16-23
DOI 10.1016/j.mvr.2012.11.001, PubMed 23149341 -
Vascular abnormalities associated with acute hypoxia in human melanoma xenografts
Radiother Oncol, 105 (1), 72-8
DOI 10.1016/j.radonc.2012.08.018, PubMed 23022175 -
Dynamics of signaling, cytoskeleton and cell cycle regulation proteins in glioblastoma cells after sub-lethal photodynamic treatment: antibody microarray study
Biochim Biophys Acta, 1820 (7), 795-803
DOI 10.1016/j.bbagen.2012.03.008, PubMed 22484521 -
Photophysical and photobiological properties of a sulfonated chlorin photosensitiser TPCS(2a) for photochemical internalisation (PCI)
Photochem Photobiol Sci, 12 (3), 519-26
DOI 10.1039/c2pp25328c, PubMed 23232550 -
Dynamic contrast-enhanced magnetic resonance imaging of the metastatic potential of tumors: a preclinical study of cervical carcinoma and melanoma xenografts
Acta Oncol, 52 (3), 604-11
DOI 10.3109/0284186X.2012.689851, PubMed 22671573
Publications 2011
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Experimental α-particle radioimmunotherapy of breast cancer using 227Th-labeled p-benzyl-DOTA-trastuzumab
EJNMMI Res, 1 (1), 18
DOI 10.1186/2191-219X-1-18, PubMed 22214432 -
Photodynamic therapy of cancer: an update
CA Cancer J Clin, 61 (4), 250-81
DOI 10.3322/caac.20114, PubMed 21617154
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Dynamic contrast-enhanced MRI of cervical cancers: temporal percentile screening of contrast enhancement identifies parameters for prediction of chemoradioresistance
Int J Radiat Oncol Biol Phys, 82 (3), e485-92
DOI 10.1016/j.ijrobp.2011.05.050, PubMed 22014954 -
Pharmacokinetic analysis and k-means clustering of DCEMR images for radiotherapy outcome prediction of advanced cervical cancers
Acta Oncol, 50 (6), 859-65
DOI 10.3109/0284186X.2011.578586, PubMed 21767185 -
Insulin induces fatty acid desaturase expression in human monocytes
Scand J Clin Lab Invest, 71 (4), 330-9
DOI 10.3109/00365513.2011.566350, PubMed 21413848 -
Drug delivery technologies and immunological aspects of photodynamic therapy
Photochem Photobiol Sci, 10 (5), 647-8
DOI 10.1039/c1pp90010b, PubMed 21487635 -
Disulfonated tetraphenyl chlorin (TPCS2a), a novel photosensitizer developed for clinical utilization of photochemical internalization
Photochem Photobiol Sci, 10 (10), 1637-51
DOI 10.1039/c1pp05128h, PubMed 21773635 -
Weighted lasso with data integration
Stat Appl Genet Mol Biol, 10 (1)
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Carbon dots as antioxidants and prooxidants
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Toxicity and relative biological effectiveness of alpha emitting radioimmunoconjugates
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Dosimetry of a 238Pu-based alpha-particle irradiator and its biological application in a study of the bystander effect
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PubMed 21737630 -
Dynamic contrast-enhanced-MRI of tumor hypoxia
Magn Reson Med, 67 (2), 519-30
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Sonosensitive dioleoylphosphatidylethanolamine-containing liposomes with prolonged blood circulation time of doxorubicin
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Entrapment in phospholipid vesicles quenches photoactivity of quantum dots
Int J Nanomedicine, 6, 1875-88
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[A man in his 50's with hypotension and hyponatremia]
Tidsskr Nor Laegeforen, 131 (20), 2009-11
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Vitamin D levels in Norway may be inadequate to reduce risk of breast cancer
Int J Cancer, 128 (9), 2249-50
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Interstitial fluid pressure and vascularity of intradermal and intramuscular human tumor xenografts
Int J Radiat Oncol Biol Phys, 80 (1), 258-64
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Assessment of tumor hypoxia and interstitial fluid pressure by gadomelitol-based dynamic contrast-enhanced magnetic resonance imaging
Radiother Oncol, 101 (1), 217-22
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Differentiation between hypoxic and non-hypoxic experimental tumors by dynamic contrast-enhanced magnetic resonance imaging
Radiother Oncol, 98 (3), 360-4
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Ultrasound enhanced antitumor activity of liposomal doxorubicin in mice
J Drug Target, 19 (8), 701-8
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Liposomal doxorubicin improves radiotherapy response in hypoxic prostate cancer xenografts
Radiat Oncol, 6, 135
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Phosphorylation of EGFR measured with in situ proximity ligation assay: relationship to EGFR protein level and gene dosage in cervical cancer
Radiother Oncol, 101 (1), 152-7
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Membranous expression of ectodomain isoforms of the epidermal growth factor receptor predicts outcome after chemoradiotherapy of lymph node-negative cervical cancer
Clin Cancer Res, 17 (16), 5501-12
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Treatment of HER2-expressing breast cancer and ovarian cancer cells with alpha particle-emitting 227Th-trastuzumab
Int J Radiat Oncol Biol Phys, 79 (2), 563-70
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Bone morphogenetic proteins inhibit CD40L/IL-21-induced Ig production in human B cells: differential effects of BMP-6 and BMP-7
Eur J Immunol, 41 (11), 3135-45
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The future of medical diagnostics: review paper
Head Neck Oncol, 3, 38
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Dose evaluation and risk estimation for secondary cancer in contralateral breast and a study of correlation between thorax shape and dose to organs at risk following tangentially breast irradiation during deep inspiration breath-hold and free breathing
Acta Oncol, 50 (4), 563-8
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Side population cells in highly enriched CD34-positive cells from peripheral blood progenitor cells identify an immature subtype of hematopoietic progenitor cells but do not predict time to engraftment in patients treated with high-dose therapy
Eur J Haematol, 87 (6), 494-502
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Solar radiation and human health
Rep. Prog. Phys., 74 (6), 066701
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Malignant melanomas on head/neck and foot: differences in time and latitudinal trends in Norway
J Eur Acad Dermatol Venereol, 26 (7), 821-7
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[UV-A radiation and melanomas]
Tidsskr Nor Laegeforen, 131 (4), 333; author reply 333-4
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SET8 is degraded via PCNA-coupled CRL4(CDT2) ubiquitylation in S phase and after UV irradiation
J Cell Biol, 192 (1), 43-54
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Respiratory motion prediction: A fuzzy logic approach
FRONT ARTIF INTEL AP, 227, 108-121
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Genome-wide microarray analysis of human fibroblasts in response to γ radiation and the radiation-induced bystander effect
Radiat Res, 177 (1), 35-43
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Cell-cycle analysis of fission yeast cells by flow cytometry
PLoS One, 6 (2), e17175
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Protein phosphatase 1 regulators in DNA damage signaling
Cell Cycle, 10 (9), 1356-62
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Three independent mechanisms for arrest in G2 after ionizing radiation
Cell Cycle, 10 (5), 819-29
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Prostate cancer cell lines under hypoxia exhibit greater stem-like properties
PLoS One, 6 (12), e29170 (Retracted)
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A genetic screen identifies BRCA2 and PALB2 as key regulators of G2 checkpoint maintenance
EMBO Rep, 12 (7), 705-12
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Comparison of the time and latitude trends of melanoma incidence in anorectal region and perianal skin with those of cutaneous malignant melanoma in Norway
J Eur Acad Dermatol Venereol, 25 (12), 1444-9
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Bioimpedance for pain monitoring during cutaneous photodynamic therapy: Preliminary study
Photodiagnosis Photodyn Ther, 8 (4), 307-13
DOI 10.1016/j.pdpdt.2011.06.001, PubMed 22122917 -
Vitamin D, sun, sunbeds and health
Public Health Nutr, 15 (4), 711-5
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UVA, UVB and incidence of cutaneous malignant melanoma in Norway and Sweden
Photochem Photobiol Sci, 11 (1), 191-8
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Immediate pigment darkening: its evolutionary roles may include protection against folate photosensitization
FASEB J, 26 (3), 971-5
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Fluorescence photobleaching of ALA and ALA-heptyl ester induced protoporphyrin IX during photodynamic therapy of normal hairless mouse skin: a comparison of two light sources and different illumination schemes
J Environ Pathol Toxicol Oncol, 30 (3), 235-40
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Epigallocatechin gallate-loaded polysaccharide nanoparticles for prostate cancer chemoprevention
Nanomedicine (Lond), 6 (1), 79-87
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Early prediction of response to radiotherapy and androgen-deprivation therapy in prostate cancer by repeated functional MRI: a preclinical study
Radiat Oncol, 6, 65
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Quantum dots affect expression of CD133 surface antigen in melanoma cells
Int J Nanomedicine, 6, 2437-44
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Safeguarding genome integrity: the checkpoint kinases ATR, CHK1 and WEE1 restrain CDK activity during normal DNA replication
Nucleic Acids Res, 40 (2), 477-86
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The amount of DNA damage needed to activate the radiation-induced G2 checkpoint varies between single cells
Radiother Oncol, 101 (1), 24-7
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At the frontiers of surgery: review
Head Neck Oncol, 3 (1), 7
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Photochemical internalization of tumor-targeted protein toxins
Lasers Surg Med, 43 (7), 721-33
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Assessment of tumor radioresponsiveness and metastatic potential by dynamic contrast-enhanced magnetic resonance imaging
Int J Radiat Oncol Biol Phys, 81 (1), 255-61
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Assessment of hypoxia and radiation response in intramuscular experimental tumors by dynamic contrast-enhanced magnetic resonance imaging
Radiother Oncol, 102 (3), 429-35
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Publications 2010
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High-throughput siRNA screens using γH2AX as marker uncover key regulators of genome integrity in mammalian cells
Cell Cycle, 9 (12), 2257-8
DOI 10.4161/cc.9.12.12017, PubMed 20699633 -
Regulators of cyclin-dependent kinases are crucial for maintaining genome integrity in S phase
J Cell Biol, 188 (5), 629-38
DOI 10.1083/jcb.200905059, PubMed 20194642 -
Photochemical internalization: a new tool for gene and oligonucleotide delivery
Top Curr Chem, 296, 251-81
DOI 10.1007/128_2010_63, PubMed 21504105 -
Photochemical internalization (PCI): a technology for drug delivery
Methods Mol Biol, 635, 133-45
DOI 10.1007/978-1-60761-697-9_10, PubMed 20552345 -
Latitude gradient for melanoma incidence by anatomic site and gender in Norway 1966-2007
J Photochem Photobiol B, 101 (2), 174-8
DOI 10.1016/j.jphotobiol.2010.04.002, PubMed 20430639 -
Influence of narrowband UVB phototherapy on vitamin D and folate status
Exp Dermatol, 19 (8), e67-72
DOI 10.1111/j.1600-0625.2009.00987.x, PubMed 19849714 -
Assessment of long-term radiotoxicity after treatment with the low-dose-rate alpha-particle-emitting radioimmunoconjugate (227)Th-rituximab
Eur J Nucl Med Mol Imaging, 37 (1), 93-102
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CT density in lung cancer patients after radiotherapy sensitized by metoclopramide. A subgroup analysis of a randomized trial
Strahlenther Onkol, 186 (3), 163-8
DOI 10.1007/s00066-010-2040-6, PubMed 20165821 -
Magnetic resonance imaging of tumor necrosis
Acta Oncol, 50 (3), 427-34
DOI 10.3109/0284186X.2010.526633, PubMed 20950229 -
Dynamic contrast-enhanced magnetic resonance imaging of human cervical carcinoma xenografts: pharmacokinetic analysis and correlation to tumor histomorphology
Radiother Oncol, 97 (2), 217-24
DOI 10.1016/j.radonc.2010.06.011, PubMed 20656365 -
Cytotoxicity and Phototoxicity of Red Fluorescent Nontargeted Quantum Dots
IEEE J. Sel. Top. Quantum Electron., 16 (4), 997-1003
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Increased expression of bcl11b leads to chemoresistance accompanied by G1 accumulation
PLoS One, 5 (9)
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Review Article: Health benefit of increased serum 25(OH)D levels from oral intake and ultraviolet-B irradiance in the Nordic countries
Scand J Public Health, 39 (1), 70-8
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Similarities in solar ultraviolet irradiance and other environmental factors may explain much of the family link between uveal melanoma and other cancers
Fam Cancer, 9 (4), 659-60; discussion 661-2
DOI 10.1007/s10689-010-9374-1, PubMed 20711817 -
Indoor tanning and risk of melanoma: a case-control study in a highly exposed population - letter
Cancer Epidemiol Biomarkers Prev, 19 (10), 2685; author reply 2685-6
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Optimal use of AEC in CT: a literature review
Radiol Technol, 81 (4), 309-17
PubMed 20207787 -
Interstitial fluid pressure of tumors as a function of parameters derived by dynamic contrast-enhanced magnetic resonance imaging: Response to letter by Farace and Boschi
Radiother. Oncol., 94 (3), 385-386
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Quantitative assessment of hypoxia in melanoma xenografts by dynamic contrast-enhanced magnetic resonance imaging: intradermal versus intramuscular tumors
Radiother Oncol, 97 (2), 233-8
DOI 10.1016/j.radonc.2010.09.005, PubMed 20934767 -
Enhancement characteristics of lymphomatous lymph nodes of the neck
Acta Radiol, 51 (5), 555-62
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[Photochemical internalisation (PCI): a further development of photodynamic therapy for the treatment of skin cancer]
Praxis (Bern 1994), 99 (23), 1423-8
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Reduction of cutaneous photosensitivity by application of ointment containing ferrous or cobaltous ions concomitant with the use of topical protoporphyrin IX precursors
Photodiagnosis Photodyn Ther, 7 (3), 152-7
DOI 10.1016/j.pdpdt.2010.06.003, PubMed 20728838 -
Reflectance spectroscopy and fluorescein angiography applied to assess photodynamic response in healthy mouse skin treated with topical hexylaminolevulinate
Photodiagnosis Photodyn Ther, 7 (4), 239-45
DOI 10.1016/j.pdpdt.2010.07.001, PubMed 21112546 -
Application of 5-aminolevulinic acid and its derivatives for photodynamic therapy in vitro and in vivo
Methods Mol Biol, 635, 97-106
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The seasonality of pandemic and non-pandemic influenzas: the roles of solar radiation and vitamin D
Int J Infect Dis, 14 (12), e1099-105
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Pilot study of folate status in healthy volunteers and in patients with psoriasis before and after UV exposure
J Photochem Photobiol B, 101 (2), 111-6
DOI 10.1016/j.jphotobiol.2010.01.013, PubMed 20207157 -
Metabolic-targeted therapy with dichloroacetate (DCA): a novel treatment strategy to improve the outcome of photodynamic therapy
Photochem Photobiol Sci, 10 (1), 25-8
DOI 10.1039/c0pp00193g, PubMed 20978658 -
Obesity and increased risk of cancer: does decrease of serum 25-hydroxyvitamin D level with increasing body mass index explain some of the association?
Mol Nutr Food Res, 54 (8), 1127-33
DOI 10.1002/mnfr.200900512, PubMed 20512788 -
Vitamin D status in Norwegian children and adolescents with excess body weight
Pediatr Diabetes, 12 (2), 120-6
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Serum 25-hydroxyvitamin D is a predictor of serum 1,25-dihydroxyvitamin D in overweight and obese patients
J Nutr, 141 (1), 112-7
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The protein phosphatase 1 regulator PNUTS is a new component of the DNA damage response
EMBO Rep, 11 (11), 868-75
DOI 10.1038/embor.2010.134, PubMed 20890310 -
Improved image quality of low-dose thoracic CT examinations with a new postprocessing software
J Appl Clin Med Phys, 11 (3), 3242
DOI 10.1120/jacmp.v11i3.3242, PubMed 20717095 -
Microneedle pre-treatment of human skin improves 5-aminolevulininc acid (ALA)- and 5-aminolevulinic acid methyl ester (MAL)-induced PpIX production for topical photodynamic therapy without increase in pain or erythema
Pharm Res, 27 (10), 2213-20
DOI 10.1007/s11095-010-0227-2, PubMed 20676735 -
Time trends and latitude dependence of uveal and cutaneous malignant melanoma induced by solar radiation
Dermatoendocrinol, 2 (1), 3-8
DOI 10.4161/derm.2.1.11745, PubMed 21547141 -
Solar radiation and human health
J Photochem Photobiol B, 101 (2), 109-10
DOI 10.1016/j.jphotobiol.2010.08.004, PubMed 20833325 -
Where the sun does not shine: is sunshine protective against melanoma of the vulva?
J Photochem Photobiol B, 101 (2), 179-83
DOI 10.1016/j.jphotobiol.2010.03.003, PubMed 20359907 -
Novel patch-based systems for the localised delivery of ALA-esters
J Photochem Photobiol B, 101 (1), 59-69
DOI 10.1016/j.jphotobiol.2010.06.012, PubMed 20634088 -
Influence of penetration enhancers on topical delivery of 5-aminolevulinic acid from bioadhesive patches
J Pharm Pharmacol, 62 (6), 685-95
DOI 10.1211/jpp.62.06.0004, PubMed 20636855 -
Hexyl aminolaevulinate is a more effective topical photosensitiser precursor than methyl aminolaevulinate and 5-aminolaevulinic acids when applied in equimolar doses
J Pharm Sci, 99 (8), 3486-98
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Diffusion-weighted magnetic resonance imaging for pretreatment prediction and monitoring of treatment response of patients with locally advanced breast cancer undergoing neoadjuvant chemotherapy
Acta Oncol, 49 (3), 354-60
DOI 10.3109/02841861003610184, PubMed 20397769 -
CSPP is a ciliary protein interacting with Nephrocystin 8 and required for cilia formation
Mol Biol Cell, 21 (15), 2555-67
DOI 10.1091/mbc.e09-06-0503, PubMed 20519441 -
p53-dependent G(1) arrest in 1st or 2nd cell cycle may protect human cancer cells from cell death after treatment with ionizing radiation and Chk1 inhibitors
Cell Prolif, 43 (4), 365-71
DOI 10.1111/j.1365-2184.2010.00685.x, PubMed 20590661 -
Characterization of cancer stem cells and their response to CdTe quantum dots
Med Phys Balt Stat, 8, 71-76
PublikaID 41 -
Vorinostat, a histone deacetylase inhibitor, combined with pelvic palliative radiotherapy for gastrointestinal carcinoma: the Pelvic Radiation and Vorinostat (PRAVO) phase 1 study
Lancet Oncol, 11 (5), 459-64
DOI 10.1016/S1470-2045(10)70058-9, PubMed 20378407 -
Assessing autophagy in the context of photodynamic therapy
Autophagy, 6 (1), 7-18
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Tumors exposed to acute cyclic hypoxic stress show enhanced angiogenesis, perfusion and metastatic dissemination
Int J Cancer, 127 (7), 1535-46
DOI 10.1002/ijc.25176, PubMed 20091868 -
Metastasis in melanoma xenografts is associated with tumor microvascular density rather than extent of hypoxia
Neoplasia, 12 (11), 889-98
DOI 10.1593/neo.10712, PubMed 21076614 -
Associations between radiocurability and interstitial fluid pressure in human tumor xenografts without hypoxic tissue
Clin Cancer Res, 16 (3), 936-45
DOI 10.1158/1078-0432.CCR-09-2718, PubMed 20103667 -
Feasibility of contrast-enhanced cone-beam CT for target localization and treatment monitoring
Radiother Oncol, 97 (3), 521-4
DOI 10.1016/j.radonc.2010.07.006, PubMed 20667609 -
Preclinical dynamic 18F-FDG PET - tumor characterization and radiotherapy response assessment by kinetic compartment analysis
Acta Oncol, 49 (7), 914-21
DOI 10.3109/0284186X.2010.498831, PubMed 20831478 -
Longitudinal magnetic resonance imaging-based assessment of vascular changes and radiation response in androgen-sensitive prostate carcinoma xenografts under androgen-exposed and androgen-deprived conditions
Neoplasia, 12 (10), 818-25
DOI 10.1593/neo.10484, PubMed 20927320 -
Photochemical internalization provides time- and space-controlled endolysosomal escape of therapeutic molecules
J Control Release, 148 (1), 2-12
DOI 10.1016/j.jconrel.2010.06.008, PubMed 20600406 -
Development of hypoxia in a preclinical model of tumor micrometastases
Int J Radiat Oncol Biol Phys, 76 (3), 879-88
DOI 10.1016/j.ijrobp.2009.09.045, PubMed 20159362 -
Adapting biological feedback in radiotherapy
Semin Radiat Oncol, 20 (2), 138-46
DOI 10.1016/j.semradonc.2009.11.008, PubMed 20219552 -
Predicted risk of radiation-induced cancers after involved field and involved node radiotherapy with or without intensity modulation for early-stage hodgkin lymphoma in female patients
Int J Radiat Oncol Biol Phys, 81 (2), 490-7
DOI 10.1016/j.ijrobp.2010.05.035, PubMed 20800383 -
Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer
Sci Transl Med, 2 (62), 62ra93
DOI 10.1126/scitranslmed.3001451, PubMed 21160078
Publications 2009
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Cancer treatment by radiotherapy in Western Nepal: a hospital-based study
Asian Pac J Cancer Prev, 10 (2), 205-8
PubMed 19537884 -
Checkpoint regulation of DNA replication
Methods Mol Biol, 521, 55-70
DOI 10.1007/978-1-60327-815-7_4, PubMed 19563101 -
Sun and sun beds: inducers of vitamin D and skin cancer
Anticancer Res, 29 (9), 3495-500
PubMed 19667143 -
Calcitriol treatment improves methyl aminolaevulinate-based photodynamic therapy in human squamous cell carcinoma A431 cells
Br J Dermatol, 161 (2), 413-8
DOI 10.1111/j.1365-2133.2009.09180.x, PubMed 19438460 -
In vitro cytotoxicity of low-dose-rate radioimmunotherapy by the alpha-emitting radioimmunoconjugate Thorium-227-DOTA-rituximab
Int J Radiat Oncol Biol Phys, 75 (3), 886-95
DOI 10.1016/j.ijrobp.2009.04.062, PubMed 19679402 -
Influence of formulation factors on PpIX production and photodynamic action of novel ALA-loaded microparticles
Biopharm Drug Dispos, 30 (2), 55-70
DOI 10.1002/bdd.645, PubMed 19226650 -
The elimination of low-dose hyper-radiosensitivity by transfer of irradiated-cell conditioned medium depends on dose rate
Radiat Res, 171 (1), 22-32
DOI 10.1667/RR1143.1, PubMed 19138044 -
Dynamic contrast-enhanced magnetic resonance imaging of tumors: preclinical validation of parametric images
Radiat Res, 172 (3), 339-47
DOI 10.1667/RR1787.1, PubMed 19708783 -
Assessment of hypoxia in human cervical carcinoma xenografts by dynamic contrast-enhanced magnetic resonance imaging
Int J Radiat Oncol Biol Phys, 73 (3), 838-45
DOI 10.1016/j.ijrobp.2008.10.062, PubMed 19215820 -
Human cervical carcinoma xenograft models for studies of the physiological microenvironment of tumors
J Cancer Res Clin Oncol, 135 (9), 1177-84
DOI 10.1007/s00432-009-0558-8, PubMed 19214568 -
Open letter to IARC Director Christopher P. Wild-Re: IARC Working Group Report 5: Vitamin D and Cancer
Dermatoendocrinol, 1 (2), 119-20
DOI 10.4161/derm.1.2.8512, PubMed 20224695 -
Blood supply in melanoma xenografts is governed by the morphology of the supplying arteries
Neoplasia, 11 (3), 277-85
DOI 10.1593/neo.81400, PubMed 19242609 -
Generation of singlet oxygen and other radical species by quantum dot and carbon dot nanosensitizers
PROC SPIE, 7380, 738072
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Estimated benefit of increased vitamin D status in reducing the economic burden of disease in western Europe
Prog Biophys Mol Biol, 99 (2-3), 104-13
DOI 10.1016/j.pbiomolbio.2009.02.003, PubMed 19268496 -
Late effects after radiotherapy for locally advanced cervical cancer: comparison of two brachytherapy schedules and effect of dose delivered weekly
Int J Radiat Oncol Biol Phys, 76 (3), 713-8
DOI 10.1016/j.ijrobp.2009.02.024, PubMed 19427739 -
Parathyroid hormone, but not vitamin D, is associated with the metabolic syndrome in morbidly obese women and men: a cross-sectional study
Cardiovasc Diabetol, 8, 7
DOI 10.1186/1475-2840-8-7, PubMed 19187564 -
Expression of 14-3-3sigma in cervical squamous cell carcinomas: relationship with clinical outcome
Oncol Rep, 22 (1), 11-5
DOI 10.3892/or_00000399, PubMed 19513498 -
A planning comparison of dose patterns in organs at risk and predicted risk for radiation induced malignancy in the contralateral breast following radiation therapy of primary breast using conventional, IMRT and volumetric modulated arc treatment techniques
Acta Oncol, 48 (4), 495-503
DOI 10.1080/02841860802657227, PubMed 19169915 -
Chlorin e6-based photosensitizers for photodynamic therapy and photodiagnosis
Photodiagnosis Photodyn. Ther., 6 (2), 94-96
DOI 10.1016/j.pdpdt.2009.06.001 -
Clearance of protoporphyrin IX induced by 5-aminolevulinic acid from WiDr human colon carcinoma cells
PROC SPIE, 7380, 73802Q
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[Sun, vitamin D and health]
Tidsskr Nor Laegeforen, 129 (19), 2019
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Development of different human skin colors: a review highlighting photobiological and photobiophysical aspects
J Photochem Photobiol B, 96 (2), 93-100
DOI 10.1016/j.jphotobiol.2009.04.009, PubMed 19481954 -
5-Methyltetrahydrofolate can be photodegraded by endogenous photosensitizers
Free Radic Biol Med, 47 (8), 1199-204
DOI 10.1016/j.freeradbiomed.2009.07.030, PubMed 19647791 -
Artificial neural networks for prediction of response to chemoradiation in HT29 xenografts
Int J Radiat Oncol Biol Phys, 75 (2), 506-11
DOI 10.1016/j.ijrobp.2009.05.036, PubMed 19735875 -
Photodynamic therapy with 5-aminolevulinic acid and diamino acid derivatives of protoporphyrin IX reduces papillomas in mice without eliminating transformation into squamous cell carcinoma of the skin
Int J Cancer, 125 (7), 1721-7
DOI 10.1002/ijc.24488, PubMed 19521986 -
The dependency of vitamin D status on body mass index, gender, age and season
Anticancer Res, 29 (9), 3713-20
DOI 10.14341/2071-8713-4886, PubMed 19667169 -
Gene dosage, expression, and ontology analysis identifies driver genes in the carcinogenesis and chemoradioresistance of cervical cancer
PLoS Genet, 5 (11), e1000719
DOI 10.1371/journal.pgen.1000719, PubMed 19911042 -
Topical aminolaevulinic acid- and aminolaevulinic acid methyl ester-based photodynamic therapy with red and violet light: influence of wavelength on pain and erythema
Br J Dermatol, 161 (5), 1173-9
DOI 10.1111/j.1365-2133.2009.09437.x, PubMed 19785604 -
A pilot study comparing the pain sensations during PpIX build-up and clearance phases
PROC SPIE, 7380, 73802Y
DOI 10.1117/12.822949 -
Solar radiation, vitamin D and cancer incidence and mortality in Norway
Anticancer Res, 29 (9), 3501-9
PubMed 19667144 -
Influenza, solar radiation and vitamin D
Dermatoendocrinol, 1 (6), 307-9
DOI 10.4161/derm.1.6.11357, PubMed 21572876 -
Sunbeds as vitamin D sources
Photochem Photobiol, 85 (6), 1474-9
DOI 10.1111/j.1751-1097.2009.00607.x, PubMed 19788534 -
Seasonal variation of 1,25-dihydroxyvitamin D and its association with body mass index and age
J Steroid Biochem Mol Biol, 113 (3-5), 217-21
DOI 10.1016/j.jsbmb.2009.01.001, PubMed 19444938 -
Photosensitizing properties of chlorins in solution and in membrane-mimicking systems
Photochem Photobiol Sci, 8 (6), 778-87
DOI 10.1039/b822269j, PubMed 19492105 -
The vitamin D status among Tibetans
Photochem Photobiol, 85 (4), 1028-31
DOI 10.1111/j.1751-1097.2009.00552.x, PubMed 19508646 -
Photochemical internalization of bleomycin before external-beam radiotherapy improves locoregional control in a human sarcoma model
Int J Radiat Oncol Biol Phys, 75 (3), 878-85
DOI 10.1016/j.ijrobp.2009.04.039, PubMed 19665318 -
Photochemical internalization as an adjunct to marginal surgery in a human sarcoma model
Photochem Photobiol Sci, 8 (6), 758-62
DOI 10.1039/b821129a, PubMed 19492102 -
Photochemical internalization (PCI) in cancer therapy: from bench towards bedside medicine
J Photochem Photobiol B, 96 (2), 83-92
DOI 10.1016/j.jphotobiol.2009.04.012, PubMed 19467605 -
Nano-medicine in Cancer Therapy
IFMBE PROC, 25 (13), 222 -
A comparison of 5-aminolaevulinic acid- and its heptyl ester: dark cytotoxicity and protoporphyrin IX synthesis in human adenocarcinoma WiDr cells and in athymic nude mice healthy skin
Exp Dermatol, 18 (11), 985-7
DOI 10.1111/j.1600-0625.2009.00863.x, PubMed 19469901 -
Radiocurability is associated with interstitial fluid pressure in human tumor xenografts
Neoplasia, 11 (11), 1243-51
DOI 10.1593/neo.91152, PubMed 19881960 -
Marine n-3 fatty acids promote size reduction of visceral adipose depots, without altering body weight and composition, in male Wistar rats fed a high-fat diet
Br J Nutr, 102 (7), 995-1006
DOI 10.1017/S0007114509353210, PubMed 19397836 -
MR-guided simultaneous integrated boost in preoperative radiotherapy of locally advanced rectal cancer following neoadjuvant chemotherapy
Radiother Oncol, 93 (2), 279-84
DOI 10.1016/j.radonc.2009.08.046, PubMed 19800704 -
Multi-modality therapeutics with potent anti-tumor effects: photochemical internalization enhances delivery of the fusion toxin scFvMEL/rGel
PLoS One, 4 (8), e6691
DOI 10.1371/journal.pone.0006691, PubMed 19690617 -
Strategies for biologic image-guided dose escalation: a review
Int J Radiat Oncol Biol Phys, 73 (3), 650-8
DOI 10.1016/j.ijrobp.2008.11.001, PubMed 19215819 -
DCEMRI of spontaneous canine tumors during fractionated radiotherapy: a pharmacokinetic analysis
Radiother Oncol, 93 (3), 618-24
DOI 10.1016/j.radonc.2009.08.012, PubMed 19747746 -
A (238)Pu irradiator for exposure of cultured cells with alpha-radiation: construction, calibration and dosimetry
Appl Radiat Isot, 67 (11), 1998-2002
DOI 10.1016/j.apradiso.2009.08.003, PubMed 19716308 -
Head & neck optical diagnostics: vision of the future of surgery
Head Neck Oncol, 1, 25
DOI 10.1186/1758-3284-1-25, PubMed 19594907 -
Dietary supplementation of tetradecylthioacetic acid increases feed intake but reduces body weight gain and adipose depot sizes in rats fed on high-fat diets
Diabetes Obes Metab, 11 (11), 1034-49
DOI 10.1111/j.1463-1326.2009.01092.x, PubMed 19740081 -
Photodynamic therapy targets the mTOR signaling network in vitro and in vivo
Mol Pharm, 6 (1), 255-64
DOI 10.1021/mp800156e, PubMed 19125612 -
Intracellular re-localisation by photochemical internalisation enhances the cytotoxic effect of gelonin--quantitative studies in normal rat liver
J Control Release, 142 (3), 347-53
DOI 10.1016/j.jconrel.2009.11.017, PubMed 19932724
Publications 2008
-
Limitations of dynamic contrast-enhanced MRI in monitoring radiation-induced changes in the fraction of radiobiologically hypoxic cells in human melanoma xenografts
J Magn Reson Imaging, 28 (5), 1209-18
DOI 10.1002/jmri.21602, PubMed 18972344 -
Photochemical enhancement of DNA delivery by EGF receptor targeted polyplexes
Methods Mol Biol, 434, 171-81
DOI 10.1007/978-1-60327-248-3_11, PubMed 18470645 -
Temporal heterogeneity in blood supply in human tumor xenografts
Neoplasia, 10 (7), 727-35
DOI 10.1593/neo.08388, PubMed 18592011 -
Relative biologic effects of low-dose-rate alpha-emitting 227Th-rituximab and beta-emitting 90Y-tiuexetan-ibritumomab versus external beam X-radiation
Int J Radiat Oncol Biol Phys, 72 (1), 186-92
DOI 10.1016/j.ijrobp.2008.05.029, PubMed 18722269 -
Overexpression of human OGG1 in mammalian cells decreases ultraviolet A induced mutagenesis
Cancer Lett, 267 (1), 18-25
DOI 10.1016/j.canlet.2008.03.002, PubMed 18406515 -
Targeted Alpha-Particle Therapy with Th-227-Labeled Antibodies
Curr. Radiopharm., 1 (3), 209-214
DOI 10.2174/1874471010801030209 -
Microneedle arrays permit enhanced intradermal delivery of a preformed photosensitizer
Photochem Photobiol, 85 (1), 195-204
DOI 10.1111/j.1751-1097.2008.00417.x, PubMed 18764907 -
Microneedle-mediated intradermal delivery of 5-aminolevulinic acid: potential for enhanced topical photodynamic therapy
J Control Release, 129 (3), 154-62
DOI 10.1016/j.jconrel.2008.05.002, PubMed 18556084 -
Assessment of fraction of hypoxic cells in human tumor xenografts with necrotic regions by dynamic contrast-enhanced MRI
Radiat Res, 169 (6), 689-99
DOI 10.1667/RR1311.1, PubMed 18494552 -
Indirect genomic effects on survival from gene expression data
Genome Biol, 9 (3), R58
DOI 10.1186/gb-2008-9-3-r58, PubMed 18358079 -
Tumor vascularity assessed by magnetic resonance imaging and intravital microscopy imaging
Neoplasia, 10 (4), 354-62
DOI 10.1593/neo.08162, PubMed 18392132 -
Dynamic contrast-enhanced magnetic resonance imaging of tumor interstitial fluid pressure
Radiother Oncol, 91 (1), 107-13
DOI 10.1016/j.radonc.2008.08.015, PubMed 18973959 -
Detection of different hypoxic cell subpopulations in human melanoma xenografts by pimonidazole immunohistochemistry
Radiat Res, 170 (5), 638-50
DOI 10.1667/RR1400.1, PubMed 18959463 -
The concept of advanced radiographic practice: An international perspective
Radiography, 14 1, E15-E19
DOI 10.1016/j.radi.2008.10.001 -
Human papillomavirus DNA and e6/e7 mRNA status in relation to survival of patients treated for cervical squamous cell carcinoma
Open Virol J, 2, 74-81
DOI 10.2174/1874357900802010074, PubMed 19440467 -
Estimated risk for secondary cancer in the contra-lateral breast following radiation therapy of breast cancer
Acta Oncol, 47 (3), 391-6
DOI 10.1080/02841860701846152, PubMed 18348001 -
Quantum dots and nanoparticles for photodynamic and radiation therapies of cancer
Adv Drug Deliv Rev, 60 (15), 1600-14
DOI 10.1016/j.addr.2008.08.004, PubMed 18840487 -
Generation of Nitrogen Oxide and Oxygen Radicals by Quantum Dots
J. Biomed. Nanotechnol., 4 (4), 450-456
DOI 10.1166/jbn.2008.008 -
Depth profile of protoporphyrin IX fluorescence in an amelanotic mouse melanoma model
Photochem Photobiol, 85 (3), 760-4
DOI 10.1111/j.1751-1097.2008.00496.x, PubMed 19140894 -
Changes in human skin after topical PDT with hexyl aminolevulinate
Photodiagnosis Photodyn Ther, 5 (3), 176-81
DOI 10.1016/j.pdpdt.2008.07.001, PubMed 19356652 -
Automatic segmentation and recognition of lungs and lesion from CT scans of thorax
Comput Med Imaging Graph, 33 (1), 72-82
DOI 10.1016/j.compmedimag.2008.10.009, PubMed 19059759 -
Immunotherapy: a way to improve the therapeutic outcome of photodynamic therapy?
Photochem Photobiol Sci, 7 (9), 1011-7
DOI 10.1039/b806710d, PubMed 18754046 -
Enhanced cytotoxicity of saporin by polyamidoamine dendrimer conjugation and photochemical internalization
J Biomed Mater Res A, 87 (1), 147-55
DOI 10.1002/jbm.a.31760, PubMed 18085655 -
Dynamic and structural aspects of PEGylated liposomes monitored by NMR
J Colloid Interface Sci, 325 (2), 485-93
DOI 10.1016/j.jcis.2008.05.051, PubMed 18589432 -
GeneCount: genome-wide calculation of absolute tumor DNA copy numbers from array comparative genomic hybridization data
Genome Biol, 9 (5), R86
DOI 10.1186/gb-2008-9-5-r86, PubMed 18500990 -
Reduction in dose from CT examinations of liver lesions with a new postprocessing filter: a ROC phantom study
Acta Radiol, 49 (3), 303-9
DOI 10.1080/02841850701793769, PubMed 18365819 -
Effect of (R)L-sulforaphane on 5-aminolevulinic acid-mediated photodynamic therapy
Transl Res, 152 (3), 128-33
DOI 10.1016/j.trsl.2008.07.004, PubMed 18774542 -
At what time should one go out in the sun?
Adv Exp Med Biol, 624, 86-8
DOI 10.1007/978-0-387-77574-6_7, PubMed 18348449 -
Ultraviolet radiation and malignant melanoma
Adv Exp Med Biol, 624, 104-16
DOI 10.1007/978-0-387-77574-6_9, PubMed 18348451 -
Addressing the health benefits and risks, involving vitamin D or skin cancer, of increased sun exposure
Proc Natl Acad Sci U S A, 105 (2), 668-73
DOI 10.1073/pnas.0710615105, PubMed 18180454 -
Retrieval of the physiological state of human skin from UV-Vis reflectance spectra - a feasibility study
J Photochem Photobiol B, 93 (1), 23-31
DOI 10.1016/j.jphotobiol.2008.06.010, PubMed 18682328 -
Photochemical internalization of bleomycin is superior to photodynamic therapy due to the therapeutic effect in the tumor periphery
Photochem Photobiol, 85 (3), 740-9
DOI 10.1111/j.1751-1097.2008.00477.x, PubMed 19076314 -
Validation of oligoarrays for quantitative exploration of the transcriptome
BMC Genomics, 9, 258
DOI 10.1186/1471-2164-9-258, PubMed 18513391 -
Lasers in medicine
Rep. Prog. Phys., 71 (5), 056701
DOI 10.1088/0034-4885/71/5/056701 -
Sun beds and cod liver oil as vitamin D sources
J Photochem Photobiol B, 91 (2-3), 125-31
DOI 10.1016/j.jphotobiol.2008.02.007, PubMed 18417354 -
Sun exposure and cancer survival in Norway: changes in the risk of death with season of diagnosis and latitude
Adv Exp Med Biol, 624, 43-54
DOI 10.1007/978-0-387-77574-6_4, PubMed 18348446 -
Teleradiology with satellite units - six years experience at the norwegian radium hospital
Stud Health Technol Inform, 134, 209-16
PubMed 18376048 -
Dynamic contrast enhanced magnetic resonance imaging of bladder cancer and implications for biological image-adapted radiotherapy
Acta Oncol, 47 (7), 1257-64
DOI 10.1080/02841860802244174, PubMed 18618299 -
Principal component analysis for the comparison of metabolic profiles from human rectal cancer biopsies and colorectal xenografts using high-resolution magic angle spinning 1H magnetic resonance spectroscopy
Mol Cancer, 7, 33
DOI 10.1186/1476-4598-7-33, PubMed 18439252 -
5-Methyltetrahydrofolate is photosensitive in the presence of riboflavin
Photochem Photobiol Sci, 7 (7), 814-8
DOI 10.1039/b718907a, PubMed 18597029 -
DCEMRI monitoring of canine tumors during fractionated radiotherapy
Acta Oncol, 47 (7), 1249-56
DOI 10.1080/02841860802244166, PubMed 18618342 -
Radiological and functional assessment of radiation-induced pulmonary damage following breast irradiation
Acta Oncol, 47 (2), 248-54
DOI 10.1080/02841860701630267, PubMed 18210300 -
Late regional density changes of the lung after radiotherapy for breast cancer
Radiother Oncol, 90 (1), 148-52
DOI 10.1016/j.radonc.2007.12.031, PubMed 18262670 -
Photodynamic therapy with an endocytically located photosensitizer cause a rapid activation of the mitogen-activated protein kinases extracellular signal-regulated kinase, p38, and c-Jun NH2 terminal kinase with opposing effects on cell survival
Mol Cancer Ther, 7 (6), 1740-50
DOI 10.1158/1535-7163.MCT-08-0020, PubMed 18566245 -
Photodynamic targeting of EGFR does not predict the treatment outcome in combination with the EGFR tyrosine kinase inhibitor Tyrphostin AG1478
Photochem Photobiol Sci, 7 (9), 1032-40
DOI 10.1039/b806209a, PubMed 18754049 -
Effect of oxygen concentration on photo-oxidation and photosensitizer bleaching in butter
Photochem Photobiol, 85 (3), 669-76
DOI 10.1111/j.1751-1097.2008.00492.x, PubMed 19140897
Publications 2007
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Assessment of extravascular extracellular space fraction in human melanoma xenografts by DCE-MRI and kinetic modeling
Magn Reson Imaging, 26 (2), 160-70
DOI 10.1016/j.mri.2007.06.003, PubMed 17692490 -
Photochemical internalization: a new tool for drug delivery
Curr Pharm Biotechnol, 8 (6), 362-72
DOI 10.2174/138920107783018354, PubMed 18289045 -
Fluctuations in tumor blood perfusion assessed by dynamic contrast-enhanced MRI
Magn Reson Med, 58 (3), 473-81
DOI 10.1002/mrm.21367, PubMed 17763357 -
Photodynamic therapy with di-l-arginine protoporphyrinate on WiDr human colon adenocarcinoma xenografts in athymic nude mice
Photodiagnosis Photodyn Ther, 4 (4), 237-41
DOI 10.1016/j.pdpdt.2007.08.001, PubMed 25047558 -
Photochemically induced gene silencing using small interfering RNA molecules in combination with lipid carriers
Oligonucleotides, 17 (2), 166-73
DOI 10.1089/oli.2007.0076, PubMed 17638521 -
Targeted cancer therapy with a novel low-dose rate alpha-emitting radioimmunoconjugate
Blood, 110 (6), 2049-56
DOI 10.1182/blood-2007-01-066803, PubMed 17536011 -
A one-step method for determining the maximum number of bound antibodies, and the affinity and association rate constants for antibody binding
Nucl Med Commun, 28 (9), 742-7
DOI 10.1097/MNM.0b013e3282e2a86b, PubMed 17667754 -
Chromosomal 20q gain in the DNA diploid component of aneuploid colorectal carcinomas
Int J Cancer, 120 (12), 2734-8
DOI 10.1002/ijc.22537, PubMed 17354231 -
Photochemically enhanced delivery of a cell-penetrating peptide nucleic acid conjugate targeting human telomerase reverse transcriptase: effects on telomere status and proliferative potential of human prostate cancer cells
Cell Prolif, 40 (6), 905-20
DOI 10.1111/j.1365-2184.2007.00470.x, PubMed 18021178 -
Inhibitory effects of oxaliplatin in experimental radiation treatment of colorectal carcinoma: does oxaliplatin improve 5-fluorouracil-dependent radiosensitivity?
Radiother Oncol, 86 (3), 428-34
DOI 10.1016/j.radonc.2007.10.012, PubMed 18006097 -
Dynamic contrast-enhanced magnetic resonance imaging of human melanoma xenografts with necrotic regions
J Magn Reson Imaging, 26 (1), 133-43
DOI 10.1002/jmri.20939, PubMed 17659570 -
Photostability of commercial sunscreens upon sun exposure and irradiation by ultraviolet lamps
BMC Dermatol, 7, 1
DOI 10.1186/1471-5945-7-1, PubMed 17324264 -
Comment on "the effects on human health from stratospheric ozone depletion and its interactions with climate change" by M. Norval, A. P. Cullen, F. R. de Gruijl, J. Longstreth, Y. Takizawa, R. M. Lucas, F. P. Noonan and J. C. van der Leun, Photochem. Photobiol. Sci., 2007, 6, 232
Photochem Photobiol Sci, 6 (8), 912-5; discussion 916-8
DOI 10.1039/b705482c, PubMed 17668123 -
Computed tomography enhancement characteristics of lymphomatous lymph nodes of the neck
Dentomaxillofac Radiol, 36 (4), 234-6
DOI 10.1259/dmfr/22615187, PubMed 17536092 -
Radiobiological responses for two cell lines following continuous low dose-rate (CLDR) and pulsed dose rate (PDR) brachytherapy
Acta Oncol, 46 (5), 602-11
DOI 10.1080/02841860600978981, PubMed 17562436 -
Characterization of the FAM110 gene family
Genomics, 90 (1), 14-27
DOI 10.1016/j.ygeno.2007.03.002, PubMed 17499476 -
Reconstruction of a ring applicator using CT imaging: impact of the reconstruction method and applicator orientation
Phys Med Biol, 52 (16), 4893-904
DOI 10.1088/0031-9155/52/16/012, PubMed 17671342 -
Topical applications of iron chelators in photosensitization
Photochem Photobiol Sci, 6 (12), 1268-74
DOI 10.1039/b703861e, PubMed 18046481 -
Milestones in the development of photodynamic therapy and fluorescence diagnosis
Photochem Photobiol Sci, 6 (12), 1234-45
DOI 10.1039/b705461k, PubMed 18046478 -
Biological activity of 5-aminolevulinic acid and its methyl ester after storage under different conditions
J Photochem Photobiol B, 87 (2), 67-72
DOI 10.1016/j.jphotobiol.2007.01.003, PubMed 17350278 -
Log normal distribution of cellular uptake of radioactivity
J Nucl Med, 48 (2), 327; author reply 327-8
PubMed 17268032 -
Prostate cancer survival is dependent on season of diagnosis
Prostate, 67 (12), 1362-70
DOI 10.1002/pros.20577, PubMed 17624920 -
Preparation of TH227-labeled radioimmunoconjugates, assessment of serum stability and antigen binding ability
Cancer Biother Radiopharm, 22 (3), 431-7
DOI 10.1089/cbr.2006.321, PubMed 17651051 -
Metabolic mapping by use of high-resolution magic angle spinning 1H MR spectroscopy for assessment of apoptosis in cervical carcinomas
BMC Cancer, 7, 11
DOI 10.1186/1471-2407-7-11, PubMed 17233882 -
A new method for photodynamic therapy of melanotic melanoma -- effects of depigmentation with violet light photodynamic therapy
J Environ Pathol Toxicol Oncol, 26 (3), 165-72
DOI 10.1615/jenvironpatholtoxicoloncol.v26.i3.10, PubMed 18197832 -
Photochemical internalization for the treatment of malignant gliomas
PROC SPIE, 6424, 64242C
DOI 10.1117/12.705086 -
Evaluation of the binding of radiolabeled rituximab to CD20-positive lymphoma cells: an in vitro feasibility study concerning low-dose-rate radioimmunotherapy with the alpha-emitter 227Th
Cancer Biother Radiopharm, 22 (4), 469-79
DOI 10.1089/cbr.2007.371, PubMed 17803441 -
The effect of lidocaine on PpIX photobleaching and outcome of ALA-PDT in vitro
Photodiagnosis Photodyn Ther, 4 (4), 249-53
DOI 10.1016/j.pdpdt.2007.10.002, PubMed 25047561 -
Colon cancer: prognosis for different latitudes, age groups and seasons in Norway
J Photochem Photobiol B, 89 (2-3), 148-55
DOI 10.1016/j.jphotobiol.2007.09.003, PubMed 18029190 -
Proton therapy - a systematic review of clinical effectiveness
Radiother Oncol, 83 (2), 123-32
DOI 10.1016/j.radonc.2007.03.001, PubMed 17499374 -
Now you see it... Imaging in radiotherapy treatment planning and delivery
Radiother Oncol, 85 (2), 173-5
DOI 10.1016/j.radonc.2007.11.001, PubMed 18022267 -
Introduction to the special issue on photodynamic therapy and photodetection
Photochem. Photobiol. Sci., 6 (12), 1233
DOI 10.1039/b716101h -
Quality assurance of dosimetry and the impact on sample size in randomized clinical trials
Radiother Oncol, 86 (2), 195-9
DOI 10.1016/j.radonc.2007.07.001, PubMed 17727987 -
Season of diagnosis is a predictor of cancer survival. Sun-induced vitamin D may be involved: a possible role of sun-induced Vitamin D
J Steroid Biochem Mol Biol, 103 (3-5), 675-8
DOI 10.1016/j.jsbmb.2006.12.031, PubMed 17229569 -
Seasonal and geographical variations in lung cancer prognosis in Norway. Does Vitamin D from the sun play a role?
Lung Cancer, 55 (3), 263-70
DOI 10.1016/j.lungcan.2006.11.013, PubMed 17207891 -
Fluctuating and diffusion-limited hypoxia in hypoxia-induced metastasis
Clin Cancer Res, 13 (7), 1971-8
DOI 10.1158/1078-0432.CCR-06-1967, PubMed 17360973 -
Consequences of leaf calibration errors on IMRT delivery
Phys Med Biol, 52 (4), 1147-56
DOI 10.1088/0031-9155/52/4/019, PubMed 17264376 -
Early changes in apparent diffusion coefficient predict the quantitative antitumoral activity of capecitabine, oxaliplatin, and irradiation in HT29 xenografts in athymic nude mice
Neoplasia, 9 (5), 392-400
DOI 10.1593/neo.07154, PubMed 17534444 -
Noninvasive monitoring of radiation-induced treatment response using proton magnetic resonance spectroscopy and diffusion-weighted magnetic resonance imaging in a colorectal tumor model
Radiother Oncol, 85 (2), 187-94
DOI 10.1016/j.radonc.2007.09.009, PubMed 17937968 -
Is the seasonal variation in cancer prognosis caused by sun-induced folate degradation?
Med Hypotheses, 69 (1), 182-5
DOI 10.1016/j.mehy.2006.07.063, PubMed 17197108 -
Radiotherapy adapted to spatial and temporal variability in tumor hypoxia
Int J Radiat Oncol Biol Phys, 68 (5), 1496-504
DOI 10.1016/j.ijrobp.2007.04.027, PubMed 17674980 -
On the parameter describing the generalised equivalent uniform dose (gEUD) for tumours
Phys Med, 23 (3-4), 100-6
DOI 10.1016/j.ejmp.2007.09.001, PubMed 17962057 -
A novel checkpoint mechanism regulating the G1/S transition
Genes Dev, 21 (6), 649-54
DOI 10.1101/gad.421807, PubMed 17369398 -
Assessment of microvascular density, extracellular volume fraction, and radiobiological hypoxia in human melanoma xenografts by dynamic contrast-enhanced MRI
J Magn Reson Imaging, 26 (4), 1033-42
DOI 10.1002/jmri.21110, PubMed 17896373 -
Y1068 phosphorylation is the most sensitive target of disulfonated tetraphenylporphyrin-based photodynamic therapy on epidermal growth factor receptor
Biochem Pharmacol, 74 (2), 226-35
DOI 10.1016/j.bcp.2007.04.018, PubMed 17531956 -
Targeted delivery and enhanced cytotoxicity of cetuximab-saporin by photochemical internalization in EGFR-positive cancer cells
Mol Pharm, 4 (2), 241-51
DOI 10.1021/mp060105u, PubMed 17263556 -
A novel method for mapping the heterogeneity in blood supply to normal and malignant tissues in the mouse dorsal window chamber
Microvasc Res, 75 (2), 179-87
DOI 10.1016/j.mvr.2007.06.009, PubMed 17688890
Publications 2006
-
Influence of light fluence rate on the effects of photodynamic therapy in an orthotopic rat glioma model
J Neurosurg, 104 (1), 109-17
DOI 10.3171/jns.2006.104.1.109, PubMed 16509154 -
Porphyrin formation in actinic keratosis and basal cell carcinoma after topical application of methyl 5-aminolevulinate
J Invest Dermatol, 126 (2), 265-71
DOI 10.1038/sj.jid.5700048, PubMed 16374471 -
Photochemical internalization (PCI): A novel technology for activation of endocytosed therapeutic agents.
Med Laser Appl, 21, 239-251
DOI 10.1016/j.mla.2006.08.004, PublikaID 73 -
Photochemically enhanced adenoviral transduction in a multicellular environment
Photochem Photobiol Sci, 5 (4), 411-21
DOI 10.1039/b515066c, PubMed 16583022 -
Photochemically enhanced transduction of polymer-complexed adenovirus targeted to the epidermal growth factor receptor
J Gene Med, 8 (3), 286-97
DOI 10.1002/jgm.853, PubMed 16342300 -
In vitro and in vivo photosensitization by protoporphyrins possessing different lipophilicities and vertical localization in the membrane
Photochem Photobiol, 82 (5), 1319-25
DOI 10.1562/2006-04-02-RA-865, PubMed 16740058 -
Fluctuations in pO2 in irradiated human melanoma xenografts
Radiat Res, 165 (1), 16-25
DOI 10.1667/rr3491.1, PubMed 16392958 -
The effect of dimethylsulfoxide, 1-[2-(decylthio)ethyl]azacyclopentan-2-one and Labrafac(®)CC on porphyrin formation in normal mouse skin during topical application of methyl 5-aminolevulinate: A fluorescence and extraction study
Photodiagnosis Photodyn Ther, 3 (1), 27-33
DOI 10.1016/S1572-1000(05)00109-2, PubMed 25049025 -
The effect of skin permeation enhancers on the formation of porphyrins in mouse skin during topical application of the methyl ester of 5-aminolevulinic acid
J Photochem Photobiol B, 83 (2), 94-7
DOI 10.1016/j.jphotobiol.2005.12.003, PubMed 16442808 -
Initial evaluation of (227)Th-p-benzyl-DOTA-rituximab for low-dose rate alpha-particle radioimmunotherapy
Nucl Med Biol, 33 (2), 271-9
DOI 10.1016/j.nucmedbio.2005.12.004, PubMed 16546683 -
Cellular response to 5-fluorouracil (5-FU) in 5-FU-resistant colon cancer cell lines during treatment and recovery
Mol Cancer, 5, 20
DOI 10.1186/1476-4598-5-20, PubMed 16709241 -
Photochemical internalization (PCI): a new modality for light activation of endocytosed therapeuticals
J Environ Pathol Toxicol Oncol, 25 (1-2), 521-36
DOI 10.1615/jenvironpatholtoxicoloncol.v25.i1-2.330, PubMed 16566739 -
Influence of formulation factors on methyl-ALA-induced protoporphyrin IX accumulation in vivo
Photodiagnosis Photodyn Ther, 3 (3), 190-201
DOI 10.1016/j.pdpdt.2006.03.007, PubMed 25049154 -
Topical bioadhesive patch systems enhance selectivity of protoporphyrin IX accumulation
Photochem Photobiol, 82 (3), 670-5
DOI 10.1562/2005-08-08-RA-641, PubMed 16475870 -
Assessment of fraction of radiobiologically hypoxic cells in human melanoma xenografts by dynamic contrast-enhanced MRI
Magn Reson Med, 55 (4), 874-82
DOI 10.1002/mrm.20852, PubMed 16506163 -
Photochemically mediated delivery of AdhCMV-TRAIL augments the TRAIL-induced apoptosis in colorectal cancer cell lines
Cancer Biol Ther, 5 (11), 1511-20
DOI 10.4161/cbt.5.11.3301, PubMed 17012835 -
Photochemical treatment with endosomally localized photosensitizers enhances the number of adenoviruses in the nucleus
J Gene Med, 8 (6), 707-18
DOI 10.1002/jgm.902, PubMed 16518880 -
Radiosensitization of colorectal carcinoma cell lines by histone deacetylase inhibition
Radiat Oncol, 1, 25
DOI 10.1186/1748-717X-1-25, PubMed 16887021 -
Flow cytometry-sorted non-viable endotoxin-treated human monocytes are strongly procoagulant
Thromb Haemost, 96 (1), 29-37
DOI 10.1160/TH06-01-0052, PubMed 16807648 -
Calcium ionophore-induced de-encryption of tissue factor in monocytes is associated with extensive cell death
Thromb Res, 119 (5), 621-30
DOI 10.1016/j.thromres.2006.05.012, PubMed 16844202 -
Subcellular localization pattern of protoporphyrin IX is an important determinant for its photodynamic efficiency of human carcinoma and normal cell lines
J Photochem Photobiol B, 84 (3), 213-20
DOI 10.1016/j.jphotobiol.2006.03.006, PubMed 16709459 -
Contralateral breast doses following radiotherapy of the breast and regional lymph nodes: Measurements and treatment planning calculations
Radiother Oncol, 82 (3), 332-6
DOI 10.1016/j.radonc.2006.08.018, PubMed 16962677 -
[Rhythms, depressions and light]
Tidsskr Nor Laegeforen, 126 (8), 1044-7
PubMed 16619063 -
The influence of light and darkness on cutaneous fluorescence in mice
Luminescence, 21 (3), 159-63
DOI 10.1002/bio.900, PubMed 16502394 -
The influence of temperature on photodynamic cell killing in vitro with 5-aminolevulinic acid
J Photochem Photobiol B, 84 (2), 161-6
DOI 10.1016/j.jphotobiol.2006.02.009, PubMed 16624569 -
Topical application of 5-aminolaevulinic acid, methyl 5-aminolaevulinate and hexyl 5-aminolaevulinate on normal human skin
Br J Dermatol, 155 (4), 791-9
DOI 10.1111/j.1365-2133.2006.07484.x, PubMed 16965430 -
The history of PDT in Norway Part one: Identification of basic mechanisms of general PDT
Photodiagnosis Photodyn Ther, 4 (1), 3-11
DOI 10.1016/j.pdpdt.2006.11.002, PubMed 25047184 -
The history of PDT in Norway Part II. Recent advances in general PDT and ALA-PDT
Photodiagnosis Photodyn Ther, 4 (2), 80-7
DOI 10.1016/j.pdpdt.2006.11.001, PubMed 25047338 -
Biophysical aspects of photodynamic therapy
J Environ Pathol Toxicol Oncol, 25 (1-2), 7-28
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DNA polyplexes based on degradable oligoethylenimine-derivatives: combination with EGF receptor targeting and endosomal release functions
J Control Release, 116 (2), 115-22
DOI 10.1016/j.jconrel.2006.07.002, PubMed 16959361 -
Reversal of doxorubicin resistance in breast cancer cells by photochemical internalization
Int J Cancer, 119 (11), 2692-8
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Mechanism of radiosensitization by porphyrins
J Environ Pathol Toxicol Oncol, 25 (1-2), 293-306
DOI 10.1615/jenvironpatholtoxicoloncol.v25.i1-2.190, PubMed 16566725 -
Gene expressions and copy numbers associated with metastatic phenotypes of uterine cervical cancer
BMC Genomics, 7, 268
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The effect of folic acid on porphyrin synthesis in tumors and normal skin of mice treated with 5-aminolevulinic acid or methyl 5-aminolevulinate
Photochem Photobiol Sci, 5 (8), 755-9
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Adapting radiotherapy to hypoxic tumours
Phys Med Biol, 51 (19), 4903-21
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LET effects following neutron irradiation of lithium formate EPR dosimeters
Spectrochim Acta A Mol Biomol Spectrosc, 63 (4), 861-9
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Facilitated delivery of ALA to inaccessible regions via bioadhesive patch systems
J Environ Pathol Toxicol Oncol, 25 (1-2), 389-402
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Singlet oxygen in photosensitization
J Environ Pathol Toxicol Oncol, 25 (1-2), 29-50
DOI 10.1615/jenvironpatholtoxicoloncol.v25.i1-2.30, PubMed 16566709 -
[Health effects of sun and solariums]
Tidsskr Nor Laegeforen, 126 (15), 1945-6; author reply 1946
PubMed 16915324 -
[The photobiology of vitamin D--a topic of renewed focus]
Tidsskr Nor Laegeforen, 126 (8), 1048-52
PubMed 16619064 -
Synergistic and tumour selective effects of chemotherapy and ultrasound treatment
Cancer Lett, 232 (2), 206-13
DOI 10.1016/j.canlet.2005.02.020, PubMed 16458117 -
Eradication of p53-mutated head and neck squamous cell carcinoma xenografts using nonviral p53 gene therapy and photochemical internalization
Mol Ther, 13 (6), 1156-62
DOI 10.1016/j.ymthe.2006.02.003, PubMed 16564229 -
The importance of the depth distribution of melanin in skin for DNA protection and other photobiological processes
J Photochem Photobiol B, 82 (3), 194-8
DOI 10.1016/j.jphotobiol.2005.11.008, PubMed 16388960 -
EPR dosimetry of radiotherapy photon beams in inhomogeneous media using alanine films
Phys Med Biol, 51 (24), 6315-28
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CSPP and CSPP-L associate with centrosomes and microtubules and differently affect microtubule organization
J Cell Physiol, 209 (1), 199-210
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Changes in risk of death from breast cancer with season and latitude: sun exposure and breast cancer survival in Norway
Breast Cancer Res Treat, 102 (3), 323-8
DOI 10.1007/s10549-006-9331-8, PubMed 17028983 -
Transcriptome changes in a colon adenocarcinoma cell line in response to photochemical treatment as used in photochemical internalisation (PCI)
FEBS Lett, 580 (24), 5739-46
DOI 10.1016/j.febslet.2006.09.028, PubMed 17007842 -
Photochemical internalization of transgenes controlled by the heat-shock protein 70 promoter
Photochem Photobiol, 82 (3), 809-16
DOI 10.1562/2005-11-07-RA-731, PubMed 16420102 -
DNA damage induces Cdt1 proteolysis in fission yeast through a pathway dependent on Cdt2 and Ddb1
EMBO Rep, 7 (11), 1134-9
DOI 10.1038/sj.embor.7400827, PubMed 17039252 -
DNA damage responses in cell cycle G2 phase and mitosis--tracking and targeting
Anticancer Res, 26 (3A), 1909-16
PubMed 16827124 -
Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice
Cancer Res, 66 (13), 6699-707
DOI 10.1158/0008-5472.CAN-06-0983, PubMed 16818644 -
The KH-Tudor domain of a-kinase anchoring protein 149 mediates RNA-dependent self-association
Biochemistry, 45 (50), 14980-9
DOI 10.1021/bi061418y, PubMed 17154535 -
Photochemical internalization of therapeutic macromolecular agents: a novel strategy to kill multidrug-resistant cancer cells
J Pharmacol Exp Ther, 319 (2), 604-12
DOI 10.1124/jpet.106.109165, PubMed 16902053 -
Induction of apoptosis by hexaminolevulinate-mediated photodynamic therapy in human colon carcinoma cell line 320DM
J Environ Pathol Toxicol Oncol, 25 (1-2), 159-71
DOI 10.1615/jenvironpatholtoxicoloncol.v25.i1-2.90, PubMed 16566715 -
Gain of chromosome 6p is an infrequent cause of increased PIM1 expression in B-cell non-Hodgkin's lymphomas
Leukemia, 20 (3), 539-42
DOI 10.1038/sj.leu.2404094, PubMed 16437153 -
Mechanistic investigation and implications of photodynamic therapy induction of vascular endothelial growth factor in prostate cancer
Cancer Res, 66 (11), 5633-40
DOI 10.1158/0008-5472.CAN-06-0604, PubMed 16740700 -
Photodegradation of 5-methyltetrahydrofolate: biophysical aspects
Photochem Photobiol, 82 (6), 1651-5
DOI 10.1562/2006-06-09-RA-915, PubMed 16879038 -
Optimization of tumour control probability in hypoxic tumours by radiation dose redistribution: a modelling study
Phys Med Biol, 52 (2), 499-513
DOI 10.1088/0031-9155/52/2/013, PubMed 17202629 -
Dose optimisation in single plane interstitial brachytherapy
Radiother Oncol, 81 (1), 105-11
DOI 10.1016/j.radonc.2006.08.021, PubMed 17005279 -
Dose painting: art or science?
Radiother Oncol, 79 (3), 245-8
DOI 10.1016/j.radonc.2006.05.002, PubMed 16725221 -
Measurement of lipid oxidation and porphyrins in high oxygen modified atmosphere and vacuum-packed minced turkey and pork meat by fluorescence spectra and images
Meat Sci, 73 (3), 511-20
DOI 10.1016/j.meatsci.2006.02.001, PubMed 22062491 -
Influence of human serum albumin on photodegradation of folic acid in solution
Photochem Photobiol, 82 (3), 817-22
DOI 10.1562/2005-11-23-RA-739, PubMed 16454580 -
Analysis of normal tissue complication probability of the lung using a reliability model
Acta Oncol, 45 (5), 610-7
DOI 10.1080/02841860600658245, PubMed 16864177 -
Photochemically stimulated drug delivery increases the cytotoxicity and specificity of EGF-saporin
J Control Release, 111 (1-2), 165-73
DOI 10.1016/j.jconrel.2005.12.002, PubMed 16466823 -
Active photosensitizers in butter detected by fluorescence spectroscopy and multivariate curve resolution
J Agric Food Chem, 54 (26), 10197-204
DOI 10.1021/jf0621166, PubMed 17177560 -
Influence of storage time and color of light on photooxidation in cheese: A study based on sensory analysis and fluorescence spectroscopy
Int. Dairy J., 16 (10), 1218-1226
DOI 10.1016/j.idairyj.2005.10.023 -
Spectroscopic measurements of photoinduced processes in human skin after topical application of the hexyl ester of 5-aminolevulinic acid
J Environ Pathol Toxicol Oncol, 25 (1-2), 307-20
DOI 10.1615/jenvironpatholtoxicoloncol.v25.i1-2.200, PubMed 16566726 -
Msh2 deficiency increases susceptibility to benzo[a]pyrene-induced lymphomagenesis
Int J Cancer, 118 (11), 2899-902
DOI 10.1002/ijc.21686, PubMed 16381012 -
A stochastic model of cancer initiation including a bystander effect
J Theor Biol, 241 (4), 751-64
DOI 10.1016/j.jtbi.2006.01.013, PubMed 16499930
Publications 2005
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The Escherichia coli baby cell column: a novel cell synchronization method provides new insight into the bacterial cell cycle
Mol Microbiol, 57 (2), 380-91
DOI 10.1111/j.1365-2958.2005.04693.x, PubMed 15978072 -
Lipid cubic phases for improved topical drug delivery in photodynamic therapy
J Control Release, 106 (3), 350-60
DOI 10.1016/j.jconrel.2005.05.010, PubMed 15967535 -
Site-specific drug delivery by photochemical internalization enhances the antitumor effect of bleomycin
Clin Cancer Res, 11 (23), 8476-85
DOI 10.1158/1078-0432.CCR-05-1245, PubMed 16322311 -
Porphyrin-related photosensitizers for cancer imaging and therapeutic applications
J Microsc, 218 (Pt 2), 133-47
DOI 10.1111/j.1365-2818.2005.01471.x, PubMed 15857375 -
Photochemical enhancement of gene delivery to glioblastoma cells is dependent on the vector applied
Anticancer Res, 25 (1A), 291-7
PubMed 15816550 -
Fluctuations in pO2 in poorly and well-oxygenated spontaneous canine tumors before and during fractionated radiation therapy
Radiother Oncol, 77 (2), 220-6
DOI 10.1016/j.radonc.2005.09.009, PubMed 16257074 -
pH dependent uptake of porphyrin-type photosensitizers by solid tumor cells in vitro is not induced by modification of transmembrane potential
Cancer Lett, 222 (1), 39-47
DOI 10.1016/j.canlet.2004.09.032, PubMed 15837539 -
Bystander effects in UV-induced genomic instability: antioxidants inhibit delayed mutagenesis induced by ultraviolet A and B radiation
J Carcinog, 4, 11
DOI 10.1186/1477-3163-4-11, PubMed 16091149 -
Bystander effects may modulate ultraviolet A and B radiation-induced delayed mutagenesis
Radiat Res, 163 (3), 289-95
DOI 10.1667/rr3305, PubMed 15733036 -
Multiplex polymerase chain reaction analysis of UV-A- and UV-B-induced delayed and early mutations in V79 Chinese hamster cells
Photochem Photobiol, 81 (1), 114-9
DOI 10.1562/2004-05-19-RA-174, PubMed 15453821 -
Comparative analyses of the dynamic properties of the bladder wall studied by repetitive pelvic CT scans of patients and cryo-sections of cadavers
Br J Radiol, 78 (930), 528-32
DOI 10.1259/bjr/82990907, PubMed 15900058 -
ALA-induced porphyrin formation and fluorescence in synovitis tissue In-vitro and in vivo studies
Photodiagnosis Photodyn Ther, 2 (4), 299-307
DOI 10.1016/S1572-1000(05)00107-9, PubMed 25048871 -
Transgene delivery and gelonin cytotoxicity enhanced by photochemical internalization in fibroblast-like synoviocytes (FLS) from rheumatoid arthritis patients
Photochem Photobiol Sci, 4 (4), 341-7
DOI 10.1039/b416521g, PubMed 15803204 -
Enhanced photodynamic destruction of a transplantable fibrosarcoma using photochemical internalisation of gelonin
Br J Cancer, 92 (11), 2004-9
DOI 10.1038/sj.bjc.6602600, PubMed 15886704 -
Pharmaceutical analysis of 5-aminolevulinic acid in solution and in tissues
J Photochem Photobiol B, 82 (1), 59-71
DOI 10.1016/j.jphotobiol.2005.08.007, PubMed 16242952 -
PCI-enhanced adenoviral transduction employs the known uptake mechanism of adenoviral particles
Cancer Gene Ther, 12 (5), 439-48
DOI 10.1038/sj.cgt.7700808, PubMed 15678152 -
Genome-wide estimation of transcript concentrations from spotted cDNA microarray data
Nucleic Acids Res, 33 (17), e143
DOI 10.1093/nar/gni141, PubMed 16204447 -
Translocation t(14;18) and gain of chromosome 18/BCL2: effects on BCL2 expression and apoptosis in B-cell non-Hodgkin's lymphomas
Leukemia, 19 (12), 2313-23
DOI 10.1038/sj.leu.2403954, PubMed 16193090 -
Intratumor heterogeneity in blood perfusion in orthotopic human melanoma xenografts assessed by dynamic contrast-enhanced magnetic resonance imaging
J Magn Reson Imaging, 21 (6), 792-800
DOI 10.1002/jmri.20321, PubMed 15906326 -
Cell specific effects of polyunsaturated fatty acids on 5-aminolevulinic acid based photosensitization
Photochem Photobiol Sci, 4 (4), 383-9
DOI 10.1039/b502000j, PubMed 15803209 -
Comparison of tumor blood perfusion assessed by dynamic contrast-enhanced MRI with tumor blood supply assessed by invasive imaging
J Magn Reson Imaging, 21 (3), 272-81
DOI 10.1002/jmri.20265, PubMed 15723369 -
Changes in intratumor heterogeneity in blood perfusion in intradermal human melanoma xenografts during tumor growth assessed by DCE-MRI
Magn Reson Imaging, 23 (9), 961-6
DOI 10.1016/j.mri.2005.09.006, PubMed 16310112 -
The role of p27 in controlling the oxygen-dependent checkpoint of mammalian cells in late G1
Anticancer Res, 25 (3B), 2259-67
PubMed 16158973 -
Deferoxamine photosensitizes cancer cells in vitro
Biochem Biophys Res Commun, 332 (2), 388-91
DOI 10.1016/j.bbrc.2005.04.138, PubMed 15910749 -
Respiratory motion prediction by using the adaptive neuro fuzzy inference system (ANFIS)
Phys Med Biol, 50 (19), 4721-8
DOI 10.1088/0031-9155/50/19/020, PubMed 16177500 -
Formation of protoporphyrin IX from carboxylic- and amino-derivatives of 5-aminolevulinic acid
Photodiagnosis Photodyn Ther, 2 (2), 129-34
DOI 10.1016/S1572-1000(05)00012-8, PubMed 25048672 -
Kinetics of protoporphyrin IX formation in rat oral mucosa and skin after application of 5-aminolevulinic acid and its methylester
Photochem Photobiol, 81 (2), 394-7
DOI 10.1562/2004-04-02-RA-132, PubMed 15535733 -
The pheomelanin precursor 5-S-cysteinyldopa protects melanocytes from membrane damage induced by ultraviolet A radiation
Cancer Lett, 221 (2), 131-4
DOI 10.1016/j.canlet.2004.08.025, PubMed 15808398 -
Radiosensitization of tumours by porphyrins
Cancer Lett, 235 (1), 40-7
DOI 10.1016/j.canlet.2005.03.041, PubMed 15946797 -
Garlic arrests MDA-MB-435 cancer cells in mitosis, phosphorylates the proapoptotic BH3-only protein BimEL and induces apoptosis
Br J Cancer, 92 (9), 1773-81
DOI 10.1038/sj.bjc.6602537, PubMed 15827557 -
Response of malignant B lymphocytes to ionizing radiation: gene expression and genotype
Int J Cancer, 115 (6), 935-42
DOI 10.1002/ijc.20962, PubMed 15723354 -
Influence of light exposure on the kinetics of protoporphyrin IX formation in normal skin of hairless mice after application of 5-aminolevulinic acid methyl ester
J Invest Dermatol, 125 (5), 1039-44
DOI 10.1111/j.0022-202X.2005.23863.x, PubMed 16297207 -
Solar radiation, vitamin D and survival rate of colon cancer in Norway
J Photochem Photobiol B, 78 (3), 189-93
DOI 10.1016/j.jphotobiol.2004.11.004, PubMed 15708515 -
Choice of optimal wavelength for PDT: the significance of oxygen depletion
Photochem Photobiol, 81 (5), 1190-4
DOI 10.1562/2005-04-06-RA-478, PubMed 15934793 -
Telemedicine in radiotherapy: a study exploring remote treatment planning, supervision and economics
J Telemed Telecare, 11 (5), 245-50
DOI 10.1258/1357633054471858, PubMed 16035967 -
Ultraviolet photodegradation of folic acid
J Photochem Photobiol B, 80 (1), 47-55
DOI 10.1016/j.jphotobiol.2005.03.001, PubMed 15963436 -
Activin A suppresses neuroblastoma xenograft tumor growth via antimitotic and antiangiogenic mechanisms
Cancer Res, 65 (5), 1877-86
DOI 10.1158/0008-5472.CAN-04-2828, PubMed 15753386 -
Identification of a novel centrosome/microtubule-associated coiled-coil protein involved in cell-cycle progression and spindle organization
Oncogene, 24 (7), 1159-73
DOI 10.1038/sj.onc.1208267, PubMed 15580290 -
Season of diagnosis is a prognostic factor in Hodgkin's lymphoma: a possible role of sun-induced vitamin D
Br J Cancer, 93 (5), 571-4
DOI 10.1038/sj.bjc.6602722, PubMed 16136030 -
The tumor bed effect: increased metastatic dissemination from hypoxia-induced up-regulation of metastasis-promoting gene products
Cancer Res, 65 (6), 2387-96
DOI 10.1158/0008-5472.CAN-04-3039, PubMed 15781654 -
The influence of missing value imputation on detection of differentially expressed genes from microarray data
Bioinformatics, 21 (23), 4272-9
DOI 10.1093/bioinformatics/bti708, PubMed 16216830 -
Image quality preferences among radiographers and radiologists. A conjoint analysis
Radiography, 11 (3), 191-197
DOI 10.1016/j.radi.2005.03.002 -
The role of naturally occurring chlorophyll and porphyrins in light-induced oxidation of dairy products. A study based on fluorescence spectroscopy and sensory analysis
Int. Dairy J., 15 (4), 343-353
DOI 10.1016/j.idairyj.2004.08.009 -
Characterization of a novel Eph receptor tyrosine kinase, EphA10, expressed in testis
Biochim Biophys Acta, 1723 (1-3), 1-7
DOI 10.1016/j.bbagen.2005.01.011, PubMed 15777695
Publications 2004
-
Combination of boron neutron capture therapy and external beam radiotherapy for brain tumors
Int J Radiat Oncol Biol Phys, 58 (1), 267-77
DOI 10.1016/s0360-3016(03)01613-4, PubMed 14697448 -
Assessment of tumor blood perfusion by high-resolution dynamic contrast-enhanced MRI: a preclinical study of human melanoma xenografts
Magn Reson Med, 52 (2), 269-76
DOI 10.1002/mrm.20149, PubMed 15282808 -
Photochemical drug and gene delivery
Curr Opin Mol Ther, 6 (3), 279-87
PubMed 15264430 -
Transgene expression is increased by photochemically mediated transduction of polycation-complexed adenoviruses
Gene Ther, 11 (2), 152-60
DOI 10.1038/sj.gt.3302166, PubMed 14712299 -
Tumor-line specific pO(2) fluctuations in human melanoma xenografts
Int J Radiat Oncol Biol Phys, 58 (2), 403-9
DOI 10.1016/j.ijrobp.2003.09.049, PubMed 14751509 -
Signalling to the nucleus via A-kinase anchoring proteins
Symp Soc Exp Biol (56), 245-63
PubMed 15565886 -
On the selectivity of 5-aminolevulinic acid-induced protoporphyrin IX formation
Curr Med Chem Anticancer Agents, 4 (3), 301-16
DOI 10.2174/1568011043352984, PubMed 15134506 -
pH-dependent modification of lipophilicity of porphyrin-type photosensitizers
Photochem Photobiol, 79 (3), 242-7
DOI 10.1562/0031-8655(2004)79<242:pmolop>2.0.co;2, PubMed 15115296 -
pH-dependent modification of lipophilicity of porphyrin-type photosensitizers (vol 79, pg 242, 2004)
Photochem. Photobiol., 80 (2), 373
DOI 10.1562/2004-09-27-ER-330.1 -
Electrostatic properties of cells estimated by absorption and fluorescence spectroscopy
Cell Biochem Biophys, 41 (1), 1-10
DOI 10.1385/CBB:41:1:001, PubMed 15371636 -
Automated counting of mammalian cell colonies by means of a flat bed scanner and image processing
Cytometry A, 60 (2), 182-8
DOI 10.1002/cyto.a.20038, PubMed 15290719 -
Increased level of oxidative stress in genomically unstable cell clones
J Photochem Photobiol B, 74 (1), 23-8
DOI 10.1016/j.jphotobiol.2004.01.004, PubMed 15043843 -
Radiation improves the distribution and uptake of liposomal doxorubicin (caelyx) in human osteosarcoma xenografts
Cancer Res, 64 (2), 547-53
DOI 10.1158/0008-5472.can-03-0576, PubMed 14744768 -
Molecular characterizations of derivatives of HCT116 colorectal cancer cells that are resistant to the chemotherapeutic agent 5-fluorouracil
Int J Oncol, 24 (5), 1279-88
PubMed 15067352 -
Determination of hereditary mutations in the BRCA1 gene using archived serum samples and capillary electrophoresis
Anal Chem, 76 (15), 4406-9
DOI 10.1021/ac049788k, PubMed 15283579 -
Quantitative assessment of uptake and distribution of iron oxide particles (NC100150) in human melanoma xenografts by contrast-enhanced MRI
Magn Reson Med, 51 (4), 727-35
DOI 10.1002/mrm.20028, PubMed 15065245 -
Counteraction of pRb-dependent protection after extreme hypoxia by elevated ribonucleotide reductase
Cell Prolif, 37 (5), 367-83
DOI 10.1111/j.1365-2184.2004.00319.x, PubMed 15377335 -
Characterization of a novel immunoglobulin-like domain containing receptor
Biochem Biophys Res Commun, 323 (3), 970-8
DOI 10.1016/j.bbrc.2004.08.188, PubMed 15381095 -
Photochemical internalisation in drug and gene delivery
Adv Drug Deliv Rev, 56 (1), 95-115
DOI 10.1016/j.addr.2003.08.016, PubMed 14706447 -
Spectroscopic evidence of monomeric aluminium phthalocyanine tetrasulphonate in aqueous solutions
J Photochem Photobiol B, 75 (1-2), 107-10
DOI 10.1016/j.jphotobiol.2004.05.011, PubMed 15246357 -
Effectiveness of different light sources for 5-aminolevulinic acid photodynamic therapy
Lasers Med Sci, 19 (3), 139-49
DOI 10.1007/s10103-004-0314-x, PubMed 15503248 -
Erythrocytes-the 'house elves' of photodynamic therapy
Photochem Photobiol Sci, 3 (11-12), 981-9
DOI 10.1039/b403127j, PubMed 15570383 -
Photochemically enhanced gene delivery of EGF receptor-targeted DNA polyplexes
J Drug Target, 12 (4), 205-13
DOI 10.1080/10611860410001723090, PubMed 15506169 -
Melanin synthesis may sensitize melanocytes to oxidative DNA damage by ultraviolet A radiation and protect melanocytes from direct DNA damage by ultraviolet B radiation
Pigment Cell Res, 17 (5), 549-50
DOI 10.1111/j.1600-0749.2004.00168.x, PubMed 15357843 -
The response of malignant B lymphocytes to ionizing radiation: cell cycle arrest, apoptosis and protection against the cytotoxic effects of the mitotic inhibitor nocodazole
Radiat Res, 162 (4), 405-15
DOI 10.1667/rr3235, PubMed 15447042 -
Photodegradation and phototransformation of 5,10,15,20-tetrakis(m-hydroxyphenyl)bacteriochlorin (m-THPBC) in solution
Photochem Photobiol Sci, 3 (11-12), 999-1005
DOI 10.1039/b405138f, PubMed 15570386 -
Profound influence of microarray scanner characteristics on gene expression ratios: analysis and procedure for correction
BMC Genomics, 5 (1), 10
DOI 10.1186/1471-2164-5-10, PubMed 15018648 -
Intratumor chromosomal heterogeneity in advanced carcinomas of the uterine cervix
Int J Cancer, 111 (3), 358-66
DOI 10.1002/ijc.20258, PubMed 15221962 -
Sustained gene transfer and enhanced cell death following glucosylated-PEI-mediated p53 gene transfer with photochemical internalisation in p53-mutated head and neck carcinoma cells
Int J Oncol, 25 (6), 1575-81
PubMed 15547693 -
Enhanced gene transfer and cell death following p53 gene transfer using photochemical internalisation of glucosylated PEI-DNA complexes
J Gene Med, 6 (8), 884-94
DOI 10.1002/jgm.573, PubMed 15293347 -
Reflectance spectra of pigmented and nonpigmented skin in the UV spectral region
Photochem Photobiol, 80 (3), 450-5
DOI 10.1562/0031-8655(2004)080<0450:RSOPAN>2.0.CO;2, PubMed 15623329 -
Germinating fission yeast spores delay in G1 in response to UV irradiation
BMC Cell Biol, 5 (1), 40
DOI 10.1186/1471-2121-5-40, PubMed 15498101 -
Light-directed gene delivery by photochemical internalisation
Expert Opin Biol Ther, 4 (9), 1403-12
DOI 10.1517/14712598.4.9.1403, PubMed 15335308 -
Photochemically enhanced gene transfection increases the cytotoxicity of the herpes simplex virus thymidine kinase gene combined with ganciclovir
Cancer Gene Ther, 11 (7), 514-23
DOI 10.1038/sj.cgt.7700720, PubMed 15118758 -
Inhibitory targeting of checkpoint kinase signaling overrides radiation-induced cell cycle gene regulation: a therapeutic strategy in tumor cell radiosensitization?
Radiother Oncol, 72 (3), 305-10
DOI 10.1016/j.radonc.2004.07.002, PubMed 15450729 -
Ionizing radiation inhibits the PLK cell cycle gene in a G2 checkpoint-dependent manner
Anticancer Res, 24 (2B), 555-62
PubMed 15160994 -
Vitamin D3 from sunlight may improve the prognosis of breast-, colon- and prostate cancer (Norway)
Cancer Causes Control, 15 (2), 149-58
DOI 10.1023/B:CACO.0000019494.34403.09, PubMed 15017127 -
Thrombospondin-1 treatment prevents growth of dormant lung micrometastases after surgical resection and curative radiation therapy of the primary tumor in human melanoma xenografts
Int J Radiat Oncol Biol Phys, 58 (2), 493-9
DOI 10.1016/j.ijrobp.2003.09.030, PubMed 14751520 -
Increased metastatic dissemination in human melanoma xenografts after subcurative radiation treatment: radiation-induced increase in fraction of hypoxic cells and hypoxia-induced up-regulation of urokinase-type plasminogen activator receptor
Cancer Res, 64 (1), 13-8
DOI 10.1158/0008-5472.can-03-2658, PubMed 14729600 -
Flow cytometer for measurement of the light scattering of viral and other submicroscopic particles
Cytometry A, 57 (2), 94-9
DOI 10.1002/cyto.a.10115, PubMed 14750130 -
Photodynamic inhibition of enzymatic detachment of human cancer cells from a substratum
Biochim Biophys Acta, 1670 (1), 1-11
DOI 10.1016/j.bbagen.2003.10.013, PubMed 14729136 -
The effect of sub-lethal ALA-PDT on the cytoskeleton and adhesion of cultured human cancer cells
Biochim Biophys Acta, 1722 (1), 43-50
DOI 10.1016/j.bbagen.2004.11.011, PubMed 15716135 -
Photosensitization with protoporphyrin IX inhibits attachment of cancer cells to a substratum
Biochem Biophys Res Commun, 322 (2), 452-7
DOI 10.1016/j.bbrc.2004.07.132, PubMed 15325251 -
Electron paramagnetic resonance (EPR) dosimetry using lithium formate in radiotherapy: comparison with thermoluminescence (TL) dosimetry using lithium fluoride rods
Phys Med Biol, 49 (20), 4701-15
DOI 10.1088/0031-9155/49/20/003, PubMed 15566169
Publications 2003
-
Photochemical internalization (PCI)--a novel technology for release of macromolecules from endocytic vesicles
Oftalmologia, 56 (1), 67-71
PubMed 12886687 -
Temporal heterogeneity in oxygen tension in human melanoma xenografts
Br J Cancer, 89 (2), 350-6
DOI 10.1038/sj.bjc.6601047, PubMed 12865929 -
pH, serum proteins and ionic strength influence the uptake of merocyanine 540 by WiDr cells and its interaction with membrane structures
Bioelectrochemistry, 59 (1-2), 1-10
DOI 10.1016/s1567-5394(02)00155-x, PubMed 12699813 -
Induction of delayed mutations and chromosomal instability in fibroblasts after UVA-, UVB-, and X-radiation
Cancer Res, 63 (7), 1464-9
PubMed 12670891 -
Comparative analyses of the dynamic properties of the rectum studied by cryo-sections of human cadavers and pelvic CT scans of patients
Br J Radiol, 76 (902), 104-8
DOI 10.1259/bjr/75640835, PubMed 12642278 -
Photochemical internalization enhances the cytotoxic effect of the protein toxin gelonin and transgene expression in sarcoma cells
Photochem Photobiol, 78 (3), 283-9
DOI 10.1562/0031-8655(2003)078<0283:pietce>2.0.co;2, PubMed 14556316 -
Radiation therapy induced changes in male sex hormone levels in rectal cancer patients
Radiother Oncol, 68 (3), 249-53
DOI 10.1016/s0167-8140(03)00120-8, PubMed 13129632 -
A spectroscopic study of the photobleaching of protoporphyrin IX in solution
Lasers Med Sci, 18 (1), 56-62
DOI 10.1007/s10103-002-0254-2, PubMed 12627275 -
Photochemical internalization of a peptide nucleic acid targeting the catalytic subunit of human telomerase
Cancer Res, 63 (13), 3490-4
PubMed 12839932 -
Definitive radiotherapy of prostate cancer: the possible role of staging lymphadenectomy
Int J Radiat Oncol Biol Phys, 57 (1), 33-41
DOI 10.1016/s0360-3016(03)00428-0, PubMed 12909213 -
pH effects on the cellular uptake of four photosensitizing drugs evaluated for use in photodynamic therapy of cancer
Cancer Lett, 195 (1), 73-80
DOI 10.1016/s0304-3835(03)00150-2, PubMed 12767514 -
Intratumour heterogeneity in the uptake of macromolecular therapeutic agents in human melanoma xenografts
Br J Cancer, 88 (2), 291-7
DOI 10.1038/sj.bjc.6600680, PubMed 12610516 -
Photochemically enhanced gene delivery with cationic lipid formulations
Photochem. Photobiol. Sci., 2 (4), 407-411
DOI 10.1039/b211880g -
Photochemically enhanced gene delivery with cationic lipid formulations
Photochem Photobiol Sci, 2 (4), 407-11
DOI 10.1039/b211880g, PubMed 12760539 -
Light directed gene transfer by photochemical internalisation
Curr Gene Ther, 3 (2), 89-112
DOI 10.2174/1566523034578438, PubMed 12653404 -
Pigmented melanocytes are protected against ultraviolet-A-induced membrane damage
J Invest Dermatol, 121 (3), 564-9
DOI 10.1046/j.1523-1747.2003.12418.x, PubMed 12925216 -
Changes in treatment volume of hormonally treated and untreated cancerous prostate and its impact on rectal dose
Acta Oncol, 42 (1), 10-4
DOI 10.1080/0891060310002177, PubMed 12665325 -
Pharmacology of protoporphyrin IX in nude mice after application of ALA and ALA esters
Int J Cancer, 103 (1), 132-5
DOI 10.1002/ijc.10802, PubMed 12455066 -
An outline of the hundred-year history of PDT
Anticancer Res, 23 (5A), 3591-600
PubMed 14666654 -
Intra-G1 arrest in response to UV irradiation in fission yeast
Proc Natl Acad Sci U S A, 100 (19), 10758-63
DOI 10.1073/pnas.1833769100, PubMed 12960401 -
Brachytherapy for prostate cancer: a systematic review of clinical and cost effectiveness
Eur Urol, 44 (1), 40-6
DOI 10.1016/s0302-2838(03)00187-8, PubMed 12814673 -
Repression of mRNA for the PLK cell cycle gene after DNA damage requires BRCA1
Oncogene, 22 (55), 8952-5
DOI 10.1038/sj.onc.1207000, PubMed 14654792 -
Information technology in action: the example of Norway
Stud Health Technol Inform, 96, 186-9
PubMed 15061543 -
Antiangiogenic treatment with thrombospondin-1 enhances primary tumor radiation response and prevents growth of dormant pulmonary micrometastases after curative radiation therapy in human melanoma xenografts
Cancer Res, 63 (14), 4055-61
PubMed 12874006 -
Hypoxia-induced irreversible S-phase arrest involves down-regulation of cyclin A
Cell Prolif, 36 (6), 321-32
DOI 10.1046/j.1365-2184.2003.00288.x, PubMed 14710850 -
Circles in the sand
EMBO Rep, 4 (7), 661-5
DOI 10.1038/sj.embor.embor888, PubMed 12835752 -
AKAP149 is a novel PP1 specifier required to maintain nuclear envelope integrity in G1 phase
J Cell Sci, 116 (Pt 11), 2237-46
DOI 10.1242/jcs.00432, PubMed 12697839 -
Photodynamic effect of hypericin and a water-soluble derivative on isolated crayfish neuron and surrounding glial cells
J Photochem Photobiol B, 72 (1-3), 27-33
DOI 10.1016/j.jphotobiol.2003.08.008, PubMed 14644563
Publications 2002
-
Neutron capture therapy of intracerebral melanoma: enhanced survival and cure after blood-brain barrier opening to improve delivery of boronophenylalanine
Int J Radiat Oncol Biol Phys, 52 (3), 858-68
DOI 10.1016/s0360-3016(01)02734-1, PubMed 11849812 -
DNA-containing extracellular 50-nm particles in the ileal Peyer's patch of sheep
Eur J Cell Biol, 81 (2), 69-76
DOI 10.1078/0171-9335-00225, PubMed 11893084 -
Side effects and quality of life after inadvertent radiation overdosage in brachytherapy of head-and-neck cancer
Int J Radiat Oncol Biol Phys, 52 (4), 944-52
DOI 10.1016/s0360-3016(01)02726-2, PubMed 11958887 -
Long-term renal function after treatment for malignant germ-cell tumours
Ann Oncol, 13 (2), 222-8
DOI 10.1093/annonc/mdf048, PubMed 11885998 -
The stability of 5-aminolevulinic acid in solution
J Photochem Photobiol B, 67 (3), 187-93
DOI 10.1016/s1011-1344(02)00278-6, PubMed 12167318 -
Proliferation-dependent expression and phosphorylation of pRB in B cell non-Hodgkin's lymphomas: dependence on RB1 copy number
Leukemia, 16 (8), 1549-55
DOI 10.1038/sj.leu.2402644, PubMed 12145697 -
N-myc oncogene overexpression down-regulates IL-6; evidence that IL-6 inhibits angiogenesis and suppresses neuroblastoma tumor growth
Oncogene, 21 (22), 3552-61
DOI 10.1038/sj.onc.1205440, PubMed 12032857 -
Light-induced adenovirus gene transfer, an efficient and specific gene delivery technology for cancer gene therapy
Cancer Gene Ther, 9 (4), 365-71
DOI 10.1038/sj.cgt.7700447, PubMed 11960287 -
Photochemical transfection: a technology for efficient light-directed gene delivery
Somat Cell Mol Genet, 27 (1-6), 97-113
DOI 10.1023/a:1022979806314, PubMed 12774944 -
Reprogramming fibroblasts to express T-cell functions using cell extracts
Nat Biotechnol, 20 (5), 460-6
DOI 10.1038/nbt0502-460, PubMed 11981558 -
Associations between gene expressions in breast cancer and patient survival
Hum Genet, 111 (4-5), 411-20
DOI 10.1007/s00439-002-0804-5, PubMed 12384785 -
Modeling volume effects of experimental brachytherapy in the rat rectum: uncovering the limitations of a radiobiologic concept
Int J Radiat Oncol Biol Phys, 53 (4), 1014-22
DOI 10.1016/s0360-3016(02)02835-3, PubMed 12095571 -
Noninvasive fluorescence excitation spectroscopy during application of 5-aminolevulinic acid in vivo
Photochem Photobiol Sci, 1 (10), 745-8
DOI 10.1039/b203459j, PubMed 12656473 -
Photosensitizing effect of protoporphyrin IX in pigmented melanoma of mice
Biochem Biophys Res Commun, 297 (3), 468-72
DOI 10.1016/s0006-291x(02)02238-6, PubMed 12270116 -
Protoporphyrin IX fluorescence kinetics in UV-induced tumours and normal skin of hairless mice after topical application of 5-aminolevulinic acid methyl ester
J Photochem Photobiol B, 67 (1), 11-7
DOI 10.1016/s1011-1344(02)00269-5, PubMed 12007462 -
Topical application of 5-aminolevulinic acid and its methylester, hexylester and octylester derivatives: considerations for dosimetry in mouse skin model
Photochem Photobiol, 76 (3), 329-34
DOI 10.1562/0031-8655(2002)076<0329:taoaaa>2.0.co;2, PubMed 12403455 -
Temperature effect on accumulation of protoporphyrin IX after topical application of 5-aminolevulinic acid and its methylester and hexylester derivatives in normal mouse skin
Photochem Photobiol, 76 (4), 452-6
DOI 10.1562/0031-8655(2002)076<0452:teoaop>2.0.co;2, PubMed 12405155 -
Production of protoporphyrin IX from 5-aminolevulinic acid and two of its esters in cells in vitro and tissues in vivo
Cell Mol Biol (Noisy-le-grand), 48 (8), 911-6
PubMed 12699250 -
Effects of growth factors on growth and radiation sensitivity of the human breast cancer cell line T-47D
Oncol Rep, 9 (2), 397-403
PubMed 11836616 -
Transfer of protoporphyrin IX between cells
Photochem Photobiol, 76 (5), 526-9
DOI 10.1562/0031-8655(2002)076<0526:topibc>2.0.co;2, PubMed 12462648 -
Activation of phosphatidylinositol 3-kinase is important for erythropoietin-induced erythropoiesis from CD34(+) hematopoietic progenitor cells
Exp Hematol, 30 (9), 990-1000
DOI 10.1016/s0301-472x(02)00868-8, PubMed 12225790 -
[Brachytherapy in prostatic cancer]
Tidsskr Nor Laegeforen, 122 (29), 2795-8
PubMed 12523149 -
Photochemical transfection. Light-induced, site-directed gene delivery
Methods Mol Med, 69, 123-35
DOI 10.1385/1-59259-141-8:123, PubMed 11987772 -
The role of the cell cycle on the efficiency of photochemical gene transfection
Biochim Biophys Acta, 1570 (3), 210-8
DOI 10.1016/s0304-4165(02)00202-7, PubMed 12020812 -
Photochemical disruption of endocytic vesicles before delivery of drugs: a new strategy for cancer therapy
Br J Cancer, 86 (4), 652-7
DOI 10.1038/sj.bjc.6600138, PubMed 11870551 -
Hypoxia-associated spontaneous pulmonary metastasis in human melanoma xenografts: involvement of microvascular hot spots induced in hypoxic foci by interleukin 8
Br J Cancer, 86 (2), 301-8
DOI 10.1038/sj.bjc.6600052, PubMed 11870523 -
Hypoxia promotes lymph node metastasis in human melanoma xenografts by up-regulating the urokinase-type plasminogen activator receptor
Cancer Res, 62 (6), 1847-53
PubMed 11912164 -
Pulmonary and lymph node metastasis is associated with primary tumor interstitial fluid pressure in human melanoma xenografts
Cancer Res, 62 (3), 661-4
PubMed 11830516 -
The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma
N Engl J Med, 346 (25), 1937-47
DOI 10.1056/NEJMoa012914, PubMed 12075054 -
Cell cycle inhibitors and outcome after radiotherapy in bladder cancer patients
Acta Oncol, 41 (5), 463-70
DOI 10.1080/028418602320405069, PubMed 12442923 -
Phylloerythrin. mechanisms for cellular uptake and location, photosensitisation and spectroscopic evaluation
N Z Vet J, 50 (3), 104-10
DOI 10.1080/00480169.2002.36291, PubMed 16032220 -
Photochemical internalisation: a novel drug delivery system
Tumour Biol, 23 (2), 103-12
DOI 10.1159/000059713, PubMed 12065848 -
Weekly topical application of methyl aminolevulinate followed by light exposure delays the appearance of UV-induced skin tumours in mice
Arch Dermatol Res, 294 (5), 237-42
DOI 10.1007/s00403-002-0320-4, PubMed 12115027 -
A sample injection device for flow cytometers
Cytometry, 49 (2), 70-2
DOI 10.1002/cyto.10147, PubMed 12357462 -
Dye exclusion artifact in flow cytometers
Cytometry, 47 (3), 200-5
DOI 10.1002/cyto.10063, PubMed 11891725 -
A novel chk1-dependent G1/M checkpoint in fission yeast
J Cell Sci, 115 (Pt 18), 3609-18
DOI 10.1242/jcs.00004, PubMed 12186947 -
Photobleaching of hypericin bound to human serum albumin, cultured adenocarcinoma cells and nude mice skin
Photochem Photobiol, 76 (3), 320-8
DOI 10.1562/0031-8655(2002)076<0320:pohbth>2.0.co;2, PubMed 12403454 -
Systemic component of protoporphyrin IX production in nude mouse skin upon topical application of aminolevulinic acid depends on the application conditions
Photochem Photobiol, 75 (2), 172-7
DOI 10.1562/0031-8655(2002)075<0172:SCOPIP>2.0.CO;2, PubMed 11885562 -
Preoperative irradiation and surgery for recurrent rectal cancer. Will intraoperative radiotherapy (IORT) be of additional benefit? A prospective study
Radiother Oncol, 62 (2), 207-13
DOI 10.1016/s0167-8140(01)00486-8, PubMed 11937248
Publications 2001
-
Microvascular permeability to macromolecules in human melanoma xenografts assessed by contrast-enhanced MRI--intertumor and intratumor heterogeneity
Magn Reson Imaging, 19 (5), 723-30
DOI 10.1016/s0730-725x(01)00377-0, PubMed 11672631 -
Transvascular and interstitial transport of a 19 kDa linear molecule in human melanoma xenografts measured by contrast-enhanced magnetic resonance imaging
J Magn Reson Imaging, 14 (5), 608-16
DOI 10.1002/jmri.1226, PubMed 11747014 -
[The 2001 Nobel Prize in Physiology or Medicine]
Tidsskr Nor Laegeforen, 121 (30), 3500
PubMed 11808003 -
pH-dependent spectral properties of HpIX, TPPS2a, mTHPP and mTHPC
Photochem Photobiol, 74 (2), 246-52
DOI 10.1562/0031-8655(2001)074<0246:pdspoh>2.0.co;2, PubMed 11547562 -
Bystander effects in cell death induced by photodynamic treatment UVA radiation and inhibitors of ATP synthesis
Photochem Photobiol, 73 (4), 378-87
DOI 10.1562/0031-8655(2001)073<0378:beicdi>2.0.co;2, PubMed 11332033 -
Prognostic significance of recurrent chromosomal aberrations detected by comparative genomic hybridization in sporadic colorectal cancer
Int J Colorectal Dis, 16 (1), 38-45
DOI 10.1007/s003840000275, PubMed 11317696 -
5-Aminolaevulinic acid methyl ester transport on amino acid carriers in a human colon adenocarcinoma cell line
Photochem Photobiol, 73 (2), 164-9
DOI 10.1562/0031-8655(2001)073<0164:aameto>2.0.co;2, PubMed 11272730 -
Microvascular permeability of human melanoma xenografts to macromolecules: relationships to tumor volumetric growth rate, tumor angiogenesis, and VEGF expression
Microvasc Res, 61 (2), 187-98
DOI 10.1006/mvre.2001.2303, PubMed 11254398 -
Inter fraction variations in rectum and bladder volumes and dose distributions during high dose rate brachytherapy treatment of the uterine cervix investigated by repetitive CT-examinations
Radiother Oncol, 60 (3), 273-80
DOI 10.1016/s0167-8140(01)00386-3, PubMed 11514007 -
Fluorescence spectroscopy of normal mouse skin exposed to 5-aminolaevulinic acid and red light
J Photochem Photobiol B, 61 (1-2), 78-86
DOI 10.1016/s1011-1344(01)00149-x, PubMed 11485851 -
Radioimmunotherapy with alpha-particle emitters: microdosimetry of cells with a heterogeneous antigen expression and with various diameters of cells and nuclei
Radiat Res, 155 (2), 288-96
DOI 10.1667/0033-7587(2001)155[0288:rwapem]2.0.co;2, PubMed 11175663 -
Evaluation of protoporphyrin IX production, phototoxicity and cell death pathway induced by hexylester of 5-aminolevulinic acid in Reh and HPB-ALL cells
Cancer Lett, 169 (1), 33-9
DOI 10.1016/s0304-3835(01)00559-6, PubMed 11410323 -
Serial changes in tumor oxygenation during the early phase of radiation therapy in cervical cancer - Are we quantitating hypoxia change? Response
Int. J. Radiat. Oncol. Biol. Phys., 49 (1), 285-289
DOI 10.1016/S0360-3016(00)00795-1 -
Intra- and intertumor heterogeneity in blood perfusion of human cervical cancer before treatment and after radiotherapy
Int J Cancer, 96 (3), 182-90
DOI 10.1002/ijc.1019, PubMed 11410887 -
Assessment of tumor oxygenation in human cervical carcinoma by use of dynamic Gd-DTPA-enhanced MR imaging
J Magn Reson Imaging, 14 (6), 750-6
DOI 10.1002/jmri.10016, PubMed 11747032 -
The photosensitizing effect of the photoproduct of protoporphyrin IX
J Photochem Photobiol B, 60 (2-3), 108-13
DOI 10.1016/s1011-1344(01)00133-6, PubMed 11470566 -
On the pharmacokinetics of topically applied 5-aminolevulinic acid and two of its esters
Int J Cancer, 92 (1), 139-43
DOI 10.1002/1097-0215(200102)9999:9999<::aid-ijc1154>3.0.co;2-k, PubMed 11279617 -
Mechanisms and procedures in PDT
SKIN AND ENVIRONMENT - PERCEPTION AND PROTECTION, VOLS 1 AND 2, 641-647 -
On the basis for tumor selectivity in the 5-aminolevulinic acid-induced synthesis of protoporphyrin IX
J. Porphyr. Phthalocyanines, 5 (2), 170-176
DOI 10.1002/jpp.329 -
Regulation of chromosomal replication by DnaA protein availability in Escherichia coli: effects of the datA region
Biochim Biophys Acta, 1521 (1-3), 73-80
DOI 10.1016/s0167-4781(01)00292-5, PubMed 11690638 -
Microvessel oxyhemoglobin saturation does not reflect tissue oxygen tension in human melanoma xenografts
Microvasc Res, 61 (2), 199-202
DOI 10.1006/mvre.2000.2294, PubMed 11254399 -
Intratumour heterogeneity in microvessel oxyhaemoglobin saturations
Cancer Lett, 162 (2), 245-51
DOI 10.1016/s0304-3835(00)00670-4, PubMed 11146232 -
Antitumor effect of 5-aminolevulinic acid-mediated photodynamic therapy can be enhanced by the use of a low dose of photofrin in human tumor xenografts
Cancer Res, 61 (15), 5824-32
PubMed 11479222 -
Evaluation of different photosensitizers for use in photochemical gene transfection
Photochem Photobiol, 73 (4), 388-95
DOI 10.1562/0031-8655(2001)073<0388:eodpfu>2.0.co;2, PubMed 11332034 -
Thrombospondin-1-mediated metastasis suppression by the primary tumor in human melanoma xenografts
J Invest Dermatol, 117 (5), 1042-9
DOI 10.1046/j.0022-202x.2001.01552.x, PubMed 11710911 -
5-Aminolevulinic acid-based photochemical internalization of the immunotoxin MOC31-gelonin generates synergistic cytotoxic effects in vitro
Photochem Photobiol, 74 (2), 303-10
DOI 10.1562/0031-8655(2001)074<0303:aabpio>2.0.co;2, PubMed 11547569 -
In vivo documentation of photochemical internalization, a novel approach to site specific cancer therapy
Int J Cancer, 92 (5), 761-6
DOI 10.1002/1097-0215(20010601)92:5<761::aid-ijc1238>3.0.co;2-4, PubMed 11340584 -
Flow cytometers for characterization of microorganisms
Curr Protoc Cytom, Chapter 1, Unit 1.11
DOI 10.1002/0471142956.cy0111s07, PubMed 18770662 -
Staining and measurement of DNA in bacteria
Methods Cell Biol, 64, 539-51
DOI 10.1016/s0091-679x(01)64028-7, PubMed 11070854 -
Loss of chromosome 11q21-23.1 and 17p and gain of chromosome 6p are independent prognostic indicators in B-cell non-Hodgkin's lymphoma
Br J Cancer, 85 (12), 1900-13
DOI 10.1054/bjoc.2001.2164, PubMed 11747333 -
[The radiotherapy satellite in Kristiansand--a model for Norwegian regional hospitals?]
Tidsskr Nor Laegeforen, 121 (18), 2179-82
PubMed 11571996 -
Intracellular localisation of hypericin in human glioblastoma and carcinoma cell lines
Lasers Med Sci, 16 (4), 276-83
DOI 10.1007/pl00011364, PubMed 11702633 -
The influence of UV exposure on 5-aminolevulinic acid-induced protoporphyrin IX production in skin
Photochem Photobiol, 74 (6), 825-8
DOI 10.1562/0031-8655(2001)074<0825:tioueo>2.0.co;2, PubMed 11783939 -
Flow cytometric monitoring of bacterial susceptibility to antibiotics
Methods Cell Biol, 64, 553-66
DOI 10.1016/s0091-679x(01)64029-9, PubMed 11070855 -
The sequence requirements for a functional Escherichia coli replication origin are different for the chromosome and a minichromosome
Mol Microbiol, 40 (2), 498-507
DOI 10.1046/j.1365-2958.2001.02409.x, PubMed 11309131
Publications 2000
-
Exposure of human osteosarcoma and bone marrow cells to tumour-targeted alpha-particles and gamma-irradiation: analysis of cell survival and microdosimetry
Int J Radiat Biol, 76 (8), 1129-41
DOI 10.1080/09553000050111604, PubMed 10947126 -
Phototransformations of 5-aminolevulinic acid-induced protoporphyrin IX in vitro: a spectroscopic study
Photochem Photobiol, 72 (2), 186-92
DOI 10.1562/0031-8655(2000)072<0186:poaaip>2.0.co;2, PubMed 10946571 -
Measurement of the extracellular volume of human melanoma xenografts by contrast enhanced magnetic resonance imaging
Magn Reson Imaging, 18 (1), 41-8
DOI 10.1016/s0730-725x(99)00109-5, PubMed 10642101 -
Intratumor heterogeneity in perfusion in human melanoma xenografts measured by contrast-enhanced magnetic resonance imaging
Magn Reson Imaging, 18 (8), 997-1002
DOI 10.1016/s0730-725x(00)00188-0, PubMed 11121704 -
[Radiotherapy of skeletal metastases]
Tidsskr Nor Laegeforen, 120 (16), 1870-4
PubMed 10925615 -
Induction of multinucleated cells caused by UVA exposure in different stages of the cell cycle
Photochem Photobiol, 71 (5), 620-6
DOI 10.1562/0031-8655(2000)071<0620:iomccb>2.0.co;2, PubMed 10818793 -
Increased binding of chlorin e6 to lipoproteins at low pH values
Int J Biochem Cell Biol, 32 (7), 759-68
DOI 10.1016/s1357-2725(00)00015-7, PubMed 10856706 -
The bystander effect in photodynamic inactivation of cells
Biochim Biophys Acta, 1475 (3), 273-80
DOI 10.1016/s0304-4165(00)00077-5, PubMed 10913826 -
Gap junctional intercellular communication is not a major mediator in the bystander effect in photodynamic treatment of MDCK II cells
Radiat Res, 154 (3), 331-41
DOI 10.1667/0033-7587(2000)154[0331:gjicin]2.0.co;2, PubMed 10956441 -
Modeling normal tissue complication probability from repetitive computed tomography scans during fractionated high-dose-rate brachytherapy and external beam radiotherapy of the uterine cervix
Int J Radiat Oncol Biol Phys, 47 (4), 963-71
DOI 10.1016/s0360-3016(00)00510-1, PubMed 10863066 -
The constitutive level of vascular endothelial growth factor (VEGF) is more important than hypoxia-induced VEGF up-regulation in the angiogenesis of human melanoma xenografts
Br J Cancer, 82 (9), 1528-34
DOI 10.1054/bjoc.2000.1173, PubMed 10789719 -
A comparative study of normal and reverse phase high pressure liquid chromatography for analysis of porphyrins accumulated after 5-aminolaevulinic acid treatment of colon adenocarcinoma cells
Cancer Lett, 150 (2), 205-13
DOI 10.1016/s0304-3835(99)00399-7, PubMed 10704744 -
5-aminolevulinic acid induced lipid peroxidation after light exposure on human colon carcinoma cells and effects of alpha-tocopherol treatment
Cancer Lett, 159 (1), 23-32
DOI 10.1016/s0304-3835(00)00519-x, PubMed 10974402 -
Macromolecule uptake in human melanoma xenografts. relationships to blood supply, vascular density, microvessel permeability and extracellular volume fraction
Eur J Cancer, 36 (11), 1433-40
DOI 10.1016/s0959-8049(00)00120-9, PubMed 10899658 -
A fission yeast general translation factor reveals links between protein synthesis and cell cycle controls
J Cell Sci, 113 ( Pt 8), 1447-58
DOI 10.1242/jcs.113.8.1447, PubMed 10725227 -
Photochemical transfection: a new technology for light-induced, site-directed gene delivery
Hum Gene Ther, 11 (6), 869-80
DOI 10.1089/10430340050015482, PubMed 10779164 -
Quantitative determination of gap junction intercellular communication using flow cytometric measurement of fluorescent dye transfer
Cell Adhes Commun, 7 (6), 501-12
DOI 10.3109/15419060009040307, PubMed 11051460 -
Organization, chromosomal localization and promoter analysis of the gene encoding human acidic fibroblast growth factor intracellular binding protein
Biochem J, 352 Pt 3 (Pt 3), 629-35
DOI 10.1042/0264-6021:3520629, PubMed 11104667 -
Measurement of cell density and necrotic fraction in human melanoma xenografts by diffusion weighted magnetic resonance imaging
Magn Reson Med, 43 (6), 828-36
DOI 10.1002/1522-2594(200006)43:6<828::aid-mrm8>3.0.co;2-p, PubMed 10861877 -
Changes in tumor oxygen tension during radiotherapy of uterine cervical cancer: relationships to changes in vascular density, cell density, and frequency of mitosis and apoptosis
Int J Radiat Oncol Biol Phys, 46 (4), 935-46
DOI 10.1016/s0360-3016(99)00497-6, PubMed 10705016 -
Disease control of uterine cervical cancer: relationships to tumor oxygen tension, vascular density, cell density, and frequency of mitosis and apoptosis measured before treatment and during radiotherapy
Clin Cancer Res, 6 (3), 1104-12
PubMed 10741740 -
Mathematical modeling of chronical hypoxia in tumors considering potential doubling time and hypoxic cell lifetime
Radiother Oncol, 54 (2), 171-7
DOI 10.1016/s0167-8140(99)00154-1, PubMed 10699481 -
Dose distribution measurements by MRI of a phantom containing lung tissue equivalent compartments made of ferrous sulphate gel
Phys Med Biol, 45 (10), 2761-70
DOI 10.1088/0031-9155/45/10/303, PubMed 11049170 -
Role of endosomes in gene transfection mediated by photochemical internalisation (PCI)
J Gene Med, 2 (6), 477-88
DOI 10.1002/1521-2254(200011/12)2:6<477::AID-JGM137>3.0.CO;2-B, PubMed 11199268 -
Microenvironment-induced cancer metastasis
Int J Radiat Biol, 76 (5), 589-605
DOI 10.1080/095530000138259, PubMed 10866281 -
Vascular endothelial growth factor, interleukin 8, platelet-derived endothelial cell growth factor, and basic fibroblast growth factor promote angiogenesis and metastasis in human melanoma xenografts
Cancer Res, 60 (17), 4932-8
PubMed 10987309 -
Hypoxia-induced treatment failure in advanced squamous cell carcinoma of the uterine cervix is primarily due to hypoxia-induced radiation resistance rather than hypoxia-induced metastasis
Br J Cancer, 83 (3), 354-9
DOI 10.1054/bjoc.2000.1266, PubMed 10917551 -
5-aminolevulinic acid, but not 5-aminolevulinic acid esters, is transported into adenocarcinoma cells by system BETA transporters
Photochem Photobiol, 71 (5), 640-7
DOI 10.1562/0031-8655(2000)071<0640:aabnaa>2.0.co;2, PubMed 10818796 -
Release of gelonin from endosomes and lysosomes to cytosol by photochemical internalization
Biochim Biophys Acta, 1475 (3), 307-13
DOI 10.1016/s0304-4165(00)00082-9, PubMed 10913830 -
Photochemical internalisation increases the cytotoxic effect of the immunotoxin MOC31-gelonin
Int J Cancer, 87 (6), 853-9
DOI 10.1002/1097-0215(20000915)87:6<853::aid-ijc15>3.0.co;2-0, PubMed 10956397 -
Photodynamic therapy of superficial basal cell carcinoma with 5-aminolevulinic acid with dimethylsulfoxide and ethylendiaminetetraacetic acid: a comparison of two light sources
Photochem Photobiol, 71 (6), 724-9
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