Department of Immunology Publications
Publications published since 2010 from OUS - Department of Immunology (Div LabMed)
1675 publications found (only first 1000 shown)
Publications 2024
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New Insights on Genes, Gluten, and Immunopathogenesis of Celiac Disease
Gastroenterology, 167 (1), 4-22
DOI 10.1053/j.gastro.2024.03.042, PubMed 38670280 -
Ide-cel vs standard regimens in triple-class-exposed relapsed and refractory multiple myeloma: updated KarMMa-3 analyses
Blood (in press)
DOI 10.1182/blood.2024024582, PubMed 39197072 -
Why do RhD negative pregnant women still become anti-D immunized despite prophylaxis with anti-D immunoglobulin?
Transfus Apher Sci, 63 (4), 103969
DOI 10.1016/j.transci.2024.103969, PubMed 38959811 -
Vaccine responses and hybrid immunity in people living with HIV after SARS-CoV-2 breakthrough infections
NPJ Vaccines, 9 (1), 185
DOI 10.1038/s41541-024-00972-3, PubMed 39384763 -
Storage of Transfusion Platelet Concentrates Is Associated with Complement Activation and Reduced Ability of Platelets to Respond to Protease-Activated Receptor-1 and Thromboxane A2 Receptor
Int J Mol Sci, 25 (2)
DOI 10.3390/ijms25021091, PubMed 38256162 -
Systematic evaluation of B-cell clonal family inference approaches
BMC Immunol, 25 (1), 13
DOI 10.1186/s12865-024-00600-8, PubMed 38331731 -
Escalated complement activation during hospitalization is associated with higher risk of 60-day mortality in SARS-CoV-2-infected patients
J Intern Med, 296 (1), 80-92
DOI 10.1111/joim.13783, PubMed 38539241 -
Biophysical cartography of the native and human-engineered antibody landscapes quantifies the plasticity of antibody developability
Commun Biol, 7 (1), 922
DOI 10.1038/s42003-024-06561-3, PubMed 39085379 -
Biomarkers reflecting the pathogenesis, clinical manifestations, and guide therapeutic approach in systemic sclerosis: a narrative review
Clin Rheumatol, 43 (10), 3055-3072
DOI 10.1007/s10067-024-07123-y, PubMed 39210206 -
Correction: Biomarkers reflecting the pathogenesis, clinical manifestations, and guide therapeutic approach in systemic sclerosis: a narrative review
Clin Rheumatol, 43 (11), 3595
DOI 10.1007/s10067-024-07147-4, PubMed 39317835 -
MHC heterozygosity limits T cell receptor variability in CD4 T cells
Sci Immunol, 9 (97), eado5295
DOI 10.1126/sciimmunol.ado5295, PubMed 38996008 -
Acoustic Wave-Induced Stroboscopic Optical Mechanotyping of Adherent Cells
Adv Sci (Weinh), 11 (16), e2307929
DOI 10.1002/advs.202307929, PubMed 38417124 -
Barley based gluten free beer - A blessing or an uncontrollable risk?
Food Chem Toxicol, 193, 115019
DOI 10.1016/j.fct.2024.115019, PubMed 39307344 -
Development of a Smart Wireless Multisensor Platform for an Optogenetic Brain Implant
Sensors (Basel), 24 (2)
DOI 10.3390/s24020575, PubMed 38257668 -
An evaluation of diethylhexyl phthalate free top & bottom in-line blood collection set with a new soft housing filter
Transfus Med (in press)
DOI 10.1111/tme.13091, PubMed 39243178 -
Selective activation of naïve B cells with unique epitope specificity shapes autoantibody formation in celiac disease
J Autoimmun, 146, 103241
DOI 10.1016/j.jaut.2024.103241, PubMed 38754235 -
Correction to: Separate Gut Plasma Cell Populations Produce Auto-Antibodies against Transglutaminase 2 and Transglutaminase 3 in Dermatitis Herpetiformis
Adv Sci (Weinh), 11 (21), e2400894
DOI 10.1002/advs.202400894, PubMed 38477397 -
Coeliac disease as a model for understanding multiple sclerosis
Nat Rev Neurol, 20 (11), 685-690
DOI 10.1038/s41582-024-01025-y, PubMed 39379493 -
Coeliac disease: the paradox of diagnosing a food hypersensitivity disorder with autoantibodies
Gut, 73 (5), 844-853
DOI 10.1136/gutjnl-2023-331595, PubMed 38378252 -
Pertussis vaccine - pregnant women are the target group in the childhood vaccination programme
Tidsskr Nor Laegeforen, 144 (7)
DOI 10.4045/tidsskr.24.0208, PubMed 38832619 -
Current Landscape of iPSC Haplobanks
Stem Cell Rev Rep, 20 (8), 2155-2164
DOI 10.1007/s12015-024-10783-7, PubMed 39276260 -
Correction: Current Landscape of iPSC Haplobanks
Stem Cell Rev Rep (in press)
DOI 10.1007/s12015-024-10804-5, PubMed 39422809 -
The function of the complement system remains fully intact throughout the course of allogeneic stem cell transplantation
Front Immunol, 15, 1422370
DOI 10.3389/fimmu.2024.1422370, PubMed 38938578 -
The Inflammatory Response Induced by Aspergillus fumigatus Conidia Is Dependent on Complement Activation: Insight from a Whole Blood Model
J Innate Immun, 16 (1), 324-336
DOI 10.1159/000539368, PubMed 38768576 -
A novel selective leukocyte depletion human whole blood model reveals the specific roles of monocytes and granulocytes in the cytokine response to Escherichia coli
J Leukoc Biol, 115 (4), 647-663
DOI 10.1093/jleuko/qiad151, PubMed 38057165 -
The detrimental effects of intestinal injury mediated by inflammation are limited in cardiac arrest patients: A prospective cohort study
Resusc Plus, 18, 100639
DOI 10.1016/j.resplu.2024.100639, PubMed 38666252 -
Corrigendum: Experimental validation of immunogenic SARS-CoV-2 T cell epitopes identified by artificial intelligence
Front Immunol, 15, 1377041
DOI 10.3389/fimmu.2024.1377041, PubMed 38449865 -
Human IgG Fc-engineering for enhanced plasma half-life, mucosal distribution and killing of cancer cells and bacteria
Nat Commun, 15 (1), 2007
DOI 10.1038/s41467-024-46321-9, PubMed 38453922 -
Impact of the Graphene Production Methods Sonication and Microfluidization on In Vitro and In Vivo Toxicity, Macrophage Response, and Complement Activation
ACS Omega, 9 (39), 40468-40476
DOI 10.1021/acsomega.4c03189, PubMed 39372034 -
People who use drugs show no increase in pre-existing T-cell cross-reactivity toward SARS-CoV-2 but develop a normal polyfunctional T-cell response after standard mRNA vaccination
Front Immunol, 14, 1235210
DOI 10.3389/fimmu.2023.1235210, PubMed 38299149 -
B Cells With Complementary B Cell Receptors Can Kill Each Other
Eur J Immunol, e202350890 (in press)
DOI 10.1002/eji.202350890, PubMed 39520365 -
Evaluation of cerebrospinal fluid (CSF) and interstitial fluid (ISF) mouse proteomes for the validation and description of Alzheimer's disease biomarkers
J Neurosci Methods, 411, 110239
DOI 10.1016/j.jneumeth.2024.110239, PubMed 39102902 -
[A valve for maritime safety]
Tidsskr Nor Laegeforen, 144 (1)
DOI 10.4045/tidsskr.23.0767, PubMed 38258721 -
IL-22 is increased in hospitalized patients with COVID-19 and associates with cardiac involvement
J Infect, 89 (1), 106176
DOI 10.1016/j.jinf.2024.106176, PubMed 38719108 -
The effect of donation frequency on donor health in blood donors donating plasma by plasmapheresis: study protocol for a randomized controlled trial
Trials, 25 (1), 175
DOI 10.1186/s13063-024-08035-7, PubMed 38468338 -
Alternative isoform expression of key thermogenic genes in human beige adipocytes
Front Endocrinol (Lausanne), 15, 1395750
DOI 10.3389/fendo.2024.1395750, PubMed 38859907 -
[Not Available]
Tidsskr Nor Laegeforen, 144 (7)
DOI 10.4045/tidsskr.24.0136, PubMed 38832602 -
Chimeric antigen receptor T cells targeting the GM3(Neu5Gc) ganglioside
Front Immunol, 15, 1331345
DOI 10.3389/fimmu.2024.1331345, PubMed 38370401 -
Elevated NET, Calprotectin, and Neopterin Levels Discriminate between Disease Activity in COVID-19, as Evidenced by Need for Hospitalization among Patients in Northern Italy
Biomedicines, 12 (4)
DOI 10.3390/biomedicines12040766, PubMed 38672123 -
Supernumerary proteins of the human mitochondrial ribosomal small subunit are integral for assembly and translation
iScience, 27 (7), 110185
DOI 10.1016/j.isci.2024.110185, PubMed 39015150 -
Applying valency-based immuno-selection to generate broadly cross-reactive antibodies against influenza hemagglutinins
Nat Commun, 15 (1), 850
DOI 10.1038/s41467-024-44889-w, PubMed 38346952 -
Continuous germinal center invasion contributes to the diversity of the immune response
Cell, 187 (11), 2893
DOI 10.1016/j.cell.2024.04.004, PubMed 38657600 -
CD38 regulates chronic lymphocytic leukemia proliferation via CD45 phosphatase activity
Mol Ther Oncol, 32 (3), 200841
DOI 10.1016/j.omton.2024.200841, PubMed 39474602 -
Dynamic governance: A new era for consent for stem cell research
Stem Cell Reports, 19 (9), 1233-1241
DOI 10.1016/j.stemcr.2024.07.006, PubMed 39151430 -
Dissecting autoimmune encephalitis through the lens of intrathecal B cells
Proc Natl Acad Sci U S A, 121 (9), e2401337121
DOI 10.1073/pnas.2401337121, PubMed 38354256 -
Biopsy Proteome Scoring to Determine Mucosal Remodeling in Celiac Disease
Gastroenterology, 167 (3), 493-504.e10
DOI 10.1053/j.gastro.2024.03.006, PubMed 38467384 -
Biopsy Proteome Score Performs Well as an Effect Measure in a Gluten Challenge Trial of Celiac Disease
Clin Gastroenterol Hepatol (in press)
DOI 10.1016/j.cgh.2024.08.005, PubMed 39209203 -
Retraction Note: Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency
Sci Rep, 14 (1), 3704
DOI 10.1038/s41598-024-54117-6, PubMed 38355714 -
Ancestral allele of DNA polymerase gamma modifies antiviral tolerance
Nature, 628 (8009), 844-853
DOI 10.1038/s41586-024-07260-z, PubMed 38570685 -
Dynamics of SARS-CoV-2 immunity after vaccination and breakthrough infection in rituximab-treated rheumatoid arthritis patients: a prospective cohort study
Front Immunol, 15, 1296273
DOI 10.3389/fimmu.2024.1296273, PubMed 38455062 -
Krill oil supplementation in vivo promotes increased fuel metabolism and protein synthesis in cultured human skeletal muscle cells
Front Nutr, 11, 1452768
DOI 10.3389/fnut.2024.1452768, PubMed 39555189 -
Femoral Nailing in a Porcine Model Causes Bone Marrow Emboli in the Lungs and Systemic Emboli in the Heart and Brain
JB JS Open Access, 9 (1)
DOI 10.2106/JBJS.OA.23.00128, PubMed 38419616 -
Femoral nailing associated with bone marrow emboli in pigs induced a specific increase in blood IL-6 and broad inflammatory responses in the heart and lungs
Front Immunol, 15, 1396800
DOI 10.3389/fimmu.2024.1396800, PubMed 39100680 -
Benchmarking and integrating human B-cell receptor genomic and antibody proteomic profiling
NPJ Syst Biol Appl, 10 (1), 73
DOI 10.1038/s41540-024-00402-z, PubMed 38997321 -
Generation of circulating autoreactive pre-plasma cells fueled by naive B cells in celiac disease
Cell Rep, 43 (4), 114045
DOI 10.1016/j.celrep.2024.114045, PubMed 38578826 -
Aerobic adaptation and metabolic dynamics of Propionibacterium freudenreichii DSM 20271: insights from comparative transcriptomics and surfaceome analysis
mSystems, 9 (10), e0061524
DOI 10.1128/msystems.00615-24, PubMed 39345151 -
Coeliac disease in the Trøndelag Health Study (HUNT), Norway, a population-based cohort of coeliac disease patients
BMJ Open, 14 (1), e077131
DOI 10.1136/bmjopen-2023-077131, PubMed 38195172 -
The Prevalence and Rate of Undiagnosed Celiac Disease in an Adult General Population, the Trøndelag Health Study, Norway
Clin Gastroenterol Hepatol (in press)
DOI 10.1016/j.cgh.2024.06.027, PubMed 38987013 -
Gene expression analysis revealed downregulation of complement receptor 1 in clonal B cells in cold agglutinin disease
Clin Exp Immunol, 216 (1), 45-54
DOI 10.1093/cei/uxad135, PubMed 38133636 -
Corrigendum: Iatrogenic air embolism: pathoanatomy, thromboinflammation, endotheliopathy, and therapies
Front Immunol, 15, 1378003
DOI 10.3389/fimmu.2024.1378003, PubMed 38380313 -
Current status and new avenues of stem cell-based preclinical and therapeutic approaches in amyotrophic lateral sclerosis
Expert Opin Biol Ther, 24 (9), 933-954
DOI 10.1080/14712598.2024.2392307, PubMed 39162129 -
Enterocyte-Derived and Catalytically Active Transglutaminase 2 in the Gut Lumen of Mice: Implications for Celiac Disease
Gastroenterology, 167 (5), 1026-1028.e4
DOI 10.1053/j.gastro.2024.05.029, PubMed 38825048 -
Damage Control Orthopaedics Induced Less Trauma-Induced Coagulopathy than Early Total Care in a Porcine Polytrauma Model
Eur Surg Res, 65 (1), 115-122
DOI 10.1159/000541399, PubMed 39348804 -
Excessive use of preoperative blood type and antibody screening: A retrospective observational study conducted in a hospital in Norway
Acta Anaesthesiol Scand, 68 (10), 1327-1337
DOI 10.1111/aas.14493, PubMed 38981419 -
Extracellular matrix remodelling pathway in peripheral blood mononuclear cells from severe COVID-19 patients: an explorative study
Front Immunol, 15, 1379570
DOI 10.3389/fimmu.2024.1379570, PubMed 38957465 -
Universal recording of immune cell interactions in vivo
Nature, 627 (8003), 399-406
DOI 10.1038/s41586-024-07134-4, PubMed 38448581 -
The dengue-specific immune response and antibody identification with machine learning
NPJ Vaccines, 9 (1), 16
DOI 10.1038/s41541-023-00788-7, PubMed 38245547 -
Author Correction: The dengue-specific immune response and antibody identification with machine learning
NPJ Vaccines, 9 (1), 30
DOI 10.1038/s41541-024-00820-4, PubMed 38351085 -
IL-18-secreting multiantigen targeting CAR T cells eliminate antigen-low myeloma in an immunocompetent mouse model
Blood, 144 (2), 171-186
DOI 10.1182/blood.2023022293, PubMed 38579288 -
Evaluation of transfusion reactions in patients following transfusion of blood components containing antibodies to HLA class I - An attempt to prevent TRALI in patients
Transfus Apher Sci, 63 (4), 103970
DOI 10.1016/j.transci.2024.103970, PubMed 38964256 -
Cytokines in hepatitis C-infected patients with or without opioid maintenance therapy
Acta Neuropsychiatr, 1-7 (in press)
DOI 10.1017/neu.2023.56, PubMed 38173235 -
Transcriptome analysis of primary adult B-cell lineage acute lymphoblastic leukemia identifies pathogenic variants and gene fusions, and predicts subtypes for in depth molecular diagnosis
Eur J Haematol, 112 (5), 731-742
DOI 10.1111/ejh.14164, PubMed 38192186 -
Cytoskeletal rearrangement precedes nucleolar remodeling during adipogenesis
Commun Biol, 7 (1), 458
DOI 10.1038/s42003-024-06153-1, PubMed 38622242 -
Autologous Chondrocyte Implantation Is Not Better Than Arthroscopic Debridement for the Treatment of Symptomatic Cartilage Lesions of the Knee: Two-Year Results From a Randomized-Controlled Trial
Arthrosc Sports Med Rehabil, 6 (2), 100909
DOI 10.1016/j.asmr.2024.100909, PubMed 38495635 -
Insight into the avidity-affinity relationship of the bivalent, pH-dependent interaction between IgG and FcRn
MAbs, 16 (1), 2361585
DOI 10.1080/19420862.2024.2361585, PubMed 38849969 -
Gluten-Free Diet Induces Rapid Changes in Phenotype and Survival Properties of Gluten-Specific T Cells in Celiac Disease
Gastroenterology, 167 (2), 250-263
DOI 10.1053/j.gastro.2024.03.027, PubMed 38552723 -
Trauma-associated extracellular histones mediate inflammation via a MYD88-IRAK1-ERK signaling axis and induce lytic cell death in human adipocytes
Cell Death Dis, 15 (4), 285
DOI 10.1038/s41419-024-06676-9, PubMed 38653969 -
Loss of multi-level 3D genome organization during breast cancer progression
bioRxiv
DOI 10.1101/2023.11.26.568711, PubMed 38076897 -
A human autoimmune organoid model reveals IL-7 function in coeliac disease
Nature, 632 (8024), 401-410
DOI 10.1038/s41586-024-07716-2, PubMed 39048815 -
Predictability of antigen binding based on short motifs in the antibody CDRH3
Brief Bioinform, 25 (6)
DOI 10.1093/bib/bbae537, PubMed 39438077 -
Tolerance-inducing therapies in coeliac disease - mechanisms, progress and future directions
Nat Rev Gastroenterol Hepatol, 21 (5), 335-347
DOI 10.1038/s41575-024-00895-3, PubMed 38336920 -
Foetal Microchimerism Correlates With Foetal-Maternal Histocompatibility Both During Pregnancy and Postpartum
HLA, 104 (4), e15717
DOI 10.1111/tan.15717, PubMed 39435899 -
Time-dependent reduction in oxidative capacity among cultured myotubes from spinal cord injured individuals
Acta Physiol (Oxf), 240 (7), e14156
DOI 10.1111/apha.14156, PubMed 38711362 -
Type I Interferon Autoantibodies Correlate With Cellular Immune Alterations in Severe COVID-19
J Infect Dis, 230 (2), e318-e326
DOI 10.1093/infdis/jiae036, PubMed 38421006 -
ExpoSeq: simplified analysis of high-throughput sequencing data from antibody discovery campaigns
Bioinform Adv, 4 (1), vbae020
DOI 10.1093/bioadv/vbae020, PubMed 38425781 -
Engineering of pH-dependent antigen binding properties for toxin-targeting IgG1 antibodies using light-chain shuffling
Structure, 32 (9), 1404-1418.e7
DOI 10.1016/j.str.2024.07.014, PubMed 39146931 -
Characterization of the SARS-CoV-2 antibody landscape in Norway in the late summer of 2022: high seroprevalence in all age groups with patterns of primary Omicron infection in children and hybrid immunity in adults
BMC Infect Dis, 24 (1), 841
DOI 10.1186/s12879-024-09670-w, PubMed 39164637 -
NKG2A discriminates natural killer cells with a suppressed phenotype in pediatric acute leukemia
J Leukoc Biol, 115 (2), 334-343
DOI 10.1093/jleuko/qiad112, PubMed 37738462 -
No Short-Term Effect of Low-Dose Nicotine on Inflammation after Global Hypoxia in Newborn Piglets
Neonatology, 1-10 (in press)
DOI 10.1159/000541217, PubMed 39317175 -
Linguistics-based formalization of the antibody language as a basis for antibody language models
Nat Comput Sci, 4 (6), 412-422
DOI 10.1038/s43588-024-00642-3, PubMed 38877120 -
Cell identity dynamics and insight into insulin secretagogues when employing stem cell-derived islets for disease modeling
Front Bioeng Biotechnol, 12, 1392575
DOI 10.3389/fbioe.2024.1392575, PubMed 38933536 -
Glucose Concentration in Regulating Induced Pluripotent Stem Cells Differentiation Toward Insulin-Producing Cells
Transpl Int, 37, 11900
DOI 10.3389/ti.2024.11900, PubMed 38304198 -
Activation of the Innate Immune System in Brain-Dead Donors Can Be Reduced by Luminal Intestinal Preservation During Organ Procurement Surgery - A Porcine Model
Transpl Int, 37, 13569
DOI 10.3389/ti.2024.13569, PubMed 39544322 -
The effects of TGF-β-induced activation and starvation of vitamin A and palmitic acid on human stem cell-derived hepatic stellate cells
Stem Cell Res Ther, 15 (1), 223
DOI 10.1186/s13287-024-03852-8, PubMed 39044210 -
T cell responses to repeated SARS-CoV-2 vaccination and breakthrough infections in patients on TNF inhibitor treatment: a prospective cohort study
EBioMedicine, 108, 105317
DOI 10.1016/j.ebiom.2024.105317, PubMed 39260039 -
Best practices for machine learning in antibody discovery and development
Drug Discov Today, 29 (7), 104025
DOI 10.1016/j.drudis.2024.104025, PubMed 38762089 -
Seroprevalence of SARS-CoV-2 and humoral immune responses to COVID-19 mRNA vaccines among people who use drugs - in the light of tailored mitigating strategies
Harm Reduct J, 21 (1), 120
DOI 10.1186/s12954-024-01023-9, PubMed 38890611 -
Pulmonary miRNA expression after polytrauma depends on the surgical invasiveness and displays an anti-inflammatory pattern by the combined inhibition of C5 and CD14
Front Immunol, 15, 1402571
DOI 10.3389/fimmu.2024.1402571, PubMed 39267761 -
Incidence and outcome of COVID-19 following vaccine and hybrid immunity in patients on immunosuppressive therapy: identification of protective post-immunisation anti-RBD antibody levels in a prospective cohort study
RMD Open, 10 (2)
DOI 10.1136/rmdopen-2023-003545, PubMed 38599653
Publications 2023
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Adipose-Derived Stromal Cells Preserve Pancreatic Islet Function in a Transplantable 3D Bioprinted Scaffold
Adv Healthc Mater, 12 (32), e2300640
DOI 10.1002/adhm.202300640, PubMed 37781993 -
Expression of transglutaminase 2 in human gut epithelial cells: Implications for coeliac disease
PLoS One, 18 (6), e0287662
DOI 10.1371/journal.pone.0287662, PubMed 37368893 -
The neoepitope of the complement C5b-9 Membrane Attack Complex is formed by proximity of adjacent ancillary regions of C9
Commun Biol, 6 (1), 42
DOI 10.1038/s42003-023-04431-y, PubMed 36639734 -
Cellular and Genomic Features of Muscle Differentiation from Isogenic Fibroblasts and Myoblasts
Cells, 12 (15)
DOI 10.3390/cells12151995, PubMed 37566074 -
A pan-SARS-CoV-2-specific soluble angiotensin-converting enzyme 2-albumin fusion engineered for enhanced plasma half-life and needle-free mucosal delivery
PNAS Nexus, 2 (12), pgad403
DOI 10.1093/pnasnexus/pgad403, PubMed 38077689 -
Wnt/β-Catenin Signaling Activation Induces Differentiation in Human Limbal Epithelial Stem Cells Cultured Ex Vivo
Biomedicines, 11 (7)
DOI 10.3390/biomedicines11071829, PubMed 37509479 -
Dual inhibition of complement C5 and CD14 attenuates inflammation in a cord blood model
Pediatr Res, 94 (2), 512-519
DOI 10.1038/s41390-023-02489-2, PubMed 36725909 -
HLA-DQ2 is associated with anti-drug antibody formation to infliximab in patients with immune-mediated inflammatory diseases
J Intern Med, 293 (5), 648-655
DOI 10.1111/joim.13616, PubMed 36843323 -
Neisseria meningitidis accumulate in large organs during meningococcal sepsis
Front Cell Infect Microbiol, 13, 1298360
DOI 10.3389/fcimb.2023.1298360, PubMed 38089821 -
Pump-less, recirculating organ-on-a-chip (rOoC) platform
Lab Chip, 23 (4), 591-608
DOI 10.1039/d2lc00919f, PubMed 36655405 -
Escherichia coli-induced inflammatory responses are temperature-dependent in human whole blood ex vivo
Mol Immunol, 157, 70-77
DOI 10.1016/j.molimm.2023.03.006, PubMed 37001293 -
Identification of gluten T cell epitopes driving celiac disease
Sci Adv, 9 (4), eade5800
DOI 10.1126/sciadv.ade5800, PubMed 36696493 -
Lipopolysaccharide Primes Human Macrophages for Noncanonical Inflammasome-Induced Extracellular Vesicle Secretion
J Immunol, 210 (3), 322-334
DOI 10.4049/jimmunol.2200444, PubMed 36525001 -
Functional Analysis of a Novel Complement C5a Receptor 1-Blocking Monoclonal Antibody
J Innate Immun, 15 (1), 836-849
DOI 10.1159/000535084, PubMed 37952515 -
Bacterial Brain Abscesses Expand Despite Effective Antibiotic Treatment: A Process Powered by Osmosis Due to Neutrophil Cell Death
Neurosurgery, 94 (5), 1079-87 (in press)
DOI 10.1227/neu.0000000000002792, PubMed 38084989 -
Separate Gut Plasma Cell Populations Produce Auto-Antibodies against Transglutaminase 2 and Transglutaminase 3 in Dermatitis Herpetiformis
Adv Sci (Weinh), 10 (25), e2300401
DOI 10.1002/advs.202300401, PubMed 37424036 -
XCR1+ DCs are critical for T cell-mediated immunotherapy of chronic viral infections
Cell Rep, 42 (2), 112123
DOI 10.1016/j.celrep.2023.112123, PubMed 36795562 -
Scandiatransplant Exchange Program (STEP): Development and Results From an International Kidney Exchange Program
Transplant Direct, 9 (11), e1549
DOI 10.1097/TXD.0000000000001549, PubMed 37854025 -
Application and challenges of TCR and BCR sequencing to investigate T- and B-cell clonality in elastase-induced experimental murine abdominal aortic aneurysm
Front Cardiovasc Med, 10, 1221620
DOI 10.3389/fcvm.2023.1221620, PubMed 38034381 -
[Post-vaccination observation time should not be halved]
Tidsskr Nor Laegeforen, 143 (8)
DOI 10.4045/tidsskr.23.0327, PubMed 37254986 -
DNase analysed by a novel competitive assay in patients with complications after ChAdOx1 nCoV-19 vaccination and in normal unvaccinated blood donors
Scand J Immunol, 98 (1), e13274
DOI 10.1111/sji.13274, PubMed 37676118 -
Experimental validation of immunogenic SARS-CoV-2 T cell epitopes identified by artificial intelligence
Front Immunol, 14, 1265044
DOI 10.3389/fimmu.2023.1265044, PubMed 38045681 -
Robust spike-specific CD4+ and CD8+ T cell responses in SARS-CoV-2 vaccinated hematopoietic cell transplantation recipients: a prospective, cohort study
Front Immunol, 14, 1210899
DOI 10.3389/fimmu.2023.1210899, PubMed 37503339 -
Assessing developability early in the discovery process for novel biologics
MAbs, 15 (1), 2171248
DOI 10.1080/19420862.2023.2171248, PubMed 36823021 -
Rapid, Cost-Efficient, Enzyme-Free Passaging of Human Pluripotent Stem Cells on Feeder Cells by Ethylenediaminetetraacetic Acid-Mediated Dis-Adhesion
J Vis Exp (197)
DOI 10.3791/63788, PubMed 37486113 -
A systematic safety pipeline for selection of T-cell receptors to enter clinical use
NPJ Vaccines, 8 (1), 126
DOI 10.1038/s41541-023-00713-y, PubMed 37607971 -
PML modulates epigenetic composition of chromatin to regulate expression of pro-metastatic genes in triple-negative breast cancer
Nucleic Acids Res, 51 (20), 11024-11039
DOI 10.1093/nar/gkad819, PubMed 37823593 -
Comparison between articular chondrocytes and mesenchymal stromal cells for the production of articular cartilage implants
Front Bioeng Biotechnol, 11, 1116513
DOI 10.3389/fbioe.2023.1116513, PubMed 36896010 -
Ocrelizumab and ofatumumab, but not rituximab, trigger complement induction in vitro
Int Immunopharmacol, 124 (Pt B), 111021
DOI 10.1016/j.intimp.2023.111021, PubMed 37816262 -
In vitro evaluation of iron oxide nanoparticle-induced thromboinflammatory response using a combined human whole blood and endothelial cell model
Front Immunol, 14, 1101387
DOI 10.3389/fimmu.2023.1101387, PubMed 37081885 -
Antibody blockade of Jagged1 attenuates choroidal neovascularization
Nat Commun, 14 (1), 3109
DOI 10.1038/s41467-023-38563-w, PubMed 37253747 -
Progressive mitochondrial dysfunction in cerebellar synaptosomes of cystatin B-deficient mice
Front Mol Neurosci, 16, 1175851
DOI 10.3389/fnmol.2023.1175851, PubMed 37251643 -
The expanding family of T follicular regulatory cells
Sci Immunol, 8 (82), eadg7526
DOI 10.1126/sciimmunol.adg7526, PubMed 37027479 -
Increased thromboinflammatory load in hereditary angioedema
Clin Exp Immunol, 214 (2), 170-181
DOI 10.1093/cei/uxad091, PubMed 37561062 -
High plasma levels of C1-inhibitor are associated with lower risk of future venous thromboembolism
J Thromb Haemost, 21 (7), 1849-1860
DOI 10.1016/j.jtha.2023.03.024, PubMed 37003465 -
In vitro and ex vivo proteomics of Mycobacterium marinum biofilms and the development of biofilm-binding synthetic nanobodies
mSystems, 8 (3), e0107322
DOI 10.1128/msystems.01073-22, PubMed 37184670 -
Scalable production of tissue-like vascularized liver organoids from human PSCs
Exp Mol Med, 55 (9), 2005-2024
DOI 10.1038/s12276-023-01074-1, PubMed 37653039 -
Autoantibody binding and unique enzyme-substrate intermediate conformation of human transglutaminase 3
Nat Commun, 14 (1), 6216
DOI 10.1038/s41467-023-42004-z, PubMed 37798283 -
Human thymic putative CD8αα precursors exhibit a biased TCR repertoire in single cell AIRR-seq
Sci Rep, 13 (1), 17714
DOI 10.1038/s41598-023-44693-4, PubMed 37853083 -
Systemic inflammation early after kidney transplantation is associated with long-term graft loss: a cohort study
Front Immunol, 14, 1253991
DOI 10.3389/fimmu.2023.1253991, PubMed 37849758 -
A tumor microenvironment model of chronic lymphocytic leukemia enables drug sensitivity testing to guide precision medicine
Cell Death Discov, 9 (1), 125
DOI 10.1038/s41420-023-01426-w, PubMed 37055391 -
A man in his seventies with fatigue and renal failure
Tidsskr Nor Laegeforen, 143 (9)
DOI 10.4045/tidsskr.22.0679, PubMed 37341412 -
Editorial: Organ cross talk and its impact on the clinical course in multiple trauma and critical illness
Front Immunol, 14, 1195371
DOI 10.3389/fimmu.2023.1195371, PubMed 37090701 -
Humoral vaccine response and breakthrough infections in kidney transplant recipients during the COVID-19 pandemic: a nationwide cohort study
EClinicalMedicine, 60, 102035
DOI 10.1016/j.eclinm.2023.102035, PubMed 37362086 -
Functional SARS-CoV-2 cross-reactive CD4+ T cells established in early childhood decline with age
Proc Natl Acad Sci U S A, 120 (12), e2220320120
DOI 10.1073/pnas.2220320120, PubMed 36917669 -
Tracking the cellular immune response from early premalignancy to active multiple myeloma in a new model
Eur J Immunol, 54 (1), e2350627
DOI 10.1002/eji.202350627, PubMed 37872778 -
Safe Blood Donation from Donors Using Antihypertensive Medication. A Multi-Center Retrospective Quality Study from South-East Norway
J Blood Med, 14, 337-343
DOI 10.2147/JBM.S390609, PubMed 37163174 -
Humoral immune response to SARS-CoV-2 vaccination in patients with inflammatory bowel disease on immunosuppressive medication: association to serum drug levels and disease type
Scand J Gastroenterol, 58 (8), 874-882
DOI 10.1080/00365521.2023.2177884, PubMed 36788656 -
Pharmaceutical compounding and storage of faricimab in a syringe for intravitreal injection do not impair stability and bi-specific binding properties
Int J Retina Vitreous, 9 (1), 65
DOI 10.1186/s40942-023-00507-3, PubMed 37936232 -
Towards optimised extracellular vesicle proteomics from cerebrospinal fluid
Sci Rep, 13 (1), 9564
DOI 10.1038/s41598-023-36706-z, PubMed 37308520 -
Hybrid and SARS-CoV-2-vaccine immunity in kidney transplant recipients
EBioMedicine, 97, 104833
DOI 10.1016/j.ebiom.2023.104833, PubMed 37844534 -
Toward real-world automated antibody design with combinatorial Bayesian optimization
Cell Rep Methods, 3 (1), 100374
DOI 10.1016/j.crmeth.2022.100374, PubMed 36814835 -
EMD originates from hyaluronan-induced homophilic interactions of CD44 variant-expressing MM cells under shear stress
Blood Adv, 7 (4), 508-524
DOI 10.1182/bloodadvances.2022007291, PubMed 35930695 -
Kidney-transplanted Adolescents-Nonadherence and Graft Outcomes During the Transition Phase: A Nationwide Analysis, 2000-2020
Transplantation, 107 (5), 1206-1212
DOI 10.1097/TP.0000000000004431, PubMed 36476728 -
Vasa, Piwi, and Pl10 Expression during Sexual Maturation and Asexual Reproduction in the Annelid Pristina longiseta
J Dev Biol, 11 (3)
DOI 10.3390/jdb11030034, PubMed 37606490 -
SENP2 knockdown in human adipocytes reduces glucose metabolism and lipid accumulation, while increases lipid oxidation
Metabol Open, 18, 100234
DOI 10.1016/j.metop.2023.100234, PubMed 37013149 -
Characterization of Mechanical and Cellular Effects of Rhythmic Vertical Vibrations on Adherent Cell Cultures
Bioengineering (Basel), 10 (7)
DOI 10.3390/bioengineering10070811, PubMed 37508838 -
Mass spectrometry reveals that oxysterols are secreted from non-alcoholic fatty liver disease induced organoids
J Steroid Biochem Mol Biol, 232, 106355
DOI 10.1016/j.jsbmb.2023.106355, PubMed 37380087 -
Quantitative chemometric phenotyping of three-dimensional liver organoids by Raman spectral imaging
Cell Rep Methods, 3 (4), 100440
DOI 10.1016/j.crmeth.2023.100440, PubMed 37159662 -
[When peril is greatest]
Tidsskr Nor Laegeforen, 143 (11)
DOI 10.4045/tidsskr.23.0379, PubMed 37589349 -
A strong case for third-party testing
Elife, 12
DOI 10.7554/eLife.93329, PubMed 37962204 -
Interplay between Cultured Human Osteoblastic and Skeletal Muscle Cells: Effects of Conditioned Media on Glucose and Fatty Acid Metabolism
Biomedicines, 11 (11)
DOI 10.3390/biomedicines11112908, PubMed 38001909 -
Disruption of the sialic acid/Siglec-9 axis improves antibody-mediated neutrophil cytotoxicity towards tumor cells
Front Immunol, 14, 1178817
DOI 10.3389/fimmu.2023.1178817, PubMed 37346044 -
[ARDS or acute respiratory failure syndrome?]
Tidsskr Nor Laegeforen, 143 (10)
DOI 10.4045/tidsskr.23.0402, PubMed 37376931 -
Gene Regulatory Interactions at Lamina-Associated Domains
Genes (Basel), 14 (2)
DOI 10.3390/genes14020334, PubMed 36833261 -
Assessing IgE sensitization profiles to birch and timothy grass pollen allergens in birch pollen allergic blood donors using an oligoplex specific IgE assay
Scand J Clin Lab Invest, 83 (7), 444-447
DOI 10.1080/00365513.2023.2255972, PubMed 37737679 -
Iatrogenic air embolism: pathoanatomy, thromboinflammation, endotheliopathy, and therapies
Front Immunol, 14, 1230049
DOI 10.3389/fimmu.2023.1230049, PubMed 37795086 -
Preclinical Evaluation of a 64Cu-Based Theranostic Approach in a Murine Model of Multiple Myeloma
Pharmaceutics, 15 (7)
DOI 10.3390/pharmaceutics15071817, PubMed 37514004 -
Prevalent and immunodominant CD8 T cell epitopes are conserved in SARS-CoV-2 variants
Cell Rep, 42 (1), 111995
DOI 10.1016/j.celrep.2023.111995, PubMed 36656713 -
Effects of storage on quality and function of acid-treated platelets with reduced HLA Class I surface expression
Transfus Med, 33 (4), 329-336
DOI 10.1111/tme.12983, PubMed 37356816 -
A homozygous POLR1A variant causes leukodystrophy and affects protein homeostasis
Brain, 146 (8), 3513-3527
DOI 10.1093/brain/awad086, PubMed 36917474 -
Cytosolic antibody receptor TRIM21 is required for effective tau immunotherapy in mouse models
Science, 379 (6639), 1336-1341
DOI 10.1126/science.abn1366, PubMed 36996217 -
Circulating markers of extracellular matrix remodelling in severe COVID-19 patients
J Intern Med, 294 (6), 784-797
DOI 10.1111/joim.13725, PubMed 37718572 -
H2S-Enriched Flush out Does Not Increase Donor Organ Quality in a Porcine Kidney Perfusion Model
Antioxidants (Basel), 12 (3)
DOI 10.3390/antiox12030749, PubMed 36978997 -
Quartz Crystal Microbalance Platform for SARS-CoV-2 Immuno-Diagnostics
Int J Mol Sci, 24 (23)
DOI 10.3390/ijms242316705, PubMed 38069027 -
Efforts to recruit and enhance blood donor return probability: A point of view from Oslo, Norway
Transfus Apher Sci, 62 (4), 103760
DOI 10.1016/j.transci.2023.103760, PubMed 37453908 -
COVID-19 patients treated with convalescent plasma
Tidsskr Nor Laegeforen, 143 (11)
DOI 10.4045/tidsskr.22.0577, PubMed 37589359 -
Convalescent plasma from Norwegian blood donors to treat COVID-19
Tidsskr Nor Laegeforen, 143 (11)
DOI 10.4045/tidsskr.22.0180, PubMed 37589362 -
Characterizations of a neutralizing antibody broadly reactive to multiple gluten peptide:HLA-DQ2.5 complexes in the context of celiac disease
Nat Commun, 14 (1), 8502
DOI 10.1038/s41467-023-44083-4, PubMed 38135691 -
Simultaneous LC-MS determination of glucose regulatory peptides secreted by stem cell-derived islet organoids
Electrophoresis, 44 (21-22), 1682-1697
DOI 10.1002/elps.202300095, PubMed 37574258 -
Single-cell transcriptomics combined with proteomics of intrathecal IgG reveal transcriptional heterogeneity of oligoclonal IgG-secreting cells in multiple sclerosis
Front Cell Neurosci, 17, 1189709
DOI 10.3389/fncel.2023.1189709, PubMed 37362001 -
Defining and Studying B Cell Receptor and TCR Interactions
J Immunol, 211 (3), 311-322
DOI 10.4049/jimmunol.2300136, PubMed 37459189 -
Determinants of humoral and cellular immune responses to three doses of mRNA SARS-CoV-2 vaccines in older adults: a longitudinal cohort study
Lancet Healthy Longev, 4 (5), e188-e199
DOI 10.1016/S2666-7568(23)00055-7, PubMed 37148891 -
Safety of hypoxic red blood cell administration in patients with transfusion-dependent hematological malignancies: An interim analysis
Transfus Apher Sci, 62 (5), 103755
DOI 10.1016/j.transci.2023.103755, PubMed 37423867 -
Active maintenance of CD8+ T cell naivety through regulation of global genome architecture
Cell Rep, 42 (10), 113301
DOI 10.1016/j.celrep.2023.113301, PubMed 37858463 -
Active maintenance of CD8+ T cell naïvety through regulation of global genome architecture
bioRxiv
DOI 10.1101/2023.02.26.530139, PubMed 36909629 -
Local Postoperative Graft Inflammation in Pancreas Transplant Patients With Early Graft Thrombosis
Transplant Direct, 10 (1), e1567
DOI 10.1097/TXD.0000000000001567, PubMed 38094132 -
Thromboinflammatory response is increased in pancreas transplant alone versus simultaneous pancreas-kidney transplantation and early pancreas graft thrombosis is associated with complement activation
Front Immunol, 14, 1044444
DOI 10.3389/fimmu.2023.1044444, PubMed 37063904 -
Small extracellular vesicles have distinct CD81 and CD9 tetraspanin expression profiles in plasma from rheumatoid arthritis patients
Clin Exp Med, 23 (6), 2867-2875
DOI 10.1007/s10238-023-01024-1, PubMed 36826611 -
Identifying a core protein signature of small extracellular vesicles derived from B-cell precursor acute lymphoblastic leukaemia
Scand J Immunol, 99 (3), e13341
DOI 10.1111/sji.13341, PubMed 38441169 -
Plasma Inflammatory Biomarkers Are Associated With Poststroke Cognitive Impairment: The Nor-COAST Study
Stroke, 54 (5), 1303-1311
DOI 10.1161/STROKEAHA.122.041965, PubMed 37026459 -
Prevalence and Characteristics Associated With Post-COVID-19 Condition Among Nonhospitalized Adolescents and Young Adults
JAMA Netw Open, 6 (3), e235763
DOI 10.1001/jamanetworkopen.2023.5763, PubMed 36995712 -
Predicting the immune escape of SARS-CoV-2 neutralizing antibodies upon mutation
Biochim Biophys Acta Mol Basis Dis, 1870 (2), 166959
DOI 10.1016/j.bbadis.2023.166959, PubMed 37967796 -
A role for the terminal C5-C9 complement pathway in idiopathic pulmonary fibrosis
Front Med (Lausanne), 10, 1236495
DOI 10.3389/fmed.2023.1236495, PubMed 37621463 -
Complement factors B, D, C3bBbP and risk of future venous thromboembolism
Clin Immunol, 249, 109278
DOI 10.1016/j.clim.2023.109278, PubMed 36894046 -
Transdiagnostic Associations between Anger Hostility and Chemokine Interferon-gamma Inducible Protein 10
Clin Psychopharmacol Neurosci, 22 (2), 285-294
DOI 10.9758/cpn.23.1091, PubMed 38627075 -
Inflammatory markers and pulmonary function in adolescents and young adults 6 months after mild COVID-19
Front Immunol, 13, 1081718
DOI 10.3389/fimmu.2022.1081718, PubMed 36685555 -
Terminating Routine Cord Blood RhD Typing of the Newborns to Guide Postnatal Anti-D Immunoglobulin Prophylaxis Based on the Results of Fetal RHD Genotyping
Fetal Diagn Ther, 50 (4), 276-281
DOI 10.1159/000531694, PubMed 37379821 -
Effect of Intraperitoneal 224Radium-Labelled Microparticles on Compartmentalized Inflammation After Cytoreductive Surgery and Hypertherm Intraperitoneal Chemotherapy
Technol Cancer Res Treat, 22, 15330338231192902
DOI 10.1177/15330338231192902, PubMed 37574949 -
Design and preclinical testing of an anti-CD41 CAR T cell for the treatment of acute megakaryoblastic leukaemia
J Cell Mol Med, 27 (19), 2864-2875
DOI 10.1111/jcmm.17810, PubMed 37667538 -
RNA sequencing suggests that non-coding RNAs play a role in the development of acquired haemophilia
J Cell Mol Med, 27 (13), 1790-1796
DOI 10.1111/jcmm.17741, PubMed 37317065 -
Pathology and Molecular Biology of Melanoma
Curr Issues Mol Biol, 45 (7), 5575-5597
DOI 10.3390/cimb45070352, PubMed 37504268 -
Management of Wrong Blood Transfusion to an RhD Negative Woman in Labor
Int J Womens Health, 15, 1-6
DOI 10.2147/IJWH.S390661, PubMed 36628052 -
Trimeric, APC-Targeted Subunit Vaccines Protect Mice against Seasonal and Pandemic Influenza
J Virol, 97 (2), e0169422
DOI 10.1128/jvi.01694-22, PubMed 36719241 -
Author Correction: Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants
NPJ Vaccines, 8 (1), 4
DOI 10.1038/s41541-023-00600-6, PubMed 36697432 -
Efficacy and safety of baricitinib in hospitalized adults with severe or critical COVID-19 (Bari-SolidAct): a randomised, double-blind, placebo-controlled phase 3 trial
Crit Care, 27 (1), 9
DOI 10.1186/s13054-022-04205-8, PubMed 36627655 -
A Mouse Model for the Rapid and Binomial Assessment of Putative WNT/β-Catenin Signalling Inhibitors
Biomedicines, 11 (10)
DOI 10.3390/biomedicines11102719, PubMed 37893093 -
Phage display assisted discovery of a pH-dependent anti-α-cobratoxin antibody from a natural variable domain library
Protein Sci, 32 (12), e4821
DOI 10.1002/pro.4821, PubMed 37897425 -
Coagulopathy and adverse outcomes in hospitalized patients with COVID-19: results from the NOR-Solidarity trial
Res Pract Thromb Haemost, 8 (1), 102289
DOI 10.1016/j.rpth.2023.102289, PubMed 38292350 -
Low-density lipoprotein particles carrying proinflammatory proteins with altered aggregation pattern detected in COVID-19 patients 3 months after hospitalization
J Infect, 86 (5), 489-492
DOI 10.1016/j.jinf.2023.02.024, PubMed 36822413 -
Increased muscle activity during sleep and more RBD symptoms in H1N1-(Pandemrix)-vaccinated narcolepsy type 1 patients compared with their non-narcoleptic siblings
Sleep, 46 (3)
DOI 10.1093/sleep/zsac316, PubMed 36562330 -
Pediatric glioma histone H3.3 K27M/G34R mutations drive abnormalities in PML nuclear bodies
Genome Biol, 24 (1), 284
DOI 10.1186/s13059-023-03122-5, PubMed 38066546 -
Liquid Biopsy in Organ Damage: small extracellular vesicle chip-based assessment of polytrauma
Front Immunol, 14, 1279496
DOI 10.3389/fimmu.2023.1279496, PubMed 38035093 -
Neuraminidase delivered as an APC-targeted DNA vaccine induces protective antibodies against influenza
Mol Ther, 31 (7), 2188-2205
DOI 10.1016/j.ymthe.2023.03.012, PubMed 36926694 -
Id-neoantigen vaccine induces therapeutic CD8+ T cells against multiple myeloma: H chain-loss escapees cause FLC MM
J Immunother Cancer, 11 (8)
DOI 10.1136/jitc-2023-006944, PubMed 37607769 -
Characterization of human stem cell-derived hepatic stellate cells and liver sinusoidal endothelial cells during extended in vitro culture
Front Bioeng Biotechnol, 11, 1223737
DOI 10.3389/fbioe.2023.1223737, PubMed 37560536 -
T cell responses to SARS-CoV-2 vaccination differ by disease-modifying therapy for multiple sclerosis
JCI Insight, 8 (12)
DOI 10.1172/jci.insight.165111, PubMed 37159281 -
Distinct microRNA and protein profiles of extracellular vesicles secreted from myotubes from morbidly obese donors with type 2 diabetes in response to electrical pulse stimulation
Front Physiol, 14, 1143966
DOI 10.3389/fphys.2023.1143966, PubMed 37064893 -
Humoral Response After 6 or More Successive Doses of SARS-CoV-2 mRNA Vaccines in Kidney Transplant Recipients-Should We Keep Vaccinating?
Transplantation, 107 (10), e279-e280
DOI 10.1097/TP.0000000000004732, PubMed 37496122
Publications 2022
-
Progress and challenges for the machine learning-based design of fit-for-purpose monoclonal antibodies
MAbs, 14 (1), 2008790
DOI 10.1080/19420862.2021.2008790, PubMed 35293269 -
In silico proof of principle of machine learning-based antibody design at unconstrained scale
MAbs, 14 (1), 2031482
DOI 10.1080/19420862.2022.2031482, PubMed 35377271 -
Machine learning and molecular simulation ascertain antimicrobial peptide against Klebsiella pneumoniae from public database
Comput Biol Chem, 102, 107800
DOI 10.1016/j.compbiolchem.2022.107800, PubMed 36516617 -
Transglutaminase 2 affinity and enzyme-substrate intermediate stability as determining factors for T-cell responses to gluten peptides in celiac disease
Eur J Immunol, 52 (9), 1474-1481
DOI 10.1002/eji.202249862, PubMed 35715890 -
Seroprevalence of antibodies against SARS-CoV-2 in the adult population during the pre-vaccination period, Norway, winter 2020/21
Euro Surveill, 27 (13)
DOI 10.2807/1560-7917.ES.2022.27.13.2100376, PubMed 35362405 -
The Effect of Aerobic Exercise and Low-Impact Pilates Workout on the Adaptive Immune System
J Clin Med, 11 (22)
DOI 10.3390/jcm11226814, PubMed 36431291 -
Neoantigen vaccine-induced CD4 T cells confer protective immunity in a mouse model of multiple myeloma through activation of CD8 T cells against non-vaccine, tumor-associated antigens
J Immunother Cancer, 10 (2)
DOI 10.1136/jitc-2021-003572, PubMed 35190376 -
Restructuring of Lamina-Associated Domains in Senescence and Cancer
Cells, 11 (11)
DOI 10.3390/cells11111846, PubMed 35681541 -
Four SARS-CoV-2 vaccine doses or hybrid immunity in patients on immunosuppressive therapies: a Norwegian cohort study
Lancet Rheumatol, 5 (1), e36-e46
DOI 10.1016/S2665-9913(22)00330-7, PubMed 36415604 -
Chasing neoantigens; invite naïve T cells to the party
Curr Opin Immunol, 75, 102172
DOI 10.1016/j.coi.2022.102172, PubMed 35279483 -
Pitfalls in complement analysis: A systematic literature review of assessing complement activation
Front Immunol, 13, 1007102
DOI 10.3389/fimmu.2022.1007102, PubMed 36330514 -
The Tankyrase Inhibitor OM-153 Demonstrates Antitumor Efficacy and a Therapeutic Window in Mouse Models
Cancer Res Commun, 2 (4), 233-245
DOI 10.1158/2767-9764.CRC-22-0027, PubMed 36873622 -
Effects of organic chemicals from diesel exhaust particles on adipocytes differentiated from human mesenchymal stem cells
Basic Clin Pharmacol Toxicol, 132 (1), 83-97
DOI 10.1111/bcpt.13805, PubMed 36214226 -
Prevention of covid-19 and other acute respiratory infections with cod liver oil supplementation, a low dose vitamin D supplement: quadruple blinded, randomised placebo controlled trial
BMJ, 378, e071245
DOI 10.1136/bmj-2022-071245, PubMed 36215222 -
Transcriptomic changes in the large organs in lethal meningococcal shock are reflected in a porcine shock model
Front Cell Infect Microbiol, 12, 908204
DOI 10.3389/fcimb.2022.908204, PubMed 36034711 -
C-reactive protein levels and depression in older and younger adults - A study of 19,947 individuals. The Tromsø study
Brain Behav Immun Health, 27, 100571
DOI 10.1016/j.bbih.2022.100571, PubMed 36583067 -
Academic User View: Organ-on-a-Chip Technology
Biosensors (Basel), 12 (2)
DOI 10.3390/bios12020126, PubMed 35200386 -
The persistence of anti-Spike antibodies following two SARS-CoV-2 vaccine doses in patients on immunosuppressive therapy compared to healthy controls-a prospective cohort study
BMC Med, 20 (1), 378
DOI 10.1186/s12916-022-02587-8, PubMed 36199139 -
Phenotype-Based Isolation of Antigen-Specific CD4+ T Cells in Autoimmunity: A Study of Celiac Disease
Adv Sci (Weinh), 9 (10), e2104766
DOI 10.1002/advs.202104766, PubMed 35119226 -
Pathogenic T Cells in Celiac Disease Change Phenotype on Gluten Challenge: Implications for T-Cell-Directed Therapies
Adv Sci (Weinh), 9 (34), e2205912
DOI 10.1002/advs.202205912, PubMed 36482157 -
Structural basis of T cell receptor specificity and cross-reactivity of two HLA-DQ2.5-restricted gluten epitopes in celiac disease
J Biol Chem, 298 (3), 101619
DOI 10.1016/j.jbc.2022.101619, PubMed 35065967 -
TCRpower: quantifying the detection power of T-cell receptor sequencing with a novel computational pipeline calibrated by spike-in sequences
Brief Bioinform, 23 (2)
DOI 10.1093/bib/bbab566, PubMed 35062022 -
Glioblastoma microenvironment contains multiple hormonal and non-hormonal growth-stimulating factors
Fluids Barriers CNS, 19 (1), 45
DOI 10.1186/s12987-022-00333-z, PubMed 35659255 -
High Levels of Complement Activating Enzyme MASP-2 Are Associated With the Risk of Future Incident Venous Thromboembolism
Arterioscler Thromb Vasc Biol, 42 (9), 1186-1197
DOI 10.1161/ATVBAHA.122.317746, PubMed 35861070 -
Synthetic Oligodeoxynucleotide CpG Motifs Activate Human Complement through Their Backbone Structure and Induce Complement-Dependent Cytokine Release
J Immunol, 209 (9), 1760-1767
DOI 10.4049/jimmunol.2101191, PubMed 36104112 -
Target organ expression and biomarker characterization of chemokine CCL21 in systemic sclerosis associated pulmonary arterial hypertension
Front Immunol, 13, 991743
DOI 10.3389/fimmu.2022.991743, PubMed 36211384 -
Development of a High-Affinity Antibody against the Tumor-Specific and Hyperactive 611-p95HER2 Isoform
Cancers (Basel), 14 (19)
DOI 10.3390/cancers14194859, PubMed 36230782 -
Tetraspanin CD53 controls T cell immunity through regulation of CD45RO stability, mobility, and function
Cell Rep, 39 (13), 111006
DOI 10.1016/j.celrep.2022.111006, PubMed 35767951 -
Blood Transcriptome Analysis of Septic Patients Reveals a Long Non-Coding Alu-RNA in the Complement C5a Receptor 1 Gene
Noncoding RNA, 8 (2)
DOI 10.3390/ncrna8020024, PubMed 35447887 -
Potent TRIM21 and complement-dependent intracellular antiviral immunity requires the IgG3 hinge
Sci Immunol, 7 (70), eabj1640
DOI 10.1126/sciimmunol.abj1640, PubMed 35486676 -
Raised Serum Markers of T Cell Activation and Exhaustion in Granulomatous-Lymphocytic Interstitial Lung Disease in Common Variable Immunodeficiency
J Clin Immunol, 42 (7), 1553-1563
DOI 10.1007/s10875-022-01318-1, PubMed 35789314 -
Affinity maturation of TCR-like antibodies using phage display guided by structural modeling
Protein Eng Des Sel, 35
DOI 10.1093/protein/gzac005, PubMed 35871543 -
Heme Interferes With Complement Factor I-Dependent Regulation by Enhancing Alternative Pathway Activation
Front Immunol, 13, 901876
DOI 10.3389/fimmu.2022.901876, PubMed 35935964 -
Ex vivo drug sensitivity screening in multiple myeloma identifies drug combinations that act synergistically
Mol Oncol, 16 (6), 1241-1258
DOI 10.1002/1878-0261.13191, PubMed 35148457 -
Biophysical differences in IgG1 Fc-based therapeutics relate to their cellular handling, interaction with FcRn and plasma half-life
Commun Biol, 5 (1), 832
DOI 10.1038/s42003-022-03787-x, PubMed 35982144 -
A Silicone Oil-Free Syringe Tailored for Intravitreal Injection of Biologics
Front Ophthalmol (Lausanne), 2, 882013
DOI 10.3389/fopht.2022.882013, PubMed 38983507 -
Molecular mechanisms governing development of the hindbrain choroid plexus and auditory projection: A validation of the seminal observations of Wilhelm His
IBRO Neurosci Rep, 13, 306-313
DOI 10.1016/j.ibneur.2022.09.011, PubMed 36247525 -
Omicron Variant Generates a Higher and More Sustained Viral Load in Nasopharynx and Saliva Than the Delta Variant of SARS-CoV-2
Viruses, 14 (11)
DOI 10.3390/v14112420, PubMed 36366518 -
CXCL16 associates with adverse outcome and cardiac involvement in hospitalized patients with Covid-19
J Infect, 85 (6), 702-769
DOI 10.1016/j.jinf.2022.09.029, PubMed 36216188 -
What are the current driving questions in immune repertoire research?
Cell Syst, 13 (9), 683-686
DOI 10.1016/j.cels.2022.08.006, PubMed 36137509 -
Antibody variable sequences have a pronounced effect on cellular transport and plasma half-life
iScience, 25 (2), 103746
DOI 10.1016/j.isci.2022.103746, PubMed 35118359 -
Single-Cell Analysis and Tracking of Antigen-Specific T Cells: Integrating Paired Chain AIRR-Seq and Transcriptome Sequencing: A Method by the AIRR Community
Methods Mol Biol, 2453, 379-421
DOI 10.1007/978-1-0716-2115-8_20, PubMed 35622336 -
Inflammatory Markers and Radiotherapy Response in Patients With Painful Bone Metastases
J Pain Symptom Manage, 64 (4), 330-339
DOI 10.1016/j.jpainsymman.2022.06.018, PubMed 35803553 -
[J.M. Haga responds]
Tidsskr Nor Laegeforen, 142 (4)
DOI 10.4045/tidsskr.22.0108, PubMed 35239273 -
Genetic association study in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) identifies several potential risk loci
Brain Behav Immun, 102, 362-369
DOI 10.1016/j.bbi.2022.03.010, PubMed 35318112 -
International guidelines regarding the role of intravenous immunoglobulin in the management of RhD- and ABO-mediated haemolytic disease of the newborn-reconsidering the recommendations
Br J Haematol, 199 (3), 452-453
DOI 10.1111/bjh.18421, PubMed 35993219 -
Allele imputation for the killer cell immunoglobulin-like receptor KIR3DL1/S1
PLoS Comput Biol, 18 (2), e1009059
DOI 10.1371/journal.pcbi.1009059, PubMed 35192601 -
Label-free quantitative proteomics and immunoblotting identifies immunoreactive and other excretory-secretory (E/S) proteins of Anoplocephala perfoliata
Front Immunol, 13, 1045468
DOI 10.3389/fimmu.2022.1045468, PubMed 36466892 -
Inflammation in the early phase after kidney transplantation is associated with increased long-term all-cause mortality
Am J Transplant, 22 (8), 2016-2027
DOI 10.1111/ajt.17047, PubMed 35352462 -
COVID-19 convalescent plasma: current status, lessons from the past and future perspectives
Transfus Apher Sci, 61 (4), 103487
DOI 10.1016/j.transci.2022.103487, PubMed 35778352 -
Inflammatory markers calprotectin, NETs, syndecan-1 and neopterin in COVID-19 convalescent blood donors
Scand J Clin Lab Invest, 82 (6), 481-485
DOI 10.1080/00365513.2022.2123387, PubMed 36151851 -
Elevated NETs and Calprotectin Levels after ChAdOx1 nCoV-19 Vaccination Correlate with the Severity of Side Effects
Vaccines (Basel), 10 (8)
DOI 10.3390/vaccines10081267, PubMed 36016155 -
Antigen bivalency of antigen-presenting cell-targeted vaccines increases B cell responses
Cell Rep, 39 (9), 110901
DOI 10.1016/j.celrep.2022.110901, PubMed 35649357 -
Clozapine Reverses Dysfunction of Glutamatergic Neurons Derived From Clozapine-Responsive Schizophrenia Patients
Front Cell Neurosci, 16, 830757
DOI 10.3389/fncel.2022.830757, PubMed 35281293 -
Interleukin-6 inhibition in ST-elevation myocardial infarction: Immune cell profile in the randomised ASSAIL-MI trial
EBioMedicine, 80, 104013
DOI 10.1016/j.ebiom.2022.104013, PubMed 35504178 -
Mechanism of CD79A and CD79B Support for IgM+ B Cell Fitness through B Cell Receptor Surface Expression
J Immunol, 209 (10), 2042-2053
DOI 10.4049/jimmunol.2200144, PubMed 36426942 -
T cell receptor repertoire sequencing reveals chemotherapy-driven clonal expansion in colorectal liver metastases
Gigascience, 12
DOI 10.1093/gigascience/giad032, PubMed 37161965 -
Clinical characteristics and proteome modifications in two Charcot-Marie-Tooth families with the AARS1 Arg326Trp mutation
BMC Neurol, 22 (1), 299
DOI 10.1186/s12883-022-02828-6, PubMed 35971119 -
Immune responses to SARS-CoV-2 vaccines in celiac disease
Scand J Gastroenterol, 58 (2), 142-147
DOI 10.1080/00365521.2022.2114809, PubMed 36049123 -
T-helper cell regulation of CD45 phosphatase activity by galectin-1 and CD43 governs chronic lymphocytic leukaemia proliferation
Br J Haematol, 198 (3), 556-573
DOI 10.1111/bjh.18285, PubMed 35655388 -
The Immunobiology and Pathogenesis of Celiac Disease
Annu Rev Pathol, 18, 47-70
DOI 10.1146/annurev-pathmechdis-031521-032634, PubMed 36067801 -
Complement Is Activated During Normothermic Machine Perfusion of Porcine and Human Discarded Kidneys
Front Immunol, 13, 831371
DOI 10.3389/fimmu.2022.831371, PubMed 35911712 -
Thrombin Differentially Modulates the Acute Inflammatory Response to Escherichia coli and Staphylococcus aureus in Human Whole Blood
J Immunol, 208 (12), 2771-2778
DOI 10.4049/jimmunol.2101033, PubMed 35675954 -
VSIG4-expressing tumor-associated macrophages impair anti-tumor immunity
Biochem Biophys Res Commun, 628, 18-24
DOI 10.1016/j.bbrc.2022.08.055, PubMed 36063598 -
Profiling the baseline performance and limits of machine learning models for adaptive immune receptor repertoire classification
Gigascience, 11
DOI 10.1093/gigascience/giac046, PubMed 35639633 -
simAIRR: simulation of adaptive immune repertoires with realistic receptor sequence sharing for benchmarking of immune state prediction methods
Gigascience, 12
DOI 10.1093/gigascience/giad074, PubMed 37848619 -
Immune responses in Omicron SARS-CoV-2 breakthrough infection in vaccinated adults
Nat Commun, 13 (1), 4165
DOI 10.1038/s41467-022-31888-y, PubMed 35851055 -
The Highly Productive Thermothelomyces heterothallica C1 Expression System as a Host for Rapid Development of Influenza Vaccines
Vaccines (Basel), 10 (2)
DOI 10.3390/vaccines10020148, PubMed 35214607 -
[More children should receive the influenza vaccine]
Tidsskr Nor Laegeforen, 142 (17)
DOI 10.4045/tidsskr.22.0678, PubMed 36416658 -
"Organ-in-a-Column" Coupled On-line with Liquid Chromatography-Mass Spectrometry
Anal Chem, 94 (50), 17677-17684
DOI 10.1021/acs.analchem.2c04530, PubMed 36484723 -
A trio of biological rhythms and their relevance in rhythmic mechanical stimulation of cell cultures
Front Psychol, 13, 867191
DOI 10.3389/fpsyg.2022.867191, PubMed 35967633 -
Immunogenicity and Safety of a Third SARS-CoV-2 Vaccine Dose in Patients With Multiple Sclerosis and Weak Immune Response After COVID-19 Vaccination
JAMA Neurol, 79 (3), 307-309
DOI 10.1001/jamaneurol.2021.5109, PubMed 35072702 -
Complement C3b contributes to Escherichia coli-induced platelet aggregation in human whole blood
Front Immunol, 13, 1020712
DOI 10.3389/fimmu.2022.1020712, PubMed 36591264 -
EWAS of post-COVID-19 patients shows methylation differences in the immune-response associated gene, IFI44L, three months after COVID-19 infection
Sci Rep, 12 (1), 11478
DOI 10.1038/s41598-022-15467-1, PubMed 35798818 -
Identification of Novel Loci Shared by Juvenile Idiopathic Arthritis Subtypes Through Integrative Genetic Analysis
Arthritis Rheumatol, 74 (8), 1420-1429
DOI 10.1002/art.42129, PubMed 35347896 -
KIR+CD8+ T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19
Science, 376 (6590), eabi9591
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Stereotyped B-cell responses are linked to IgG constant region polymorphisms in multiple sclerosis
Eur J Immunol, 52 (4), 550-565
DOI 10.1002/eji.202149576, PubMed 35094395 -
Injection of prototypic celiac anti-transglutaminase 2 antibodies in mice does not cause enteropathy
PLoS One, 17 (4), e0266543
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Multiple Myeloma-Derived Extracellular Vesicles Modulate the Bone Marrow Immune Microenvironment
Front Immunol, 13, 909880
DOI 10.3389/fimmu.2022.909880, PubMed 35874665 -
Inflammatory Markers, Pulmonary Function, and Clinical Symptoms in Acute COVID-19 Among Non-Hospitalized Adolescents and Young Adults
Front Immunol, 13, 837288
DOI 10.3389/fimmu.2022.837288, PubMed 35222429 -
Simultaneous C5 and CD14 inhibition limits inflammation and organ dysfunction in pig polytrauma
Front Immunol, 13, 952267
DOI 10.3389/fimmu.2022.952267, PubMed 36059503 -
Local euchromatin enrichment in lamina-associated domains anticipates their repositioning in the adipogenic lineage
Genome Biol, 23 (1), 91
DOI 10.1186/s13059-022-02662-6, PubMed 35410387 -
Biology and Model Predictions of the Dynamics and Heterogeneity of Chromatin-Nuclear Lamina Interactions
Front Cell Dev Biol, 10, 913458
DOI 10.3389/fcell.2022.913458, PubMed 35693945 -
[Menstrual abnormalities after COVID-19 vaccination]
Tidsskr Nor Laegeforen, 142 (9)
DOI 10.4045/tidsskr.22.0217, PubMed 35699538 -
Adaptive Immune Receptor Repertoire (AIRR) Community Guide to Repertoire Analysis
Methods Mol Biol, 2453, 297-316
DOI 10.1007/978-1-0716-2115-8_17, PubMed 35622333 -
Single-cell BCR and transcriptome analysis after influenza infection reveals spatiotemporal dynamics of antigen-specific B cells
Cell Rep, 41 (9), 111764
DOI 10.1016/j.celrep.2022.111764, PubMed 36450255 -
Vitamin C, Hydrocortisone, and the Combination Thereof Significantly Inhibited Two of Nine Inflammatory Markers Induced by Escherichia Coli But Not by Staphylococcus Aureus - When Incubated in Human Whole Blood
Shock, 57 (1), 72-80
DOI 10.1097/SHK.0000000000001834, PubMed 34265830 -
Insight Into the Metabolic Adaptations of Electrically Pulse-Stimulated Human Myotubes Using Global Analysis of the Transcriptome and Proteome
Front Physiol, 13, 928195
DOI 10.3389/fphys.2022.928195, PubMed 35874526 -
Complement activation predicts negative outcomes in COVID-19: The experience from Northen Italian patients
Autoimmun Rev, 22 (1), 103232
DOI 10.1016/j.autrev.2022.103232, PubMed 36414219 -
Fourth dose of the SARS-CoV-2 vaccine in kidney transplant recipients with previously impaired humoral antibody response
Am J Transplant, 22 (11), 2704-2706
DOI 10.1111/ajt.17091, PubMed 35533010 -
Application of the C3 inhibitor compstatin in a human whole blood model designed for complement research - 20 years of experience and future perspectives
Semin Immunol, 59, 101604
DOI 10.1016/j.smim.2022.101604, PubMed 35570131 -
Proceedings of the annual meeting of the European Consortium of Lipodystrophies (ECLip) Cambridge, UK, 7-8 April 2022
Ann Endocrinol (Paris), 83 (6), 461-468
DOI 10.1016/j.ando.2022.07.674, PubMed 36206842 -
Remdesivir modifies interferon response in hospitalized COVID-19 patients
J Infect, 85 (5), 573-607
DOI 10.1016/j.jinf.2022.07.021, PubMed 35914611 -
Prevention of Fetal/Neonatal Alloimmune Thrombocytopenia in Mice: Biochemical and Cell Biological Characterization of Isoforms of a Human Monoclonal Antibody
Immunohorizons, 6 (1), 90-103
DOI 10.4049/immunohorizons.2100097, PubMed 35074850 -
Antirheumatic therapy is associated with reduced complement activation in rheumatoid arthritis
PLoS One, 17 (2), e0264628
DOI 10.1371/journal.pone.0264628, PubMed 35213675 -
A Novel Porcine Model of Ischemia-Reperfusion Injury After Cross-Clamping the Thoracic Aorta Revealed Substantial Cardiopulmonary, Thromboinflammatory and Biochemical Changes Without Effect of C1-Inhibitor Treatment
Front Immunol, 13, 852119
DOI 10.3389/fimmu.2022.852119, PubMed 35432333 -
Screening for antibodies to HLA class I in apheresis donors following Covid-19 or SARS-CoV-2 vaccination
Transfus Apher Sci, 61 (5), 103567
DOI 10.1016/j.transci.2022.103567, PubMed 36089469 -
[Blood and emergency preparedness]
Tidsskr Nor Laegeforen, 142 (11)
DOI 10.4045/tidsskr.22.0494, PubMed 35997179 -
COVID-19 convalescent plasma from Norwegian blood donors
Tidsskr Nor Laegeforen, 142 (9)
DOI 10.4045/tidsskr.22.0057, PubMed 35699539 -
Modeling the 3D Genome Using Hi-C and Nuclear Lamin-Genome Contacts
Methods Mol Biol, 2301, 337-352
DOI 10.1007/978-1-0716-1390-0_18, PubMed 34415545 -
The evolutionary and functional significance of germline immunoglobulin gene variation
Trends Immunol, 44 (1), 7-21
DOI 10.1016/j.it.2022.11.001, PubMed 36470826 -
Apyrase-mediated amplification of secretory IgA promotes intestinal homeostasis
Cell Rep, 40 (3), 111112
DOI 10.1016/j.celrep.2022.111112, PubMed 35858559 -
Long non-coding RNA HOTAIR regulates cytoskeleton remodeling and lipid storage capacity during adipogenesis
Sci Rep, 12 (1), 10157
DOI 10.1038/s41598-022-14296-6, PubMed 35710716 -
De novo annotation of lncRNA HOTAIR transcripts by long-read RNA capture-seq reveals a differentiation-driven isoform switch
BMC Genomics, 23 (1), 658
DOI 10.1186/s12864-022-08887-w, PubMed 36115964 -
Platelet-Depletion of Whole Blood Reveals That Platelets Potentiate the Release of IL-8 From Leukocytes Into Plasma in a Thrombin-Dependent Manner
Front Immunol, 13, 865386
DOI 10.3389/fimmu.2022.865386, PubMed 35444648 -
Rituximab-treated patients with lymphoma develop strong CD8 T-cell responses following COVID-19 vaccination
Br J Haematol, 197 (6), 697-708
DOI 10.1111/bjh.18149, PubMed 35254660 -
Phenotypic Analysis of Disease-Relevant T Cells in Dermatitis Herpetiformis
J Invest Dermatol, 143 (1), 163-166.e2
DOI 10.1016/j.jid.2022.07.007, PubMed 35961617 -
Unconstrained generation of synthetic antibody-antigen structures to guide machine learning methodology for antibody specificity prediction
Nat Comput Sci, 2 (12), 845-865
DOI 10.1038/s43588-022-00372-4, PubMed 38177393 -
CompAIRR: ultra-fast comparison of adaptive immune receptor repertoires by exact and approximate sequence matching
Bioinformatics, 38 (17), 4230-4232
DOI 10.1093/bioinformatics/btac505, PubMed 35852318 -
Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset
Ann Rheum Dis, 81 (8), 1085-1095
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Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer
Breast Cancer Res, 24 (1), 52
DOI 10.1186/s13058-022-01547-7, PubMed 35850772 -
Contribution of the ex vivo placental perfusion model in understanding transplacental immunoglobulin G transfer
Placenta, 127, 77-87
DOI 10.1016/j.placenta.2022.07.019, PubMed 35981406 -
Access to ground truth at unconstrained size makes simulated data as indispensable as experimental data for bioinformatics methods development and benchmarking
Bioinformatics, 38 (21), 4994-4996
DOI 10.1093/bioinformatics/btac612, PubMed 36073940 -
Molecular fate-mapping of serum antibodies reveals the effects of antigenic imprinting on repeated immunization
bioRxiv
DOI 10.1101/2022.08.29.505743, PubMed 36093344 -
Vaccine associated benign headache and cutaneous hemorrhage after ChAdOx1 nCoV-19 vaccine: A cohort study
J Stroke Cerebrovasc Dis, 32 (1), 106860
DOI 10.1016/j.jstrokecerebrovasdis.2022.106860, PubMed 36403363 -
Markers of extracellular matrix remodeling and systemic inflammation in patients with heritable thoracic aortic diseases
Front Cardiovasc Med, 9, 1073069
DOI 10.3389/fcvm.2022.1073069, PubMed 36606286 -
Functional testing of relapsed chronic lymphocytic leukemia guides precision medicine and maps response and resistance mechanisms. An index case
Haematologica, 107 (8), 1994-1998
DOI 10.3324/haematol.2021.280393, PubMed 35236056 -
Epstein-Barr virus as a driver of multiple sclerosis
Sci Immunol, 7 (70), eabo7799
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Tango of B cells with T cells in the making of secretory antibodies to gut bacteria
Nat Rev Gastroenterol Hepatol, 20 (2), 120-128
DOI 10.1038/s41575-022-00674-y, PubMed 36056203 -
Association between brain-derived neurotropic factor (BDNF), high-sensitivity C-reactive protein (hs-CRP) and psychiatric symptoms in medicated and unmedicated patients
BMC Psychiatry, 22 (1), 84
DOI 10.1186/s12888-022-03744-2, PubMed 35114967 -
Dental and Periodontal Health in Acute Intermittent Porphyria
Life (Basel), 12 (8)
DOI 10.3390/life12081270, PubMed 36013449 -
Venous Air Embolism Activates Complement C3 Without Corresponding C5 Activation and Trigger Thromboinflammation in Pigs
Front Immunol, 13, 839632
DOI 10.3389/fimmu.2022.839632, PubMed 35371063 -
Immunogenicity and safety of a three-dose SARS-CoV-2 vaccination strategy in patients with immune-mediated inflammatory diseases on immunosuppressive therapy
RMD Open, 8 (2)
DOI 10.1136/rmdopen-2022-002417, PubMed 36328399 -
Immunogenicity and Safety of Standard and Third-Dose SARS-CoV-2 Vaccination in Patients Receiving Immunosuppressive Therapy
Arthritis Rheumatol, 74 (8), 1321-1332
DOI 10.1002/art.42153, PubMed 35507355 -
Following targeted routine antenatal anti-D prophylaxis, almost half of the pregnant women had undetectable anti-D prophylaxis at delivery
Acta Obstet Gynecol Scand, 101 (4), 431-440
DOI 10.1111/aogs.14328, PubMed 35224728 -
Breakthrough infections with the omicron and delta variants of SARS-CoV-2 result in similar re-activation of vaccine-induced immunity
Front Immunol, 13, 964525
DOI 10.3389/fimmu.2022.964525, PubMed 36159859 -
Corticosteroids and superinfections in COVID-19 patients on invasive mechanical ventilation
J Infect, 85 (1), 57-63
DOI 10.1016/j.jinf.2022.05.015, PubMed 35605805 -
Targeting Xcr1 on Dendritic Cells Rapidly Induce Th1-Associated Immune Responses That Contribute to Protection Against Influenza Infection
Front Immunol, 13, 752714
DOI 10.3389/fimmu.2022.752714, PubMed 35296089 -
Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants
NPJ Vaccines, 7 (1), 174
DOI 10.1038/s41541-022-00586-7, PubMed 36585405 -
Persistent T-cell exhaustion in relation to prolonged pulmonary pathology and death after severe COVID-19: Results from two Norwegian cohort studies
J Intern Med, 292 (5), 816-828
DOI 10.1111/joim.13549, PubMed 35982589 -
Prevalence of antibodies against SARS-CoV-2 in the Norwegian population, August 2021
Influenza Other Respir Viruses, 16 (6), 1004-1013
DOI 10.1111/irv.13024, PubMed 35770841 -
High Circulating Levels of the Homeostatic Chemokines CCL19 and CCL21 Predict Mortality and Disease Severity in COVID-19
J Infect Dis, 226 (12), 2150-2160
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Histone H3.3 phosphorylation promotes heterochromatin formation by inhibiting H3K9/K36 histone demethylase
Nucleic Acids Res, 50 (8), 4500-4514
DOI 10.1093/nar/gkac259, PubMed 35451487 -
No replication of previously reported association with genetic variants in the T cell receptor alpha (TRA) locus for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)
Transl Psychiatry, 12 (1), 277
DOI 10.1038/s41398-022-02046-1, PubMed 35821115 -
Anti-PF4/polyanion antibodies in COVID-19 patients are associated with disease severity and pulmonary pathology
Platelets, 33 (4), 640-644
DOI 10.1080/09537104.2022.2042238, PubMed 35225150 -
[Efficacy of three doses of COVID-19 vaccine]
Tidsskr Nor Laegeforen, 142 (5)
DOI 10.4045/tidsskr.22.0096, PubMed 35324133 -
Globally Accessible Distributed Data Sharing (GADDS): a decentralized FAIR platform to facilitate data sharing in the life sciences
Bioinformatics, 38 (15), 3812-3817
DOI 10.1093/bioinformatics/btac362, PubMed 35639939 -
Respiratory dysfunction three months after severe COVID-19 is associated with gut microbiota alterations
J Intern Med, 291 (6), 801-812
DOI 10.1111/joim.13458, PubMed 35212063 -
Generation of Multivalent Nanobody-Based Proteins with Improved Neutralization of Long α-Neurotoxins from Elapid Snakes
Bioconjug Chem, 33 (8), 1494-1504
DOI 10.1021/acs.bioconjchem.2c00220, PubMed 35875886 -
Clinical Significance of Serum Albumin and Implications of FcRn Inhibitor Treatment in IgG-Mediated Autoimmune Disorders
Front Immunol, 13, 892534
DOI 10.3389/fimmu.2022.892534, PubMed 35757719 -
Reference-based comparison of adaptive immune receptor repertoires
Cell Rep Methods, 2 (8), 100269
DOI 10.1016/j.crmeth.2022.100269, PubMed 36046619 -
Scandiatransplant acceptable mismatch program-10 years with an effective strategy for transplanting highly sensitized patients
Am J Transplant, 22 (12), 2869-2879
DOI 10.1111/ajt.17182, PubMed 36030513 -
Machine-designed biotherapeutics: opportunities, feasibility and advantages of deep learning in computational antibody discovery
Brief Bioinform, 23 (4)
DOI 10.1093/bib/bbac267, PubMed 35830864 -
Associations between cardiac and pulmonary involvement in patients with juvenile dermatomyositis-a cross-sectional study
Rheumatol Int, 42 (7), 1213-1220
DOI 10.1007/s00296-021-05071-3, PubMed 34984516 -
Stabilization of Keratinocyte Monolayer Integrity in the Presence of Anti-Desmoglein-3 Antibodies through FcRn Blockade with Efgartigimod: Novel Treatment Paradigm for Pemphigus?
Cells, 11 (6)
DOI 10.3390/cells11060942, PubMed 35326398 -
Correction: Zakrzewicz et al. Stabilization of Keratinocyte Monolayer Integrity in the Presence of Anti-Desmoglein-3 Antibodies through FcRn Blockade with Efgartigimod: Novel Treatment Paradigm for Pemphigus? Cells 2022, 11, 942
Cells, 11 (10)
DOI 10.3390/cells11101700, PubMed 35626757 -
Focused B cell response to recurring gluten motif with implications for epitope spreading in celiac disease
Cell Rep, 41 (4), 111541
DOI 10.1016/j.celrep.2022.111541, PubMed 36288703 -
Isolation of a cytolytic subpopulation of extracellular vesicles derived from NK cells containing NKG7 and cytolytic proteins
Front Immunol, 13, 977353
DOI 10.3389/fimmu.2022.977353, PubMed 36189227
Publications 2021
-
Transcriptome analysis reveals disparate expression of inflammation-related miRNAs and their gene targets in iPSC-astrocytes from people with schizophrenia
Brain Behav Immun, 94, 235-244
DOI 10.1016/j.bbi.2021.01.037, PubMed 33571628 -
Extensive downregulation of immune gene expression by microRNA-140-3p 5' isomiR in an in vitro model of osteoarthritis
Osteoarthr Cartil Open, 3 (3), 100189
DOI 10.1016/j.ocarto.2021.100189, PubMed 36474808 -
International Forum on the Collection and Use of COVID-19 Convalescent Plasma: Protocols, Challenges and Lessons Learned: Summary
Vox Sang, 116 (10), 1117-1135
DOI 10.1111/vox.13113, PubMed 34013968 -
International Forum on the Collection and Use of COVID-19 Convalescent Plasma: Responses
Vox Sang, 116 (10), e71-e120
DOI 10.1111/vox.13114, PubMed 34013981 -
Investigating novel biomarkers of immune activation and modulation in the context of sedentary behaviour: a multicentre prospective ischemic stroke cohort study
BMC Neurol, 21 (1), 318
DOI 10.1186/s12883-021-02343-0, PubMed 34399717 -
Neopterin and kynurenic acid as predictors of stroke recurrence and mortality: a multicentre prospective cohort study on biomarkers of inflammation measured three months after ischemic stroke
BMC Neurol, 21 (1), 476
DOI 10.1186/s12883-021-02498-w, PubMed 34879833 -
Pandemic Preparedness Against Influenza: DNA Vaccine for Rapid Relief
Front Immunol, 12, 747032
DOI 10.3389/fimmu.2021.747032, PubMed 34691056 -
[The vaccines can keep up with the SARS-CoV-2 mutations]
Tidsskr Nor Laegeforen, 141 (3)
DOI 10.4045/tidsskr.21.0080, PubMed 33624975 -
The lytic polysaccharide monooxygenase CbpD promotes Pseudomonas aeruginosa virulence in systemic infection
Nat Commun, 12 (1), 1230
DOI 10.1038/s41467-021-21473-0, PubMed 33623002 -
The potential of porcine ex vivo platform for intestinal permeability screening of FcRn-targeted drugs
Eur J Pharm Biopharm, 162, 99-104
DOI 10.1016/j.ejpb.2021.03.009, PubMed 33771621 -
Prevention of diabetes-associated fibrosis: Strategies in FcRn-targeted nanosystems for oral drug delivery
Adv Drug Deliv Rev, 175, 113778
DOI 10.1016/j.addr.2021.04.016, PubMed 33887405 -
Potential impact of celiac disease genetic risk factors on T cell receptor signaling in gluten-specific CD4+ T cells
Sci Rep, 11 (1), 9252
DOI 10.1038/s41598-021-86612-5, PubMed 33927210 -
Evaluation of the Effects of Remdesivir and Hydroxychloroquine on Viral Clearance in COVID-19 : A Randomized Trial
Ann Intern Med, 174 (9), 1261-1269
DOI 10.7326/M21-0653, PubMed 34251903 -
Irradiation to prevent a fatal transfusion complication
Tidsskr. Nor. Laegeforen., 141 (9), 828-831 -
APC-Targeted DNA Vaccination Against Reticulocyte-Binding Protein Homolog 5 Induces Plasmodium falciparum-Specific Neutralizing Antibodies and T Cell Responses
Front Immunol, 12, 720550
DOI 10.3389/fimmu.2021.720550, PubMed 34733274 -
[Glomerulonephritis after contact with a horse]
Tidsskr Nor Laegeforen, 141 (4)
DOI 10.4045/tidsskr.20.0780, PubMed 33685097 -
Physical constraints in polymer modeling of chromatin associations with the nuclear periphery at kilobase scale
Nucleus, 12 (1), 6-20
DOI 10.1080/19491034.2020.1868105, PubMed 33435761 -
Thermoplastic Elastomer (TPE)-Poly(Methyl Methacrylate) (PMMA) Hybrid Devices for Active Pumping PDMS-Free Organ-on-a-Chip Systems
Biosensors (Basel), 11 (5)
DOI 10.3390/bios11050162, PubMed 34069506 -
Complement activation is associated with poor outcome after out-of-hospital cardiac arrest
Resuscitation, 166, 129-136
DOI 10.1016/j.resuscitation.2021.05.038, PubMed 34126135 -
Nicotinamide Riboside and Metformin Ameliorate Mitophagy Defect in Induced Pluripotent Stem Cell-Derived Astrocytes With POLG Mutations
Front Cell Dev Biol, 9, 737304
DOI 10.3389/fcell.2021.737304, PubMed 34631714 -
Pathogenic T Cells in Celiac Disease Change Phenotype on Gluten Challenge: Implications for T-Cell-Directed Therapies
Adv Sci (Weinh), 8 (21), e2102778
DOI 10.1002/advs.202102778, PubMed 34495570 -
Targeting the Notch Signaling Pathway in Chronic Inflammatory Diseases
Front Immunol, 12, 668207
DOI 10.3389/fimmu.2021.668207, PubMed 33912195 -
Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease
Genome Biol, 22 (1), 198
DOI 10.1186/s13059-021-02413-z, PubMed 34229738 -
Recommendation for validation and quality assurance of non-invasive prenatal testing for foetal blood groups and implications for IVD risk classification according to EU regulations
Vox Sang, 117 (2), 157-165
DOI 10.1111/vox.13172, PubMed 34155647 -
3D Printed Tooling for Injection Molded Microfluidics
Macromol. Mater. Eng., 306 (11), 2100464
DOI 10.1002/mame.202100464 -
Next-Generation Sequencing Identifies Extended HLA Class I and II Haplotypes Associated With Early-Onset and Late-Onset Myasthenia Gravis in Italian, Norwegian, and Swedish Populations
Front Immunol, 12, 667336
DOI 10.3389/fimmu.2021.667336, PubMed 34163474 -
Comprehensive Analysis of CDR3 Sequences in Gluten-Specific T-Cell Receptors Reveals a Dominant R-Motif and Several New Minor Motifs
Front Immunol, 12, 639672
DOI 10.3389/fimmu.2021.639672, PubMed 33927715 -
Hemorrhagic Shock Induces a Rapid Transcriptomic Shift of the Immune Balance in Leukocytes after Experimental Multiple Injury
Mediators Inflamm, 2021, 6654318
DOI 10.1155/2021/6654318, PubMed 33574730 -
Generation of an HLA-DQ2.5 Knock-In Mouse
Immunohorizons, 5 (1), 25-32
DOI 10.4049/immunohorizons.2000107, PubMed 33461981 -
Single-cell TCR repertoire analysis reveals highly polyclonal composition of human intraepithelial CD8+ αβ T lymphocytes in untreated celiac disease
Eur J Immunol, 51 (6), 1542-1545
DOI 10.1002/eji.202048974, PubMed 33559929 -
Lasting Immunological Imprint of Primary Epstein-Barr Virus Infection With Associations to Chronic Low-Grade Inflammation and Fatigue
Front Immunol, 12, 715102
DOI 10.3389/fimmu.2021.715102, PubMed 34987499 -
Scaffold-Free Engineering of Human Cartilage Implants
Cartilage, 13 (1_suppl), 1237S-1249S
DOI 10.1177/19476035211007923, PubMed 33858229 -
A high-affinity human TCR-like antibody detects celiac disease gluten peptide-MHC complexes and inhibits T cell activation
Sci Immunol, 6 (62)
DOI 10.1126/sciimmunol.abg4925, PubMed 34417258 -
Alloimmunization in transfused patients with constitutional anemias in Norway
Transfus Apher Sci, 60 (5), 103257
DOI 10.1016/j.transci.2021.103257, PubMed 34420880 -
Therapeutic Targeting of the Complement System: From Rare Diseases to Pandemics
Pharmacol Rev, 73 (2), 792-827
DOI 10.1124/pharmrev.120.000072, PubMed 33687995 -
Correction to: In vivo Cell Tracking Using Non-invasive Imaging of Iron Oxide-Based Particles with Particular Relevance for Stem Cell-Based Treatments of Neurological and Cardiac Disease
Mol Imaging Biol, 23 (4), 624
DOI 10.1007/s11307-021-01590-4, PubMed 34131884 -
International Forum on Mitigation Strategies to Prevent Faint and Pre-faint Adverse Reactions in Whole Blood Donors: Responses
Vox Sang, 116 (3), e1-e24
DOI 10.1111/vox.13038, PubMed 33754360 -
Impact of a Vancomycin-Induced Shift of the Gut Microbiome in a Gram-Negative Direction on Plasma Factor VIII:C Levels: Results from a Randomized Controlled Trial
Thromb Haemost, 122 (4), 540-551
DOI 10.1055/s-0041-1733906, PubMed 34428832 -
[Norway – the maritime nation that lets people drown]
Tidsskr Nor Laegeforen, 141 (2021-12)
DOI 10.4045/tidsskr.21.0568, PubMed 34505473 -
Fine mapping of the major histocompatibility complex (MHC) in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) suggests involvement of both HLA class I and class II loci
Brain Behav Immun, 98, 101-109
DOI 10.1016/j.bbi.2021.08.219, PubMed 34403736 -
[Strange statement about diagnoses]
Tidsskr Nor Laegeforen, 141 (3)
DOI 10.4045/tidsskr.21.0081, PubMed 33624973 -
MicroRNAs mediated regulation of glutathione peroxidase 7 expression and its changes during adipogenesis
Biochim Biophys Acta Gene Regul Mech, 1864 (10), 194734
DOI 10.1016/j.bbagrm.2021.194734, PubMed 34339889 -
Liver Organoids: Recent Developments, Limitations and Potential
Front Med (Lausanne), 8, 574047
DOI 10.3389/fmed.2021.574047, PubMed 34026769 -
ARHGAP45 controls naïve T- and B-cell entry into lymph nodes and T-cell progenitor thymus seeding
EMBO Rep, 22 (4), e52196
DOI 10.15252/embr.202052196, PubMed 33719206 -
Covid-19 transmission in fitness centers in Norway - a randomized trial
BMC Public Health, 21 (1), 2103
DOI 10.1186/s12889-021-12073-0, PubMed 34789188 -
Immune complexes, innate immunity, and NETosis in ChAdOx1 vaccine-induced thrombocytopenia
Eur Heart J, 42 (39), 4064-4072
DOI 10.1093/eurheartj/ehab506, PubMed 34405870 -
The Alternative Complement Pathway Is Activated Without a Corresponding Terminal Pathway Activation in Patients With Heart Failure
Front Immunol, 12, 800978
DOI 10.3389/fimmu.2021.800978, PubMed 35003128 -
Ancestral diversity is limited in published T cell receptor sequencing studies
Immunity, 54 (10), 2177-2179
DOI 10.1016/j.immuni.2021.09.015, PubMed 34644550 -
Sero-prevalence of SARS-CoV-2 antibodies in blood donors during the third wave of infection in Norway, winter/spring 2021
Transfus Apher Sci, 60 (5), 103256
DOI 10.1016/j.transci.2021.103256, PubMed 34420881 -
Acrodermatitis chronica atrophicans in prolonged borrelia infection
Tidsskr Nor Laegeforen, 141 (16)
DOI 10.4045/tidsskr.21.0201, PubMed 34758594 -
Antibody-mediated delivery of T-cell epitopes to antigen-presenting cells induce strong CD4 and CD8 T-cell responses
Vaccine, 39 (11), 1583-1592
DOI 10.1016/j.vaccine.2021.02.012, PubMed 33612340 -
An mRNA SARS-CoV-2 vaccine employing Charge-Altering Releasable Transporters with a TLR-9 agonist induces neutralizing antibodies and T cell memory
bioRxiv
DOI 10.1101/2021.04.14.439891, PubMed 33880472 -
Combined blockade of complement C5 and TLR co-receptor CD14 synergistically inhibits pig-to-human corneal xenograft induced innate inflammatory responses
Acta Biomater, 127, 169-179
DOI 10.1016/j.actbio.2021.03.047, PubMed 33785451 -
The blood transcriptome prior to ovarian cancer diagnosis: A case-control study in the NOWAC postgenome cohort
PLoS One, 16 (8), e0256442
DOI 10.1371/journal.pone.0256442, PubMed 34449791 -
Can the ampoules of covid-19 vaccine be used better?
Tidsskr. Nor. Laegeforen., 141 (2), 110 -
Humoral and cellular immune responses to two and three doses of SARS-CoV-2 vaccines in rituximab-treated patients with rheumatoid arthritis: a prospective, cohort study
Lancet Rheumatol, 4 (3), e177-e187
DOI 10.1016/S2665-9913(21)00394-5, PubMed 34977602 -
Inflammasomes and SARS-CoV-2 Infection
Viruses, 13 (12)
DOI 10.3390/v13122513, PubMed 34960782 -
Humoral immunity to SARS-CoV-2 mRNA vaccination in multiple sclerosis: the relevance of time since last rituximab infusion and first experience from sporadic revaccinations
J Neurol Neurosurg Psychiatry, 94 (1), 19-22
DOI 10.1136/jnnp-2021-327612, PubMed 34670844 -
The inflammatory response is related to circulatory failure after out-of-hospital cardiac arrest: A prospective cohort study
Resuscitation, 170, 115-125
DOI 10.1016/j.resuscitation.2021.11.026, PubMed 34838662 -
Correction: Lack of a site-specific phosphorylation of Presenilin 1 disrupts microglial gene networks and progenitors during development
PLoS One, 16 (2), e0247680
DOI 10.1371/journal.pone.0247680, PubMed 33606833 -
Development of a 1,2,4-Triazole-Based Lead Tankyrase Inhibitor: Part II
J Med Chem, 64 (24), 17936-17949
DOI 10.1021/acs.jmedchem.1c01264, PubMed 34878777 -
Persistent pulmonary pathology after COVID-19 is associated with high viral load, weak antibody response, and high levels of matrix metalloproteinase-9
Sci Rep, 11 (1), 23205
DOI 10.1038/s41598-021-02547-x, PubMed 34853380 -
Human KIR + CD8 + T cells target pathogenic T cells in Celiac disease and are active in autoimmune diseases and COVID-19
bioRxiv
DOI 10.1101/2021.12.23.473930, PubMed 34981055 -
OBITUARY Erik Thorsby (1938-2021)
HLA, 98 (1), 3-4
DOI 10.1111/tan.14290 -
Single-cell approaches to dissect adaptive immune responses involved in autoimmunity: the case of celiac disease
Mucosal Immunol, 15 (1), 51-63
DOI 10.1038/s41385-021-00452-0, PubMed 34531547 -
Longevity, clonal relationship, and transcriptional program of celiac disease-specific plasma cells
J Exp Med, 218 (2)
DOI 10.1084/jem.20200852, PubMed 33095260 -
TG2-gluten complexes as antigens for gluten-specific and transglutaminase-2 specific B cells in celiac disease
PLoS One, 16 (11), e0259082
DOI 10.1371/journal.pone.0259082, PubMed 34731200 -
TAD cliques predict key features of chromatin organization
BMC Genomics, 22 (1), 499
DOI 10.1186/s12864-021-07815-8, PubMed 34217222 -
Fusion of engineered albumin with factor IX Padua extends half-life and improves coagulant activity
Br J Haematol, 194 (2), 453-462
DOI 10.1111/bjh.17559, PubMed 34109608 -
Towards reproducibility in large-scale analysis of protein-protein interactions
Nat Methods, 18 (7), 720-721
DOI 10.1038/s41592-021-01202-7, PubMed 34211189 -
Intranasal delivery of a cDC1 targeted influenza vaccine with poly(I:C) enhances T cell responses and protects against influenza infection
Scand J Immunol, 95 (3), e13128
DOI 10.1111/sji.13128, PubMed 34923667 -
The allosteric modulation of complement C5 by knob domain peptides
Elife, 10
DOI 10.7554/eLife.63586, PubMed 33570492 -
Programmable half-life and anti-tumour effects of bispecific T-cell engager-albumin fusions with tuned FcRn affinity
Commun Biol, 4 (1), 310
DOI 10.1038/s42003-021-01790-2, PubMed 33686177 -
Spatial-proteomics reveals phospho-signaling dynamics at subcellular resolution
Nat Commun, 12 (1), 7113
DOI 10.1038/s41467-021-27398-y, PubMed 34876567 -
Half-life extension of efficiently produced DARPin serum albumin fusions as a function of FcRn affinity and recycling
Eur J Pharm Biopharm, 167, 104-113
DOI 10.1016/j.ejpb.2021.07.011, PubMed 34303832 -
Extended plasma half-life of albumin-binding domain fused human IgA upon pH-dependent albumin engagement of human FcRn in vitro and in vivo
MAbs, 13 (1), 1893888
DOI 10.1080/19420862.2021.1893888, PubMed 33691596 -
Immunoglobulin germline gene variation and its impact on human disease
Genes Immun, 22 (4), 205-217
DOI 10.1038/s41435-021-00145-5, PubMed 34175903 -
Germline polymorphisms and alternative splicing of human immunoglobulin light chain genes
iScience, 24 (10), 103192
DOI 10.1016/j.isci.2021.103192, PubMed 34693229 -
HLA class I depletion by citric acid, and irradiation of apheresis platelets for transfusion of refractory patients
Transfusion, 61 (4), 1222-1234
DOI 10.1111/trf.16282, PubMed 33580979 -
Proteomic study of apheresis platelets made HLA class I deficient for transfusion of refractory patients
Proteomics Clin Appl, 15 (6), e2100022
DOI 10.1002/prca.202100022, PubMed 34510746 -
Distinct Mitochondrial Remodeling During Mesoderm Differentiation in a Human-Based Stem Cell Model
Front Cell Dev Biol, 9, 744777
DOI 10.3389/fcell.2021.744777, PubMed 34722525 -
Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines
iScience, 24 (7), 102807
DOI 10.1016/j.isci.2021.102807, PubMed 34337362 -
Three waves of COVID-19 in a Norwegian local hospital
Tidsskr Nor Laegeforen, 141 (2)
DOI 10.4045/tidsskr.21.0750, PubMed 35107949 -
Sperm chromatin integrity and DNA methylation in Norwegian Red bulls of contrasting fertility
Mol Reprod Dev, 88 (3), 187-200
DOI 10.1002/mrd.23461, PubMed 33634579 -
SARS-CoV-2 neutralising antibody testing in Europe: towards harmonisation of neutralising antibody titres for better use of convalescent plasma and comparability of trial data
Euro Surveill, 26 (27)
DOI 10.2807/1560-7917.ES.2021.26.27.2100568, PubMed 34240697 -
A Conformational Change of Complement C5 Is Required for Thrombin-Mediated Cleavage, Revealed by a Novel Ex Vivo Human Whole Blood Model Preserving Full Thrombin Activity
J Immunol, 207 (6), 1641-1651
DOI 10.4049/jimmunol.2001471, PubMed 34380648 -
Quantification of Porcine Complement Activation Fragment C3a by a Neoepitope-Based Enzyme-Linked Immunosorbent Assay
Methods Mol Biol, 2227, 51-59
DOI 10.1007/978-1-0716-1016-9_5, PubMed 33847930 -
The story of an extraordinary year: Challenges and opportunities in responding to Covid-19
Transfus Apher Sci, 60 (2), 103092
DOI 10.1016/j.transci.2021.103092, PubMed 33612447 -
Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation
Sci Immunol, 6 (66), eabf2489
DOI 10.1126/sciimmunol.abf2489, PubMed 34932384 -
The Adenoviral E1B-55k Protein Present in HEK293 Cells Mediates Abnormal Accumulation of Key WNT Signaling Proteins in Large Cytoplasmic Aggregates
Genes (Basel), 12 (12)
DOI 10.3390/genes12121920, PubMed 34946869 -
Therapy-induced Deletion in 11q23 Leading to Fusion of KMT2A With ARHGEF12 and Development of B Lineage Acute Lymphoplastic Leukemia in a Child Treated for Acute Myeloid Leukemia Caused by t(9;11)(p21;q23)/KMT2A-MLLT3
Cancer Genomics Proteomics, 18 (1), 67-81
DOI 10.21873/cgp.20242, PubMed 33419897 -
International Forum on Gender Identification and Blood Collection: Summary
Vox Sang, 117 (3), 447-456
DOI 10.1111/vox.13192, PubMed 34545579 -
International Forum on Gender Identification and Blood Collection: Responses
Vox Sang, 117 (3), E21-E43
DOI 10.1111/vox.13193, PubMed 34545590 -
Regular Exercise May Restore Certain Age-Related Alterations of Adaptive Immunity and Rebalance Immune Regulation
Front Immunol, 12, 639308
DOI 10.3389/fimmu.2021.639308, PubMed 33936054 -
A porcine model of hemodialyzer reactions: roles of complement activation and rinsing back of extracorporeal blood
Ren Fail, 43 (1), 1609-1620
DOI 10.1080/0886022X.2021.2007127, PubMed 34882053 -
Frequency of Gluten-Reactive T Cells in Active Celiac Lesions Estimated by Direct Cell Cloning
Front Immunol, 12, 646163
DOI 10.3389/fimmu.2021.646163, PubMed 33796112 -
DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development
Atherosclerosis, 324, 123-132
DOI 10.1016/j.atherosclerosis.2021.02.023, PubMed 33714552 -
Proteomic analyses identify major vault protein as a prognostic biomarker for fatal prostate cancer
Carcinogenesis, 42 (5), 685-693
DOI 10.1093/carcin/bgab015, PubMed 33609362 -
Surfaceome and Exoproteome Dynamics in Dual-Species Pseudomonas aeruginosa and Staphylococcus aureus Biofilms
Front Microbiol, 12, 672975
DOI 10.3389/fmicb.2021.672975, PubMed 34248881 -
Response to: "Some considerations about γδ and CD8+ T-cell responses in blood after gluten challenge in treated celiac disease"
Mucosal Immunol, 14 (5), 1216-1217
DOI 10.1038/s41385-021-00422-6, PubMed 34108593 -
Circulating CD103+ γδ and CD8+ T cells are clonally shared with tissue-resident intraepithelial lymphocytes in celiac disease
Mucosal Immunol, 14 (4), 842-851
DOI 10.1038/s41385-021-00385-8, PubMed 33654213 -
Increased complement activation 3 to 6 h after trauma is a predictor of prolonged mechanical ventilation and multiple organ dysfunction syndrome: a prospective observational study
Mol Med, 27 (1), 35
DOI 10.1186/s10020-021-00286-3, PubMed 33832430 -
Liquid chromatography, a key tool for the advancement of single-cell omics analysis
Anal Chim Acta, 1178, 338551
DOI 10.1016/j.aca.2021.338551, PubMed 34482862 -
Modulation of virulence factors of Staphylococcus aureus by nanostructured surfaces
Mater. Des., 208, 109879
DOI 10.1016/j.matdes.2021.109879 -
Surface-Shaving Proteomics of Mycobacterium marinum Identifies Biofilm Subtype-Specific Changes Affecting Virulence, Tolerance, and Persistence
mSystems, 6 (3), e0050021
DOI 10.1128/mSystems.00500-21, PubMed 34156290 -
Thrombosis and Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination
N Engl J Med, 384 (22), 2124-2130
DOI 10.1056/NEJMoa2104882, PubMed 33835768 -
Electron Beam Sterilization of Poly(Methyl Methacrylate)-Physicochemical and Biological Aspects
Macromol Biosci, 21 (4), e2000379
DOI 10.1002/mabi.202000379, PubMed 33624923 -
Tuning gelatin-based hydrogel towards bioadhesive ocular tissue engineering applications
Bioact Mater, 6 (11), 3947-3961
DOI 10.1016/j.bioactmat.2021.03.042, PubMed 33937594 -
Autophagy modulates cell fate decisions during lineage commitment
Autophagy, 18 (8), 1915-1931
DOI 10.1080/15548627.2021.2008691, PubMed 34923909 -
Machine Learning Analysis of Naïve B-Cell Receptor Repertoires Stratifies Celiac Disease Patients and Controls
Front Immunol, 12, 627813
DOI 10.3389/fimmu.2021.627813, PubMed 33790900 -
Lung CD4+ T-cells in patients with lung fibrosis produce pro-fibrotic interleukin-13 together with interferon-γ
Eur Respir J, 57 (3)
DOI 10.1183/13993003.00983-2020, PubMed 33154027 -
Cluster of symptomatic silicone oil droplets following intravitreal injections: a 1-year observational study
BMJ Open Ophthalmol, 6 (1), e000764
DOI 10.1136/bmjophth-2021-000764, PubMed 34485702 -
Chronic treatment with terbutaline increases glucose and oleic acid oxidation and protein synthesis in cultured human myotubes
Curr Res Pharmacol Drug Discov, 2, 100039
DOI 10.1016/j.crphar.2021.100039, PubMed 34909668 -
Elevated plasma concentration of complement factor C5 is associated with risk of future venous thromboembolism
Blood, 138 (21), 2129-2137
DOI 10.1182/blood.2021010822, PubMed 34339498 -
Electromembrane Extraction and Mass Spectrometry for Liver Organoid Drug Metabolism Studies
Anal Chem, 93 (7), 3576-3585
DOI 10.1021/acs.analchem.0c05082, PubMed 33534551 -
Patient Derived Colonoids as Drug Testing Platforms-Critical Importance of Oxygen Concentration
Front Pharmacol, 12, 679741
DOI 10.3389/fphar.2021.679741, PubMed 34054553 -
Individualized VDJ recombination predisposes the available Ig sequence space
Genome Res, 31 (12), 2209-2224
DOI 10.1101/gr.275373.121, PubMed 34815307 -
Progress and challenges in mass spectrometry-based analysis of antibody repertoires
Trends Biotechnol, 40 (4), 463-481
DOI 10.1016/j.tibtech.2021.08.006, PubMed 34535228 -
Gut tissue-resident memory T cells in coeliac disease
Scand J Immunol, 95 (1), e13120
DOI 10.1111/sji.13120, PubMed 34796982 -
Erik Thorsby (1938-2021)
Immunogenetics, 73 (3), 203-205
DOI 10.1007/s00251-021-01218-5, PubMed 33956175 -
In memoriam: Erik Thorsby (1938-2021)
Scand. J. Immunol., 94 (1), e13055
DOI 10.1111/sji.13055 -
In Well-Treated Celiac Patients Low-Level Mucosal Inflammation Predicts Response to 14-day Gluten Challenge
Adv Sci (Weinh), 8 (4), 2003526
DOI 10.1002/advs.202003526, PubMed 33643806 -
Air Bubbles Activate Complement and Trigger Hemostasis and C3-Dependent Cytokine Release Ex Vivo in Human Whole Blood
J Immunol, 207 (11), 2828-2840
DOI 10.4049/jimmunol.2100308, PubMed 34732467 -
Open chest and pericardium facilitate transpulmonary passage of venous air emboli
Acta Anaesthesiol Scand, 65 (5), 648-655
DOI 10.1111/aas.13796, PubMed 33595102 -
When the restrictions are worse than the pandemic
Tidsskr Nor Laegeforen, 141 (3)
DOI 10.4045/tidsskr.21.0055, PubMed 33624978 -
Rapid systemic surge of IL-33 after severe human trauma: a prospective observational study
Mol Med, 27 (1), 29
DOI 10.1186/s10020-021-00288-1, PubMed 33771098 -
[An immunosuppressed woman in her seventies with night sweats and weight loss]
Tidsskr Nor Laegeforen, 141 (17)
DOI 10.4045/tidsskr.21.0332, PubMed 34813226 -
A human iPSC-astroglia neurodevelopmental model reveals divergent transcriptomic patterns in schizophrenia
Transl Psychiatry, 11 (1), 554
DOI 10.1038/s41398-021-01681-4, PubMed 34716291 -
The Imbalance of Circulating Follicular T Helper Cell Subsets in Primary Sjögren's Syndrome Associates With Serological Alterations and Abnormal B-Cell Distribution
Front Immunol, 12, 639975
DOI 10.3389/fimmu.2021.639975, PubMed 33815392 -
Integration of T helper and BCR signals governs enhanced plasma cell differentiation of memory B cells by regulation of CD45 phosphatase activity
Cell Rep, 36 (6), 109525
DOI 10.1016/j.celrep.2021.109525, PubMed 34380042 -
The Norwegian experience with nationwide implementation of fetal RHD genotyping and targeted routine antenatal anti-D prophylaxis
Transfus Med, 31 (5), 314-321
DOI 10.1111/tme.12772, PubMed 33821537 -
Complement ratios C3bc/C3 and sC5b-9/C5 do not increase the sensitivity of detecting acute complement activation systemically
Mol Immunol, 141, 273-279
DOI 10.1016/j.molimm.2021.11.016, PubMed 34906905 -
The Expression of NTAL and Its Protein Interactors Is Associated With Clinical Outcomes in Acute Myeloid Leukemia
Mol Cell Proteomics, 20, 100091
DOI 10.1016/j.mcpro.2021.100091, PubMed 33971369 -
Increased Local Inflammatory Response to MOC31PE Immunotoxin After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
Ann Surg Oncol, 28 (9), 5252-5262
DOI 10.1245/s10434-021-10022-0, PubMed 34019185 -
ASO Author Reflections: The Peritoneum is an Active Immunological Compartment
Ann Surg Oncol, 28 (9), 5263-5264
DOI 10.1245/s10434-021-10036-8, PubMed 33939046 -
Trends in seroprevalence of SARS-CoV-2 and infection fatality rate in the Norwegian population through the first year of the COVID-19 pandemic
Influenza Other Respir Viruses, 16 (2), 204-212
DOI 10.1111/irv.12932, PubMed 34751488 -
Mutations inhibiting KDM4B drive ALT activation in ATRX-mutated glioblastomas
Nat Commun, 12 (1), 2584
DOI 10.1038/s41467-021-22543-z, PubMed 33972520 -
[How effective is the COVID-19 vaccine for older persons?]
Tidsskr Nor Laegeforen, 141 (18)
DOI 10.4045/tidsskr.21.0748, PubMed 34911279 -
Plasma extracellular vesicles in people living with HIV and type 2 diabetes are related to microbial translocation and cardiovascular risk
Sci Rep, 11 (1), 21936
DOI 10.1038/s41598-021-01334-y, PubMed 34754007 -
HLA-B*27 typing using a triplex real time PCR in routine laboratory
HLA, 98 (4), 366-369
DOI 10.1111/tan.14386, PubMed 34342381 -
Narcolepsy type 1 patients have lower levels of effector memory CD4+ T cells compared to their siblings when controlling for H1N1-(Pandemrix™)-vaccination and HLA DQB1∗06:02 status
Sleep Med, 85, 271-279
DOI 10.1016/j.sleep.2021.07.024, PubMed 34388506 -
High nocturnal sleep fragmentation is associated with low T lymphocyte P2Y11 protein levels in narcolepsy type 1
Sleep, 44 (8)
DOI 10.1093/sleep/zsab062, PubMed 33710305 -
Low-Input RNA-Sequencing in Patients with Cartilage Lesions, Osteoarthritis, and Healthy Cartilage
Cartilage, 13 (1_suppl), 550S-562S
DOI 10.1177/19476035211057245, PubMed 34775802 -
Design of a Proteolytically Stable Sodium-Calcium Exchanger 1 Activator Peptide for In Vivo Studies
Front Pharmacol, 12, 638646
DOI 10.3389/fphar.2021.638646, PubMed 34163352 -
Morten Harboe (1929-2021), one of the founders of Scandinavian Journal of Immunology OBITUARY
Scand. J. Immunol., 94 (1), e13054
DOI 10.1111/sji.13054 -
Elevated Terminal C5b-9 Complement Complex 10 Weeks Post Kidney Transplantation Was Associated With Reduced Long-Term Patient and Kidney Graft Survival
Front Immunol, 12, 738927
DOI 10.3389/fimmu.2021.738927, PubMed 34759922 -
Immunobiology and conflicting roles of the human CD161 receptor in T cells
Scand J Immunol, 94 (3), e13090
DOI 10.1111/sji.13090, PubMed 35611672 -
C-type lectin-like CD161 is not a co-signalling receptor in gluten-reactive CD4 + T cells
Scand J Immunol, 93 (6), e13016
DOI 10.1111/sji.13016, PubMed 33368526 -
Fine mapping of the HLA locus in Parkinson's disease in Europeans
NPJ Parkinsons Dis, 7 (1), 84
DOI 10.1038/s41531-021-00231-5, PubMed 34548497 -
Matrix M Adjuvanted H5N1 Vaccine Elicits Broadly Neutralizing Antibodies and Neuraminidase Inhibiting Antibodies in Humans That Correlate With In Vivo Protection
Front Immunol, 12, 747774
DOI 10.3389/fimmu.2021.747774, PubMed 34887855 -
Innate Immune Invisible Ultrasmall Gold Nanoparticles-Framework for Synthesis and Evaluation
ACS Appl Mater Interfaces, 13 (20), 23410-23422
DOI 10.1021/acsami.1c02834, PubMed 33978409 -
Prevention of Bone Destruction by Mechanical Loading Is Not Enhanced by the Bruton's Tyrosine Kinase Inhibitor CC-292 in Myeloma Bone Disease
Int J Mol Sci, 22 (8)
DOI 10.3390/ijms22083840, PubMed 33917250 -
The neonatal Fc receptor in mucosal immune regulation
Scand J Immunol, 93 (2), e13017
DOI 10.1111/sji.13017, PubMed 33351196 -
Blood neurofilament light concentration at admittance: a potential prognostic marker in COVID-19
J Neurol, 268 (10), 3574-3583
DOI 10.1007/s00415-021-10517-6, PubMed 33743046
Publications 2020
-
Pancreas-on-a-Chip Technology for Transplantation Applications
Curr Diab Rep, 20 (12), 72
DOI 10.1007/s11892-020-01357-1, PubMed 33206261 -
Engineered albumin-functionalized nanoparticles for improved FcRn binding enhance oral delivery of insulin
J Control Release, 327, 161-173
DOI 10.1016/j.jconrel.2020.08.005, PubMed 32771477 -
A method for differentiating human induced pluripotent stem cells toward functional cardiomyocytes in 96-well microplates
Sci Rep, 10 (1), 18498
DOI 10.1038/s41598-020-73656-2, PubMed 33116175 -
Intestinal inflammatory profile shows increase in a diversity of biomarkers in irritable bowel syndrome
Scand J Gastroenterol, 55 (5), 537-542
DOI 10.1080/00365521.2020.1754455, PubMed 32329383 -
An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics
Sci Transl Med, 12 (565)
DOI 10.1126/scitranslmed.abb0580, PubMed 33055243 -
Five decades with grandparent donors: The Norwegian strategy and experience
Pediatr Transplant, 24 (6), e13751
DOI 10.1111/petr.13751, PubMed 32485019 -
Lamina-associated domains: peripheral matters and internal affairs
Genome Biol, 21 (1), 85
DOI 10.1186/s13059-020-02003-5, PubMed 32241294 -
Extensive Changes in Transcriptomic "Fingerprints" and Immunological Cells in the Large Organs of Patients Dying of Acute Septic Shock and Multiple Organ Failure Caused by Neisseria meningitidis
Front Cell Infect Microbiol, 10, 42
DOI 10.3389/fcimb.2020.00042, PubMed 32154187 -
A DNA Vaccine That Encodes an Antigen-Presenting Cell-Specific Heterodimeric Protein Protects against Cancer and Influenza
Mol Ther Methods Clin Dev, 17, 378-392
DOI 10.1016/j.omtm.2020.01.007, PubMed 32128342 -
Viral nucleoprotein antibodies activate TRIM21 and induce T cell immunity
EMBO J, 40 (5), e106228
DOI 10.15252/embj.2020106228, PubMed 33258165 -
Intracellular neutralisation of rotavirus by VP6-specific IgG
PLoS Pathog, 16 (8), e1008732
DOI 10.1371/journal.ppat.1008732, PubMed 32750093 -
Systemic Inflammation Persists the First Year after Mild Traumatic Brain Injury: Results from the Prospective Trondheim Mild Traumatic Brain Injury Study
J Neurotrauma, 37 (19), 2120-2130
DOI 10.1089/neu.2019.6963, PubMed 32326805 -
Methionine- and Choline-Deficient Diet Enhances Adipose Lipolysis and Leptin Release in aP2-Cre Fatp4-Knockout Mice
Mol Nutr Food Res, 64 (22), e2000361
DOI 10.1002/mnfr.202000361, PubMed 32991778 -
B cell tolerance and antibody production to the celiac disease autoantigen transglutaminase 2
J Exp Med, 217 (2)
DOI 10.1084/jem.20190860, PubMed 31727780 -
TLR8 and complement C5 induce cytokine release and thrombin activation in human whole blood challenged with Gram-positive bacteria
J Leukoc Biol, 107 (4), 673-683
DOI 10.1002/JLB.3A0120-114R, PubMed 32083344 -
Distinct Pattern of Endoplasmic Reticulum Protein Processing and Extracellular Matrix Proteins in Functioning and Silent Corticotroph Pituitary Adenomas
Cancers (Basel), 12 (10)
DOI 10.3390/cancers12102980, PubMed 33066652 -
NETs analysed by novel calprotectin-based assays in blood donors and patients with multiple myeloma or rheumatoid arthritis: A pilot study
Scand J Immunol, 91 (5), e12870
DOI 10.1111/sji.12870, PubMed 32034957 -
Targeting Antigens to Different Receptors on Conventional Type 1 Dendritic Cells Impacts the Immune Response
J Immunol, 205 (3), 661-673
DOI 10.4049/jimmunol.1901119, PubMed 32591401 -
Fecal microbiota transplantation in systemic sclerosis: A double-blind, placebo-controlled randomized pilot trial
PLoS One, 15 (5), e0232739
DOI 10.1371/journal.pone.0232739, PubMed 32437393 -
Identification of Antiestrogen-Bound Estrogen Receptor α Interactomes in Hormone-Responsive Human Breast Cancer Cell Nuclei
Proteomics, 20 (19-20), e2000135
DOI 10.1002/pmic.202000135, PubMed 32865868 -
In vivo Cell Tracking Using Non-invasive Imaging of Iron Oxide-Based Particles with Particular Relevance for Stem Cell-Based Treatments of Neurological and Cardiac Disease
Mol Imaging Biol, 22 (6), 1469-1488
DOI 10.1007/s11307-019-01440-4, PubMed 31802361 -
Quantitative Changes in the Mitochondrial Proteome of Cerebellar Synaptosomes From Preclinical Cystatin B-Deficient Mice
Front Mol Neurosci, 13, 570640
DOI 10.3389/fnmol.2020.570640, PubMed 33281550 -
Anterior segment parameters associated with extramuscular manifestations in polymyositis and dermatomyositis
Int J Ophthalmol, 13 (9), 1443-1450
DOI 10.18240/ijo.2020.09.17, PubMed 32953585 -
Complement Activation in 22q11.2 Deletion Syndrome
J Clin Immunol, 40 (3), 515-523
DOI 10.1007/s10875-020-00766-x, PubMed 32152940 -
Induction of Cross-Reactive and Protective Antibody Responses After DNA Vaccination With MHCII-Targeted Stem Domain From Influenza Hemagglutinin
Front Immunol, 11, 431
DOI 10.3389/fimmu.2020.00431, PubMed 32269566 -
HLA-DPB1 mismatch reduce relapse and improve survival in T-cell replete unrelated donor allogeneic stem cell transplantation
Bone Marrow Transplant, 55 (8), 1658-1661
DOI 10.1038/s41409-020-0827-3, PubMed 32054997 -
Can medicinal mushrooms have prophylactic or therapeutic effect against COVID-19 and its pneumonic superinfection and complicating inflammation?
Scand J Immunol, 93 (1), e12937
DOI 10.1111/sji.12937, PubMed 32657436 -
Antitumor, Anti-Inflammatory and Antiallergic Effects of Agaricus blazei Mushroom Extract and the Related Medicinal Basidiomycetes Mushrooms, Hericium erinaceus and Grifola frondosa: A Review of Preclinical and Clinical Studies
Nutrients, 12 (5)
DOI 10.3390/nu12051339, PubMed 32397163 -
Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients
Proc Natl Acad Sci U S A, 117 (40), 25018-25025
DOI 10.1073/pnas.2010540117, PubMed 32943538 -
Anti-inflammatory effects of non-statin low-density lipoprotein cholesterol-lowering drugs: an unused potential?
Scand Cardiovasc J, 54 (5), 274-279
DOI 10.1080/14017431.2020.1775878, PubMed 32500743 -
FcRn is a CD32a coreceptor that determines susceptibility to IgG immune complex-driven autoimmunity
J Exp Med, 217 (10)
DOI 10.1084/jem.20200359, PubMed 32658257 -
CD4+ T-cell killing of multiple myeloma cells is mediated by resident bone marrow macrophages
Blood Adv, 4 (12), 2595-2605
DOI 10.1182/bloodadvances.2020001434, PubMed 32544236 -
COVID-19: Symptoms, course of illness and use of clinical scoring systems for the first 42 patients admitted to a Norwegian local hospital
Tidsskr Nor Laegeforen, 140 (7)
DOI 10.4045/tidsskr.20.0301, PubMed 32378844 -
Evidence That Pathogenic Transglutaminase 2 in Celiac Disease Derives From Enterocytes
Gastroenterology, 159 (2), 788-790
DOI 10.1053/j.gastro.2020.04.018, PubMed 32302613 -
Autoimmunity provoked by foreign antigens
Science, 368 (6487), 132-133
DOI 10.1126/science.aay3037, PubMed 32273455 -
HLA and sleep parameter associations in post-H1N1 narcolepsy type 1 patients and first-degree relatives
Sleep, 43 (3)
DOI 10.1093/sleep/zsz239, PubMed 31606740 -
Preparedness and hospital building: what should we learn from COVID-19?
Tidsskr. Nor. Laegeforen., 140 (10), 982-984 -
The government's "corona commission" is not very representative and has an incompetent leader
Tidsskr. Nor. Laegeforen., 140 (10), 974 -
CD14 inhibition improves survival and attenuates thrombo-inflammation and cardiopulmonary dysfunction in a baboon model of Escherichia coli sepsis
J Thromb Haemost, 19 (2), 429-443
DOI 10.1111/jth.15162, PubMed 33174372 -
A Small-Molecule Tankyrase Inhibitor Reduces Glioma Stem Cell Proliferation and Sphere Formation
Cancers (Basel), 12 (6)
DOI 10.3390/cancers12061630, PubMed 32575464 -
Pancreatic cancer cells show lower oleic acid oxidation and their conditioned medium inhibits oleic acid oxidation in human myotubes
Pancreatology, 20 (4), 676-682
DOI 10.1016/j.pan.2020.04.014, PubMed 32360002 -
PD-1 Blockade Reinvigorates Bone Marrow CD8+ T Cells from Patients with Multiple Myeloma in the Presence of TGFβ Inhibitors
Clin Cancer Res, 26 (7), 1644-1655
DOI 10.1158/1078-0432.CCR-19-0267, PubMed 31941832 -
Human Leukocyte Antigen alleles associated with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Sci Rep, 10 (1), 5267
DOI 10.1038/s41598-020-62157-x, PubMed 32210306 -
NHDL, a recombinant VL/VH hybrid antibody control for IgG2/4 antibodies
MAbs, 12 (1), 1686319
DOI 10.1080/19420862.2019.1686319, PubMed 31671278 -
Disease-specific phenotypes in iPSC-derived neural stem cells with POLG mutations
EMBO Mol Med, 12 (10), e12146
DOI 10.15252/emmm.202012146, PubMed 32840960 -
N-acetylcysteine amide ameliorates mitochondrial dysfunction and reduces oxidative stress in hiPSC-derived dopaminergic neurons with POLG mutation
Exp Neurol, 337, 113536
DOI 10.1016/j.expneurol.2020.113536, PubMed 33264635 -
Correction: Towards dual inhibitors of the MET kinase and WNT signaling pathway; design, synthesis and biological evaluation
RSC Adv, 10 (9), 4927
DOI 10.1039/d0ra90007a, PubMed 35503286 -
Characterization of T-cell receptor transgenic mice recognizing immunodominant HLA-DQ2.5-restricted gluten epitopes
Eur J Immunol, 51 (4), 1002-1005
DOI 10.1002/eji.202048859, PubMed 33368209 -
Absence of NLRP3 Inflammasome in Hematopoietic Cells Reduces Adverse Remodeling After Experimental Myocardial Infarction
JACC Basic Transl Sci, 5 (12), 1210-1224
DOI 10.1016/j.jacbts.2020.09.013, PubMed 33426377 -
Author Correction: Dendritic cell targeted Ccl3- and Xcl1-fusion DNA vaccines differ in induced immune responses and optimal delivery site
Sci Rep, 10 (1), 5944
DOI 10.1038/s41598-020-62688-3, PubMed 32231213 -
[COVID-19: evidence, eminence, or experience- based treatment?]
Tidsskr Nor Laegeforen, 140 (12)
DOI 10.4045/tidsskr.20.0649, PubMed 32900165 -
Gut Microbiota-Dependent Trimethylamine N-Oxide Associates With Inflammation in Common Variable Immunodeficiency
Front Immunol, 11, 574500
DOI 10.3389/fimmu.2020.574500, PubMed 33042155 -
Function and Regulation of Noncanonical Caspase-4/5/11 Inflammasome
J Immunol, 204 (12), 3063-3069
DOI 10.4049/jimmunol.2000373, PubMed 32513874 -
Inflammasomes: Exosomal miRNAs loaded for action
J Cell Biol, 219 (10)
DOI 10.1083/jcb.202008130, PubMed 32970793 -
Polymorphisms in human immunoglobulin heavy chain variable genes and their upstream regions
Nucleic Acids Res, 48 (10), 5499-5510
DOI 10.1093/nar/gkaa310, PubMed 32365177 -
Correction: Minimal residual disease quantification by flow cytometry provides reliable risk stratification in T-cell acute lymphoblastic leukemia
Leukemia, 34 (6), 1719-1720
DOI 10.1038/s41375-019-0672-9, PubMed 31822778 -
Complement in sepsis-when science meets clinics
FEBS Lett, 594 (16), 2621-2632
DOI 10.1002/1873-3468.13881, PubMed 32621378 -
National Early Warning Score 2 (NEWS2) on admission predicts severe disease and in-hospital mortality from Covid-19 - a prospective cohort study
Scand J Trauma Resusc Emerg Med, 28 (1), 66
DOI 10.1186/s13049-020-00764-3, PubMed 32660623 -
An intact C-terminal end of albumin is required for its long half-life in humans
Commun Biol, 3 (1), 181
DOI 10.1038/s42003-020-0903-7, PubMed 32313072 -
Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis
EBioMedicine, 60, 102985
DOI 10.1016/j.ebiom.2020.102985, PubMed 32927275 -
A Complement C3-Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity
J Immunol, 205 (8), 2287-2300
DOI 10.4049/jimmunol.2000752, PubMed 32938727 -
Sjögren syndrome/scleroderma autoantigen 1 is a direct Tankyrase binding partner in cancer cells
Commun Biol, 3 (1), 123
DOI 10.1038/s42003-020-0851-2, PubMed 32170109 -
Intravenous Cyclophosphamide in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. An Open-Label Phase II Study
Front Med (Lausanne), 7, 162
DOI 10.3389/fmed.2020.00162, PubMed 32411717 -
Mechanical loading prevents bone destruction and exerts anti-tumor effects in the MOPC315.BM.Luc model of myeloma bone disease
Acta Biomater, 119, 247-258
DOI 10.1016/j.actbio.2020.10.041, PubMed 33130307 -
Growth Mode and Physiological State of Cells Prior to Biofilm Formation Affect Immune Evasion and Persistence of Staphylococcus aureus
Microorganisms, 8 (1)
DOI 10.3390/microorganisms8010106, PubMed 31940921 -
Platelets mediate serological memory to neutralize viruses in vitro and in vivo
Blood Adv, 4 (16), 3971-3976
DOI 10.1182/bloodadvances.2020001786, PubMed 32841338 -
Complement component C3 and the TLR co-receptor CD14 are not involved in angiotensin II induced cardiac remodelling
Biochem Biophys Res Commun, 523 (4), 867-873
DOI 10.1016/j.bbrc.2020.01.018, PubMed 31955888 -
Sputter Deposition of Titanium on Poly(Methyl Methacrylate) Enhances Corneal Biocompatibility
Transl Vis Sci Technol, 9 (13), 41
DOI 10.1167/tvst.9.13.41, PubMed 33442495 -
Avoiding ambient air in test tubes during incubations of human whole-blood minimizes complement background activation
J Immunol Methods, 487, 112876
DOI 10.1016/j.jim.2020.112876, PubMed 33031792 -
Second-Tier Next Generation Sequencing Integrated in Nationwide Newborn Screening Provides Rapid Molecular Diagnostics of Severe Combined Immunodeficiency
Front Immunol, 11, 1417
DOI 10.3389/fimmu.2020.01417, PubMed 32754152 -
[Oncorheumatology: relationship between malignancies and musculoskeletal diseases]
Orv Hetil, 161 (28), 1151-1165
DOI 10.1556/650.2020.31800, PubMed 32609623 -
Eight pillars of oncorheumatology: Crossroads between malignancies and musculoskeletal diseases
Autoimmun Rev, 19 (11), 102658
DOI 10.1016/j.autrev.2020.102658, PubMed 32942035 -
Respiratory chain signalling is essential for adaptive remodelling following cardiac ischaemia
J Cell Mol Med, 24 (6), 3534-3548
DOI 10.1111/jcmm.15043, PubMed 32040259 -
Maternal Microchimerism in Cord Blood and Risk of Celiac Disease in Childhood
J Pediatr Gastroenterol Nutr, 71 (3), 321-327
DOI 10.1097/MPG.0000000000002811, PubMed 32833392 -
A molecular basis for the T cell response in HLA-DQ2.2 mediated celiac disease
Proc Natl Acad Sci U S A, 117 (6), 3063-3073
DOI 10.1073/pnas.1914308117, PubMed 31974305 -
Onecut-dependent Nkx6.2 transcription factor expression is required for proper formation and activity of spinal locomotor circuits
Sci Rep, 10 (1), 996
DOI 10.1038/s41598-020-57945-4, PubMed 31969659 -
Author Correction: Onecut-dependent Nkx6.2 transcription factor expression is required for proper formation and activity of spinal locomotor circuits
Sci Rep, 10 (1), 13531
DOI 10.1038/s41598-020-70339-w, PubMed 32764632 -
Cardiorespiratory fitness on a treadmill in an adult cystic fibrosis population
BMJ Open Sport Exerc Med, 6 (1), e000765
DOI 10.1136/bmjsem-2020-000765, PubMed 32843991 -
Choice of immunoassay to evaluate porcine cytokine levels
Vet Immunol Immunopathol, 230, 110129
DOI 10.1016/j.vetimm.2020.110129, PubMed 33059181 -
The complement component C5 is not responsible for the alternative pathway activity in rabbit erythrocyte hemolytic assays during eculizumab treatment
Cell Mol Immunol, 17 (6), 653-655
DOI 10.1038/s41423-020-0406-y, PubMed 32210393 -
Unrestrained ESCRT-III drives micronuclear catastrophe and chromosome fragmentation
Nat Cell Biol, 22 (7), 856-867
DOI 10.1038/s41556-020-0537-5, PubMed 32601372 -
Tankyrase inhibition ameliorates lipid disorder via suppression of PGC-1α PARylation in db/db mice
Int J Obes (Lond), 44 (8), 1691-1702
DOI 10.1038/s41366-020-0573-z, PubMed 32317752 -
Repurposed Antiviral Drugs for Covid-19 - Interim WHO Solidarity Trial Results
N Engl J Med, 384 (6), 497-511
DOI 10.1056/NEJMoa2023184, PubMed 33264556 -
Preclinical Lead Optimization of a 1,2,4-Triazole Based Tankyrase Inhibitor
J Med Chem, 63 (13), 6834-6846
DOI 10.1021/acs.jmedchem.0c00208, PubMed 32511917 -
Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models
Commun Biol, 3 (1), 196
DOI 10.1038/s42003-020-0916-2, PubMed 32332858 -
Soluble collectin-12 mediates C3-independent docking of properdin that activates the alternative pathway of complement
Elife, 9
DOI 10.7554/eLife.60908, PubMed 32909942 -
An Early Myeloma Bone Disease Model in Skeletally Mature Mice as a Platform for Biomaterial Characterization of the Extracellular Matrix
J Oncol, 2020, 3985315
DOI 10.1155/2020/3985315, PubMed 32684931 -
Intestinal Epithelial Cells Express Immunomodulatory ISG15 During Active Ulcerative Colitis and Crohn's Disease
J Crohns Colitis, 14 (7), 920-934
DOI 10.1093/ecco-jcc/jjaa022, PubMed 32020185 -
How does COVID-19 affect the brain?
Tidsskr Nor Laegeforen, 140 (10)
DOI 10.4045/tidsskr.20.0444, PubMed 32602331
Publications 2019
-
Multi-pathway Protective Effects of MicroRNAs on Human Chondrocytes in an In Vitro Model of Osteoarthritis
Mol Ther Nucleic Acids, 17, 776-790
DOI 10.1016/j.omtn.2019.07.011, PubMed 31446120 -
Interaction Proteomics Identifies ERbeta Association with Chromatin Repressive Complexes to Inhibit Cholesterol Biosynthesis and Exert An Oncosuppressive Role in Triple-negative Breast Cancer
Mol Cell Proteomics, 19 (2), 245-260
DOI 10.1074/mcp.RA119.001817, PubMed 31792072 -
Enhanced germinal center reaction by targeting vaccine antigen to major histocompatibility complex class II molecules
NPJ Vaccines, 4, 9
DOI 10.1038/s41541-019-0101-0, PubMed 30775000 -
Evaluation of Objective Signs and Subjective Symptoms of Dry Eye Disease in Patients with Inflammatory Bowel Disease
Biomed Res Int, 2019, 8310583
DOI 10.1155/2019/8310583, PubMed 30729131 -
Resident memory CD8 T cells persist for years in human small intestine
J Exp Med, 216 (10), 2412-2426
DOI 10.1084/jem.20190414, PubMed 31337737 -
Diagnosis and outcome of acute respiratory failure in immunocompromised patients after bronchoscopy
Eur Respir J, 54 (1)
DOI 10.1183/13993003.02442-2018, PubMed 31109985 -
Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex-mediated immune responses
Sci Adv, 5 (12), eaax9586
DOI 10.1126/sciadv.aax9586, PubMed 31897428 -
Interstitial cells in calcified aortic valves have reduced differentiation potential and stem cell-like properties
Sci Rep, 9 (1), 12934
DOI 10.1038/s41598-019-49016-0, PubMed 31506459 -
CD4+ T cells indirectly kill tumor cells via induction of cytotoxic macrophages in mouse models
Cancer Immunol Immunother, 68 (11), 1865-1873
DOI 10.1007/s00262-019-02374-0, PubMed 31448380 -
Complement C4 Prevents Viral Infection through Capsid Inactivation
Cell Host Microbe, 25 (4), 617-629.e7
DOI 10.1016/j.chom.2019.02.016, PubMed 30926239 -
Key role of the number of complement receptor 1 on erythrocytes for binding of Escherichia coli to erythrocytes and for leukocyte phagocytosis and oxidative burst in human whole blood
Mol Immunol, 114, 139-148
DOI 10.1016/j.molimm.2019.07.014, PubMed 31352230 -
EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology
SLAS Discov, 24 (3), 398-413
DOI 10.1177/2472555218816276, PubMed 30616481 -
Nuclear Lamin B1 Interactions With Chromatin During the Circadian Cycle Are Uncoupled From Periodic Gene Expression
Front Genet, 10, 917
DOI 10.3389/fgene.2019.00917, PubMed 31632442 -
[Premature infants should receive early vaccination against rotavirus]
Tidsskr Nor Laegeforen, 139 (10)
DOI 10.4045/tidsskr.19.0079, PubMed 31238656 -
Corrigendum to "Changes in cytokines during treatment of elderly, hospitalized psychiatric patients-A naturalistic study" [Psychoneuroendocrinology, 108C (2019), 135-139]
Psychoneuroendocrinology, 109, 104427
DOI 10.1016/j.psyneuen.2019.104427, PubMed 31537376 -
Changes in cytokines during treatment of elderly, hospitalized psychiatric patients - a naturalistic study
Psychoneuroendocrinology, 108, 135-139
DOI 10.1016/j.psyneuen.2019.06.014, PubMed 31276906 -
Deciphering myeloid-derived suppressor cells: isolation and markers in humans, mice and non-human primates
Cancer Immunol Immunother, 68 (4), 687-697
DOI 10.1007/s00262-019-02302-2, PubMed 30684003 -
Editorial: The Role of Complement in Health and Disease
Front Immunol, 10, 1869
DOI 10.3389/fimmu.2019.01869, PubMed 31440250 -
The PI3K p110δ Isoform Inhibitor Idelalisib Preferentially Inhibits Human Regulatory T Cell Function
J Immunol, 202 (5), 1397-1405
DOI 10.4049/jimmunol.1701703, PubMed 30692213 -
Distinct phenotype of CD4+ T cells driving celiac disease identified in multiple autoimmune conditions
Nat Med, 25 (5), 734-737
DOI 10.1038/s41591-019-0403-9, PubMed 30911136 -
Therapeutic and Diagnostic Implications of T Cell Scarring in Celiac Disease and Beyond
Trends Mol Med, 25 (10), 836-852
DOI 10.1016/j.molmed.2019.05.009, PubMed 31331739 -
Noninvasive fetal RHD genotyping to guide targeted anti-D prophylaxis-an external quality assessment workshop
Vox Sang, 114 (4), 386-393
DOI 10.1111/vox.12768, PubMed 30834546 -
Finding Friends in the Crowd: Three-Dimensional Cliques of Topological Genomic Domains
Front Genet, 10, 602
DOI 10.3389/fgene.2019.00602, PubMed 31275364 -
Corneal Manifestations of Inflammatory Bowel Disease
Semin Ophthalmol, 34 (7-8), 543-550
DOI 10.1080/08820538.2019.1684525, PubMed 31657260 -
On the immune response to barley in celiac disease: Biased and public T-cell receptor usage to a barley unique and immunodominant gluten epitope
Eur J Immunol, 50 (2), 256-269
DOI 10.1002/eji.201948253, PubMed 31628754 -
Elevated Complement C3 and C4 Levels are Associated with Postnatal Pregnancy-Related Venous Thrombosis
Thromb Haemost, 119 (9), 1481-1488
DOI 10.1055/s-0039-1692426, PubMed 31254974 -
Single-cell TCR sequencing of gut intraepithelial γδ T cells reveals a vast and diverse repertoire in celiac disease
Mucosal Immunol, 13 (2), 313-321
DOI 10.1038/s41385-019-0222-9, PubMed 31728027 -
Deep sequencing of a recurrent oligodendroglioma and the derived xenografts reveals new insights into the evolution of human oligodendroglioma and candidate driver genes
Oncotarget, 10 (38), 3641-3653
DOI 10.18632/oncotarget.26950, PubMed 31217899 -
Interplay of lamin A and lamin B LADs on the radial positioning of chromatin
Nucleus, 10 (1), 7-20
DOI 10.1080/19491034.2019.1570810, PubMed 30663495 -
TRIM21-From Intracellular Immunity to Therapy
Front Immunol, 10, 2049
DOI 10.3389/fimmu.2019.02049, PubMed 31555278 -
A TRAV26-1-encoded recognition motif focuses the biased T cell response in celiac disease
Eur J Immunol, 50 (1), 142-145
DOI 10.1002/eji.201948235, PubMed 31580480 -
Mosaic deletion patterns of the human antibody heavy chain gene locus shown by Bayesian haplotyping
Nat Commun, 10 (1), 628
DOI 10.1038/s41467-019-08489-3, PubMed 30733445 -
Cytokine release and gastrointestinal symptoms after gluten challenge in celiac disease
Sci Adv, 5 (8), eaaw7756
DOI 10.1126/sciadv.aaw7756, PubMed 31457091 -
[Biosimilar drugs – just as good, and much cheaper]
Tidsskr Nor Laegeforen, 139 (6)
DOI 10.4045/tidsskr.19.0051, PubMed 30917643 -
The synthetic antimicrobial peptide LTX21 induces inflammatory responses in a human whole blood model and a murine peritoneum model
APMIS, 127 (6), 475-483
DOI 10.1111/apm.12946, PubMed 30916807 -
Cholesterol Crystals Induce Coagulation Activation through Complement-Dependent Expression of Monocytic Tissue Factor
J Immunol, 203 (4), 853-863
DOI 10.4049/jimmunol.1900503, PubMed 31270150 -
Targeting of HA to chemokine receptors induces strong and cross-reactive T cell responses after DNA vaccination in pigs
Vaccine, 38 (6), 1280-1285
DOI 10.1016/j.vaccine.2019.11.084, PubMed 31836256 -
Endocytosis Deficient Murine Xcl1-Fusion Vaccine Enhances Protective Antibody Responses in Mice
Front Immunol, 10, 1086
DOI 10.3389/fimmu.2019.01086, PubMed 31156636 -
Perioperative Infusion of Glucagon-Like Peptide-1 Prevents Insulin Resistance After Surgical Trauma in Female Pigs
Endocrinology, 160 (12), 2892-2902
DOI 10.1210/en.2019-00374, PubMed 31589305 -
Comparison of cytokine changes in three different lipoprotein apheresis systems in an ex vivo whole blood model
J Clin Apher, 35 (2), 104-116
DOI 10.1002/jca.21765, PubMed 31782556 -
Congratulations as a complete doctor?
Tidsskr. Nor. Laegeforen., 139 (10), 966 -
[Congratulations on becoming a fully qualified doctor?]
Tidsskr Nor Laegeforen, 139 (10)
DOI 10.4045/tidsskr.19.0103, PubMed 31238666 -
Structural and Functional Dynamics of Staphylococcus aureus Biofilms and Biofilm Matrix Proteins on Different Clinical Materials
Microorganisms, 7 (12)
DOI 10.3390/microorganisms7120584, PubMed 31756969 -
Tumor necrosis factor inhibitors are associated with reduced complement activation in spondylarthropathies: An observational study
PLoS One, 14 (7), e0220079
DOI 10.1371/journal.pone.0220079, PubMed 31335881 -
Selective and marked decrease of complement receptor C5aR2 in human thoracic aortic aneurysms: a dysregulation with potential inflammatory effects
Open Heart, 6 (2), e001098
DOI 10.1136/openhrt-2019-001098, PubMed 31798913 -
The novel HLA-A*03 variant, HLA-A*03:08:01:02, detected by sequencing-based typing
HLA, 94 (1), 60-61
DOI 10.1111/tan.13549, PubMed 30977308 -
Epitope Selection for HLA-DQ2 Presentation: Implications for Celiac Disease and Viral Defense
J Immunol, 202 (9), 2558-2569
DOI 10.4049/jimmunol.1801454, PubMed 30926644 -
B cell receptor ligation induces display of V-region peptides on MHC class II molecules to T cells
Proc Natl Acad Sci U S A, 116 (51), 25850-25859
DOI 10.1073/pnas.1902836116, PubMed 31796587 -
The novel HLA-A*01 variant, HLA-A*01:308N, detected by sequencing-based typing
HLA, 94 (3), 312
DOI 10.1111/tan.13606, PubMed 31144452 -
Complement activation assessed by the plasma terminal complement complex and future risk of venous thromboembolism
J Thromb Haemost, 17 (6), 934-943
DOI 10.1111/jth.14438, PubMed 30920726 -
Targeting the MHC Ligandome by Use of TCR-Like Antibodies
Antibodies (Basel), 8 (2)
DOI 10.3390/antib8020032, PubMed 31544838 -
Local Delivery of Ox40l, Cd80, and Cd86 mRNA Kindles Global Anticancer Immunity
Cancer Res, 79 (7), 1624-1634
DOI 10.1158/0008-5472.CAN-18-2867, PubMed 30692215 -
3D bioprinting of hydrogel constructs with cell and material gradients for the regeneration of full-thickness chondral defect using a microfluidic printing head
Biofabrication, 11 (4), 044101
DOI 10.1088/1758-5090/ab2622, PubMed 31151123 -
Effects of gamma radiation sterilization on the structural and biological properties of decellularized corneal xenografts
Acta Biomater, 96, 330-344
DOI 10.1016/j.actbio.2019.07.002, PubMed 31284096 -
Efficient T cell-B cell collaboration guides autoantibody epitope bias and onset of celiac disease
Proc Natl Acad Sci U S A, 116 (30), 15134-15139
DOI 10.1073/pnas.1901561116, PubMed 31285344 -
IgE-sensitization to food and inhalant allergens in IBD patients compared with normal blood donors at Oslo University Hospital, Norway
Scand J Gastroenterol, 54 (9), 1107-1110
DOI 10.1080/00365521.2019.1663445, PubMed 31524013 -
Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency
Sci Rep, 9 (1), 167 (Retracted)
DOI 10.1038/s41598-018-35367-7, PubMed 30655568 -
Single-Cell RNA Sequencing of In Vitro Expanded Chondrocytes: MSC-Like Cells With No Evidence of Distinct Subsets
Cartilage, 13 (2_suppl), 774S-784S
DOI 10.1177/1947603519847746, PubMed 31072202 -
Robust profiling of microRNAs and isomiRs in human plasma exosomes across 46 individuals
Sci Rep, 9 (1), 19999
DOI 10.1038/s41598-019-56593-7, PubMed 31882820 -
Ocular manifestations of rheumatic diseases
Int Ophthalmol, 40 (2), 503-510
DOI 10.1007/s10792-019-01183-9, PubMed 31583550 -
HLA-DRB3*01:01 exhibits a dose-dependent impact on HPA-1a antibody levels in HPA-1a-immunized women
Blood Adv, 3 (7), 945-951
DOI 10.1182/bloodadvances.2019032227, PubMed 30923048 -
3D bioprinted hydrogel model incorporating β-tricalcium phosphate for calcified cartilage tissue engineering
Biofabrication, 11 (3), 035016
DOI 10.1088/1758-5090/ab15cb, PubMed 30943457 -
Pseudo-anaphylaxis to Polyethylene Glycol (PEG)-Coated Liposomes: Roles of Anti-PEG IgM and Complement Activation in a Porcine Model of Human Infusion Reactions
ACS Nano, 13 (8), 9315-9324
DOI 10.1021/acsnano.9b03942, PubMed 31348638 -
Antibody and DNA sensing pathways converge to activate the inflammasome during primary human macrophage infection
EMBO J, 38 (21), e101365
DOI 10.15252/embj.2018101365, PubMed 31468569 -
Plasma levels of mannose-binding lectin and future risk of venous thromboembolism
J Thromb Haemost, 17 (10), 1661-1669
DOI 10.1111/jth.14539, PubMed 31220397 -
3D cell culture models and organ-on-a-chip: Meet separation science and mass spectrometry
Electrophoresis, 41 (1-2), 56-64
DOI 10.1002/elps.201900170, PubMed 31544246 -
A new method for pharmaceutical compounding and storage of anti-VEGF biologics for intravitreal use in silicone oil-free prefilled plastic syringes
Sci Rep, 9 (1), 18021
DOI 10.1038/s41598-019-54226-7, PubMed 31792234 -
Molecular Profiling Defines Evolutionarily Conserved Transcription Factor Signatures of Major Vestibulospinal Neuron Groups
eNeuro, 6 (1)
DOI 10.1523/ENEURO.0475-18.2019, PubMed 30899776 -
Legumain is upregulated in acute cardiovascular events and associated with improved outcome - potentially related to anti-inflammatory effects on macrophages
Atherosclerosis, 296, 74-82
DOI 10.1016/j.atherosclerosis.2019.12.008, PubMed 31870625 -
Dendritic cell targeted Ccl3- and Xcl1-fusion DNA vaccines differ in induced immune responses and optimal delivery site
Sci Rep, 9 (1), 1820
DOI 10.1038/s41598-018-38080-7, PubMed 30755656 -
Impaired HDL Function Amplifies Systemic Inflammation in Common Variable Immunodeficiency
Sci Rep, 9 (1), 9427
DOI 10.1038/s41598-019-45861-1, PubMed 31263122 -
Functional design of pH-responsive folate-targeted polymer-coated gold nanoparticles for drug delivery and in vivo therapy in breast cancer
Int J Nanomedicine, 14, 8285-8302
DOI 10.2147/IJN.S215142, PubMed 31802866 -
Agaricus blazei-Based Mushroom Extract Supplementation to Birch Allergic Blood Donors: A Randomized Clinical Trial
Nutrients, 11 (10)
DOI 10.3390/nu11102339, PubMed 31581605 -
'Stealth' corporate innovation: an emerging threat for therapeutic drug development
Nat Immunol, 20 (11), 1409-1413
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Author Correction: 'Stealth' corporate innovation: an emerging threat for therapeutic drug development
Nat Immunol, 20 (11), 1556
DOI 10.1038/s41590-019-0531-x, PubMed 31605100 -
The cardiac syndecan-4 interactome reveals a role for syndecan-4 in nuclear translocation of muscle LIM protein (MLP)
J Biol Chem, 294 (22), 8717-8731
DOI 10.1074/jbc.RA118.006423, PubMed 30967474 -
Single-Cell Transcriptomics of Regulatory T Cells Reveals Trajectories of Tissue Adaptation
Immunity, 50 (2), 493-504.e7
DOI 10.1016/j.immuni.2019.01.001, PubMed 30737144 -
Needle-free delivery of DNA: Targeting of hemagglutinin to MHC class II molecules protects rhesus macaques against H1N1 influenza
Vaccine, 37 (6), 817-826
DOI 10.1016/j.vaccine.2018.12.049, PubMed 30638800 -
B cell depletion in the treatment of multiple sclerosis
Expert Opin Biol Ther, 19 (3), 261-271
DOI 10.1080/14712598.2019.1568407, PubMed 30632834 -
Targeting B-cell malignancies with the beta-emitting anti-CD37 radioimmunoconjugate 177Lu-NNV003
Eur J Nucl Med Mol Imaging, 46 (11), 2311-2321
DOI 10.1007/s00259-019-04417-1, PubMed 31309259 -
The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei
Sci Data, 6 (1), 173
DOI 10.1038/s41597-019-0179-2, PubMed 31527615 -
Inhibition of histone methyltransferase DOT1L silences ERα gene and blocks proliferation of antiestrogen-resistant breast cancer cells
Sci Adv, 5 (2), eaav5590
DOI 10.1126/sciadv.aav5590, PubMed 30775443 -
Finding Neo (antigens, that is)
Blood, 134 (2), 108-109
DOI 10.1182/blood.2019001334, PubMed 31296544 -
Biphasic Release of the Alarmin High Mobility Group Box 1 Protein Early After Trauma Predicts Poor Clinical Outcome
Crit Care Med, 47 (8), e614-e622
DOI 10.1097/CCM.0000000000003800, PubMed 31162203 -
Long-range interactions between topologically associating domains shape the four-dimensional genome during differentiation
Nat Genet, 51 (5), 835-843
DOI 10.1038/s41588-019-0392-0, PubMed 31011212 -
Sepsis causes right ventricular myocardial inflammation independent of pulmonary hypertension in a porcine sepsis model
PLoS One, 14 (6), e0218624
DOI 10.1371/journal.pone.0218624, PubMed 31247004 -
Differential Levels and Phosphorylation of Type 1 Inositol 1,4,5-Trisphosphate Receptor in Four Different Murine Models of Huntington Disease
J Huntingtons Dis, 8 (3), 271-289
DOI 10.3233/JHD-180301, PubMed 31256144 -
The Neonatal Fc Receptor (FcRn): A Misnomer?
Front Immunol, 10, 1540
DOI 10.3389/fimmu.2019.01540, PubMed 31354709 -
Two novel HLA-DQ2.5-restricted gluten T cell epitopes in the DQ2.5-glia-γ4 epitope family
Immunogenetics, 71 (10), 665-667
DOI 10.1007/s00251-019-01138-5, PubMed 31673720 -
Mitochondrial stress response triggered by defects in protein synthesis quality control
Life Sci Alliance, 2 (1)
DOI 10.26508/lsa.201800219, PubMed 30683687 -
Growth Mode and Carbon Source Impact the Surfaceome Dynamics of Lactobacillus rhamnosus GG
Front Microbiol, 10, 1272
DOI 10.3389/fmicb.2019.01272, PubMed 31231350 -
Increased Complement Factor B and Bb Levels Are Associated with Mortality in Patients with Severe Aortic Stenosis
J Immunol, 203 (7), 1973-1980
DOI 10.4049/jimmunol.1801244, PubMed 31492744 -
Binding to nanopatterned antigens is dominated by the spatial tolerance of antibodies
Nat Nanotechnol, 14 (2), 184-190
DOI 10.1038/s41565-018-0336-3, PubMed 30643273 -
Publisher Correction: Binding to nanopatterned antigens is dominated by the spatial tolerance of antibodies
Nat Nanotechnol, 14 (4), 398
DOI 10.1038/s41565-019-0404-3, PubMed 30783200 -
Phagocytosis of live and dead Escherichia coli and Staphylococcus aureus in human whole blood is markedly reduced by combined inhibition of C5aR1 and CD14
Mol Immunol, 112, 131-139
DOI 10.1016/j.molimm.2019.03.014, PubMed 31102985 -
An in vitro assay for biomarker discovery and dose prediction applied to ibrutinib plus venetoclax treatment of CLL
Leukemia, 34 (2), 478-487
DOI 10.1038/s41375-019-0569-7, PubMed 31471562 -
Transcriptional profiling of human intestinal plasma cells reveals effector functions beyond antibody production
United European Gastroenterol J, 7 (10), 1399-1407
DOI 10.1177/2050640619862461, PubMed 31839965 -
NLRP3 Inflammasome: A Novel Player in Metabolically Induced Inflammation-Potential Influence on the Myocardium
J Cardiovasc Pharmacol, 74 (4), 276-284
DOI 10.1097/FJC.0000000000000704, PubMed 31584530 -
MEK Inhibition Induces Canonical WNT Signaling through YAP in KRAS Mutated HCT-15 Cells, and a Cancer Preventive FOXO3/FOXM1 Ratio in Combination with TNKS Inhibition
Cancers (Basel), 11 (2)
DOI 10.3390/cancers11020164, PubMed 30717152 -
Update 2020: nomenclature and listing of celiac disease-relevant gluten epitopes recognized by CD4+ T cells
Immunogenetics, 72 (1-2), 85-88
DOI 10.1007/s00251-019-01141-w, PubMed 31735991 -
PML modulates H3.3 targeting to telomeric and centromeric repeats in mouse fibroblasts
Biochem Biophys Res Commun, 511 (4), 882-888
DOI 10.1016/j.bbrc.2019.02.087, PubMed 30850162 -
Impact of humanised isolation and culture conditions on stemness and osteogenic potential of bone marrow derived mesenchymal stromal cells
Sci Rep, 9 (1), 16031
DOI 10.1038/s41598-019-52442-9, PubMed 31690774 -
A Wide Spectrum of Ocular Manifestations Signify Patients with Systemic Sclerosis
Ocul Immunol Inflamm, 29 (1), 81-89
DOI 10.1080/09273948.2019.1657467, PubMed 31577461 -
Maternal microchimerism in cord blood and risk of childhood-onset type 1 diabetes
Pediatr Diabetes, 20 (6), 728-735
DOI 10.1111/pedi.12875, PubMed 31173445 -
Maternal and Newborn Vitamin D-Binding Protein, Vitamin D Levels, Vitamin D Receptor Genotype, and Childhood Type 1 Diabetes
Diabetes Care, 42 (4), 553-559
DOI 10.2337/dc18-2176, PubMed 30692241 -
Targeting Conventional Dendritic Cells to Fine-Tune Antibody Responses
Front Immunol, 10, 1529
DOI 10.3389/fimmu.2019.01529, PubMed 31333661 -
Complement Component C5 and TLR Molecule CD14 Mediate Heme-Induced Thromboinflammation in Human Blood
J Immunol, 203 (6), 1571-1578
DOI 10.4049/jimmunol.1900047, PubMed 31413105 -
The Role of Complement in Liver Injury, Regeneration, and Transplantation
Hepatology, 70 (2), 725-736
DOI 10.1002/hep.30508, PubMed 30653682 -
Fetal and neonatal alloimmune thrombocytopenia - The Norwegian management model
Transfus Apher Sci, 59 (1), 102711
DOI 10.1016/j.transci.2019.102711, PubMed 31911047 -
Persistence of intrathecal oligoclonal B cells and IgG in multiple sclerosis
J Neuroimmunol, 333, 576966
DOI 10.1016/j.jneuroim.2019.576966, PubMed 31153015 -
Cytokine release after gluten ingestion differentiates coeliac disease from self-reported gluten sensitivity
United European Gastroenterol J, 8 (1), 108-118
DOI 10.1177/2050640619874173, PubMed 32213060 -
Low Cellular NAD+ Compromises Lipopolysaccharide-Induced Inflammatory Responses via Inhibiting TLR4 Signal Transduction in Human Monocytes
J Immunol, 203 (6), 1598-1608
DOI 10.4049/jimmunol.1801382, PubMed 31427442 -
Evaluating plasma extracellular vesicle microRNAs as possible biomarkers for osteoarthritis
Osteoarthr Cartil Open, 1 (3-4), 100018
DOI 10.1016/j.ocarto.2019.100018, PubMed 36475003
Publications 2018
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Polarity of CD4+ T cells towards the antigen presenting cell is regulated by the Lck adapter TSAd
Sci Rep, 8 (1), 13319
DOI 10.1038/s41598-018-31510-6, PubMed 30190583 -
Pediatric red cell and platelet transfusions
Transfus Apher Sci, 57 (3), 358-362
DOI 10.1016/j.transci.2018.05.019, PubMed 29804934 -
Immunohematologic issues in ABO-incompatible allogeneic hematopoietic stem cell transplantation
Transfus Apher Sci, 57 (6), 812-815
DOI 10.1016/j.transci.2018.10.020, PubMed 30404742 -
Simultaneous Targeting of Multiple Hemagglutinins to APCs for Induction of Broad Immunity against Influenza
J Immunol, 200 (6), 2057-2066
DOI 10.4049/jimmunol.1701088, PubMed 29427414 -
Staphylococcus aureus Membrane-Derived Vesicles Promote Bacterial Virulence and Confer Protective Immunity in Murine Infection Models
Front Microbiol, 9, 262
DOI 10.3389/fmicb.2018.00262, PubMed 29515544 -
Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses
Nat Immunol, 19 (7), 776-786
DOI 10.1038/s41590-018-0121-3, PubMed 29784908 -
A Case of Posttransfusion Purpura with Severe Refractory Thrombocytopenia but No Cutaneous Manifestations
Case Rep Hematol, 2018, 8187659
DOI 10.1155/2018/8187659, PubMed 30510818 -
Crystal structure of an L chain optimised 14F7 anti-ganglioside Fv suggests a unique tumour-specificity through an unusual H-chain CDR3 architecture
Sci Rep, 8 (1), 10836
DOI 10.1038/s41598-018-28918-5, PubMed 30022069 -
Inflammation and Mechanical Stress Stimulate Osteogenic Differentiation of Human Aortic Valve Interstitial Cells
Front Physiol, 9, 1635
DOI 10.3389/fphys.2018.01635, PubMed 30524301 -
TRIM21 mediates antibody inhibition of adenovirus-based gene delivery and vaccination
Proc Natl Acad Sci U S A, 115 (41), 10440-10445
DOI 10.1073/pnas.1806314115, PubMed 30209217 -
Lamin A, Chromatin and FPLD2: Not Just a Peripheral Ménage-à-Trois
Front Cell Dev Biol, 6, 73
DOI 10.3389/fcell.2018.00073, PubMed 30057899 -
Laminopathy-causing lamin A mutations reconfigure lamina-associated domains and local spatial chromatin conformation
Nucleus, 9 (1), 216-226
DOI 10.1080/19491034.2018.1449498, PubMed 29517398 -
The lipodystrophic hotspot lamin A p.R482W mutation deregulates the mesodermal inducer T/Brachyury and early vascular differentiation gene networks
Hum Mol Genet, 27 (8), 1447-1459
DOI 10.1093/hmg/ddy055, PubMed 29438482 -
Lipophilic components of diesel exhaust particles induce pro-inflammatory responses in human endothelial cells through AhR dependent pathway(s)
Part Fibre Toxicol, 15 (1), 21
DOI 10.1186/s12989-018-0257-1, PubMed 29751765 -
The Magnitude and IgG Subclass of Antibodies Elicited by Targeted DNA Vaccines Are Influenced by Specificity for APC Surface Molecules
Immunohorizons, 2 (1), 38-53
DOI 10.4049/immunohorizons.1700038, PubMed 31022690 -
Important to distinguish intermediate from intensive care patients
Tidsskr. Nor. Laegeforen., 138 (11), 993-994 -
Cytokine profiles and diagnoses in elderly, hospitalized psychiatric patients
BMC Psychiatry, 18 (1), 315
DOI 10.1186/s12888-018-1900-y, PubMed 30261848 -
From Inflammasome to Exosome-Does Extracellular Vesicle Secretion Constitute an Inflammasome-Dependent Immune Response?
Front Immunol, 9, 2188
DOI 10.3389/fimmu.2018.02188, PubMed 30319640 -
Discriminative T-cell receptor recognition of highly homologous HLA-DQ2-bound gluten epitopes
J Biol Chem, 294 (3), 941-952
DOI 10.1074/jbc.RA118.005736, PubMed 30455354 -
Identification of MHC Class Ib Ligands for Stimulatory and Inhibitory Ly49 Receptors and Induction of Potent NK Cell Alloresponses in Rats
J Immunol, 200 (8), 2847-2859
DOI 10.4049/jimmunol.1701464, PubMed 29531166 -
High-resolution antibody array analysis of proteins from primary human keratinocytes and leukocytes
PLoS One, 13 (12), e0209271
DOI 10.1371/journal.pone.0209271, PubMed 30589857 -
Microthrombotic renal involvement in an SLE patient with concomitant catastrophic antiphospholipid syndrome: the beneficial effect of rituximab treatment
Lupus, 27 (9), 1552-1558
DOI 10.1177/0961203318768890, PubMed 29635999 -
Monocytes accumulate in the airways of children with fatal asthma
Clin Exp Allergy, 48 (12), 1631-1639
DOI 10.1111/cea.13265, PubMed 30184280 -
Tumor Killing by CD4+ T Cells Is Mediated via Induction of Inducible Nitric Oxide Synthase-Dependent Macrophage Cytotoxicity
Front Immunol, 9, 1684
DOI 10.3389/fimmu.2018.01684, PubMed 30083157 -
Normal development of mice lacking PAXX, the paralogue of XRCC4 and XLF
FEBS Open Bio, 8 (3), 426-434
DOI 10.1002/2211-5463.12381, PubMed 29511619 -
Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population
Front Immunol, 9, 2664
DOI 10.3389/fimmu.2018.02664, PubMed 30515158 -
Quantitative mapping of RNA-mediated nuclear estrogen receptor β interactome in human breast cancer cells
Sci Data, 5, 180031
DOI 10.1038/sdata.2018.31, PubMed 29509190 -
Wilhelm His' lasting insights into hindbrain and cranial ganglia development and evolution
Dev Biol, 444 Suppl 1 (Suppl 1), S14-S24
DOI 10.1016/j.ydbio.2018.02.001, PubMed 29447907 -
A human endothelial cell-based recycling assay for screening of FcRn targeted molecules
Nat Commun, 9 (1), 621
DOI 10.1038/s41467-018-03061-x, PubMed 29434196 -
Corneal Involvement of Patients with Polymyositis and Dermatomyositis
Ocul Immunol Inflamm, 28 (1), 58-66
DOI 10.1080/09273948.2018.1547407, PubMed 30444429 -
Lack of Association among Peptidyl Arginine Deiminase Type 4 Autoantibodies, PADI4 Polymorphisms, and Clinical Characteristics in Rheumatoid Arthritis
J Rheumatol, 45 (9), 1211-1219
DOI 10.3899/jrheum.170769, PubMed 29858238 -
Soluble T-cell receptor design influences functional yield in an E. coli chaperone-assisted expression system
PLoS One, 13 (4), e0195868
DOI 10.1371/journal.pone.0195868, PubMed 29649333 -
Exploration of 27 plasma immune markers: a cross-sectional comparison of 64 old psychiatric inpatients having unipolar major depression and 18 non-depressed old persons
BMC Geriatr, 18 (1), 149
DOI 10.1186/s12877-018-0836-x, PubMed 29940870 -
The Palliative Radiotherapy and Inflammation Study (PRAIS) - protocol for a longitudinal observational multicenter study on patients with cancer induced bone pain
BMC Palliat Care, 17 (1), 110
DOI 10.1186/s12904-018-0362-9, PubMed 30266081 -
Granulocyte and monocyte CD11b expression during plasma separation is dependent on complement factor 5 (C5) - an ex vivo study with blood from a C5-deficient individual
APMIS, 126 (4), 342-352
DOI 10.1111/apm.12821, PubMed 29575196 -
Cryopreservation of primary B cells minimally influences their signaling responses
Sci Rep, 8 (1), 17651
DOI 10.1038/s41598-018-36121-9, PubMed 30518828 -
Associations between complement pathways activity, mannose-binding lectin, and odds of unprovoked venous thromboembolism
Thromb Res, 169, 50-56
DOI 10.1016/j.thromres.2018.06.019, PubMed 30015228 -
Plasma Cells Are the Most Abundant Gluten Peptide MHC-expressing Cells in Inflamed Intestinal Tissues From Patients With Celiac Disease
Gastroenterology, 156 (5), 1428-1439.e10
DOI 10.1053/j.gastro.2018.12.013, PubMed 30593798 -
mRNA vaccination with charge-altering releasable transporters elicits human T cell responses and cures established tumors in mice
Proc Natl Acad Sci U S A, 115 (39), E9153-E9161
DOI 10.1073/pnas.1810002115, PubMed 30201728 -
CD4+ T-cell-Mediated Rejection of MHC Class II-Positive Tumor Cells Is Dependent on Antigen Secretion and Indirect Presentation on Host APCs
Cancer Res, 78 (16), 4573-4585
DOI 10.1158/0008-5472.CAN-17-2426, PubMed 29752262 -
One-step generation of monoclonal B cell receptor mice capable of isotype switching and somatic hypermutation
J Exp Med, 215 (10), 2686-2695
DOI 10.1084/jem.20172064, PubMed 30181412 -
Expression of inflammatory cytokines in mesenchymal stromal cells is sensitive to culture conditions and simple cell manipulations
Exp Cell Res, 374 (1), 122-127
DOI 10.1016/j.yexcr.2018.11.014, PubMed 30496759 -
Uhrf1 regulates active transcriptional marks at bivalent domains in pluripotent stem cells through Setd1a
Nat Commun, 9 (1), 2583
DOI 10.1038/s41467-018-04818-0, PubMed 29968706 -
Interleukin-6 receptor inhibition with tocilizumab induces a selective and substantial increase in plasma IP-10 and MIP-1β in non-ST-elevation myocardial infarction
Int J Cardiol, 271, 1-7
DOI 10.1016/j.ijcard.2018.04.136, PubMed 29961572 -
Locomotor central pattern generator excitability states and serotonin sensitivity after spontaneous recovery from a neonatal lumbar spinal cord injury
Brain Res, 1708, 10-19
DOI 10.1016/j.brainres.2018.12.001, PubMed 30521786 -
Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Controls Fibroblast Growth Factor Receptor (FGFR) 1 Activity and Influences Sensitivity to FGFR Kinase Inhibitors
Mol Cell Proteomics, 17 (5), 850-870
DOI 10.1074/mcp.RA117.000538, PubMed 29371290 -
HLA -A, -C, -B, -DRB1, -DQB1 and -DPB1 allele and haplotype frequencies in 4514 healthy Norwegians
Hum Immunol, 79 (7), 527-529
DOI 10.1016/j.humimm.2018.04.012, PubMed 29684411 -
Complement component 5 does not interfere with physiological hemostasis but is essential for Escherichia coli-induced coagulation accompanied by Toll-like receptor 4
Clin Exp Immunol, 196 (1), 97-110
DOI 10.1111/cei.13240, PubMed 30444525 -
BraCeR: B-cell-receptor reconstruction and clonality inference from single-cell RNA-seq
Nat Methods, 15 (8), 563-565
DOI 10.1038/s41592-018-0082-3, PubMed 30065371 -
Advances in stem cell therapy for amyotrophic lateral sclerosis
Expert Opin Biol Ther, 18 (8), 865-881
DOI 10.1080/14712598.2018.1503248, PubMed 30025485 -
Minimal residual disease quantification by flow cytometry provides reliable risk stratification in T-cell acute lymphoblastic leukemia
Leukemia, 33 (6), 1324-1336
DOI 10.1038/s41375-018-0307-6, PubMed 30552401 -
Patterns of Invasive Growth in Malignant Gliomas-The Hippocampus Emerges as an Invasion-Spared Brain Region
Neoplasia, 20 (7), 643-656
DOI 10.1016/j.neo.2018.04.001, PubMed 29793116 -
Single cell profiling of phospho-protein levels in chronic lymphocytic leukemia
Oncotarget, 9 (10), 9273-9284
DOI 10.18632/oncotarget.23949, PubMed 29507689 -
Corneal Manifestations of Systemic Sclerosis
Ocul Immunol Inflamm, 27 (6), 968-977
DOI 10.1080/09273948.2018.1489556, PubMed 30015530 -
Splicing of platelet resident pre-mRNAs upon activation by physiological stimuli results in functionally relevant proteome modifications
Sci Rep, 8 (1), 498
DOI 10.1038/s41598-017-18985-5, PubMed 29323256 -
Human and mouse albumin bind their respective neonatal Fc receptors differently
Sci Rep, 8 (1), 14648
DOI 10.1038/s41598-018-32817-0, PubMed 30279529 -
Animal models for evaluation of albumin-based therapeutics
Curr. Opin. Chem. Eng., 19, 68-76
DOI 10.1016/j.coche.2017.11.007 -
Donor health assessment - When is blood donation safe?
Transfus Apher Sci, 58 (1), 113-116
DOI 10.1016/j.transci.2018.12.016, PubMed 30630765 -
The tankyrase inhibitor G007-LK inhibits small intestine LGR5+ stem cell proliferation without altering tissue morphology
Biol Res, 51 (1), 3
DOI 10.1186/s40659-017-0151-6, PubMed 29316982 -
Acute heart failure following myocardial infarction: complement activation correlates with the severity of heart failure in patients developing cardiogenic shock
ESC Heart Fail, 5 (3), 292-301
DOI 10.1002/ehf2.12266, PubMed 29424484 -
IL-6 Receptor Inhibition by Tocilizumab Attenuated Expression of C5a Receptor 1 and 2 in Non-ST-Elevation Myocardial Infarction
Front Immunol, 9, 2035
DOI 10.3389/fimmu.2018.02035, PubMed 30258440 -
Soluble IL-1 receptor 2 is associated with left ventricular remodelling in patients with ST-elevation myocardial infarction
Int J Cardiol, 268, 187-192
DOI 10.1016/j.ijcard.2018.05.032, PubMed 29853279 -
Current use of biosimilar G-CSF for haematopoietic stem cell mobilisation
Bone Marrow Transplant, 54 (6), 858-866
DOI 10.1038/s41409-018-0350-y, PubMed 30283148 -
Predictors of chronic fatigue in adolescents six months after acute Epstein-Barr virus infection: A prospective cohort study
Brain Behav Immun, 75, 94-100
DOI 10.1016/j.bbi.2018.09.023, PubMed 30261303 -
Directed reprogramming of comprehensively characterized dental pulp stem cells extracted from natal tooth
Sci Rep, 8 (1), 6168
DOI 10.1038/s41598-018-24421-z, PubMed 29670257 -
High neopterin and IP-10 levels in cerebrospinal fluid are associated with neurotoxic tryptophan metabolites in acute central nervous system infections
J Neuroinflammation, 15 (1), 327
DOI 10.1186/s12974-018-1366-3, PubMed 30470234 -
Recellularization of Decellularized Venous Grafts Using Peripheral Blood: A Critical Evaluation
EBioMedicine, 32, 215-222
DOI 10.1016/j.ebiom.2018.05.012, PubMed 29779699 -
Disease-driving CD4+ T cell clonotypes persist for decades in celiac disease
J Clin Invest, 128 (6), 2642-2650
DOI 10.1172/JCI98819, PubMed 29757191 -
The SysteMHC Atlas project
Nucleic Acids Res, 46 (D1), D1237-D1247
DOI 10.1093/nar/gkx664, PubMed 28985418 -
A high-throughput pipeline for validation of antibodies
Nat Methods, 15 (11), 909-912
DOI 10.1038/s41592-018-0179-8, PubMed 30377371 -
Low Levels of Immunoglobulins and Mannose-Binding Lectin Are Not Associated With Etiology, Severity, or Outcome in Community-Acquired Pneumonia
Open Forum Infect Dis, 5 (2), ofy002
DOI 10.1093/ofid/ofy002, PubMed 29410975 -
Pharmaceutical compounding of aflibercept in prefilled syringes does not affect structural integrity, stability or VEGF and Fc binding properties
Sci Rep, 8 (1), 2101
DOI 10.1038/s41598-018-20525-8, PubMed 29391560 -
Staphylococcus aureus-induced complement activation promotes tissue factor-mediated coagulation
J Thromb Haemost, 16 (5), 905-918
DOI 10.1111/jth.13979, PubMed 29437288 -
Dystonia-deafness syndrome caused by ACTB p.Arg183Trp heterozygosity shows striatal dopaminergic dysfunction and response to pallidal stimulation
J Neurodev Disord, 10 (1), 17
DOI 10.1186/s11689-018-9235-z, PubMed 29788902 -
Ultracentrifugation versus kit exosome isolation: nanoLC-MS and other tools reveal similar performance biomarkers, but also contaminations
Future Sci OA, 5 (1), FSO359
DOI 10.4155/fsoa-2018-0088, PubMed 30652024 -
C-C Motif Ligand 20 (CCL20) and C-C Motif Chemokine Receptor 6 (CCR6) in Human Peripheral Blood Mononuclear Cells: Dysregulated in Ulcerative Colitis and a Potential Role for CCL20 in IL-1β Release
Int J Mol Sci, 19 (10)
DOI 10.3390/ijms19103257, PubMed 30347808 -
Human IgG lacking effector functions demonstrate lower FcRn-binding and reduced transplacental transport
Mol Immunol, 95, 1-9
DOI 10.1016/j.molimm.2018.01.006, PubMed 29367080 -
Prenatal iron exposure and childhood type 1 diabetes
Sci Rep, 8 (1), 9067
DOI 10.1038/s41598-018-27391-4, PubMed 29899542 -
[A ban on energy drinks?]
Tidsskr Nor Laegeforen, 138 (17)
DOI 10.4045/tidsskr.18.0773, PubMed 30378415 -
Effect of Genetic and Laboratory Findings on Clinical Course of Antisynthetase Syndrome in a Hungarian Cohort
Biomed Res Int, 2018, 6416378
DOI 10.1155/2018/6416378, PubMed 30498759 -
Determination of fetal RHD type in plasma of RhD negative pregnant women
Scand J Clin Lab Invest, 78 (5), 411-416
DOI 10.1080/00365513.2018.1475681, PubMed 29869532 -
Combined Inhibition of C5 and CD14 Attenuates Systemic Inflammation in a Piglet Model of Meconium Aspiration Syndrome
Neonatology, 113 (4), 322-330
DOI 10.1159/000486542, PubMed 29486477 -
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for pseudomyxoma peritonei in a liver-transplanted patient: a case report
World J Surg Oncol, 16 (1), 180
DOI 10.1186/s12957-018-1482-7, PubMed 30185175 -
G1m1 predominance of intrathecal virus-specific antibodies in multiple sclerosis
Ann Clin Transl Neurol, 5 (10), 1303-1309
DOI 10.1002/acn3.642, PubMed 30349866 -
Characterization of the Small Intestinal Lesion in Celiac Disease by Label-Free Quantitative Mass Spectrometry
Am J Pathol, 188 (7), 1563-1579
DOI 10.1016/j.ajpath.2018.03.017, PubMed 29684362 -
Ribosomal DNA copy loss and repeat instability in ATRX-mutated cancers
Proc Natl Acad Sci U S A, 115 (18), 4737-4742
DOI 10.1073/pnas.1720391115, PubMed 29669917 -
Addressing Ethical and Procedural Principles for Unrelated Allogeneic Hematopoietic Progenitor Cell Donation in a Changing Medical Environment
Biol Blood Marrow Transplant, 24 (5), 887-894
DOI 10.1016/j.bbmt.2018.01.018, PubMed 29410372 -
Congratulations on your study choice!
Tidsskr. Nor. Laegeforen., 138 (12), 1201 -
Cytokine profiling and post-transfusion haemoglobin increment in patients with haematological diseases
Vox Sang, 113 (7), 657-668
DOI 10.1111/vox.12703, PubMed 30159896 -
Iron oxide nanoparticles enhance Toll-like receptor-induced cytokines in a particle size- and actin-dependent manner in human blood
Nanomedicine (Lond), 13 (14), 1773-1785
DOI 10.2217/nnm-2017-0362, PubMed 30084726
Publications 2017
-
A DNA Vaccine That Targets Hemagglutinin to Antigen-Presenting Cells Protects Mice against H7 Influenza
J Virol, 91 (23)
DOI 10.1128/JVI.01340-17, PubMed 28931687 -
Discovery of a Novel Series of Tankyrase Inhibitors by a Hybridization Approach
J Med Chem, 60 (24), 10013-10025
DOI 10.1021/acs.jmedchem.7b00883, PubMed 29155568 -
Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation
J Immunol, 199 (8), 2910-2920
DOI 10.4049/jimmunol.1700302, PubMed 28855312 -
Identification and characterization of a new source of adult human neural progenitors
Cell Death Dis, 8 (8), e2991
DOI 10.1038/cddis.2017.368, PubMed 28796246 -
Rat acute GvHD is Th1 driven and characterized by predominant donor CD4+ T-cell infiltration of skin and gut
Exp Hematol, 50, 33-45.e3
DOI 10.1016/j.exphem.2017.02.002, PubMed 28238806 -
IL-12, IL-15, and IL-18 pre-activated NK cells target resistant T cell acute lymphoblastic leukemia and delay leukemia development in vivo
Oncoimmunology, 6 (3), e1274478
DOI 10.1080/2162402X.2016.1274478, PubMed 28405496 -
Corrigendum: Antibody-antigen kinetics constrain intracellular humoral immunity
Sci Rep, 7, 45418
DOI 10.1038/srep45418, PubMed 28382939 -
Polysaccharides from the South African medicinal plant Artemisia afra: Structure and activity studies
Fitoterapia, 124, 182-187
DOI 10.1016/j.fitote.2017.11.016, PubMed 29155274 -
Traceability and distribution of Neisseria meningitidis DNA in archived post mortem tissue samples from patients with systemic meningococcal disease
BMC Clin Pathol, 17, 10
DOI 10.1186/s12907-017-0049-9, PubMed 28824331 -
Transcriptional and functional profiling defines human small intestinal macrophage subsets
J Exp Med, 215 (2), 441-458
DOI 10.1084/jem.20170057, PubMed 29273642 -
Sensing External and Self-Motion with Hair Cells: A Comparison of the Lateral Line and Vestibular Systems from a Developmental and Evolutionary Perspective
Brain Behav Evol, 90 (2), 98-116
DOI 10.1159/000456646, PubMed 28988233 -
Cellular reactions and compensatory tissue re-organization during spontaneous recovery after spinal cord injury in neonatal mice
Dev Neurobiol, 77 (8), 928-946
DOI 10.1002/dneu.22479, PubMed 28033684 -
MicroRNA expression profiles identify disease-specific alterations in systemic lupus erythematosus and primary Sjögren's syndrome
PLoS One, 12 (3), e0174585
DOI 10.1371/journal.pone.0174585, PubMed 28339495 -
Unraveling the role of maternal anti-HLA class I antibodies in fetal and neonatal thrombocytopenia-Antibody specificity analysis using epitope data
J Reprod Immunol, 122, 1-9
DOI 10.1016/j.jri.2017.06.003, PubMed 28686909 -
Association Between Pretransplant Cancer and Survival in Kidney Transplant Recipients
Transplantation, 101 (10), 2599-2605
DOI 10.1097/TP.0000000000001659, PubMed 28207636 -
The anti-influenza M2e antibody response is promoted by XCR1 targeting in pig skin
Sci Rep, 7 (1), 7639
DOI 10.1038/s41598-017-07372-9, PubMed 28794452 -
The Regulatory Role of the Oral Commensal Streptococcus mitis on Human Monocytes
Scand J Immunol, 87 (2), 80-87
DOI 10.1111/sji.12636, PubMed 29194752 -
Germinal Center Selection and Affinity Maturation Require Dynamic Regulation of mTORC1 Kinase
Immunity, 46 (6), 1045-1058.e6
DOI 10.1016/j.immuni.2017.06.005, PubMed 28636954 -
Tissue factor pathway inhibitor attenuates ER stress-induced inflammation in human M2-polarized macrophages
Biochem Biophys Res Commun, 491 (2), 442-448
DOI 10.1016/j.bbrc.2017.07.070, PubMed 28712870 -
Reduced inflammatory response by transcatheter, as compared to surgical aortic valve replacement
Scand Cardiovasc J, 52 (1), 43-50
DOI 10.1080/14017431.2017.1416157, PubMed 29233022 -
Low-dose acetaminophen induces early disruption of cell-cell tight junctions in human hepatic cells and mouse liver
Sci Rep, 7, 37541
DOI 10.1038/srep37541, PubMed 28134251 -
Ficolins do not alter host immune responses to lipopolysaccharide-induced inflammation in vivo
Sci Rep, 7 (1), 3852
DOI 10.1038/s41598-017-04121-w, PubMed 28634324 -
Epitope-specific immunotherapy targeting CD4-positive T cells in coeliac disease: two randomised, double-blind, placebo-controlled phase 1 studies
Lancet Gastroenterol Hepatol, 2 (7), 479-493
DOI 10.1016/S2468-1253(17)30110-3, PubMed 28506538 -
Alginate microbeads are coagulation compatible, while alginate microcapsules activate coagulation secondary to complement or directly through FXII
Acta Biomater, 58, 158-167
DOI 10.1016/j.actbio.2017.05.052, PubMed 28576714 -
Targeting Influenza Virus Hemagglutinin to Xcr1+ Dendritic Cells in the Absence of Receptor-Mediated Endocytosis Enhances Protective Antibody Responses
J Immunol, 198 (7), 2785-2795
DOI 10.4049/jimmunol.1601881, PubMed 28228559 -
A TCRα framework-centered codon shapes a biased T cell repertoire through direct MHC and CDR3β interactions
JCI Insight, 2 (17)
DOI 10.1172/jci.insight.95193, PubMed 28878121 -
Effect on mother and child of eculizumab given before caesarean section in a patient with severe antiphospholipid syndrome: A case report
Medicine (Baltimore), 96 (11), e6338
DOI 10.1097/MD.0000000000006338, PubMed 28296762 -
A Nonadjuvanted IgG2a Monoclonal Antibody against Nucleosomes Elicits Potent T Cell-Dependent, Idiotype-Specific IgG1 Responses and Glomerular IgG1/IgG2a Deposits in Normal Mice
J Immunol, 199 (2), 489-500
DOI 10.4049/jimmunol.1600718, PubMed 28592426 -
Properdin binding to complement activating surfaces depends on initial C3b deposition
Proc Natl Acad Sci U S A, 114 (4), E534-E539
DOI 10.1073/pnas.1612385114, PubMed 28069958 -
The proteome of pus from human brain abscesses: host-derived neurotoxic proteins and the cell-type diversity of CNS pus
J Neurosurg, 129 (3), 829-837
DOI 10.3171/2017.4.JNS17284, PubMed 29053067 -
Blood rejuvenation and the goal of medicine
Tidsskr. Nor. Laegeforen., 137 (20), 1575 -
Combined inhibition of C5 and CD14 efficiently attenuated the inflammatory response in a porcine model of meningococcal sepsis
J Intensive Care, 5, 21
DOI 10.1186/s40560-017-0217-0, PubMed 28261486 -
Effect of the anticoagulant, storage time and temperature of blood samples on the concentrations of 27 multiplex assayed cytokines - Consequences for defining reference values in healthy humans
Cytokine, 97, 86-95
DOI 10.1016/j.cyto.2017.05.014, PubMed 28595117 -
HLA haplotypes in primary sclerosing cholangitis patients of admixed and non-European ancestry
HLA, 90 (4), 228-233
DOI 10.1111/tan.13076, PubMed 28695657 -
Cardiopulmonary Disease Development in Anti-RNA Polymerase III-positive Systemic Sclerosis: Comparative Analyses from an Unselected, Prospective Patient Cohort
J Rheumatol, 44 (4), 459-465
DOI 10.3899/jrheum.160867, PubMed 28089974 -
In Silico Prediction Analysis of Idiotope-Driven T-B Cell Collaboration in Multiple Sclerosis
Front Immunol, 8, 1255
DOI 10.3389/fimmu.2017.01255, PubMed 29038659 -
Strong Clonal Relatedness between Serum and Gut IgA despite Different Plasma Cell Origins
Cell Rep, 20 (10), 2357-2367
DOI 10.1016/j.celrep.2017.08.036, PubMed 28877470 -
T Cells in Celiac Disease
J Immunol, 198 (8), 3005-3014
DOI 10.4049/jimmunol.1601693, PubMed 28373482 -
Do Long-Lived Plasma Cells Maintain a Healthy Microbiota in the Gut?
Trends Immunol, 39 (3), 196-208
DOI 10.1016/j.it.2017.10.006, PubMed 29162322 -
Programmed cell death as a defence against infection
Nat Rev Immunol, 17 (3), 151-164
DOI 10.1038/nri.2016.147, PubMed 28138137 -
Inhibition of complement C5 protects against organ failure and reduces mortality in a baboon model of Escherichia coli sepsis
Proc Natl Acad Sci U S A, 114 (31), E6390-E6399
DOI 10.1073/pnas.1706818114, PubMed 28720697 -
Portal vein reconstruction using primary anastomosis or venous interposition allograft in pancreatic surgery
J Vasc Surg Venous Lymphat Disord, 6 (1), 66-74
DOI 10.1016/j.jvsv.2017.09.003, PubMed 29128301 -
Scandiatransplant acceptable mismatch program (STAMP) a bridge to transplanting highly immunized patients
HLA, 90 (1), 17-24
DOI 10.1111/tan.13046, PubMed 28449350 -
A tool for integrating genetic and mass spectrometry-based peptide data: Proteogenomics Viewer: PV: A genome browser-like tool, which includes MS data visualization and peptide identification parameters
Bioessays, 39 (7)
DOI 10.1002/bies.201700015, PubMed 28582591 -
Antibody-secreting plasma cells persist for decades in human intestine
J Exp Med, 214 (2), 309-317
DOI 10.1084/jem.20161590, PubMed 28104812 -
Global Characterization of Protein Secretion from Human Macrophages Following Non-canonical Caspase-4/5 Inflammasome Activation
Mol Cell Proteomics, 16 (4 suppl 1), S187-S199
DOI 10.1074/mcp.M116.064840, PubMed 28196878 -
Selective intrathecal enrichment of G1m1-positive B cells in multiple sclerosis
Ann Clin Transl Neurol, 4 (10), 756-761
DOI 10.1002/acn3.451, PubMed 29046884 -
Mapping the in vitro interactome of cardiac sodium (Na+ )-calcium (Ca2+ ) exchanger 1 (NCX1)
Proteomics, 17 (17-18)
DOI 10.1002/pmic.201600417, PubMed 28755400 -
Should we ignore western blots when selecting antibodies for other applications?
Nat Methods, 14 (3), 215
DOI 10.1038/nmeth.4192, PubMed 28245212 -
5-FU resistant EMT-like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin
J Exp Clin Cancer Res, 36 (1), 187
DOI 10.1186/s13046-017-0662-6, PubMed 29258566 -
Immunohistology and remodeling in fatal pediatric and adolescent asthma
Respir Res, 18 (1), 94
DOI 10.1186/s12931-017-0575-0, PubMed 28511697 -
iNOS- and NOX1-dependent ROS production maintains bacterial homeostasis in the ileum of mice
Mucosal Immunol, 11 (3), 774-784
DOI 10.1038/mi.2017.106, PubMed 29210363 -
Biomarkers for rheumatoid arthritis: From molecular processes to diagnostic applications-current concepts and future perspectives
Immunol Lett, 189, 13-18
DOI 10.1016/j.imlet.2017.05.010, PubMed 28526580 -
Unraveling the structural basis for the unusually rich association of human leukocyte antigen DQ2.5 with class-II-associated invariant chain peptides
J Biol Chem, 292 (22), 9218-9228
DOI 10.1074/jbc.M117.785139, PubMed 28364043 -
Eculizumab-C5 complexes express a C5a neoepitope in vivo: Consequences for interpretation of patient complement analyses
Mol Immunol, 89, 111-114
DOI 10.1016/j.molimm.2017.05.021, PubMed 28610663 -
Mass spectrometry-based proteomic exploration of the human immune system: focus on the inflammasome, global protein secretion, and T cells
Expert Rev Proteomics, 14 (5), 395-407
DOI 10.1080/14789450.2017.1319768, PubMed 28406322 -
Proteomics to study macrophage response to viral infection
J Proteomics, 180, 99-107
DOI 10.1016/j.jprot.2017.06.018, PubMed 28647517 -
Regulatory immune cells and functions in autoimmunity and transplantation immunology
Autoimmun Rev, 16 (5), 435-444
DOI 10.1016/j.autrev.2017.03.011, PubMed 28286106 -
Cyclized Oligopeptide Targeting LRP5/6-DKK1 Interaction Reduces the Growth of Tumor Burden in a Multiple Myeloma Mouse Model
Yonsei Med J, 58 (3), 505-513
DOI 10.3349/ymj.2017.58.3.505, PubMed 28332354 -
Glomerular abundance of complement proteins characterized by proteomic analysis of laser-captured microdissected glomeruli associates with progressive disease in IgA nephropathy
Clin Proteomics, 14, 30
DOI 10.1186/s12014-017-9165-x, PubMed 28814945 -
Complement factor 5 blockade reduces porcine myocardial infarction size and improves immediate cardiac function
Basic Res Cardiol, 112 (3), 20
DOI 10.1007/s00395-017-0610-9, PubMed 28258298 -
Juvenile myasthenia gravis in Norway: HLA-DRB1*04:04 is positively associated with prepubertal onset
PLoS One, 12 (10), e0186383
DOI 10.1371/journal.pone.0186383, PubMed 29036181 -
Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury
Proc Natl Acad Sci U S A, 114 (14), E2862-E2871
DOI 10.1073/pnas.1618291114, PubMed 28330995 -
Similar Responses of Intestinal T Cells From Untreated Children and Adults With Celiac Disease to Deamidated Gluten Epitopes
Gastroenterology, 153 (3), 787-798.e4
DOI 10.1053/j.gastro.2017.05.016, PubMed 28535873 -
Evaluation of commonly used tear sampling methods and their relevance in subsequent biochemical analysis
Ann Clin Biochem, 54 (5), 521-529
DOI 10.1177/0004563217695843, PubMed 28193107 -
Association between objective signs and subjective symptoms of dry eye disease in patients with systemic sclerosis
Rheumatol Int, 37 (11), 1835-1845
DOI 10.1007/s00296-017-3794-2, PubMed 28884335 -
Complement in clinical medicine: Clinical trials, case reports and therapy monitoring
Mol Immunol, 89, 10-21
DOI 10.1016/j.molimm.2017.05.013, PubMed 28576323 -
High-Throughput Single-Cell Analysis of B Cell Receptor Usage among Autoantigen-Specific Plasma Cells in Celiac Disease
J Immunol, 199 (2), 782-791
DOI 10.4049/jimmunol.1700169, PubMed 28600290 -
Valve Interstitial Cells: The Key to Understanding the Pathophysiology of Heart Valve Calcification
J Am Heart Assoc, 6 (9)
DOI 10.1161/JAHA.117.006339, PubMed 28912209 -
HLA-DQ-Gluten Tetramer Blood Test Accurately Identifies Patients With and Without Celiac Disease in Absence of Gluten Consumption
Gastroenterology, 154 (4), 886-896.e6
DOI 10.1053/j.gastro.2017.11.006, PubMed 29146521 -
HLA-DQ:gluten tetramer test in blood gives better detection of coeliac patients than biopsy after 14-day gluten challenge
Gut, 67 (9), 1606-1613
DOI 10.1136/gutjnl-2017-314461, PubMed 28779027 -
Preclinical imaging methods for assessing the safety and efficacy of regenerative medicine therapies
NPJ Regen Med, 2, 28
DOI 10.1038/s41536-017-0029-9, PubMed 29302362 -
Human Adipose-Derived Mesenchymal Stem Cells Respond to Short-Term Hypoxia by Secreting Factors Beneficial for Human Islets In Vitro and Potentiate Antidiabetic Effect In Vivo
Cell Med, 9 (3), 103-116
DOI 10.3727/215517917X693401, PubMed 28713640 -
The alternative complement pathway is dysregulated in patients with chronic heart failure
Sci Rep, 7, 42532
DOI 10.1038/srep42532, PubMed 28195242 -
Plasma complement and vascular complement deposition in patients with coronary artery disease with and without inflammatory rheumatic diseases
PLoS One, 12 (3), e0174577
DOI 10.1371/journal.pone.0174577, PubMed 28362874 -
Development of an inducible platform for intercellular protein delivery
Int J Pharm, 522 (1-2), 1-10
DOI 10.1016/j.ijpharm.2017.02.067, PubMed 28254654 -
Future Challenges in the Generation of Hepatocyte-Like Cells From Human Pluripotent Stem Cells
Curr. Pathobiol. Rep., 5 (3), 301-314
DOI 10.1007/s40139-017-0150-x -
Fructan, Rather Than Gluten, Induces Symptoms in Patients With Self-Reported Non-Celiac Gluten Sensitivity
Gastroenterology, 154 (3), 529-539.e2
DOI 10.1053/j.gastro.2017.10.040, PubMed 29102613 -
Stereotyped antibody responses target posttranslationally modified gluten in celiac disease
JCI Insight, 2 (17)
DOI 10.1172/jci.insight.93961, PubMed 28878138 -
The roles of MHC class II genes and post-translational modification in celiac disease
Immunogenetics, 69 (8-9), 605-616
DOI 10.1007/s00251-017-0985-7, PubMed 28695286 -
Frontline Science: A hyporesponsive subset of rat NK cells negative for Ly49s3 and NKR-P1B are precursors to the functionally mature NKR-P1B+ subset
J Leukoc Biol, 102 (6), 1289-1298
DOI 10.1189/jlb.1HI0517-177RR, PubMed 28747319 -
Dyslipidemia in systemic lupus erythematosus
Immunol Res, 65 (2), 543-550
DOI 10.1007/s12026-016-8892-9, PubMed 28168401 -
The effect of medium composition on deposition of collagen type 1 and expression of osteogenic genes in mesenchymal stem cells derived from human adipose tissue and bone marrow
Process Biochem., 59, 321-328
DOI 10.1016/j.procbio.2016.10.011 -
Cytotoxic Effect on Human Myeloma Cells and Leukemic Cells by the Agaricus blazei Murill Based Mushroom Extract, Andosan™
Biomed Res Int, 2017, 2059825
DOI 10.1155/2017/2059825, PubMed 29238712 -
The nuclear receptor ERβ engages AGO2 in regulation of gene transcription, RNA splicing and RISC loading
Genome Biol, 18 (1), 189
DOI 10.1186/s13059-017-1321-0, PubMed 29017520 -
Interleukin-6 in Allogeneic Stem Cell Transplantation: Its Possible Importance for Immunoregulation and As a Therapeutic Target
Front Immunol, 8, 667
DOI 10.3389/fimmu.2017.00667, PubMed 28642760 -
Noninvasive Imaging of Human Immune Responses in a Human Xenograft Model of Graft-Versus-Host Disease
J Nucl Med, 58 (6), 1003-1008
DOI 10.2967/jnumed.116.186007, PubMed 28209904 -
Combining HIC, SEC, and IEX with Fluorescence Polarization for Drug Target Discovery
LC GC Eur., 30 (5), 232-239 -
Novel serum and bile protein markers predict primary sclerosing cholangitis disease severity and prognosis
J Hepatol, 66 (6), 1214-1222
DOI 10.1016/j.jhep.2017.01.019, PubMed 28161472 -
HLA class II alleles in Norwegian patients with coexisting type 1 diabetes and celiac disease
HLA, 89 (5), 278-284
DOI 10.1111/tan.12986, PubMed 28247576 -
Plasma immunological markers in pregnancy and cord blood: A possible link between macrophage chemo-attractants and risk of childhood type 1 diabetes
Am J Reprod Immunol, 79 (3)
DOI 10.1111/aji.12802, PubMed 29266506 -
Modeling and docking of antibody structures with Rosetta
Nat Protoc, 12 (2), 401-416
DOI 10.1038/nprot.2016.180, PubMed 28125104 -
Neonatal alloimmune thrombocytopaenia associated with maternal HLA antibodies
BMJ Case Rep, 2017
DOI 10.1136/bcr-2016-218269, PubMed 28679510 -
Bypassing adverse injection reactions to nanoparticles through shape modification and attachment to erythrocytes
Nat Nanotechnol, 12 (6), 589-594
DOI 10.1038/nnano.2017.47, PubMed 28396605 -
Iron oxide nanoparticles induce cytokine secretion in a complement-dependent manner in a human whole blood model
Int J Nanomedicine, 12, 3927-3940
DOI 10.2147/IJN.S136453, PubMed 28579778 -
Intracoronary autologous bone marrow cell transfer after myocardial infarction: the BOOST-2 randomised placebo-controlled clinical trial
Eur Heart J, 38 (39), 2936-2943
DOI 10.1093/eurheartj/ehx188, PubMed 28431003 -
Transforming growth factor beta (TGF-β) in adolescent chronic fatigue syndrome
J Transl Med, 15 (1), 245
DOI 10.1186/s12967-017-1350-1, PubMed 29202780 -
Hematopoietic stem cell transplantation in autoimmune disorders: From immune-regulatory processes to clinical implications
Autoimmun Rev, 16 (8), 817-825
DOI 10.1016/j.autrev.2017.05.020, PubMed 28572052 -
Rapid recovery and altered neurochemical dependence of locomotor central pattern generation following lumbar neonatal spinal cord injury
J Physiol, 596 (2), 281-303
DOI 10.1113/JP274484, PubMed 29086918
Publications 2016
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Differential Effects of Environmental and Genetic Factors on T and B Cell Immune Traits
Cell Rep, 17 (9), 2474-2487
DOI 10.1016/j.celrep.2016.10.053, PubMed 27818087 -
Coupling of HIV-1 Antigen to the Selective Autophagy Receptor SQSTM1/p62 Promotes T-Cell-Mediated Immunity
Front Immunol, 7, 167
DOI 10.3389/fimmu.2016.00167, PubMed 27242780 -
Broad and Largely Concordant Molecular Changes Characterize Tolerogenic and Immunogenic Dendritic Cell Maturation in Thymus and Periphery
Immunity, 45 (2), 305-18
DOI 10.1016/j.immuni.2016.07.019, PubMed 27533013 -
Increased Levels of Interferon-Inducible Protein 10 (IP-10) in 22q11.2 Deletion Syndrome
Scand J Immunol, 83 (3), 188-94
DOI 10.1111/sji.12406, PubMed 26708691 -
Complement activation is a crucial pathogenic factor in catastrophic antiphospholipid syndrome
Rheumatology (Oxford), 55 (7), 1337-9
DOI 10.1093/rheumatology/kew040, PubMed 27105662 -
Dual inhibition of complement and Toll-like receptors as a novel approach to treat inflammatory diseases-C3 or C5 emerge together with CD14 as promising targets
J Leukoc Biol, 101 (1), 193-204
DOI 10.1189/jlb.3VMR0316-132R, PubMed 27581539 -
Systemic therapy with oncolytic myxoma virus cures established residual multiple myeloma in mice
Mol Ther Oncolytics, 3, 16032
DOI 10.1038/mto.2016.32, PubMed 27933316 -
Differential propagation of stroma and cancer stem cells dictates tumorigenesis and multipotency
Oncogene, 36 (4), 570-584
DOI 10.1038/onc.2016.230, PubMed 27345406 -
Ultrasonic Surgical Aspirate is a Reliable Source For Culturing Glioblastoma Stem Cells
Sci Rep, 6, 32788
DOI 10.1038/srep32788, PubMed 27605047 -
Hampered Lung Maturation in Methimazole-Induced Hypothyroidism in Fetal Chicken: Morphological and Molecular Correlates to Human Fetal Development
Neonatology, 110 (2), 83-92
DOI 10.1159/000444656, PubMed 27070722 -
The Role of Animal Models in the Study of Hematopoietic Stem Cell Transplantation and GvHD: A Historical Overview
Front Immunol, 7, 333
DOI 10.3389/fimmu.2016.00333, PubMed 27625651 -
Antibody-antigen kinetics constrain intracellular humoral immunity
Sci Rep, 6, 37457
DOI 10.1038/srep37457, PubMed 27881870 -
A Longitudinal Follow-up of Autoimmune Polyendocrine Syndrome Type 1
J Clin Endocrinol Metab, 101 (8), 2975-83
DOI 10.1210/jc.2016-1821, PubMed 27253668 -
Dissecting the interaction between transglutaminase 2 and fibronectin
Amino Acids, 49 (3), 489-500
DOI 10.1007/s00726-016-2296-y, PubMed 27394141 -
The role of microRNAs in the pathogenesis of autoimmune diseases
Autoimmun Rev, 15 (12), 1171-1180
DOI 10.1016/j.autrev.2016.09.003, PubMed 27639156 -
Toll-Like Receptor Pathways in Autoimmune Diseases
Clin Rev Allergy Immunol, 50 (1), 1-17
DOI 10.1007/s12016-015-8473-z, PubMed 25687121 -
Data on circulating leukocyte subpopulations and inflammatory proteins in children with familial hypercholesterolemia and healthy children
Data Brief, 10, 587-592
DOI 10.1016/j.dib.2016.12.042, PubMed 28070551 -
Altered leukocyte distribution under hypercholesterolemia: A cross-sectional study in children with familial hypercholesterolemia
Atherosclerosis, 256, 67-74
DOI 10.1016/j.atherosclerosis.2016.11.031, PubMed 28024183 -
Healthy HLA-DQ2.5+ Subjects Lack Regulatory and Memory T Cells Specific for Immunodominant Gluten Epitopes of Celiac Disease
J Immunol, 196 (6), 2819-26
DOI 10.4049/jimmunol.1501152, PubMed 26895834 -
3D bioprinting of BM-MSCs-loaded ECM biomimetic hydrogels for in vitro neocartilage formation
Biofabrication, 8 (3), 035002
DOI 10.1088/1758-5090/8/3/035002, PubMed 27431574 -
TCR sequencing of single cells reactive to DQ2.5-glia-α2 and DQ2.5-glia-ω2 reveals clonal expansion and epitope-specific V-gene usage
Mucosal Immunol, 9 (3), 587-96
DOI 10.1038/mi.2015.147, PubMed 26838051 -
Expanding the tools for identifying mononuclear phagocyte subsets in swine: Reagents to porcine CD11c and XCR1
Dev Comp Immunol, 65, 31-40
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