Michal Kostas

  • Researcher; PhD
 

Publications 2021

Szybowska P, Kostas M, Wesche J, Haugsten EM, Wiedlocha A (2021)
Negative Regulation of FGFR (Fibroblast Growth Factor Receptor) Signaling
Cells, 10 (6), 1342
DOI 10.3390/cells10061342

Vikan AK, Kostas M, Haugsten EM, Selbo PK, Wesche J (2021)
Efficacy and Selectivity of FGF2-Saporin Cytosolically Delivered by PCI in Cells Overexpressing FGFR1
Cells, 10 (6), 1476
DOI 10.3390/cells10061476

Publications 2019

Szybowska P, Kostas M, Wesche J, Wiedlocha A, Haugsten EM (2019)
Cancer Mutations in FGFR2 Prevent a Negative Feedback Loop Mediated by the ERK1/2 Pathway
Cells, 8 (6)
DOI 10.3390/cells8060518

Publications 2018

Fafilek B, Balek L, Bosakova MK, Varecha M, Nita A, Gregor T, Gudernova I, Krenova J, Ghosh S, Piskacek M, Jonatova L, Cernohorsky NH, Zieba JT, Kostas M, Haugsten EM, Wesche J, Erneux C, Trantirek L, Krakow D, Krejci P (2018)
The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases
Sci. Signal., 11 (548), eaap8608
DOI 10.1126/scisignal.aap8608

Kostas M, Haugsten EM, Zhen Y, Sorensen V, Szybowska P, Fiorito E, Lorenz S, Jones N, de Souza GA, Wiedlocha A, Wesche J (2018)
Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Controls Fibroblast Growth Factor Receptor (FGFR) 1 Activity and Influences Sensitivity to FGFR Kinase Inhibitors
Mol. Cell. Proteomics, 17 (5), 850-870
DOI 10.1074/mcp.RA117.000538

Publications 2016

Bober J, Olsnes S, Kostas M, Bogacz M, Zakrzewska M, Otlewski J (2016)
Identification of New FGF1 Binding Partners-Implications for Its Intracellular Function
IUBMB Life, 68 (3), 242-251
DOI 10.1002/iub.1480

Publications 2015

Buchtova M, Chaloupkova R, Zakrzewska M, Vesela I, Cela P, Barathova J, Gudernova I, Zajickova R, Trantirek L, Martin J, Kostas M, Otlewski J, Damborsky J, Kozubik A, Wiedlocha A, Krejci P (2015)
Instability restricts signaling of multiple fibroblast growth factors
Cell. Mol. Life Sci., 72 (12), 2445-2459
DOI 10.1007/s00018-015-1856-8

Publications 2014

Sletten T, Kostas M, Bober J, Sorensen V, Yadollahi M, Olsnes S, Tomala J, Otlewski J, Zakrzewska M, Wiedlocha A (2014)
Nucleolin Regulates Phosphorylation and Nuclear Export of Fibroblast Growth Factor 1 (FGF1)
PLoS One, 9 (3), e90687
DOI 10.1371/journal.pone.0090687