Therapeutic drug monitoring of TNFinhibitors and other therapeutic antibodies.
Develop assays for novel immunotherapy drugs such as pembrolizumab, nivolumab and ipilimumab for monitoring drug levels in patients with lung cancer and malignant melanoma.
Develop assays for measuring rituximab and anti-rituximab for monitoring drug level and anti-drug antibody formation.
Detection of antibodies to transglutaminase in the HUNT4-cohort using an in-house dual label assay in collaborative study “Coeliac disease in HUNT”.
Screening for patient antibodies to HH1, a novel antibody-based drug used in lymphoma clinical trials (Lymrit).
Fosså SD, Bjerner LJ, Tandstad T, Brydøy M, Dahl AA, Nome RV, Negaard H, Myklebust TÅ, Haugnes HS(2025) Biochemical Hypogonadism in Aging Testicular Cancer Survivors: A Clinical Challenge Eur Urol Open Sci, 72, 10-16 DOI 10.1016/j.euros.2024.12.010, PubMed 39897186
Lundekvam JA, Høivik ML, Anisdahl K, Småstuen MC, Warren DJ, Bolstad N, Medhus AW(2025) Tumour necrosis factor inhibitors in Ulcerative colitis: real-world data on Therapeutic drug monitoring and evaluation of current treatment targets (STRIDE II) Ann Med, 57(1), 2424447 DOI 10.1080/07853890.2024.2424447, PubMed 39757985
Nome RV, Flatebø Ø, Bøe SL, Klaasen RA, Aamdal E, Normann M, Bolstad N, Warren DJ(2024) A simple automated assay format for measuring multiple immune checkpoint inhibitors J Pharm Biomed Anal, 255, 116657 DOI 10.1016/j.jpba.2024.116657, PubMed 39756153
