Biochemical endocrinology and metabolism research group Publications

Publications 2019

Bornstedt ME, Gjerlaugsen N, Pepaj M, Bredahl MKL, Thorsby PM (2019)
Vitamin D Increases Glucose Stimulated Insulin Secretion from Insulin Producing Beta Cells (INS1E)
Int J Endocrinol Metab, 17 (1), e74255
DOI 10.5812/ijem.74255, PubMed 30881469

Gustafsson MK, Romundstad PR, Stafne SN, Helvik AS, Stunes AK, Mørkved S, Salvesen KÅ, Thorsby PM, Mosti MP, Syversen U (2019)
The effect of an exercise program in pregnancy on vitamin D status among healthy, pregnant Norwegian women: a randomized controlled trial
BMC Pregnancy Childbirth, 19 (1), 76
DOI 10.1186/s12884-019-2220-z, PubMed 30786861

Jorde R, Stunes AK, Kubiak J, Joakimsen R, Grimnes G, Thorsby PM, Syversen U (2019)
Effects of vitamin D supplementation on bone turnover markers and other bone-related substances in subjects with vitamin D deficiency
Bone, 124, 7-13 (in press)
DOI 10.1016/j.bone.2019.04.002, PubMed 30959189

Juvodden HT, Alnæs D, Lund MJ, Dietrichs E, Thorsby PM, Westlye LT, Knudsen S (2019)
Hypocretin-deficient narcolepsy patients have abnormal brain activation during humor processing
Sleep (in press)
DOI 10.1093/sleep/zsz082, PubMed 30923809

Næss-Andresen ML, Eggemoen ÅR, Berg JP, Falk RS, Jenum AK (2019)
Serum ferritin, soluble transferrin receptor, and total body iron for the detection of iron deficiency in early pregnancy: a multiethnic population-based study with low use of iron supplements
Am J Clin Nutr, 109 (3), 566-575
DOI 10.1093/ajcn/nqy366, PubMed 30831600

Tapia G, Mårild K, Dahl SR, Lund-Blix NA, Viken MK, Lie BA, Njølstad PR, Joner G, Skrivarhaug T, Cohen AS, Størdal K, Stene LC (2019)
Maternal and Newborn Vitamin D-Binding Protein, Vitamin D Levels, Vitamin D Receptor Genotype, and Childhood Type 1 Diabetes
Diabetes Care, 42 (4), 553-559
DOI 10.2337/dc18-2176, PubMed 30692241

Publications 2018

Berg AO, Jørgensen KN, Nerhus M, Athanasiu L, Popejoy AB, Bettella F, Norbom LCB, Gurholt TP, Dahl SR, Andreassen OA, Djurovic S, Agartz I, Melle I (2018)
Vitamin D levels, brain volume, and genetic architecture in patients with psychosis
PLoS One, 13 (8), e0200250
DOI 10.1371/journal.pone.0200250, PubMed 30142216

Dahl SR, Nermoen I, Brøndstad I, Husebye ES, Løvås K, Thorsby PM (2018)
Assay of steroids by liquid chromatography-tandem mass spectrometry in monitoring 21-hydroxylase deficiency
Endocr Connect, 7 (12), 1542-1550
DOI 10.1530/EC-18-0453, PubMed 30530876

Gopinathan U, Redalen KR, Trøseid AM, Kierulf P, Brandtzaeg P, Ree AH, Berg JP, Øvstebø R (2018)
Large-scale reduction of tyrosine kinase activities in human monocytes stimulated in vitro with N. meningitidis
PLoS One, 13 (1), e0181912
DOI 10.1371/journal.pone.0181912, PubMed 29357362

Gustafsson MK, Romundstad PR, Stafne SN, Helvik AS, Stunes AK, Mørkved S, Salvesen KÅ, Thorsby PM, Syversen U (2018)
Alterations in the vitamin D endocrine system during pregnancy: A longitudinal study of 855 healthy Norwegian women
PLoS One, 13 (4), e0195041
DOI 10.1371/journal.pone.0195041, PubMed 29641551

Hassel B, Mariussen E, Idland AV, Dahl GT, Ræder J, Frihagen F, Berg JP, Chaudhry FA, Wyller TB, Watne LO (2018)
CSF sodium at toxic levels precedes delirium in hip fracture patients
Neurotoxicology, 69, 11-16
DOI 10.1016/j.neuro.2018.08.010, PubMed 30149051

Juvodden HT, Alnæs D, Lund MJ, Agartz I, Andreassen OA, Dietrichs E, Thorsby PM, Westlye LT, Knudsen S (2018)
Widespread white matter changes in post-H1N1 patients with narcolepsy type 1 and first-degree relatives
Sleep, 41 (10)
DOI 10.1093/sleep/zsy145, PubMed 30016530

Kubiak J, Thorsby PM, Kamycheva E, Jorde R (2018)
Vitamin D supplementation does not improve CVD risk factors in vitamin D-insufficient subjects
Endocr Connect, 7 (6), 840-849
DOI 10.1530/EC-18-0144, PubMed 29764903

Pasovic L, Utheim TP, Reppe S, Khan AZ, Jackson CJ, Thiede B, Berg JP, Messelt EB, Eidet JR (2018)
Improvement of Storage Medium for Cultured Human Retinal Pigment Epithelial Cells Using Factorial Design
Sci Rep, 8 (1), 5688
DOI 10.1038/s41598-018-24121-8, PubMed 29632395

Schwettmann L, Berg JP, Sandberg S (2018)
HbA1c skal angis i mmol/mol
Tidsskr Nor Laegeforen, 138 (15)
DOI 10.4045/tidsskr.18.0633, PubMed 30277042

Schwettmann L, Berg JP, Sandberg S (2018)
HbA1c must be indicated in mmol/mol
Tidsskr. Nor. Laegeforen., 138 (15), 1404-1405

Sørgjerd EP, Åsvold BO, Thorsby PM, Grill V (2018)
Individuals Fulfilling Criteria for Type 2 Diabetes Rather Than LADA Display Transient Signs of Autoimmunity Preceding Diagnosis With Possible Clinical Implications: The HUNT Study
Diabetes Care, 41 (12), e161-e163
DOI 10.2337/dc18-1069, PubMed 30327361

Ueland GÅ, Methlie P, Øksnes M, Thordarson HB, Sagen J, Kellmann R, Mellgren G, Ræder M, Dahlqvist P, Dahl SR, Thorsby PM, Løvås K, Husebye ES (2018)
The Short Cosyntropin Test Revisited: New Normal Reference Range Using LC-MS/MS
J Clin Endocrinol Metab, 103 (4), 1696-1703
DOI 10.1210/jc.2017-02602, PubMed 29452421

Øystese KAB, Berg JP, Normann KR, Zucknick M, Casar-Borota O, Bollerslev J (2018)
The role of E and N-cadherin in the postoperative course of gonadotroph pituitary tumours
Endocrine, 62 (2), 351-360
DOI 10.1007/s12020-018-1679-0, PubMed 30051197

Aass HCD, Hellum M, Trøseid AS, Brandtzaeg P, Berg JP, Øvstebø R, Henriksson CE (2018)
Whole-blood incubation with the Neisseria meningitidis lpxL1 mutant induces less pro-inflammatory cytokines than the wild type, and IL-10 reduces the MyD88-dependent cytokines
Innate Immun, 24 (2), 101-111
DOI 10.1177/1753425917749299, PubMed 29313733

Publications 2017

Berents TL, Carlsen KCL, Mowinckel P, Skjerven HO, Rolfsjord LB, Nordhagen LS, Kvenshagen B, Hunderi JOG, Bradley M, Thorsby PM, Carlsen KH, Gjersvik P (2017)
Weight-for-length, early weight-gain velocity and atopic dermatitis in infancy and at two years of age: a cohort study
BMC Pediatr, 17 (1), 141
DOI 10.1186/s12887-017-0889-6, PubMed 28592289

Brusletto BS, Hellerud BC, Løberg EM, Goverud IL, Vege Å, Berg JP, Brandtzaeg P, Øvstebø R (2017)
Traceability and distribution of Neisseria meningitidis DNA in archived post mortem tissue samples from patients with systemic meningococcal disease
BMC Clin Pathol, 17, 10
DOI 10.1186/s12907-017-0049-9, PubMed 28824331

Gopinathan U, Øvstebø R, Brusletto BS, Olstad OK, Kierulf P, Brandtzaeg P, Berg JP (2017)
Transcriptomic data from two primary cell models stimulating human monocytes suggest inhibition of oxidative phosphorylation and mitochondrial function by N. meningitidis which is partially up-regulated by IL-10
BMC Immunol, 18 (1), 46
DOI 10.1186/s12865-017-0229-5, PubMed 29078758

Klingenberg O, Furuset T, Hestbråten CR, Hallberg MH, Steiro A, Orset IR, Berg JP (2017)
HbA1c analysis by capillary electrophoresis - comparison with chromatography and an immunological method
Scand J Clin Lab Invest, 77 (6), 458-464
DOI 10.1080/00365513.2017.1338747, PubMed 28644050

Krog AH, Thorsby PM, Sahba M, Pettersen EM, Sandven I, Jørgensen JJ, Sundhagen JO, Kazmi SS (2017)
Perioperative humoral stress response to laparoscopic versus open aortobifemoral bypass surgery
Scand J Clin Lab Invest, 77 (2), 83-92
DOI 10.1080/00365513.2016.1268264, PubMed 28067075

Mårild K, Tapia G, Haugen M, Dahl SR, Cohen AS, Lundqvist M, Lie BA, Stene LC, Størdal K (2017)
Maternal and neonatal vitamin D status, genotype and childhood celiac disease
PLoS One, 12 (7), e0179080
DOI 10.1371/journal.pone.0179080, PubMed 28686601

Nerhus M, Berg AO, Simonsen C, Haram M, Haatveit B, Dahl SR, Gurholt TP, Bjella TD, Ueland T, Andreassen OA, Melle I (2017)
Vitamin D Deficiency Associated With Cognitive Functioning in Psychotic Disorders
J Clin Psychiatry, 78 (7), e750-e757
DOI 10.4088/JCP.16m10880, PubMed 28493652

Risstad H, Kristinsson JA, Fagerland MW, le Roux CW, Birkeland KI, Gulseth HL, Thorsby PM, Vincent RP, Engström M, Olbers T, Mala T (2017)
Bile acid profiles over 5 years after gastric bypass and duodenal switch: results from a randomized clinical trial
Surg Obes Relat Dis, 13 (9), 1544-1553
DOI 10.1016/j.soard.2017.05.024, PubMed 28756050

Sørensen IM, Joner G, Jenum PA, Eskild A, Dahl SR, Stene LC (2017)
Maternal serum calcitriol during pregnancy and risk of childhood onset type 1 diabetes
Acta Diabetol, 54 (12), 1143-1145
DOI 10.1007/s00592-017-1045-3, PubMed 28875306

Viste R, Soosai J, Vikin T, Thorsby PM, Nilsen KB, Knudsen S (2017)
Long-term improvement after combined immunomodulation in early post-H1N1 vaccination narcolepsy
Neurol Neuroimmunol Neuroinflamm, 4 (5), e389
DOI 10.1212/NXI.0000000000000389, PubMed 28840177

Vistnes M, Tapia G, Mårild K, Midttun Ø, Ueland PM, Viken MK, Magnus P, Berg JP, Gillespie KM, Skrivarhaug T, Njølstad PR, Joner G, Størdal K, Stene LC (2017)
Plasma immunological markers in pregnancy and cord blood: A possible link between macrophage chemo-attractants and risk of childhood type 1 diabetes
Am J Reprod Immunol, 79 (3)
DOI 10.1111/aji.12802, PubMed 29266506

Øystese KA, Casar-Borota O, Normann KR, Zucknick M, Berg JP, Bollerslev J (2017)
Estrogen Receptor α, a Sex-Dependent Predictor of Aggressiveness in Nonfunctioning Pituitary Adenomas: SSTR and Sex Hormone Receptor Distribution in NFPA
J Clin Endocrinol Metab, 102 (9), 3581-3590
DOI 10.1210/jc.2017-00792, PubMed 28911153

Aass C, Norheim I, Eriksen EF, Børnick EC, Thorsby PM, Pepaj M (2017)
Establishment of a tear protein biomarker panel differentiating between Graves' disease with or without orbitopathy
PLoS One, 12 (4), e0175274
DOI 10.1371/journal.pone.0175274, PubMed 28419103

Publications 2016

Beitland S, Waldum-Grevbo BE, Nakstad ER, Berg JP, Trøseid AS, Brusletto BS, Brunborg C, Andersen GØ, Sunde K (2016)
Urine biomarkers give early prediction of acute kidney injury and outcome after out-of-hospital cardiac arrest
Crit Care, 20 (1), 314
DOI 10.1186/s13054-016-1503-2, PubMed 27716377

Berents TL, Lødrup Carlsen KC, Mowinckel P, Sandvik L, Skjerven HO, Rolfsjord LB, Kvenshagen B, Hunderi JO, Bradley M, Lieden A, Carlsen KH, Thorsby PM, Gjersvik P (2016)
Vitamin D levels and atopic eczema in infancy and early childhood in Norway: a cohort study
Br J Dermatol, 175 (1), 95-101
DOI 10.1111/bjd.14537, PubMed 26972308

Frigstad SO, Høivik M, Jahnsen J, Dahl SR, Cvancarova M, Grimstad T, Berset IP, Huppertz-Hauss G, Hovde Ø, Torp R, Bernklev T, Moum B, Jelsness-Jørgensen LP (2016)
Vitamin D deficiency in inflammatory bowel disease: prevalence and predictors in a Norwegian outpatient population
Scand J Gastroenterol, 52 (1), 100-106
DOI 10.1080/00365521.2016.1233577, PubMed 27603182

Hellum M, Trøseid AS, Berg JP, Brandtzaeg P, Øvstebø R, Henriksson CE (2016)
The Neisseria meningitidis lpxL1 mutant induces less tissue factor expression and activity in primary human monocytes and monocyte-derived microvesicles than the wild type meningococcus
Innate Immun, 23 (2), 196-205
DOI 10.1177/1753425916684201, PubMed 28024455

Hov KR, Berg JP, Frihagen F, Ræder J, Hall R, Wyller TB, Watne LO (2016)
Blood-Cerebrospinal Fluid Barrier Integrity in Delirium Determined by Q-Albumin
Dement Geriatr Cogn Disord, 41 (3-4), 192-8
DOI 10.1159/000443789, PubMed 27058253

Jørgenrud B, Stene LC, Tapia G, Bøås H, Pepaj M, Berg JP, Thorsby PM, Orešič M, Hyötyläinen T, Rønningen KS (2016)
Longitudinal plasma metabolic profiles, infant feeding, and islet autoimmunity in the MIDIA study
Pediatr Diabetes, 18 (2), 111-119
DOI 10.1111/pedi.12360, PubMed 26791677

Kristensen GB, Rustad P, Berg JP, Aakre KM (2016)
Analytical Bias Exceeding Desirable Quality Goal in 4 out of 5 Common Immunoassays: Results of a Native Single Serum Sample External Quality Assessment Program for Cobalamin, Folate, Ferritin, Thyroid-Stimulating Hormone, and Free T4 Analyses
Clin Chem, 62 (9), 1255-63
DOI 10.1373/clinchem.2016.258962, PubMed 27384539

Krog AH, Sahba M, Pettersen EM, Sandven I, Thorsby PM, Jørgensen JJ, Sundhagen JO, Kazmi SS (2016)
Comparison of the acute-phase response after laparoscopic versus open aortobifemoral bypass surgery: a substudy of a randomized controlled trial
Vasc Health Risk Manag, 12, 371-378
DOI 10.2147/VHRM.S110600, PubMed 27713633

Methi T, Thorsby PM (2016)
Insulin resistance - the body's defence against caloric intoxication?
Tidsskr Nor Laegeforen, 136 (11), 1015-7
DOI 10.4045/tidsskr.16.0259, PubMed 27325036

Methi T, Thorsby PM (2016)
[Not Available]
Tidsskr Nor Laegeforen, 136 (14-15), 1186
DOI 10.4045/tidsskr.16.0582, PubMed 27554546

Mårild K, Vistnes M, Tapia G, Midttun Ø, Ueland PM, Viken MK, Magnus P, Berg JP, Stene LC, Størdal K (2016)
Midpregnancy and cord blood immunologic biomarkers, HLA genotype, and pediatric celiac disease
J Allergy Clin Immunol, 139 (5), 1696-1698
DOI 10.1016/j.jaci.2016.10.016, PubMed 27865861

Nerhus M, Berg AO, Kvitland LR, Dieset I, Hope S, Dahl SR, Weibell MA, Romm KL, Faerden A, Andreassen OA, Melle I (2016)
Low vitamin D is associated with negative and depressive symptoms in psychotic disorders
Schizophr Res, 178 (1-3), 44-49
DOI 10.1016/j.schres.2016.08.024, PubMed 27595553

Normann KR, Øystese KAB, Berg JP, Lekva T, Berg-Johnsen J, Bollerslev J, Olarescu NC (2016)
Selection and validation of reliable reference genes for RT-qPCR analysis in a large cohort of pituitary adenomas
Mol Cell Endocrinol, 437, 183-189
DOI 10.1016/j.mce.2016.08.030, PubMed 27561203

Olsen HG, Knutsen TM, Lewandowska-Sabat AM, Grove H, Nome T, Svendsen M, Arnyasi M, Sodeland M, Sundsaasen KK, Dahl SR, Heringstad B, Hansen HH, Olsaker I, Kent MP, Lien S (2016)
Fine mapping of a QTL on bovine chromosome 6 using imputed full sequence data suggests a key role for the group-specific component (GC) gene in clinical mastitis and milk production
Genet Sel Evol, 48 (1), 79
DOI 10.1186/s12711-016-0257-2, PubMed 27760518

Pepaj M, Bredahl MK, Gjerlaugsen N, Thorsby PM (2016)
Proteomic analysis of the INS-1E secretome identify novel vitamin D-regulated proteins
Diabetes Metab Res Rev, 32 (6), 514-21
DOI 10.1002/dmrr.2777, PubMed 26788927

Sachse D, Solevåg AL, Berg JP, Nakstad B (2016)
The Role of Plasma and Urine Metabolomics in Identifying New Biomarkers in Severe Newborn Asphyxia: A Study of Asphyxiated Newborn Pigs following Cardiopulmonary Resuscitation
PLoS One, 11 (8), e0161123
DOI 10.1371/journal.pone.0161123, PubMed 27529347

Sollid ST, Hutchinson MY, Berg V, Fuskevåg OM, Figenschau Y, Thorsby PM, Jorde R (2016)
Effects of vitamin D binding protein phenotypes and vitamin D supplementation on serum total 25(OH)D and directly measured free 25(OH)D
Eur J Endocrinol, 174 (4), 445-52
DOI 10.1530/EJE-15-1089, PubMed 26733479

Sommer C, Gulseth HL, Jenum AK, Sletner L, Thorsby PM, Birkeland KI (2016)
Soluble Leptin Receptor and Risk of Gestational Diabetes in a Multiethnic Population: A Prospective Cohort Study
J Clin Endocrinol Metab, 101 (11), 4070-4075
DOI 10.1210/jc.2016-2583, PubMed 27537771

Waage C, Jenum AK, Mdala I, Berg JP, Richardsen K, Birkeland K (2016)
Associations between gestational diabetes mellitus and elevated HbA1c early postpartum in a multi-ethnic population
Prim Care Diabetes, 11 (2), 132-139
DOI 10.1016/j.pcd.2016.09.007, PubMed 27771271

Aass C, Norheim I, Eriksen EF, Børnick EC, Thorsby PM, Pepaj M (2016)
Comparative proteomic analysis of tear fluid in Graves' disease with and without orbitopathy
Clin Endocrinol (Oxf), 85 (5), 805-812
DOI 10.1111/cen.13122, PubMed 27256639

Publications 2015

Kringen MK, Stormo C, Berg JP, Terry SF, Vocke CM, Rizvi S, Hendig D, Piehler AP (2015)
Copy number variation in the ATP-binding cassette transporter ABCC6 gene and ABCC6 pseudogenes in patients with pseudoxanthoma elasticum
Mol Genet Genomic Med, 3 (3), 233-7
DOI 10.1002/mgg3.137, PubMed 26029710

Lekva T, Berg JP, Lyle R, Heck A, Bollerslev J, Ueland T (2015)
Alternative splicing of placental lactogen (CSH2) in somatotroph pituitary adenomas
Neuro Endocrinol Lett, 36 (2), 136-42
PubMed 26071582

Nerhus M, Berg AO, Dahl SR, Holvik K, Gardsjord ES, Weibell MA, Bjella TD, Andreassen OA, Melle I (2015)
Vitamin D status in psychotic disorder patients and healthy controls--The influence of ethnic background
Psychiatry Res, 230 (2), 616-21
DOI 10.1016/j.psychres.2015.10.015, PubMed 26500071

Pepaj M, Bredahl MK, Gjerlaugsen N, Bornstedt ME, Thorsby PM (2015)
Discovery of novel vitamin D-regulated proteins in INS-1 cells: a proteomic approach
Diabetes Metab Res Rev, 31 (5), 481-91
DOI 10.1002/dmrr.2629, PubMed 25449168

Pepaj M, Thorsby PM (2015)
Analysis of Glycated Albumin by On-Line Two-Dimensional Liquid Chromatography Mass Spectrometry
J. Liq. Chromatogr. Relat. Technol., 38 (1), 20-28

Reppe S, Noer A, Grimholt RM, Halldórsson BV, Medina-Gomez C, Gautvik VT, Olstad OK, Berg JP, Datta H, Estrada K, Hofman A, Uitterlinden AG, Rivadeneira F, Lyle R, Collas P, Gautvik KM (2015)
Methylation of bone SOST, its mRNA, and serum sclerostin levels correlate strongly with fracture risk in postmenopausal women
J Bone Miner Res, 30 (2), 249-56
DOI 10.1002/jbmr.2342, PubMed 25155887

Rizvi SM, Veierød MB, Thorsby PM, Helsing P (2015)
Vitamin D in Norwegian renal transplant recipients: A longitudinal study with repeated measurements in winter and summer
Eur J Dermatol, 25 (3), 234-9
DOI 10.1684/ejd.2015.2524, PubMed 26412038

Sørgjerd EP, Thorsby PM, Torjesen PA, Skorpen F, Kvaløy K, Grill V (2015)
Presence of anti-GAD in a non-diabetic population of adults; time dynamics and clinical influence: results from the HUNT study
BMJ Open Diabetes Res Care, 3 (1), e000076
DOI 10.1136/bmjdrc-2014-000076, PubMed 26157582

Aass C, Norheim I, Eriksen EF, Thorsby PM, Pepaj M (2015)
Single unit filter-aided method for fast proteomic analysis of tear fluid
Anal Biochem, 480, 1-5
DOI 10.1016/j.ab.2015.04.002, PubMed 25862084

 
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