Kristin Austlid Taskén
- Project group leader, Professor Institute for Cancer Research; PhD
- +47 22 78 18 78
Publications 2024
Systemic interrogation of immune-oncology-related proteins in patients with locally advanced prostate cancer undergoing androgen deprivation and intensity-modulated radiotherapy
World J Urol, 42 (1), 95
DOI 10.1007/s00345-024-04787-8, PubMed 38386171
Publications 2022
Low Blood Levels of LRG1 Before Radical Prostatectomy Identify Patients with High Risk of Progression to Castration-resistant Prostate Cancer
Eur Urol Open Sci, 45, 68-75
DOI 10.1016/j.euros.2022.09.002, PubMed 36353660
Correlation of expression of Major Vault Protein with androgen receptor and immune checkpoint protein B7-H3, and with poor prognosis in prostate cancer
Pathol Res Pract, 241, 154243
DOI 10.1016/j.prp.2022.154243, PubMed 36481650
The Movember Global Action Plan 1 (GAP1): Unique Prostate Cancer Tissue Microarray Resource
Cancer Epidemiol Biomarkers Prev, 31 (4), 715-727
DOI 10.1158/1055-9965.EPI-21-0600, PubMed 35131885
Association of β-Blocker Use at Time of Radical Prostatectomy With Rate of Treatment for Prostate Cancer Recurrence
JAMA Netw Open, 5 (1), e2145230
DOI 10.1001/jamanetworkopen.2021.45230, PubMed 35080602
Publications 2021
Implication of β2-adrenergic receptor and miR-196a correlation in neurite outgrowth of LNCaP prostate cancer cells
PLoS One, 16 (6), e0253828
DOI 10.1371/journal.pone.0253828, PubMed 34191854
Integrating Serum Biomarkers into Prediction Models for Biochemical Recurrence Following Radical Prostatectomy
Cancers (Basel), 13 (16)
DOI 10.3390/cancers13164162, PubMed 34439316
Proteomic analyses identify major vault protein as a prognostic biomarker for fatal prostate cancer
Carcinogenesis, 42 (5), 685-693
DOI 10.1093/carcin/bgab015, PubMed 33609362
Extracellular vesicles as a source of prostate cancer biomarkers in liquid biopsies: a decade of research
Br J Cancer, 126 (3), 331-350
DOI 10.1038/s41416-021-01610-8, PubMed 34811504
Publications 2020
Identification and Validation of Leucine-rich α-2-glycoprotein 1 as a Noninvasive Biomarker for Improved Precision in Prostate Cancer Risk Stratification
Eur Urol Open Sci, 21, 51-60
DOI 10.1016/j.euros.2020.08.007, PubMed 34337468
Publications 2019
The β2-Adrenergic Receptor Is a Molecular Switch for Neuroendocrine Transdifferentiation of Prostate Cancer Cells
Mol Cancer Res, 17 (11), 2154-2168
DOI 10.1158/1541-7786.MCR-18-0605, PubMed 31395667
Serum levels of inflammation-related markers and metabolites predict response to neoadjuvant chemotherapy with and without bevacizumab in breast cancers
Int J Cancer, 146 (1), 223-235
DOI 10.1002/ijc.32638, PubMed 31444972
Prognostic biomarkers for immunotherapy with ipilimumab in metastatic melanoma
Clin Exp Immunol, 197 (1), 74-82
DOI 10.1111/cei.13283, PubMed 30821848
Low Expression of miR-424-3p is Highly Correlated with Clinical Failure in Prostate Cancer
Sci Rep, 9 (1), 10662
DOI 10.1038/s41598-019-47234-0, PubMed 31337863
Publications 2018
Levels and prognostic impact of circulating markers of inflammation, endothelial activation and extracellular matrix remodelling in patients with lung cancer and chronic obstructive pulmonary disease
BMC Cancer, 18 (1), 739
DOI 10.1186/s12885-018-4659-0, PubMed 30005623
Ex vivo metabolic fingerprinting identifies biomarkers predictive of prostate cancer recurrence following radical prostatectomy
Br J Cancer, 118 (6), e11
DOI 10.1038/bjc.2017.470, PubMed 29462127
Role of serum response factor expression in prostate cancer biochemical recurrence
Prostate, 78 (10), 724-730
DOI 10.1002/pros.23516, PubMed 29608018
Publications 2017
Ex vivo metabolic fingerprinting identifies biomarkers predictive of prostate cancer recurrence following radical prostatectomy
Br J Cancer, 117 (11), 1656-1664
DOI 10.1038/bjc.2017.346, PubMed 28972967
Publications 2016
Low β₂-adrenergic receptor level may promote development of castration resistant prostate cancer and altered steroid metabolism
Oncotarget, 7 (2), 1878-94
DOI 10.18632/oncotarget.6479, PubMed 26646591
Observed correlation between the expression levels of catalytic subunit, Cβ2, of cyclic adenosine monophosphate-dependent protein kinase and prostate cancer aggressiveness
Urol Oncol, 35 (3), 111.e1-111.e8
DOI 10.1016/j.urolonc.2016.10.002, PubMed 27838142
Tomato-based randomized controlled trial in prostate cancer patients: Effect on PSA
Clin Nutr, 36 (3), 672-679
DOI 10.1016/j.clnu.2016.06.014, PubMed 27406859
PBX3 is a putative biomarker of aggressive prostate cancer
Int J Cancer, 139 (8), 1810-20
DOI 10.1002/ijc.30220, PubMed 27273830
Publications 2015
β-Adrenergic Receptor Signaling in Prostate Cancer
Front Oncol, 4, 375
DOI 10.3389/fonc.2014.00375, PubMed 25629002
Publications 2013
TWIST1, A novel androgen-regulated gene, is a target for NKX3-1 in prostate cancer cells
Cancer Cell Int, 13 (1), 4
DOI 10.1186/1475-2867-13-4, PubMed 23368843
Association between use of β-blockers and prostate cancer-specific survival: a cohort study of 3561 prostate cancer patients with high-risk or metastatic disease
Eur Urol, 65 (3), 635-41
DOI 10.1016/j.eururo.2013.01.007, PubMed 23351721
Reply to Chris R. Cardwell, Samy Suissa and Liam J. Murray's letter to the editor re: Helene Hartvedt Grytli, Morten Wang Fagerland, Sophie D. Fosså, Kristin Austlid Taskén. Association between use of β-blockers and prostate cancer-specific survival: a cohort study of 3561 prostate cancer patients with high-risk or metastatic disease. Eur Urol. In press. http://dx.doi.org/10.1016/j.eururo.2013.01.007
Eur Urol, 64 (1), e11-2
DOI 10.1016/j.eururo.2013.03.045, PubMed 23602404
Publications 2012
Use of β-blockers is associated with prostate cancer-specific survival in prostate cancer patients on androgen deprivation therapy
Prostate, 73 (3), 250-60
DOI 10.1002/pros.22564, PubMed 22821802
The effects of short-term genistein intervention on prostate biomarker expression in patients with localised prostate cancer before radical prostatectomy
Br J Nutr, 108 (12), 2138-47
DOI 10.1017/S0007114512000384, PubMed 22397815
Publications 2011
Efficacy and safety of short-term genistein intervention in patients with localized prostate cancer prior to radical prostatectomy: a randomized, placebo-controlled, double-blind Phase 2 clinical trial
Nutr Cancer, 63 (6), 889-98
DOI 10.1080/01635581.2011.582221, PubMed 21714686
Regulation of PBX3 expression by androgen and Let-7d in prostate cancer
Mol Cancer, 10, 50
DOI 10.1186/1476-4598-10-50, PubMed 21548940
Publications 2010
The star chart to Ta bladder cancer: an unsophisticated analysis of two-dimensional gel electrophoresis proteome maps
Scand J Urol Nephrol, 44 (2), 76-83
DOI 10.3109/00365590903510729, PubMed 20059407
Publications 2008
Hormonal regulation of beta2-adrenergic receptor level in prostate cancer
Prostate, 68 (10), 1133-42
DOI 10.1002/pros.20778, PubMed 18454446
Publications 2006
Androgen dependent regulation of protein kinase A subunits in prostate cancer cells
Cell Signal, 19 (2), 401-9
DOI 10.1016/j.cellsig.2006.07.011, PubMed 16949795
Publications 2005
Expression of serotonin receptors 2B and 4 in human prostate cancer tissue and effects of their antagonists on prostate cancer cell lines
Eur Urol, 47 (6), 895-900
DOI 10.1016/j.eururo.2005.02.006, PubMed 15925089
[Markers for diagnosis, prediction and prognosis of prostate cancer]
Tidsskr Nor Laegeforen, 125 (23), 3279-82
PubMed 16327854
Publications 2004
Serotonin receptor antagonists inhibit proliferation of prostate cancer cells
In European urology supplements, Elsevier Science, Oxford, 3(2004)2, Abstrakt 364
BIBSYS 052053563
Beta2-adrenergic receptor regulation in prostate cancer upon androgen deprivation
In European urology supplements, Elsevier Science, Oxford, 3(2004)2, Abstrakt 581
BIBSYS 052053962
Publications 2003
Protein kinase A-anchoring protein AKAP95 interacts with MCM2, a regulator of DNA replication
J Biol Chem, 278 (29), 26750-6
DOI 10.1074/jbc.M300765200, PubMed 12740381
Protein kinase A-anchoring protein AKAP95 interacts with MCM2: a regulator of DNA replication
In Journal of biological chemistry, The Society, Bethesda, Md., 278(2003)29, s.26750-6
BIBSYS 041732448
Publications 2002
Mechanisms of FOXC2- and FOXD1-mediated regulation of theRI alpha subunit of cAMP-dependent protein kinase include release of transcriptional repression and activation by proteinkinase B alpha and cAMP
In Journal of biological chemistry, The Society, Bethesda, Md., 277(2002)nr.25, S. 22902-8
BIBSYS 031080715
Mechanisms of FOXC2- and FOXD1-mediated regulation of the RI alpha subunit of cAMP-dependent protein kinase include release of transcriptional repression and activation by protein kinase B alpha and cAMP
J Biol Chem, 277 (25), 22902-8
DOI 10.1074/jbc.M200131200, PubMed 11943768
USF2 inhibits C/EBP-mediated transcriptional regulation of the RIIbeta subunit of cAMP-dependent protein kinase
BMC Mol Biol, 3, 10
DOI 10.1186/1471-2199-3-10, PubMed 12086590
Distinct but overlapping domains of AKAP95 are implicated in chromosome condensation and condensin targeting
EMBO Rep, 3 (5), 426-32
DOI 10.1093/embo-reports/kvf089, PubMed 11964380
Distinct but overlapping domains of AKAP95 are implicatedin chromosome condensation and condensin targeting
In EMBO reports, Nature Publ. Group, London, 3(2002)nr.5, S. 426-32
BIBSYS 031080707
Publications 2001
Cyclic AMP regulates expression of the RI alpha subunit of cAMP-dependent protein kinase through an alternatively spliced 5' UTR
In European journal of biochemistry, Blackwell, Oxford, 268(2001)22, s. 5920-9
BIBSYS 022074228
Cyclic AMP regulates expression of the RI alpha subunit of cAMP-dependent protein kinase through an alternatively spliced 5' UTR
Eur J Biochem, 268 (22), 5920-9
DOI 10.1046/j.0014-2956.2001.02542.x, PubMed 11722580
Novel alternatively spliced mRNA (1c) of the protein kinase A RIα subunit is implicated in haploid germ cell specific expression
Mol Reprod Dev, 59 (1), 11-6
DOI 10.1002/mrd.1001, PubMed 11335941
Novel alternatively spliced mRNA (1c) of the protein kinase A RIα subunit is implicated in haploid germ cell specific expression
In Biology of reproduction, Academic Press, New York, 59(2001)nr. 1, s. 11-16
BIBSYS 022078061
Phosphodiesterase 4D and protein kinase a type II constitute a signaling unit in the centrosomal area
J Biol Chem, 276 (25), 21999-2002
DOI 10.1074/jbc.C000911200, PubMed 11285255
Phosphodiesterase 4D and protein kinase a type II constitute a signaliling unit in the centrosomal area
In Journal of biological chemistry, The Society, Bethesda, Md., 276(2001)nr. 25, s. 21999-2002
BIBSYS 022078673
Publications 2000
Regulation of tissue inhibitor of metalloproteinases-1 in rat Sertoli cells: induction by germ cell residual bodies, interleukin-1alpha, and second messengers
Biol Reprod, 62 (4), 1040-6
DOI 10.1095/biolreprod62.4.1040, PubMed 10727275
Publications 1999
Method of transfection affects the cAMP-mediated induction of the RIIbeta subunit of protein kinase A in Sertoli cells: inhibition of response by increase in intracellullar calcium
Eur J Endocrinol, 141 (1), 75-82
DOI 10.1530/eje.0.1410075, PubMed 10407227
Isoform-specific regulation of the CCAAT/enhancer-binding protein family of transcription factors by 3',5'-cyclic adenosine monophosphate in Sertoli cells
Endocrinology, 140 (2), 835-43
DOI 10.1210/endo.140.2.6526, PubMed 9927313
Calcium/phospholipid-dependent protein kinases in rat Sertoli cells: regulation of androgen receptor messenger ribonucleic acid
Biol Reprod, 60 (5), 1257-62
DOI 10.1095/biolreprod60.5.1257, PubMed 10208993
Publications 1997
Characterization of the 5'-flanking region of the gene for the cAMP-inducible protein kinase A subunit, RIIbeta, in Sertoli cells
Mol Cell Endocrinol, 129 (1), 101-14
DOI 10.1016/s0303-7207(97)04045-8, PubMed 9175634
Structure, function, and regulation of human cAMP-dependent protein kinases
Adv Second Messenger Phosphoprotein Res, 31, 191-204
DOI 10.1016/s1040-7952(97)80019-5, PubMed 9344252
Publications 1996
Regulation of protein kinase A subunits by cyclic adenosine 3',5'-monophosphate in a mouse Sertoli cell line (MSC-1): induction of RII beta messenger ribonucleic acid is independent of continuous protein synthesis
Biol Reprod, 55 (1), 5-10
DOI 10.1095/biolreprod55.1.5, PubMed 8793051
Publications 1995
The alpha-subunit mRNAs for Gs and Go2 are differentially regulated by protein kinase A and protein kinase C in rat Sertoli cells
Biochim Biophys Acta, 1260 (3), 269-75
DOI 10.1016/0167-4781(94)00203-f, PubMed 7873600
Publications 1993
Protein kinase C activation and positive and negative agonist regulation of 3',5'-cyclic adenosine monophosphate levels in cultured rat Sertoli cells
Acta Endocrinol (Copenh), 128 (6), 568-72
DOI 10.1530/acta.0.1280568, PubMed 7687809
Reciprocal regulation of mRNA and protein for subunits of cAMP-dependent protein kinase (RI alpha and C alpha) by cAMP in a neoplastic B cell line (Reh)
J Biol Chem, 268 (31), 23483-9
PubMed 8226875
Publications 1992
Inhibitors of RNA and protein synthesis stabilize messenger RNA for the RII beta subunit of protein kinase A in different cellular compartments
Biochem Biophys Res Commun, 183 (2), 632-9
DOI 10.1016/0006-291x(92)90529-t, PubMed 1550570
Half-lives of different sized mRNAs for the PKA subunit RI alpha are regulated differently in response to inhibition of transcription and translation
Biochem Biophys Res Commun, 184 (1), 454-60
DOI 10.1016/0006-291x(92)91215-c, PubMed 1314594
The cAMP signal transduction pathway in cultured rat Sertoli cells: molecular mechanisms for protein kinase A and protein kinase C dependent regulation of gene expression
Institute of Medical Biochemistry, University of Oslo, Oslo, 1 b. (flere pag.)
BIBSYS 931140978, ISBN 82-992860-1-8
Protein kinase C activation by 12-O-tetradecanoylphorbol 13-acetate modulates messenger ribonucleic acid levels for two of the regulatory subunits of 3',5'-cyclic adenosine monophosphate-dependent protein kinases (RII beta and RI alpha) via multiple and distinct mechanisms
Endocrinology, 130 (3), 1271-80
DOI 10.1210/endo.130.3.1311233, PubMed 1311233
Publications 1991
Adenosine 3',5'-monophosphate-dependent stabilization of messenger ribonucleic acids (mRNAs) for protein kinase-A (PKA) subunits in rat Sertoli cells: rapid degradation of mRNAs for PKA subunits is dependent on ongoing RNA and protein synthesis
Endocrinology, 129 (5), 2496-502
DOI 10.1210/endo-129-5-2496, PubMed 1657577
Different mechanisms are involved in cAMP-mediated induction of mRNAs for subunits of cAMP-dependent protein kinases
Mol Endocrinol, 5 (1), 21-8
DOI 10.1210/mend-5-1-21, PubMed 1850108