Yngvar Fløisand

  • Consultant; PhD
  • +47 23 07 24 62
 

Publications 2021

Ali MM, Gronvold B, Remberger M, Abrahamsen IW, Myhre AE, Tjonnfjord GE, Floisand Y, Gedde-Dahl T (2021)
Addition of Anti-thymocyte Globulin in Allogeneic Stem Cell Transplantation With Peripheral Stem Cells From Matched Unrelated Donors Improves Graft-Versus-Host Disease and Relapse Free Survival
Clin. Lymphoma Myeloma Leuk., 21 (9), 598-605
DOI 10.1016/j.clml.2021.05.003

Berishvili E, Kaiser L, Cohen M, Berney T, Scholz H, Floisand Y, Mattsson J (2021)
Treatment of COVID-19 Pneumonia: the Case for Placenta-derived Cell Therapy
Stem Cell Rev. Rep., 17 (1), 63-70
DOI 10.1007/s12015-020-10004-x

Floisand Y, Schroeder MA, Chevallier P, Selleslag D, Devine S, Renteria AS, Mohty M, Yakoub-Agha I, Chen CL, Parfionovas A, Quadri S, Jansson J, Akbari M, Chen YB (2021)
A phase 2a randomized clinical trial of intravenous vedolizumab for the treatment of steroid-refractory intestinal acute graft-versus-host disease
Bone Marrow Transplant., 56 (10), 2477-2488
DOI 10.1038/s41409-021-01356-0

Jorgensen SF, Buechner J, Myhre AE, Galteland E, Spetalen S, Kulseth MA, Sorte HS, Holla OL, Lundman E, Alme C, Heier I, Flaegstad T, Floisand Y, Benneche A, Fevang B, Aukrust P, Stray-Pedersen A, Gedde-Dahl T, Nordoy I (2021)
A Nationwide Study of GATA2 Deficiency in Norway-the Majority of Patients Have Undergone Allo-HSCT
J. Clin. Immunol.
DOI 10.1007/s10875-021-01189-y

Lowenberg B, Pabst T, Maertens J, Gradowska P, Biemond BJ, Spertini O, Vellenga E, Griskevicius L, Tick LW, Jongen-Lavrencic M, Kooy MV, Vekemans MC, van der Velden WJFM, Beverloo B, Michaux L, Graux C, Deeren D, de Weerdt O, van Esser JWJ, Bargetzi M, Klein SK, Gadisseur A, Westerweel PE, Veelken H, Gregor M et al. (2021)
Addition of lenalidomide to intensive treatment in younger and middle-aged adults with newly diagnosed AML: the HOVON-SAKK-132 trial
Blood Adv., 5 (4), 1110-1121
DOI 10.1182/bloodadvances.2020003855

Quiles-Jimenez A, Gregersen I, Segers FM, Skarpengland T, Kroustallaki P, Yang K, Kong XY, Lauritzen KH, Olsen MB, Karlsen TR, Nyman TA, Sagen EL, Bjerkeli V, Suganthan R, Nygard S, Scheffler K, Prins J, Van der Veer E, Ogaard JDS, Floisand Y, Jorgensen HF, Holven KB, Biessen EA, Nilsen H, Dahl TB et al. (2021)
DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development
Atherosclerosis, 324, 123-132
DOI 10.1016/j.atherosclerosis.2021.02.023

Remberger M, Tjonnfjord GE, Abrahamsen IW, Ali M, Myhre AE, Gedde-Dahl T, Floisand Y (2021)
Superior Graft-versus-Host Disease-Free Relapse-Free Survival in Matched Unrelated Donor Hematopoietic Stem Cell Transplantation with Anti-Thymocyte Globulin (ATG) Compared to Matched Related Donor without ATG
Transpl. Cell. Ther., 27 (7)
DOI 10.1016/j.jtct.2021.03.019

Tadele DS, Robertson J, Crispin R, Herrera MC, Chlubnova M, Piechaczyk L, Ayuda-Duran P, Singh SK, Gedde-Dahl T, Floisand Y, Skavland J, Wesche J, Gjertsen BT, Enserink JM (2021)
A cell competition-based small molecule screen identifies a novel compound that induces dual c-Myc depletion and p53 activation
J. Biol. Chem., 296, 100179
DOI 10.1074/jbc.RA120.015285

Publications 2020

Bazarbachi A, Bug G, Baron F, Brissot E, Ciceri F, Abou Dalle I, Dohner H, Esteve J, Floisand Y, Giebel S, Gilleece M, Gorin NC, Jabbour E, Aljurf M, Kantarjian H, Kharfan-Dabaja M, Labopin M, Lanza F, Malard F, Peric Z, Prebet T, Ravandi F, Ruggeri A, Sanz J, Schmid C et al. (2020)
Clinical practice recommendation on hematopoietic stem cell transplantation for acute myeloid leukemia patients with FLT3-internal tandem duplication: a position statement from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation
Haematologica, 105 (6), 1507-1516
DOI 10.3324/haematol.2019.243410

Derolf A, Juliusson G, Benson L, Floisand Y, Lazarevic V, Antunovic P, Mollgard L, Lehmann S, Uggla B, Wahlin A, Hoglund M, Deneberg S (2020)
Decreasing early mortality in acute myeloid leukaemia in Sweden 1997-2014: improving performance status is a major contributing factor
Br. J. Haematol., 188 (1), 187-191
DOI 10.1111/bjh.16265

Gronvold B, Ali MM, Remberger M, Mattsson J, Egeland T, Lundin KU, Myhre AE, Abrahamsen IW, Heldal D, Dybedal I, Tjonnfjord GE, Floisand Y, Gedde-Dahl T (2020)
HLA-DPB1 mismatch reduce relapse and improve survival in T-cell replete unrelated donor allogeneic stem cell transplantation
Bone Marrow Transplant., 55 (8), 1658-1661
DOI 10.1038/s41409-020-0827-3

Spyridonidis A, Labopin M, Savani BN, Niittyvuopio R, Blaise D, Craddock C, Socie G, Platzbecker U, Beelen D, Milpied N, Cornelissen JJ, Ganser A, Huynh A, Griskevicius L, Giebel S, Brissot E, Malard F, Esteve J, Peric Z, Baron F, Ruggeri A, Schmid C, Gilleece M, Gorin NC, Lanza F et al. (2020)
Redefining and measuring transplant conditioning intensity in current era: a study in acute myeloid leukemia patients
Bone Marrow Transplant., 55 (6), 1114-1125
DOI 10.1038/s41409-020-0803-y

Publications 2019

Danylesko I, Bukauskas A, Paulson M, Peceliunas V, Gedde-Dahl T, Shimoni A, Shouval R, Griskevicius L, Floisand Y, Nagler A (2019)
Anti-a4 beta 7 integrin monoclonal antibody (vedolizumab) for the treatment of steroid-resistant severe intestinal acute graft-versus-host disease
Bone Marrow Transplant., 54 (7), 987-993
DOI 10.1038/s41409-018-0364-5

Floisand Y, Lazarevic VL, Maertens J, Mattsson J, Shah NN, Zachee P, Taylor A, Akbari M, Quadri S, Parfionovas A, Chen YB (2019)
Safety and Effectiveness of Vedolizumab in Patients with Steroid- Refractory Gastrointestinal Acute Graft-versus-Host Disease: A Retrospective Record Review
Biol. Blood Marrow Transplant., 25 (4), 720-727
DOI 10.1016/j.bbmt.2018.11.013

Sioud M, Pettersen S, Ailte I, Floisand Y (2019)
Targeted Killing of Monocytes/Macrophages and Myeloid Leukemia Cells with Pro-Apoptotic Peptides
Cancers, 11 (8), 1088
DOI 10.3390/cancers11081088

Thomas AM, Gerogianni A, McAdam MB, Floisand Y, Lau C, Espevik T, Nilsson PH, Mollnes TE, Barratt-Due A (2019)
Complement Component C5 and TLR Molecule CD14 Mediate Heme-Induced Thromboinflammation in Human Blood
J. Immunol., 203 (6), 1571-1578
DOI 10.4049/jimmunol.1900047

Zhang BB, Ayuda-Duran P, Piechaczyk L, Floisand Y, Safont MM, Karlsen IT, Fandalyuk Z, Tadele D, van Mierlo P, Rowe AD, Robertson JM, Gjertsen BT, McCormack E, Enserink JM (2019)
RETRACTION: GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells (Retraction of 10.3324/HAEMATOL.2018.189399, 2018)
Haematologica, 104 (5), E229
DOI 10.3324/haematol.2019.220533

Publications 2018

Diep PP, Melberg HO, Brinch L, Buechner J, Floisand Y, Gedde-Dahl T, Loge JH, Tjonnfjord GE, Ruud E (2018)
Cost-utility of allogeneic hematopoietic stem cell transplantation in Norway
Bone Marrow Transplant., 53 (5), 657-660
DOI 10.1038/s41409-018-0091-y

Ringden O, Labopi M, Sadeghi B, Mailhol A, Beelen D, Floisand Y, Ghavamzadeh A, Finke J, Ehninger G, Volin L, Socie G, Kroger N, Stuhler G, Ganser A, Schmid C, Giebel S, Mohty M, Nagler A (2018)
What is the outcome in patients with acute leukaemia who survive severe acute graft-versus-host disease?
J. Intern. Med., 283 (2), 166-177
DOI 10.1111/joim.12695

Sioud M, Westby P, Vasovic V, Floisand Y, Peng Q (2018)
Development of a new high-affinity human antibody with antitumor activity against solid and blood malignancies
Faseb J., 32 (9), 5063-5077
DOI 10.1096/fj.201701544R

Publications 2017

Floisand Y, Lundin KEA, Lazarevic V, Kristiansen JD, Osnes LTN, Tjonnfjord GE, Reims HM, Gedde-Dahl T (2017)
Targeting Integrin alpha 4 beta 7 in Steroid-Refractory Intestinal Graft-versus-Host Disease
Biol. Blood Marrow Transplant., 23 (1), 172-175
DOI 10.1016/j.bbmt.2016.10.009

Gustavsen A, Skattum L, Bergseth G, Lorentzen B, Floisand Y, Bosnes V, Mollnes TE, Barratt-Due A (2017)
Effect on mother and child of eculizumab given before caesarean section in a patient with severe antiphospholipid syndrome A case report
Medicine (Baltimore), 96 (11), e6338
DOI 10.1097/MD.0000000000006338

Kontro M, Kumar A, Majumder MM, Eldfors S, Parsons A, Pemovska T, Saarela J, Yadav B, Malani D, Floisand Y, Hoglund M, Remes K, Gjertsen BT, Kallioniemi O, Wennerberg K, Heckman CA, Porkka K (2017)
HOX gene expression predicts response to BCL-2 inhibition in acute myeloid leukemia
Leukemia, 31 (2), 301-309
DOI 10.1038/leu.2016.222

Server A, Bargallo N, Floisand Y, Sponheim J, Graus F, Hald JK (2017)
Imaging spectrum of central nervous system complications of hematopoietic stem cell and solid organ transplantation.
Neuroradiology, 59 (2), 105-126
DOI 10.1007/s00234-017-1804-4

Torfoss D, Fladhagen T, Holte H, Brinch L, Schjesvold FH, Floisand Y, Nyquist E, Dalgaard J, Meyer P, Lehmann AK, Hammerstrom J, Skjelbakken T, Hoiby EA, Sandvik L, Kvaloy S (2017)
Benzylpenicillin plus an aminoglycoside versus meropenem in neutropenic lymphoma and leukaemia patients with a suspected bacterial infection: a randomized, controlled trial
Clin. Microbiol. Infect., 23 (3), 179-187
DOI 10.1016/j.cmi.2016.10.019

Wang D, Floisand Y, Myklebust CV, Burgler S, Parente-Ribes A, Hofgaard PO, Bogen B, Tasken K, Tjonnfjord GE, Schjesvold F, Dalgaard J, Tveita A, Munthe LA (2017)
Autologous bone marrow Th cells can support multiple myeloma cell proliferation in vitro and in xenografted mice
Leukemia, 31 (10), 2114-2121
DOI 10.1038/leu.2017.69

Publications 2016

Barratt-Due A, Floisand Y, Orrem HL, Kvam AK, Holme PA, Bergseth G, Tjonnfjore GE, Mollnes TE (2016)
Complement activation is a crucial pathogenic factor in catastrophic antiphospholipid syndrome
RHEUMATOLOGY, 55 (7), 1337-1340
DOI 10.1093/rheumatology/kew040

Wennstrom L, Edslev PW, Abrahamsson J, Norgaard JM, Floisand Y, Forestier E, Gustafsson G, Heldrup J, Hovi L, Jahnukainen K, Jonsson OG, Lausen B, Palle J, Zeller B, Holmberg E, Juliusson G, Stockelberg D, Hasle H, Nordic Soc Paediatric Haematology Danish Acute Leukemia Grp Swedish Acute Myeloid Leukemia Grp (2016)
Acute Myeloid Leukemia in Adolescents and Young Adults Treated in Pediatric and Adult Departments in the Nordic Countries
Pediatr. Blood Cancer, 63 (1), 83-92
DOI 10.1002/pbc.25713

Publications 2015

Bremer S, Floisand Y, Brinch L, Gedde-Dahl T, Bergan S (2015)
Glutathione Transferase Gene Variants Influence Busulfan Pharmacokinetics and Outcome After Myeloablative Conditioning
Ther. Drug Monit., 37 (4), 493-500
DOI 10.1097/FTD.0000000000000180

Hoyvoll LR, Floisand Y, Orrem HL, Gunnarsson R, Landro L, Brevig T, Gaustad P, Nordoy I (2015)
Hemophagocytic lymphohistiocytosis in leprosy
Lepr. Rev., 86 (4), 403-406

Publications 2014

Kristiansen HA, Spetalen S, Floisand Y, Heldal D (2014)
Eltrombopag in Good's Syndrome
Case Rep. Hematol., 2014, 172139
DOI 10.1155/2014/172139

Taraldsrud E, Fevang B, Aukrust P, Beiske KH, Floisand Y, Froland S, Rollag H, Olweus J (2014)
Common variable immunodeficiency revisited: normal generation of naturally occurring dendritic cells that respond to Toll-like receptors 7 and 9
Clin. Exp. Immunol., 175 (3), 439-448
DOI 10.1111/cei.12239

Publications 2013

Cesaro S, Pillon M, Tridello G, Aljurf M, Martino R, Schroyens W, Nozzoli C, Barba P, Faraci M, Fagioli F, Cappelli B, Cordonnier C, Al-Mohareb F, Floisand Y, Greil J, Panizzolo IS, Santarone S (2013)
Relationship between clinical and BK virological response in patients with late hemorrhagic cystitis treated with cidofovir: a retrospective study from the European Group for Blood and Marrow Transplantation
Bone Marrow Transplant., 48 (6), 809-813
DOI 10.1038/bmt.2012.247

Fernandes AM, Herlofsen SR, Karlsen TA, Kuchler AM, Floisand Y, Brinchmann JE (2013)
Similar Properties of Chondrocytes from Osteoarthritis Joints and Mesenchymal Stem Cells from Healthy Donors for Tissue Engineering of Articular Cartilage
PLoS One, 8 (5), e62994
DOI 10.1371/journal.pone.0062994

Floisand Y, Beiske K, Tjonnfjord GE, Heldal D, Bjerkehagen B, Revheim ME, Heim S, Bruland OS, Hall KS, Tierens A, Delabie J (2013)
Malignant Phyllodes Tumor and Acute Megakaryoblastic Leukemia Sharing a Common Clonal Origin
Case Rep. Hematol., 2013, 934781
DOI 10.1155/2013/934781

Holm AM, Riise GC, Hansson L, Brinch L, Bjortuft O, Iversen M, Simonsen S, Floisand Y (2013)
Lung transplantation for bronchiolitis obliterans syndrome after allo-SCT
Bone Marrow Transplant., 48 (5), 703-707
DOI 10.1038/bmt.2012.197

Holm M, Riise GC, Brinch L, Bjortuft O, Iversen M, Simonsen S, Floisand Y (2013)
Lung Transplantation for Bronchiolitis Obliterans After Allogeneic Hematopoietic Stem Cell Transplantation: Unresolved Questions
Transplantation, 96 (4), E21-E22
DOI 10.1097/TP.0b013e31829df2c0

Publications 2012

Floisand Y, Brinch L, Gedde-Dahl T, Tjonnfjord GE, Dybedal I, Holte H, Heldal D, Torfoss D, Aurlien E, Lauritzsen GF, Fossa A, Lehne G, Baggerod E, Kvalheim G, Egeland T, Bishop MR, Fowler DH, Kolstad A (2012)
Ultra-short course sirolimus contributes to effective GVHD prophylaxis after reduced-intensity allogeneic hematopoietic cell transplantation
Bone Marrow Transplant., 47 (12), 1552-1557
DOI 10.1038/bmt.2012.63

Publications 2011

Floisand Y, Delabie J, Fossa A, Helseth E, Jacobsen EA, Rolke J, Tjonnfjord GE (2011)
Richter syndrome presenting as a solitary cerebellar tumor during first-line treatment for chronic lymphocytic leukemia
Leuk. Lymphoma, 52 (10), 2007-2009
DOI 10.3109/10428194.2011.580480

Karlsen TA, Mirtaheri P, Shandadfar A, Floisand Y, Brinchmann JE (2011)
Effect of Three-Dimensional Culture and Incubator Gas Concentration on Phenotype and Differentiation Capability of Human Mesenchymal Stem Cells
J. Cell. Biochem., 112 (2), 684-693
DOI 10.1002/jcb.22978

Sioud M, Mobergslien A, Boudabous A, Floisand Y (2011)
Mesenchymal stem cell-mediated T cell suppression occurs through secreted galectins
Int. J. Oncol., 38 (2), 385-390
DOI 10.3892/ijo.2010.869

Publications 2010

Fløisand Y (2010)
Studies on dendritic cell ontogeny, differentiation and function
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 959, 1 b. (flere pag.)
BIBSYS 101339860, ISBN 978-82-8072-361-1

Sioud M, Mobergslien A, Boudabous A, Floisand Y (2010)
Evidence for the Involvement of Galectin-3 in Mesenchymal Stem Cell Suppression of Allogeneic T-Cell Proliferation
Scand. J. Immunol., 71 (4), 267-274
DOI 10.1111/j.1365-3083.2010.02378.x

Publications 2009

Damas JK, Landro L, Fevang B, Heggelund L, Tjonnfjord GE, Floisand Y, Halvorsen B, Froland SS, Aukrust P (2009)
Homeostatic chemokines CCL19 and CCL21 promote inflammation in human immunodeficiency virus-infected patients with ongoing viral replication
Clin. Exp. Immunol., 157 (3), 400-407
DOI 10.1111/j.1365-2249.2009.03976.x

Sioud M, Floisand Y (2009)
NOD2/CARD15 on bone marrow CD34+hematopoietic cells mediates induction of cytokines and cell differentiation
J. Leukoc. Biol., 85 (6), 939-946
DOI 10.1189/jlb.1008650

Publications 2008

Floisand Y, Normann AP, Heim S, Lund-Johansen F, Tjonnfjord GE (2008)
High expression of CD7 on CD34(+) cells is not linked to deletion of derivative chromosome 9 or lack of dendritic cells in chronic myeloid leukaemia
Scand. J. Clin. Lab. Invest., 68 (2), 93-98
DOI 10.1080/00365510701558477

Furset G, Floisand Y, Sioud M (2008)
Impaired expression of indoleamine 2, 3-dioxygenase in monocyte-derived dendritic cells in response to Toll-like receptor-7/8 ligands
Immunology, 123 (2), 263-271
DOI 10.1111/j.1365-2567.2007.02695.x

Publications 2007

Kvale EO, Floisand Y, Lund-Johansen F, Rollag H, Farkas L, Ghanekar S, Brandtzaeg P, Jahnsen FL, Olweus J (2007)
Plasmacytoid DCs regulate recall responses by rapid induction of IL-10 in memory T cells
Blood, 109 (8), 3369-3376
DOI 10.1182/blood-2006-06-031484

Sioud M, Floisand Y (2007)
TLR agonists induce the differentiation of human bone marrow CD34(+) progenitors into CD11c(+) CD80/86(+) DC capable of inducing a Th1-type response
Eur. J. Immunol., 37 (10), 2834-2846
DOI 10.1002/eji.200737112

Publications 2006

Sioud M, Floisand Y, Forfang U, Lund-Johansen F (2006)
Signaling through toll-like receptor 7/8 induces the differentiation of human bone marrow CD34+progenitor cells along the myeloid lineage
J. Mol. Biol., 364 (5), 945-954
DOI 10.1016/j.jmb.2006.09.054