Helga Sanner
- Group leader, Professor; MD, PhD
- +47 412 56 664
Research interests
I have a broad background in clinical, translational, and epidemiological research, with a primary focus on juvenile-onset rheumatic diseases. My dedication lies in advancing our understanding of environmental risk factors, gene-environment interactions, disease mechanisms and prognosis in this context to ultimately improve patient care and outcomes.
PROJECTS: PREVENT-JIA, NorJDM, Physical fitness in JIA, PREDICT-JIA, MyJIA, NorChildCTD, NorSLE, translation of PROMIS tools, several international collaborative projects
Publications 2024
A protocol for scoping reviews on the role of whole-body and dedicated body-part magnetic resonance imaging for assessment of adult and juvenile idiopathic inflammatory myopathies
Rheumatol Int, 44 (11), 2403-2409
DOI 10.1007/s00296-024-05649-7, PubMed 38976028
Sensitivity of classification criteria from time of diagnosis in an incident systemic lupus erythematosus cohort: a population-based study from Norway
RMD Open, 10 (3)
DOI 10.1136/rmdopen-2024-004395, PubMed 39160088
Incidence and Genetic Risk of Juvenile Idiopathic Arthritis in Norway by Latitude
Arthritis Rheumatol (in press)
DOI 10.1002/art.43040, PubMed 39431377
Publications 2023
Cardiac dysfunction in mixed connective tissue disease: a nationwide observational study
Rheumatol Int, 43 (6), 1055-1065
DOI 10.1007/s00296-023-05308-3, PubMed 36933069
Antibiotic exposure in prenatal and early life and risk of juvenile idiopathic arthritis: a nationwide register-based cohort study
RMD Open, 9 (3)
DOI 10.1136/rmdopen-2023-003333, PubMed 37648397
Adipokine profile in long-term juvenile dermatomyositis, and associations with adipose tissue distribution and cardiac function: a cross-sectional study
RMD Open, 9 (1)
DOI 10.1136/rmdopen-2022-002815, PubMed 36828644
Adipose tissue distribution is associated with cardio-metabolic alterations in adult patients with juvenile-onset dermatomyositis
Rheumatology (Oxford), 62 (SI2), SI196-SI204
DOI 10.1093/rheumatology/keac293, PubMed 35575380
Publications 2022
Association with HLA-DRβ1 position 37 distinguishes juvenile dermatomyositis from adult-onset myositis
Hum Mol Genet, 31 (14), 2471-2481
DOI 10.1093/hmg/ddac019, PubMed 35094092
Anakinra in Patients With Systemic Juvenile Idiopathic Arthritis: Long-term Safety From the Pharmachild Registry
J Rheumatol, 49 (4), 398-407
DOI 10.3899/jrheum.210563, PubMed 35105709
Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset
Ann Rheum Dis, 81 (8), 1085-1095
DOI 10.1136/annrheumdis-2021-221754, PubMed 35470158
Validity and Reliability of Four Parent/Patient-Reported Outcome Measures for Juvenile Idiopathic Arthritis Remote Monitoring
Arthritis Care Res (Hoboken), 75 (2), 391-400
DOI 10.1002/acr.24855, PubMed 35015379
Body composition in long-standing juvenile dermatomyositis: associations with disease activity, muscle strength and cardiometabolic measures
Rheumatology (Oxford), 61 (7), 2959-2968
DOI 10.1093/rheumatology/keab805, PubMed 34718443
Associations between cardiac and pulmonary involvement in patients with juvenile dermatomyositis-a cross-sectional study
Rheumatol Int, 42 (7), 1213-1220
DOI 10.1007/s00296-021-05071-3, PubMed 34984516
Publications 2021
Bone mineral density and explanatory factors in children and adults with juvenile dermatomyositis at long term follow-up; a cross sectional study
Pediatr Rheumatol Online J, 19 (1), 56
DOI 10.1186/s12969-021-00543-z, PubMed 33902632
Publications 2020
Functional and Structural Adaptations of Skeletal Muscle in Long-Term Juvenile Dermatomyositis: A Controlled Cross-Sectional Study
Arthritis Rheumatol, 72 (5), 837-848
DOI 10.1002/art.41174, PubMed 31746550
Opportunistic infections in immunosuppressed patients with juvenile idiopathic arthritis: analysis by the Pharmachild Safety Adjudication Committee
Arthritis Res Ther, 22 (1), 71
DOI 10.1186/s13075-020-02167-2, PubMed 32264969
Novel associations between cytokines and pulmonary involvement in juvenile dermatomyositis - a cross-sectional study of long-term disease
Rheumatology (Oxford), 59 (8), 1862-1870
DOI 10.1093/rheumatology/kez531, PubMed 31740970
Publications 2019
Association Between Nailfold Capillary Density and Pulmonary and Cardiac Involvement in Medium to Longstanding Juvenile Dermatomyositis
Arthritis Care Res (Hoboken), 71 (4), 492-497
DOI 10.1002/acr.23687, PubMed 29953739
Cardiorespiratory fitness in long-term juvenile dermatomyositis: a controlled, cross-sectional study of active/inactive disease
Rheumatology (Oxford), 58 (3), 492-501
DOI 10.1093/rheumatology/key342, PubMed 30508195
Cardiovascular rEmodelling in living kidNey donorS with reduced glomerular filtration rate: rationale and design of the CENS study
Blood Press, 29 (2), 123-134
DOI 10.1080/08037051.2019.1684817, PubMed 31718316
Physical Fitness in Patients With Oligoarticular and Polyarticular Juvenile Idiopathic Arthritis Diagnosed in the Era of Biologics: A Controlled Cross-Sectional Study
Arthritis Care Res (Hoboken), 71 (12), 1611-1620
DOI 10.1002/acr.23818, PubMed 30474929
Measurement properties and performance of an eight-minute submaximal treadmill test in patients with juvenile idiopathic arthritis: a controlled study
Pediatr Rheumatol Online J, 17 (1), 14
DOI 10.1186/s12969-019-0316-7, PubMed 30961626
Effect on Cardiac Function of Longstanding Juvenile-onset Mixed Connective Tissue Disease: A Controlled Study
J Rheumatol, 46 (7), 739-747
DOI 10.3899/jrheum.180526, PubMed 30877222
Publications 2018
Assessment of Microvascular Abnormalities by Nailfold Capillaroscopy in Juvenile Dermatomyositis After Medium- to Long-Term Followup
Arthritis Care Res (Hoboken), 70 (5), 768-776
DOI 10.1002/acr.23338, PubMed 28805016
Physical activity in patients with oligo- and polyarticular juvenile idiopathic arthritis diagnosed in the era of biologics: a controlled cross-sectional study
Pediatr Rheumatol Online J, 16 (1), 64
DOI 10.1186/s12969-018-0281-6, PubMed 30333025
Publications 2017
Submaximal Exercise Capacity in Juvenile Dermatomyositis after Longterm Disease: The Contribution of Muscle, Lung, and Heart Involvement
J Rheumatol, 44 (6), 827-834
DOI 10.3899/jrheum.160997, PubMed 28365577
EULAR/ACR classification criteria for adult and juvenile idiopathic inflammatory myopathies and their major subgroups: a methodology report
RMD Open, 3 (2), e000507
DOI 10.1136/rmdopen-2017-000507, PubMed 29177080
2017 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Adult and Juvenile Idiopathic Inflammatory Myopathies and Their Major Subgroups
Arthritis Rheumatol, 69 (12), 2271-2282
DOI 10.1002/art.40320, PubMed 29106061
2017 European League Against Rheumatism/American College of Rheumatology classification criteria for adult and juvenile idiopathic inflammatory myopathies and their major subgroups
Ann Rheum Dis, 76 (12), 1955-1964
DOI 10.1136/annrheumdis-2017-211468, PubMed 29079590
Development and Initial Validation of the Macrophage Activation Syndrome/Primary Hemophagocytic Lymphohistiocytosis Score, a Diagnostic Tool that Differentiates Primary Hemophagocytic Lymphohistiocytosis from Macrophage Activation Syndrome
J Pediatr, 189, 72-78.e3
DOI 10.1016/j.jpeds.2017.06.005, PubMed 28807357
Publications 2016
Cardiac involvement in adult and juvenile idiopathic inflammatory myopathies
RMD Open, 2 (2), e000291
DOI 10.1136/rmdopen-2016-000291, PubMed 27752355
Publications 2015
In juvenile dermatomyositis, heart rate variability is reduced, and associated with both cardiac dysfunction and markers of inflammation: a cross-sectional study median 13.5 years after symptom onset
Rheumatology (Oxford), 55 (3), 535-43
DOI 10.1093/rheumatology/kev376, PubMed 26500284
Publications 2014
Severe macrophage activation syndrome and central nervous system involvement in juvenile dermatomyositis
Scand J Rheumatol, 43 (2), 171-3
DOI 10.3109/03009742.2013.863968, PubMed 24588361
Clinical features, treatment, and outcome of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis: a multinational, multicenter study of 362 patients
Arthritis Rheumatol, 66 (11), 3160-9
DOI 10.1002/art.38802, PubMed 25077692
Increased levels of eotaxin and MCP-1 in juvenile dermatomyositis median 16.8 years after disease onset; associations with disease activity, duration and organ damage
PLoS One, 9 (3), e92171
DOI 10.1371/journal.pone.0092171, PubMed 24647150
Disease activity and prognostic factors in juvenile dermatomyositis: a long-term follow-up study applying the Paediatric Rheumatology International Trials Organization criteria for inactive disease and the myositis disease activity assessment tool
Rheumatology (Oxford), 53 (9), 1578-85
DOI 10.1093/rheumatology/keu146, PubMed 24692575
In active juvenile dermatomyositis, elevated eotaxin and MCP-1 and cholesterol levels in the upper normal range are associated with cardiac dysfunction
Rheumatology (Oxford), 53 (12), 2214-22
DOI 10.1093/rheumatology/keu256, PubMed 24996906
Publications 2013
In juvenile dermatomyositis, cardiac systolic dysfunction is present after long-term follow-up and is predicted by sustained early skin activity
Ann Rheum Dis, 73 (10), 1805-10
DOI 10.1136/annrheumdis-2013-203279, PubMed 23881732
Publications 2012
Quality of life in adults with juvenile-onset dermatomyositis: a case-control study
Arthritis Care Res (Hoboken), 64 (7), 1020-7
DOI 10.1002/acr.21637, PubMed 22328537
Publications 2011
Outcomes and prognostic factors in juvenile dermatomyositis
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 1064, 1 b. (flere pag.)
BIBSYS 111117275, ISBN 978-82-8072-549-3
Cardiac dysfunction in juvenile dermatomyositis: a case-control study
Ann Rheum Dis, 70 (5), 766-71
DOI 10.1136/ard.2010.137968, PubMed 21216816
Publications 2010
Long-term muscular outcome and predisposing and prognostic factors in juvenile dermatomyositis: A case-control study
Arthritis Care Res (Hoboken), 62 (8), 1103-11
DOI 10.1002/acr.20203, PubMed 20506141
Pulmonary outcome in juvenile dermatomyositis: a case-control study
Ann Rheum Dis, 70 (1), 86-91
DOI 10.1136/ard.2010.131433, PubMed 20805295
Publications 2009
Cumulative organ damage and prognostic factors in juvenile dermatomyositis: a cross-sectional study median 16.8 years after symptom onset
Rheumatology (Oxford), 48 (12), 1541-7
DOI 10.1093/rheumatology/kep302, PubMed 19776224
Publications 1996
Kompendium i hygiene og mikrobiologi
In Kompendium, Medisinsk basislitteratur, Oslo, 6 (7. utg. [sic.]), 160 s.
BIBSYS 962046027, ISBN 82-91562-11-3