Karin Kilian

  • PhD student; MD
  • +47 977 01 208

Research interests

As a clinician and rheumatologist, I have devoted many years to providing quality care to patients. My professional journey led me to a special interest in ANCA vasculitis. While advancements in treatment have significantly enhanced the life expectancy of patients over the last decades, there remains a considerable journey ahead. I embarked on this project with the aim of establishing a population based ANCA vasculitis cohort in Oslo and ultimately to contribute to an improved patient follow up and outcome. 

PROJECT: AAViNor: ANCA associated vasculitides in Oslo


Publications 2022

Zeng L, Walsh M, Guyatt GH, Siemieniuk RAC, Collister D, Booth M, Brown P, Farrar L, Farrar M, Firth T, Fussner LA, Kilian K, Little MA, Mavrakanas TA, Mustafa RA, Piram M, Stamp LK, Xiao Y, Lytvyn L, Agoritsas T, Vandvik PO, Mahr A (2022)
Plasma exchange and glucocorticoid dosing for patients with ANCA-associated vasculitis: a clinical practice guideline
BMJ, 376, e064597
DOI 10.1136/bmj-2021-064597, PubMed 35217581

Publications 2021

Holme SS, Kilian K, Eggesbø HB, Moen JM, Molberg Ø (2021)
Impact of baseline clinical and radiological features on outcome of chronic rhinosinusitis in granulomatosis with polyangiitis
Arthritis Res Ther, 23 (1), 18
DOI 10.1186/s13075-020-02401-x, PubMed 33430923

Publications 2020

Holme SS, Moen JM, Kilian K, Eggesbø HB, Molberg Ø (2020)
Impact of Paranasal Sinus Surgery in Granulomatosis With Polyangiitis: A Longitudinal Computed Tomography Study
Laryngoscope, 130 (8), E460-E468
DOI 10.1002/lary.28639, PubMed 32243590

Publications 2019

Garen T, Lerang K, Hoffmann-Vold AM, Andersson H, Midtvedt Ø, Brunborg C, Kilian K, Gudbrandsson B, Gunnarsson R, Norby G, Chaudhary A, Thoen J, Forseth KØ, Fresjar K, Førre Ø, Haugen M, Haga HJ, Gran JT, Gilboe IM, Molberg Ø, Palm Ø (2019)
Mortality and causes of death across the systemic connective tissue diseases and the primary systemic vasculitides
Rheumatology (Oxford), 58 (2), 313-320
DOI 10.1093/rheumatology/key285, PubMed 30281089

Holme SS, Moen JM, Kilian K, Haukeland H, Molberg Ø, Eggesbø HB (2019)
Development of CT-based methods for longitudinal analyses of paranasal sinus osteitis in granulomatosis with polyangiitis
BMC Med Imaging, 19 (1), 13
DOI 10.1186/s12880-019-0315-7, PubMed 30717680

Publications 2018

Dal Negro G, Eskes C, Belz S, Bertein C, Chlebus M, Corvaro M, Corvi R, Dhalluin S, Halder M, Harvey J, Hermann M, Hoffmann-Dörr S, Kilian K, Lambrigts D, Laroche C, Louhimies S, Mahony C, Manou I, McNamee P, Prieto P, Reid K, Roggen E, Schutte K, Stirling C, Uhlrich S et al. (2018)
One science-driven approach for the regulatory implementation of alternative methods: A multi-sector perspective
Regul Toxicol Pharmacol, 99, 33-49
DOI 10.1016/j.yrtph.2018.08.002, PubMed 30098372

Hoffmann-Vold AM, Fretheim H, Midtvedt Ø, Kilian K, Angelshaug M, Chaudhary A, Gunnarsson R, Brunborg C, Garen T, Andreassen AK, Gude E, Molberg Ø (2018)
Frequencies of borderline pulmonary hypertension before and after the DETECT algorithm: results from a prospective systemic sclerosis cohort
Rheumatology (Oxford), 57 (3), 480-487
DOI 10.1093/rheumatology/kex435, PubMed 29237073

Publications 2011

Wedepohl S, Beceren-Braun F, Riese S, Buscher K, Enders S, Bernhard G, Kilian K, Blanchard V, Dernedde J, Tauber R (2011)
L-selectin--a dynamic regulator of leukocyte migration
Eur J Cell Biol, 91 (4), 257-64
DOI 10.1016/j.ejcb.2011.02.007, PubMed 21546114

Publications 2008

Schubert SW, Abendroth A, Kilian K, Vogler T, Mayr B, Knerr I, Hashemolhosseini S (2008)
bZIP-Type transcription factors CREB and OASIS bind and stimulate the promoter of the mammalian transcription factor GCMa/Gcm1 in trophoblast cells
Nucleic Acids Res, 36 (11), 3834-46
DOI 10.1093/nar/gkn306, PubMed 18495750

Publications 2007

Schubert SW, Lamoureux N, Kilian K, Klein-Hitpass L, Hashemolhosseini S (2007)
Identification of integrin-alpha4, Rb1, and syncytin a as murine placental target genes of the transcription factor GCMa/Gcm1
J Biol Chem, 283 (9), 5460-5
DOI 10.1074/jbc.M710110200, PubMed 18167345

Publications 2004

Hashemolhosseini S, Schmidt K, Kilian K, Rodriguez E, Wegner M (2004)
Conservation and variation of structure and function in a newly identified GCM homolog from chicken
J Mol Biol, 336 (2), 441-51
DOI 10.1016/j.jmb.2003.12.029, PubMed 14757056

Kilian K, Dernedde J, Mueller EC, Bahr I, Tauber R (2004)
The interaction of protein kinase C isozymes alpha, iota, and theta with the cytoplasmic domain of L-selectin is modulated by phosphorylation of the receptor
J Biol Chem, 279 (33), 34472-80
DOI 10.1074/jbc.M405916200, PubMed 15192100

Schubert SW, Kardash E, Khan MA, Cheusova T, Kilian K, Wegner M, Hashemolhosseini S (2004)
Interaction, cooperative promoter modulation, and renal colocalization of GCMa and Pitx2
J Biol Chem, 279 (48), 50358-65
DOI 10.1074/jbc.M404587200, PubMed 15385555

Zakowski V, Keramas G, Kilian K, Rapp UR, Ludwig S (2004)
Mitogen-activated 3p kinase is active in the nucleus
Exp Cell Res, 299 (1), 101-9
DOI 10.1016/j.yexcr.2004.05.027, PubMed 15302577

Publications 2003

Cohen SX, Moulin M, Hashemolhosseini S, Kilian K, Wegner M, Müller CW (2003)
Structure of the GCM domain-DNA complex: a DNA-binding domain with a novel fold and mode of target site recognition
EMBO J, 22 (8), 1835-45
DOI 10.1093/emboj/cdg182, PubMed 12682016

Hashemolhosseini S, Kilian K, Kardash E, Lischka P, Stamminger T, Wegner M (2003)
Structural requirements for nuclear localization of GCMa/Gcm-1
FEBS Lett, 553 (3), 315-20
DOI 10.1016/s0014-5793(03)01037-8, PubMed 14572643

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