Publications 2024

Barth C, Nerland S, Jørgensen KN, Haatveit B, Wortinger LA, Melle I, Haukvik UK, Ueland T, Andreassen OA, Agartz I (2024)
Altered Sex Differences in Hippocampal Subfield Volumes in Schizophrenia
Schizophr Bull, 50 (1), 107-119
DOI 10.1093/schbul/sbad091, PubMed 37354490

Bell C, Rokicki J, Tesli N, Gurholt TP, Hjell G, Fischer-Vieler T, Bang N, Melle I, Agartz I, Andreassen OA, Ringen PA, Rasmussen K, Dahl H, Friestad C, Haukvik UK (2024)
Hypothalamic subunit volumes and relations to violence and psychopathy in male offenders with or without a psychotic disorder
Eur Arch Psychiatry Clin Neurosci (in press)
DOI 10.1007/s00406-023-01725-4, PubMed 38353675

Berthet P, Haatveit BC, Kjelkenes R, Worker A, Kia SM, Wolfers T, Rutherford S, Alnaes D, Dinga R, Pedersen ML, Dahl A, Fernandez-Cabello S, Dazzan P, Agartz I, Nesvåg R, Ueland T, Andreassen OA, Simonsen C, Westlye LT, Melle I, Marquand A (2024)
A 10-Year Longitudinal Study of Brain Cortical Thickness in People with First-Episode Psychosis Using Normative Models
Schizophr Bull (in press)
DOI 10.1093/schbul/sbae107, PubMed 38970378

García-Marín LM, Campos AI, Diaz-Torres S, Rabinowitz JA, Ceja Z, Mitchell BL, Grasby KL, Thorp JG, Agartz I, Alhusaini S, Ames D, Amouyel P, Andreassen OA, Arfanakis K, Arias-Vasquez A, Armstrong NJ, Athanasiu L, Bastin ME, Beiser AS, Bennett DA, Bis JC, Boks MPM, Boomsma DI, Brodaty H, Brouwer RM et al. (2024)
Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries
Nat Genet, 56 (11), 2333-2344
DOI 10.1038/s41588-024-01951-z, PubMed 39433889

García-Marín LM, Campos AI, Diaz-Torres S, Rabinowitz JA, Ceja Z, Mitchell BL, Grasby KL, Thorp JG, Agartz I, Alhusaini S, Ames D, Amouyel P, Andreassen OA, Arfanakis K, Vasquez AA, Armstrong NJ, Athanasiu L, Bastin ME, Beiser AS, Bennett DA, Bis JC, Boks MP, Boomsma DI, Brodaty H, Brouwer RM et al. (2024)
Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries
medRxiv
DOI 10.1101/2024.08.13.24311922, PubMed 39371125

Giordano GM, Pezzella P, Mucci A, Austin SF, Erfurth A, Glenthøj B, Hofer A, Hubenak J, Libiger J, Melle I, Nielsen MØ, Rybakowski JK, Wojciak P, Galderisi S, Sachs G (2024)
Negative symptoms and social cognition as mediators of the relationship between neurocognition and functional outcome in schizophrenia
Front Psychiatry, 15, 1333711
DOI 10.3389/fpsyt.2024.1333711, PubMed 38356912

Johansen IT, Steen NE, Rødevand L, Lunding SH, Hjell G, Ormerod MBEG, Agartz I, Melle I, Lagerberg TV, Nerhus M, Andreassen OA (2024)
Sex differences in autonomic adverse effects related to antipsychotic treatment and associated hormone profiles
Schizophrenia (Heidelb), 10 (1), 6
DOI 10.1038/s41537-023-00430-4, PubMed 38182592

Kreis I, Lagerberg TV, Wold KF, Åsbø G, Simonsen C, Flaaten CB, Engen MJ, Lyngstad SH, Widing LH, Ueland T, Melle I (2024)
Behind the heterogeneity in the long-term course of first-episode psychosis: Different psychotic symptom trajectories are associated with different patterns of cannabis and stimulant use
Schizophr Res, 271, 91-99
DOI 10.1016/j.schres.2024.07.006, PubMed 39018985

Kreis I, Wold KF, Åsbø G, Simonsen C, Flaaten CB, Engen MJ, Lyngstad SH, Widing LH, Ueland T, Melle I (2024)
The relationship between visual hallucinations, functioning, and suicidality over the course of illness: a 10-year follow-up study in first-episode psychosis
Schizophrenia (Heidelb), 10 (1), 30
DOI 10.1038/s41537-024-00450-8, PubMed 38431677

Lunde KB, Mehlum L, Melle I, Qin P (2024)
Psychiatric follow-up and repeated hospital presentation of DSH: A national study on young adults
J Affect Disord, 368, 383-389
DOI 10.1016/j.jad.2024.09.086, PubMed 39299596

Millgate E, Smart SE, Pardiñas AF, Kravariti E, Ajnakina O, Kępińska AP, Andreassen OA, Barnes TRE, Berardi D, Crespo-Facorro B, D'Andrea G, Demjaha A, Di Forti M, Doody GA, Üçok A, Kassoumeri L, Ferchiou A, Guidi L, Joyce EM, Lastrina O, Melle I, Pignon B, Richard JR, Simonsen C, Szöke A et al. (2024)
Corrigendum to "Cognitive performance at first episode of psychosis and the relationship with future treatment resistance: Evidence from an international prospective cohort study" [Schizophr. Res. volume 225 (May 2023) 173-181]
Schizophr Res, 270, 495-496
DOI 10.1016/j.schres.2024.06.029, PubMed 39079354

Mohn C, Ueland T, Haatveit B, Sæther LS, Lagerberg TV, Andreassen OA, Melle I, Vaskinn A (2024)
Neurocognitive function and delusion severity in schizophrenia spectrum disorders
Schizophr Res, 270, 172-177
DOI 10.1016/j.schres.2024.06.028, PubMed 38917554

Pentz AB, O'Connel KS, van Jole O, Timpe CMF, Slapø NB, Melle I, Lagerberg TV, Steen NE, Westlye LT, Haukvik UK, Moberget T, Jönsson EG, Andreassen OA, Elvsåshagen T (2024)
Mismatch negativity and polygenic risk scores for schizophrenia and bipolar disorder
Schizophr Res, 264, 314-326
DOI 10.1016/j.schres.2024.01.013, PubMed 38215567

Shafi DES, Jørgensen KN, Bjella T, Nesvåg R, Dieset I, Melle I, Andreassen OA, Jönsson EG (2024)
Prescriptions of psychotropic and somatic medications among patients with severe mental disorders and healthy controls in a naturalistic study
Nord J Psychiatry, 78 (3), 212-219
DOI 10.1080/08039488.2024.2305806, PubMed 38306243

Simonsen C, Åsbø G, Slade M, Wold KF, Widing L, Flaaten CB, Engen MJ, Lyngstad SH, Gardsjord E, Bjella T, Romm KL, Ueland T, Melle I (2024)
A good life with psychosis: rate of positive outcomes in first-episode psychosis at 10-year follow-up
Psychol Med, 54 (9), 2112-2121
DOI 10.1017/S0033291724000205, PubMed 38389456

Sæther LS, Szabo A, Akkouh IA, Haatveit B, Mohn C, Vaskinn A, Aukrust P, Ormerod MBEG, Eiel Steen N, Melle I, Djurovic S, Andreassen OA, Ueland T, Ueland T (2024)
Cognitive and inflammatory heterogeneity in severe mental illness: Translating findings from blood to brain
Brain Behav Immun, 118, 287-299
DOI 10.1016/j.bbi.2024.03.014, PubMed 38461955

Sæther LS, Ueland T, Haatveit B, Vaskinn A, Bärthel Flaaten C, Mohn C, E G Ormerod MB, Aukrust P, Melle I, Steen NE, Andreassen OA, Ueland T (2024)
Longitudinal course of inflammatory-cognitive subgroups across first treatment severe mental illness and healthy controls
Psychol Med, 54 (12), 1-11 (in press)
DOI 10.1017/S003329172400206X, PubMed 39354711

Tesfaye M, Spindola LM, Stavrum AK, Shadrin A, Melle I, Andreassen OA, Le Hellard S (2024)
Sex effects on DNA methylation affect discovery in epigenome-wide association study of schizophrenia
Mol Psychiatry, 29 (8), 2467-2477
DOI 10.1038/s41380-024-02513-9, PubMed 38503926

Vaskinn A, Ueland T, Melle I, Sundet K (2024)
Sex differences in social cognition among individuals with schizophrenia and in healthy control participants: a secondary analysis of published data
Arch Womens Ment Health, 27 (5), 661-667
DOI 10.1007/s00737-024-01422-8, PubMed 38244033

Wold KF, Kreis IV, Åsbø G, Flaaten CB, Widing L, Engen MJ, Lyngstad SH, Johnsen E, Ueland T, Simonsen C, Melle I (2024)
Long-term clinical recovery and treatment resistance in first-episode psychosis: a 10-year follow-up study
Schizophrenia (Heidelb), 10 (1), 69
DOI 10.1038/s41537-024-00489-7, PubMed 39174576

Wold KF, Ottesen A, Flaaten CB, Kreis I, Lagerberg TV, Romm KL, Simonsen C, Widing L, Åsbø G, Melle I (2024)
Childhood trauma and treatment resistance in first-episode psychosis: Investigating the role of premorbid adjustment and duration of untreated psychosis
Schizophr Res, 270, 441-450
DOI 10.1016/j.schres.2024.07.001, PubMed 38991420

Åsbø G, Haavind H, Kruse SH, Wold KF, Hegelstad WTV, Romm KL, Slade M, Ueland T, Melle I, Simonsen C (2024)
Taking what you get or Getting what you Need: A Qualitative Study on Experiences with Mental Health and Welfare Services in Long-Term Recovery in First-Episode Psychosis
Community Ment Health J (in press)
DOI 10.1007/s10597-024-01356-6, PubMed 39414695

Publications 2023

Bauer M, Glenn T, Achtyes ED, Alda M, Agaoglu E, Altınbaş K, Andreassen OA, Angelopoulos E, Ardau R, Aydin M, Ayhan Y, Baethge C, Bauer R, Baune BT, Balaban C, Becerra-Palars C, Behere AP, Behere PB, Belete H, Belete T, Belizario GO, Bellivier F, Belmaker RH, Benedetti F, Berk M et al. (2023)
Exploratory study of ultraviolet B (UVB) radiation and age of onset of bipolar disorder
Int J Bipolar Disord, 11 (1), 22
DOI 10.1186/s40345-023-00303-w, PubMed 37347392

Docherty AR, Mullins N, Ashley-Koch AE, Qin X, Coleman JRI, Shabalin A, Kang J, Murnyak B, Wendt F, Adams M, Campos AI, DiBlasi E, Fullerton JM, Kranzler HR, Bakian AV, Monson ET, Rentería ME, Walss-Bass C, Andreassen OA, Behera C, Bulik CM, Edenberg HJ, Kessler RC, Mann JJ, Nurnberger JI et al. (2023)
GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors
Am J Psychiatry, 180 (10), 723-738
DOI 10.1176/appi.ajp.21121266, PubMed 37777856

Fischer-Vieler T, Ringen PA, Kvig E, Bell C, Hjell G, Tesli N, Rokicki J, Melle I, Andreassen OA, Friestad C, Haukvik UK (2023)
Associations Between Clinical Insight and History of Severe Violence in Patients With Psychosis
Schizophr Bull Open, 4 (1), sgad011
DOI 10.1093/schizbullopen/sgad011, PubMed 39145347

Flaaten CB, Melle I, Bjella T, Engen MJ, Åsbø G, Wold KF, Widing L, Gardsjord E, Øie MG, Lyngstad SH, Haatveit B, Simonsen C, Ueland T (2023)
Long-term course of cognitive functioning in bipolar disorder: A ten-year follow-up study
Bipolar Disord, 26 (2), 136-147
DOI 10.1111/bdi.13364, PubMed 37356974

Glastad SH, Aminoff SR, Hagen R, Høegh MC, Büchmann CB, Barrett EA, Melle I, Etain B, Lagerberg TV (2023)
Nicotine use and non-pathological alcohol use and their relationship to affective symptoms and sleep disturbances in bipolar disorder
J Affect Disord, 327, 236-243
DOI 10.1016/j.jad.2023.02.003, PubMed 36746243

Gohar SM, Hegelstad WTV, Auestad B, Haahr UH, Joa I, Johannessen JO, Larsen TK, Opjordsmoen S, Rund BR, Røssberg JI, Simonsen E, Friis S, Melle I (2023)
Association between early suicidal trajectories in first-episode psychosis and 10-year follow-up: TIPS registry-linked study
Lancet Psychiatry, 10 (7), 528-536
DOI 10.1016/S2215-0366(23)00156-6, PubMed 37353264

Haug E, Øie MG, Svendsen IH, Møller P, Nelson B, Melle I (2023)
A seven-year longitudinal study of the association between neurocognitive function and basic self-disorders in schizophrenia
Front Psychol, 14, 1124859
DOI 10.3389/fpsyg.2023.1124859, PubMed 36923145

Hjell G, Rokicki J, Szabo A, Holst R, Tesli N, Bell C, Fischer-Vieler T, Werner MCF, Lunding SH, Ormerod MBEG, Johansen IT, Djurovic S, Ueland T, Andreassen OA, Melle I, Lagerberg TV, Mørch-Johnsen L, Steen NE, Haukvik UK (2023)
Impulsivity across severe mental disorders: a cross-sectional study of immune markers and psychopharmacotherapy
BMC Psychiatry, 23 (1), 659
DOI 10.1186/s12888-023-05154-4, PubMed 37674162

Haatveit B, Westlye LT, Vaskinn A, Flaaten CB, Mohn C, Bjella T, Sæther LS, Sundet K, Melle I, Andreassen OA, Alnæs D, Ueland T (2023)
Intra- and inter-individual cognitive variability in schizophrenia and bipolar spectrum disorder: an investigation across multiple cognitive domains
Schizophrenia (Heidelb), 9 (1), 89
DOI 10.1038/s41537-023-00414-4, PubMed 38110366

Ihler HM, Lyngstad SH, Gardsjord ES, Widing LH, Flaaten CB, Åsbø G, Wold KF, Engen MJ, Simonsen C, Ueland T, Lagerberg TV, Melle I, Romm KL (2023)
The trajectory of two negative symptom dimensions in first-episode psychosis and the role of cannabis use: A 10-year follow-up study
Schizophr Res, 252, 317-325
DOI 10.1016/j.schres.2023.01.024, PubMed 36706477

Ihler HM, Lyngstad SH, Mørch-Johnsen LE, Lagerberg TV, Melle I, Romm KL (2023)
A transdiagnostic approach to negative symptoms: exploring factor structure and negative symptoms in bipolar disorders
Front Psychiatry, 14, 1136097
DOI 10.3389/fpsyt.2023.1136097, PubMed 37398600

Jensen SB, Sheikh MA, Akkouh IA, Szabo A, O'Connell KS, Lekva T, Engh JA, Agartz I, Elvsåshagen T, Ormerod MBEG, Weibell MA, Johnsen E, Kroken RA, Melle I, Drange OK, Nærland T, Vaaler AE, Westlye LT, Aukrust P, Djurovic S, Eiel Steen N, Andreassen OA, Ueland T (2023)
Elevated Systemic Levels of Markers Reflecting Intestinal Barrier Dysfunction and Inflammasome Activation Are Correlated in Severe Mental Illness
Schizophr Bull, 49 (3), 635-645
DOI 10.1093/schbul/sbac191, PubMed 36462169

Lunding SH, Ueland T, Aas M, Høegh MC, Werner MCF, Rødevand L, Johansen IT, Hjell G, Ormerod MBEG, Ringen PA, Ottesen A, Lagerberg TV, Melle I, Andreassen OA, Simonsen C, Steen NE (2023)
Tobacco smoking related to childhood trauma mediated by cognitive control and impulsiveness in severe mental disorders
Schizophr Res, 261, 236-244
DOI 10.1016/j.schres.2023.09.041, PubMed 37806047

Lyngstad SH, Lyne JP, Ihler HM, van der Meer L, Færden A, Melle I (2023)
Turning the Spotlight on Apathy: Identification and Treatment in Schizophrenia Spectrum Disorders
Schizophr Bull, 49 (5), 1099-1104
DOI 10.1093/schbul/sbad070, PubMed 37193675

Løchen AR, Kolskår KK, de Lange AG, Sneve MH, Haatveit B, Lagerberg TV, Ueland T, Melle I, Andreassen OA, Westlye LT, Alnæs D (2023)
Visual processing deficits in patients with schizophrenia spectrum and bipolar disorders and associations with psychotic symptoms, and intellectual abilities
Heliyon, 9 (2), e13354
DOI 10.1016/j.heliyon.2023.e13354, PubMed 36825178

Millgate E, Smart SE, Pardiñas AF, Kravariti E, Ajnakina O, Kępińska AP, Andreassen OA, Barnes TRE, Berardi D, Crespo-Facorro B, D'Andrea G, Demjaha A, Di Forti M, Doody GA, Kassoumeri L, Ferchiou A, Guidi L, Joyce EM, Lastrina O, Melle I, Pignon B, Richard JR, Simonsen C, Szöke A, Tarricone I et al. (2023)
Cognitive performance at first episode of psychosis and the relationship with future treatment resistance: Evidence from an international prospective cohort study
Schizophr Res, 255, 173-181
DOI 10.1016/j.schres.2023.03.020, PubMed 37001392

Mlakar V, Birkenæs V, Elvsaashagen T, Ormerod MBEG, Quintana DS, Ueland T, Melle I, Lagerberg TV, Djurovic S, Martin-Ruiz C, Steen NE, Andreassen OA, Aas M (2023)
Telomere length and verbal learning in bipolar disorders
J Affect Disord, 339, 555-560
DOI 10.1016/j.jad.2023.07.087, PubMed 37459977

Mørch-Johnsen L, Jørgensen KN, Barth C, Nerland S, Bringslid IK, Wortinger LA, Andreou D, Melle I, Andreassen OA, Agartz I (2023)
Thalamic nuclei volumes in schizophrenia and bipolar spectrum disorders - Associations with diagnosis and clinical characteristics
Schizophr Res, 256, 26-35
DOI 10.1016/j.schres.2023.04.008, PubMed 37126979

Pentz AB, Timpe CMF, Normann EM, Slapø NB, Melle I, Lagerberg TV, Steen NE, Westlye LT, Jönsson EG, Haukvik UK, Moberget T, Andreassen OA, Elvsåshagen T (2023)
Mismatch negativity in schizophrenia spectrum and bipolar disorders: Group and sex differences and associations with symptom severity
Schizophr Res, 261, 80-93
DOI 10.1016/j.schres.2023.09.012, PubMed 37716205

Seljenes Bøe A, Mehlum L, Melle I, Qin P (2023)
Psychiatric disorders among adult deliberate self-harm patients and subsequent risk of dying by suicide, mental and behavioural disorders and other external causes
J Psychiatr Res, 165, 83-90
DOI 10.1016/j.jpsychires.2023.07.011, PubMed 37481790

Slapø NB, Jørgensen KN, Elvsåshagen T, Nerland S, Roelfs D, Valstad M, Timpe CMF, Richard G, Beck D, Sæther LS, Frogner Werner MC, Lagerberg TV, Andreassen OA, Melle I, Agartz I, Westlye LT, Moberget T, Jönsson EG (2023)
Relationship between function and structure in the visual cortex in healthy individuals and in patients with severe mental disorders
Psychiatry Res Neuroimaging, 332, 111633
DOI 10.1016/j.pscychresns.2023.111633, PubMed 37028226

Slapø NB, Nerland S, Nordbø Jørgensen K, Mørch-Johnsen L, Pettersen JH, Roelfs D, Parker N, Valstad M, Pentz A, Timpe CMF, Richard G, Beck D, Werner MCF, Lagerberg TV, Melle I, Agartz I, Westlye LT, Steen NE, Andreassen OA, Moberget T, Elvsåshagen T, Jönsson EG (2023)
Auditory Cortex Thickness Is Associated With N100 Amplitude in Schizophrenia Spectrum Disorders
Schizophr Bull Open, 4 (1), sgad015
DOI 10.1093/schizbullopen/sgad015, PubMed 38812720

Torsvik A, Brattbakk HR, Trentani A, Holdhus R, Stansberg C, Bartz-Johannessen CA, Hughes T, Steen NE, Melle I, Djurovic S, Andreassen OA, Steen VM (2023)
Patients with schizophrenia and bipolar disorder display a similar global gene expression signature in whole blood that reflects elevated proportion of immature neutrophil cells with association to lipid changes
Transl Psychiatry, 13 (1), 147
DOI 10.1038/s41398-023-02442-1, PubMed 37147304

Widing L, Simonsen C, Bjella T, Engen MJ, Flaaten CB, Gardsjord E, Haatveit B, Haug E, Lyngstad SH, Svendsen IH, Vik RK, Wold KF, Åsbø G, Ueland T, Melle I (2023)
Long-term Outcomes of People With DSM Psychotic Disorder NOS
Schizophr Bull Open, 4 (1), sgad005
DOI 10.1093/schizbullopen/sgad005, PubMed 39145337

Wold KF, Ottesen A, Camilla BF, Johnsen E, Lagerberg TV, Romm KL, Simonsen C, Ueland T, Widing L, Åsbø G, Melle I (2023)
Early identification of treatment non-response in first-episode psychosis
Eur Psychiatry, 66 (1), e30
DOI 10.1192/j.eurpsy.2023.15, PubMed 36915260

Publications 2022

Aminoff SR, Mork E, Barrett EA, Simonsen C, Ten Velden Hegelstad W, Lagerberg TV, Melle I, Romm KL (2022)
Locked out during COVID-19 lockdown-an online survey of relatives of people with psychotic and bipolar disorders in Norway
BMC Public Health, 22 (1), 294
DOI 10.1186/s12889-022-12625-y, PubMed 35151293

Aminoff SR, Onyeka IN, Ødegaard M, Simonsen C, Lagerberg TV, Andreassen OA, Romm KL, Melle I (2022)
Lifetime and point prevalence of psychotic symptoms in adults with bipolar disorders: a systematic review and meta-analysis
Psychol Med, 52 (13), 2413-2425
DOI 10.1017/S003329172200201X, PubMed 36016504

Barrett EA, Simonsen C, Aminoff SR, Hegelstad WTV, Lagerberg TV, Melle I, Mork E, Romm KL (2022)
The COVID-19 pandemic impact on wellbeing and mental health in people with psychotic and bipolar disorders
Brain Behav, 12 (5), e2559
DOI 10.1002/brb3.2559, PubMed 35385888

Bauer M, Glenn T, Achtyes ED, Alda M, Agaoglu E, Altınbaş K, Andreassen OA, Angelopoulos E, Ardau R, Aydin M, Ayhan Y, Baethge C, Bauer R, Baune BT, Balaban C, Becerra-Palars C, Behere AP, Behere PB, Belete H, Belete T, Belizario GO, Bellivier F, Belmaker RH, Benedetti F, Berk M et al. (2022)
Association between polarity of first episode and solar insolation in bipolar I disorder
J Psychosom Res, 160, 110982
DOI 10.1016/j.jpsychores.2022.110982, PubMed 35932492

Bell C, Tesli N, Gurholt TP, Rokicki J, Hjell G, Fischer-Vieler T, Melle I, Agartz I, Andreassen OA, Ringen PA, Rasmussen K, Dahl H, Friestad C, Haukvik UK (2022)
Psychopathy subdomains in violent offenders with and without a psychotic disorder
Nord J Psychiatry, 77 (4), 393-402
DOI 10.1080/08039488.2022.2128869, PubMed 36260740

Bjella TD, Collier Høegh M, Holmstul Olsen S, Aminoff SR, Barrett E, Ueland T, Icick R, Andreassen OA, Nerhus M, Myhre Ihler H, Hagen M, Busch-Christensen C, Melle I, Lagerberg TV (2022)
Developing "MinDag" - an app to capture symptom variation and illness mechanisms in bipolar disorder
Front Med Technol, 4, 910533
DOI 10.3389/fmedt.2022.910533, PubMed 35935144

Bøe AS, Mehlum L, Melle I, Qin P (2022)
Psychiatric disorders among adults treated for deliberate self-harm in general hospital: A national register study
J Affect Disord, 319, 490-496
DOI 10.1016/j.jad.2022.09.066, PubMed 36162670

Bøe AS, Mehlum L, Melle I, Qin P (2022)
Clinical determinants of hospital treated deliberate self-harm repetition: A time to recurrent event analysis
Acta Psychiatr Scand, 146 (6), 557-567
DOI 10.1111/acps.13503, PubMed 36177728

Dollfus S, Mucci A, Giordano GM, Bitter I, Austin SF, Delouche C, Erfurth A, Fleischhacker WW, Movina L, Glenthøj B, Gütter K, Hofer A, Hubenak J, Kaiser S, Libiger J, Melle I, Nielsen MØ, Papsuev O, Rybakowski JK, Sachs G, Üçok A, Brando F, Wojciak P, Galderisi S (2022)
European Validation of the Self-Evaluation of Negative Symptoms (SNS): A Large Multinational and Multicenter Study
Front Psychiatry, 13, 826465
DOI 10.3389/fpsyt.2022.826465, PubMed 35173641

Elkjaer Greenwood Ormerod MB, Ueland T, Frogner Werner MC, Hjell G, Rødevand L, Sæther LS, Lunding SH, Johansen IT, Ueland T, Lagerberg TV, Melle I, Djurovic S, Andreassen OA, Steen NE (2022)
Composite immune marker scores associated with severe mental disorders and illness course
Brain Behav Immun Health, 24, 100483
DOI 10.1016/j.bbih.2022.100483, PubMed 35856063

Engen MJ, Vaskinn A, Melle I, Færden A, Lyngstad SH, Flaaten CB, Widing LH, Wold KF, Åsbø G, Haatveit B, Simonsen C, Ueland T (2022)
Cognitive and Global Functioning in Patients With First-Episode Psychosis Stratified by Level of Negative Symptoms. A 10-Year Follow-Up Study
Front Psychiatry, 13, 841057
DOI 10.3389/fpsyt.2022.841057, PubMed 35401286

Engh JA, Ueland T, Agartz I, Andreou D, Aukrust P, Boye B, Bøen E, Drange OK, Elvsåshagen T, Hope S, Høegh MC, Joa I, Johnsen E, Kroken RA, Lagerberg TV, Lekva T, Malt UF, Melle I, Morken G, Nærland T, Steen VM, Wedervang-Resell K, Weibell MA, Westlye LT, Djurovic S et al. (2022)
Plasma Levels of the Cytokines B Cell-Activating Factor (BAFF) and A Proliferation-Inducing Ligand (APRIL) in Schizophrenia, Bipolar, and Major Depressive Disorder: A Cross Sectional, Multisite Study
Schizophr Bull, 48 (1), 37-46
DOI 10.1093/schbul/sbab106, PubMed 34499169

Flaaten CB, Melle I, Bjella T, Engen MJ, Åsbø G, Wold KF, Widing L, Gardsjord E, Sæther LS, Øie MG, Lyngstad SH, Haatveit B, Simonsen C, Ueland T (2022)
Domain-specific cognitive course in schizophrenia: Group- and individual-level changes over 10 years
Schizophr Res Cogn, 30, 100263
DOI 10.1016/j.scog.2022.100263, PubMed 35783460

Flaaten CB, Melle I, Gardsjord E, Bjella T, Engen MJ, Vaskinn A, Åsbø G, Wold KF, Widing L, Lyngstad SH, Haatveit B, Simonsen C, Ueland T (2022)
Course of intellectual functioning in schizophrenia and bipolar disorder: a 10-year follow-up study
Psychol Med, 53 (6), 2662-2670
DOI 10.1017/S0033291721004645, PubMed 35256030

Gjerde PB, Steen SW, Vedal TSJ, Steen NE, Reponen EJ, Andreassen OA, Steen VM, Melle I (2022)
Lifetime Cannabis Use Is Not Associated With Negative Beliefs About Medication in Patients With First Treatment Psychosis
Front Psychiatry, 13, 824051
DOI 10.3389/fpsyt.2022.824051, PubMed 35422717

Hjell G, Szabo A, Mørch-Johnsen L, Holst R, Tesli N, Bell C, Fischer-Vieler T, Werner MCF, Lunding SH, Ormerod MBEG, Johansen IT, Dieset I, Djurovic S, Melle I, Ueland T, Andreassen OA, Steen NE, Haukvik UK (2022)
Interleukin-18 signaling system links to agitation in severe mental disorders
Psychoneuroendocrinology, 140, 105721
DOI 10.1016/j.psyneuen.2022.105721, PubMed 35301151

Høegh MC, Melle I, Aminoff SR, Olsen SH, Lunding SH, Ueland T, Lagerberg TV (2022)
Affective lability and social functioning in severe mental disorders
Eur Arch Psychiatry Clin Neurosci, 272 (5), 873-885
DOI 10.1007/s00406-022-01380-1, PubMed 35084540

Icick R, Melle I, Etain B, Høegh MC, Gard S, Aminoff SR, Leboyer M, Andreassen OA, Belzeaux R, Henry C, Bjella TD, Kahn JP, Steen NE, Bellivier F, Lagerberg TV (2022)
Preventive Medication Patterns in Bipolar Disorder and Their Relationship With Comorbid Substance Use Disorders in a Cross-National Observational Study
Front Psychiatry, 13, 813256
DOI 10.3389/fpsyt.2022.813256, PubMed 35592382

Johansen IT, Steen NE, Haram M, Rødevand L, Werner MCF, Lunding SH, Hjell G, Agartz I, Melle I, Lagerberg TV, Nerhus M, Andreassen OA (2022)
Sex differences in antipsychotic-related triglyceride levels are associated with metabolic hormone differences in patients with severe mental disorders
Schizophr Res, 243, 55-63
DOI 10.1016/j.schres.2022.02.015, PubMed 35240428

Johansen IT, Steen NE, Rødevand L, Werner MCF, Lunding SH, Hjell G, Ormerod MBEG, Agartz I, Melle I, Lagerberg TV, Nerhus M, Andreassen OA (2022)
Sex-specific associations between metabolic hormones, severe mental disorders and antipsychotic treatment
Psychoneuroendocrinology, 146, 105927
DOI 10.1016/j.psyneuen.2022.105927, PubMed 36152455

Lunde KB, Mehlum L, Melle I, Qin P (2022)
Psychiatric admissions after hospital presented deliberate self-harm in the young: A national study
J Psychiatr Res, 151, 575-582
DOI 10.1016/j.jpsychires.2022.05.020, PubMed 35636035

Løkhammer S, Stavrum AK, Polushina T, Aas M, Ottesen AA, Andreassen OA, Melle I, Le Hellard S (2022)
An epigenetic association analysis of childhood trauma in psychosis reveals possible overlap with methylation changes associated with PTSD
Transl Psychiatry, 12 (1), 177
DOI 10.1038/s41398-022-01936-8, PubMed 35501310

Mork E, Aminoff SR, Barrett EA, Simonsen C, Hegelstad WTV, Lagerberg TV, Melle I, Romm KL (2022)
COVID-19 lockdown - who cares? The first lockdown from the perspective of relatives of people with severe mental illness
BMC Public Health, 22 (1), 1104
DOI 10.1186/s12889-022-13458-5, PubMed 35655294

Pardiñas AF, Smart SE, Willcocks IR, Holmans PA, Dennison CA, Lynham AJ, Legge SE, Baune BT, Bigdeli TB, Cairns MJ, Corvin A, Fanous AH, Frank J, Kelly B, McQuillin A, Melle I, Mortensen PB, Mowry BJ, Pato CN, Periyasamy S, Rietschel M, Rujescu D, Simonsen C, St Clair D, Tooney P et al. (2022)
Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia
JAMA Psychiatry, 79 (3), 260-269
DOI 10.1001/jamapsychiatry.2021.3799, PubMed 35019943

Qin P, Stanley B, Melle I, Mehlum L (2022)
Association of Psychiatric Services Referral and Attendance Following Treatment for Deliberate Self-harm With Prospective Mortality in Norwegian Patients
JAMA Psychiatry, 79 (7), 651-658
DOI 10.1001/jamapsychiatry.2022.1124, PubMed 35583901

Sahl AC, Rognlien HF, Andreassen OA, Melle I, Ueland T, Vaskinn A (2022)
Theory of mind in schizophrenia: a comparison of subgroups with low and high IQ
Nord J Psychiatry, 77 (4), 329-335
DOI 10.1080/08039488.2022.2106512, PubMed 35916656

Sheikh MA, O'Connell KS, Lekva T, Szabo A, Akkouh IA, Osete JR, Agartz I, Engh JA, Andreou D, Boye B, Bøen E, Elvsåshagen T, Hope S, Frogner Werner MC, Joa I, Johnsen E, Kroken RA, Lagerberg TV, Melle I, Drange OK, Morken G, Nærland T, Sørensen K, Vaaler AE, Weibell MA et al. (2022)
Systemic Cell Adhesion Molecules in Severe Mental Illness: Potential Role of Intercellular CAM-1 in Linking Peripheral and Neuroinflammation
Biol Psychiatry, 93 (2), 187-196
DOI 10.1016/j.biopsych.2022.06.029, PubMed 36182530

Smart SE, Agbedjro D, Pardiñas AF, Ajnakina O, Alameda L, Andreassen OA, Barnes TRE, Berardi D, Camporesi S, Cleusix M, Conus P, Crespo-Facorro B, D'Andrea G, Demjaha A, Di Forti M, Do K, Doody G, Eap CB, Ferchiou A, Guidi L, Homman L, Jenni R, Joyce E, Kassoumeri L, Lastrina O et al. (2022)
Clinical predictors of antipsychotic treatment resistance: Development and internal validation of a prognostic prediction model by the STRATA-G consortium
Schizophr Res, 250, 1-9
DOI 10.1016/j.schres.2022.09.009, PubMed 36242784

Sæther LS, Ueland T, Haatveit B, Maglanoc LA, Szabo A, Djurovic S, Aukrust P, Roelfs D, Mohn C, Ormerod MBEG, Lagerberg TV, Steen NE, Melle I, Andreassen OA, Ueland T (2022)
Inflammation and cognition in severe mental illness: patterns of covariation and subgroups
Mol Psychiatry, 28 (3), 1284-1292
DOI 10.1038/s41380-022-01924-w, PubMed 36577840

Tesli N, Bell C, Hjell G, Fischer-Vieler T, I Maximov I, Richard G, Tesli M, Melle I, Andreassen OA, Agartz I, Westlye LT, Friestad C, Haukvik UK, Rokicki J (2022)
The age of violence: Mapping brain age in psychosis and psychopathy
Neuroimage Clin, 36, 103181
DOI 10.1016/j.nicl.2022.103181, PubMed 36088844

Trubetskoy V, Pardiñas AF, Qi T, Panagiotaropoulou G, Awasthi S, Bigdeli TB, Bryois J, Chen CY, Dennison CA, Hall LS, Lam M, Watanabe K, Frei O, Ge T, Harwood JC, Koopmans F, Magnusson S, Richards AL, Sidorenko J, Wu Y, Zeng J, Grove J, Kim M, Li Z, Voloudakis G et al. (2022)
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Nature, 604 (7906), 502-508
DOI 10.1038/s41586-022-04434-5, PubMed 35396580

van der Meer D, Shadrin AA, O'Connell K, Bettella F, Djurovic S, Wolfers T, Alnæs D, Agartz I, Smeland OB, Melle I, Sánchez JM, Linden DEJ, Dale AM, Westlye LT, Andreassen OA, Frei O, Kaufmann T (2022)
Boosting Schizophrenia Genetics by Utilizing Genetic Overlap With Brain Morphology
Biol Psychiatry, 92 (4), 291-298
DOI 10.1016/j.biopsych.2021.12.007, PubMed 35164939

Werner MCF, Wirgenes KV, Shadrin A, Lunding SH, Rødevand L, Hjell G, Ormerod MBEG, Haram M, Agartz I, Djurovic S, Melle I, Aukrust P, Ueland T, Andreassen OA, Steen NE (2022)
Immune marker levels in severe mental disorders: associations with polygenic risk scores of related mental phenotypes and psoriasis
Transl Psychiatry, 12 (1), 38
DOI 10.1038/s41398-022-01811-6, PubMed 35082268

Werner MCF, Wirgenes KV, Shadrin AA, Lunding SH, Rødevand L, Hjell G, Ormerod MBEG, Haram M, Agartz I, Djurovic S, Melle I, Aukrust P, Ueland T, Andreassen OA, Steen NE (2022)
Limited association between infections, autoimmune disease and genetic risk and immune activation in severe mental disorders
Prog Neuropsychopharmacol Biol Psychiatry, 116, 110511
DOI 10.1016/j.pnpbp.2022.110511, PubMed 35063598

Widing L, Simonsen C, Flaaten CB, Haatveit B, Vik RK, Wold KF, Åsbø G, Ueland T, Melle I (2022)
Premorbid characteristics of patients with DSM-IV psychotic disorders
Compr Psychiatry, 115, 152310
DOI 10.1016/j.comppsych.2022.152310, PubMed 35385814

Aas M, Ueland T, Lagerberg TV, Melle I, Aminoff SR, Hoegh MC, Lunding SH, Laskemoen JF, Steen NE, Andreassen OA (2022)
Retrospectively assessed childhood trauma experiences are associated with illness severity in mental disorders adjusted for symptom state
Psychiatry Res, 320, 115045
DOI 10.1016/j.psychres.2022.115045, PubMed 36621206

Åsbø G, Ueland T, Haatveit B, Bjella T, Flaaten CB, Wold KF, Widing L, Engen MJ, Lyngstad SH, Gardsjord E, Romm KL, Melle I, Simonsen C (2022)
The Time is Ripe for a Consensus Definition of Clinical Recovery in First-episode Psychosis: Suggestions Based on a 10-Year Follow-up Study
Schizophr Bull, 48 (4), 839-849
DOI 10.1093/schbul/sbac035, PubMed 35419608

Publications 2021

Abé C, Ching CRK, Liberg B, Lebedev AV, Agartz I, Akudjedu TN, Alda M, Alnæs D, Alonso-Lana S, Benedetti F, Berk M, Bøen E, Bonnin CDM, Breuer F, Brosch K, Brouwer RM, Canales-Rodríguez EJ, Cannon DM, Chye Y, Dahl A, Dandash O, Dannlowski U, Dohm K, Elvsåshagen T, Fisch L et al. (2021)
Longitudinal Structural Brain Changes in Bipolar Disorder: A Multicenter Neuroimaging Study of 1232 Individuals by the ENIGMA Bipolar Disorder Working Group
Biol Psychiatry, 91 (6), 582-592
DOI 10.1016/j.biopsych.2021.09.008, PubMed 34809987

Bauer M, Glenn T, Achtyes ED, Alda M, Agaoglu E, Altınbaş K, Andreassen OA, Angelopoulos E, Ardau R, Vares EA, Aydin M, Ayhan Y, Baethge C, Bauer R, Baune BT, Balaban C, Becerra-Palars C, Behere AP, Behere PB, Belete H, Belete T, Belizario GO, Bellivier F, Belmaker RH, Benedetti F et al. (2021)
Variations in seasonal solar insolation are associated with a history of suicide attempts in bipolar I disorder
Int J Bipolar Disord, 9 (1), 26
DOI 10.1186/s40345-021-00231-7, PubMed 34467430

Bell C, Tesli N, Gurholt TP, Rokicki J, Hjell G, Fischer-Vieler T, Melle I, Agartz I, Andreassen OA, Rasmussen K, Johansen R, Friestad C, Haukvik UK (2021)
Associations between amygdala nuclei volumes, psychosis, psychopathy, and violent offending
Psychiatry Res Neuroimaging, 319, 111416
DOI 10.1016/j.pscychresns.2021.111416, PubMed 34847406

Blokland GAM, Grove J, Chen CY, Cotsapas C, Tobet S, Handa R, Schizophrenia Working Group of the Psychiatric Genomics Consortium, St Clair D, Lencz T, Mowry BJ, Periyasamy S, Cairns MJ, Tooney PA, Wu JQ, Kelly B, Kirov G, Sullivan PF, Corvin A, Riley BP, Esko T, Milani L, Jönsson EG, Palotie A, Ehrenreich H, Begemann M et al. (2021)
Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders
Biol Psychiatry, 91 (1), 102-117
DOI 10.1016/j.biopsych.2021.02.972, PubMed 34099189

Gjerde PB, Simonsen CE, Lagerberg TV, Steen NE, Andreassen OA, Steen VM, Melle I (2021)
Sex-Specific Effect of Serum Lipids and Body Mass Index on Psychotic Symptoms, a Cross-Sectional Study of First-Episode Psychosis Patients
Front Psychiatry, 12, 723158
DOI 10.3389/fpsyt.2021.723158, PubMed 34744818

Hegelstad WTV, Berg AO, Bjornestad J, Gismervik K, Johannessen JO, Melle I, Stain HJ, Joa I (2021)
Childhood interpersonal trauma and premorbid social adjustment as predictors of symptom remission in first episode psychosis
Schizophr Res, 232, 87-94
DOI 10.1016/j.schres.2021.05.015, PubMed 34029946

Høegh MC, Melle I, Aminoff SR, Haatveit B, Olsen SH, Huflåtten IB, Ueland T, Lagerberg TV (2021)
Characterization of affective lability across subgroups of psychosis spectrum disorders
Int J Bipolar Disord, 9 (1), 34
DOI 10.1186/s40345-021-00238-0, PubMed 34734342

Ihler HM, Lagerberg TV, Lyngstad SH, Melle I, Romm KL (2021)
Exploring the relationship between recency and frequency of cannabis use and diminished expression and apathy as two dimensions of negative symptoms in first episode psychosis. A one-year follow-up study
Schizophr Res, 236, 89-96
DOI 10.1016/j.schres.2021.08.004, PubMed 34454305

Kalman JL, Olde Loohuis LM, Vreeker A, McQuillin A, Stahl EA, Ruderfer D, Grigoroiu-Serbanescu M, Panagiotaropoulou G, Ripke S, Bigdeli TB, Stein F, Meller T, Meinert S, Pelin H, Streit F, Papiol S, Adams MJ, Adolfsson R, Adorjan K, Agartz I, Aminoff SR, Anderson-Schmidt H, Andreassen OA, Ardau R, Aubry JM et al. (2021)
Characterisation of age and polarity at onset in bipolar disorder
Br J Psychiatry, 219 (6), 659-669
DOI 10.1192/bjp.2021.102, PubMed 35048876

Lagerberg TV, Icick R, Aminoff SR, Nerhus M, Barrett EA, Bjella TD, Olsen SH, Høegh MC, Melle I (2021)
Substance Misuse Trajectories and Risk of Relapse in the Early Course of Bipolar Disorder
Front Psychiatry, 12, 656912
DOI 10.3389/fpsyt.2021.656912, PubMed 34017275

Lam M, Chen CY, Ge T, Xia Y, Hill DW, Trampush JW, Yu J, Knowles E, Davies G, Stahl EA, Huckins L, Liewald DC, Djurovic S, Melle I, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, Räikkönen K, Widen E, Palotie A, Eriksson JG, Giegling I et al. (2021)
Identifying nootropic drug targets via large-scale cognitive GWAS and transcriptomics
Neuropsychopharmacology, 46 (10), 1788-1801
DOI 10.1038/s41386-021-01023-4, PubMed 34035472

Lunding SH, Simonsen C, Aas M, Rødevand L, Werner MCF, Laskemoen JF, Hjell G, Ringen PA, Lagerberg TV, Melle I, Andreassen OA, Ueland T, Steen NE (2021)
Childhood trauma and cardiometabolic risk in severe mental disorders: The mediating role of cognitive control
Eur Psychiatry, 64 (1), e24
DOI 10.1192/j.eurpsy.2021.14, PubMed 33775258

Mullins N, Forstner AJ, O'Connell KS, Coombes B, Coleman JRI, Qiao Z, Als TD, Bigdeli TB, Børte S, Bryois J, Charney AW, Drange OK, Gandal MJ, Hagenaars SP, Ikeda M, Kamitaki N, Kim M, Krebs K, Panagiotaropoulou G, Schilder BM, Sloofman LG, Steinberg S, Trubetskoy V, Winsvold BS, Won HH et al. (2021)
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
Nat Genet, 53 (6), 817-829
DOI 10.1038/s41588-021-00857-4, PubMed 34002096

Mullins N, Kang J, Campos AI, Coleman JRI, Edwards AC, Galfalvy H, Levey DF, Lori A, Shabalin A, Starnawska A, Su MH, Watson HJ, Adams M, Awasthi S, Gandal M, Hafferty JD, Hishimoto A, Kim M, Okazaki S, Otsuka I, Ripke S, Ware EB, Bergen AW, Berrettini WH, Bohus M et al. (2021)
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
Biol Psychiatry, 91 (3), 313-327
DOI 10.1016/j.biopsych.2021.05.029, PubMed 34861974

Ottesen A, T V Hegelstad W, Joa I, Opjordsmoen SE, Rund BR, Røssberg JI, Simonsen E, Johannessen JO, Larsen TK, Haahr UH, McGlashan TH, Friis S, Melle I (2021)
Childhood trauma, antipsychotic medication, and symptom remission in first-episode psychosis
Psychol Med, 53 (6), 2399-2408
DOI 10.1017/S003329172100427X, PubMed 37144963

Szabo A, O'Connell KS, Ueland T, Sheikh MA, Agartz I, Andreou D, Aukrust P, Boye B, Bøen E, Drange OK, Elvsåshagen T, Engh JA, Hope S, Collier Høegh M, Joa I, Johnsen E, Kroken RA, Vik Lagerberg T, Lekva T, Malt UF, Melle I, Morken G, Nærland T, Steen VM, Sørensen K et al. (2021)
Increased circulating IL-18 levels in severe mental disorders indicate systemic inflammasome activation
Brain Behav Immun, 99, 299-306
DOI 10.1016/j.bbi.2021.10.017, PubMed 34758379

Takizawa N, Melle I, Barrett EA, Nerhus M, Ottesen AA (2021)
The Influence of Mental Health Literacy, Migration, and Education on the Duration of Untreated Psychosis
Front Public Health, 9, 705397
DOI 10.3389/fpubh.2021.705397, PubMed 34368068

Valstad M, Roelfs D, Slapø NB, Timpe CMF, Rai A, Matziorinis AM, Beck D, Richard G, Sæther LS, Haatveit B, Nordvik JE, Hatlestad-Hall C, Einevoll GT, Mäki-Marttunen T, Haram M, Ueland T, Lagerberg TV, Steen NE, Melle I, Westlye LT, Jönsson EG, Andreassen OA, Moberget T, Elvsåshagen T (2021)
Evidence for Reduced Long-Term Potentiation-Like Visual Cortical Plasticity in Schizophrenia and Bipolar Disorder
Schizophr Bull, 47 (6), 1751-1760
DOI 10.1093/schbul/sbab049, PubMed 33963856

Vaskinn A, Sundet K, Melle I, Andreassen OA, Friis S (2021)
The factor structure of social cognition in schizophrenia: Weak evidence for separable domains
Schizophr Res Cogn, 26, 100208
DOI 10.1016/j.scog.2021.100208, PubMed 34430229

Værnes TG, Røssberg JI, Melle I, Nelson B, Romm KL, Møller P (2021)
Basic self-disturbance in subjects at clinical high risk for psychosis: Relationship with clinical and functional outcomes at one year follow-up
Psychiatry Res, 300, 113942
DOI 10.1016/j.psychres.2021.113942, PubMed 33940444

Værnes TG, Røssberg JI, Melle I, Nelson B, Romm KL, Møller P (2021)
Basic self-disturbance trajectories in clinical high risk for psychosis: a one-year follow-up study
Eur Arch Psychiatry Clin Neurosci, 272 (6), 1007-1019
DOI 10.1007/s00406-021-01349-6, PubMed 34783878

Wolfers T, Rokicki J, Alnaes D, Berthet P, Agartz I, Kia SM, Kaufmann T, Zabihi M, Moberget T, Melle I, Beckmann CF, Andreassen OA, Marquand AF, Westlye LT (2021)
Replicating extensive brain structural heterogeneity in individuals with schizophrenia and bipolar disorder
Hum Brain Mapp, 42 (8), 2546-2555
DOI 10.1002/hbm.25386, PubMed 33638594

Aas M, Ueland T, Mørch RH, Laskemoen JF, Lunding SH, Reponen EJ, Cattaneo A, Agartz I, Melle I, Steen NE, Andreassen OA (2021)
Physical activity and childhood trauma experiences in patients with schizophrenia or bipolar disorders
World J Biol Psychiatry, 22 (8), 637-645
DOI 10.1080/15622975.2021.1907707, PubMed 33779484

Publications 2020

Elvsåshagen T, Bahrami S, van der Meer D, Agartz I, Alnæs D, Barch DM, Baur-Streubel R, Bertolino A, Beyer MK, Blasi G, Borgwardt S, Boye B, Buitelaar J, Bøen E, Celius EG, Cervenka S, Conzelmann A, Coynel D, Di Carlo P, Djurovic S, Eisenacher S, Espeseth T, Fatouros-Bergman H, Flyckt L, Franke B et al. (2020)
The genetic architecture of human brainstem structures and their involvement in common brain disorders
Nat Commun, 11 (1), 4016
DOI 10.1038/s41467-020-17376-1, PubMed 32782260

Engen MJ, Lyngstad SH, Ueland T, Simonsen CE, Vaskinn A, Smeland O, Bettella F, Lagerberg TV, Djurovic S, Andreassen OA, Melle I (2020)
Polygenic scores for schizophrenia and general cognitive ability: associations with six cognitive domains, premorbid intelligence, and cognitive composite score in individuals with a psychotic disorder and in healthy controls
Transl Psychiatry, 10 (1), 416
DOI 10.1038/s41398-020-01094-9, PubMed 33257657

Feyer FK, Andersson S, Büchmann CB, Melle I, Andreassen OA, Vaskinn A (2020)
Social Perception Predicts Awareness of Illness in Persons With Schizophrenia
J Nerv Ment Dis, 208 (9), 701-705
DOI 10.1097/NMD.0000000000001185, PubMed 32433201

Grasby KL, Jahanshad N, Painter JN, Colodro-Conde L, Bralten J, Hibar DP, Lind PA, Pizzagalli F, Ching CRK, McMahon MAB, Shatokhina N, Zsembik LCP, Thomopoulos SI, Zhu AH, Strike LT, Agartz I, Alhusaini S, Almeida MAA, Alnæs D, Amlien IK, Andersson M, Ard T, Armstrong NJ, Ashley-Koch A, Atkins JR et al. (2020)
The genetic architecture of the human cerebral cortex
Science, 367 (6484)
DOI 10.1126/science.aay6690, PubMed 32193296

Haukvik UK, Gurholt TP, Nerland S, Elvsåshagen T, Akudjedu TN, Alda M, Alnaes D, Alonso-Lana S, Bauer J, Baune BT, Benedetti F, Berk M, Bettella F, Bøen E, Bonnín CM, Brambilla P, Canales-Rodríguez EJ, Cannon DM, Caseras X, Dandash O, Dannlowski U, Delvecchio G, Díaz-Zuluaga AM, van Erp TGM, Fatjó-Vilas M et al. (2020)
In vivo hippocampal subfield volumes in bipolar disorder-A mega-analysis from The Enhancing Neuro Imaging Genetics through Meta-Analysis Bipolar Disorder Working Group
Hum Brain Mapp, 43 (1), 385-398
DOI 10.1002/hbm.25249, PubMed 33073925

Hjell G, Mørch-Johnsen L, Holst R, Tesli N, Bell C, Lunding SH, Rødevand L, Werner MCF, Melle I, Andreassen OA, Lagerberg TV, Steen NE, Haukvik UK (2020)
Disentangling the relationship between cholesterol, aggression, and impulsivity in severe mental disorders
Brain Behav, 10 (9), e01751
DOI 10.1002/brb3.1751, PubMed 32681586

Høegh MC, Melle I, Aminoff SR, Laskemoen JF, Büchmann CB, Ueland T, Lagerberg TV (2020)
Affective lability across psychosis spectrum disorders
Eur Psychiatry, 63 (1), e53
DOI 10.1192/j.eurpsy.2020.44, PubMed 32372737

Haatveit B, Mørch-Johnsen L, Alnæs D, Engen MJ, Lyngstad SH, Færden A, Agartz I, Ueland T, Melle I (2020)
Divergent relationship between brain structure and cognitive functioning in patients with prominent negative symptomatology
Psychiatry Res Neuroimaging, 307, 111233
DOI 10.1016/j.pscychresns.2020.111233, PubMed 33340940

Ihler HM, Meyrel M, Hennion V, Maruani J, Gross G, Geoffroy PA, Lagerberg TV, Melle I, Bellivier F, Scott J, Etain B (2020)
Misperception of sleep in bipolar disorder: an exploratory study using questionnaire versus actigraphy
Int J Bipolar Disord, 8 (1), 34
DOI 10.1186/s40345-020-00198-x, PubMed 33215273

Kaufmann T, van der Meer D, Doan NT, Schwarz E, Lund MJ, Agartz I, Alnæs D, Barch DM, Baur-Streubel R, Bertolino A, Bettella F, Beyer MK, Bøen E, Borgwardt S, Brandt CL, Buitelaar J, Celius EG, Cervenka S, Conzelmann A, Córdova-Palomera A, Dale AM, de Quervain DJF, Di Carlo P, Djurovic S, Dørum ES et al. (2020)
Publisher Correction: Common brain disorders are associated with heritable patterns of apparent aging of the brain
Nat Neurosci, 23 (2), 295
DOI 10.1038/s41593-019-0553-6, PubMed 31848485

Laskemoen JF, Aas M, Vaskinn A, Berg AO, Lunding SH, Barrett EA, Melle I, Simonsen C (2020)
Sleep disturbance mediates the link between childhood trauma and clinical outcome in severe mental disorders
Psychol Med, 51 (14), 2337-2346
DOI 10.1017/S0033291720000914, PubMed 32321600

Lunde KB, Mehlum L, Melle I, Qin P (2020)
Deliberate self-harm and associated risk factors in young adults: the importance of education attainment and sick leave
Soc Psychiatry Psychiatr Epidemiol, 56 (1), 153-164
DOI 10.1007/s00127-020-01893-x, PubMed 32556378

Lyngstad SH, Bettella F, Aminoff SR, Athanasiu L, Andreassen OA, Faerden A, Melle I (2020)
Associations between schizophrenia polygenic risk and apathy in schizophrenia spectrum disorders and healthy controls
Acta Psychiatr Scand, 141 (5), 452-464
DOI 10.1111/acps.13167, PubMed 32091622

Lyngstad SH, Gardsjord ES, Engen MJ, Haatveit B, Ihler HM, Wedervang-Resell K, Simonsen C, Melle I, Færden A (2020)
Trajectory and early predictors of apathy development in first-episode psychosis and healthy controls: a 10-year follow-up study
Eur Arch Psychiatry Clin Neurosci, 270 (6), 709-722
DOI 10.1007/s00406-020-01112-3, PubMed 32130475

Mehlum L, Walby F, Johannessen JO, Melle I, Andreassen O (2020)
[Strong statements – weak basis]
Tidsskr Nor Laegeforen, 140 (14)
DOI 10.4045/tidsskr.20.0744, PubMed 33070600

Mehlum L, Walby F, Johannessen JO, Melle I, Andreassen O (2020)
Strong claims - weak basis
Tidsskr. Nor. Laegeforen., 140 (14), 1421

Reponen EJ, Dieset I, Tesli M, Mørch RH, Aas M, Vedal TSJ, Haug E, Drange OK, Steen NE, Hope S, Szabo A, Gohar SM, Wedervang-Resell K, Djurovic S, Melle I, Aukrust P, Andreassen OA, Ueland T (2020)
Atherogenic Lipid Ratios Related to Myeloperoxidase and C-Reactive Protein Levels in Psychotic Disorders
Front Psychiatry, 11, 672
DOI 10.3389/fpsyt.2020.00672, PubMed 32754070

Richards AL, Pardiñas AF, Frizzati A, Tansey KE, Lynham AJ, Holmans P, Legge SE, Savage JE, Agartz I, Andreassen OA, Blokland GAM, Corvin A, Cosgrove D, Degenhardt F, Djurovic S, Espeseth T, Ferraro L, Gayer-Anderson C, Giegling I, van Haren NE, Hartmann AM, Hubert JJ, Jönsson EG, Konte B, Lennertz L et al. (2020)
The Relationship Between Polygenic Risk Scores and Cognition in Schizophrenia
Schizophr Bull, 46 (2), 336-344
DOI 10.1093/schbul/sbz061, PubMed 31206164

Rokicki J, Wolfers T, Nordhøy W, Tesli N, Quintana DS, Alnaes D, Richard G, de Lange AG, Lund MJ, Norbom L, Agartz I, Melle I, Naerland T, Selbaek G, Persson K, Nordvik JE, Schwarz E, Andreassen OA, Kaufmann T, Westlye LT (2020)
Multimodal imaging improves brain age prediction and reveals distinct abnormalities in patients with psychiatric and neurological disorders
Hum Brain Mapp, 42 (6), 1714-1726
DOI 10.1002/hbm.25323, PubMed 33340180

Romm KL, Nilsen L, Gjermundsen K, Holter M, Fjell A, Melle I, Repål A, Lobban F (2020)
Remote Care for Caregivers of People With Psychosis: Mixed Methods Pilot Study
JMIR Ment Health, 7 (7), e19497
DOI 10.2196/19497, PubMed 32720905

Storvestre GB, Jensen A, Bjerke E, Tesli N, Rosaeg C, Friestad C, Andreassen OA, Melle I, Haukvik UK (2020)
Childhood Trauma in Persons With Schizophrenia and a History of Interpersonal Violence
Front Psychiatry, 11, 383
DOI 10.3389/fpsyt.2020.00383, PubMed 32431632

Svendsen IH, Øie MG, Møller P, Nelson B, Melle I, Haug E (2020)
Basic self-disturbances are associated with Sense of Coherence in patients with psychotic disorders
PLoS One, 15 (4), e0230956
DOI 10.1371/journal.pone.0230956, PubMed 32294097

Szabo A, Akkouh IA, Ueland T, Lagerberg TV, Dieset I, Bjella T, Aukrust P, Le Hellard S, Stavrum AK, Melle I, Andreassen OA, Djurovic S (2020)
Cannabis Use Is Associated With Increased Levels of Soluble gp130 in Schizophrenia but Not in Bipolar Disorder
Front Psychiatry, 11, 642
DOI 10.3389/fpsyt.2020.00642, PubMed 32714224

Tesli N, van der Meer D, Rokicki J, Storvestre G, Røsæg C, Jensen A, Hjell G, Bell C, Fischer-Vieler T, Tesli M, Andreassen OA, Melle I, Agartz I, Haukvik UK (2020)
Hippocampal subfield and amygdala nuclei volumes in schizophrenia patients with a history of violence
Eur Arch Psychiatry Clin Neurosci, 270 (6), 771-782
DOI 10.1007/s00406-020-01098-y, PubMed 31980898

Vaskinn A, Haatveit B, Melle I, Andreassen OA, Ueland T, Sundet K (2020)
Cognitive Heterogeneity across Schizophrenia and Bipolar Disorder: A Cluster Analysis of Intellectual Trajectories
J Int Neuropsychol Soc, 26 (9), 860-872
DOI 10.1017/S1355617720000442, PubMed 32423506

Vaskinn A, Melle I, Aas M, Berg AO (2020)
Sexual abuse and physical neglect in childhood are associated with affective theory of mind in adults with schizophrenia
Schizophr Res Cogn, 23, 100189
DOI 10.1016/j.scog.2020.100189, PubMed 33134093

Werner MCF, Wirgenes KV, Haram M, Bettella F, Lunding SH, Rødevand L, Hjell G, Agartz I, Djurovic S, Melle I, Andreassen OA, Steen NE (2020)
Indicated association between polygenic risk score and treatment-resistance in a naturalistic sample of patients with schizophrenia spectrum disorders
Schizophr Res, 218, 55-62
DOI 10.1016/j.schres.2020.03.006, PubMed 32171635

Widing L, Simonsen C, Flaaten CB, Haatveit B, Vik RK, Wold KF, Åsbø G, Ueland T, Melle I (2020)
Symptom Profiles in Psychotic Disorder Not Otherwise Specified
Front Psychiatry, 11, 580444
DOI 10.3389/fpsyt.2020.580444, PubMed 33281644

Aas M, Ueland T, Inova A, Melle I, Andreassen OA, Steen NE (2020)
Childhood Trauma Is Nominally Associated With Elevated Cortisol Metabolism in Severe Mental Disorder
Front Psychiatry, 11, 391
DOI 10.3389/fpsyt.2020.00391, PubMed 32528319

Publications 2019

Bauer M, Glenn T, Alda M, Andreassen OA, Angelopoulos E, Ardau R, Ayhan Y, Baethge C, Bauer R, Baune BT, Becerra-Palars C, Bellivier F, Belmaker RH, Berk M, Bersudsky Y, Bicakci Ş, Birabwa-Oketcho H, Bjella TD, Cabrera J, Wo Cheung EY, Del Zompo M, Dodd S, Donix M, Etain B, Fagiolini A et al. (2019)
Association between solar insolation and a history of suicide attempts in bipolar I disorder
J Psychiatr Res, 113, 1-9
DOI 10.1016/j.jpsychires.2019.03.001, PubMed 30878786

Bjornestad J, Hegelstad WTV, Berg H, Davidson L, Joa I, Johannessen JO, Melle I, Stain HJ, Pallesen S (2019)
Social Media and Social Functioning in Psychosis: A Systematic Review
J Med Internet Res, 21 (6), e13957
DOI 10.2196/13957, PubMed 31254338

Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, Bis JC, Burdick KE, Christoforou A, DeRosse P, Djurovic S, Espeseth T, Giakoumaki S, Giddaluru S, Gustavson DE, Hayward C et al. (2019)
Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
Nat Commun, 10 (1), 2068
DOI 10.1038/s41467-019-10160-w, PubMed 31043617

Di Sero A, Jørgensen KN, Nerland S, Melle I, Andreassen OA, Jovicich J, Agartz I (2019)
Antipsychotic treatment and basal ganglia volumes: Exploring the role of receptor occupancy, dosage and remission status
Schizophr Res, 208, 114-123
DOI 10.1016/j.schres.2019.04.002, PubMed 31006616

Engen MJ, Simonsen C, Melle I, Færden A, Lyngstad SH, Haatveit B, Vaskinn A, Ueland T (2019)
Cognitive functioning in patients with first-episode psychosis stratified by level of negative symptoms: A 1-year follow-up study
Psychiatry Res, 281, 112554
DOI 10.1016/j.psychres.2019.112554, PubMed 31499342

Ferrara M, Guloksuz S, Li F, Burke S, Tek C, Friis S, Ten Velden Hegelstad W, Joa I, Johannessen JO, Melle I, Simonsen E, Srihari VH (2019)
Parsing the impact of early detection on duration of untreated psychosis (DUP): Applying quantile regression to data from the Scandinavian TIPS study
Schizophr Res, 210, 128-134
DOI 10.1016/j.schres.2019.05.035, PubMed 31204063

Friis S, Melle I, McGlashan TH (2019)
Symptom remission at 12-weeks is a strong predictor for long term outcome
Psychol Med, 50 (14), 2464
DOI 10.1017/S0033291719003465, PubMed 31814559

Gjerde PB, Simonsen CE, Lagerberg TV, Steen NE, Ueland T, Andreassen OA, Steen VM, Melle I (2019)
Improvement in verbal learning over the first year of antipsychotic treatment is associated with serum HDL levels in a cohort of first episode psychosis patients
Eur Arch Psychiatry Clin Neurosci, 270 (1), 49-58
DOI 10.1007/s00406-019-01017-w, PubMed 31028479

Gohar SM, Dieset I, Steen NE, Mørch RH, Vedal TSJ, Reponen EJ, Steen VM, Andreassen OA, Melle I (2019)
Association between leptin levels and severity of suicidal behaviour in schizophrenia spectrum disorders
Acta Psychiatr Scand, 139 (5), 464-471
DOI 10.1111/acps.13019, PubMed 30848483

Icick R, Melle I, Etain B, Ringen PA, Aminoff SR, Leboyer M, Aas M, Henry C, Bjella TD, Andreassen OA, Bellivier F, Lagerberg TV (2019)
Tobacco smoking and other substance use disorders associated with recurrent suicide attempts in bipolar disorder
J Affect Disord, 256, 348-357
DOI 10.1016/j.jad.2019.05.075, PubMed 31202989

Kaufmann T, van der Meer D, Doan NT, Schwarz E, Lund MJ, Agartz I, Alnæs D, Barch DM, Baur-Streubel R, Bertolino A, Bettella F, Beyer MK, Bøen E, Borgwardt S, Brandt CL, Buitelaar J, Celius EG, Cervenka S, Conzelmann A, Córdova-Palomera A, Dale AM, de Quervain DJF, Di Carlo P, Djurovic S, Dørum ES et al. (2019)
Common brain disorders are associated with heritable patterns of apparent aging of the brain
Nat Neurosci, 22 (10), 1617-1623
DOI 10.1038/s41593-019-0471-7, PubMed 31551603

Lam M, Hill WD, Trampush JW, Yu J, Knowles E, Davies G, Stahl E, Huckins L, Liewald DC, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, Räikkönen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Hartmann AM et al. (2019)
Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways
Am J Hum Genet, 105 (2), 334-350
DOI 10.1016/j.ajhg.2019.06.012, PubMed 31374203

Laskemoen JF, Büchmann C, Barrett EA, Collier-Høegh M, Haatveit B, Vedal TJ, Ueland T, Melle I, Aas M, Simonsen C (2019)
Do sleep disturbances contribute to cognitive impairments in schizophrenia spectrum and bipolar disorders?
Eur Arch Psychiatry Clin Neurosci, 270 (6), 749-759
DOI 10.1007/s00406-019-01075-0, PubMed 31587109

Laskemoen JF, Simonsen C, Büchmann C, Barrett EA, Bjella T, Lagerberg TV, Vedal TJ, Andreassen OA, Melle I, Aas M (2019)
Sleep disturbances in schizophrenia spectrum and bipolar disorders - a transdiagnostic perspective
Compr Psychiatry, 91, 6-12
DOI 10.1016/j.comppsych.2019.02.006, PubMed 30856497

Melle I (2019)
Cognition in schizophrenia: a marker of underlying neurodevelopmental problems?
World Psychiatry, 18 (2), 164-165
DOI 10.1002/wps.20646, PubMed 31059634

Mucci A, Vignapiano A, Bitter I, Austin SF, Delouche C, Dollfus S, Erfurth A, Fleischhacker WW, Giordano GM, Gladyshev I, Glenthøj B, Gütter K, Hofer A, Hubeňák J, Kaiser S, Libiger J, Melle I, Nielsen MØ, Papsuev O, Rybakowski JK, Sachs G, Üçok A, Wojciak P, Galderisi S (2019)
A large European, multicenter, multinational validation study of the Brief Negative Symptom Scale
Eur Neuropsychopharmacol, 29 (8), 947-959
DOI 10.1016/j.euroneuro.2019.05.006, PubMed 31255394

Mullins N, Bigdeli TB, Børglum AD, Coleman JRI, Demontis D, Mehta D, Power RA, Ripke S, Stahl EA, Starnawska A, Anjorin A, M.R.C.Psych, Corvin A, Sanders AR, Forstner AJ, Reif A, Koller AC, Świątkowska B, Baune BT, Müller-Myhsok B, Penninx BWJH, Pato C, Zai C, Rujescu D, Hougaard DM et al. (2019)
GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores
Am J Psychiatry, 176 (8), 651-660
DOI 10.1176/appi.ajp.2019.18080957, PubMed 31164008

Mørch RH, Dieset I, Færden A, Reponen EJ, Hope S, Hoseth EZ, Gardsjord ES, Aas M, Iversen T, Joa I, Morken G, Agartz I, Melle I, Aukrust P, Djurovic S, Ueland T, Andreassen OA (2019)
Inflammatory markers are altered in severe mental disorders independent of comorbid cardiometabolic disease risk factors
Psychol Med, 49 (10), 1749-1757
DOI 10.1017/S0033291718004142, PubMed 30688187

Mørch RH, Dieset I, Færden A, Reponen EJ, Hope S, Hoseth EZ, Gardsjord ES, Aas M, Iversen T, Joa I, Morken G, Agartz I, Melle I, Aukrust P, Djurovic S, Ueland T, Andreassen OA (2019)
Inflammatory markers are altered in severe mental disorders independent of comorbid cardiometabolic disease risk factors - ERRATUM
Psychol Med, 49 (10), 1758
DOI 10.1017/S0033291719000291, PubMed 30803457

Onyeka IN, Collier Høegh M, Nåheim Eien EM, Nwaru BI, Melle I (2019)
Comorbidity of Physical Disorders Among Patients With Severe Mental Illness With and Without Substance Use Disorders: A Systematic Review and Meta-Analysis
J Dual Diagn, 15 (3), 192-206
DOI 10.1080/15504263.2019.1619007, PubMed 31164045

Ringen PA, Reponen EJ, Vedal TSJ, Andreassen OA, Steen NE, Melle I (2019)
Predictors for Antipsychotic Dosage Change in the First Year of Treatment in Schizophrenia Spectrum and Bipolar Disorders
Front Psychiatry, 10, 649
DOI 10.3389/fpsyt.2019.00649, PubMed 31551838

Romm KL, Gardsjord ES, Gjermundsen K, Aguirre Ulloa M, Berentzen LC, Melle I (2019)
Designing easy access to care for first-episode psychosis in complex organizations
Early Interv Psychiatry, 13 (5), 1276-1282
DOI 10.1111/eip.12802, PubMed 30919597

Rødevand L, Steen NE, Elvsåshagen T, Quintana DS, Reponen EJ, Mørch RH, Lunding SH, Vedal TSJ, Dieset I, Melle I, Lagerberg TV, Andreassen OA (2019)
Cardiovascular risk remains high in schizophrenia with modest improvements in bipolar disorder during past decade
Acta Psychiatr Scand, 139 (4), 348-360
DOI 10.1111/acps.13008, PubMed 30697685

Satizabal CL, Adams HHH, Hibar DP, White CC, Knol MJ, Stein JL, Scholz M, Sargurupremraj M, Jahanshad N, Roshchupkin GV, Smith AV, Bis JC, Jian X, Luciano M, Hofer E, Teumer A, van der Lee SJ, Yang J, Yanek LR, Lee TV, Li S, Hu Y, Koh JY, Eicher JD, Desrivières S et al. (2019)
Genetic architecture of subcortical brain structures in 38,851 individuals
Nat Genet, 51 (11), 1624-1636
DOI 10.1038/s41588-019-0511-y, PubMed 31636452

Simonsen C, Aminoff SR, Vaskinn A, Barrett EA, Faerden A, Ueland T, Andreassen OA, Romm KL, Melle I (2019)
Perceived and experienced stigma in first-episode psychosis: A 1-year follow-up study
Compr Psychiatry, 95, 152134
DOI 10.1016/j.comppsych.2019.152134, PubMed 31669787

Stahl EA, Breen G, Forstner AJ, McQuillin A, Ripke S, Trubetskoy V, Mattheisen M, Wang Y, Coleman JRI, Gaspar HA, de Leeuw CA, Steinberg S, Pavlides JMW, Trzaskowski M, Byrne EM, Pers TH, Holmans PA, Richards AL, Abbott L, Agerbo E, Akil H, Albani D, Alliey-Rodriguez N, Als TD, Anjorin A et al. (2019)
Genome-wide association study identifies 30 loci associated with bipolar disorder
Nat Genet, 51 (5), 793-803
DOI 10.1038/s41588-019-0397-8, PubMed 31043756

Steen NE, Dieset I, Hope S, Vedal TSJ, Smeland OB, Matson W, Kaddurah-Daouk R, Agartz I, Melle I, Djurovic S, Jönsson EG, Bogdanov M, Andreassen OA (2019)
Metabolic dysfunctions in the kynurenine pathway, noradrenergic and purine metabolism in schizophrenia and bipolar disorders
Psychol Med, 50 (4), 595-606
DOI 10.1017/S0033291719000400, PubMed 30867076

Storvestre GB, Valnes LM, Jensen A, Nerland S, Tesli N, Hymer KE, Rosaeg C, Server A, Ringen PA, Jacobsen M, Andreassen OA, Agartz I, Melle I, Haukvik UK (2019)
A preliminary study of cortical morphology in schizophrenia patients with a history of violence
Psychiatry Res Neuroimaging, 288, 29-36
DOI 10.1016/j.pscychresns.2019.04.013, PubMed 31071542

Svendsen IH, Øie MG, Møller P, Nelson B, Haug E, Melle I (2019)
Basic self-disturbances independently predict recovery in psychotic disorders: A seven year follow-up study
Schizophr Res, 212, 72-78
DOI 10.1016/j.schres.2019.08.009, PubMed 31420200

Sönmez N, Romm KL, Østefjells T, Grande M, Jensen LH, Hummelen B, Tesli M, Melle I, Røssberg JI (2019)
Cognitive behavior therapy in early psychosis with a focus on depression and low self-esteem: A randomized controlled trial
Compr Psychiatry, 97, 152157
DOI 10.1016/j.comppsych.2019.152157, PubMed 31935529

Tesli N, Westlye LT, Storvestre GB, Gurholt TP, Agartz I, Melle I, Andreassen OA, Haukvik UK (2019)
White matter microstructure in schizophrenia patients with a history of violence
Eur Arch Psychiatry Clin Neurosci, 271 (4), 623-634
DOI 10.1007/s00406-019-00988-0, PubMed 30694361

Vaskinn A, Løvgren A, Egeland MK, Feyer FK, Østefjells T, Andreassen OA, Melle I, Sundet K (2019)
A randomized controlled trial of training of affect recognition (TAR) in schizophrenia shows lasting effects for theory of mind
Eur Arch Psychiatry Clin Neurosci, 269 (5), 611-620
DOI 10.1007/s00406-019-00997-z, PubMed 30826974

Vedal TSJ, Steen NE, Birkeland KI, Dieset I, Reponen EJ, Laskemoen JF, Rødevand L, Melle I, Andreassen OA, Molden E, Jönsson EG (2019)
Adipokine levels are associated with insulin resistance in antipsychotics users independently of BMI
Psychoneuroendocrinology, 103, 87-95
DOI 10.1016/j.psyneuen.2019.01.001, PubMed 30659986

Weibell MA, Johannessen JO, Auestad B, Bramness J, Brønnick K, Haahr U, Joa I, Larsen TK, Melle I, Opjordsmoen S, Rund BR, Røssberg JI, Simonsen E, Vaglum P, Stain H, Friis S, Hegelstad WTV (2019)
Early Substance Use Cessation Improves Cognition-10 Years Outcome in First-Episode Psychosis Patients
Front Psychiatry, 10, 495
DOI 10.3389/fpsyt.2019.00495, PubMed 31354551

Aas M, Bellivier F, Bettella F, Henry C, Gard S, Kahn JP, Lagerberg TV, Aminoff SR, Melle I, Leboyer M, Jamain S, Andreassen OA, Etain B (2019)
Childhood maltreatment and polygenic risk in bipolar disorders
Bipolar Disord, 22 (2), 174-181
DOI 10.1111/bdi.12851, PubMed 31628696

Aas M, Djurovic S, Ueland T, Mørch RH, Fjæra Laskemoen J, Reponen EJ, Cattaneo A, Eiel Steen N, Agartz I, Melle I, Andreassen OA (2019)
The relationship between physical activity, clinical and cognitive characteristics and BDNF mRNA levels in patients with severe mental disorders
World J Biol Psychiatry, 20 (7), 567-576
DOI 10.1080/15622975.2018.1557345, PubMed 30560709

Aas M, Elvsåshagen T, Westlye LT, Kaufmann T, Athanasiu L, Djurovic S, Melle I, van der Meer D, Martin-Ruiz C, Steen NE, Agartz I, Andreassen OA (2019)
Telomere length is associated with childhood trauma in patients with severe mental disorders
Transl Psychiatry, 9 (1), 97
DOI 10.1038/s41398-019-0432-7, PubMed 30898995

Aas M, Pizzagalli DA, Laskemoen JF, Reponen EJ, Ueland T, Melle I, Agartz I, Steen NE, Andreassen OA (2019)
Elevated hair cortisol is associated with childhood maltreatment and cognitive impairment in schizophrenia and in bipolar disorders
Schizophr Res, 213, 65-71
DOI 10.1016/j.schres.2019.01.011, PubMed 30660575

Publications 2018

Berg AO, Jørgensen KN, Nerhus M, Athanasiu L, Popejoy AB, Bettella F, Norbom LCB, Gurholt TP, Dahl SR, Andreassen OA, Djurovic S, Agartz I, Melle I (2018)
Vitamin D levels, brain volume, and genetic architecture in patients with psychosis
PLoS One, 13 (8), e0200250
DOI 10.1371/journal.pone.0200250, PubMed 30142216

Bjornestad J, Veseth M, Davidson L, Joa I, Johannessen JO, Larsen TK, Melle I, Hegelstad WTV (2018)
Psychotherapy in Psychosis: Experiences of Fully Recovered Service Users
Front Psychol, 9, 1675
DOI 10.3389/fpsyg.2018.01675, PubMed 30233476

Brainstorm Consortium, Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, Lee PH, Turley P, Grenier-Boley B, Chouraki V, Kamatani Y, Berr C, Letenneur L, Hannequin D, Amouyel P, Boland A et al. (2018)
Analysis of shared heritability in common disorders of the brain
Science, 360 (6395)
DOI 10.1126/science.aap8757, PubMed 29930110

Büchmann CB, Pedersen G, Aminoff SR, Laskemoen JF, Barrett EA, Melle I, Lagerberg TV (2018)
Validity of the Birchwood insight scale in patients with schizophrenia spectrum- and bipolar disorders
Psychiatry Res, 272, 715-722
DOI 10.1016/j.psychres.2018.12.072, PubMed 30832191

Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, Bis JC, Burdick KE, Christoforou A, DeRosse P, Djurovic S, Espeseth T, Giakoumaki S, Giddaluru S, Gustavson DE, Hayward C et al. (2018)
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
Nat Commun, 9 (1), 2098
DOI 10.1038/s41467-018-04362-x, PubMed 29844566

Dieset I, Mørch RH, Hope S, Hoseth EZ, Reponen EJ, Gran JM, Aas M, Michelsen AE, Reichborn-Kjennerud T, Nesvåg R, Agartz I, Melle I, Aukrust P, Djurovic S, Ueland T, Andreassen OA (2018)
An association between YKL-40 and type 2 diabetes in psychotic disorders
Acta Psychiatr Scand, 139 (1), 37-45
DOI 10.1111/acps.12971, PubMed 30328100

Faerden A, Lyngstad SH, Simonsen C, Ringen PA, Papsuev O, Dieset I, Andreassen OA, Agartz I, Marder SR, Melle I (2018)
Reliability and validity of the self-report version of the apathy evaluation scale in first-episode Psychosis: Concordance with the clinical version at baseline and 12 months follow-up
Psychiatry Res, 267, 140-147
DOI 10.1016/j.psychres.2018.05.065, PubMed 29906681

Gardsjord ES, Romm KL, Røssberg JI, Friis S, Barder HE, Evensen J, Haahr U, Ten Velden Hegelstad W, Joa I, Johannessen JO, Langeveld J, Larsen TK, Opjordsmoen S, Rund BR, Simonsen E, Vaglum P, Melle I (2018)
Depression and functioning are important to subjective quality of life after a first episode psychosis
Compr Psychiatry, 86, 107-114
DOI 10.1016/j.comppsych.2018.07.014, PubMed 30114656

Gjerde PB, Jørgensen KN, Steen NE, Melle I, Andreassen OA, Steen VM, Agartz I (2018)
Association between olanzapine treatment and brain cortical thickness and gray/white matter contrast is moderated by cholesterol in psychotic disorders
Psychiatry Res Neuroimaging, 282, 55-63
DOI 10.1016/j.pscychresns.2018.10.001, PubMed 30415175

Gohar SM, Dieset I, Steen NE, Mørch RH, Iversen TS, Steen VM, Andreassen OA, Melle I (2018)
Association between serum lipid levels, osteoprotegerin and depressive symptomatology in psychotic disorders
Eur Arch Psychiatry Clin Neurosci, 269 (7), 795-802
DOI 10.1007/s00406-018-0897-z, PubMed 29721726

Gurholt TP, Nerhus M, Osnes K, Berg AO, Andreassen OA, Melle I, Agartz I (2018)
Hippocampus volume reduction in psychosis spectrum could be ameliorated by vitamin D
Schizophr Res, 199, 433-435
DOI 10.1016/j.schres.2018.03.011, PubMed 29555212

Gurholt TP, Osnes K, Nerhus M, Jørgensen KN, Lonning V, Berg AO, Andreassen OA, Melle I, Agartz I (2018)
Vitamin D, Folate and the Intracranial Volume in Schizophrenia and Bipolar Disorder and Healthy Controls
Sci Rep, 8 (1), 10817
DOI 10.1038/s41598-018-29141-y, PubMed 30018414

Hoseth EZ, Krull F, Dieset I, Mørch RH, Hope S, Gardsjord ES, Steen NE, Melle I, Brattbakk HR, Steen VM, Aukrust P, Djurovic S, Andreassen OA, Ueland T (2018)
Exploring the Wnt signaling pathway in schizophrenia and bipolar disorder
Transl Psychiatry, 8 (1), 55
DOI 10.1038/s41398-018-0102-1, PubMed 29507296

Hoseth EZ, Krull F, Dieset I, Mørch RH, Hope S, Gardsjord ES, Steen NE, Melle I, Brattbakk HR, Steen VM, Aukrust P, Djurovic S, Andreassen OA, Ueland T (2018)
Attenuated Notch signaling in schizophrenia and bipolar disorder
Sci Rep, 8 (1), 5349
DOI 10.1038/s41598-018-23703-w, PubMed 29593239

Lam M, Trampush JW, Yu J, Knowles E, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, Räikkönen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Roussos P, Giakoumaki S, Burdick KE, Payton A, Ollier W, Chiba-Falek O et al. (2018)
Multi-Trait Analysis of GWAS and Biological Insights Into Cognition: A Response to Hill (2018)
Twin Res Hum Genet, 21 (5), 394-397
DOI 10.1017/thg.2018.46, PubMed 30001766

Lyngstad SH, Gardsjord ES, Simonsen C, Engen MJ, Romm KL, Melle I, Færden A (2018)
Consequences of persistent depression and apathy in first-episode psychosis - A one-year follow-up study
Compr Psychiatry, 86, 60-66
DOI 10.1016/j.comppsych.2018.07.015, PubMed 30081208

Mørch-Johnsen L, Nerland S, Jørgensen KN, Osnes K, Hartberg CB, Andreassen OA, Melle I, Nesvåg R, Agartz I (2018)
Cortical thickness abnormalities in bipolar disorder patients with a lifetime history of auditory hallucinations
Bipolar Disord, 20 (7), 647-657
DOI 10.1111/bdi.12627, PubMed 29441665

Savage JE, Jansen PR, Stringer S, Watanabe K, Bryois J, de Leeuw CA, Nagel M, Awasthi S, Barr PB, Coleman JRI, Grasby KL, Hammerschlag AR, Kaminski JA, Karlsson R, Krapohl E, Lam M, Nygaard M, Reynolds CA, Trampush JW, Young H, Zabaneh D, Hägg S, Hansell NK, Karlsson IK, Linnarsson S et al. (2018)
Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence
Nat Genet, 50 (7), 912-919
DOI 10.1038/s41588-018-0152-6, PubMed 29942086

Simonsen C, Faerden A, Ueland T, Vaskinn A, Bjella T, Andreassen O, Romm KL, Melle I (2018)
Self-rated disability in first treated episode of psychosis: A 1-year follow-up study
Compr Psychiatry, 85, 48-54
DOI 10.1016/j.comppsych.2018.06.004, PubMed 29981504

Skåtun KC, Kaufmann T, Brandt CL, Doan NT, Alnæs D, Tønnesen S, Biele G, Vaskinn A, Melle I, Agartz I, Andreassen OA, Westlye LT (2018)
Thalamo-cortical functional connectivity in schizophrenia and bipolar disorder
Brain Imaging Behav, 12 (3), 640-652
DOI 10.1007/s11682-017-9714-y, PubMed 28444556

Srinivasan S, Bettella F, Frei O, Hill WD, Wang Y, Witoelar A, Schork AJ, Thompson WK, Davies G, Desikan RS, Deary IJ, Melle I, Ueland T, Dale AM, Djurovic S, Smeland OB, Andreassen OA (2018)
Enrichment of genetic markers of recent human evolution in educational and cognitive traits
Sci Rep, 8 (1), 12585
DOI 10.1038/s41598-018-30387-9, PubMed 30135563

Svendsen IH, Øie MG, Møller P, Nelson B, Melle I, Haug E (2018)
Stability in basic self-disturbances and diagnosis in a first treated psychosis: A seven year follow-up study
Schizophr Res, 202, 274-280
DOI 10.1016/j.schres.2018.07.011, PubMed 30007869

van der Meer D, Rokicki J, Kaufmann T, Córdova-Palomera A, Moberget T, Alnæs D, Bettella F, Frei O, Doan NT, Sønderby IE, Smeland OB, Agartz I, Bertolino A, Bralten J, Brandt CL, Buitelaar JK, Djurovic S, van Donkelaar M, Dørum ES, Espeseth T, Faraone SV, Fernández G, Fisher SE, Franke B, Haatveit B et al. (2018)
Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes
Mol Psychiatry, 25 (11), 3053-3065
DOI 10.1038/s41380-018-0262-7, PubMed 30279459

van Erp TGM, Walton E, Hibar DP, Schmaal L, Jiang W, Glahn DC, Pearlson GD, Yao N, Fukunaga M, Hashimoto R, Okada N, Yamamori H, Bustillo JR, Clark VP, Agartz I, Mueller BA, Cahn W, de Zwarte SMC, Hulshoff Pol HE, Kahn RS, Ophoff RA, van Haren NEM, Andreassen OA, Dale AM, Doan NT et al. (2018)
Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium
Biol Psychiatry, 84 (9), 644-654
DOI 10.1016/j.biopsych.2018.04.023, PubMed 29960671

Vedal TSJ, Steen NE, Birkeland KI, Dieset I, Reponen EJ, Laskemoen JF, Rødevand L, Melle I, Andreassen OA, Molden E, Jönsson EG (2018)
Free thyroxine and thyroid-stimulating hormone in severe mental disorders: A naturalistic study with focus on antipsychotic medication
J Psychiatr Res, 106, 74-81
DOI 10.1016/j.jpsychires.2018.09.014, PubMed 30292780

Vedal TSJ, Steen NE, Birkeland KI, Dieset I, Reponen EJ, Laskemoen JF, Rødevand L, Melle I, Andreassen OA, Molden E, Jönsson EG (2018)
Response: Are thyroid abnormalities only related to antipsychotic treatment in patients with severe mental disorders?
J Psychiatr Res, 117, 150
DOI 10.1016/j.jpsychires.2018.11.012, PubMed 30454945

Wolfers T, Doan NT, Kaufmann T, Alnæs D, Moberget T, Agartz I, Buitelaar JK, Ueland T, Melle I, Franke B, Andreassen OA, Beckmann CF, Westlye LT, Marquand AF (2018)
Mapping the Heterogeneous Phenotype of Schizophrenia and Bipolar Disorder Using Normative Models
JAMA Psychiatry, 75 (11), 1146-1155
DOI 10.1001/jamapsychiatry.2018.2467, PubMed 30304337

Aas M, Dieset I, Mørch R, Steen NE, Hope S, Reponen EJ, Laskemoen JF, Ueland T, Aukrust P, Melle I, Agartz I, Andreassen OA (2018)
Reduced brain-derived neurotrophic factor is associated with childhood trauma experiences and number of depressive episodes in severe mental disorders
Schizophr Res, 205, 45-50
DOI 10.1016/j.schres.2018.08.007, PubMed 30126813

Publications 2017

Bauer M, Glenn T, Alda M, Aleksandrovich MA, Andreassen OA, Angelopoulos E, Ardau R, Ayhan Y, Baethge C, Bharathram SR, Bauer R, Baune BT, Becerra-Palars C, Bellivier F, Belmaker RH, Berk M, Bersudsky Y, Bicakci Ş, Birabwa-Oketcho H, Bjella TD, Bossini L, Cabrera J, Cheung EYW, Del Zompo M, Dodd S et al. (2017)
Solar insolation in springtime influences age of onset of bipolar I disorder
Acta Psychiatr Scand, 136 (6), 571-582
DOI 10.1111/acps.12772, PubMed 28722128

Bjornestad J, Bronnick K, Davidson L, Hegelstad WT, Joa I, Kandal O, Larsen TK, Langeveld J, Veseth M, Melle I, Johannessen JO (2017)
The central role of self-agency in clinical recovery from first episode psychosis
Psychosis, 9 (2), 140-148
DOI 10.1080/17522439.2016.1198828

Bjornestad J, Davidson L, Joa I, Larsen TK, Hegelstad WTV, Langeveld J, Veseth M, Melle I, Johannessen JO, Bronnick K (2017)
Antipsychotic treatment: experiences of fully recovered service users
J Ment Health, 26 (3), 264-270
DOI 10.1080/09638237.2017.1294735, PubMed 28602144

Bjornestad J, Hegelstad WTV, Joa I, Davidson L, Larsen TK, Melle I, Veseth M, Johannessen JO, Bronnick K (2017)
"With a little help from my friends" social predictors of clinical recovery in first-episode psychosis
Psychiatry Res, 255, 209-214
DOI 10.1016/j.psychres.2017.05.041, PubMed 28578180

Church C, Andreassen OA, Lorentzen S, Melle I, Aas M (2017)
Childhood Trauma and Minimization/Denial in People with and without a Severe Mental Disorder
Front Psychol, 8, 1276
DOI 10.3389/fpsyg.2017.01276, PubMed 28883800

Demmo C, Lagerberg TV, Kvitland LR, Aminoff SR, Hellvin T, Simonsen C, Haatveit B, Andreassen OA, Melle I, Ueland T (2017)
Neurocognitive functioning, clinical course and functional outcome in first-treatment bipolar I disorder patients with and without clinical relapse: A 1-year follow-up study
Bipolar Disord, 20 (3), 228-237
DOI 10.1111/bdi.12569, PubMed 29121444

Doan NT, Kaufmann T, Bettella F, Jørgensen KN, Brandt CL, Moberget T, Alnæs D, Douaud G, Duff E, Djurovic S, Melle I, Ueland T, Agartz I, Andreassen OA, Westlye LT (2017)
Distinct multivariate brain morphological patterns and their added predictive value with cognitive and polygenic risk scores in mental disorders
Neuroimage Clin, 15, 719-731
DOI 10.1016/j.nicl.2017.06.014, PubMed 28702349

Gardsjord ES, Romm KL, Røssberg JI, Friis S, Barder HE, Evensen J, Haahr U, Ten Velden Hegelstad W, Joa I, Johannessen JO, Langeveld J, Larsen TK, Opjordsmoen S, Rund BR, Simonsen E, Vaglum P, McGlashan T, Melle I (2017)
Is going into stable symptomatic remission associated with a more positive development of life satisfaction? A 10-year follow-up study of first episode psychosis
Schizophr Res, 193, 364-369
DOI 10.1016/j.schres.2017.07.006, PubMed 28701275

Gjerde PB, Dieset I, Simonsen C, Hoseth EZ, Iversen T, Lagerberg TV, Lyngstad SH, Mørch RH, Skrede S, Andreassen OA, Melle I, Steen VM (2017)
Increase in serum HDL level is associated with less negative symptoms after one year of antipsychotic treatment in first-episode psychosis
Schizophr Res, 197, 253-260
DOI 10.1016/j.schres.2017.10.042, PubMed 29129510

Hartberg CB, Lange EH, Lagerberg TV, Haukvik UK, Andreassen OA, Melle I, Agartz I (2017)
Cortical thickness, cortical surface area and subcortical volumes in schizophrenia and bipolar disorder patients with cannabis use
Eur Neuropsychopharmacol, 28 (1), 37-47
DOI 10.1016/j.euroneuro.2017.11.019, PubMed 29254657

Hibar DP, Adams HHH, Jahanshad N, Chauhan G, Stein JL, Hofer E, Renteria ME, Bis JC, Arias-Vasquez A, Ikram MK, Desrivières S, Vernooij MW, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Armstrong NJ, Athanasiu L, Axelsson T, Beecham AH, Beiser A, Bernard M, Blanton SH et al. (2017)
Novel genetic loci associated with hippocampal volume
Nat Commun, 8, 13624
DOI 10.1038/ncomms13624, PubMed 28098162

Hoseth EZ, Ueland T, Dieset I, Birnbaum R, Shin JH, Kleinman JE, Hyde TM, Mørch RH, Hope S, Lekva T, Abraityte AJ, Michelsen AE, Melle I, Westlye LT, Ueland T, Djurovic S, Aukrust P, Weinberger DR, Andreassen OA (2017)
A Study of TNF Pathway Activation in Schizophrenia and Bipolar Disorder in Plasma and Brain Tissue
Schizophr Bull, 43 (4), 881-890
DOI 10.1093/schbul/sbw183, PubMed 28049760

Iversen TSJ, Steen NE, Dieset I, Hope S, Mørch R, Gardsjord ES, Jørgensen KN, Melle I, Andreassen OA, Molden E, Jönsson EG (2017)
Side effect burden of antipsychotic drugs in real life - Impact of gender and polypharmacy
Prog Neuropsychopharmacol Biol Psychiatry, 82, 263-271
DOI 10.1016/j.pnpbp.2017.11.004, PubMed 29122637

Lam M, Trampush JW, Yu J, Knowles E, Davies G, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, Räikkönen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Roussos P, Giakoumaki S, Burdick KE et al. (2017)
Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets
Cell Rep, 21 (9), 2597-2613
DOI 10.1016/j.celrep.2017.11.028, PubMed 29186694

Langeveld J, Bjørkly S, Evensen J, Joa I, Johannessen JO, Larsen TK, Melle I, Opjordsmoen S, Røssberg JI, Rund BR, Simonsen E, Vaglum P, Velden WT, McGlashan T, Friis S (2017)
A 10-year follow-up study of violent victimization in first episode psychosis: Risk and protective factors
Psychiatry Res, 259, 545-549
DOI 10.1016/j.psychres.2017.11.013, PubMed 29172178

Le Hellard S, Wang Y, Witoelar A, Zuber V, Bettella F, Hugdahl K, Espeseth T, Steen VM, Melle I, Desikan R, Schork AJ, Thompson WK, Dale AM, Djurovic S, Andreassen OA, Schizophrenia Working Group of the Psychiatric Genomics Consortium (2017)
Identification of Gene Loci That Overlap Between Schizophrenia and Educational Attainment
Schizophr Bull, 43 (3), 654-664
DOI 10.1093/schbul/sbw085, PubMed 27338279

Melle I, Olav Johannesen J, Haahr UH, Ten Velden Hegelstad W, Joa I, Langeveld J, Larsen TK, Ilner Opjordsmoen S, Qin P, Ivar Røssberg J, Rishovd Rund B, Simonsen E, Vaglum PJW, McGlashan TH, Friis S (2017)
Causes and predictors of premature death in first-episode schizophrenia spectrum disorders
World Psychiatry, 16 (2), 217-218
DOI 10.1002/wps.20431, PubMed 28498600

Mellerup E, Andreassen OA, Bennike B, Dam H, Djurovic S, Jorgensen MB, Kessing LV, Koefoed P, Melle I, Mors O, Moeller GL (2017)
Combinations of genetic variants associated with bipolar disorder
PLoS One, 12 (12), e0189739
DOI 10.1371/journal.pone.0189739, PubMed 29267373

Mørch RH, Dieset I, Faerden A, Hope S, Aas M, Nerhus M, Gardsjord ES, Haram M, Falk RS, Joa I, Morken G, Agartz I, Aukrust P, Djurovic S, Melle I, Ueland T, Andreassen OA (2017)
Persistent increase in TNF and IL-1 markers in severe mental disorders suggests trait-related inflammation: a one year follow-up study
Acta Psychiatr Scand, 136 (4), 400-408
DOI 10.1111/acps.12783, PubMed 28815548

Nerhus M, Berg AO, Simonsen C, Haram M, Haatveit B, Dahl SR, Gurholt TP, Bjella TD, Ueland T, Andreassen OA, Melle I (2017)
Vitamin D Deficiency Associated With Cognitive Functioning in Psychotic Disorders
J Clin Psychiatry, 78 (7), e750-e757
DOI 10.4088/JCP.16m10880, PubMed 28493652

Nesvåg R, Jönsson EG, Bakken IJ, Knudsen GP, Bjella TD, Reichborn-Kjennerud T, Melle I, Andreassen OA (2017)
The quality of severe mental disorder diagnoses in a national health registry as compared to research diagnoses based on structured interview
BMC Psychiatry, 17 (1), 93
DOI 10.1186/s12888-017-1256-8, PubMed 28292279

Simonsen C, Faerden A, Romm KL, Berg AO, Bjella T, Sundet K, Ueland T, Andreassen O, Melle I (2017)
Early clinical recovery in first-episode psychosis: Symptomatic remission and its correlates at 1-year follow-up
Psychiatry Res, 254, 118-125
DOI 10.1016/j.psychres.2017.04.050, PubMed 28460281

Skåtun KC, Kaufmann T, Doan NT, Alnæs D, Córdova-Palomera A, Jönsson EG, Fatouros-Bergman H, Flyckt L, KaSP, Melle I, Andreassen OA, Agartz I, Westlye LT (2017)
Consistent Functional Connectivity Alterations in Schizophrenia Spectrum Disorder: A Multisite Study
Schizophr Bull, 43 (4), 914-924
DOI 10.1093/schbul/sbw145, PubMed 27872268

Srinivasan S, Bettella F, Hassani S, Wang Y, Witoelar A, Schork AJ, Thompson WK, Collier DA, Desikan RS, Melle I, Dale AM, Djurovic S, Andreassen OA (2017)
Probing the Association between Early Evolutionary Markers and Schizophrenia
PLoS One, 12 (1), e0169227
DOI 10.1371/journal.pone.0169227, PubMed 28081145

Trampush JW, Yang ML, Yu J, Knowles E, Davies G, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, Räikkönen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Roussos P, Giakoumaki S, Burdick KE et al. (2017)
GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium
Mol Psychiatry, 22 (3), 336-345
DOI 10.1038/mp.2016.244, PubMed 28093568

Trampush JW, Yang MLZ, Yu J, Knowles E, Davies G, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, Räikkönen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Roussos P, Giakoumaki S, Burdick KE et al. (2017)
GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium
Mol Psychiatry, 22 (11), 1651-1652
DOI 10.1038/mp.2017.197, PubMed 29068436

Walton E, Hibar DP, van Erp TG, Potkin SG, Roiz-Santiañez R, Crespo-Facorro B, Suarez-Pinilla P, Van Haren NE, de Zwarte SM, Kahn RS, Cahn W, Doan NT, Jørgensen KN, Gurholt TP, Agartz I, Andreassen OA, Westlye LT, Melle I, Berg AO, Mørch-Johnsen L, Faerden A, Flyckt L, Fatouros-Bergman H, Karolinska Schizophrenia Project Consortium (KaSP), Jönsson EG et al. (2017)
Positive symptoms associate with cortical thinning in the superior temporal gyrus via the ENIGMA Schizophrenia consortium
Acta Psychiatr Scand, 135 (5), 439-447
DOI 10.1111/acps.12718, PubMed 28369804

Walton E, Hibar DP, van Erp TGM, Potkin SG, Roiz-Santiañez R, Crespo-Facorro B, Suarez-Pinilla P, van Haren NEM, de Zwarte SMC, Kahn RS, Cahn W, Doan NT, Jørgensen KN, Gurholt TP, Agartz I, Andreassen OA, Westlye LT, Melle I, Berg AO, Morch-Johnsen L, Færden A, Flyckt L, Fatouros-Bergman H, Karolinska Schizophrenia Project Consortium (KaSP), Jönsson EG et al. (2017)
Prefrontal cortical thinning links to negative symptoms in schizophrenia via the ENIGMA consortium
Psychol Med, 48 (1), 82-94
DOI 10.1017/S0033291717001283, PubMed 28545597

Weibell MA, Hegelstad WTV, Auestad B, Bramness J, Evensen J, Haahr U, Joa I, Johannessen JO, Larsen TK, Melle I, Opjordsmoen S, Rund BR, Simonsen E, Vaglum P, McGlashan T, McGorry P, Friis S (2017)
The Effect of Substance Use on 10-Year Outcome in First-Episode Psychosis
Schizophr Bull, 43 (4), 843-851
DOI 10.1093/schbul/sbw179, PubMed 28199703

Østefjells T, Lystad JU, Berg AO, Hagen R, Loewy R, Sandvik L, Melle I, Røssberg JI (2017)
Metacognitive beliefs mediate the effect of emotional abuse on depressive and psychotic symptoms in severe mental disorders
Psychol Med, 47 (13), 2323-2333
DOI 10.1017/S0033291717000848, PubMed 28397634

Aas M, Dieset I, Hope S, Hoseth E, Mørch R, Reponen E, Steen NE, Laskemoen JF, Ueland T, Aukrust P, Agartz I, Andreassen OA, Melle I (2017)
Childhood maltreatment severity is associated with elevated C-reactive protein and body mass index in adults with schizophrenia and bipolar diagnoses
Brain Behav Immun, 65, 342-349
DOI 10.1016/j.bbi.2017.06.005, PubMed 28619247

Aas M, Melle I, Bettella F, Djurovic S, Le Hellard S, Bjella T, Ringen PA, Lagerberg TV, Smeland OB, Agartz I, Andreassen OA, Tesli M (2017)
Psychotic patients who used cannabis frequently before illness onset have higher genetic predisposition to schizophrenia than those who did not
Psychol Med, 48 (1), 43-49
DOI 10.1017/S0033291717001209, PubMed 28967348

Publications 2016

Adams HH, Hibar DP, Chouraki V, Stein JL, Nyquist PA, Rentería ME, Trompet S, Arias-Vasquez A, Seshadri S, Desrivières S, Beecham AH, Jahanshad N, Wittfeld K, Van der Lee SJ, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Armstrong NJ, Athanasiu L, Axelsson T, Beiser A, Bernard M et al. (2016)
Novel genetic loci underlying human intracranial volume identified through genome-wide association
Nat Neurosci, 19 (12), 1569-1582
DOI 10.1038/nn.4398, PubMed 27694991

Aleman A, Lincoln TM, Bruggeman R, Melle I, Arends J, Arango C, Knegtering H (2016)
Treatment of negative symptoms: Where do we stand, and where do we go?
Schizophr Res, 186, 55-62
DOI 10.1016/j.schres.2016.05.015, PubMed 27293137

Berg AO, Melle I, Zuber V, Simonsen C, Nerhus M, Ueland T, Andreassen OA, Sundet K, Vaskinn A (2016)
Modelling difficulties in abstract thinking in psychosis: the importance of socio-developmental background
Cogn Neuropsychiatry, 22 (1), 39-52
DOI 10.1080/13546805.2016.1259998, PubMed 28005457

Bjornestad J, Joa I, Larsen TK, Langeveld J, Davidson L, Ten Velden Hegelstad W, Anda LG, Veseth M, Melle I, Johannessen JO, Bronnick K (2016)
"Everyone Needs a Friend Sometimes" - Social Predictors of Long-Term Remission In First Episode Psychosis
Front Psychol, 7, 1491
DOI 10.3389/fpsyg.2016.01491, PubMed 27757090

Demmo C, Lagerberg TV, Aminoff SR, Hellvin T, Kvitland LR, Simonsen C, Andreassen OA, Melle I, Ueland T (2016)
History of psychosis and previous episodes as potential explanatory factors for neurocognitive impairment in first-treatment bipolar I disorder
Bipolar Disord, 18 (2), 136-47
DOI 10.1111/bdi.12377, PubMed 26990158

Demmo C, Lagerberg TV, Aminoff SR, Hellvin T, Kvitland LR, Simonsen C, Haatveit B, Andreassen OA, Melle I, Ueland T (2016)
Course of neurocognitive function in first treatment bipolar I disorder: One-year follow-up study
Psychiatry Res, 249, 286-292
DOI 10.1016/j.psychres.2016.12.048, PubMed 28142102

Gardsjord ES, Romm KL, Friis S, Barder HE, Evensen J, Haahr U, ten Velden Hegelstad W, Joa I, Johannessen JO, Langeveld J, Larsen TK, Opjordsmoen S, Rund BR, Simonsen E, Vaglum P, McGlashan T, Melle I, Røssberg JI (2016)
Subjective quality of life in first-episode psychosis. A ten year follow-up study
Schizophr Res, 172 (1-3), 23-8
DOI 10.1016/j.schres.2016.02.034, PubMed 26947210

Gunnarsson B, Jónsdóttir GA, Björnsdóttir G, Konte B, Sulem P, Kristmundsdóttir S, Kehr B, Gústafsson Ó, Helgason H, Iordache PD, Ólafsson S, Frigge ML, Þorleifsson G, Arnarsdóttir S, Stefánsdóttir B, Giegling I, Djurovic S, Sundet KS, Espeseth T, Melle I, Hartmann AM, Thorsteinsdottir U, Kong A, Guðbjartsson DF, Ettinger U et al. (2016)
A sequence variant associating with educational attainment also affects childhood cognition
Sci Rep, 6, 36189
DOI 10.1038/srep36189, PubMed 27811963

Haram M, Bettella F, Brandt CL, Quintana DS, Nerhus M, Bjella T, Djurovic S, Westlye LT, Andreassen OA, Melle I, Tesli M (2016)
Contribution of oxytocin receptor polymorphisms to amygdala activation in schizophrenia spectrum disorders
BJPsych Open, 2 (6), 353-358
DOI 10.1192/bjpo.bp.116.003376, PubMed 27847593

Haug E, Øie MG, Andreassen OA, Bratlien U, Romm KL, Møller P, Melle I (2016)
The Association between Anomalous Self-experiences, Self-esteem and Depressive Symptoms in First Episode Schizophrenia
Front Hum Neurosci, 10, 557
DOI 10.3389/fnhum.2016.00557, PubMed 27872587

Hegelstad WT, Bronnick KS, Barder HE, Evensen JH, Haahr U, Joa I, Johannessen JO, Langeveld J, Larsen TK, Melle I, Opjordsmoen S, Rund BR, Rossberg JI, Simonsen E, Vaglum PW, McGlashan TH, Friis S (2016)
Preventing Poor Vocational Functioning in Psychosis Through Early Intervention
Psychiatr Serv, 68 (1), 100-103
DOI 10.1176/appi.ps.201500451, PubMed 27582238

Haahr UH, Larsen TK, Simonsen E, Rund BR, Joa I, Rossberg JI, Johannessen JO, Langeveld J, Evensen J, Trauelsen AMH, Vaglum P, Opjordsmoen S, Hegelstad WTV, Friis S, McGlashan T, Melle I (2016)
Relation between premorbid adjustment, duration of untreated psychosis and close interpersonal trauma in first-episode psychosis
Early Interv Psychiatry, 12 (3), 316-323
DOI 10.1111/eip.12315, PubMed 26800653

Haatveit B, Jensen J, Alnæs D, Kaufmann T, Brandt CL, Thoresen C, Andreassen OA, Melle I, Ueland T, Westlye LT (2016)
Reduced load-dependent default mode network deactivation across executive tasks in schizophrenia spectrum disorders
Neuroimage Clin, 12, 389-96
DOI 10.1016/j.nicl.2016.08.012, PubMed 27622135

Jørgensen KN, Nerland S, Norbom LB, Doan NT, Nesvåg R, Mørch-Johnsen L, Haukvik UK, Melle I, Andreassen OA, Westlye LT, Agartz I (2016)
Increased MRI-based cortical grey/white-matter contrast in sensory and motor regions in schizophrenia and bipolar disorder
Psychol Med, 46 (9), 1971-85
DOI 10.1017/S0033291716000593, PubMed 27049014

Jørgensen KN, Nesvåg R, Nerland S, Mørch-Johnsen L, Westlye LT, Lange EH, Haukvik UK, Hartberg CB, Melle I, Andreassen OA, Agartz I (2016)
Brain volume change in first-episode psychosis: an effect of antipsychotic medication independent of BMI change
Acta Psychiatr Scand, 135 (2), 117-126
DOI 10.1111/acps.12677, PubMed 27925164

Kaufmann T, Alnæs D, Brandt CL, Doan NT, Kauppi K, Bettella F, Lagerberg TV, Berg AO, Djurovic S, Agartz I, Melle IS, Ueland T, Andreassen OA, Westlye LT (2016)
Task modulations and clinical manifestations in the brain functional connectome in 1615 fMRI datasets
Neuroimage, 147, 243-252
DOI 10.1016/j.neuroimage.2016.11.073, PubMed 27916665

Kvitland LR, Ringen PA, Aminoff SR, Demmo C, Hellvin T, Lagerberg TV, Andreassen OA, Melle I (2016)
Duration of untreated illness in first-treatment bipolar I disorder in relation to clinical outcome and cannabis use
Psychiatry Res, 246, 762-768
DOI 10.1016/j.psychres.2016.07.064, PubMed 27814886

Lagerberg TV, Aminoff SR, Aas M, Bjella T, Henry C, Leboyer M, Pedersen G, Bellivier F, Icick R, Andreassen OA, Etain B, Melle I (2016)
Alcohol use disorders are associated with increased affective lability in bipolar disorder
J Affect Disord, 208, 316-324
DOI 10.1016/j.jad.2016.09.062, PubMed 27810713

Lange EH, Nerland S, Jørgensen KN, Mørch-Johnsen L, Nesvåg R, Hartberg CB, Haukvik UK, Osnes K, Melle I, Andreassen OA, Agartz I (2016)
Alcohol use is associated with thinner cerebral cortex and larger ventricles in schizophrenia, bipolar disorder and healthy controls
Psychol Med, 47 (4), 655-668
DOI 10.1017/S0033291716002920, PubMed 27830632

Marshall CR, Howrigan DP, Merico D, Thiruvahindrapuram B, Wu W, Greer DS, Antaki D, Shetty A, Holmans PA, Pinto D, Gujral M, Brandler WM, Malhotra D, Wang Z, Fajarado KVF, Maile MS, Ripke S, Agartz I, Albus M, Alexander M, Amin F, Atkins J, Bacanu SA, Belliveau RA, Bergen SE et al. (2016)
Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects
Nat Genet, 49 (1), 27-35
DOI 10.1038/ng.3725, PubMed 27869829

Mørch-Johnsen L, Nesvåg R, Jørgensen KN, Lange EH, Hartberg CB, Haukvik UK, Kompus K, Westerhausen R, Osnes K, Andreassen OA, Melle I, Hugdahl K, Agartz I (2016)
Auditory Cortex Characteristics in Schizophrenia: Associations With Auditory Hallucinations
Schizophr Bull, 43 (1), 75-83
DOI 10.1093/schbul/sbw130, PubMed 27605526

Mørch RH, Dieset I, Færden A, Hope S, Aas M, Nerhus M, Gardsjord ES, Joa I, Morken G, Agartz I, Aukrust P, Djurovic S, Melle I, Ueland T, Andreassen OA (2016)
Inflammatory evidence for the psychosis continuum model
Psychoneuroendocrinology, 67, 189-97
DOI 10.1016/j.psyneuen.2016.02.011, PubMed 26923849

Nerhus M, Berg AO, Kvitland LR, Dieset I, Hope S, Dahl SR, Weibell MA, Romm KL, Faerden A, Andreassen OA, Melle I (2016)
Low vitamin D is associated with negative and depressive symptoms in psychotic disorders
Schizophr Res, 178 (1-3), 44-49
DOI 10.1016/j.schres.2016.08.024, PubMed 27595553

Ringen PA, Nesvåg R, Helle S, Lagerberg TV, Lange EH, Løberg EM, Agartz I, Andreassen OA, Melle I (2016)
Premorbid cannabis use is associated with more symptoms and poorer functioning in schizophrenia spectrum disorder
Psychol Med, 46 (15), 3127-3136
DOI 10.1017/S0033291716001999, PubMed 27534999

Skåtun KC, Kaufmann T, Tønnesen S, Biele G, Melle I, Agartz I, Alnæs D, Andreassen OA, Westlye LT (2016)
Global brain connectivity alterations in patients with schizophrenia and bipolar spectrum disorders
J Psychiatry Neurosci, 41 (5), 331-41
DOI 10.1503/jpn.150159, PubMed 26854755

Steen NE, Aas M, Simonsen C, Dieset I, Tesli M, Nerhus M, Gardsjord E, Mørch R, Agartz I, Melle I, Ueland T, Spigset O, Andreassen OA (2016)
Serum levels of second-generation antipsychotics are associated with cognitive function in psychotic disorders
World J Biol Psychiatry, 18 (6), 471-482
DOI 10.1080/15622975.2016.1245441, PubMed 27712130

Steen NE, Aas M, Simonsen C, Dieset I, Tesli M, Nerhus M, Gardsjord E, Mørch R, Agartz I, Melle I, Vaskinn A, Spigset O, Andreassen OA (2016)
Serum concentrations of mood stabilizers are associated with memory, but not other cognitive domains in psychosis spectrum disorders; explorative analyses in a naturalistic setting
Int J Bipolar Disord, 4 (1), 24
DOI 10.1186/s40345-016-0067-z, PubMed 27858347

Tesli M, Wirgenes KV, Hughes T, Bettella F, Athanasiu L, Hoseth ES, Nerhus M, Lagerberg TV, Steen NE, Agartz I, Melle I, Dieset I, Djurovic S, Andreassen OA (2016)
VRK2 gene expression in schizophrenia, bipolar disorder and healthy controls
Br J Psychiatry, 209 (2), 114-20
DOI 10.1192/bjp.bp.115.161950, PubMed 26941264

Vaskinn A, Sundet K, Østefjells T, Nymo K, Melle I, Ueland T (2016)
Reading Emotions from Body Movement: A Generalized Impairment in Schizophrenia
Front Psychol, 6, 2058
DOI 10.3389/fpsyg.2015.02058, PubMed 26834672

Østefjells T, Melle I, Aminoff SR, Hellvin T, Hagen R, Lagerberg TV, Lystad JU, Røssberg JI (2016)
An exploration of metacognitive beliefs and thought control strategies in bipolar disorder
Compr Psychiatry, 73, 84-92
DOI 10.1016/j.comppsych.2016.11.008, PubMed 27918949

Aas M, Andreassen OA, Aminoff SR, Færden A, Romm KL, Nesvåg R, Berg AO, Simonsen C, Agartz I, Melle I (2016)
A history of childhood trauma is associated with slower improvement rates: Findings from a one-year follow-up study of patients with a first-episode psychosis
BMC Psychiatry, 16, 126
DOI 10.1186/s12888-016-0827-4, PubMed 27146044

Aas M, Henry C, Andreassen OA, Bellivier F, Melle I, Etain B (2016)
The role of childhood trauma in bipolar disorders
Int J Bipolar Disord, 4 (1), 2
DOI 10.1186/s40345-015-0042-0, PubMed 26763504

Aas M, Henry C, Bellivier F, Lajnef M, Gard S, Kahn JP, Lagerberg TV, Aminoff SR, Bjella T, Leboyer M, Andreassen OA, Melle I, Etain B (2016)
Affective lability mediates the association between childhood trauma and suicide attempts, mixed episodes and co-morbid anxiety disorders in bipolar disorders
Psychol Med, 47 (5), 902-912
DOI 10.1017/S0033291716003081, PubMed 27894372

Aas M, Kauppi K, Brandt CL, Tesli M, Kaufmann T, Steen NE, Agartz I, Westlye LT, Andreassen OA, Melle I (2016)
Childhood trauma is associated with increased brain responses to emotionally negative as compared with positive faces in patients with psychotic disorders
Psychol Med, 47 (4), 669-679
DOI 10.1017/S0033291716002762, PubMed 27834153

Publications 2015

Aminoff SR, Tesli M, Bettella F, Aas M, Lagerberg TV, Djurovic S, Andreassen OA, Melle I (2015)
Polygenic risk scores in bipolar disorder subgroups
J Affect Disord, 183, 310-4
DOI 10.1016/j.jad.2015.05.021, PubMed 26047958

Barrett EA, Mork E, Færden A, Nesvåg R, Agartz I, Andreassen OA, Melle I (2015)
The development of insight and its relationship with suicidality over one year follow-up in patients with first episode psychosis
Schizophr Res, 162 (1-3), 97-102
DOI 10.1016/j.schres.2015.01.004, PubMed 25620119

Bauer M, Glenn T, Alda M, Andreassen OA, Angelopoulos E, Ardau R, Baethge C, Bauer R, Baune BT, Bellivier F, Belmaker RH, Berk M, Bjella TD, Bossini L, Bersudsky Y, Wo Cheung EY, Conell J, Del Zompo M, Dodd S, Etain B, Fagiolini A, Frye MA, Fountoulakis KN, Garneau-Fournier J, Gonzalez-Pinto A et al. (2015)
Influence of light exposure during early life on the age of onset of bipolar disorder
J Psychiatr Res, 64, 1-8
DOI 10.1016/j.jpsychires.2015.03.013, PubMed 25862378

Berg AO, Barrett EA, Nerhus M, Büchman C, Simonsen C, Faerden A, Andreassen OA, Melle I (2015)
Psychosis: clinical insight and beliefs in immigrants in their first episode
Early Interv Psychiatry, 12 (2), 185-192
DOI 10.1111/eip.12297, PubMed 26663787

Brandt CL, Doan NT, Tønnesen S, Agartz I, Hugdahl K, Melle I, Andreassen OA, Westlye LT (2015)
Assessing brain structural associations with working-memory related brain patterns in schizophrenia and healthy controls using linked independent component analysis
Neuroimage Clin, 9, 253-63
DOI 10.1016/j.nicl.2015.08.010, PubMed 26509112

Brandt CL, Kaufmann T, Agartz I, Hugdahl K, Jensen J, Ueland T, Haatveit B, Skatun KC, Doan NT, Melle I, Andreassen OA, Westlye LT (2015)
Cognitive Effort and Schizophrenia Modulate Large-Scale Functional Brain Connectivity
Schizophr Bull, 41 (6), 1360-9
DOI 10.1093/schbul/sbv013, PubMed 25731885

Fretland RA, Andersson S, Sundet K, Andreassen OA, Melle I, Vaskinn A (2015)
Theory of mind in schizophrenia: error types and associations with symptoms
Schizophr Res, 162 (1-3), 42-6
DOI 10.1016/j.schres.2015.01.024, PubMed 25623602

Friis S, Melle I, Johannessen JO, Røssberg JI, Barder HE, Evensen JH, Haahr U, Ten Velden Hegelstad W, Joa I, Langeveld J, Larsen TK, Opjordsmoen S, Rund BR, Simonsen E, Vaglum PW, McGlashan TH (2015)
Early Predictors of Ten-Year Course in First-Episode Psychosis
Psychiatr Serv, 67 (4), 438-43
DOI 10.1176/appi.ps.201400558, PubMed 26567932

Haram M, Tesli M, Bettella F, Djurovic S, Andreassen OA, Melle I (2015)
Association between Genetic Variation in the Oxytocin Receptor Gene and Emotional Withdrawal, but not between Oxytocin Pathway Genes and Diagnosis in Psychotic Disorders
Front Hum Neurosci, 9, 9
DOI 10.3389/fnhum.2015.00009, PubMed 25667571

Hartberg CB, Jørgensen KN, Haukvik UK, Westlye LT, Melle I, Andreassen OA, Agartz I (2015)
Lithium treatment and hippocampal subfields and amygdala volumes in bipolar disorder
Bipolar Disord, 17 (5), 496-506
DOI 10.1111/bdi.12295, PubMed 25809287

Haug E, Øie M, Andreassen OA, Bratlien U, Nelson B, Melle I, Møller P (2015)
High levels of anomalous self-experience are associated with longer duration of untreated psychosis
Early Interv Psychiatry, 11 (2), 133-138
DOI 10.1111/eip.12220, PubMed 25589153

Haukvik UK, Hartberg CB, Nerland S, Jørgensen KN, Lange EH, Simonsen C, Nesvåg R, Dale AM, Andreassen OA, Melle I, Agartz I (2015)
No progressive brain changes during a 1-year follow-up of patients with first-episode psychosis
Psychol Med, 46 (3), 589-98
DOI 10.1017/S003329171500210X, PubMed 26526001

Helle S, Ringen PA, Melle I, Larsen TK, Gjestad R, Johnsen E, Lagerberg TV, Andreassen OA, Kroken RA, Joa I, Ten Velden Hegelstad W, Løberg EM (2015)
Cannabis use is associated with 3years earlier onset of schizophrenia spectrum disorder in a naturalistic, multi-site sample (N=1119)
Schizophr Res, 170 (1), 217-21
DOI 10.1016/j.schres.2015.11.027, PubMed 26682958

Hibar DP, Stein JL, Renteria ME, Arias-Vasquez A, Desrivières S, Jahanshad N, Toro R, Wittfeld K, Abramovic L, Andersson M, Aribisala BS, Armstrong NJ, Bernard M, Bohlken MM, Boks MP, Bralten J, Brown AA, Chakravarty MM, Chen Q, Ching CR, Cuellar-Partida G, den Braber A, Giddaluru S, Goldman AL, Grimm O et al. (2015)
Common genetic variants influence human subcortical brain structures
Nature, 520 (7546), 224-9
DOI 10.1038/nature14101, PubMed 25607358

Hope S, Hoseth E, Dieset I, Mørch RH, Aas M, Aukrust P, Djurovic S, Melle I, Ueland T, Agartz I, Ueland T, Westlye LT, Andreassen OA (2015)
Inflammatory markers are associated with general cognitive abilities in schizophrenia and bipolar disorder patients and healthy controls
Schizophr Res, 165 (2-3), 188-94
DOI 10.1016/j.schres.2015.04.004, PubMed 25956633

Hoseth EZ, Westlye LT, Hope S, Dieset I, Aukrust P, Melle I, Haukvik UK, Agartz I, Ueland T, Ueland T, Andreassen OA (2015)
Association between cytokine levels, verbal memory and hippocampus volume in psychotic disorders and healthy controls
Acta Psychiatr Scand, 133 (1), 53-62
DOI 10.1111/acps.12467, PubMed 26189721

Howrigan DP, Simonson MA, Davies G, Harris SE, Tenesa A, Starr JM, Liewald DC, Deary IJ, McRae A, Wright MJ, Montgomery GW, Hansell N, Martin NG, Payton A, Horan M, Ollier WE, Abdellaoui A, Boomsma DI, DeRosse P, Knowles EE, Glahn DC, Djurovic S, Melle I, Andreassen OA, Christoforou A et al. (2015)
Genome-wide autozygosity is associated with lower general cognitive ability
Mol Psychiatry, 21 (6), 837-43
DOI 10.1038/mp.2015.120, PubMed 26390830

Hughes T, Hansson L, Sønderby IE, Athanasiu L, Zuber V, Tesli M, Song J, Hultman CM, Bergen SE, Landén M, Melle I, Andreassen OA, Djurovic S (2015)
A Loss-of-Function Variant in a Minor Isoform of ANK3 Protects Against Bipolar Disorder and Schizophrenia
Biol Psychiatry, 80 (4), 323-330
DOI 10.1016/j.biopsych.2015.09.021, PubMed 26682468

Haatveit B, Vaskinn A, Sundet KS, Jensen J, Andreassen OA, Melle I, Ueland T (2015)
Stability of executive functions in first episode psychosis: One year follow up study
Psychiatry Res, 228 (3), 475-81
DOI 10.1016/j.psychres.2015.05.060, PubMed 26165960

Jørgensen KN, Skjærvø I, Mørch-Johnsen L, Haukvik UK, Lange EH, Melle I, Andreassen OA, Agartz I (2015)
Cigarette smoking is associated with thinner cingulate and insular cortices in patients with severe mental illness
J Psychiatry Neurosci, 40 (4), 241-9
DOI 10.1503/jpn.140163, PubMed 25672482

Kaufmann T, Skåtun KC, Alnæs D, Doan NT, Duff EP, Tønnesen S, Roussos E, Ueland T, Aminoff SR, Lagerberg TV, Agartz I, Melle IS, Smith SM, Andreassen OA, Westlye LT (2015)
Disintegration of Sensorimotor Brain Networks in Schizophrenia
Schizophr Bull, 41 (6), 1326-35
DOI 10.1093/schbul/sbv060, PubMed 25943122

Kvitland LR, Melle I, Aminoff SR, Demmo C, Lagerberg TV, Andreassen OA, Ringen PA (2015)
Continued cannabis use at one year follow up is associated with elevated mood and lower global functioning in bipolar I disorder
BMC Psychiatry, 15, 11
DOI 10.1186/s12888-015-0389-x, PubMed 25651990

Lagerberg TV, Icick R, Andreassen OA, Ringen PA, Etain B, Aas M, Henry C, Bjella TD, Melle I, Bellivier F (2015)
Cannabis use disorder is associated with greater illness severity in tobacco smoking patients with bipolar disorder
J Affect Disord, 190, 286-293
DOI 10.1016/j.jad.2015.10.023, PubMed 26544611

Lee SH, Byrne EM, Hultman CM, Kähler A, Vinkhuyzen AA, Ripke S, Andreassen OA, Frisell T, Gusev A, Hu X, Karlsson R, Mantzioris VX, McGrath JJ, Mehta D, Stahl EA, Zhao Q, Kendler KS, Sullivan PF, Price AL, O'Donovan M, Okada Y, Mowry BJ, Raychaudhuri S, Wray NR, Schizophrenia Working Group of the Psychiatric Genomics Consortium and Rheumatoid Arthritis Consortium International et al. (2015)
New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis
Int J Epidemiol, 44 (5), 1706-21
DOI 10.1093/ije/dyv136, PubMed 26286434

Mellerup E, Andreassen OA, Bennike B, Dam H, Djurovic S, Hansen T, Jorgensen MB, Kessing LV, Koefoed P, Melle I, Mors O, Werge T, Moeller GL (2015)
Combinations of Genetic Data Present in Bipolar Patients, but Absent in Control Persons
PLoS One, 10 (11), e0143432
DOI 10.1371/journal.pone.0143432, PubMed 26587987

Mørch-Johnsen L, Nesvåg R, Faerden A, Haukvik UK, Jørgensen KN, Lange EH, Andreassen OA, Melle I, Agartz I (2015)
Brain structure abnormalities in first-episode psychosis patients with persistent apathy
Schizophr Res, 164 (1-3), 59-64
DOI 10.1016/j.schres.2015.03.001, PubMed 25818626

Nerhus M, Berg AO, Dahl SR, Holvik K, Gardsjord ES, Weibell MA, Bjella TD, Andreassen OA, Melle I (2015)
Vitamin D status in psychotic disorder patients and healthy controls--The influence of ethnic background
Psychiatry Res, 230 (2), 616-21
DOI 10.1016/j.psychres.2015.10.015, PubMed 26500071

Rahm C, Liberg B, Reckless G, Ousdal O, Melle I, Andreassen OA, Agartz I (2015)
Negative symptoms in schizophrenia show association with amygdala volumes and neural activation during affective processing
Acta Neuropsychiatr, 27 (4), 213-20
DOI 10.1017/neu.2015.11, PubMed 25777814

Rund BR, Barder HE, Evensen J, Haahr U, ten Velden Hegelstad W, Joa I, Johannessen JO, Langeveld J, Larsen TK, Melle I, Opjordsmoen S, Røssberg JI, Simonsen E, Sundet K, Vaglum P, McGlashan T, Friis S (2015)
Neurocognition and Duration of Psychosis: A 10-year Follow-up of First-Episode Patients
Schizophr Bull, 42 (1), 87-95
DOI 10.1093/schbul/sbv083, PubMed 26101305

Srinivasan S, Bettella F, Mattingsdal M, Wang Y, Witoelar A, Schork AJ, Thompson WK, Zuber V, Schizophrenia Working Group of the Psychiatric Genomics Consortium, The International Headache Genetics Consortium, Winsvold BS, Zwart JA, Collier DA, Desikan RS, Melle I, Werge T, Dale AM, Djurovic S, Andreassen OA (2015)
Genetic Markers of Human Evolution Are Enriched in Schizophrenia
Biol Psychiatry, 80 (4), 284-292
DOI 10.1016/j.biopsych.2015.10.009, PubMed 26681495

Steen NE, Aas M, Simonsen C, Dieset I, Tesli M, Nerhus M, Gardsjord E, Mørch R, Agartz I, Melle I, Vaskinn A, Spigset O, Andreassen OA (2015)
Serum level of venlafaxine is associated with better memory in psychotic disorders
Schizophr Res, 169 (1-3), 386-392
DOI 10.1016/j.schres.2015.10.021, PubMed 26516101

Steinan MK, Morken G, Lagerberg TV, Melle I, Andreassen OA, Vaaler AE, Scott J (2015)
Delayed sleep phase: An important circadian subtype of sleep disturbance in bipolar disorders
J Affect Disord, 191, 156-63
DOI 10.1016/j.jad.2015.11.025, PubMed 26655861

Steinan MK, Scott J, Lagerberg TV, Melle I, Andreassen OA, Vaaler AE, Morken G (2015)
Sleep problems in bipolar disorders: more than just insomnia
Acta Psychiatr Scand, 133 (5), 368-77
DOI 10.1111/acps.12523, PubMed 26590799

Tesli M, Kauppi K, Bettella F, Brandt CL, Kaufmann T, Espeseth T, Mattingsdal M, Agartz I, Melle I, Djurovic S, Westlye LT, Andreassen OA (2015)
Altered Brain Activation during Emotional Face Processing in Relation to Both Diagnosis and Polygenic Risk of Bipolar Disorder
PLoS One, 10 (7), e0134202
DOI 10.1371/journal.pone.0134202, PubMed 26222050

Trampush JW, Lencz T, Knowles E, Davies G, Guha S, Pe'er I, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, Mukherjee S, DeRosse P, Lundervold A, Steen VM, John M, Espeseth T, Räikkönen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B et al. (2015)
Independent evidence for an association between general cognitive ability and a genetic locus for educational attainment
Am J Med Genet B Neuropsychiatr Genet, 168B (5), 363-73
DOI 10.1002/ajmg.b.32319, PubMed 25951819

van Erp TG, Hibar DP, Rasmussen JM, Glahn DC, Pearlson GD, Andreassen OA, Agartz I, Westlye LT, Haukvik UK, Dale AM, Melle I, Hartberg CB, Gruber O, Kraemer B, Zilles D, Donohoe G, Kelly S, McDonald C, Morris DW, Cannon DM, Corvin A, Machielsen MW, Koenders L, de Haan L, Veltman DJ et al. (2015)
Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium
Mol Psychiatry, 21 (4), 547-53
DOI 10.1038/mp.2015.63, PubMed 26033243

van Erp TG, Hibar DP, Rasmussen JM, Glahn DC, Pearlson GD, Andreassen OA, Agartz I, Westlye LT, Haukvik UK, Dale AM, Melle I, Hartberg CB, Gruber O, Kraemer B, Zilles D, Donohoe G, Kelly S, McDonald C, Morris DW, Cannon DM, Corvin A, Machielsen MW, Koenders L, de Haan L, Veltman DJ et al. (2015)
Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium
Mol Psychiatry, 21 (4), 585
DOI 10.1038/mp.2015.118, PubMed 26283641

Vaskinn A, Hartberg CB, Sundet K, Westlye LT, Andreassen OA, Melle I, Agartz I (2015)
Brain structure characteristics in intellectually superior schizophrenia
Psychiatry Res, 232 (1), 123-9
DOI 10.1016/j.pscychresns.2015.02.005, PubMed 25754688

Vaskinn A, Hartberg CB, Sundet K, Westlye LT, Andreassen OA, Melle I, Agartz I (2015)
To the editors: Reply to Anna R. Docherty
Psychiatry Res, 233 (3), 497
DOI 10.1016/j.pscychresns.2015.07.022, PubMed 26319295

Vaskinn A, Ventura J, Andreassen OA, Melle I, Sundet K (2015)
A social path to functioning in schizophrenia: From social self-efficacy through negative symptoms to social functional capacity
Psychiatry Res, 228 (3), 803-7
DOI 10.1016/j.psychres.2015.05.019, PubMed 26089018

Østefjells T, Melle I, Hagen R, Romm KL, Sönmez N, Andreassen OA, Røssberg JI (2015)
Unhelpful metacognitive beliefs in early psychosis are associated with affective symptoms and childhood social adjustment
Schizophr Res, 169 (1-3), 280-285
DOI 10.1016/j.schres.2015.10.026, PubMed 26519990

Publications 2014

Barder HE, Sundet K, Rund B, Evensen J, Haahr U, Hegelstad W, Joa I, Johannessen JO, Langeveld J, Larsen TK, Melle I, Opjordsmoen S, Rossberg JI, Simonsen E, Vaglum P, McGlashan T, Friis S (2014)
Ten year neurocognitive trajectories in first-episode psychosis (vol 7, pg 643, 2013)
Front. Hum. Neurosci., 8, 319
DOI 10.3389/fnhum.2014.00319

Barder HE, Sundet K, Rund BR, Evensen J, Haahr U, ten Velden Hegelstad W, Joa I, Johannessen JO, Langeveld J, Larsen TK, Melle I, Opjordsmoen S, Røssberg JI, Simonsen E, Vaglum P, McGlashan T, Friis SP (2014)
10 year course of IQ in first-episode psychosis: relationship between duration of psychosis and long-term intellectual trajectories
Psychiatry Res, 225 (3), 515-21
DOI 10.1016/j.psychres.2014.11.054, PubMed 25535007

Bauer M, Glenn T, Alda M, Andreassen OA, Angelopoulos E, Ardau R, Baethge C, Bauer R, Bellivier F, Belmaker RH, Berk M, Bjella TD, Bossini L, Bersudsky Y, Cheung EY, Conell J, Del Zompo M, Dodd S, Etain B, Fagiolini A, Frye MA, Fountoulakis KN, Garneau-Fournier J, González-Pinto A, Harima H et al. (2014)
Relationship between sunlight and the age of onset of bipolar disorder: an international multisite study
J Affect Disord, 167, 104-11
DOI 10.1016/j.jad.2014.05.032, PubMed 24953482

Bauer M, Glenn T, Alda M, Andreassen OA, Angelopoulos E, Ardau R, Baethge C, Bauer R, Bellivier F, Belmaker RH, Berk M, Bjella TD, Bossini L, Bersudsky Y, Cheung EY, Conell J, Del Zompo M, Dodd S, Etain B, Fagiolini A, Frye MA, Fountoulakis KN, Garneau-Fournier J, Gonzalez-Pinto A, Harima H et al. (2014)
Influence of birth cohort on age of onset cluster analysis in bipolar I disorder
Eur Psychiatry, 30 (1), 99-105
DOI 10.1016/j.eurpsy.2014.10.005, PubMed 25498240

Berg AO, Andreassen OA, Aminoff SR, Romm KL, Hauff E, Melle I (2014)
The impact of immigration and visible minority status on psychosis symptom profile
Soc Psychiatry Psychiatr Epidemiol, 49 (11), 1747-57
DOI 10.1007/s00127-014-0897-x, PubMed 24927946

Berg AO, Aas M, Larsson S, Nerhus M, Hauff E, Andreassen OA, Melle I (2014)
Childhood trauma mediates the association between ethnic minority status and more severe hallucinations in psychotic disorder
Psychol Med, 45 (1), 133-42
DOI 10.1017/S0033291714001135, PubMed 25065296

Brandt CL, Eichele T, Melle I, Sundet K, Server A, Agartz I, Hugdahl K, Jensen J, Andreassen OA (2014)
Working memory networks and activation patterns in schizophrenia and bipolar disorder: comparison with healthy controls
Br J Psychiatry, 204, 290-8
DOI 10.1192/bjp.bp.113.129254, PubMed 24434074

Bratlien U, Øie M, Haug E, Møller P, Andreassen OA, Lien L, Melle I (2014)
Environmental factors during adolescence associated with later development of psychotic disorders - a nested case-control study
Psychiatry Res, 215 (3), 579-85
DOI 10.1016/j.psychres.2013.12.048, PubMed 24495574

Dieset I, Haukvik UK, Melle I, Røssberg JI, Ueland T, Hope S, Dale AM, Djurovic S, Aukrust P, Agartz I, Andreassen OA (2014)
Association between altered brain morphology and elevated peripheral endothelial markers--implications for psychotic disorders
Schizophr Res, 161 (2-3), 222-8
DOI 10.1016/j.schres.2014.11.006, PubMed 25433965

Haram M, Tesli M, Dieset I, Steen NE, Røssberg JI, Djurovic S, Andreassen OA, Melle I (2014)
An attempt to identify single nucleotide polymorphisms contributing to possible relationships between personality traits and oxytocin-related genes
Neuropsychobiology, 69 (1), 25-30
DOI 10.1159/000356965, PubMed 24458227

Haug E, Øie M, Andreassen OA, Bratlien U, Nelson B, Aas M, Møller P, Melle I (2014)
Anomalous self-experience and childhood trauma in first-episode schizophrenia
Compr Psychiatry, 56, 35-41
DOI 10.1016/j.comppsych.2014.10.005, PubMed 25458477

Haukvik UK, Westlye LT, Mørch-Johnsen L, Jørgensen KN, Lange EH, Dale AM, Melle I, Andreassen OA, Agartz I (2014)
In vivo hippocampal subfield volumes in schizophrenia and bipolar disorder
Biol Psychiatry, 77 (6), 581-8
DOI 10.1016/j.biopsych.2014.06.020, PubMed 25127742

Kauppi K, Westlye LT, Tesli M, Bettella F, Brandt CL, Mattingsdal M, Ueland T, Espeseth T, Agartz I, Melle I, Djurovic S, Andreassen OA (2014)
Polygenic risk for schizophrenia associated with working memory-related prefrontal brain activation in patients with schizophrenia and healthy controls
Schizophr Bull, 41 (3), 736-43
DOI 10.1093/schbul/sbu152, PubMed 25392519

Kvitland LR, Melle I, Aminoff SR, Lagerberg TV, Andreassen OA, Ringen PA (2014)
Cannabis use in first-treatment bipolar I disorder: relations to clinical characteristics
Early Interv Psychiatry, 10 (1), 36-44
DOI 10.1111/eip.12138, PubMed 24739233

Langeveld J, Bjørkly S, Auestad B, Barder H, Evensen J, Ten Velden Hegelstad W, Joa I, Johannessen JO, Larsen TK, Melle I, Opjordsmoen S, Røssberg JI, Rund BR, Simonsen E, Vaglum P, McGlashan T, Friis S (2014)
Treatment and violent behavior in persons with first episode psychosis during a 10-year prospective follow-up study
Schizophr Res, 156 (2-3), 272-6
DOI 10.1016/j.schres.2014.04.010, PubMed 24837683

Sonmez N, Hagen R, Andreassen OA, Romm KL, Grande M, Jensen LH, Morrison AP, Melle I, Rossberg JI (2014)
Cognitive Behavior Therapy in First-Episode Psychosis With a Focus on Depression, Anxiety, and Self-Esteem
Cogn. Behav. Pract., 21 (1), 43-54

Steen NE, Methlie P, Lorentzen S, Dieset I, Aas M, Nerhus M, Haram M, Agartz I, Melle I, Berg JP, Andreassen OA (2014)
Altered systemic cortisol metabolism in bipolar disorder and schizophrenia spectrum disorders
J Psychiatr Res, 52, 57-62
DOI 10.1016/j.jpsychires.2014.01.017, PubMed 24534618

Sönmez N, Røssberg JI, Evensen J, Barder HE, Haahr U, Ten Velden Hegelstad W, Joa I, Johannessen JO, Langeveld H, Larsen TK, Melle I, Opjordsmoen S, Rund BR, Simonsen E, Vaglum P, McGlashan T, Friis S (2014)
Depressive symptoms in first-episode psychosis: a 10-year follow-up study
Early Interv Psychiatry, 10 (3), 227-33
DOI 10.1111/eip.12163, PubMed 24956976

Tesli M, Espeseth T, Bettella F, Mattingsdal M, Aas M, Melle I, Djurovic S, Andreassen OA (2014)
Polygenic risk score and the psychosis continuum model
Acta Psychiatr Scand, 130 (4), 311-7
DOI 10.1111/acps.12307, PubMed 24961959

Thompson PM, Stein JL, Medland SE, Hibar DP, Vasquez AA, Renteria ME, Toro R, Jahanshad N, Schumann G, Franke B, Wright MJ, Martin NG, Agartz I, Alda M, Alhusaini S, Almasy L, Almeida J, Alpert K, Andreasen NC, Andreassen OA, Apostolova LG, Appel K, Armstrong NJ, Aribisala B, Bastin ME et al. (2014)
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data
Brain Imaging Behav, 8 (2), 153-82
DOI 10.1007/s11682-013-9269-5, PubMed 24399358

Vaskinn A, Ueland T, Melle I, Agartz I, Andreassen OA, Sundet K (2014)
Neurocognitive Decrements are Present in Intellectually Superior Schizophrenia
Front Psychiatry, 5, 45
DOI 10.3389/fpsyt.2014.00045, PubMed 24847284

Wirgenes KV, Tesli M, Inderhaug E, Athanasiu L, Agartz I, Melle I, Hughes T, Andreassen OA, Djurovic S (2014)
ANK3 gene expression in bipolar disorder and schizophrenia
Br J Psychiatry, 205 (3), 244-5
DOI 10.1192/bjp.bp.114.145433, PubMed 24809399

Aas M, Aminoff SR, Vik Lagerberg T, Etain B, Agartz I, Andreassen OA, Melle I (2014)
Affective lability in patients with bipolar disorders is associated with high levels of childhood trauma
Psychiatry Res, 218 (1-2), 252-5
DOI 10.1016/j.psychres.2014.03.046, PubMed 24803185

Aas M, Dazzan P, Mondelli V, Melle I, Murray RM, Pariante CM (2014)
A systematic review of cognitive function in first-episode psychosis, including a discussion on childhood trauma, stress, and inflammation
Front Psychiatry, 4, 182
DOI 10.3389/fpsyt.2013.00182, PubMed 24409157

Aas M, Haukvik UK, Djurovic S, Tesli M, Athanasiu L, Bjella T, Hansson L, Cattaneo A, Agartz I, Andreassen OA, Melle I (2014)
Interplay between childhood trauma and BDNF val66met variants on blood BDNF mRNA levels and on hippocampus subfields volumes in schizophrenia spectrum and bipolar disorders
J Psychiatr Res, 59, 14-21
DOI 10.1016/j.jpsychires.2014.08.011, PubMed 25246365

Aas M, Pedersen G, Henry C, Bjella T, Bellivier F, Leboyer M, Kahn JP, Cohen RF, Gard S, Aminoff SR, Lagerberg TV, Andreassen OA, Melle I, Etain B (2014)
Psychometric properties of the Affective Lability Scale (54 and 18-item version) in patients with bipolar disorder, first-degree relatives, and healthy controls
J Affect Disord, 172, 375-80
DOI 10.1016/j.jad.2014.10.028, PubMed 25451440

Publications 2013

Aminoff SR, Hellvin T, Lagerberg TV, Berg AO, Andreassen OA, Melle I (2013)
Neurocognitive features in subgroups of bipolar disorder
Bipolar Disord, 15 (3), 272-83
DOI 10.1111/bdi.12061, PubMed 23521608

Barder HE, Sundet K, Rund BR, Evensen J, Haahr U, Ten Velden Hegelstad W, Joa I, Johannessen JO, Langeveld H, Larsen TK, Melle I, Opjordsmoen S, Røssberg JI, Simonsen E, Vaglum P, McGlashan T, Friis S (2013)
Neurocognitive development in first episode psychosis 5 years follow-up: associations between illness severity and cognitive course
Schizophr Res, 149 (1-3), 63-9
DOI 10.1016/j.schres.2013.06.016, PubMed 23810121

Barder HE, Sundet K, Rund BR, Evensen J, Haahr U, Ten Velden Hegelstad W, Joa I, Johannessen JO, Langeveld J, Larsen TK, Melle I, Opjordsmoen S, Røssberg JI, Simonsen E, Vaglum P, McGlashan T, Friis S (2013)
Ten year neurocognitive trajectories in first-episode psychosis
Front Hum Neurosci, 7, 643
DOI 10.3389/fnhum.2013.00643, PubMed 24109449

Bergmann O, Haukvik UK, Brown AA, Rimol LM, Hartberg CB, Athanasiu L, Melle I, Djurovic S, Andreassen OA, Dale AM, Agartz I (2013)
ZNF804A and cortical thickness in schizophrenia and bipolar disorder
Psychiatry Res, 212 (2), 154-7
DOI 10.1016/j.pscychresns.2013.01.007, PubMed 23562677

Bourne C, Aydemir Ö, Balanzá-Martínez V, Bora E, Brissos S, Cavanagh JT, Clark L, Cubukcuoglu Z, Dias VV, Dittmann S, Ferrier IN, Fleck DE, Frangou S, Gallagher P, Jones L, Kieseppä T, Martínez-Aran A, Melle I, Moore PB, Mur M, Pfennig A, Raust A, Senturk V, Simonsen C, Smith DJ et al. (2013)
Neuropsychological testing of cognitive impairment in euthymic bipolar disorder: an individual patient data meta-analysis
Acta Psychiatr Scand, 128 (3), 149-62
DOI 10.1111/acps.12133, PubMed 23617548

Bratlien U, Øie M, Haug E, Møller P, Andreassen OA, Lien L, Melle I (2013)
Self-reported symptoms and health service use in adolescence in persons who later develop psychotic disorders: a prospective case-control study
Early Interv Psychiatry, 9 (3), 221-7
DOI 10.1111/eip.12102, PubMed 24224904

Cross-Disorder Group of the Psychiatric Genomics Consortium, Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, Perlis RH, Mowry BJ, Thapar A, Goddard ME, Witte JS, Absher D, Agartz I, Akil H, Amin F, Andreassen OA, Anjorin A, Anney R, Anttila V, Arking DE, Asherson P, Azevedo MH, Backlund L, Badner JA, Bailey AJ et al. (2013)
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
Nat Genet, 45 (9), 984-94
DOI 10.1038/ng.2711, PubMed 23933821

Etain B, Aas M, Andreassen OA, Lorentzen S, Dieset I, Gard S, Kahn JP, Bellivier F, Leboyer M, Melle I, Henry C (2013)
Childhood trauma is associated with severe clinical characteristics of bipolar disorders
J Clin Psychiatry, 74 (10), 991-8
DOI 10.4088/JCP.13m08353, PubMed 24229750

Faerden A, Barrett EA, Nesvåg R, Friis S, Finset A, Marder SR, Ventura J, Andreassen OA, Agartz I, Melle I (2013)
Apathy, poor verbal memory and male gender predict lower psychosocial functioning one year after the first treatment of psychosis
Psychiatry Res, 210 (1), 55-61
DOI 10.1016/j.psychres.2013.02.007, PubMed 23489592

Finseth PI, Sønderby IE, Djurovic S, Agartz I, Malt UF, Melle I, Morken G, Andreassen OA, Vaaler AE, Tesli M (2013)
Association analysis between suicidal behaviour and candidate genes of bipolar disorder and schizophrenia
J Affect Disord, 163, 110-4
DOI 10.1016/j.jad.2013.12.018, PubMed 24461634

Hansen CF, Torgalsbøen AK, Røssberg JI, Romm KL, Andreassen OA, Bell MD, Melle I (2013)
Object relations, reality testing, and social withdrawal in schizophrenia and bipolar disorder
J Nerv Ment Dis, 201 (3), 222-5
DOI 10.1097/NMD.0b013e3182848ae0, PubMed 23407207

Haug E, Øie M, Andreassen OA, Bratlien U, Raballo A, Nelson B, Møller P, Melle I (2013)
Anomalous self-experiences contribute independently to social dysfunction in the early phases of schizophrenia and psychotic bipolar disorder
Compr Psychiatry, 55 (3), 475-82
DOI 10.1016/j.comppsych.2013.11.010, PubMed 24378241

Haukvik UK, McNeil T, Lange EH, Melle I, Dale AM, Andreassen OA, Agartz I (2013)
Pre- and perinatal hypoxia associated with hippocampus/amygdala volume in bipolar disorder
Psychol Med, 44 (5), 975-85
DOI 10.1017/S0033291713001529, PubMed 23803260

Haukvik UK, Rimol LM, Roddey JC, Hartberg CB, Lange EH, Vaskinn A, Melle I, Andreassen OA, Dale A, Agartz I (2013)
Normal birth weight variation is related to cortical morphology across the psychosis spectrum
Schizophr Bull, 40 (2), 410-9
DOI 10.1093/schbul/sbt005, PubMed 23419977

Hellvin T, Sundet K, Aminoff SR, Andreassen OA, Melle I (2013)
Social functioning in first contact mania: clinical and neurocognitive correlates
Compr Psychiatry, 54 (5), 432-8
DOI 10.1016/j.comppsych.2012.12.016, PubMed 23351832

Johansen R, Iversen VC, Melle I, Hestad KA (2013)
Therapeutic alliance in early schizophrenia spectrum disorders: a cross-sectional study
Ann Gen Psychiatry, 12 (1), 14
DOI 10.1186/1744-859X-12-14, PubMed 23656747

Johansen R, Melle I, Iversen VC, Hestad K (2013)
Personality traits, interpersonal problems and therapeutic alliance in early schizophrenia spectrum disorders
Compr Psychiatry, 54 (8), 1169-76
DOI 10.1016/j.comppsych.2013.05.016, PubMed 23856387

Lagerberg TV, Kvitland LR, Aminoff SR, Aas M, Ringen PA, Andreassen OA, Melle I (2013)
Indications of a dose-response relationship between cannabis use and age at onset in bipolar disorder
Psychiatry Res, 215 (1), 101-4
DOI 10.1016/j.psychres.2013.10.029, PubMed 24262665

Lange EH, Nesvåg R, Ringen PA, Hartberg CB, Haukvik UK, Andreassen OA, Melle I, Agartz I (2013)
One year follow-up of alcohol and illicit substance use in first-episode psychosis: does gender matter?
Compr Psychiatry, 55 (2), 274-82
DOI 10.1016/j.comppsych.2013.08.018, PubMed 24262129

Larsson S, Aas M, Klungsøyr O, Agartz I, Mork E, Steen NE, Barrett EA, Lagerberg TV, Røssberg JI, Melle I, Andreassen OA, Lorentzen S (2013)
Patterns of childhood adverse events are associated with clinical characteristics of bipolar disorder
BMC Psychiatry, 13, 97
DOI 10.1186/1471-244X-13-97, PubMed 23522391

Lencz T, Knowles E, Davies G, Guha S, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, Mukherjee S, DeRosse P, Lundervold A, Steen VM, John M, Espeseth T, Räikkönen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Ikeda M, Roussos P et al. (2013)
Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: a report from the Cognitive Genomics consorTium (COGENT)
Mol Psychiatry, 19 (2), 168-74
DOI 10.1038/mp.2013.166, PubMed 24342994

Melle I (2013)
The Breivik case and what psychiatrists can learn from it
World Psychiatry, 12 (1), 16-21
DOI 10.1002/wps.20002, PubMed 23471788

Melle I (2013)
History of depression and previous suicide attempt predict increased risk of suicide attempt following diagnosis of first-episode psychosis
Evid Based Ment Health, 16 (3), 67
DOI 10.1136/eb-2013-101362, PubMed 23839291

Mork E, Walby FA, Harkavy-Friedman JM, Barrett EA, Steen NE, Lorentzen S, Andreassen OA, Melle I, Mehlum L (2013)
Clinical characteristics in schizophrenia patients with or without suicide attempts and non-suicidal self-harm--a cross-sectional study
BMC Psychiatry, 13, 255
DOI 10.1186/1471-244X-13-255, PubMed 24106884

Nerhus M, Berg AO, Haram M, Kvitland LR, Andreassen OA, Melle I (2013)
Migrant background and ethnic minority status as predictors for duration of untreated psychosis
Early Interv Psychiatry, 9 (1), 61-5
DOI 10.1111/eip.12106, PubMed 24225002

Nesvåg R, Schaer M, Haukvik UK, Westlye LT, Rimol LM, Lange EH, Hartberg CB, Ottet MC, Melle I, Andreassen OA, Jönsson EG, Agartz I, Eliez S (2013)
Reduced brain cortical folding in schizophrenia revealed in two independent samples
Schizophr Res, 152 (2-3), 333-8
DOI 10.1016/j.schres.2013.11.032, PubMed 24365403

Schoeyen HK, Melle I, Sundet K, Aminoff SR, Hellvin T, Auestad BH, Morken G, Andreassen OA (2013)
Occupational outcome in bipolar disorder is not predicted by premorbid functioning and intelligence
Bipolar Disord, 15 (3), 294-305
DOI 10.1111/bdi.12056, PubMed 23527993

Sönmez N, Romm KL, Andreasssen OA, Melle I, Røssberg JI (2013)
Depressive symptoms in first episode psychosis: a one-year follow-up study
BMC Psychiatry, 13, 106
DOI 10.1186/1471-244X-13-106, PubMed 23560591

ten Velden Hegelstad W, Joa I, Barder H, Evensen J, Haahr U, Johannessen JO, Langeveld J, Melle I, Opjordsmoen S, Røssberg JI, Rund BR, Simonsen E, Vaglum P, McGlashan T, Friis S, Larsen TK (2013)
Variation in duration of untreated psychosis in an 18-year perspective
Early Interv Psychiatry, 8 (4), 323-31
DOI 10.1111/eip.12057, PubMed 23773272

Tesli M, Egeland R, Sønderby IE, Haukvik UK, Bettella F, Hibar DP, Thompson PM, Rimol LM, Melle I, Agartz I, Djurovic S, Andreassen OA (2013)
No evidence for association between bipolar disorder risk gene variants and brain structural phenotypes
J Affect Disord, 151 (1), 291-7
DOI 10.1016/j.jad.2013.06.008, PubMed 23820096

Tesli M, Skatun KC, Ousdal OT, Brown AA, Thoresen C, Agartz I, Melle I, Djurovic S, Jensen J, Andreassen OA (2013)
CACNA1C risk variant and amygdala activity in bipolar disorder, schizophrenia and healthy controls
PLoS One, 8 (2), e56970
DOI 10.1371/journal.pone.0056970, PubMed 23437284

Vaskinn A, Sundet K, Ueland T, Agartz I, Melle I, Andreassen OA (2013)
Social cognition and clinical insight in schizophrenia and bipolar disorder
J Nerv Ment Dis, 201 (6), 445-51
DOI 10.1097/NMD.0b013e31829480c8, PubMed 23686158

Welander-Vatn A, Jensen J, Otnaess MK, Agartz I, Server A, Melle I, Andreassen OA (2013)
The neural correlates of cognitive control in bipolar I disorder: an fMRI study of medial frontal cortex activation during a Go/No-go task
Neurosci Lett, 549, 51-6
DOI 10.1016/j.neulet.2013.06.010, PubMed 23778236

Aas M, Etain B, Bellivier F, Henry C, Lagerberg T, Ringen A, Agartz I, Gard S, Kahn JP, Leboyer M, Andreassen OA, Melle I (2013)
Additive effects of childhood abuse and cannabis abuse on clinical expressions of bipolar disorders
Psychol Med, 44 (8), 1653-62
DOI 10.1017/S0033291713002316, PubMed 24028906

Aas M, Haukvik UK, Djurovic S, Bergmann Ø, Athanasiu L, Tesli MS, Hellvin T, Steen NE, Agartz I, Lorentzen S, Sundet K, Andreassen OA, Melle I (2013)
BDNF val66met modulates the association between childhood trauma, cognitive and brain abnormalities in psychoses
Prog Neuropsychopharmacol Biol Psychiatry, 46, 181-8
DOI 10.1016/j.pnpbp.2013.07.008, PubMed 23876786

Publications 2012

Aminoff SR, Jensen J, Lagerberg TV, Hellvin T, Sundet K, Andreassen OA, Melle I (2012)
An association between affective lability and executive functioning in bipolar disorder
Psychiatry Res, 198 (1), 58-61
DOI 10.1016/j.psychres.2011.12.044, PubMed 22405635

Athanasiu L, Brown AA, Birkenaes AB, Mattingsdal M, Agartz I, Melle I, Steen VM, Andreassen OA, Djurovic S (2012)
Genome-wide association study identifies genetic loci associated with body mass index and high density lipoprotein-cholesterol levels during psychopharmacological treatment - a cross-sectional naturalistic study
Psychiatry Res, 197 (3), 327-36
DOI 10.1016/j.psychres.2011.12.036, PubMed 22417934

Bakken TE, Roddey JC, Djurovic S, Akshoomoff N, Amaral DG, Bloss CS, Casey BJ, Chang L, Ernst TM, Gruen JR, Jernigan TL, Kaufmann WE, Kenet T, Kennedy DN, Kuperman JM, Murray SS, Sowell ER, Rimol LM, Mattingsdal M, Melle I, Agartz I, Andreassen OA, Schork NJ, Dale AM, Alzheimer's Disease Neuroimaging Initiative et al. (2012)
Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans
Proc Natl Acad Sci U S A, 109 (10), 3985-90
DOI 10.1073/pnas.1105829109, PubMed 22343285

Bauer M, Glenn T, Alda M, Andreassen OA, Ardau R, Bellivier F, Berk M, Bjella TD, Bossini L, Del Zompo M, Dodd S, Fagiolini A, Frye MA, Gonzalez-Pinto A, Henry C, Kapczinski F, Kliwicki S, König B, Kunz M, Lafer B, Lopez-Jaramillo C, Manchia M, Marsh W, Martinez-Cengotitabengoa M, Melle I et al. (2012)
Impact of sunlight on the age of onset of bipolar disorder
Bipolar Disord, 14 (6), 654-63
DOI 10.1111/j.1399-5618.2012.01025.x, PubMed 22612720

Bratlien U, Øie M, Lien L, Agartz I, Lie Romm K, Vaskinn A, Ueland T, Andreassen OA, Melle I (2012)
Social dysfunction in first-episode psychosis and relations to neurocognition, duration of untreated psychosis and clinical symptoms
Psychiatry Res, 207 (1-2), 33-9
DOI 10.1016/j.psychres.2012.10.010, PubMed 23153893

Brown AA, Jensen J, Nikolova YS, Djurovic S, Agartz I, Server A, Ferrell RE, Manuck SB, Mattingsdal M, Melle I, Hariri AR, Frigessi A, Andreassen OA (2012)
Genetic variants affecting the neural processing of human facial expressions: evidence using a genome-wide functional imaging approach
Transl Psychiatry, 2 (7), e143
DOI 10.1038/tp.2012.67, PubMed 22828495

Dieset I, Djurovic S, Tesli M, Hope S, Mattingsdal M, Michelsen A, Joa I, Larsen TK, Agartz I, Melle I, Røssberg JI, Aukrust P, Andreassen OA, Ueland T (2012)
Up-regulation of NOTCH4 gene expression in bipolar disorder
Am J Psychiatry, 169 (12), 1292-300
DOI 10.1176/appi.ajp.2012.11091431, PubMed 23212060

Dieset I, Hope S, Ueland T, Bjella T, Agartz I, Melle I, Aukrust P, Røssberg JI, Andreassen OA (2012)
Cardiovascular risk factors during second generation antipsychotic treatment are associated with increased C-reactive protein
Schizophr Res, 140 (1-3), 169-74
DOI 10.1016/j.schres.2012.06.040, PubMed 22817875

Evensen J, Røssberg JI, Barder H, Haahr U, Hegelstad Wt, Joa I, Johannessen JO, Larsen TK, Melle I, Opjordsmoen S, Rund BR, Simonsen E, Sundet K, Vaglum P, Friis S, McGlashan T (2012)
Apathy in first episode psychosis patients: a ten year longitudinal follow-up study
Schizophr Res, 136 (1-3), 19-24
DOI 10.1016/j.schres.2011.12.019, PubMed 22285655

Evensen J, Røssberg JI, Barder H, Haahr U, Hegelstad WT, Joa I, Johannessen JO, Larsen TK, Melle I, Opjordsmoen S, Rund BR, Simonsen E, Vaglum P, McGlashan T, Friis S (2012)
Flat affect and social functioning: a 10 year follow-up study of first episode psychosis patients
Schizophr Res, 139 (1-3), 99-104
DOI 10.1016/j.schres.2012.04.019, PubMed 22627124

Friis S, Barder H, Evensen JH, Haahr U, Hegelstad WT, Joa I, Johannessen JO, Langeveld J, Larsen TK, Melle I, Opjordsmoen S, Rund BR, Røssberg JI, Simonsen E, Sundet K, Vaglum P, McGlashan T (2012)
The TIPS study and bias: replies to Dr Amos
Aust N Z J Psychiatry, 46 (9), 905-7
DOI 10.1177/0004867412451344, PubMed 22956571

Hansen CF, Torgalsbøen AK, Røssberg JI, Andreassen OA, Bell MD, Melle I (2012)
Object relations and reality testing in schizophrenia, bipolar disorders, and healthy controls: differences in profiles and clinical correlates
Compr Psychiatry, 53 (8), 1200-7
DOI 10.1016/j.comppsych.2012.04.003, PubMed 22578986

Haug E, Lien L, Raballo A, Bratlien U, Oie M, Andreassen OA, Melle I, Møller P (2012)
Selective aggregation of self-disorders in first-treatment DSM-IV schizophrenia spectrum disorders
J Nerv Ment Dis, 200 (7), 632-6
DOI 10.1097/NMD.0b013e31825bfd6f, PubMed 22759943

Hegelstad WT, Larsen TK, Auestad B, Evensen J, Haahr U, Joa I, Johannesen JO, Langeveld J, Melle I, Opjordsmoen S, Rossberg JI, Rund BR, Simonsen E, Sundet K, Vaglum P, Friis S, McGlashan T (2012)
Long-term follow-up of the TIPS early detection in psychosis study: effects on 10-year outcome
Am J Psychiatry, 169 (4), 374-80
DOI 10.1176/appi.ajp.2011.11030459, PubMed 22407080

Hellvin T, Sundet K, Simonsen C, Aminoff SR, Lagerberg TV, Andreassen OA, Melle I (2012)
Neurocognitive functioning in patients recently diagnosed with bipolar disorder
Bipolar Disord, 14 (3), 227-38
DOI 10.1111/j.1399-5618.2012.01004.x, PubMed 22548896

Holmén A, Juuhl-Langseth M, Thormodsen R, Sundet K, Melle I, Rund BR (2012)
Executive function tests in early-onset psychosis: which one to choose?
Scand J Psychol, 53 (3), 200-5
DOI 10.1111/j.1467-9450.2012.00940.x, PubMed 22416819

Holmén A, Juuhl-Langseth M, Thormodsen R, Ueland T, Agartz I, Sundet K, Andreassen OA, Rund BR, Melle I (2012)
Executive function in early- and adult onset schizophrenia
Schizophr Res, 142 (1-3), 177-82
DOI 10.1016/j.schres.2012.10.006, PubMed 23102692

Haahr U, Simonsen E, Røssberg JI, Johannessen JO, Larsen TK, Melle I, Opjordsmoen S, Rund BR, Vaglum P, Friis S, McGlashan T (2012)
Patient satisfaction with treatment in first-episode psychosis
Nord J Psychiatry, 66 (5), 329-35
DOI 10.3109/08039488.2011.644808, PubMed 22250962

Jönsson EG, Saetre P, Nyholm H, Djurovic S, Melle I, Andreassen OA, Skjødt C, Thygesen JH, Werge T, Hall H, Agartz I, Terenius L (2012)
Lack of association between the regulator of G-protein signaling 4 (RGS4) rs951436 polymorphism and schizophrenia
Psychiatr Genet, 22 (5), 263-4
DOI 10.1097/YPG.0b013e32834f3558, PubMed 22157635

Kähler AK, Rimol LM, Brown AA, Djurovic S, Hartberg CB, Melle I, Dale AM, Andreassen OA, Agartz I (2012)
Effect of DISC1 SNPs on brain structure in healthy controls and patients with a history of psychosis
Am J Med Genet B Neuropsychiatr Genet, 159B (6), 722-30
DOI 10.1002/ajmg.b.32076, PubMed 22815203

Langeveld J, Andreassen OA, Auestad B, Færden A, Hauge LJ, Joa I, Johannessen JO, Melle I, Rund BR, Røssberg JI, Simonsen E, Vaglum P, Larsen TK (2012)
Is there an optimal factor structure of the Positive and Negative Syndrome Scale in patients with first-episode psychosis?
Scand J Psychol, 54 (2), 160-5
DOI 10.1111/sjop.12017, PubMed 23252448

Langeveld J, Joa I, Friis S, ten Velden Hegelstad W, Melle I, Johannessen JO, Opjordsmoen S, Simonsen E, Vaglum P, Auestad B, McGlashan T, Larsen TK (2012)
A comparison of adolescent- and adult-onset first-episode, non-affective psychosis: 2-year follow-up
Eur Arch Psychiatry Clin Neurosci, 262 (7), 599-605
DOI 10.1007/s00406-012-0308-9, PubMed 22441715

Larsson S, Andreassen OA, Aas M, Røssberg JI, Mork E, Steen NE, Barrett EA, Lagerberg TV, Peleikis D, Agartz I, Melle I, Lorentzen S (2012)
High prevalence of childhood trauma in patients with schizophrenia spectrum and affective disorder
Compr Psychiatry, 54 (2), 123-7
DOI 10.1016/j.comppsych.2012.06.009, PubMed 22901835

Lindholm Carlström E, Saetre P, Rosengren A, Thygesen JH, Djurovic S, Melle I, Andreassen OA, Werge T, Agartz I, Hall H, Terenius L, Jönsson EG (2012)
Association between a genetic variant in the serotonin transporter gene (SLC6A4) and suicidal behavior in patients with schizophrenia
Behav Brain Funct, 8, 24
DOI 10.1186/1744-9081-8-24, PubMed 22594806

Mattingsdal M, Brown AA, Djurovic S, Sønderby IE, Server A, Melle I, Agartz I, Hovig E, Jensen J, Andreassen OA (2012)
Pathway analysis of genetic markers associated with a functional MRI faces paradigm implicates polymorphisms in calcium responsive pathways
Neuroimage, 70, 143-9
DOI 10.1016/j.neuroimage.2012.12.035, PubMed 23274185

Melle I, Barrett EA (2012)
Insight and suicidal behavior in first-episode schizophrenia
Expert Rev Neurother, 12 (3), 353-9
DOI 10.1586/ern.11.191, PubMed 22364334

Mellerup E, Andreassen O, Bennike B, Dam H, Djurovic S, Hansen T, Melle I, Møller GL, Mors O, Koefoed P (2012)
Connection between genetic and clinical data in bipolar disorder
PLoS One, 7 (9), e44623
DOI 10.1371/journal.pone.0044623, PubMed 23028568

Mork E, Mehlum L, Barrett EA, Agartz I, Harkavy-Friedman JM, Lorentzen S, Melle I, Andreassen OA, Walby FA (2012)
Self-harm in patients with schizophrenia spectrum disorders
Arch Suicide Res, 16 (2), 111-23
DOI 10.1080/13811118.2012.667328, PubMed 22551042

Ousdal OT, Anand Brown A, Jensen J, Nakstad PH, Melle I, Agartz I, Djurovic S, Bogdan R, Hariri AR, Andreassen OA (2012)
Associations between variants near a monoaminergic pathways gene (PHOX2B) and amygdala reactivity: a genome-wide functional imaging study
Twin Res Hum Genet, 15 (3), 273-85
DOI 10.1017/thg.2012.5, PubMed 22856363

Rimol LM, Nesvåg R, Hagler DJ, Bergmann O, Fennema-Notestine C, Hartberg CB, Haukvik UK, Lange E, Pung CJ, Server A, Melle I, Andreassen OA, Agartz I, Dale AM (2012)
Cortical volume, surface area, and thickness in schizophrenia and bipolar disorder
Biol Psychiatry, 71 (6), 552-60
DOI 10.1016/j.biopsych.2011.11.026, PubMed 22281121

Ringen PA, Melle I, Berg AO, Agartz I, Spigset O, Simonsen C, Sundet K, Andreassen OA (2012)
Cannabis use and premorbid functioning as predictors of poorer neurocognition in schizophrenia spectrum disorder
Schizophr Res, 143 (1), 84-9
DOI 10.1016/j.schres.2012.10.021, PubMed 23178107

Stein JL, Medland SE, Vasquez AA, Hibar DP, Senstad RE, Winkler AM, Toro R, Appel K, Bartecek R, Bergmann Ø, Bernard M, Brown AA, Cannon DM, Chakravarty MM, Christoforou A, Domin M, Grimm O, Hollinshead M, Holmes AJ, Homuth G, Hottenga JJ, Langan C, Lopez LM, Hansell NK, Hwang KS et al. (2012)
Identification of common variants associated with human hippocampal and intracranial volumes
Nat Genet, 44 (5), 552-61
DOI 10.1038/ng.2250, PubMed 22504417

Steinberg S, de Jong S, Mattheisen M, Costas J, Demontis D, Jamain S, Pietiläinen OP, Lin K, Papiol S, Huttenlocher J, Sigurdsson E, Vassos E, Giegling I, Breuer R, Fraser G, Walker N, Melle I, Djurovic S, Agartz I, Tuulio-Henriksson A, Suvisaari J, Lönnqvist J, Paunio T, Olsen L, Hansen T et al. (2012)
Common variant at 16p11.2 conferring risk of psychosis
Mol Psychiatry, 19 (1), 108-14
DOI 10.1038/mp.2012.157, PubMed 23164818

Straand T, Melle I, Gjerden P (2012)
User surveys in psychiatry in the 1950s
Tidsskr Nor Laegeforen, 132 (5), 543-6
DOI 10.4045/tidsskr.11.0671, PubMed 22398775

Tandberg M, Sundet K, Andreassen OA, Melle I, Ueland T (2012)
Occupational functioning, symptoms and neurocognition in patients with psychotic disorders: investigating subgroups based on social security status
Soc Psychiatry Psychiatr Epidemiol, 48 (6), 863-74
DOI 10.1007/s00127-012-0598-2, PubMed 23064396

Tandberg M, Ueland T, Andreassen OA, Sundet K, Melle I (2012)
Factors associated with occupational and academic status in patients with first-episode psychosis with a particular focus on neurocognition
Soc Psychiatry Psychiatr Epidemiol, 47 (11), 1763-73
DOI 10.1007/s00127-012-0477-x, PubMed 22310699

Ten Velden Hegelstad W, Haahr U, Larsen TK, Auestad B, Barder H, Evensen J, Joa I, Johannessen JO, Langeveld J, Melle I, Opjordsmoen S, Rossberg JI, Rund BR, Simonsen E, Vaglum P, McGlashan T, Friis S (2012)
Early detection, early symptom progression and symptomatic remission after ten years in a first episode of psychosis study
Schizophr Res, 143 (2-3), 337-43
DOI 10.1016/j.schres.2012.10.027, PubMed 23219862

Vassos E, Steinberg S, Cichon S, Breen G, Sigurdsson E, Andreassen OA, Djurovic S, Morken G, Grigoroiu-Serbanescu M, Diaconu CC, Czerski PM, Hauser J, Babadjanova G, Abramova LI, Mühleisen TW, Nöthen MM, Rietschel M, McGuffin P, St Clair D, Gustafsson O, Melle I, Pietiläinen OP, Ruggeri M, Tosato S, Werge T et al. (2012)
Replication study and meta-analysis in European samples supports association of the 3p21.1 locus with bipolar disorder
Biol Psychiatry, 72 (8), 645-50
DOI 10.1016/j.biopsych.2012.02.040, PubMed 22560537

Wirgenes KV, Sønderby IE, Haukvik UK, Mattingsdal M, Tesli M, Athanasiu L, Sundet K, Røssberg JI, Dale AM, Brown AA, Agartz I, Melle I, Djurovic S, Andreassen OA (2012)
TCF4 sequence variants and mRNA levels are associated with neurodevelopmental characteristics in psychotic disorders
Transl Psychiatry, 2 (5), e112
DOI 10.1038/tp.2012.39, PubMed 22832956

Aas M, Steen NE, Agartz I, Aminoff SR, Lorentzen S, Sundet K, Andreassen OA, Melle I (2012)
Is cognitive impairment following early life stress in severe mental disorders based on specific or general cognitive functioning?
Psychiatry Res, 198 (3), 495-500
DOI 10.1016/j.psychres.2011.12.045, PubMed 22472845

Publications 2011

Agartz I, Brown AA, Rimol LM, Hartberg CB, Dale AM, Melle I, Djurovic S, Andreassen OA (2011)
Common sequence variants in the major histocompatibility complex region associate with cerebral ventricular size in schizophrenia
Biol Psychiatry, 70 (7), 696-8
DOI 10.1016/j.biopsych.2011.02.034, PubMed 21514568

Bakken TE, Bloss CS, Roddey JC, Joyner AH, Rimol LM, Djurovic S, Melle I, Sundet K, Agartz I, Andreassen OA, Dale AM, Schork NJ (2011)
Association of genetic variants on 15q12 with cortical thickness and cognition in schizophrenia
Arch Gen Psychiatry, 68 (8), 781-90
DOI 10.1001/archgenpsychiatry.2011.81, PubMed 21810643

Berg AO, Melle I, Rossberg JI, Romm KL, Larsson S, Lagerberg TV, Andreassen OA, Hauff E (2011)
Perceived discrimination is associated with severity of positive and depression/anxiety symptoms in immigrants with psychosis: a cross-sectional study
BMC Psychiatry, 11, 77
DOI 10.1186/1471-244X-11-77, PubMed 21548949

Bolstad A, Andreassen OA, Røssberg JI, Agartz I, Melle I, Tanum L (2011)
Previous hospital admissions and disease severity predict the use of antipsychotic combination treatment in patients with schizophrenia
BMC Psychiatry, 11, 126
DOI 10.1186/1471-244X-11-126, PubMed 21812996

Caprini S, Saetre P, Melle I, Djurovic S, Andreassen OA, Skjødt C, Duong L, Werge T, Hall H, Agartz I, Terenius L, Jönsson EG (2011)
Lack of association between two dopamine D2 receptor gene polymorphisms and schizophrenia
Psychiatr Genet, 21 (4), 214-5
DOI 10.1097/YPG.0b013e328341e020, PubMed 21712758

Evensen J, Røssberg JI, Haahr U, ten Velden Hegelstad W, Joa I, Johannessen JO, Langeveld H, Larsen TK, Melle I, Opjordsmoen S, Rund BR, Simonsen E, Sundet K, Vaglum P, Friis S, McGlashan T (2011)
Contrasting monosymptomatic patients with hallucinations and delusions in first-episode psychosis patients: a five-year longitudinal follow-up study
Psychopathology, 44 (2), 90-7
DOI 10.1159/000319789, PubMed 21228615

Hansen T, Ingason A, Djurovic S, Melle I, Fenger M, Gustafsson O, Jakobsen KD, Rasmussen HB, Tosato S, Rietschel M, Frank J, Owen M, Bonetto C, Suvisaari J, Thygesen JH, Pétursson H, Lönnqvist J, Sigurdsson E, Giegling I, Craddock N, O'Donovan MC, Ruggeri M, Cichon S, Ophoff RA, Pietiläinen O et al. (2011)
At-risk variant in TCF7L2 for type II diabetes increases risk of schizophrenia
Biol Psychiatry, 70 (1), 59-63
DOI 10.1016/j.biopsych.2011.01.031, PubMed 21414605

Hartberg CB, Sundet K, Rimol LM, Haukvik UK, Lange EH, Nesvåg R, Dale AM, Melle I, Andreassen OA, Agartz I (2011)
Brain cortical thickness and surface area correlates of neurocognitive performance in patients with schizophrenia, bipolar disorder, and healthy adults
J Int Neuropsychol Soc, 17 (6), 1080-93
DOI 10.1017/S1355617711001081, PubMed 22013998

Hartberg CB, Sundet K, Rimol LM, Haukvik UK, Lange EH, Nesvåg R, Melle I, Andreassen OA, Agartz I (2011)
Subcortical brain volumes relate to neurocognition in schizophrenia and bipolar disorder and healthy controls
Prog Neuropsychopharmacol Biol Psychiatry, 35 (4), 1122-30
DOI 10.1016/j.pnpbp.2011.03.014, PubMed 21457744

Haug E, Melle I, Andreassen OA, Raballo A, Bratlien U, Øie M, Lien L, Møller P (2011)
The association between anomalous self-experience and suicidality in first-episode schizophrenia seems mediated by depression
Compr Psychiatry, 53 (5), 456-60
DOI 10.1016/j.comppsych.2011.07.005, PubMed 21871617

Haug E, Øie M, Melle I, Andreassen OA, Raballo A, Bratlien U, Lien L, Møller P (2011)
The association between self-disorders and neurocognitive dysfunction in schizophrenia
Schizophr Res, 135 (1-3), 79-83
DOI 10.1016/j.schres.2011.11.015, PubMed 22137461

Hope S, Dieset I, Agartz I, Steen NE, Ueland T, Melle I, Aukrust P, Andreassen OA (2011)
Affective symptoms are associated with markers of inflammation and immune activation in bipolar disorders but not in schizophrenia
J Psychiatr Res, 45 (12), 1608-16
DOI 10.1016/j.jpsychires.2011.08.003, PubMed 21889167

Håvik B, Le Hellard S, Rietschel M, Lybæk H, Djurovic S, Mattheisen M, Mühleisen TW, Degenhardt F, Priebe L, Maier W, Breuer R, Schulze TG, Agartz I, Melle I, Hansen T, Bramham CR, Nöthen MM, Stevens B, Werge T, Andreassen OA, Cichon S, Steen VM (2011)
The complement control-related genes CSMD1 and CSMD2 associate to schizophrenia
Biol Psychiatry, 70 (1), 35-42
DOI 10.1016/j.biopsych.2011.01.030, PubMed 21439553

Johansen R, Hestad K, Iversen VC, Agartz I, Sundet K, Andreassen OA, Melle I (2011)
Cognitive and clinical factors are associated with service engagement in early-phase schizophrenia spectrum disorders
J Nerv Ment Dis, 199 (3), 176-82
DOI 10.1097/NMD.0b013e31820bc2f9, PubMed 21346488

Koefoed P, Andreassen OA, Bennike B, Dam H, Djurovic S, Hansen T, Jorgensen MB, Kessing LV, Melle I, Møller GL, Mors O, Werge T, Mellerup E (2011)
Combinations of SNPs related to signal transduction in bipolar disorder
PLoS One, 6 (8), e23812
DOI 10.1371/journal.pone.0023812, PubMed 21897858

Lagerberg TV, Sundet K, Aminoff SR, Berg AO, Ringen PA, Andreassen OA, Melle I (2011)
Excessive cannabis use is associated with earlier age at onset in bipolar disorder
Eur Arch Psychiatry Clin Neurosci, 261 (6), 397-405
DOI 10.1007/s00406-011-0188-4, PubMed 21267743

LeBlanc M, Kulle B, Sundet K, Agartz I, Melle I, Djurovic S, Frigessi A, Andreassen OA (2011)
Genome-wide study identifies PTPRO and WDR72 and FOXQ1-SUMO1P1 interaction associated with neurocognitive function
J Psychiatr Res, 46 (2), 271-8
DOI 10.1016/j.jpsychires.2011.11.001, PubMed 22126837

Møller P, Haug E, Raballo A, Parnas J, Melle I (2011)
Examination of anomalous self-experience in first-episode psychosis: interrater reliability
Psychopathology, 44 (6), 386-90
DOI 10.1159/000325173, PubMed 21847006

Olsen L, Hansen T, Djurovic S, Haastrup E, Albrecthsen A, Hoeffding LK, Secher A, Gustafsson O, Jakobsen KD, Nielsen FC, Ullum H, Morken G, Agartz I, Melle I, Gether U, Andreassen OA, Werge T (2011)
Copy number variations in affective disorders and meta-analysis
Psychiatr Genet, 21 (6), 319-22
DOI 10.1097/YPG.0b013e3283463deb, PubMed 21451435

Pers TH, Hansen NT, Lage K, Koefoed P, Dworzynski P, Miller ML, Flint TJ, Mellerup E, Dam H, Andreassen OA, Djurovic S, Melle I, Børglum AD, Werge T, Purcell S, Ferreira MA, Kouskoumvekaki I, Workman CT, Hansen T, Mors O, Brunak S (2011)
Meta-analysis of heterogeneous data sources for genome-scale identification of risk genes in complex phenotypes
Genet Epidemiol, 35 (5), 318-32
DOI 10.1002/gepi.20580, PubMed 21484861

Romm KL, Melle I, Thoresen C, Andreassen OA, Rossberg JI (2011)
Severe social anxiety in early psychosis is associated with poor premorbid functioning, depression, and reduced quality of life
Compr Psychiatry, 53 (5), 434-40
DOI 10.1016/j.comppsych.2011.06.002, PubMed 21821242

Romm KL, Rossberg JI, Hansen CF, Haug E, Andreassen OA, Melle I (2011)
Self-esteem is associated with premorbid adjustment and positive psychotic symptoms in early psychosis
BMC Psychiatry, 11, 136
DOI 10.1186/1471-244X-11-136, PubMed 21854599

Schoeyen HK, Vaaler AE, Auestad BH, Malt UF, Melle I, Andreassen OA, Morken G (2011)
Despite clinical differences, bipolar disorder patients from acute wards and outpatient clinics have similar educational and disability levels compared to the general population
J Affect Disord, 132 (1-2), 209-15
DOI 10.1016/j.jad.2011.02.025, PubMed 21440307

Steen NE, Lorentzen S, Barrett EA, Lagerberg TV, Hope S, Larsson S, Berg AO, Agartz I, Melle I, Berg JP, Andreassen OA (2011)
Sex-specific cortisol levels in bipolar disorder and schizophrenia during mental challenge--relationship to clinical characteristics and medication
Prog Neuropsychopharmacol Biol Psychiatry, 35 (4), 1100-7
DOI 10.1016/j.pnpbp.2011.03.008, PubMed 21420462

Steen NE, Methlie P, Lorentzen S, Hope S, Barrett EA, Larsson S, Mork E, Almås B, Løvås K, Agartz I, Melle I, Berg JP, Andreassen OA (2011)
Increased systemic cortisol metabolism in patients with schizophrenia and bipolar disorder: a mechanism for increased stress vulnerability?
J Clin Psychiatry, 72 (11), 1515-21
DOI 10.4088/JCP.10m06068yel, PubMed 21367348

Steinberg S, de Jong S, Irish Schizophrenia Genomics Consortium, Andreassen OA, Werge T, Børglum AD, Mors O, Mortensen PB, Gustafsson O, Costas J, Pietiläinen OP, Demontis D, Papiol S, Huttenlocher J, Mattheisen M, Breuer R, Vassos E, Giegling I, Fraser G, Walker N, Tuulio-Henriksson A, Suvisaari J, Lönnqvist J, Paunio T, Agartz I et al. (2011)
Common variants at VRK2 and TCF4 conferring risk of schizophrenia
Hum Mol Genet, 20 (20), 4076-81
DOI 10.1093/hmg/ddr325, PubMed 21791550

Tandberg M, Ueland T, Sundet K, Haahr U, Joa I, Johannessen JO, Larsen TK, Opjordsmoen S, Rund BR, Røssberg JI, Simonsen E, Vaglum P, Melle I, Friis S, McGlashan T (2011)
Neurocognition and occupational functioning in patients with first-episode psychosis: a 2-year follow-up study
Psychiatry Res, 188 (3), 334-42
DOI 10.1016/j.psychres.2011.04.021, PubMed 21575993

Tesli M, Koefoed P, Athanasiu L, Mattingsdal M, Gustafsson O, Agartz I, Rimol LM, Brown A, Wirgenes KV, Smorr LL, Kähler AK, Werge T, Mors O, Mellerup E, Jönsson EG, Melle I, Morken G, Djurovic S, Andreassen OA (2011)
Association analysis of ANK3 gene variants in nordic bipolar disorder and schizophrenia case-control samples
Am J Med Genet B Neuropsychiatr Genet, 156B (8), 969-74
DOI 10.1002/ajmg.b.31244, PubMed 21972176

Vaskinn A, Sundet K, Simonsen C, Hellvin T, Melle I, Andreassen OA (2011)
Sex differences in neuropsychological performance and social functioning in schizophrenia and bipolar disorder
Neuropsychology, 25 (4), 499-510
DOI 10.1037/a0022677, PubMed 21463042

Aas M, Djurovic S, Athanasiu L, Steen NE, Agartz I, Lorentzen S, Sundet K, Andreassen OA, Melle I (2011)
Serotonin transporter gene polymorphism, childhood trauma, and cognition in patients with psychotic disorders
Schizophr Bull, 38 (1), 15-22
DOI 10.1093/schbul/sbr113, PubMed 21908796

Publications 2010

Aminoff SR, Jensen J, Lagerberg TV, Andreassen OA, Melle I (2010)
Decreased self-reported arousal in schizophrenia during aversive picture viewing compared to bipolar disorder and healthy controls
Psychiatry Res, 185 (3), 309-14
DOI 10.1016/j.psychres.2010.07.026, PubMed 20724003

Athanasiu L, Mattingsdal M, Kähler AK, Brown A, Gustafsson O, Agartz I, Giegling I, Muglia P, Cichon S, Rietschel M, Pietiläinen OP, Peltonen L, Bramon E, Collier D, Clair DS, Sigurdsson E, Petursson H, Rujescu D, Melle I, Steen VM, Djurovic S, Andreassen OA (2010)
Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort
J Psychiatr Res, 44 (12), 748-53
DOI 10.1016/j.jpsychires.2010.02.002, PubMed 20185149

Athanasiu L, Mattingsdal M, Melle I, Inderhaug E, Lien T, Agartz I, Lorentzen S, Morken G, Andreassen OA, Djurovic S (2010)
Intron 12 in NTRK3 is associated with bipolar disorder
Psychiatry Res, 185 (3), 358-62
DOI 10.1016/j.psychres.2010.05.011, PubMed 20554328

Barrett EA, Sundet K, Faerden A, Agartz I, Bratlien U, Romm KL, Mork E, Rossberg JI, Steen NE, Andreassen OA, Melle I (2010)
Suicidality in first episode psychosis is associated with insight and negative beliefs about psychosis
Schizophr Res, 123 (2-3), 257-62
DOI 10.1016/j.schres.2010.07.018, PubMed 20685083

Barrett EA, Sundet K, Faerden A, Nesvåg R, Agartz I, Fosse R, Mork E, Steen NE, Andreassen OA, Melle I (2010)
Suicidality before and in the early phases of first episode psychosis
Schizophr Res, 119 (1-3), 11-7
DOI 10.1016/j.schres.2010.03.022, PubMed 20399077

Barrett EA, Sundet K, Simonsen C, Agartz I, Lorentzen S, Mehlum L, Mork E, Andreassen OA, Melle I (2010)
Neurocognitive functioning and suicidality in schizophrenia spectrum disorders
Compr Psychiatry, 52 (2), 156-63
DOI 10.1016/j.comppsych.2010.06.001, PubMed 21295222

Berg AO, Melle I, Torjesen PA, Lien L, Hauff E, Andreassen OA (2010)
A cross-sectional study of vitamin D deficiency among immigrants and Norwegians with psychosis compared to the general population
J Clin Psychiatry, 71 (12), 1598-604
DOI 10.4088/JCP.09m05299yel, PubMed 20441728

Djurovic S, Gustafsson O, Mattingsdal M, Athanasiu L, Bjella T, Tesli M, Agartz I, Lorentzen S, Melle I, Morken G, Andreassen OA (2010)
A genome-wide association study of bipolar disorder in Norwegian individuals, followed by replication in Icelandic sample
J Affect Disord, 126 (1-2), 312-6
DOI 10.1016/j.jad.2010.04.007, PubMed 20451256

Faerden A, Finset A, Friis S, Agartz I, Barrett EA, Nesvåg R, Andreassen OA, Marder SR, Melle I (2010)
Apathy in first episode psychosis patients: one year follow up
Schizophr Res, 116 (1), 20-6
DOI 10.1016/j.schres.2009.10.014, PubMed 19948392

Hellvin T, Sundet K, Vaskinn A, Simonsen C, Ueland T, Andreassen OA, Melle I (2010)
Validation of the Norwegian version of the Social Functioning Scale (SFS) for schizophrenia and bipolar disorder
Scand J Psychol, 51 (6), 525-33
DOI 10.1111/j.1467-9450.2010.00839.x, PubMed 20642739

Holtze M, Saetre P, Erhardt S, Schwieler L, Werge T, Hansen T, Nielsen J, Djurovic S, Melle I, Andreassen OA, Hall H, Terenius L, Agartz I, Engberg G, Jönsson EG, Schalling M (2010)
Kynurenine 3-monooxygenase (KMO) polymorphisms in schizophrenia: an association study
Schizophr Res, 127 (1-3), 270-2
DOI 10.1016/j.schres.2010.10.002, PubMed 21030213

Hope S, Melle I, Aukrust P, Agartz I, Lorentzen S, Steen NE, Djurovic S, Ueland T, Andreassen OA (2010)
Osteoprotegerin levels in patients with severe mental disorders
J Psychiatry Neurosci, 35 (5), 304-10
DOI 10.1503/jpn.090088, PubMed 20569643

Haatveit BC, Sundet K, Hugdahl K, Ueland T, Melle I, Andreassen OA (2010)
The validity of d prime as a working memory index: results from the "Bergen n-back task"
J Clin Exp Neuropsychol, 32 (8), 871-80
DOI 10.1080/13803391003596421, PubMed 20383801

Ingason A, Giegling I, Cichon S, Hansen T, Rasmussen HB, Nielsen J, Jürgens G, Muglia P, Hartmann AM, Strengman E, Vasilescu C, Mühleisen TW, Djurovic S, Melle I, Lerer B, Möller HJ, Francks C, Pietiläinen OP, Lonnqvist J, Suvisaari J, Tuulio-Henriksson A, Walshe M, Vassos E, Di Forti M, Murray R et al. (2010)
A large replication study and meta-analysis in European samples provides further support for association of AHI1 markers with schizophrenia
Hum Mol Genet, 19 (7), 1379-86
DOI 10.1093/hmg/ddq009, PubMed 20071346

Johannessen JO, Joa I, Auestad B, Haahr U, Larsen TK, Melle I, Opjordsmoen S, Simonsen P, Rund BR, Simonsen E, Vaglum P, Friis S, McGlashan T (2010)
First-episode psychosis patients recruited into treatment via early detection teams versus ordinary pathways: course and health service use during 5 years
Early Interv Psychiatry, 5 (1), 70-5
DOI 10.1111/j.1751-7893.2010.00201.x, PubMed 21272278

Kähler AK, Djurovic S, Rimol LM, Brown AA, Athanasiu L, Jönsson EG, Hansen T, Gústafsson O, Hall H, Giegling I, Muglia P, Cichon S, Rietschel M, Pietiläinen OP, Peltonen L, Bramon E, Collier D, St Clair D, Sigurdsson E, Petursson H, Rujescu D, Melle I, Werge T, Steen VM, Dale AM et al. (2010)
Candidate gene analysis of the human natural killer-1 carbohydrate pathway and perineuronal nets in schizophrenia: B3GAT2 is associated with disease risk and cortical surface area
Biol Psychiatry, 69 (1), 90-6
DOI 10.1016/j.biopsych.2010.07.035, PubMed 20950796

Kähler AK, Otnaess MK, Wirgenes KV, Hansen T, Jönsson EG, Agartz I, Hall H, Werge T, Morken G, Mors O, Mellerup E, Dam H, Koefod P, Melle I, Steen VM, Andreassen OA, Djurovic S (2010)
Association study of PDE4B gene variants in Scandinavian schizophrenia and bipolar disorder multicenter case-control samples
Am J Med Genet B Neuropsychiatr Genet, 153B (1), 86-96
DOI 10.1002/ajmg.b.30958, PubMed 19350560

Lagerberg TV, Andreassen OA, Ringen PA, Berg AO, Larsson S, Agartz I, Sundet K, Melle I (2010)
Excessive substance use in bipolar disorder is associated with impaired functioning rather than clinical characteristics, a descriptive study
BMC Psychiatry, 10, 9
DOI 10.1186/1471-244X-10-9, PubMed 20105311

Lagerberg TV, Larsson S, Sundet K, Hansen CB, Hellvin T, Andreassen OA, Melle I (2010)
Treatment delay and excessive substance use in bipolar disorder
J Nerv Ment Dis, 198 (9), 628-33
DOI 10.1097/NMD.0b013e3181ef3ef4, PubMed 20823723

Larsen TK, Melle I, Auestad B, Haahr U, Joa I, Johannessen JO, Opjordsmoen S, Rund BR, Rossberg JI, Simonsen E, Vaglum P, Friis S, McGlashan T (2010)
Early detection of psychosis: positive effects on 5-year outcome
Psychol Med, 41 (7), 1461-9
DOI 10.1017/S0033291710002023, PubMed 20942996

Melle I, Johannessen JO, Friis S, Haahr U, Joa I, Larsen TK, Opjordsmoen S, Rund BR, Simonsen E, Vaglum P, McGlashan T (2010)
Course and predictors of suicidality over the first two years of treatment in first-episode schizophrenia spectrum psychosis
Arch Suicide Res, 14 (2), 158-70
DOI 10.1080/13811111003704787, PubMed 20455151

Melle I, Røssberg JI, Joa I, Friis S, Haahr U, Johannessen JO, Larsen TK, Opjordsmoen S, Rund BR, Simonsen E, Vaglum P, McGlashan T (2010)
The development of subjective quality of life over the first 2 years in first-episode psychosis
J Nerv Ment Dis, 198 (12), 864-9
DOI 10.1097/NMD.0b013e3181fe7258, PubMed 21135636

Nesvåg R, Lange EH, Faerden A, Barrett EA, Emilsson B, Ringen PA, Andreassen OA, Melle I, Agartz I (2010)
The use of screening instruments for detecting alcohol and other drug use disorders in first-episode psychosis
Psychiatry Res, 177 (1-2), 228-34
DOI 10.1016/j.psychres.2010.01.007, PubMed 20178887

Opjordsmoen S, Friis S, Melle I, Haahr U, Johannessen JO, Larsen TK, Røssberg JI, Rund BR, Simonsen E, Vaglum P, McGlashan TH (2010)
A 2-year follow-up of involuntary admission's influence upon adherence and outcome in first-episode psychosis
Acta Psychiatr Scand, 121 (5), 371-6
DOI 10.1111/j.1600-0447.2009.01536.x, PubMed 20085554

Rimol LM, Hartberg CB, Nesvåg R, Fennema-Notestine C, Hagler DJ, Pung CJ, Jennings RG, Haukvik UK, Lange E, Nakstad PH, Melle I, Andreassen OA, Dale AM, Agartz I (2010)
Cortical thickness and subcortical volumes in schizophrenia and bipolar disorder
Biol Psychiatry, 68 (1), 41-50
DOI 10.1016/j.biopsych.2010.03.036, PubMed 20609836

Romm KL, Rossberg JI, Berg AO, Barrett EA, Faerden A, Agartz I, Andreassen OA, Melle I (2010)
Depression and depressive symptoms in first episode psychosis
J Nerv Ment Dis, 198 (1), 67-71
DOI 10.1097/NMD.0b013e3181c81fc0, PubMed 20061872

Romm KL, Rossberg JI, Berg AO, Hansen CF, Andreassen OA, Melle I (2010)
Assessment of social anxiety in first episode psychosis using the Liebowitz Social Anxiety scale as a self-report measure
Eur Psychiatry, 26 (2), 115-21
DOI 10.1016/j.eurpsy.2010.08.014, PubMed 21036553

Rossberg JI, Johannessen JO, Klungsoyr O, Opjordsmoen S, Evensen J, Fjell A, Haahr U, Joa I, Langeveld J, Larsen TK, Melle I, Rund BR, Simonsen E, ten Velden W, Vaglum P, Friis S, McGlashan T (2010)
Are multi family groups appropriate for patients with first episode psychosis? A 5-year naturalistic follow-up study
Acta Psychiatr Scand, 122 (5), 384-94
DOI 10.1111/j.1600-0447.2010.01571.x, PubMed 20491714

Saetre P, Lundmark P, Wang A, Hansen T, Rasmussen HB, Djurovic S, Melle I, Andreassen OA, Werge T, Agartz I, Hall H, Terenius L, Jönsson EG (2010)
The tryptophan hydroxylase 1 (TPH1) gene, schizophrenia susceptibility, and suicidal behavior: a multi-centre case-control study and meta-analysis
Am J Med Genet B Neuropsychiatr Genet, 153B (2), 387-396
DOI 10.1002/ajmg.b.30991, PubMed 19526457

Sagen U, Faerden A, Haug T, Melle I, Finset A, Dammen T (2010)
Are there common core features of apathy in different neuropsychiatric samples as assessed by the Apathy Evaluation Scale?
Nord J Psychiatry, 64 (1), 49-57
DOI 10.3109/08039480903274415, PubMed 19883192

Simonsen C, Sundet K, Vaskinn A, Ueland T, Romm KL, Hellvin T, Melle I, Friis S, Andreassen OA (2010)
Psychosocial function in schizophrenia and bipolar disorder: Relationship to neurocognition and clinical symptoms
J Int Neuropsychol Soc, 16 (5), 771-83
DOI 10.1017/S1355617710000573, PubMed 20509984

Simonsen E, Friis S, Opjordsmoen S, Mortensen EL, Haahr U, Melle I, Joa I, Johannessen JO, Larsen TK, Røssberg JI, Rund BR, Vaglum P, McGlashan TH (2010)
Early identification of non-remission in first-episode psychosis in a two-year outcome study
Acta Psychiatr Scand, 122 (5), 375-83
DOI 10.1111/j.1600-0447.2010.01598.x, PubMed 20722632

Steen NE, Tesli M, Kähler AK, Methlie P, Hope S, Barrett EA, Larsson S, Mork E, Løvås K, Røssberg JI, Agartz I, Melle I, Djurovic S, Lorentzen S, Berg JP, Andreassen OA (2010)
SRD5A2 is associated with increased cortisol metabolism in schizophrenia spectrum disorders
Prog Neuropsychopharmacol Biol Psychiatry, 34 (8), 1500-6
DOI 10.1016/j.pnpbp.2010.08.013, PubMed 20800085

Steinberg S, Mors O, Børglum AD, Gustafsson O, Werge T, Mortensen PB, Andreassen OA, Sigurdsson E, Thorgeirsson TE, Böttcher Y, Olason P, Ophoff RA, Cichon S, Gudjonsdottir IH, Pietiläinen OP, Nyegaard M, Tuulio-Henriksson A, Ingason A, Hansen T, Athanasiu L, Suvisaari J, Lonnqvist J, Paunio T, Hartmann A, Jürgens G et al. (2010)
Expanding the range of ZNF804A variants conferring risk of psychosis
Mol Psychiatry, 16 (1), 59-66
DOI 10.1038/mp.2009.149, PubMed 20048749

Tesli M, Athanasiu L, Mattingsdal M, Kähler AK, Gustafsson O, Andreassen BK, Werge T, Hansen T, Mors O, Mellerup E, Koefoed P, Jönsson EG, Agartz I, Melle I, Morken G, Djurovic S, Andreassen OA (2010)
Association analysis of PALB2 and BRCA2 in bipolar disorder and schizophrenia in a scandinavian case-control sample
Am J Med Genet B Neuropsychiatr Genet, 153B (7), 1276-82
DOI 10.1002/ajmg.b.31098, PubMed 20872766

Vares M, Saetre P, Deng H, Cai G, Liu X, Hansen T, Rasmussen HB, Werge T, Melle I, Djurovic S, Andreassen OA, Agartz I, Hall H, Terenius L, Jönsson EG (2010)
Association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age of onset in schizophrenia
Am J Med Genet B Neuropsychiatr Genet, 153B (2), 610-618
DOI 10.1002/ajmg.b.31030, PubMed 19746410

Wirgenes KV, Djurovic S, Sundet K, Agartz I, Mattingsdal M, Athanasiu L, Melle I, Andreassen OA (2010)
Catechol O-methyltransferase variants and cognitive performance in schizophrenia and bipolar disorder versus controls
Schizophr Res, 122 (1-3), 31-7
DOI 10.1016/j.schres.2010.05.007, PubMed 20605701

Publications 2009

Andreou D, Saetre P, Lundmark P, Hansen T, Timm S, Melle I, Djurovic S, Andreassen OA, Werge T, Hall H, Agartz I, Terenius L, Jönsson EG (2009)
Tyrosine hydroxylase Val81Met polymorphism: lack of association with schizophrenia
Psychiatr Genet, 19 (5), 273-4
DOI 10.1097/YPG.0b013e32832a4fcd, PubMed 19491717

Djurovic S, Le Hellard S, Kähler AK, Jönsson EG, Agartz I, Steen VM, Hall H, Wang AG, Rasmussen HB, Melle I, Werge T, Andreassen OA (2009)
Association of MCTP2 gene variants with schizophrenia in three independent samples of Scandinavian origin (SCOPE)
Psychiatry Res, 168 (3), 256-8
DOI 10.1016/j.psychres.2008.08.007, PubMed 19223264

Faerden A, Friis S, Agartz I, Barrett EA, Nesvåg R, Finset A, Melle I (2009)
Apathy and functioning in first-episode psychosis
Psychiatr Serv, 60 (11), 1495-503
DOI 10.1176/ps.2009.60.11.1495, PubMed 19880468

Faerden A, Vaskinn A, Finset A, Agartz I, Ann Barrett E, Friis S, Simonsen C, Andreassen OA, Melle I (2009)
Apathy is associated with executive functioning in first episode psychosis
BMC Psychiatry, 9, 1
DOI 10.1186/1471-244X-9-1, PubMed 19133132

Hansen CF, Torgalsbøen AK, Melle I, Bell MD (2009)
Passive/apathetic social withdrawal and active social avoidance in schizophrenia: difference in underlying psychological processes
J Nerv Ment Dis, 197 (4), 274-7
DOI 10.1097/NMD.0b013e31819dbd36, PubMed 19363384

Holmén A, Juuhl-Langseth M, Thormodsen R, Melle I, Rund BR (2009)
Neuropsychological profile in early-onset schizophrenia-spectrum disorders: measured with the MATRICS battery
Schizophr Bull, 36 (4), 852-9
DOI 10.1093/schbul/sbn174, PubMed 19223656

Hope S, Melle I, Aukrust P, Steen NE, Birkenaes AB, Lorentzen S, Agartz I, Ueland T, Andreassen OA (2009)
Similar immune profile in bipolar disorder and schizophrenia: selective increase in soluble tumor necrosis factor receptor I and von Willebrand factor
Bipolar Disord, 11 (7), 726-34
DOI 10.1111/j.1399-5618.2009.00757.x, PubMed 19839997

Joa I, Johannessen JO, Langeveld J, Friis S, Melle I, Opjordsmoen S, Simonsen E, Vaglum P, McGlashan T, Larsen TK (2009)
Baseline profiles of adolescent vs. adult-onset first-episode psychosis in an early detection program
Acta Psychiatr Scand, 119 (6), 494-500
DOI 10.1111/j.1600-0447.2008.01338.x, PubMed 19207132

Joyner AH, J CR, Bloss CS, Bakken TE, Rimol LM, Melle I, Agartz I, Djurovic S, Topol EJ, Schork NJ, Andreassen OA, Dale AM (2009)
A common MECP2 haplotype associates with reduced cortical surface area in humans in two independent populations
Proc Natl Acad Sci U S A, 106 (36), 15483-8
DOI 10.1073/pnas.0901866106, PubMed 19717458

Jönsson EG, Saetre P, Vares M, Andreou D, Larsson K, Timm S, Rasmussen HB, Djurovic S, Melle I, Andreassen OA, Agartz I, Werge T, Hall H, Terenius L (2009)
DTNBP1, NRG1, DAOA, DAO and GRM3 polymorphisms and schizophrenia: an association study
Neuropsychobiology, 59 (3), 142-50
DOI 10.1159/000218076, PubMed 19439994

Larsson S, Lorentzen S, Mork E, Barrett EA, Steen NE, Lagerberg TV, Berg AO, Aminoff SR, Agartz I, Melle I, Andreassen OA (2009)
Age at onset of bipolar disorder in a Norwegian catchment area sample
J Affect Disord, 124 (1-2), 174-7
DOI 10.1016/j.jad.2009.10.031, PubMed 19931918

Opjordsmoen S, Melle I, Friis S, Haahr U, Johannessen JO, Larsen TK, Rund BR, Simonsen E, Vaglum P, McGlashan TH (2009)
Stability of medication in early psychosis: a comparison between second-generation and low-dose first-generation antipsychotics
Early Interv Psychiatry, 3 (1), 58-65
DOI 10.1111/j.1751-7893.2008.00103.x, PubMed 21352176

Otnaess MK, Djurovic S, Rimol LM, Kulle B, Kähler AK, Jönsson EG, Agartz I, Sundet K, Hall H, Timm S, Hansen T, Callicott JH, Melle I, Werge T, Andreassen OA (2009)
Evidence for a possible association of neurotrophin receptor (NTRK-3) gene polymorphisms with hippocampal function and schizophrenia
Neurobiol Dis, 34 (3), 518-24
DOI 10.1016/j.nbd.2009.03.011, PubMed 19344762

Rimol LM, Agartz I, Djurovic S, Brown AA, Roddey JC, Kähler AK, Mattingsdal M, Athanasiu L, Joyner AH, Schork NJ, Halgren E, Sundet K, Melle I, Dale AM, Andreassen OA, Alzheimer's Disease Neuroimaging Initiative (2009)
Sex-dependent association of common variants of microcephaly genes with brain structure
Proc Natl Acad Sci U S A, 107 (1), 384-8
DOI 10.1073/pnas.0908454107, PubMed 20080800

Ringen PA, Vaskinn A, Sundet K, Engh JA, Jónsdóttir H, Simonsen C, Friis S, Opjordsmoen S, Melle I, Andreassen OA (2009)
Opposite relationships between cannabis use and neurocognitive functioning in bipolar disorder and schizophrenia
Psychol Med, 40 (8), 1337-47
DOI 10.1017/S0033291709991620, PubMed 19891810

Simonsen C, Sundet K, Vaskinn A, Birkenaes AB, Engh JA, Faerden A, Jónsdóttir H, Ringen PA, Opjordsmoen S, Melle I, Friis S, Andreassen OA (2009)
Neurocognitive dysfunction in bipolar and schizophrenia spectrum disorders depends on history of psychosis rather than diagnostic group
Schizophr Bull, 37 (1), 73-83
DOI 10.1093/schbul/sbp034, PubMed 19443616

Stefansson H, Ophoff RA, Steinberg S, Andreassen OA, Cichon S, Rujescu D, Werge T, Pietiläinen OP, Mors O, Mortensen PB, Sigurdsson E, Gustafsson O, Nyegaard M, Tuulio-Henriksson A, Ingason A, Hansen T, Suvisaari J, Lonnqvist J, Paunio T, Børglum AD, Hartmann A, Fink-Jensen A, Nordentoft M, Hougaard D, Norgaard-Pedersen B et al. (2009)
Common variants conferring risk of schizophrenia
Nature, 460 (7256), 744-7
DOI 10.1038/nature08186, PubMed 19571808

Tesli M, Kähler AK, Andreassen BK, Werge T, Mors O, Mellerup E, Koefoed P, Melle I, Morken G, Wirgenes KV, Andreassen OA, Djurovic S (2009)
No association between DGKH and bipolar disorder in a Scandinavian case-control sample
Psychiatr Genet, 19 (5), 269-72
DOI 10.1097/YPG.0b013e32832d302f, PubMed 19478689

Welander-Vatn AS, Jensen J, Lycke C, Agartz I, Server A, Gadmar ØB, Melle I, Nakstad PH, Andreassen OA (2009)
No altered dorsal anterior cingulate activation in bipolar II disorder patients during a Go/No-go task: an fMRI study
Bipolar Disord, 11 (3), 270-9
DOI 10.1111/j.1399-5618.2009.00680.x, PubMed 19419384

Wirgenes KV, Djurovic S, Agartz I, Jonsson EG, Werge T, Melle I, Andreassen OA (2009)
Dysbindin and d-amino-acid-oxidase gene polymorphisms associated with positive and negative symptoms in schizophrenia
Neuropsychobiology, 60 (1), 31-6
DOI 10.1159/000235799, PubMed 19729970

Publications 2008

Djurovic S, Kähler AK, Kulle B, Jönsson EG, Agartz I, Le Hellard S, Hall H, Jakobsen KD, Hansen T, Melle I, Werge T, Steen VM, Andreassen OA (2008)
A possible association between schizophrenia and GRIK3 polymorphisms in a multicenter sample of Scandinavian origin (SCOPE)
Schizophr Res, 107 (2-3), 242-8
DOI 10.1016/j.schres.2008.10.010, PubMed 19022628

Haahr U, Friis S, Larsen TK, Melle I, Johannessen JO, Opjordsmoen S, Simonsen E, Rund BR, Vaglum P, McGlashan T (2008)
First-episode psychosis: diagnostic stability over one and two years
Psychopathology, 41 (5), 322-9
DOI 10.1159/000146070, PubMed 18635935

Kähler AK, Djurovic S, Kulle B, Jönsson EG, Agartz I, Hall H, Opjordsmoen S, Jakobsen KD, Hansen T, Melle I, Werge T, Steen VM, Andreassen OA (2008)
Association analysis of schizophrenia on 18 genes involved in neuronal migration: MDGA1 as a new susceptibility gene
Am J Med Genet B Neuropsychiatr Genet, 147B (7), 1089-100
DOI 10.1002/ajmg.b.30726, PubMed 18384059

Le Hellard S, Mühleisen TW, Djurovic S, Fernø J, Ouriaghi Z, Mattheisen M, Vasilescu C, Raeder MB, Hansen T, Strohmaier J, Georgi A, Brockschmidt FF, Melle I, Nenadic I, Sauer H, Rietschel M, Nöthen MM, Werge T, Andreassen OA, Cichon S, Steen VM (2008)
Polymorphisms in SREBF1 and SREBF2, two antipsychotic-activated transcription factors controlling cellular lipogenesis, are associated with schizophrenia in German and Scandinavian samples
Mol Psychiatry, 15 (5), 463-72
DOI 10.1038/mp.2008.110, PubMed 18936756

Melle I, Larsen TK, Haahr U, Friis S, Johannesen JO, Opjordsmoen S, Rund BR, Simonsen E, Vaglum P, McGlashan T (2008)
Prevention of negative symptom psychopathologies in first-episode schizophrenia: two-year effects of reducing the duration of untreated psychosis
Arch Gen Psychiatry, 65 (6), 634-40
DOI 10.1001/archpsyc.65.6.634, PubMed 18519821

Olsen L, Hansen T, Jakobsen KD, Djurovic S, Melle I, Agartz I, Hall H, Ullum H, Timm S, Wang AG, Jönsson EG, Andreassen OA, Werge T (2008)
The estrogen hypothesis of schizophrenia implicates glucose metabolism: association study in three independent samples
BMC Med Genet, 9, 39
DOI 10.1186/1471-2350-9-39, PubMed 18460190

Ringen PA, Melle I, Birkenaes AB, Engh JA, Faerden A, Vaskinn A, Friis S, Opjordsmoen S, Andreassen OA (2008)
The level of illicit drug use is related to symptoms and premorbid functioning in severe mental illness
Acta Psychiatr Scand, 118 (4), 297-304
DOI 10.1111/j.1600-0447.2008.01244.x, PubMed 18759810

Rossberg JI, Melle I, Opjordsmoen S, Friis S (2008)
The relationship between staff members' working conditions and patients' perceptions of the treatment environment
Int J Soc Psychiatry, 54 (5), 437-46
DOI 10.1177/0020764008090689, PubMed 18786905

Rujescu D, Ingason A, Cichon S, Pietiläinen OP, Barnes MR, Toulopoulou T, Picchioni M, Vassos E, Ettinger U, Bramon E, Murray R, Ruggeri M, Tosato S, Bonetto C, Steinberg S, Sigurdsson E, Sigmundsson T, Petursson H, Gylfason A, Olason PI, Hardarsson G, Jonsdottir GA, Gustafsson O, Fossdal R, Giegling I et al. (2008)
Disruption of the neurexin 1 gene is associated with schizophrenia
Hum Mol Genet, 18 (5), 988-96
DOI 10.1093/hmg/ddn351, PubMed 18945720

Simonsen E, Haahr U, Mortensen EL, Friis S, Johannessen JO, Larsen TK, Melle I, Opjordsmoen S, Rund BR, McGlashan T, Vaglum P (2008)
Personality disorders in first-episode psychosis
Personal. Ment. Health, 2 (4), 230-239
DOI 10.1002/pmh.49

Stefansson H, Rujescu D, Cichon S, Pietiläinen OP, Ingason A, Steinberg S, Fossdal R, Sigurdsson E, Sigmundsson T, Buizer-Voskamp JE, Hansen T, Jakobsen KD, Muglia P, Francks C, Matthews PM, Gylfason A, Halldorsson BV, Gudbjartsson D, Thorgeirsson TE, Sigurdsson A, Jonasdottir A, Jonasdottir A, Bjornsson A, Mattiasdottir S, Blondal T et al. (2008)
Large recurrent microdeletions associated with schizophrenia
Nature, 455 (7210), 232-6
DOI 10.1038/nature07229, PubMed 18668039

Publications 2007

Faerden A, Nesvåg R, Barrett EA, Agartz I, Finset A, Friis S, Rossberg JI, Melle I (2007)
Assessing apathy: the use of the Apathy Evaluation Scale in first episode psychosis
Eur Psychiatry, 23 (1), 33-9
DOI 10.1016/j.eurpsy.2007.09.002, PubMed 18029152

Fjell A, Bloch Thorsen GR, Friis S, Johannessen JO, Larsen TK, Lie K, Lyse HG, Melle I, Simonsen E, Smeby NA, Øxnevad AL, McFarlane WR, Vaglum P, McGlashan T (2007)
Multifamily group treatment in a program for patients with first-episode psychosis: experiences from the TIPS project
Psychiatr Serv, 58 (2), 171-3
DOI 10.1176/ps.2007.58.2.171, PubMed 17287370

Friis S, Andreassen OA, Melle I (2007)
Psykiatriske forskningsmetoder
In Epidemiologiske og kliniske forskningsmetoder, Gyldendal akademisk, Oslo, [373]-[400]
BIBSYS 071650067

Hansen T, Olsen L, Lindow M, Jakobsen KD, Ullum H, Jonsson E, Andreassen OA, Djurovic S, Melle I, Agartz I, Hall H, Timm S, Wang AG, Werge T (2007)
Brain expressed microRNAs implicated in schizophrenia etiology
PLoS One, 2 (9), e873
DOI 10.1371/journal.pone.0000873, PubMed 17849003

Joa I, Johannessen JO, Auestad B, Friis S, McGlashan T, Melle I, Opjordsmoen S, Simonsen E, Vaglum P, Larsen TK (2007)
The key to reducing duration of untreated first psychosis: information campaigns
Schizophr Bull, 34 (3), 466-72
DOI 10.1093/schbul/sbm095, PubMed 17905788

Johannessen JO, Friis S, Joa I, Haahr U, Larsen TK, Melle I, Opjordsmoen S, Rund BR, Simonsen E, Vaglum P, McGlashan T (2007)
First-episode psychosis patients recruited into treatment via early detection teams versus ordinary pathways: course, outcome and health service use during first 2 years
Early Interv Psychiatry, 1 (1), 40-8
DOI 10.1111/j.1751-7893.2007.00003.x, PubMed 21352107

Larsen TK, Melle I, Friis S, Joa I, Johannessen JO, Opjordsmoen S, Simonsen E, Vaglum P, McGlashan TH (2007)
One-year effect of changing duration of untreated psychosis in a single catchment area
Br J Psychiatry Suppl, 51, s128-32
DOI 10.1192/bjp.191.51.s128, PubMed 18055929

Ringen PA, Lagerberg TV, Birkenaes AB, Engn J, Faerden A, Jónsdottir H, Nesvåg R, Friis S, Opjordsmoen S, Larsen F, Melle I, Andreassen OA (2007)
Differences in prevalence and patterns of substance use in schizophrenia and bipolar disorder
Psychol Med, 38 (9), 1241-9
DOI 10.1017/S003329170700236X, PubMed 18070373

Ringen PA, Melle I, Birkenaes AB, Engh JA, Faerden A, Jónsdóttir H, Nesvåg R, Vaskinn A, Friis S, Larsen F, Opjordsmoen S, Sundet K, Andreassen OA (2007)
Illicit drug use in patients with psychotic disorders compared with that in the general population: a cross-sectional study
Acta Psychiatr Scand, 117 (2), 133-8
DOI 10.1111/j.1600-0447.2007.01135.x, PubMed 18081921

Rund BR, Melle I, Friis S, Johannessen JO, Larsen TK, Midbøe LJ, Opjordsmoen S, Simonsen E, Vaglum P, McGlashan T (2007)
The course of neurocognitive functioning in first-episode psychosis and its relation to premorbid adjustment, duration of untreated psychosis, and relapse
Schizophr Res, 91 (1-3), 132-40
DOI 10.1016/j.schres.2006.11.030, PubMed 17258891

Simonsen E, Friis S, Haahr U, Johannessen JO, Larsen TK, Melle I, Opjordsmoen S, Rund BR, Vaglum P, McGlashan T (2007)
Clinical epidemiologic first-episode psychosis: 1-year outcome and predictors
Acta Psychiatr Scand, 116 (1), 54-61
DOI 10.1111/j.1600-0447.2006.00942.x, PubMed 17559601

Publications 2006

Larsen TK, Melle I, Auestad B, Friis S, Haahr U, Johannessen JO, Opjordsmoen S, Rund BR, Simonsen E, Vaglum P, McGlashan T (2006)
Early detection of first-episode psychosis: the effect on 1-year outcome
Schizophr Bull, 32 (4), 758-64
DOI 10.1093/schbul/sbl005, PubMed 16809640

Larsen TK, Melle I, Auestad B, Friis S, Haahr U, Johannessen JO, Opjordsmoen S, Rund BR, Simonsen E, Vaglum P, McGlashan TH (2006)
Substance abuse in first-episode non-affective psychosis
Schizophr Res, 88 (1-3), 55-62
DOI 10.1016/j.schres.2006.07.018, PubMed 16971092

Melle I, Johannesen JO, Friis S, Haahr U, Joa I, Larsen TK, Opjordsmoen S, Rund BR, Simonsen E, Vaglum P, McGlashan T (2006)
Early detection of the first episode of schizophrenia and suicidal behavior
Am J Psychiatry, 163 (5), 800-4
DOI 10.1176/ajp.2006.163.5.800, PubMed 16648319

Melle I, Skymoen LR, Thomassen C, Helli LN (2006)
Kliniske psykiatri-skalaer
Eli Lilly Norge AS, Oslo, 76 s.
BIBSYS 061051241

Røssberg JI, Melle I, Opjordsmoen S, Friis S (2006)
Patient satisfaction and treatment environment: a 20-year follow-up study from an acute psychiatric ward
Nord J Psychiatry, 60 (2), 176-80
DOI 10.1080/08039480600583894, PubMed 16635939

Publications 2005

Friis S, Vaglum P, Haahr U, Johannessen JO, Larsen TK, Melle I, Opjordsmoen S, Rund BR, Simonsen E, McGlashan TH (2005)
Effect of an early detection programme on duration of untreated psychosis: part of the Scandinavian TIPS study
Br J Psychiatry Suppl, 48, s29-32
DOI 10.1192/bjp.187.48.s29, PubMed 16055804

Johannessen JO, Larsen TK, Joa I, Melle I, Friis S, Opjordsmoen S, Rund BR, Simonsen E, Vaglum P, McGlashan TH (2005)
Pathways to care for first-episode psychosis in an early detection healthcare sector: part of the Scandinavian TIPS study
Br J Psychiatry Suppl, 48, s24-8
DOI 10.1192/bjp.187.48.s24, PubMed 16055803

Kjær R, Linderoth L, Melle I (2005)
Fram: rehabilitering ved schizofreni
[AstraZeneca], Oslo, 243 s.
BIBSYS 06056458x, ISBN 82-90683-11-1

Melle I, Friis S, Haahr U, Johannesen JO, Larsen TK, Opjordsmoen S, Roessberg JI, Rund BR, Simonsen E, Vaglum P, McGlashan T (2005)
Measuring quality of life in first-episode psychosis
Eur Psychiatry, 20 (7), 474-83
DOI 10.1016/j.eurpsy.2005.03.002, PubMed 15967642

Melle I, Haahr U, Friis S, Hustoft K, Johannessen JO, Larsen TK, Opjordsmoen S, Rund BR, Simonsen E, Vaglum P, McGlashan T (2005)
Reducing the duration of untreated first-episode psychosis -- effects on baseline social functioning and quality of life
Acta Psychiatr Scand, 112 (6), 469-73
DOI 10.1111/j.1600-0447.2005.00638.x, PubMed 16279877

Publications 2004

Friis S, Melle I, Larsen TK, Haahr U, Johannessen JO, Simonsen E, Opjordsmoen S, Vaglum P, McGlashan TH (2004)
Does duration of untreated psychosis bias study samples of first-episode psychosis?
Acta Psychiatr Scand, 110 (4), 286-91
DOI 10.1111/j.1600-0447.2004.00381.x, PubMed 15352930

Larsen TK, Friis S, Haahr U, Johannessen JO, Melle I, Opjordsmoen S, Rund BR, Simonsen E, Vaglum PV, McGlashan TH (2004)
Premorbid adjustment in first-episode non-affective psychosis: distinct patterns of pre-onset course
Br J Psychiatry, 185, 108-15
DOI 10.1192/bjp.185.2.108, PubMed 15286061

Melle I, Larsen TK, Haahr U, Friis S, Johannessen JO, Opjordsmoen S, Simonsen E, Rund BR, Vaglum P, McGlashan T (2004)
Reducing the duration of untreated first-episode psychosis: effects on clinical presentation
Arch Gen Psychiatry, 61 (2), 143-50
DOI 10.1001/archpsyc.61.2.143, PubMed 14757590

Rund BR, Melle I, Friis S, Larsen TK, Midbøe LJ, Opjordsmoen S, Simonsen E, Vaglum P, McGlashan T (2004)
Neurocognitive dysfunction in first-episode psychosis: correlates with symptoms, premorbid adjustment, and duration of untreated psychosis
Am J Psychiatry, 161 (3), 466-72
DOI 10.1176/appi.ajp.161.3.466, PubMed 14992972

Publications 2003

Friis S, Larsen TK, Melle I (2003)
[Therapy of psychoses]
Tidsskr Nor Laegeforen, 123 (10), 1393
PubMed 12806685

Friis S, Larsen TK, Melle I, Opjordsmoen S, Johannessen JO, Haahr U, Simonsen E, Rund BR, Vaglum P, McGlashan T (2003)
Methodological pitfalls in early detection studies - the NAPE Lecture 2002. Nordic Association for Psychiatric Epidemiology
Acta Psychiatr Scand, 107 (1), 3-9
DOI 10.1034/j.1600-0447.2003.02600.x, PubMed 12558535

Publications 2002

Hauff E, Varvin S, Laake P, Melle I, Vaglum P, Friis S (2002)
Inpatient psychotherapy compared with usual care for patients who have schizophrenic psychoses
Psychiatr Serv, 53 (4), 471-3
DOI 10.1176/appi.ps.53.4.471, PubMed 11919362

Melle I, Johansen R (2002)
[The invisible children--when mother or father have schizophrenia]
Tidsskr Nor Laegeforen, 122 (23), 2299-302
PubMed 12448273

Publications 2001

Johannessen JO, McGlashan TH, Larsen TK, Horneland M, Joa I, Mardal S, Kvebaek R, Friis S, Melle I, Opjordsmoen S, Simonsen E, Ulrik H, Vaglum P (2001)
Early detection strategies for untreated first-episode psychosis
Schizophr Res, 51 (1), 39-46
DOI 10.1016/s0920-9964(01)00237-7, PubMed 11479064

Larsen TK, Friis S, Haahr U, Joa I, Johannessen JO, Melle I, Opjordsmoen S, Simonsen E, Vaglum P (2001)
Early detection and intervention in first-episode schizophrenia: a critical review
Acta Psychiatr Scand, 103 (5), 323-34
DOI 10.1034/j.1600-0447.2001.00131.x, PubMed 11380302

Larsen TK, McGlashan TH, Johannessen JO, Friis S, Guldberg C, Haahr U, Horneland M, Melle I, Moe LC, Opjordsmoen S, Simonsen E, Vaglum P (2001)
Shortened duration of untreated first episode of psychosis: changes in patient characteristics at treatment
Am J Psychiatry, 158 (11), 1917-9
DOI 10.1176/appi.ajp.158.11.1917, PubMed 11691702

Publications 2000

Melle I (2000)
Patients with schizophrenia from one catchment area: a seven-year follow-up study
Division of Psychiatry, Ullevål Hospital, University of Oslo, Oslo, 1 b. (flere pag.)
BIBSYS 000837792, ISBN 82-91049-30-0

Melle I, Friis S, Hauff E, Vaglum P (2000)
Social functioning of patients with schizophrenia in high-income welfare societies
Psychiatr Serv, 51 (2), 223-8
DOI 10.1176/appi.ps.51.2.223, PubMed 10655007

Melle I, Friis S, Hauff E, Vaglum P (2000)
Patients with schizophrenia after the acute ward: Seven years' service utilization and clinical course
Nord. J. Psychiatr., 54 (1), 47-54
DOI 10.1080/080394800427573

Publications 1996

Melle I, Friis S, Hauff E, Island TK, Lorentzen S, Vaglum P (1996)
The importance of ward atmosphere in inpatient treatment of schizophrenia on short-term units
Psychiatr Serv, 47 (7), 721-6
DOI 10.1176/ps.47.7.721, PubMed 8807685

Publications 1991

Friis S, Hauff E, Island TK, Lorentzen S, Melle I, Vaglum P (1991)
The Ullevål acute ward follow-up study: a personal 7-year follow-up of patients with functional psychosis admitted to the acute ward of a catchment area
Psychopathology, 24 (5), 316-27
DOI 10.1159/000284732, PubMed 1784708