Elisabeth Leere Øiestad
- Senior Scientist, Associate Professor; PhD
- +47 23 01 30 66
Publications 2024
Enantiomer-specific analysis of amphetamine in urine, oral fluid and blood
J Anal Toxicol, 48 (5), 254-262
DOI 10.1093/jat/bkae038, PubMed 38706158
Drugs in blood and urine samples from victims of suspected exposure to drink spiking: A prospective observational study from Oslo, Norway
PLoS One, 19 (7), e0306191
DOI 10.1371/journal.pone.0306191, PubMed 38985694
Solvent-free parallel artificial liquid membrane extraction for drugs of abuse in plasma samples using LC-MS/MS
Anal Chim Acta, 1301, 342387
DOI 10.1016/j.aca.2024.342387, PubMed 38553114
Electromembrane extraction of drugs of abuse and prescription drugs from micropulverized hair
J Anal Toxicol, 48 (7), 489-498
DOI 10.1093/jat/bkae051, PubMed 38905017
Publications 2023
Drug analysis: Comparison between dried plasma spots and liquid plasma samples of trauma patients from Cameroon-A feasibility study
Drug Test Anal, 16 (3), 303-308
DOI 10.1002/dta.3545, PubMed 37464568
High-throughput quantification of emerging "nitazene" benzimidazole opioid analogs by microextraction and UHPLC-MS-MS
J Anal Toxicol, 47 (9), 787-796
DOI 10.1093/jat/bkad071, PubMed 37700512
Conductive vial electromembrane extraction of opioids from oral fluid
Anal Bioanal Chem, 415 (22), 5323-5335
DOI 10.1007/s00216-023-04807-3, PubMed 37386201
Determination of amphetamine enantiomers in urine by conductive vial electromembrane extraction and ultra-high performance supercritical fluid chromatography tandem mass spectrometry
Drug Test Anal, 15 (8), 909-918
DOI 10.1002/dta.3487, PubMed 37114617
Comparative Study of Postmortem Concentrations of Benzodiazepines and Z-Hypnotics in Several Different Matrices
J Anal Toxicol, 47 (3), 287-298
DOI 10.1093/jat/bkac106, PubMed 36542823
Publications 2021
Green and sustainable drug analysis-Combining microsampling and microextraction of drugs of abuse
SUSTAIN. CHEM. PHARM., 24, 100517
DOI 10.1016/j.scp.2021.100517
Novel approaches and green sample preparation in bioanalytical protocols
SUSTAIN. CHEM. PHARM., 24, 100559
DOI 10.1016/j.scp.2021.100559
Distribution of tetrahydrocannabinol and cannabidiol in several different postmortem matrices
Forensic Sci Int, 329, 111082
DOI 10.1016/j.forsciint.2021.111082, PubMed 34775328
Membrane-based liquid-phase microextraction of basic pharmaceuticals - A study on the optimal extraction window
J Chromatogr A, 1664, 462769
DOI 10.1016/j.chroma.2021.462769, PubMed 34998024
Determination of psychoactive drugs in serum using conductive vial electromembrane extraction combined with UHPLC-MS/MS
J Chromatogr B Analyt Technol Biomed Life Sci, 1183, 122926
DOI 10.1016/j.jchromb.2021.122926, PubMed 34624684
Publications 2020
Electromembrane extraction of anthracyclines from plasma: Comparison with conventional extraction techniques
Talanta, 223 (Pt 2), 121748
DOI 10.1016/j.talanta.2020.121748, PubMed 33298272
Electromembrane Extraction with Vitals of Counducting Polymer
LCGCN North America, 38 (8), 435-439
PublikaID 355
Impact of ion balance in electromembrane extraction
Anal Chim Acta, 1124, 129-136
DOI 10.1016/j.aca.2020.05.039, PubMed 32534665
Bioanalysis of pharmaceuticals using liquid-phase microextraction combined with liquid chromatography-mass spectrometry
J Pharm Biomed Anal, 189, 113446
DOI 10.1016/j.jpba.2020.113446, PubMed 32619730
Electromembrane extraction of highly polar bases from biological samples - Deeper insight into bis(2-ethylhexyl) phosphate as ionic carrier
Anal Chim Acta, 1115, 23-32
DOI 10.1016/j.aca.2020.04.027, PubMed 32370866
Electromembrane extraction using deep eutectic solvents as the liquid membrane
Anal Chim Acta, 1143, 109-116
DOI 10.1016/j.aca.2020.11.044, PubMed 33384108
Comparison of anticoagulant rodenticide concentrations in liver and feces from apparently healthy red foxes
J Vet Diagn Invest, 32 (4), 560-564
DOI 10.1177/1040638720927365, PubMed 32476615
Determination of anticoagulant rodenticides in faeces of exposed dogs and in a healthy dog population
Acta Vet Scand, 62 (1), 30
DOI 10.1186/s13028-020-00531-5, PubMed 32546243
Publications 2019
Liquid-phase microextraction in 96-well plates - calibration and accurate quantification of pharmaceuticals in human plasma samples
J Chromatogr A, 1602, 117-123
DOI 10.1016/j.chroma.2019.06.013, PubMed 31229251
Identification and Assessment of Drug-User Groups Among Nightlife Attendees: Self-Reports, Breathalyzer-Tests and Oral Fluid Drug Tests
Eur Addict Res, 25 (2), 93-102
DOI 10.1159/000497318, PubMed 30783038
Detection Time of Oxazepam and Zopiclone in Urine and Oral Fluid after Experimental Oral Dosing
J Anal Toxicol, 43 (5), 369-377
DOI 10.1093/jat/bky083, PubMed 30615130
Interpreting oral fluid drug results in prisoners: monitoring current drug intake and detection times for drugs self-administered prior to detention
Forensic Toxicol., 37 (1), 59-74
DOI 10.1007/s11419-018-0434-9
PREVALENCE OF ANTICOAGULANT RODENTICIDES IN FECES OF WILD RED FOXES (VULPES VULPES) IN NORWAY
J Wildl Dis, 55 (4), 834-843
DOI 10.7589/2019-01-027, PubMed 31112468
An Experimental Study of Diazepam and Alprazolam Kinetics in Urine and Oral Fluid Following Single Oral Doses
J Anal Toxicol, 43 (2), 104-111
DOI 10.1093/jat/bky062, PubMed 30517712
Electromembrane extraction with solvent modification of the acceptor solution: improved mass transfer of drugs of abuse from human plasma
Bioanalysis, 11 (8), 755-771
DOI 10.4155/bio-2018-0308, PubMed 30994001
Publications 2018
Dried blood spots and parallel artificial liquid membrane extraction-A simple combination of microsampling and microextraction
Anal Chim Acta, 1009, 56-64
DOI 10.1016/j.aca.2018.01.024, PubMed 29422132
A Monoclonal Antibody against 6-Acetylmorphine Protects Female Mice Offspring from Adverse Behavioral Effects Induced by Prenatal Heroin Exposure
J Pharmacol Exp Ther, 368 (1), 106-115
DOI 10.1124/jpet.118.251504, PubMed 30361238
Separation of isomers of new psychoactive substances and isotope-labeled amphetamines using UHPSFC-MS/MS and UHPLC-MS/MS
J. Liq. Chromatogr. Relat. Technol., 41 (7), 391-400
DOI 10.1080/10826076.2017.1388818
Metabolites of Heroin in Several Different Post-mortem Matrices
J Anal Toxicol, 42 (5), 311-320
DOI 10.1093/jat/bky002, PubMed 29409037
Rapid determination of designer benzodiazepines, benzodiazepines, and Z-hypnotics in whole blood using parallel artificial liquid membrane extraction and UHPLC-MS/MS
Anal Bioanal Chem, 410 (20), 4967-4978
DOI 10.1007/s00216-018-1147-y, PubMed 29947895
Electromembrane extraction of substances with weakly basic properties: a fundamental study with benzodiazepines
Bioanalysis, 10 (10), 769-781
DOI 10.4155/bio-2018-0030, PubMed 29771135
Comparative Study of Postmortem Concentrations of Antidepressants in Several Different Matrices
J Anal Toxicol, 42 (7), 446-458
DOI 10.1093/jat/bky030, PubMed 29762694
Publications 2017
Zopiclone concentrations in oral fluid and blood after, administration of therapeutic doses of zopiclone
Forensic Sci Int, 278, 177-183
DOI 10.1016/j.forsciint.2017.07.004, PubMed 28735217
Underestimated impact of novel psychoactive substances: laboratory confirmation of recreational drug toxicity in Oslo, Norway
Clin Toxicol (Phila), 55 (7), 636-644
DOI 10.1080/15563650.2017.1312002, PubMed 28406320
Studies on Para-Methoxymethamphetamine (PMMA) Metabolite Pattern and Influence of CYP2D6 Genetics in Human Liver Microsomes and Authentic Samples from Fatal PMMA Intoxications
Drug Metab Dispos, 45 (12), 1326-1335
DOI 10.1124/dmd.117.077263, PubMed 28978661
Parallel artificial liquid membrane extraction of new psychoactive substances in plasma and whole blood
J Chromatogr B Analyt Technol Biomed Life Sci, 1048, 77-84
DOI 10.1016/j.jchromb.2017.02.010, PubMed 28226266
Efficient discrimination and removal of phospholipids during electromembrane extraction from human plasma samples
Bioanalysis, 9 (8), 631-641
DOI 10.4155/bio-2017-0027, PubMed 28508669
Chapter 101 Screening of Synthetic Cannabinoids
In Handbook of Cannabis and Related Pathologies (Victor R. Preedy, ed.), Academic Press, San Diego, 1, 981-997
DOI 10.1016/B978-0-12-800756-3.00118-6, PublikaID 291, ISBN 978-0-12-800756-3
Publications 2016
Extended Detection of Amphetamine and Methamphetamine in Oral Fluid
Ther Drug Monit, 38 (1), 114-9
DOI 10.1097/FTD.0000000000000248, PubMed 26402425
Parallel artificial liquid membrane extraction as an efficient tool for removal of phospholipids from human plasma
J Pharm Biomed Anal, 129, 229-236
DOI 10.1016/j.jpba.2016.07.011, PubMed 27433988
New psychoactive substances
Tidsskr. Nor. Laegeforen., 136 (8), 714-717
Novel psychoactive substances
Tidsskr Nor Laegeforen, 136 (8), 714-7
DOI 10.4045/tidsskr.15.1278, PubMed 27143461
Pharmacological Effects of a Monoclonal Antibody against 6-Monoacetylmorphine upon Heroin-Induced Locomotor Activity and Pharmacokinetics in Mice
J Pharmacol Exp Ther, 358 (2), 181-9
DOI 10.1124/jpet.116.233510, PubMed 27217591
New drugs right from the online
Tidsskr. Nor. Laegeforen., 136 (8), 721-723
New designer drugs from the web
Tidsskr Nor Laegeforen, 136 (8), 721-3
DOI 10.4045/tidsskr.15.1276, PubMed 27143463
Is toxicity of PMMA (paramethoxymethamphetamine) associated with cytochrome P450 pharmacogenetics?
Forensic Sci Int, 261, 137-47
DOI 10.1016/j.forsciint.2016.02.027, PubMed 26930544
Oral fluid drug analysis in the age of new psychoactive substances
Bioanalysis, 8 (7), 691-710
DOI 10.4155/bio-2015-0027, PubMed 26964619
Publications 2015
Comparison of drugs used by nightclub patrons and criminal offenders in Oslo, Norway
Forensic Sci Int, 265, 1-5
DOI 10.1016/j.forsciint.2015.12.029, PubMed 26826845
Determination of dopamine concentrations in brain extracellular fluid using microdialysis with short sampling intervals, analyzed by ultra high performance liquid chromatography tandem mass spectrometry
J Pharmacol Toxicol Methods, 74, 75-9
DOI 10.1016/j.vascn.2015.06.002, PubMed 26123500
Detection Times of Diazepam, Clonazepam, and Alprazolam in Oral Fluid Collected From Patients Admitted to Detoxification, After High and Repeated Drug Intake
Ther Drug Monit, 37 (4), 451-60
DOI 10.1097/FTD.0000000000000174, PubMed 25549207
Publications 2014
Detection time for THC in oral fluid after frequent cannabis smoking
Ther Drug Monit, 36 (6), 808-14
DOI 10.1097/FTD.0000000000000092, PubMed 24819969
Use of alcohol and drugs among health professionals in Norway: a study using data from questionnaires and samples of oral fluid
J Occup Med Toxicol, 9 (1), 8
DOI 10.1186/1745-6673-9-8, PubMed 24612541
Parallel electromembrane extraction in the 96-well format
Anal Chim Acta, 828, 46-52
DOI 10.1016/j.aca.2014.04.038, PubMed 24845814
A comparison of alcohol and drug use by random motor vehicle drivers in Brazil and Norway
Int J Drug Policy, 25 (3), 393-400
DOI 10.1016/j.drugpo.2014.01.019, PubMed 24613265
Role of 6-monoacetylmorphine in the acute release of striatal dopamine induced by intravenous heroin
Int J Neuropsychopharmacol, 17 (9), 1357-65
DOI 10.1017/S1461145714000169, PubMed 24576415
Concentrations of APINACA, 5F-APINACA, UR-144 and its degradant product in blood samples from six impaired drivers compared to previous reported concentrations of other synthetic cannabinoids
Forensic Sci Int, 246, 98-103
DOI 10.1016/j.forsciint.2014.11.012, PubMed 25485949
Determination of a selection of anti-epileptic drugs and two active metabolites in whole blood by reversed phase UPLC-MS/MS and some examples of application of the method in forensic toxicology cases
Drug Test Anal, 7 (7), 634-44
DOI 10.1002/dta.1733, PubMed 25331692
Very long Detection Times after High and repeated intake of Heroin and Methadone, measured in Oral Fluid
Scand. J. Forensic Sci., 20 (2), 34-41
DOI 10.2478/sjfs-2014-0004
Very long Detection Times after High and repeated intake of Heroin and Methadone, measured in Oral Fluid
Scandinavian Journal of Forensic Science, 20 (2), 34-41
DOI 10.2478/sjfs-2014-0004, PublikaID 292
Publications 2013
Norwegian roadside survey of alcohol and drug use by drivers (2008-2009)
Traffic Inj Prev, 14 (5), 443-52
DOI 10.1080/15389588.2012.728016, PubMed 23697895
Levels of heroin and its metabolites in blood and brain extracellular fluid after i.v. heroin administration to freely moving rats
Br J Pharmacol, 170 (3), 546-56
DOI 10.1111/bph.12305, PubMed 23865556
Comparison of drug concentrations between whole blood and oral fluid
Drug Test Anal, 6 (5), 461-71
DOI 10.1002/dta.1532, PubMed 24039237
A Norwegian study of the suitability of hair samples in epidemiological research of alcohol, nicotine and drug use
J Anal Toxicol, 37 (6), 362-8
DOI 10.1093/jat/bkt038, PubMed 23689070
A Norwegian study of the suitability of hair samples in epidemiological research of alcohol, nicotine and drug use
J Anal Toxicol, 37 (6), 362-8
DOI 10.1093/jat/bkt038 , PublikaID 266
Screening of synthetic cannabinoids in preserved oral fluid by UPLC-MS/MS
Bioanalysis, 5 (18), 2257-68
DOI 10.4155/bio.13.182, PubMed 24053241
Prevalence of synthetic cannabinoids in blood samples from Norwegian drivers suspected of impaired driving during a seven weeks period
Accid Anal Prev, 62, 26-31
DOI 10.1016/j.aap.2013.09.009, PubMed 24129318
Analyses of beverage remains in drug rape cases revealing drug residues--the possibility of contamination from drug concentrated oral fluid or oral cavity contained tablets
J Forensic Sci, 59 (1), 208-10
DOI 10.1111/1556-4029.12270, PubMed 24117495
Publications 2012
Simultaneous measurement of heroin and its metabolites in brain extracellular fluid by microdialysis and ultra performance liquid chromatography tandem mass spectrometry
J Pharmacol Toxicol Methods, 66 (1), 14-21
DOI 10.1016/j.vascn.2012.04.009, PubMed 22561414
Prolonged excretion of 7-aminoclonazepam in urine after repeated ingestion of clonazepam: a case report
Forensic Sci Int, 222 (1-3), e33-5
DOI 10.1016/j.forsciint.2012.06.018, PubMed 22819278
[Effect and occurrence of synthetic cannabinoids]
Tidsskr Nor Laegeforen, 132 (20), 2285-8
DOI 10.4045/tidsskr.12.0471, PubMed 23736196
The PMMA epidemic in Norway: comparison of fatal and non-fatal intoxications
Forensic Sci Int, 219 (1-3), 151-7
DOI 10.1016/j.forsciint.2011.12.014, PubMed 22257968
Detection of drugs of abuse in simultaneously collected oral fluid, urine and blood from Norwegian drug drivers
Forensic Sci Int, 219 (1-3), 165-71
DOI 10.1016/j.forsciint.2012.01.001, PubMed 22284072
Detection of drugs of abuse in simultaneously collected oral fluid, urine and blood from Norwegian drug drivers
Forensic Sci Int, 219 (1-3), 165
PublikaID 265
Publications 2011
Using biological samples in epidemiological research on drugs of abuse
Norsk Epidemiologi, 21 (1), 5-14
PublikaID 293
Electromembrane extraction of stimulating drugs from undiluted whole blood
J Chromatogr A, 1232, 27-36
DOI 10.1016/j.chroma.2011.08.058, PubMed 21899849
Comparison of the stability of stock solutions of drugs of abuse and other drugs stored in a freezer, refrigerator, and at ambient temperature for up to one year
J Anal Toxicol, 35 (8), 583-90
DOI 10.1093/anatox/35.8.583, PubMed 22004679
Drugs of abuse in oral fluid collected by two different sample kits--stability testing and validation using ultra performance tandem mass spectrometry analysis
J Chromatogr B Analyt Technol Biomed Life Sci, 879 (30), 3367-77
DOI 10.1016/j.jchromb.2011.09.002, PubMed 21962269
Drugs of abuse in oral fluid collected by two different sample kits-stability testing and validation using ultra performance tandem mass spectrometry analysis.
J Chromatogr B Analyt Technol Biomed Life Sci, 879 (30), 3367-77
DOI 10.1016/j.jchromb.2011.09.002 , PublikaID 263
Drug screening of whole blood by ultra-performance liquid chromatography-tandem mass spectrometry
J Anal Toxicol, 35 (5), 280-93
DOI 10.1093/anatox/35.5.280, PubMed 21619723
Oral fluid is a viable alternative for monitoring drug abuse: detection of drugs in oral fluid by liquid chromatography-tandem mass spectrometry and comparison to the results from urine samples from patients treated with Methadone or Buprenorphine
J Anal Toxicol, 35 (1), 32-9
DOI 10.1093/anatox/35.1.32, PubMed 21219701
Publications 2010
Comparison of zopiclone concentrations in oral fluid sampled with Intercept(®) oral specimen collection device and Statsure Saliva Sampler™ and concentrations in blood
J Anal Toxicol, 34 (9), 590-3
DOI 10.1093/jat/34.9.590, PubMed 21073813
Comparison of ethanol and other drugs of abuse concentrations in whole blood stored in venoject glass and plastic and venosafe plastic evacuated tubes
J Anal Toxicol, 34 (7), 420-8
DOI 10.1093/jat/34.7.420, PubMed 20822681
Publications 2009
Determination of digoxin and digitoxin in whole blood
J Anal Toxicol, 33 (7), 372-8
DOI 10.1093/jat/33.7.372, PubMed 19796507
Publications 2008
Prevalence of alcohol and drugs among Norwegian motor vehicle drivers: a roadside survey
Accid Anal Prev, 40 (5), 1765-72
DOI 10.1016/j.aap.2008.06.015, PubMed 18760106
Publications 2007
Rapid quantification of buprenorphine-glucuronide and norbuprenorphine-glucuronide in human urine by LC-MS-MS
J Anal Toxicol, 31 (4), 214-9
DOI 10.1093/jat/31.4.214, PubMed 17555645
Publications 2006
Determination of benzodiazepines in human urine using solid-phase extraction and high-performance liquid chromatography-electrospray ionization tandem mass spectrometry
J Anal Toxicol, 30 (1), 31-7
DOI 10.1093/jat/30.1.31, PubMed 16620529
Simultaneous determination of 6 beta-blockers, 3 calcium-channel antagonists, 4 angiotensin-II antagonists and 1 antiarrhythmic drug in post-mortem whole blood by automated solid phase extraction and liquid chromatography mass spectrometry. Method development and robustness testing by experimental design
J Chromatogr B Analyt Technol Biomed Life Sci, 850 (1-2), 147-60
DOI 10.1016/j.jchromb.2006.11.030, PubMed 17175206
Drug screening of preserved oral fluid by liquid chromatography-tandem mass spectrometry
Clin Chem, 53 (2), 300-9
DOI 10.1373/clinchem.2006.074237, PubMed 17158196
Publications 2000
Unimolecular reactions of protonated hydrogen peroxide: A quantum chemical survey
Journal of Physical Chemistry A, 104, 8382-8388
DOI 10.1021/jp000480g, PublikaID 369
Dipolar H-2 activation by H2O
Chemical Communications, 1 (10), 831-832
DOI 10.1039/b001209m, PublikaID 370
Competition between proton transfer and hydride abstraction in chemical ionisation mass spectrometry of ethylamine
International Journal of Mass Spectrometry, 199 (1-3), 91-105
PublikaID 371
Publications 1999
The unimolecular chemistry of protonated hydroxylamine
International Journal of Mass Spectrometry, 185, 231-240
PublikaID 368
Publications 1997
Unimolecular reactions of protonated hydrazine. Reaction mechanisms and dynamics from observation of metastable ion fragmentations and ab initio calculations
International Journal of Mass Spectrometry, 165, 39-47
PublikaID 367
Publications 1995
Loss of H-2 from CH3NH3+, CH3OH2+ and CH3FH+ - Reaction-Mechanisms and Dynamics from Observation of Metastable Ion Fragmentations and Ab-Initio Calculations Reaction-Mechanisms
Europeamn Mass Spectrometry, 1 (2), 121-129
PublikaID 366