Elisabeth Leere Øiestad
- Senior Scientist, Associate Professor; PhD
- +47 23 01 30 66
Publications 2024
An efficient and green method for the analysis of synthetic cathinones in whole blood using 96-well electromembrane extraction and LC-MS/MS
Sustainable Chemistry and Pharmacy, 38, 101494
DOI 10.1016/j.scp.2024.101494, PublikaID 508
On the Surprising Retention Order of Ketamine Analogs Using a Biphenyl Stationary Phase
LCGC Supplements Recent Developments in HPLC, 1, 26–29
DOI 10.56530/lcgc.int.yk4168j2, PublikaID 509
Publications 2021
Electromembrane extraction using deep eutectic solvents as the liquid membrane
Anal. Chim. Acta, 1143, 109-116
DOI 10.1016/j.aca.2020.11.044
Green and sustainable drug analysis-Combining microsampling and microextraction of drugs of abuse
SUSTAIN. CHEM. PHARM., 24, 100517
DOI 10.1016/j.scp.2021.100517
Novel approaches and green sample preparation in bioanalytical protocols
SUSTAIN. CHEM. PHARM., 24, 100559
DOI 10.1016/j.scp.2021.100559
Distribution of tetrahydrocannabinol and cannabidiol in several different postmortem matrices
Forensic Sci.Int., 329, 111082
DOI 10.1016/j.forsciint.2021.111082
Electromembrane extraction of anthracyclines from plasma: Comparison with conventional extraction techniques
Talanta, 223, 121748
DOI 10.1016/j.talanta.2020.121748
Determination of psychoactive drugs in serum using conductive vial electromembrane extraction combined with UHPLC-MS/MS
J. Chromatogr. B, 1183, 122926
DOI 10.1016/j.jchromb.2021.122926
Publications 2020
Electromembrane Extraction with Vitals of Counducting Polymer
LCGCN North America, 38 (8), 435-439
PublikaID 355
Impact of ion balance in electromembrane extraction
Anal. Chim. Acta, 1124, 129-136
DOI 10.1016/j.aca.2020.05.039
Bioanalysis of pharmaceuticals using liquid-phase microextraction combined with liquid chromatography-mass spectrometry
J. Pharm. Biomed. Anal., 189, 113446
DOI 10.1016/j.jpba.2020.113446
Electromembrane extraction of highly polar bases from biological samples - Deeper insight into bis(2-ethylhexyl) phosphate as ionic carrier
Anal. Chim. Acta, 1115, 23-32
DOI 10.1016/j.aca.2020.04.027
Comparison of anticoagulant rodenticide concentrations in liver and feces from apparently healthy red foxes
J. Vet. Diagn. Invest., 32 (4), 1040638720927365-564
DOI 10.1177/1040638720927365
Determination of anticoagulant rodenticides in faeces of exposed dogs and in a healthy dog population
Acta Vet. Scand., 62 (1), 30
DOI 10.1186/s13028-020-00531-5
Publications 2019
Liquid-phase microextraction in 96-well plates - calibration and accurate quantification of pharmaceuticals in human plasma samples
J. Chromatogr. A, 1602, 117-123
DOI 10.1016/j.chroma.2019.06.013
Identification and Assessment of Drug-User Groups Among Nightlife Attendees: Self-Reports, Breathalyzer-Tests and Oral Fluid Drug Tests
Eur. Addict. Res., 25 (2), 93-102
DOI 10.1159/000497318
Detection Time of Oxazepam and Zopiclone in Urine and Oral Fluid after Experimental Oral Dosing
J. Anal. Toxicol., 43 (5), 369-377
DOI 10.1093/jat/bky083
A Monoclonal Antibody against 6-Acetylmorphine Protects Female Mice Offspring from Adverse Behavioral Effects Induced by Prenatal Heroin Exposure
J. Pharmacol. Exp. Ther., 368 (1), 106-115
DOI 10.1124/jpet.118.251504
Interpreting oral fluid drug results in prisoners: monitoring current drug intake and detection times for drugs self-administered prior to detention
Forensic Toxicol., 37 (1), 59-74
DOI 10.1007/s11419-018-0434-9
PREVALENCE OF ANTICOAGULANT RODENTICIDES IN FECES OF WILD RED FOXES (VULPES VULPES) IN NORWAY
J. Wildl. Dis., 55 (4), 834-843
DOI 10.7589/2019-01-027
An Experimental Study of Diazepam and Alprazolam Kinetics in Urine and Oral Fluid Following Single Oral Doses
J. Anal. Toxicol., 43 (2), 104-111
DOI 10.1093/jat/bky062
Electromembrane extraction with solvent modification of the acceptor solution: improved mass transfer of drugs of abuse from human plasma
Bioanalysis, 11 (8), 755-771
DOI 10.4155/bio-2018-0308
Publications 2018
Dried blood spots and parallel artificial liquid membrane extraction-A simple combination of microsampling and microextraction
Anal. Chim. Acta, 1009, 56-64
DOI 10.1016/j.aca.2018.01.024
Separation of isomers of new psychoactive substances and isotope-labeled amphetamines using UHPSFC-MS/MS and UHPLC-MS/MS
J. Liq. Chromatogr. Relat. Technol., 41 (7), 391-400
DOI 10.1080/10826076.2017.1388818
Comparative Study of Postmortem Concentrations of Antidepressants in Several Different Matrices
J. Anal. Toxicol., 42 (7), 446-458
DOI 10.1093/jat/bky030
Metabolites of Heroin in Several Different Post-mortem Matrices
J. Anal. Toxicol., 42 (5), 311-320
DOI 10.1093/jat/bky002
Electromembrane extraction of substances with weakly basic properties: a fundamental study with benzodiazepines
Bioanalysis, 10 (10), 769-781
DOI 10.4155/bio-2018-0030
Rapid determination of designer benzodiazepines, benzodiazepines, and Z-hypnotics in whole blood using parallel artificial liquid membrane extraction and UHPLC-MS/MS
Anal. Bioanal. Chem., 410 (20), 4967-4978
DOI 10.1007/s00216-018-1147-y
Publications 2017
Zopiclone concentrations in oral fluid and blood after, administration of therapeutic doses of zopiclone
Forensic Sci.Int., 278, 177-183
DOI 10.1016/j.forsciint.2017.07.004
Underestimated impact of novel psychoactive substances: laboratory confirmation of recreational drug toxicity in Oslo, Norway
Clin. Toxicol., 55 (7), 636-644
DOI 10.1080/15563650.2017.1312002
Parallel artificial liquid membrane extraction of new psychoactive substances in plasma and whole blood
J. Chromatogr. B, 1048, 77-84
DOI 10.1016/j.jchromb.2017.02.010
Efficient discrimination and removal of phospholipids during electromembrane extraction from human plasma samples
Bioanalysis, 9 (8), 631-641
DOI 10.4155/bio-2017-0027
Studies on Para-Methoxymethamphetamine (PMMA) Metabolite Pattern and Influence of CYP2D6 Genetics in Human Liver Microsomes and Authentic Samples from Fatal PMMA Intoxications
Drug Metab. Dispos., 45 (12), 1326-1335
DOI 10.1124/dmd.117.077263
Chapter 101 Screening of Synthetic Cannabinoids
In Handbook of Cannabis and Related Pathologies (Victor R. Preedy, ed.), Academic Press, San Diego, 1, 981-997
DOI 10.1016/B978-0-12-800756-3.00118-6, PublikaID 291, ISBN 978-0-12-800756-3
Publications 2016
Extended Detection of Amphetamine and Methamphetamine in Oral Fluid
Ther. Drug Monit., 38 (1), 114-119
DOI 10.1097/FTD.0000000000000248
Parallel artificial liquid membrane extraction as an efficient tool for removal of phospholipids from human plasma
J. Pharm. Biomed. Anal., 129, 229-236
DOI 10.1016/j.jpba.2016.07.011
Comparison of drugs used by nightclub patrons and criminal offenders in Oslo, Norway
Forensic Sci.Int., 265, 1-5
DOI 10.1016/j.forsciint.2015.12.029
New psychoactive substances
Tidsskr. Nor. Laegeforen., 136 (8), 714-717
Pharmacological Effects of a Monoclonal Antibody against 6-Monoacetylmorphine upon Heroin-Induced Locomotor Activity and Pharmacokinetics in Mice
J. Pharmacol. Exp. Ther., 358 (2), 181-189
DOI 10.1124/jpet.116.233510
Oral fluid drug analysis in the age of new psychoactive substances
Bioanalysis, 8 (7), 691-710
DOI 10.4155/bio-2015-0027
New drugs right from the online
Tidsskr. Nor. Laegeforen., 136 (8), 721-723
Is toxicity of PMMA (paramethoxymethamphetamine) associated with cytochrome P450 pharmacogenetics?
Forensic Sci.Int., 261, 137-147
DOI 10.1016/j.forsciint.2016.02.027
Publications 2015
Determination of dopamine concentrations in brain extracellular fluid using microdialysis with short sampling intervals, analyzed by ultra high performance liquid chromatography tandem mass spectrometry
J. Pharmacol. Toxicol. Methods, 74, 75-79
DOI 10.1016/j.vascn.2015.06.002
Concentrations of APINACA, 5F-APINACA, UR-144 and its degradant product in blood samples from six impaired drivers compared to previous reported concentrations of other synthetic cannabinoids
Forensic Sci.Int., 246, 98-103
DOI 10.1016/j.forsciint.2014.11.012
Determination of a selection of anti-epileptic drugs and two active metabolites in whole blood by reversed phase UPLC-MS/MS and some examples of application of the method in forensic toxicology cases
Drug Test. Anal., 7 (7), 634-644
DOI 10.1002/dta.1733
Detection Times of Diazepam, Clonazepam, and Alprazolam in Oral Fluid Collected From Patients Admitted to Detoxification, After High and Repeated Drug Intake
Ther. Drug Monit., 37 (4), 451-460
DOI 10.1097/FTD.0000000000000174
Publications 2014
Detection Time for THC in Oral Fluid After Frequent Cannabis Smoking
Ther. Drug Monit., 36 (6), 808-814
DOI 10.1097/FTD.0000000000000092
Use of alcohol and drugs among health professionals in Norway: a study using data from questionnaires and samples of oral fluid
J. Occup. Med. Toxicol., 9, 8
DOI 10.1186/1745-6673-9-8
Parallel electromembrane extraction in the 96-well format
Anal. Chim. Acta, 828, 46-52
DOI 10.1016/j.aca.2014.04.038
A comparison of alcohol and drug use by random motor vehicle drivers in Brazil and Norway
Int. J. Drug Policy, 25 (3), 393-400
DOI 10.1016/j.drugpo.2014.01.019
Role of 6-monoacetylmorphine in the acute release of striatal dopamine induced by intravenous heroin
Int. J. Neuropsychopharmacol., 17 (9), 1357-1365
DOI 10.1017/S1461145714000169
Comparison of drug concentrations between whole blood and oral fluid
Drug Test. Anal., 6 (5), 461-471
DOI 10.1002/dta.1532
Analyses of Beverage Remains in Drug Rape Cases Revealing Drug Residues - The Possibility of Contamination from Drug Concentrated Oral Fluid or Oral Cavity Contained Tablets
J. Forensic Sci., 59 (1), 208-210
DOI 10.1111/1556-4029.12270
Prevalence of synthetic cannabinoids in blood samples from Norwegian drivers suspected of impaired driving during a seven weeks period
Accid. Anal. Prev., 62, 26-31
DOI 10.1016/j.aap.2013.09.009
Very long Detection Times after High and repeated intake of Heroin and Methadone, measured in Oral Fluid
Scand. J. Forensic Sci., 20 (2), 34-41
DOI 10.2478/sjfs-2014-0004
Very long Detection Times after High and repeated intake of Heroin and Methadone, measured in Oral Fluid
Scandinavian Journal of Forensic Science, 20 (2), 34-41
DOI 10.2478/sjfs-2014-0004, PublikaID 292
Publications 2013
Norwegian Roadside Survey of Alcohol and Drug Use by Drivers (2008-2009)
Traffic Inj. Prev., 14 (5), 443-452
DOI 10.1080/15389588.2012.728016
Levels of heroin and its metabolites in blood and brain extracellular fluid after i.v. heroin administration to freely moving rats
Br. J. Pharmacol., 170 (3), 546-556
DOI 10.1111/bph.12305
A Norwegian Study of the Suitability of Hair Samples in Epidemiological Research of Alcohol, Nicotine and Drug Use
J. Anal. Toxicol., 37 (6), 362-368
DOI 10.1093/jat/bkt038
A Norwegian study of the suitability of hair samples in epidemiological research of alcohol, nicotine and drug use
J Anal Toxicol, 37 (6), 362-8
DOI 10.1093/jat/bkt038 , PublikaID 266
Screening of synthetic cannabinoids in preserved oral fluid by UPLC-MS/MS
Bioanalysis, 5 (18), 2257-2268
DOI 10.4155/bio.13.182
Publications 2012
Simultaneous measurement of heroin and its metabolites in brain extracellular fluid by microdialysis and ultra performance liquid chromatography tandem mass spectrometry
J. Pharmacol. Toxicol. Methods, 66 (1), 14-21
DOI 10.1016/j.vascn.2012.04.009
Electromembrane extraction of stimulating drugs from undiluted whole blood
J. Chromatogr. A, 1232, 27-36
DOI 10.1016/j.chroma.2011.08.058
Prolonged excretion of 7-aminoclonazepam in urine after repeated ingestion of clonazepam: A case report
Forensic Sci.Int., 222 (1-3), E33-E35
DOI 10.1016/j.forsciint.2012.06.018
The PMMA epidemic in Norway: Comparison of fatal and non-fatal intoxications
Forensic Sci.Int., 219 (1-3)
DOI 10.1016/j.forsciint.2011.12.014
Detection of drugs of abuse in simultaneously collected oral fluid, urine and blood from Norwegian drug drivers
Forensic Sci.Int., 219 (1-3)
DOI 10.1016/j.forsciint.2012.01.001
Detection of drugs of abuse in simultaneously collected oral fluid, urine and blood from Norwegian drug drivers
Forensic Sci Int, 219 (1-3), 165
PublikaID 265
Publications 2011
Using biological samples in epidemiological research on drugs of abuse
Norsk Epidemiologi, 21 (1), 5-14
PublikaID 293
Comparison of the Stability of Stock Solutions of Drugs of Abuse and Other Drugs Stored in a Freezer, Refrigerator, and at Ambient Temperature for Up to One Year
J. Anal. Toxicol., 35 (8), 583-590
DOI 10.1093/anatox/35.8.583
Drugs of abuse in oral fluid collected by two different sample kits - Stability testing and validation using ultra performance tandem mass spectrometry analysis
J. Chromatogr. B, 879 (30), 3367-3377
DOI 10.1016/j.jchromb.2011.09.002
Drugs of abuse in oral fluid collected by two different sample kits-stability testing and validation using ultra performance tandem mass spectrometry analysis.
J Chromatogr B Analyt Technol Biomed Life Sci, 879 (30), 3367-77
DOI 10.1016/j.jchromb.2011.09.002 , PublikaID 263
Drug Screening of Whole Blood by Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry
J. Anal. Toxicol., 35 (5), 280-293
DOI 10.1093/anatox/35.5.280
Oral Fluid is a Viable Alternative for Monitoring Drug Abuse: Detection of Drugs in Oral Fluid by Liquid Chromatography-Tandem Mass Spectrometry and Comparison to the Results from Urine Samples from Patients Treated with Methadone or Buprenorphine
J. Anal. Toxicol., 35 (1), 32-39
DOI 10.1093/anatox/35.1.32
Publications 2010
Comparison of Zopiclone Concentrations in Oral Fluid Sampled with Intercept (R) Oral Specimen Collection Device and Statsure Saliva Sampler (TM) and Concentrations in Blood
J. Anal. Toxicol., 34 (9), 590-593
DOI 10.1093/jat/34.9.590
Comparison of Ethanol and Other Drugs of Abuse Concentrations in Whole Blood Stored in Venoject (R) Glass and Plastic and Venosafe (TM) Plastic Evacuated Tubes
J. Anal. Toxicol., 34 (7), 420-428
DOI 10.1093/jat/34.7.420
Publications 2009
Determination of Digoxin and Digitoxin in Whole Blood
J. Anal. Toxicol., 33 (7), 372-378
DOI 10.1093/jat/33.7.372
Publications 2008
Prevalence of alcohol and drugs among Norwegian motor vehicle drivers: A roadside survey
Accid. Anal. Prev., 40 (5), 1765-1772
DOI 10.1016/j.aap.2008.06.015
Publications 2007
Rapid quantification of buprenorphine-glucuronide and norbuprenorphine-glucuronide in human urine by LC-MS-MS
J. Anal. Toxicol., 31 (4), 214-219
DOI 10.1093/jat/31.4.214
Simultaneous determination of 6 beta-blockers, 3 calcium-channel antagonists, 4 angiotensin-II antagonists and 1 antiarrhytmic drug in post-mortem whole blood by automated solid phase extraction and liquid chromatography mass spectrometry - Method development and robustness testing by experimental design
J. Chromatogr. B, 850 (1-2), 147-160
DOI 10.1016/j.jchromb.2006.11.030
Drug screening of preserved oral fluid by liquid chromatography-tandem mass spectrometry
Clin. Chem., 53 (2), 300-309
DOI 10.1373/clinchem.2006.074237
Publications 2000
Unimolecular reactions of protonated hydrogen peroxide: A quantum chemical survey
Journal of Physical Chemistry A, 104, 8382-8388
DOI 10.1021/jp000480g, PublikaID 369
Dipolar H-2 activation by H2O
Chemical Communications, 1 (10), 831-832
DOI 10.1039/b001209m, PublikaID 370
Competition between proton transfer and hydride abstraction in chemical ionisation mass spectrometry of ethylamine
International Journal of Mass Spectrometry, 199 (1-3), 91-105
PublikaID 371
Publications 1999
The unimolecular chemistry of protonated hydroxylamine
International Journal of Mass Spectrometry, 185, 231-240
PublikaID 368
Publications 1997
Unimolecular reactions of protonated hydrazine. Reaction mechanisms and dynamics from observation of metastable ion fragmentations and ab initio calculations
International Journal of Mass Spectrometry, 165, 39-47
PublikaID 367
Publications 1995
Loss of H-2 from CH3NH3+, CH3OH2+ and CH3FH+ - Reaction-Mechanisms and Dynamics from Observation of Metastable Ion Fragmentations and Ab-Initio Calculations Reaction-Mechanisms
Europeamn Mass Spectrometry, 1 (2), 121-129
PublikaID 366