Publications 2024

Bråtveit M, Van Parys A, Olsen T, Strand E, Marienborg I, Laupsa-Borge J, Haugsgjerd TR, McCann A, Dhar I, Ueland PM, Dierkes J, Dankel SN, Nygård OK, Lysne V (2024)
Association between dietary macronutrient composition and plasma one-carbon metabolites and B-vitamin cofactors in patients with stable angina pectoris
Br J Nutr, 131 (10), 1678-1690
DOI 10.1017/S0007114524000473, PubMed 38361451

Jeevanathan J, Blom SM, Olsen T, Holven KB, Arnesen EK, Trydal T, Nordestgaard BG, Sovershaev M, Chen Y, Retterstøl K, Christensen JJ (2024)
Real-world impact of transitioning from one lipoprotein(a) assay to another in a clinical setting
Am J Prev Cardiol, 19, 100726
DOI 10.1016/j.ajpc.2024.100726, PubMed 39286651

Karlsson C, Johnson LK, Greasley PJ, Retterstøl K, Hedberg J, Hall M, Hawker N, Robertsen I, Havsol J, Hertel JK, Sandbu R, Skovlund E, Olsen T, Christensen H, Jansson-Löfmark R, Andersson S, Åsberg A, Hjelmesæth J (2024)
Gastric Bypass vs Diet and Cardiovascular Risk Factors: A Nonrandomized Controlled Trial
JAMA Surg, 159 (9), 971-980
DOI 10.1001/jamasurg.2024.2162, PubMed 38959017

Lee-Ødegård S, Hjorth M, Olsen T, Moen GH, Daubney E, Evans DM, Hevener AL, Lusis AJ, Zhou M, Seldin MM, Allayee H, Hilser J, Viken JK, Gulseth H, Norheim F, Drevon CA, Birkeland KI (2024)
Serum proteomic profiling of physical activity reveals CD300LG as a novel exerkine with a potential causal link to glucose homeostasis
Elife, 13
DOI 10.7554/eLife.96535, PubMed 39190027

Majtan T, Olsen T, Sokolova J, Krijt J, Křížková M, Ida T, Ditrói T, Hansikova H, Vit O, Petrak J, Kuchař L, Kruger WD, Nagy P, Akaike T, Kožich V (2024)
Deciphering pathophysiological mechanisms underlying cystathionine beta-synthase-deficient homocystinuria using targeted metabolomics, liver proteomics, sphingolipidomics and analysis of mitochondrial function
Redox Biol, 73, 103222
DOI 10.1016/j.redox.2024.103222, PubMed 38843767

Olsen T, Elshorbagy A, Stolt E, Åsberg A, Zaré HK, Bastani NE, Refsum H, Retterstøl K, Vinknes KJ (2024)
Acute effects of oral mesna administration on the full amino acid profile and 3-methylhistidine: secondary results from the CYLOB dose-finding study
Amino Acids, 56 (1), 39
DOI 10.1007/s00726-024-03398-2, PubMed 38844567

Olsen T, Refsum H, Eiser AR (2024)
Hyperhomocysteinemia Is Associated With a Myriad of Age-Related Illnesses: A Potential Role for Metal Toxicity
Mayo Clin Proc, 99 (9), 1362-1368
DOI 10.1016/j.mayocp.2024.04.016, PubMed 38935017

Olsen T, Stolt E, Øvrebø B, Elshorbagy A, Tore EC, Lee-Ødegård S, Troensegaard H, Johannessen H, Doeland B, Vo AAD, Dahl AF, Svendsen K, Thoresen M, Refsum H, Rising R, Barvíková K, van Greevenbroek M, Kožich V, Retterstøl K, Vinknes KJ (2024)
Dietary sulfur amino acid restriction in humans with overweight and obesity: a translational randomized controlled trial
J Transl Med, 22 (1), 40
DOI 10.1186/s12967-023-04833-w, PubMed 38195568

Olsen T, Vinknes KJ, Barvíková K, Stolt E, Lee-Ødegård S, Troensegaard H, Johannessen H, Elshorbagy A, Sokolová J, Krijt J, Křížková M, Ditrói T, Nagy P, Øvrebø B, Refsum H, Thoresen M, Retterstøl K, Kožich V (2024)
Dietary sulfur amino acid restriction in humans with overweight and obesity: Evidence of an altered plasma and urine sulfurome, and a novel metabolic signature that correlates with loss of fat mass and adipose tissue gene expression
Redox Biol, 73, 103192
DOI 10.1016/j.redox.2024.103192, PubMed 38776754

Viken JK, Olsen T, Drevon CA, Hjorth M, Birkeland KI, Norheim F, Lee-Ødegård S (2024)
Intra-Individual Variations in How Insulin Sensitivity Responds to Long-Term Exercise: Predictions by Machine Learning Based on Large-Scale Serum Proteomics
Metabolites, 14 (6)
DOI 10.3390/metabo14060335, PubMed 38921470

Publications 2023

Dhar I, Lysne V, Ulvik A, Svingen GFT, Pedersen ER, Bjørnestad EØ, Olsen T, Borsholm R, Laupsa-Borge J, Ueland PM, Tell GS, Berge RK, Mellgren G, Bønaa KH, Nygård OK (2023)
Plasma methylmalonic acid predicts risk of acute myocardial infarction and mortality in patients with coronary heart disease: A prospective 2-cohort study
J Intern Med, 293 (4), 508-519
DOI 10.1111/joim.13610, PubMed 36682040

Elshorbagy A, Bastani NE, Lee-Ødegård S, Øvrebø B, Haj-Yasein N, Svendsen K, Turner C, Refsum H, Vinknes KJ, Olsen T (2023)
Correction to: The association of fasting plasma thiol fractions with body fat compartments, biomarker profile, and adipose tissue gene expression
Amino Acids, 55 (4), 547-548
DOI 10.1007/s00726-023-03244-x, PubMed 36795350

Henriksen HB, Henriksen C, de Sousa ARS, Alavi DT, Augestad EMS, Rising R, Dörner R, Hägele FA, Bosy-Westphal A, Blomhoff R, Ulven SM, Olsen T (2023)
Validity and reproducibility of a whole-room indirect calorimeter for the estimation of VO₂ , VCO₂ , and resting metabolic rate
Physiol Rep, 11 (7), e15658
DOI 10.14814/phy2.15658, PubMed 37020398

Moore TM, Lee S, Olsen T, Morselli M, Strumwasser AR, Lin AJ, Zhou Z, Abrishami A, Garcia SM, Bribiesca J, Cory K, Whitney K, Ho T, Ho T, Lee JL, Rucker DH, Nguyen CQA, Anand ATS, Yackly A, Mendoza LQ, Leyva BK, Aliman C, Artiga DJ, Meng Y, Charugundla S et al. (2023)
Conserved multi-tissue transcriptomic adaptations to exercise training in humans and mice
Cell Rep, 42 (5), 112499
DOI 10.1016/j.celrep.2023.112499, PubMed 37178122

Olsen T, Lerner UH (2023)
Vitamin A - a scoping review for Nordic nutrition Recommendations 2023
Food Nutr Res, 67
DOI 10.29219/fnr.v67.10229, PubMed 38686175

Tore EC, Eussen SJPM, Bastani NE, Dagnelie PC, Elshorbagy AK, Grootswagers P, Kožich V, Olsen T, Refsum H, Retterstøl K, Stehouwer CD, Stolt ETK, Vinknes KJ, van Greevenbroek MMJ (2023)
The Associations of Habitual Intake of Sulfur Amino Acids, Proteins and Diet Quality with Plasma Sulfur Amino Acid Concentrations: The Maastricht Study
J Nutr, 153 (7), 2027-2040
DOI 10.1016/j.tjnut.2023.05.008, PubMed 37164267

Van Parys A, Sæle J, Puaschitz NG, Anfinsen ÅM, Karlsson T, Olsen T, Haugsgjerd TR, Vinknes KJ, Holven KB, Dierkes J, Nygård OK, Lysne V (2023)
The association between dairy intake and risk of cardiovascular disease and mortality in patients with stable angina pectoris
Eur J Prev Cardiol, 30 (3), 219-229
DOI 10.1093/eurjpc/zwac217, PubMed 36134600

Vinknes KJ, Olsen T, Zaré HK, Bastani NE, Stolt E, Dahl AF, Cox RD, Refsum H, Retterstøl K, Åsberg A, Elshorbagy A (2023)
Cysteine-lowering treatment with mesna against obesity: Proof of concept and results from a human phase I, dose-finding study
Diabetes Obes Metab, 25 (11), 3161-3170
DOI 10.1111/dom.15210, PubMed 37435697

Publications 2022

Dhar I, Svingen GFT, Olsen T, Lysne V, Bjørnestad EØ, Ueland PM, Nygård OK (2022)
β-blocker use and risk of all-cause mortality in patients with coronary heart disease: effect modification by serum vitamin A
Eur J Prev Cardiol, 28 (17), 1897-1902
DOI 10.1093/eurjpc/zwaa158, PubMed 33709106

Doncheva AI, Romero S, Ramirez-Garrastacho M, Lee S, Kolnes KJ, Tangen DS, Olsen T, Drevon CA, Llorente A, Dalen KT, Hjorth M (2022)
Extracellular vesicles and microRNAs are altered in response to exercise, insulin sensitivity and overweight
Acta Physiol (Oxf), 236 (4), e13862
DOI 10.1111/apha.13862, PubMed 36377504

Dörner R, Hägele FA, Koop J, Rising R, Foerster T, Olsen T, Hasler M, Müller MJ, Bosy-Westphal A (2022)
Validation of energy expenditure and macronutrient oxidation measured by two new whole-room indirect calorimeters
Obesity (Silver Spring), 30 (9), 1796-1805
DOI 10.1002/oby.23527, PubMed 35927795

Elshorbagy A, Bastani NE, Lee-Ødegård S, Øvrebø B, Haj-Yasein N, Svendsen K, Turner C, Refsum H, Vinknes KJ, Olsen T (2022)
The association of fasting plasma thiol fractions with body fat compartments, biomarker profile, and adipose tissue gene expression
Amino Acids, 55 (3), 313-323
DOI 10.1007/s00726-022-03229-2, PubMed 36542145

Hustad KS, Ottestad I, Olsen T, Sæther T, Ulven SM, Holven KB (2022)
Salmon fish protein supplement increases serum vitamin B12 and selenium concentrations: secondary analysis of a randomised controlled trial
Eur J Nutr, 61 (6), 3085-3093
DOI 10.1007/s00394-022-02857-4, PubMed 35362766

Lee-Ødegård S, Olsen T, Norheim F, Drevon CA, Birkeland KI (2022)
Potential Mechanisms for How Long-Term Physical Activity May Reduce Insulin Resistance
Metabolites, 12 (3)
DOI 10.3390/metabo12030208, PubMed 35323652

Nichenametla SN, Mattocks DAL, Cooke D, Midya V, Malloy VL, Mansilla W, Øvrebø B, Turner C, Bastani NE, Sokolová J, Pavlíková M, Richie JP, Shoveller AK, Refsum H, Olsen T, Vinknes KJ, Kožich V, Ables GP (2022)
Cysteine restriction-specific effects of sulfur amino acid restriction on lipid metabolism
Aging Cell, 21 (12), e13739
DOI 10.1111/acel.13739, PubMed 36403077

Svendsen K, Olsen T, Vinknes KJ, Mundal LJ, Holven KB, Bogsrud MP, Leren TP, Igland J, Retterstøl K (2022)
Risk of stroke in genetically verified familial hypercholesterolemia: A prospective matched cohort study
Atherosclerosis, 358, 34-40
DOI 10.1016/j.atherosclerosis.2022.08.015, PubMed 36084445

Svendsen K, Vinknes KJ, Retterstøl K, Olsen T (2022)
Why we can probably trust public policy dietary guidelines for prevention
Eur J Prev Cardiol, 29 (6), e209-e210
DOI 10.1093/eurjpc/zwaa008, PubMed 33624034

Tore EC, Elshorbagy AK, Bakers FCH, Brouwers MCGJ, Dagnelie PC, Eussen SJPM, Jansen JFA, Kooi ME, Kusters YHAM, Meex SJR, Olsen T, Refsum H, Retterstøl K, Schalkwijk CG, Stehouwer CDA, Vinknes KJ, van Greevenbroek MMJ (2022)
Associations between plasma sulfur amino acids and specific fat depots in two independent cohorts: CODAM and The Maastricht Study
Eur J Nutr, 62 (2), 891-904
DOI 10.1007/s00394-022-03041-4, PubMed 36322288

Publications 2021

Matre ÅO, Van Parys A, Olsen T, Haugsgjerd TR, Baravelli CM, Nygård O, Dierkes J, Lysne V (2021)
The Association of Meat Intake With All-Cause Mortality and Acute Myocardial Infarction Is Age-Dependent in Patients With Stable Angina Pectoris
Front Nutr, 8, 642612
DOI 10.3389/fnut.2021.642612, PubMed 33748176

Olsen T, Øvrebø B, Turner C, Bastani NE, Refsum H, Vinknes KJ (2021)
Effects of short-term methionine and cysteine restriction and enrichment with polyunsaturated fatty acids on oral glucose tolerance, plasma amino acids, fatty acids, lactate and pyruvate: results from a pilot study
BMC Res Notes, 14 (1), 43
DOI 10.1186/s13104-021-05463-5, PubMed 33531059

Stolt E, Olsen T, Elshorbagy A, Kožich V, van Greevenbroek M, Øvrebø B, Thoresen M, Refsum H, Retterstøl K, Vinknes KJ (2021)
Sulfur amino acid restriction, energy metabolism and obesity: a study protocol of an 8-week randomized controlled dietary intervention with whole foods and amino acid supplements
J Transl Med, 19 (1), 153
DOI 10.1186/s12967-021-02824-3, PubMed 33858441

Van Parys A, Karlsson T, Vinknes KJ, Olsen T, Øyen J, Dierkes J, Nygård O, Lysne V (2021)
Food Sources Contributing to Intake of Choline and Individual Choline Forms in a Norwegian Cohort of Patients With Stable Angina Pectoris
Front Nutr, 8, 676026
DOI 10.3389/fnut.2021.676026, PubMed 34055860

Publications 2020

Dhar I, Siddique S, R Pedersen E, F T Svingen G, Lysne V, Olsen T, Nilsen DW, Nordrehaug JE, Midttun Ø, M Ueland P, S Tell G, K Nygård O (2020)
Lipid parameters and vitamin A modify cardiovascular risk prediction by plasma neopterin
Heart, 106 (14), 1073-1079
DOI 10.1136/heartjnl-2019-316165, PubMed 32398245

Lee S, Gulseth HL, Langleite TM, Norheim F, Olsen T, Refsum H, Jensen J, Birkeland KI, Drevon CA (2020)
Branched-chain amino acid metabolism, insulin sensitivity and liver fat response to exercise training in sedentary dysglycaemic and normoglycaemic men
Diabetologia, 64 (2), 410-423
DOI 10.1007/s00125-020-05296-0, PubMed 33123769

Olsen T, Blomhoff R (2020)
Retinol, Retinoic Acid, and Retinol-Binding Protein 4 are Differentially Associated with Cardiovascular Disease, Type 2 Diabetes, and Obesity: An Overview of Human Studies
Adv Nutr, 11 (3), 644-666
DOI 10.1093/advances/nmz131, PubMed 31868199

Olsen T, Sollie O, Nurk E, Turner C, Jernerén F, Ivy JL, Vinknes KJ, Clauss M, Refsum H, Jensen J (2020)
Exhaustive Exercise and Post-exercise Protein Plus Carbohydrate Supplementation Affect Plasma and Urine Concentrations of Sulfur Amino Acids, the Ratio of Methionine to Homocysteine and Glutathione in Elite Male Cyclists
Front Physiol, 11, 609335
DOI 10.3389/fphys.2020.609335, PubMed 33384615

Olsen T, Turner C, Øvrebø B, Bastani NE, Refsum H, Vinknes KJ (2020)
Postprandial effects of a meal low in sulfur amino acids and high in polyunsaturated fatty acids compared to a meal high in sulfur amino acids and saturated fatty acids on stearoyl CoA-desaturase indices and plasma sulfur amino acids: a pilot study
BMC Res Notes, 13 (1), 379
DOI 10.1186/s13104-020-05222-y, PubMed 32778150

Olsen T, Øvrebø B, Haj-Yasein N, Lee S, Svendsen K, Hjorth M, Bastani NE, Norheim F, Drevon CA, Refsum H, Vinknes KJ (2020)
Effects of dietary methionine and cysteine restriction on plasma biomarkers, serum fibroblast growth factor 21, and adipose tissue gene expression in women with overweight or obesity: a double-blind randomized controlled pilot study
J Transl Med, 18 (1), 122
DOI 10.1186/s12967-020-02288-x, PubMed 32160926

Svendsen K, Olsen T, Nordstrand Rusvik TC, Ulven SM, Holven KB, Retterstøl K, Telle-Hansen VH (2020)
Fatty acid profile and estimated desaturase activities in whole blood are associated with metabolic health
Lipids Health Dis, 19 (1), 102
DOI 10.1186/s12944-020-01282-y, PubMed 32438926

Publications 2019

Koivisto AE, Olsen T, Paur I, Paulsen G, Bastani NE, Garthe I, Raastad T, Matthews J, Blomhoff R, Bøhn SK (2019)
Effects of antioxidant-rich foods on altitude-induced oxidative stress and inflammation in elite endurance athletes: A randomized controlled trial
PLoS One, 14 (6), e0217895
DOI 10.1371/journal.pone.0217895, PubMed 31194785

Olsen T, Vinknes KJ, Blomhoff R, Lysne V, Midttun Ø, Dhar I, Ueland PM, Svingen GFT, Pedersen EKR, Drevon CA, Refsum H, Nygård OK (2019)
Creatinine, total cysteine and uric acid are associated with serum retinol in patients with cardiovascular disease
Eur J Nutr, 59 (6), 2383-2393
DOI 10.1007/s00394-019-02086-2, PubMed 31502058

Publications 2018

Lee S, Olsen T, Vinknes KJ, Refsum H, Gulseth HL, Birkeland KI, Drevon CA (2018)
Plasma Sulphur-Containing Amino Acids, Physical Exercise and Insulin Sensitivity in Overweight Dysglycemic and Normal Weight Normoglycemic Men
Nutrients, 11 (1)
DOI 10.3390/nu11010010, PubMed 30577516

Olsen T, Vinknes KJ, Svingen GF, Pedersen ER, Dhar I, Tell GS, Blomhoff R, Ueland PM, Midttun Ø, Refsum H, Nygård OK (2018)
The risk association of plasma total homocysteine with acute myocardial infarction is modified by serum vitamin A
Eur J Prev Cardiol, 25 (15), 1612-1620
DOI 10.1177/2047487318788587, PubMed 30014716

Olsen T, Øvrebø B, Turner C, Bastani NE, Refsum H, Vinknes KJ (2018)
Combining Dietary Sulfur Amino Acid Restriction with Polyunsaturated Fatty Acid Intake in Humans: A Randomized Controlled Pilot Trial
Nutrients, 10 (12)
DOI 10.3390/nu10121822, PubMed 30477080

Publications 2017

Olsen T, Vinknes KJ, Svingen GFT, Pedersen ER, Tell GS, Blomhoff R, Drevon CA, Ueland PM, Midttun Ø, Refsum H, Nygård OK (2017)
Cardiovascular disease risk associated with serum apolipoprotein B is modified by serum vitamin A
Atherosclerosis, 265, 325-330
DOI 10.1016/j.atherosclerosis.2017.07.020, PubMed 28774484

Strand E, Pedersen ER, Svingen GF, Olsen T, Bjørndal B, Karlsson T, Dierkes J, Njølstad PR, Mellgren G, Tell GS, Berge RK, Svardal A, Nygård O (2017)
Serum Acylcarnitines and Risk of Cardiovascular Death and Acute Myocardial Infarction in Patients With Stable Angina Pectoris
J Am Heart Assoc, 6 (2)
DOI 10.1161/JAHA.116.003620, PubMed 28159823

Publications 2016

Lysne V, Strand E, Svingen GF, Bjørndal B, Pedersen ER, Midttun Ø, Olsen T, Ueland PM, Berge RK, Nygård O (2016)
Peroxisome Proliferator-Activated Receptor Activation is Associated with Altered Plasma One-Carbon Metabolites and B-Vitamin Status in Rats
Nutrients, 8 (1)
DOI 10.3390/nu8010026, PubMed 26742069