Sachin Singh

  • Proteomics Data Analyst; PhD
  • +47230 73807

Sachin started working as head engineer in Proteomics facility in November 2019. He received PhD from University of Karlsruhe Germany in 2015. His PhD was on deciphering in vivo proteome and transcriptome changes over time upon inflammation in zebrafish. Soon after his PhD, He received scientia fellow’s post-doctorate research fellowship (2015-17) to move University of Oslo. He has expertise in Proteomics, PTM-proteomics, Pathway analysis (Meta-Core), R biconductors. He has keen interest in proteomic method development and bioinformatics.


Publications:

High Throughput Chemical Screening Reveals Multiple Regulatory Proteins on FOXA1 in Breast Cancer Cell Lines.
Wang S, Singh SK, Katika MR, Lopez-Aviles S, Hurtado A.
Int J Mol Sci. 2018 Dec 19;19(12). pii: E4123. doi: 10.3390/ijms19124123.
PMID: 30572598

Proximity Labeling by a Recombinant APEX2-FGF1 Fusion Protein Reveals Interaction of FGF1 with the Proteoglycans CD44 and CSPG4.
Zhen Y, Haugsten EM, Singh SK, Wesche J.
Biochemistry. 2018 Jul 3;57(26):3807-3816. doi: 10.1021/acs.biochem.8b00120. Epub 2018 Jun 13.
PMID:29812912

CTCF modulates Estrogen Receptor function through specific chromatin and nuclear matrix interactions.
Fiorito E, Sharma Y, Gilfillan S, Wang S, Singh SK, Satheesh SV, Katika MR, Urbanucci A, Thiede B, Mills IG, Hurtado A.
Nucleic Acids Res. 2016 Dec 15;44(22):10588-10602. Epub 2016 Sep 15.
PMID: 27638884

Proteomic and gene expression analysis of zebrafish brain undergoing continuous light/dark stress.
Purushothaman S, Saxena S, Meghah V, Meena Lakshmi MG, Singh SK, Brahmendra Swamy CV, Idris MM.
J Sleep Res. 2015 Aug;24(4):458-65. doi: 10.1111/jsr.12287. Epub 2015 Feb 27.
PMID:  25726855

Array tomography: characterizing FAC-sorted populations of zebrafish immune cells by their 3D ultrastructure.
Wacker I, Chockley P, Bartels C, Spomer W, Hofmann A, Gengenbach U, Singh S, Thaler M, Grabher C, Schröder RR.
J Microsc. 2015 Aug;259(2):105-113. doi: 10.1111/jmi.12223. Epub 2015 Jan 21.
PMID: 25611576

Proteome dynamics in neutrophils of adult zebrafish upon chemically-induced inflammation.
Singh SK, Aravamudhan S, Armant O, Krüger M, Grabher C.
Fish Shellfish Immunol. 2014 Sep;40(1):217-24. doi: 10.1016/j.fsi.2014.06.035. Epub 2014 Jul 8.
PMID: 25014315

Proteome mapping of adult zebrafish marrow neutrophils reveals partial cross species conservation to humanperipheral neutrophils.
Singh SK, Sethi S, Aravamudhan S, Krüger M, Grabher C.
PLoS One. 2013 Sep 3;8(9):e73998. doi: 10.1371/journal.pone.0073998. eCollection 2013.
PMID: 24019943

Proteome map of the neural complex of the tunicate Ciona intestinalis, the closest living relative to vertebrates.
Saxena S, Dupont S, Meghah V, Lakshmi MG, Singh SK, Swamy CV, Idris MM.
Proteomics. 2013 Mar;13(5):860-5. doi: 10.1002/pmic.201200148. Epub 2013 Jan 30.
PMID:23300126

Proteomic analysis of zebrafish caudal fin regeneration.
Saxena S, Singh SK, Lakshmi MG, Meghah V, Bhatti B, Swamy CV, Sundaram CS, Idris MM.
Mol Cell Proteomics. 2012 Jun;11(6):M111.014118. doi: 10.1074/mcp.M111.014118. Epub 2012 Jan 25.
PMID:22278371

Hydrogen peroxide in inflammation: messenger, guide, and assassin.
Wittmann C, Chockley P, Singh SK, Pase L, Lieschke GJ, Grabher C.
Adv Hematol. 2012;2012:541471. doi: 10.1155/2012/541471. Epub 2012 Jun 12.
PMID: 22737171

Proteome profile of zebrafish Danio rerio olfactory bulb based on two-dimensional gel electrophoresis matrix-assisted laser desorption/ionization MS/MS analysis.
Singh SK, Saxena S, Meena Lakshmi MG, Saxena P, Idris MM.
Zebrafish. 2011 Dec;8(4):183-9. doi: 10.1089/zeb.2011.0711.
PMID:22181661

Proteome profile of zebrafish kidney.
Saxena S, Singh SK, Lakshmi MG, Meghah V, Sundaram CS, Swamy CV, Idris MM.
J Proteomics. 2011 Nov 18;74(12):2937-47. doi: 10.1016/j.jprot.2011.07.021. Epub 2011 Aug 4.
PMID: 21839869

Proteomic profile of zebrafish brain based on two-dimensional gel electrophoresis matrix-assisted laser desorption/ionization MS/MS analysis.
Singh SK, Sundaram CS, Shanbhag S, Idris MM.
Zebrafish. 2010 Jun;7(2):169-77. doi: 10.1089/zeb.2010.0657.
PMID: 20528263

 
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