Pitt Niehusmann
- Consultant; PhD
- +47 23 07 15 03
Publications 2024
The impact of cancer patient pathway on timing of radiotherapy and survival: a cohort study in glioblastoma patients
J Neurooncol, 169 (1), 137-145
DOI 10.1007/s11060-024-04709-z, PubMed 38762830
[Raising the quality of cancer treatment]
Tidsskr Nor Laegeforen, 144 (1)
DOI 10.4045/tidsskr.23.0740, PubMed 38258713
Desmoplastic non-infantile ganglioglioma mimicking diffuse leptomeningeal glioneuronal tumor: precision diagnostics and therapeutic implications
Acta Oncol, 63, 392-394
DOI 10.2340/1651-226X.2024.31720, PubMed 38779936
IMPRESS-Norway: improving public cancer care by implementing precision medicine in Norway; inclusion rates and preliminary results
Acta Oncol, 63, 379-384
DOI 10.2340/1651-226X.2024.28322, PubMed 38779911
Lack of inflammation or immune response in cyst tissue of patients with symptomatic non-hydrocephalic pineal cysts
J Neurol Sci, 462, 123111
DOI 10.1016/j.jns.2024.123111, PubMed 38943895
Stable glioma incidence and increased patient survival over the past two decades in Norway: a nationwide registry-based cohort study
Acta Oncol, 63, 83-94
DOI 10.2340/1651-226X.2024.24970, PubMed 38501768
CNS tumors with PLAGL1-fusion: beyond ZFTA and YAP1 in the genetic spectrum of supratentorial ependymomas
Acta Neuropathol Commun, 12 (1), 55
DOI 10.1186/s40478-023-01695-7, PubMed 38581034
Publications 2023
Incidence and outcome of pseudoprogression after radiation therapy in glioblastoma patients: A cohort study
Neurooncol Pract, 11 (1), 36-45
DOI 10.1093/nop/npad063, PubMed 38222046
Astrocytoma (CNS WHO grade 4), IDH-mutant with co-occurrence of BRAF p.V600E mutation, and homozygous loss of CDKN2A
Neuropathology, 43 (5), 385-390
DOI 10.1111/neup.12895, PubMed 36754566
Publications 2022
Pediatric high-grade gliomas and the WHO CNS Tumor Classification-Perspectives of pediatric neuro-oncologists and neuropathologists in light of recent updates
Neurooncol Adv, 4 (1), vdac077
DOI 10.1093/noajnl/vdac077, PubMed 35733513
Pro-inflammatory cytokines in cystic glioblastoma: A quantitative study with a comparison with bacterial brain abscesses. With an MRI investigation of displacement and destruction of the brain tissue surrounding a glioblastoma
Front Oncol, 12, 846674
DOI 10.3389/fonc.2022.846674, PubMed 35965529
Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
J Transl Med, 20 (1), 225
DOI 10.1186/s12967-022-03432-5, PubMed 35568909
Correction to: Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
J Transl Med, 20 (1), 317
DOI 10.1186/s12967-022-03518-0, PubMed 35841045
Molecular pathological insights reveal a high number of unfavorable risk patients among children treated for medulloblastoma and CNS-PNET in Oslo 2005-2017
Pediatr Blood Cancer, 69 (9), e29736
DOI 10.1002/pbc.29736, PubMed 35570402
Anaplastic ganglioglioma-A diagnosis comprising several distinct tumour types
Neuropathol Appl Neurobiol, 48 (7), e12847
DOI 10.1111/nan.12847, PubMed 35977725
Publications 2021
Toward a better definition of focal cortical dysplasia: An iterative histopathological and genetic agreement trial
Epilepsia, 62 (6), 1416-1428
DOI 10.1111/epi.16899, PubMed 33949696
Intraoperative DNA methylation classification of brain tumors impacts neurosurgical strategy
Neurooncol Adv, 3 (1), vdab149
DOI 10.1093/noajnl/vdab149, PubMed 34729487
Analysis of autoantibody spectrum and human herpesvirus 6 in adult patients with 'early' versus 'late' diagnosis of 'possible limbic encephalitis'
Epilepsy Res, 176, 106698
DOI 10.1016/j.eplepsyres.2021.106698, PubMed 34246119
Neurosarcoidosis resembling multiple meningiomas: A misleading presentation of the disease and diagnostic challenge
Acta Radiol Open, 10 (7), 20584601211036550
DOI 10.1177/20584601211036550, PubMed 34377543
Publications 2020
Cut-off values for sufficient cortisol response to low dose Short Synacthen Test after surgery for non-functioning pituitary adenoma
Acta Neurochir (Wien), 162 (4), 845-852
DOI 10.1007/s00701-019-04068-z, PubMed 31907611
Same same but different: A Web-based deep learning application revealed classifying features for the histopathologic distinction of cortical malformations
Epilepsia, 61 (3), 421-432
DOI 10.1111/epi.16447, PubMed 32080846
Publications 2019
Longitudinal heterogeneity in glioblastoma: moving targets in recurrent versus primary tumors
J Transl Med, 17 (1), 96
DOI 10.1186/s12967-019-1846-y, PubMed 30894200
Publications 2018
The effect of human herpesvirus 6B infection on the MAPK pathway
Virus Res, 256, 134-141
DOI 10.1016/j.virusres.2018.08.014, PubMed 30130603
K27/G34 versus K28/G35 in histone H3-mutant gliomas: A note of caution
Acta Neuropathol, 136 (1), 175-176
DOI 10.1007/s00401-018-1867-2, PubMed 29766298
Pyrosequencing Analysis of MGMT Promoter Methylation in Meningioma
Cancer Genomics Proteomics, 15 (5), 379-385
DOI 10.21873/cgp.20096, PubMed 30194078
Publications 2017
Human Herpesvirus 6B Induces Hypomethylation on Chromosome 17p13.3, Correlating with Increased Gene Expression and Virus Integration
J Virol, 91 (11)
DOI 10.1128/JVI.02105-16, PubMed 28298607
Frontal cystic lesion with a contrast-enhancing mural nodule: Question
J. Clin. Neurosci., 37, 40
DOI 10.1016/j.jocn.2016.10.026
Frontal cystic lesion with a contrast-enhancing mural nodule: Answer
J. Clin. Neurosci., 37, 104
DOI 10.1016/j.jocn.2016.10.037
IDH-mutant giant cell glioblastoma: A neglected tumor variant?
Clin Neuropathol, 36 (6), 293-295
DOI 10.5414/NP301054, PubMed 29035191
Epilepsy-associated tumors in the context of the current 2016 WHO classification for tumors of the central nervous system
Z. Epileptol., 30 (3), 192-199
DOI 10.1007/s10309-017-0118-1
Large-scale analysis of herpesviridae in epilepsy-patients with signs of autoimmune encephalitis
Seizure, 53, 100-102
DOI 10.1016/j.seizure.2017.11.012, PubMed 29156319
Publications 2016
Differential expression of miR-184 in temporal lobe epilepsy patients with and without hippocampal sclerosis - Influence on microglial function
Sci Rep, 6, 33943
DOI 10.1038/srep33943, PubMed 27666871
Hippocampal internal architecture and postoperative seizure outcome in temporal lobe epilepsy due to hippocampal sclerosis
Seizure, 35, 65-71
DOI 10.1016/j.seizure.2016.01.007, PubMed 26803053
18F-fluoroethyl-L-tyrosine positron emission tomography-guided diagnosis of a malignant intramedullary spinal cord tumor
Oncol Lett, 12 (6), 4705-4707
DOI 10.3892/ol.2016.5234, PubMed 28105177
Non-paraneoplastic limbic encephalitis and central nervous HHV-6B reactivation: Causality or coincidence?
Neuropathology, 36 (4), 376-80
DOI 10.1111/neup.12283, PubMed 27431532
Neuropathological signs of inflammation correlate with mitochondrial DNA deletions in mesial temporal lobe epilepsy
Acta Neuropathol, 132 (2), 277-288
DOI 10.1007/s00401-016-1561-1, PubMed 26993140
Publications 2015
Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus
Nat Commun, 6, 6031
DOI 10.1038/ncomms7031, PubMed 25615886
Features of scalp EEG in unilateral mesial temporal lobe epilepsy due to hippocampal sclerosis: Determining factors and predictive value for epilepsy surgery
Clin Neurophysiol, 127 (2), 1081-1087
DOI 10.1016/j.clinph.2015.06.035, PubMed 26321666
Publications 2014
Large-scale analysis of viral nucleic acid spectrum in temporal lobe epilepsy biopsies
Epilepsia, 56 (2), 234-43
DOI 10.1111/epi.12890, PubMed 25530314
KPNA2 predicts long term survival in patients with anaplastic oligoastrocytomas
J Clin Neurosci, 21 (10), 1719-24
DOI 10.1016/j.jocn.2014.01.011, PubMed 24929863
Karyopherin a2 and chromosome region maintenance protein 1 expression in meningiomas: novel biomarkers for recurrence and malignant progression
J Neurooncol, 118 (2), 289-296
DOI 10.1007/s11060-014-1423-4, PubMed 24664371
In vivo mapping of hippocampal subfields in mesial temporal lobe epilepsy: relation to histopathology
Hum Brain Mapp, 35 (9), 4718-28
DOI 10.1002/hbm.22506, PubMed 24638919
Surgical resection can be successful in a large fraction of patients with drug-resistant epilepsy associated with multiple cerebral cavernous malformations
Neurosurgery, 74 (2), 147-53; discussion 153
DOI 10.1227/NEU.0000000000000210, PubMed 24435138
Publications 2013
Levetiracetam resistance: Synaptic signatures & corresponding promoter SNPs in epileptic hippocampi
Neurobiol Dis, 60, 115-25
DOI 10.1016/j.nbd.2013.08.015, PubMed 24018139
Focal cortical dysplasia type IIIc associates with multiple cerebral cavernomas
Epilepsy Res, 107 (1-2), 190-4
DOI 10.1016/j.eplepsyres.2013.07.006, PubMed 23968818
Vemurafenib for leptomeningeal melanomatosis
J Clin Oncol, 31 (11), e173-4
DOI 10.1200/JCO.2012.46.5773, PubMed 23460716
Surgical management and long-term seizure outcome after epilepsy surgery for different types of epilepsy associated with cerebral cavernous malformations
Epilepsia, 54 (9), 1699-706
DOI 10.1111/epi.12327, PubMed 23944932
Publications 2012
Intravascular CNS lymphoma: Successful therapy using high-dose methotrexate-based polychemotherapy
Exp Hematol Oncol, 1 (1), 37
DOI 10.1186/2162-3619-1-37, PubMed 23217063
Cliniconeuropathologic correlations show astroglial albumin storage as a common factor in epileptogenic vascular lesions
Epilepsia, 53 (3), 539-48
DOI 10.1111/j.1528-1167.2012.03405.x, PubMed 22372630
Albumin storage in neoplastic astroglial elements of gangliogliomas
Seizure, 22 (2), 144-50
DOI 10.1016/j.seizure.2012.10.014, PubMed 23182422
Publications 2011
Promoter variants determine γ-aminobutyric acid homeostasis-related gene transcription in human epileptic hippocampi
J Neuropathol Exp Neurol, 70 (12), 1080-8
DOI 10.1097/NEN.0b013e318238b9af, PubMed 22082659
Genetic analysis of tuberous-sclerosis genes 1 and 2 in nonlesional focal epilepsy
Epilepsy Behav, 21 (3), 233-7
DOI 10.1016/j.yebeh.2011.03.034, PubMed 21555252
Focal cortical dysplasia type IIb: completeness of cortical, not subcortical, resection is necessary for seizure freedom
Epilepsia, 52 (8), 1418-24
DOI 10.1111/j.1528-1167.2011.03158.x, PubMed 21740420
Publications 2010
Factors of influence upon overall survival in the treatment of intracranial MPNSTs. Review of the literature and report of a case
Radiat Oncol, 5, 114
DOI 10.1186/1748-717X-5-114, PubMed 21106096
Presence of human herpes virus 6 DNA exclusively in temporal lobe epilepsy brain tissue of patients with history of encephalitis
Epilepsia, 51 (12), 2478-83
DOI 10.1111/j.1528-1167.2010.02741.x, PubMed 21204811
Coincidence detection and stress modulation of spike time-dependent long-term depression in the hippocampus
J Neurosci, 30 (18), 6225-35
DOI 10.1523/JNEUROSCI.6411-09.2010, PubMed 20445048
Mitochondrial dysfunction due to Leber's hereditary optic neuropathy as a cause of visual loss during assessment for epilepsy surgery
Epilepsy Behav, 20 (1), 38-43
DOI 10.1016/j.yebeh.2010.11.008, PubMed 21145289
Publications 2009
Simple and complex dysembryoplastic neuroepithelial tumors (DNT) variants: clinical profile, MRI, and histopathology
Neuroradiology, 51 (7), 433-43
DOI 10.1007/s00234-009-0511-1, PubMed 19242688
Hamartin variants that are frequent in focal dysplasias and cortical tubers have reduced tuberin binding and aberrant subcellular distribution in vitro
J Neuropathol Exp Neurol, 68 (10), 1136-46
DOI 10.1097/NEN.0b013e3181b9a699, PubMed 19918125
Diagnostic value of N-methyl-D-aspartate receptor antibodies in women with new-onset epilepsy
Arch Neurol, 66 (4), 458-64
DOI 10.1001/archneurol.2009.5, PubMed 19364930
Increased frequency of distinct TSC2 allelic variants in focal cortical dysplasias with balloon cells and mineralization
Neuropathology, 29 (5), 559-65
DOI 10.1111/j.1440-1789.2009.01018.x, PubMed 19422538
Publications 2008
Array analysis of epilepsy-associated gangliogliomas reveals expression patterns related to aberrant development of neuronal precursors
Brain, 131 (Pt 11), 3034-50
DOI 10.1093/brain/awn233, PubMed 18819986