Runar Almaas
- Scientist and group leader, Head of Department; MD, PhD
- +47 23 07 24 94
Publications 2024
Parenteral nutrition emulsion inhibits CYP3A4 in an iPSC derived liver organoids testing platform
J Pediatr Gastroenterol Nutr, 78 (5), 1047-1058
DOI 10.1002/jpn3.12195, PubMed 38529852
Effect of hypoxia on aquaporins and hepatobiliary transport systems in human hepatic cells
Pediatr Res (in press)
DOI 10.1038/s41390-024-03368-0, PubMed 38951656
Differences in bile acid profiles between cholestatic diseases - Development of a high throughput assay for dried bloodspots
Clin Chim Acta, 562, 119864
DOI 10.1016/j.cca.2024.119864, PubMed 38992821
Corrigendum to "Differences in bile acid profiles between cholestatic diseases - Development of a high throughput assay for dried bloodspots" [Clin. Chim. Acta 562 (2024) 119864]
Clin Chim Acta, 562, 119882
DOI 10.1016/j.cca.2024.119882, PubMed 39054215
Publications 2023
Aagenaes syndrome/lymphedema cholestasis syndrome 1 is caused by a founder variant in the 5'-untranslated region of UNC45A
J Hepatol, 79 (4), 945-954
DOI 10.1016/j.jhep.2023.05.037, PubMed 37328071
Scalable production of tissue-like vascularized liver organoids from human PSCs
Exp Mol Med, 55 (9), 2005-2024
DOI 10.1038/s12276-023-01074-1, PubMed 37653039
A loss-of-function mutation in human Oxidation Resistance 1 disrupts the spatial-temporal regulation of histone arginine methylation in neurodevelopment
Genome Biol, 24 (1), 216
DOI 10.1186/s13059-023-03037-1, PubMed 37773136
Hunting for the elusive target antigen in gestational alloimmune liver disease (GALD)
PLoS One, 18 (10), e0286432
DOI 10.1371/journal.pone.0286432, PubMed 37862305
Publications 2022
50 Years Ago in TheJournalofPediatrics: Hemiallogeneic Stem Cell Transplantation-from Last Resort to a Viable Treatment Option
J Pediatr, 243, 213
DOI 10.1016/j.jpeds.2021.12.064, PubMed 35341548
Mycophenolate mofetil use is associated with reduced incidence of food allergy in liver transplanted children
J Pediatr Gastroenterol Nutr, 75 (1), 138-144
DOI 10.1097/MPG.0000000000003509, PubMed 35666879
Publications 2021
50 Years Ago in TheJournalofPediatrics: Hepatopulmonary Syndrome: Transplantation Is the Big Difference
J Pediatr, 229, 69
DOI 10.1016/j.jpeds.2020.08.074, PubMed 33487230
50 Years Ago in TheJournalofPediatrics: Pregnancy in Women with Galactosemia
J Pediatr, 233, 118
DOI 10.1016/j.jpeds.2021.02.032, PubMed 34030831
50 Years Ago in TheJournalofPediatrics: Diagnosis of Self-Mutilation and Hyperuricemia
J Pediatr, 237, 86
DOI 10.1016/j.jpeds.2021.07.034, PubMed 34563325
Hepatopulmonary Syndrome: Transplantation Is the Big Difference
J. Pediatr., 229, 69
Pregnancy in Women with Galactosemia
J. Pediatr., 233, 118
Diagnosis of Self-Mutilation and Hyperuricemia
J. Pediatr., 237, 86
Spectrum of Fontan-associated liver disease assessed by MRI and US in young adolescents
Abdom Radiol (NY), 46 (7), 3205-3216
DOI 10.1007/s00261-021-02994-0, PubMed 33688987
Impaired Neurocognitive Performance in Children after Liver Transplantation
J Pediatr, 243, 135-141.e2
DOI 10.1016/j.jpeds.2021.12.033, PubMed 34953814
Publications 2020
MicroRNA in dried blood spots from patients with Aagenaes syndrome and evaluation of pre-analytical and analytical factors
Pediatr Res, 89 (7), 1780-1787
DOI 10.1038/s41390-020-01153-3, PubMed 32932426
Partial Biliary Diversion May Promote Long-Term Relief of Pruritus and Native Liver Survival in Children with Cholestatic Liver Diseases
Eur J Pediatr Surg, 31 (4), 341-346
DOI 10.1055/s-0040-1714657, PubMed 32707578
Hepatic magnetic resonance T1-mapping and extracellular volume fraction compared to shear-wave elastography in pediatric Fontan-associated liver disease
Pediatr Radiol, 51 (1), 66-76
DOI 10.1007/s00247-020-04805-y, PubMed 33033916
Cytokine profile in children with food allergy following liver transplantation
Pediatr Transplant, 24 (2), e13657
DOI 10.1111/petr.13657, PubMed 32067305
GDF-15 - A matter of the heart or the kidney?
Int J Cardiol, 313, 47
DOI 10.1016/j.ijcard.2020.03.017, PubMed 32517965
Growth Differentiation Factor 15 in Children with Chronic Kidney Disease and after Renal Transplantation
Dis Markers, 2020, 6162892
DOI 10.1155/2020/6162892, PubMed 32089755
Publications 2019
Diagnosing autoimmune hepatitis in paediatric patients - we still haven't found what we are looking for
Acta Paediatr, 108 (9), 1562-1563
DOI 10.1111/apa.14890, PubMed 31264728
Progressive loss of bone mass in children with Fontan circulation
Congenit Heart Dis, 14 (6), 996-1004
DOI 10.1111/chd.12848, PubMed 31600039
Measured GFR by Utilizing Population Pharmacokinetic Methods to Determine Iohexol Clearance
Kidney Int Rep, 5 (2), 189-198
DOI 10.1016/j.ekir.2019.11.012, PubMed 32043033
Publications 2018
Asthma, Eczema, and Food Allergy in Children Following Liver Transplantation
J Pediatr, 204, 263-269
DOI 10.1016/j.jpeds.2018.08.050, PubMed 30270158
Outcome for biliary atresia patients treated at a low-volume centre
Scand J Gastroenterol, 53 (4), 471-474
DOI 10.1080/00365521.2018.1439097, PubMed 29546790
Publications 2017
Outcomes of biliary atresia in the Nordic countries - a multicenter study of 158 patients during 2005-2016
J Pediatr Surg, 53 (8), 1509-1515
DOI 10.1016/j.jpedsurg.2017.08.048, PubMed 28947328
No effect of treatment with intravenous ganciclovir on Epstein-Barr virus viremia demonstrated after pediatric liver transplantation
Pediatr Transplant, 21 (6)
DOI 10.1111/petr.13010, PubMed 28653462
Publications 2016
Small-Molecule-Directed Hepatocyte-Like Cell Differentiation of Human Pluripotent Stem Cells
Curr Protoc Stem Cell Biol, 38, 1G.6.1-1G.6.18
DOI 10.1002/cpsc.13, PubMed 27532814
Publications 2015
Impaired motor competence in children with transplanted liver
J Pediatr Gastroenterol Nutr, 60 (6), 723-8
DOI 10.1097/MPG.0000000000000757, PubMed 25658058
Publications 2013
Clinical experience with microdialysis catheters in pediatric liver transplants
Liver Transpl, 19 (3), 305-14
DOI 10.1002/lt.23578, PubMed 23193034
High dietary folic Acid and high plasma folate in children and adults with phenylketonuria
JIMD Rep, 13, 83-90
DOI 10.1007/8904_2013_260, PubMed 24136656
Effect of operator experience and frequency of procedure performance on complication rate after ultrasound-guided percutaneous liver biopsies
J Pediatr Gastroenterol Nutr, 57 (5), 638-43
DOI 10.1097/MPG.0b013e3182a0c7a5, PubMed 24177785
Publications 2012
Dexamethasone reduces bilirubin-induced toxicity and IL-8 and MCP-1 release in human NT2-N neurons
Brain Res, 1458, 12-7
DOI 10.1016/j.brainres.2012.04.007, PubMed 22546346
Inflammatory markers sampled by microdialysis catheters distinguish rejection from ischemia in liver grafts
Liver Transpl, 18 (12), 1421-9
DOI 10.1002/lt.23503, PubMed 22767413
Early bedside detection of ischemia and rejection in liver transplants by microdialysis
Liver Transpl, 18 (7), 839-49
DOI 10.1002/lt.23425, PubMed 22407878
Evaluation of risk factors for bleeding after liver biopsy in children
J Pediatr Gastroenterol Nutr, 55 (1), 82-7
DOI 10.1097/MPG.0b013e318249c12a, PubMed 22249806
Publications 2006
Effect of acidosis on IL-8 and MCP-1 during hypoxia and reoxygenation in human NT2-N neurons
Brain Res, 1113 (1), 64-73
DOI 10.1016/j.brainres.2006.07.051, PubMed 16919250
Recovery after short-term bilirubin exposure in human NT2-N neurons
Brain Res, 1103 (1), 56-64
DOI 10.1016/j.brainres.2006.05.083, PubMed 16814266
Publications 2005
Acidosis during reoxygenation has an early detrimental effect on neuronal metabolic activity
Pediatr Res, 57 (4), 488-93
DOI 10.1203/01.PDR.0000155946.82230.2E, PubMed 15695602
Management of suspected pulmonary embolism (PE) by D-dimer and multi-slice computed tomography in outpatients: an outcome study
J Thromb Haemost, 3 (9), 1926-32
DOI 10.1111/j.1538-7836.2005.01544.x, PubMed 16102097
Synergistic protection of a general caspase inhibitor and MK-801 in bilirubin-induced cell death in human NT2-N neurons
Pediatr Res, 59 (1), 72-7
DOI 10.1203/01.pdr.0000191135.63586.08, PubMed 16326984
Publications 2004
Bilirubin induces apoptosis and necrosis in human NT2-N neurons
Pediatr Res, 57 (2), 179-84
DOI 10.1203/01.PDR.0000148711.11519.A5, PubMed 15611354
Publications 2003
Hypoxia in human NT2-N neurons: the role of free radicals and glutamate
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 124, 1 b. (flere pag.)
BIBSYS 031759297, ISBN 82-8072-092-8
Acidosis has opposite effects on neuronal survival during hypoxia and reoxygenation
J Neurochem, 84 (5), 1018-27
DOI 10.1046/j.1471-4159.2003.01593.x, PubMed 12603826
Publications 2002
Neuronal formation of free radicals plays a minor role in hypoxic cell death in human NT2-N neurons
Pediatr Res, 51 (2), 136-43
DOI 10.1203/00006450-200202000-00004, PubMed 11809906
Publications 2000
Reversal of meconium inhibition of pulmonary surfactant by ferric chloride, copper chloride, and acetic acid
Am J Respir Crit Care Med, 162 (5), 1789-94
DOI 10.1164/ajrccm.162.5.2002068, PubMed 11069814
Effect of barbiturates on hydroxyl radicals, lipid peroxidation, and hypoxic cell death in human NT2-N neurons
Anesthesiology, 92 (3), 764-74
DOI 10.1097/00000542-200003000-00020, PubMed 10719955
Publications 1998
Diving seals, ischemia-reperfusion and oxygen radicals
Comp Biochem Physiol A Mol Integr Physiol, 119 (4), 975-80
DOI 10.1016/s1095-6433(98)00012-9, PubMed 9773490
Acute effects on systemic circulation after intratracheal instillation of Curosurf or Survanta in surfactant-depleted newborn piglets
Acta Paediatr, 87 (3), 297-303
DOI 10.1080/08035259850157354, PubMed 9560037
Hypoxic cell death in human NT2-N neurons: involvement of NMDA and non-NMDA glutamate receptors
J Neurochem, 71 (4), 1544-53
DOI 10.1046/j.1471-4159.1998.71041544.x, PubMed 9751188
Publications 1997
Ascorbic acid enhances hydroxyl radical formation in iron-fortified infant cereals and infant formulas
Eur J Pediatr, 156 (6), 488-92
DOI 10.1007/s004310050645, PubMed 9208249
Plasma hypoxanthine reacts more abruptly to changes in oxygenation than base deficit and uric acid in newborn piglets
J Perinat Med, 25 (4), 353-60
DOI 10.1515/jpme.1997.25.4.353, PubMed 9350606
Explaining change in the international agro-food system
Rev. Int. Polit. Econ., 4 (4), 611-629
DOI 10.1080/09672299708565785
Publications 1995
Effect of sciatic nerve section on neural ingrowth into the rat tibial fracture callus
Clin Orthop Relat Res (311), 247-57
PubMed 7634582
Release of xanthine oxidase to the systemic circulation during resuscitation from severe hypoxemia in newborn pigs
Acta Paediatr, 84 (5), 507-11
DOI 10.1111/j.1651-2227.1995.tb13683.x, PubMed 7633144
Publications 1994
THE RISE AND FALL OF AGRICULTURAL POLICY CYCLES - FROM PLANNED-ECONOMY TO GREEN LIBERALISM
J. Rural Stud., 10 (1), 15-25
DOI 10.1016/0743-0167(94)90003-5
The neuronal regulation of fracture healing. Effects of sciatic nerve resection in rat tibia
Acta Orthop Scand, 65 (3), 299-304
DOI 10.3109/17453679408995457, PubMed 8042482
Changes in apnea and autoresuscitation in piglets after intravenous and intrathecal interleukin-1 beta injection
J Perinat Med, 22 (5), 421-32
DOI 10.1515/jpme.1994.22.5.421, PubMed 7791018