Gunhild Trøen
- Engineer; PhD
Publications 2024
Multi-omics profiling of longitudinal samples reveals early genomic changes in follicular lymphoma
Blood Cancer J, 14 (1), 147
DOI 10.1038/s41408-024-01124-5, PubMed 39191762
Molecular genetic characterization of myeloid neoplasms with idic(X)(q13) and i(X)(q10)
Front Oncol, 14, 1428984
DOI 10.3389/fonc.2024.1428984, PubMed 39391249
Gene expression analysis revealed downregulation of complement receptor 1 in clonal B cells in cold agglutinin disease
Clin Exp Immunol, 216 (1), 45-54
DOI 10.1093/cei/uxad135, PubMed 38133636
Correction: Whole exome sequencing of high-risk neuroblastoma identifies novel non-synonymous variants
PLoS One, 19 (7), e0306687
DOI 10.1371/journal.pone.0306687, PubMed 38950054
Publications 2022
Integrating whole genome sequencing, methylation, gene expression, topological associated domain information in regulatory mutation prediction: A study of follicular lymphoma
Comput Struct Biotechnol J, 20, 1726-1742
DOI 10.1016/j.csbj.2022.03.023, PubMed 35495111
Whole exome sequencing of high-risk neuroblastoma identifies novel non-synonymous variants
PLoS One, 17 (8), e0273280
DOI 10.1371/journal.pone.0273280, PubMed 36037157
Publications 2021
The mutational landscape of cold agglutinin disease: CARD11 and CXCR4 mutations are correlated with lower hemoglobin levels
Am J Hematol, 96 (8), E279-E283
DOI 10.1002/ajh.26205, PubMed 33891703
Publications 2020
Cold agglutinin-associated B-cell lymphoproliferative disease shows highly recurrent gains of chromosome 3 and 12 or 18
Blood Adv, 4 (6), 993-996
DOI 10.1182/bloodadvances.2020001608, PubMed 32168377
11q Deletion or ALK Activity Curbs DLG2 Expression to Maintain an Undifferentiated State in Neuroblastoma
Cell Rep, 32 (12), 108171
DOI 10.1016/j.celrep.2020.108171, PubMed 32966799
Mutational dynamics and immune evasion in diffuse large B-cell lymphoma explored in a relapse-enriched patient series
Blood Adv, 4 (9), 1859-1866
DOI 10.1182/bloodadvances.2019001325, PubMed 32374878
Publications 2019
MX 2 is a novel regulator of cell cycle in melanoma cells
Pigment Cell Melanoma Res, 33 (3), 446-457
DOI 10.1111/pcmr.12837, PubMed 31660681
Publications 2018
The MCL35 gene expression proliferation assay predicts high-risk MCL patients in a Norwegian cohort of younger patients given intensive first line therapy
Br J Haematol, 183 (2), 225-234
DOI 10.1111/bjh.15518, PubMed 30080252
Publications 2017
Frequent somatic mutations of KMT2D (MLL2) and CARD11 genes in primary cold agglutinin disease
Br J Haematol, 183 (5), 838-842
DOI 10.1111/bjh.15063, PubMed 29265349
Folliculotropic Mycosis Fungoides with Skewed T-cell Receptor CDR3 Motif: Suggestive of Lipid-antigen Selection?
Acta Derm Venereol, 97 (9), 1081-1086
DOI 10.2340/00015555-2722, PubMed 28597017
Publications 2016
Immunoglobulin heavy and light chain gene features are correlated with primary cold agglutinin disease onset and activity
Haematologica, 101 (9), e361-4
DOI 10.3324/haematol.2016.146126, PubMed 27198717
Distinct patterns of B-cell receptor signaling in non-Hodgkin lymphomas identified by single-cell profiling
Blood, 129 (6), 759-770
DOI 10.1182/blood-2016-05-718494, PubMed 28011673
Publications 2015
Lymphoplasmacytic lymphoma and marginal zone lymphoma in the bone marrow: paratrabecular involvement as an important distinguishing feature
Am J Clin Pathol, 143 (6), 797-806
DOI 10.1309/AJCP6ZODWV1CIDME, PubMed 25972321
Primary diffuse large B-cell lymphoma associated with clonally-related monoclonal B lymphocytosis indicates a common precursor cell
Haematologica, 100 (10), e415-8
DOI 10.3324/haematol.2015.126656, PubMed 26001788
Comprehensive genome-wide transcription factor analysis reveals that a combination of high affinity and low affinity DNA binding is needed for human gene regulation
BMC Genomics, 16 Suppl 7 (Suppl 7), S12
DOI 10.1186/1471-2164-16-S7-S12, PubMed 26099425
Publications 2014
A gene panel, including LRP12, is frequently hypermethylated in major types of B-cell lymphoma
PLoS One, 9 (9), e104249
DOI 10.1371/journal.pone.0104249, PubMed 25226156
Multiple distinct T-cell clones in folliculotropic mycosis fungoides
Am J Dermatopathol, 36 (12), 972-6
DOI 10.1097/DAD.0000000000000095, PubMed 25140661
Publications 2013
Identification of highly methylated genes across various types of B-cell non-hodgkin lymphoma
PLoS One, 8 (11), e79602
DOI 10.1371/journal.pone.0079602, PubMed 24260260
Colorectal cancer DNA methylation marker panel validated with high performance in Non-Hodgkin lymphoma
Epigenetics, 9 (3), 428-36
DOI 10.4161/epi.27554, PubMed 24362313
Whole-genome integrative analysis reveals expression signatures predicting transformation in follicular lymphoma
Blood, 123 (7), 1051-4
DOI 10.1182/blood-2013-07-512392, PubMed 24357726
Primary cold agglutinin-associated lymphoproliferative disease: a B-cell lymphoma of the bone marrow distinct from lymphoplasmacytic lymphoma
Haematologica, 99 (3), 497-504
DOI 10.3324/haematol.2013.091702, PubMed 24143001
CD79B and MYD88 Mutations in Splenic Marginal Zone Lymphoma
ISRN Oncol, 2013, 252318
DOI 10.1155/2013/252318, PubMed 23378931
Publications 2012
Monocytoid B cells: an enigmatic B cell subset showing evidence of extrafollicular immunoglobulin gene somatic hypermutation
Scand J Immunol, 75 (5), 500-9
DOI 10.1111/j.1365-3083.2012.02688.x, PubMed 22486786
Publications 2011
Identification of the TAF15-ZNF384 fusion gene in two new cases of acute lymphoblastic leukemia with a t(12;17)(p13;q12)
Cancer Genet, 204 (3), 147-52
DOI 10.1016/j.cancergen.2011.01.003, PubMed 21504714
Splenic marginal zone lymphoma with VH1-02 gene rearrangement expresses poly- and self-reactive antibodies with similar reactivity
Blood, 118 (12), 3331-9
DOI 10.1182/blood-2011-03-341651, PubMed 21725051
Publications 2010
Genomic alterations reveal potential for higher grade transformation in follicular lymphoma and confirm parallel evolution of tumor cell clones
Blood, 116 (9), 1489-97
DOI 10.1182/blood-2010-03-272278, PubMed 20505157
Publications 2009
Transformation of B cell lymphoma to histiocytic sarcoma: somatic mutations of PAX-5 gene with loss of expression cannot explain transdifferentiation
J Hematop, 2 (3), 135-41
DOI 10.1007/s12308-009-0031-2, PubMed 19669194
[Molecular diagnosis of malignant lymphomas]
Tidsskr Nor Laegeforen, 129 (22), 2352-6
DOI 10.4045/tidsskr.09.0704, PubMed 19935935
Publications 2008
Stromal gene signatures in large-B-cell lymphomas
N Engl J Med, 359 (22), 2313-23
DOI 10.1056/NEJMoa0802885, PubMed 19038878
The fatty acid binding protein 7 (FABP7) is involved in proliferation and invasion of melanoma cells
BMC Cancer, 8, 276
DOI 10.1186/1471-2407-8-276, PubMed 18826602
NOTCH2 mutations in marginal zone lymphoma
Haematologica, 93 (7), 1107-9
DOI 10.3324/haematol.11635, PubMed 18508802
The clinicopathological and prognostic impact of 14-3-3 sigma expression on vulvar squamous cell carcinomas
BMC Cancer, 8, 308
DOI 10.1186/1471-2407-8-308, PubMed 18950492
Publications 2006
Peripheral T-cell lymphoma with involvement of the expanded mantle zone
Virchows Arch, 449 (1), 78-87
DOI 10.1007/s00428-005-0123-z, PubMed 16633785
The expression of fibroblast growth factors and their receptors in Hodgkin's lymphoma
J Pathol, 208 (3), 431-8
DOI 10.1002/path.1900, PubMed 16353171
Publications 2005
Molecular cloning and characterization of STAMP2, an androgen-regulated six transmembrane protein that is overexpressed in prostate cancer
Oncogene, 24 (31), 4934-45
DOI 10.1038/sj.onc.1208677, PubMed 15897894
Publications 2004
Constitutive expression of the AP-1 transcription factors c-jun, junD, junB, and c-fos and the marginal zone B-cell transcription factor Notch2 in splenic marginal zone lymphoma
J Mol Diagn, 6 (4), 297-307
DOI 10.1016/S1525-1578(10)60525-9, PubMed 15507668
Prognostic significance of dysadherin expression in cervical squamous cell carcinoma
Pathol Oncol Res, 10 (4), 212-8
DOI 10.1007/BF03033763, PubMed 15619642
Prognostic value of EphA2 and EphrinA-1 in squamous cell cervical carcinoma
Gynecol Oncol, 94 (2), 312-9
DOI 10.1016/j.ygyno.2004.05.019, PubMed 15297167
Publications 2000
Characterization of PSKH1, a novel human protein serine kinase with centrosomal, golgi, and nuclear localization
Genomics, 70 (1), 82-92
DOI 10.1006/geno.2000.6365, PubMed 11087665
Evidence for independent control at the mRNA and protein levels of cellular retinol binding protein 1 in rat Sertoli cells
J Reprod Fertil, 119 (1), 101-9
DOI 10.1530/jrf.0.1190101, PubMed 10864819
Publications 1999
Vitamin A-sensitive tissues in transgenic mice expressing high levels of human cellular retinol-binding protein type I are not altered phenotypically
J Nutr, 129 (9), 1621-7
DOI 10.1093/jn/129.9.1621, PubMed 10460195
Publications 1997
Retinyl ester storage is altered in liver stellate cells and in HL60 cells transfected with cellular retinol-binding protein type I
Int J Biochem Cell Biol, 29 (2), 381-9
DOI 10.1016/s1357-2725(96)00068-4, PubMed 9147140
Publications 1996
Retinyl ester storage is normal in transgenic mice with enhanced expression of cellular retinol-binding protein type I
J Nutr, 126 (11), 2709-19
DOI 10.1093/jn/126.11.2709, PubMed 8914940
Function of cellular retinol-binding protein I in metabolism of retinol
Institute for Nutrition Research and Department of Biochemistry, University of Oslo, [Oslo], 1 b. (flere pag.)
BIBSYS 961594594, ISBN 82-992777-9-5
Publications 1994
Characterization of liver stellate cell retinyl ester storage
Biochem J, 300 ( Pt 3) (Pt 3), 793-8
DOI 10.1042/bj3000793, PubMed 8010962
Publications 1993
The effect of retinoids and clofibric acid on the peroxisomal oxidation of palmitic acid and of 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestanoic acid in rat and rabbit hepatocytes
Biochim Biophys Acta, 1168 (1), 100-7
DOI 10.1016/0005-2760(93)90272-b, PubMed 8504135
Publications 1991
RETINOL ESTERIFICATION IN RABBIT LIVER STELLATE CELLS
CELLS OF THE HEPATIC SINUSOID, VOL 3, 266-268