Sverre-Henning Brorson

  • Senior scientist; PhD
  • +47 23 07 14 35
 

Publications 2021

Frerker N, Karlsen TA, Lilledahl MB, Brorson SH, Tibballs JE, Brinchmann JE (2021)
Scaffold-Free Engineering of Human Cartilage Implants
Cartilage, 13 (1_suppl), 1237S-1249S
DOI 10.1177/19476035211007923, PubMed 33858229

Publications 2020

Caglayan S, Hashim A, Cieslar-Pobuda A, Jensen V, Behringer S, Talug B, Chu DT, Pecquet C, Rogne M, Brech A, Brorson SH, Nagelhus EA, Hannibal L, Boschi A, Taskén K, Staerk J (2020)
Optic Atrophy 1 Controls Human Neuronal Development by Preventing Aberrant Nuclear DNA Methylation
iScience, 23 (6), 101154
DOI 10.1016/j.isci.2020.101154, PubMed 32450518

Publications 2017

Acevedo R, Zayas C, Norheim G, Fernández S, Cedré B, Aranguren Y, Cuello M, Rodriguez Y, González H, Mandiarote A, Pérez M, Hernández M, Hernández-Cedeño M, González D, Brorson SH, Rosenqvist E, Naess L, Tunheim G, Cardoso D, García L (2017)
Outer membrane vesicles extracted from Neisseria meningitidis serogroup X for prevention of meningococcal disease in Africa
Pharmacol Res, 121, 194-201
DOI 10.1016/j.phrs.2017.04.030, PubMed 28495657

Olsen MB, Hildrestrand GA, Scheffler K, Vinge LE, Alfsnes K, Palibrk V, Wang J, Neurauter CG, Luna L, Johansen J, Øgaard JDS, Ohm IK, Slupphaug G, Kuśnierczyk A, Fiane AE, Brorson SH, Zhang L, Gullestad L, Louch WE, Iversen PO, Østlie I, Klungland A, Christensen G, Sjaastad I, Sætrom P et al. (2017)
NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture
Cell Rep, 18 (1), 82-92
DOI 10.1016/j.celrep.2016.12.009, PubMed 28052262

Publications 2015

Herum KM, Lunde IG, Skrbic B, Louch WE, Hasic A, Boye S, Unger A, Brorson SH, Sjaastad I, Tønnessen T, Linke WA, Gomez MF, Christensen G (2015)
Syndecan-4 is a key determinant of collagen cross-linking and passive myocardial stiffness in the pressure-overloaded heart
Cardiovasc Res, 106 (2), 217-26
DOI 10.1093/cvr/cvv002, PubMed 25587045

Publications 2014

Solberg LB, Brorson SH, Stordalen GA, Bækkevold ES, Andersson G, Reinholt FP (2014)
Increased tartrate-resistant Acid phosphatase expression in osteoblasts and osteocytes in experimental osteoporosis in rats
Calcif Tissue Int, 94 (5), 510-21
DOI 10.1007/s00223-013-9834-3, PubMed 24395179

Solberg LB, Stang E, Brorson SH, Andersson G, Reinholt FP (2014)
Tartrate-resistant acid phosphatase (TRAP) co-localizes with receptor activator of NF-KB ligand (RANKL) and osteoprotegerin (OPG) in lysosomal-associated membrane protein 1 (LAMP1)-positive vesicles in rat osteoblasts and osteocytes
Histochem Cell Biol, 143 (2), 195-207
DOI 10.1007/s00418-014-1272-4, PubMed 25201349

Publications 2013

Hessle L, Stordalen GA, Wenglén C, Petzold C, Tanner E, Brorson SH, Baekkevold ES, Önnerfjord P, Reinholt FP, Heinegård D (2013)
The skeletal phenotype of chondroadherin deficient mice
PLoS One, 8 (6), e63080
DOI 10.1371/journal.pone.0063080, PubMed 23755099

Publications 2012

Kumar NT, Liestøl K, Løberg EM, Reims HM, Brorson SH, Maehlen J (2012)
The apolipoprotein E polymorphism and cardiovascular diseases--an autopsy study
Cardiovasc Pathol, 21 (6), 461-9
DOI 10.1016/j.carpath.2012.02.005, PubMed 22440829

Paulsen G, Egner I, Raastad T, Reinholt F, Owe S, Lauritzen F, Brorson SH, Koskinen S (2012)
Inflammatory markers CD11b, CD16, CD66b, CD68, myeloperoxidase and neutrophil elastase in eccentric exercised human skeletal muscles
Histochem Cell Biol, 139 (5), 691-715
DOI 10.1007/s00418-012-1061-x, PubMed 23224298

Publications 2010

Melhus G, Brorson SH, Baekkevold ES, Andersson G, Jemtland R, Olstad OK, Reinholt FP (2010)
Gene expression and distribution of key bone turnover markers in the callus of estrogen-deficient, vitamin D-depleted rats
Calcif Tissue Int, 87 (1), 77-89
DOI 10.1007/s00223-010-9371-2, PubMed 20495792

Publications 2009

Brorson Ø, Brorson SH, Scythes J, MacAllister J, Wier A, Margulis L (2009)
Destruction of spirochete Borrelia burgdorferi round-body propagules (RBs) by the antibiotic tigecycline
Proc Natl Acad Sci U S A, 106 (44), 18656-61
DOI 10.1073/pnas.0908236106, PubMed 19843691

Publications 2008

Pedersen ME, Fortunati D, Nielsen M, Brorson SH, Lekva T, Nissen-Meyer LS, Gautvik VT, Shahdadfar A, Gautvik KM, Jemtland R (2008)
Calmodulin-dependent kinase 1beta is expressed in the epiphyseal growth plate and regulates proliferation of mouse calvarial osteoblasts in vitro
Bone, 43 (4), 700-7
DOI 10.1016/j.bone.2008.06.006, PubMed 18620088

Publications 2007

Brorson O, Brorson SH (2007)
Grapefruit seed extract is a powerful in vitro agent against motile and cystic forms of Borrelia burgdorferi sensu lato
Infection, 35 (3), 206-8
DOI 10.1007/s15010-007-6105-0, PubMed 17565468

Publications 2006

Brorson SH, Reinholt FP (2006)
The intensity of immunogold labeling of deplasticized acrylic sections compared to deplasticized epoxy sections-Theoretical deductions and experimental data
Micron, 39 (2), 144-50
DOI 10.1016/j.micron.2006.11.006, PubMed 17188881

Brorson Ø, Brorson SH (2006)
An in vitro study of the activity of telithromycin against mobile and cystic forms of Borrelia afzelii
Infection, 34 (1), 26-8
DOI 10.1007/s15010-006-4121-0, PubMed 16501899

Publications 2005

Solberg LB, Melhus G, Brorson SH, Wendel M, Reinholt FP (2005)
Heat-induced retrieval of immunogold labeling for nucleobindin and osteoadherin from Lowicryl sections of bone
Micron, 37 (4), 347-54
DOI 10.1016/j.micron.2005.11.010, PubMed 16387503

Publications 2004

Brorson O, Brorson SH (2004)
An in vitro study of the susceptibility of mobile and cystic forms of Borrelia burgdorferi to tinidazole
Int Microbiol, 7 (2), 139-42
PubMed 15248163

Brorson SH (2004)
A method for measurements of the efficiency of immunogold labelling of epoxy-embedded proteins subjected to different retrieval techniques
Micron, 35 (7), 619-21
DOI 10.1016/j.micron.2004.02.001, PubMed 15219909

Went P, Ascani S, Strøm E, Brorson SH, Musso M, Zinzani PL, Falini B, Dirnhofer S, Pileri S (2004)
Nodal marginal-zone lymphoma associated with monoclonal light-chain and heavy-chain deposition disease
Lancet Oncol, 5 (6), 381-3
DOI 10.1016/S1470-2045(04)01495-0, PubMed 15172359

Publications 2003

Otto M, Hansen T, Bertz S, Strøm EH, Brorson SH, Mihatsch MJ, Kriegsmann J (2003)
[Lupus nephritis with crystal structures in glomerulopathy ]
Pathologe, 24 (6), 433-8
DOI 10.1007/s00292-003-0658-1, PubMed 14605847

Publications 2002

Brorson O, Brorson SH (2002)
An in vitro study of the susceptibility of mobile and cystic forms of Borrelia burgdorferi to hydroxychloroquine
Int Microbiol, 5 (1), 25-31
DOI 10.1007/s10123-002-0055-2, PubMed 12102233

Brorson SH (2002)
pH-dependent effect of heat-induced antigen retrieval of epoxy section for electron microscopy
Micron, 33 (5), 481-2
DOI 10.1016/s0968-4328(01)00040-3, PubMed 11976035

Kumar T, Liestøl K, Maehlen J, Hiorth A, Jettestuen E, Lind H, Brorson SH (2002)
Allele frequencies of apolipoprotein E gene polymorphisms in the protein coding region and promoter region (-491A/T) in a healthy Norwegian population
Hum Biol, 74 (1), 137-42
DOI 10.1353/hub.2002.0006, PubMed 11931575

Lund PK, Namork E, Brorson SH, Westvik AB, Joø GB, Øvstebø R, Kierulf P (2002)
The fate of monocytes during 24 h of culture as revealed by flow cytometry and electron microscopy
J Immunol Methods, 270 (1), 63-76
DOI 10.1016/s0022-1759(02)00272-7, PubMed 12379339

Aarset H, Dekker J, Brorson SH, Husby G (2002)
Crystal-induced arthritis mimicking rheumatoid arthritis in a patient with monoclonal gammopathy
Arthritis Rheum, 46 (10), 2816
DOI 10.1002/art.10553, PubMed 12384945

Publications 2001

Brorson O, Brorson SH (2001)
Susceptibility of motile and cystic forms of Borrelia burgdorferi to ranitidine bismuth citrate
Int Microbiol, 4 (4), 209-15
DOI 10.1007/s10123-001-0039-7, PubMed 12051564

Brorson O, Brorson SH, Henriksen TH, Skogen PR, Schøyen R (2001)
Association between multiple sclerosis and cystic structures in cerebrospinal fluid
Infection, 29 (6), 315-9
DOI 10.1007/s15010-001-9144-y, PubMed 11787831

Brorson SH (2001)
Deplasticizing or etching of epoxy sections with different concentrations of sodium ethoxide to enhance the immunogold labeling
Micron, 32 (2), 101-5
DOI 10.1016/s0968-4328(00)00006-8, PubMed 10936453

Brorson SH (2001)
Heat-induced antigen retrieval of epoxy sections for electron microscopy
Histol Histopathol, 16 (3), 923-30
DOI 10.14670/HH-16.923, PubMed 11510983

Brorson SH, Hansen AR, Nielsen HZ, Woxen IK (2001)
A comparative study of the immunogold labeling on H(2)O(2)-treated and heated epoxy sections
Micron, 32 (2), 147-51
DOI 10.1016/s0968-4328(99)00107-9, PubMed 10936458

Brorson SH, Nguyen GH (2001)
Increased level of immunogold labeling of epoxy sections by rising the temperature significantly beyond 100 degrees C in the antigen retrieval medium
Micron, 32 (6), 591-7
DOI 10.1016/s0968-4328(00)00052-4, PubMed 11166579

Wessel N, Liestøl K, Maehlen J, Brorson SH (2001)
The apolipoprotein E epsilon4 allele is no risk factor for prostate cancer in the Norwegian population
Br J Cancer, 85 (9), 1418
DOI 10.1054/bjoc.2001.2098, PubMed 11720484

Publications 2000

Liestøl K, Kvittingen EA, Rootwelt H, Dunlop O, Goplen AK, Pedersen JC, Brorson SH, Børresen-Dale AL, Myrvang B, Maehlen J (2000)
Association between apolipoprotein E genotypes and cancer risk in patients with acquired immunodeficiency syndrome
Cancer Detect Prev, 24 (5), 496-9
PubMed 11129992

Publications 1999

Brorson O, Brorson SH (1999)
An in vitro study of the susceptibility of mobile and cystic forms of Borrelia burgdorferi to metronidazole
APMIS, 107 (6), 566-76
DOI 10.1111/j.1699-0463.1999.tb01594.x, PubMed 10379684

Brorson SH (1999)
Comparison of the immunolabeling of heated and deplasticized epoxy sections on the electron microscopical level
Micron, 30 (4), 319-24
DOI 10.1016/s0968-4328(99)00030-x, PubMed 10431382

Brorson SH (1999)
Fixative-dependent increase in immunogold labeling following antigen retrieval on acrylic and epoxy sections
Biotech Histochem, 74 (5), 248-60
DOI 10.3109/10520299909034661, PubMed 10711505

Brorson SH, Andersen T, Haug S, Kristiansen I, Risstubben A, Tchou H, Ulstein J (1999)
Antigen retrieval on epoxy sections based on tissue infiltration with a moderately increased amount of accelerator to detect immune complex deposits in glomerular tissue
Histol Histopathol, 14 (1), 151-5
DOI 10.14670/HH-14.151, PubMed 9987660

Brorson SH, Halvorsen I, Lønning LC, Slaattun G, Sletten M, Rashid S (1999)
Increased yield of immunogold labeling of epoxy sections by adding para-phenylendiamine in the tissue processing
Micron, 30 (6), 561-6
DOI 10.1016/s0968-4328(99)00058-x, PubMed 10544504

Publications 1998

Brorson O, Brorson SH (1998)
In vitro conversion of Borrelia burgdorferi to cystic forms in spinal fluid, and transformation to mobile spirochetes by incubation in BSK-H medium
Infection, 26 (3), 144-50
DOI 10.1007/BF02771839, PubMed 9646104

Brorson O, Brorson SH (1998)
A rapid method for generating cystic forms of Borrelia burgdorferi, and their reversal to mobile spirochetes
APMIS, 106 (12), 1131-41
DOI 10.1111/j.1699-0463.1998.tb00269.x, PubMed 10052721

Brorson SH (1998)
Antigen detection on resin sections and methods for improving the immunogold labeling by manipulating the resin
Histol Histopathol, 13 (1), 275-81
DOI 10.14670/HH-13.275, PubMed 9476657

Brorson SH (1998)
The combination of high-accelerator epoxy resin and antigen retrieval to obtain more intense immunolabeling on epoxy sections than on LR-white sections for large proteins
Micron, 29 (2-3), 89-95
DOI 10.1016/s0968-4328(98)00010-9, PubMed 9684346

Brorson SH (1998)
Comparison of the immunogold labeling of single light chains and whole immunoglobulins with anti-kappa on LR-white and epoxy sections
Micron, 29 (6), 439-43
DOI 10.1016/s0968-4328(98)00024-9, PubMed 10071867

Brorson SH, Strøm EH (1998)
A new immunoelectron microscopy approach for the detection of immunoglobulin and complement deposits in epoxy-embedded renal biopsies
Ultrastruct Pathol, 22 (6), 449-57
DOI 10.3109/01913129809032281, PubMed 9891924

Publications 1997

Brorson O, Brorson SH (1997)
Transformation of cystic forms of Borrelia burgdorferi to normal, mobile spirochetes
Infection, 25 (4), 240-6
DOI 10.1007/BF01713153, PubMed 9266264

Brorson SH (1997)
How to examine the antigen-damaging effect of sodium ethoxide on deplasticized epoxy sections
J Histochem Cytochem, 45 (1), 143-6
DOI 10.1177/002215549704500117, PubMed 9010478

Brorson SH (1997)
Bovine serum albumin (BSA) as a reagent against non-specific immunogold labeling on LR-White and epoxy resin
Micron, 28 (3), 189-95
DOI 10.1016/s0968-4328(97)00030-9, PubMed 9332008

Brorson SH (1997)
Immunoelectron microscopy of resin embedded tissue: a study of the mechanisms for antigen detection with the aim of improving immunogold labeling of epoxy sections
Ullevål hospital, University of Oslo, Oslo, 1 b. (flere pag.)
BIBSYS 971699038, ISBN 82-994307-0-4

Brorson SH, Strøm EH, Skjørten F (1997)
Immunoelectron microscopy on epoxy sections without deplasticizing to detect glomerular immunoglobulin and complement deposits in renal diseases
APMIS, 105 (2), 139-49
DOI 10.1111/j.1699-0463.1997.tb00552.x, PubMed 9113076

Publications 1996

Brorson SH (1996)
Improved immunogold labeling of epoxy sections by the use of propylene oxide as additional agent in dehydration, infiltration and embedding
Micron, 27 (5), 345-53
DOI 10.1016/s0968-4328(96)00042-x, PubMed 9008875

Brorson SH, Skjørten F (1996)
The theoretical relationship of immunogold labeling on acrylic sections and epoxy sections
Micron, 27 (3-4), 193-201
DOI 10.1016/0968-4328(96)00034-0, PubMed 8953238

Brorson SH, Skjørten F (1996)
The theoretical ratio of immunogold labeling of deplasticized epoxy sections and acrylic sections
Micron, 27 (3-4), 203-9
DOI 10.1016/0968-4328(96)00033-9, PubMed 8953239

Brorson SH, Skjørten F (1996)
Improved technique for immunoelectron microscopy. How to prepare epoxy resin to obtain approximately the same immunogold labeling for epoxy sections as for acrylic sections without any etching
Micron, 27 (3-4), 211-7
DOI 10.1016/0968-4328(96)00029-7, PubMed 8953240

Publications 1995

Brorson SH, Skjørten F (1995)
Mechanism for antigen detection on deplasticized epoxy sections
Micron, 26 (4), 301-10
DOI 10.1016/0968-4328(95)00008-9, PubMed 8574521

Publications 1994

Brorson SH, Roos N, Skjørten F (1994)
Antibody penetration into LR-White sections
Micron, 25 (5), 453-60
DOI 10.1016/0968-4328(94)00035-2, PubMed 7850351

Publications 1993

Brorson SH (1993)
Postembedding immunelektronmikroskopi med særlig vekt på antistoffpenetrasjon i LR-WHITE innstøpningsplast
[S.-H. Brorson], Oslo, 1 b. (flere pag.)
BIBSYS 932202349

Publications 1992

Løberg EM, Brorson SH, Skjørten F, Torvik A (1992)
Neuronal uptake of plasma proteins in cryogenic brain lesions. An immunoelectron microscopic study
APMIS, 100 (11), 1033-40
DOI 10.1111/j.1699-0463.1992.tb04037.x, PubMed 1472362

Skjørten FJ, Brorson SH, Roald B, Strøm EH, Lund B (1992)
The use of post-embedding immunoelectron microscopy in the diagnosis of glomerular diseases. Comparison of immunoelectron microscopic and immunofluorescence studies
APMIS, 100 (11), 1001-7
DOI 10.1111/j.1699-0463.1992.tb04032.x, PubMed 1472359