Jan Mæhlen
- Professor; MD, PhD
Publications 2018
Evaluating different breast tumor progression models using screening data
BMC Cancer, 18 (1), 209
DOI 10.1186/s12885-018-4130-2, PubMed 29463227
Publications 2015
Staphylococcal α-hemolysin is neurotoxic and causes lysis of brain cells in vivo and in vitro
Neurotoxicology, 48, 61-7
DOI 10.1016/j.neuro.2015.03.001, PubMed 25757835
Apolipoprotein E allelotype is associated with neuropathological findings in Alzheimer's disease
Virchows Arch, 467 (2), 225-35
DOI 10.1007/s00428-015-1772-1, PubMed 25898889
Bias in Observational Studies of the Association between Menopausal Hormone Therapy and Breast Cancer
PLoS One, 10 (5), e0124076
DOI 10.1371/journal.pone.0124076, PubMed 25938446
Publications 2014
Breast cancer stromal elastosis is associated with mammography screening detection, low Ki67 expression and favourable prognosis in a population-based study
Diagn Pathol, 9, 230
DOI 10.1186/s13000-014-0230-8, PubMed 25522915
Brain infection with Staphylococcus aureus leads to high extracellular levels of glutamate, aspartate, γ-aminobutyric acid, and zinc
J Neurosci Res, 92 (12), 1792-800
DOI 10.1002/jnr.23444, PubMed 25043715
Loss of lysosomal membrane protein NCU-G1 in mice results in spontaneous liver fibrosis with accumulation of lipofuscin and iron in Kupffer cells
Dis Model Mech, 7 (3), 351-62
DOI 10.1242/dmm.014050, PubMed 24487409
Publications 2013
Postmortem heart weight: relation to body size and effects of cardiovascular disease and cancer
Cardiovasc Pathol, 23 (1), 5-11
DOI 10.1016/j.carpath.2013.09.001, PubMed 24121021
Unaltered lactate and glucose transporter levels in the MPTP mouse model of Parkinson's disease
J Parkinsons Dis, 3 (3), 371-85
DOI 10.3233/JPD-130190, PubMed 23963315
Publications 2012
The value of autopsies for determining the cause of death
Tidsskr Nor Laegeforen, 132 (2), 147-51
DOI 10.4045/tidsskr.11.0427, PubMed 22278269
The apolipoprotein E polymorphism and cardiovascular diseases--an autopsy study
Cardiovasc Pathol, 21 (6), 461-9
DOI 10.1016/j.carpath.2012.02.005, PubMed 22440829
Hormone therapy use and breast cancer incidence by histological subtypes in Sweden and Norway
Breast J, 18 (6), 549-56
DOI 10.1111/tbj.12001, PubMed 23002918
Overdiagnosis of breast cancer after 14 years of mammography screening
Tidsskr Nor Laegeforen, 132 (4), 414-7
DOI 10.4045/tidsskr.11.0195, PubMed 22353833
Publications 2011
Glucocorticoids dexamethasone and hydrocortisone inhibit proliferation and accelerate maturation of chicken cerebellar granule neurons
Brain Res, 1418, 32-41
DOI 10.1016/j.brainres.2011.08.053, PubMed 21925649
Why mammography screening has not lived up to expectations from the randomised trials
Cancer Causes Control, 23 (1), 15-21
DOI 10.1007/s10552-011-9867-8, PubMed 22072221
Surgical mortality at 30 days and complications leading to recraniotomy in 2630 consecutive craniotomies for intracranial tumors
Neurosurgery, 68 (5), 1259-68; discussion 1268-9
DOI 10.1227/NEU.0b013e31820c0441, PubMed 21273920
RESPONSE
Neuropathology, 31 (3), 307-308
DOI 10.1111/j.1440-1789.2011.01208.x
Effect of mammography screening on surgical treatment for breast cancer in Norway: comparative analysis of cancer registry data
BMJ, 343, d4692
DOI 10.1136/bmj.d4692, PubMed 21914765
Natural history of breast cancers detected in the Swedish mammography screening programme: a cohort study
Lancet Oncol, 12 (12), 1118-24
DOI 10.1016/S1470-2045(11)70250-9, PubMed 21996169
Publications 2010
[Better more than fewer autopsies]
Tidsskr Nor Laegeforen, 130 (11), 1121
DOI 10.4045/tidsskr.10.0469, PubMed 20531492
Proton magnetic resonance spectroscopy in the distinction of high-grade cerebral gliomas from single metastatic brain tumors
Acta Radiol, 51 (3), 316-25
DOI 10.3109/02841850903482901, PubMed 20092374
Brain pathology in fatal serotonin syndrome: presentation of two cases
Neuropathology, 31 (3), 265-70
DOI 10.1111/j.1440-1789.2010.01153.x, PubMed 20880320
[Breast cancer mortality versus breast cancer survival]
Tidsskr Nor Laegeforen, 130 (3), 261
DOI 10.4045/tidsskr.10.0033, PubMed 20160765
Publications 2009
Estimation of lead time and overdiagnosis in breast cancer screening
Br J Cancer, 100 (1), 219; author reply 220
DOI 10.1038/sj.bjc.6604762, PubMed 19127274
IGFBP3 colocalizes with and regulates hypocretin (orexin)
PLoS One, 4 (1), e4254
DOI 10.1371/journal.pone.0004254, PubMed 19158946
Tuberculin status, socioeconomic differences and differences in all-cause mortality: experience from Norwegian cohorts born 1910-49
Int J Epidemiol, 38 (2), 427-34
DOI 10.1093/ije/dyn347, PubMed 19339259
In situ deposition of complement in human acute brain ischaemia
Scand J Immunol, 69 (6), 555-62
DOI 10.1111/j.1365-3083.2009.02253.x, PubMed 19439017
Quantitative apparent diffusion coefficients in the characterization of brain tumors and associated peritumoral edema
Acta Radiol, 50 (6), 682-9
DOI 10.1080/02841850902933123, PubMed 19449234
Declining breast cancer incidence and decreased HRT use
Lancet, 373 (9662), 460-1; author reply 461
DOI 10.1016/S0140-6736(09)60166-5, PubMed 19200913
Breast Cancer Overdiagnosis With Screening Mammography Reply
Arch. Intern. Med., 169 (10), 1000-1001
DOI 10.1001/archinternmed.2009.96
Publications 2008
Low-potency glucocorticoid hydrocortisone has similar neurotoxic effects as high-potency glucocorticoid dexamethasone on neurons in the immature chicken cerebellum
Brain Res, 1236, 39-48
DOI 10.1016/j.brainres.2008.07.095, PubMed 18706896
Flawed inferences about screening mammography's benefit based on observational data
J Clin Oncol, 27 (4), 639-40; author reply 641-2
DOI 10.1200/JCO.2008.17.9341, PubMed 19075270
Biases in estimates of overdetection due to mammography screening
Lancet Oncol, 9 (3), 199-201; author reply 201-2
DOI 10.1016/S1470-2045(08)70049-4, PubMed 18308246
The natural history of invasive breast cancers detected by screening mammography
Arch Intern Med, 168 (21), 2311-6
DOI 10.1001/archinte.168.21.2311, PubMed 19029493
Publications 2007
Listeriosis in Norway 1977-2003
Scand J Infect Dis, 39 (5), 398-404
DOI 10.1080/00365540601087574, PubMed 17464861
Undeclared motives in withdrawing a publication
Lancet, 369 (9574), 1690
DOI 10.1016/S0140-6736(07)60772-7, PubMed 17512849
Fatal subarachnoidal haemorrhage in a Norwegian traveller with dengue virus infection
Scand J Infect Dis, 39 (3), 272-4
DOI 10.1080/00365540600891307, PubMed 17366065
Constant relative survival rates in Sweden and Norway when adjusting for screening-related overdiagnosis
Int J Cancer, 120 (10), 2279; author reply 2280
DOI 10.1002/ijc.22497, PubMed 17230530
[Is overdiagnosing with 50 percent in mammography screening acceptable?]
Tidsskr Nor Laegeforen, 127 (2), 207-8; author reply 208
PubMed 17237877
A decline in breast-cancer incidence
N Engl J Med, 357 (5), 510-1; author reply 513
PubMed 17674462
Publications 2006
Preconditioning with estradiol abolishes its neuroprotection in cerebellar neurons
Biochem Biophys Res Commun, 352 (4), 966-72
DOI 10.1016/j.bbrc.2006.11.139, PubMed 17157803
What is publication?
Lancet, 368 (9550), 1854-6
DOI 10.1016/S0140-6736(06)69756-0, PubMed 17126704
Chicken cerebellar granule neurons rapidly develop excitotoxicity in culture
J Neurosci Methods, 156 (1-2), 129-35
DOI 10.1016/j.jneumeth.2006.02.012, PubMed 16564575
Cathepsin D deficiency underlies congenital human neuronal ceroid-lipofuscinosis
Brain, 129 (Pt 6), 1438-45
DOI 10.1093/brain/awl107, PubMed 16670177
Results of the Two-County trial of mammography screening are not compatible with contemporaneous official Swedish breast cancer statistics
Dan Med Bull, 53 (4), 438-40
PubMed 17150148
WITHDRAWN: Results of the Two-County trial of mammography screening are not compatible with contemporaneous official Swedish breast cancer statistics
Eur J Cancer (in press)
DOI 10.1016/j.ejca.2005.12.016, PubMed 16530407
Do model results suggest spontaneous regression of breast cancer?
Int J Cancer, 118 (10), 2647; author reply 2649
DOI 10.1002/ijc.21634, PubMed 16380989
Ramifications of screening for breast cancer: definition of overdiagnosis is confusing in follow-up of Malmö trial
BMJ, 332 (7543), 727-8
DOI 10.1136/bmj.332.7543.727-b, PubMed 16565134
Publications 2005
Brain stem encephalitis in listeriosis
Scand J Infect Dis, 37 (3), 190-4
DOI 10.1080/00365540410020938, PubMed 15849051
Neuropathological findings in 9 cases of listeria monocytogenes brain stem encephalitis
Brain Pathol, 15 (3), 187-91
DOI 10.1111/j.1750-3639.2005.tb00519.x, PubMed 16196384
[Estrogen replacement therapy and breast cancer]
Tidsskr Nor Laegeforen, 125 (8), 1045; author reply 1045
PubMed 15852091
Reduction in mortality from breast cancer: decrease with screening was marked in younger age group
BMJ, 330 (7498), 1024; author reply 1025
DOI 10.1136/bmj.330.7498.1024, PubMed 15860834
Model of outcomes of screening mammography: spontaneous regression of breast cancer may not be uncommon
BMJ, 331 (7512), 350; author reply 351
DOI 10.1136/bmj.331.7512.350-a, PubMed 16081453
Publications 2004
Spontaneous regression of cancerous tumors detected by mammography screening
JAMA, 292 (21), 2579-80; author reply 2580
DOI 10.1001/jama.292.21.2579, PubMed 15572712
[Overdiagnosis in mammography screening]
Tidsskr Nor Laegeforen, 124 (17), 2238-9
PubMed 15356688
Incidence of breast cancer in Norway and Sweden during introduction of nationwide screening: prospective cohort study
BMJ, 328 (7445), 921-4
DOI 10.1136/bmj.38044.666157.63, PubMed 15013948
Publications 2002
Early psychomotor slowing predicts the development of HIV dementia and autopsy-verified HIV encephalitis
Acta Neurol Scand, 105 (4), 270-5
DOI 10.1034/j.1600-0404.2002.9o188.x, PubMed 12004769
Allele frequencies of apolipoprotein E gene polymorphisms in the protein coding region and promoter region (-491A/T) in a healthy Norwegian population
Hum Biol, 74 (1), 137-42
DOI 10.1353/hub.2002.0006, PubMed 11931575
Publications 2001
Evidence for intraaxonal spread of Listeria monocytogenes from the periphery to the central nervous system
Brain Pathol, 11 (4), 432-8
DOI 10.1111/j.1750-3639.2001.tb00411.x, PubMed 11556688
Myointimal hyperplasia and sympathetic reinnervation following local cold injury and rapid rewarming in the rabbit central ear artery
Vasa, 30 (3), 176-83
DOI 10.1024/0301-1526.30.3.176, PubMed 11582947
Dementia in AIDS patients in Oslo; the role of HIV encephalitis and CMV encephalitis
Scand J Infect Dis, 33 (10), 755-8
DOI 10.1080/003655401317074572, PubMed 11728043
[South American blastomycosis--a differential diagnosis to tuberculous meningitis]
Tidsskr Nor Laegeforen, 121 (1), 33-4
PubMed 12013613
Progressive facial hemiatrophy associated with an astrocytoma in the cerebellopontine region
J Oral Maxillofac Surg, 59 (6), 684-7
DOI 10.1053/joms.2001.23404, PubMed 11381396
The apolipoprotein E epsilon4 allele is no risk factor for prostate cancer in the Norwegian population
Br J Cancer, 85 (9), 1418
DOI 10.1054/bjoc.2001.2098, PubMed 11720484
[Norwegian breast cancer mortality rates and validity of Swedish mammographic studies]
Tidsskr Nor Laegeforen, 121 (16), 1928-31
PubMed 11488185
Publications 2000
[The olfactory sense]
Tidsskr Nor Laegeforen, 120 (30), 3719-25
PubMed 11215945
Association between apolipoprotein E genotypes and cancer risk in patients with acquired immunodeficiency syndrome
Cancer Detect Prev, 24 (5), 496-9
PubMed 11129992
[Will the revolutionary knowledge of apoptosis play an important role in medicine?]
Lakartidningen, 97 (12), 1389-93
PubMed 10765620
[Will the revolutionary knowledge of apoptosis play an important role in medicine?]
Tidsskr Nor Laegeforen, 120 (1), 57-61
PubMed 10815481
Injectional anthrax in a heroin skin-popper
Lancet, 356 (9241), 1574-5
DOI 10.1016/s0140-6736(00)03133-0, PubMed 11075776
Injectional anthrax in a heroin skin-popper
In Lancet, Lancet Ltd., London, 356(2000)nr 9241, s.1574-1575
BIBSYS 01078134x
Sannsynlig systematisk anthrax hos stoffmisbrukere i Oslokrever oppmerksomhet
In MSIS-rapport, Nasjonalt folkehelseinstitutt, Avdeling for infeksjonsovervåking, Oslo, 28(2000)nr 17, s.1
BIBSYS 010781404
Publications 1999
[Brain stem infection caused by Listeria monocytogenes]
Tidsskr Nor Laegeforen, 119 (3), 373-4
PubMed 10074834
Early and late functional and histopathological perturbations in the rabbit ear-artery following local cold injury
Vasa, 28 (2), 85-94
DOI 10.1024/0301-1526.28.2.85, PubMed 10409918
[The amyloid and tau hypothesis in degenerative dementia]
Tidsskr Nor Laegeforen, 119 (7), 976-9
PubMed 10210960
Denervation enhances spontaneous inflammatory myopathy in SJL mice
Muscle Nerve, 22 (7), 883-8
DOI 10.1002/(sici)1097-4598(199907)22:7<883::aid-mus11>3.0.co;2-k, PubMed 10398206
[Listeria monocytogenes--the perfect parasite?]
Tidsskr Nor Laegeforen, 119 (3), 375-9
PubMed 10074835
Publications 1998
Kaposi's sarcoma and protection from HIV dementia
Science, 280 (5362), 361-2
PubMed 9575077
Kaposi's sarcoma and protection from HIV dementia
Science, 280 (5362), 361-362
Publications 1997
HIV dementia and apolipoprotein E
Acta Neurol Scand, 95 (5), 315-8
DOI 10.1111/j.1600-0404.1997.tb00217.x, PubMed 9188909
The impact of primary central nervous system lymphoma in AIDS patients: a population-based autopsy study from Oslo
J Acquir Immune Defic Syndr Hum Retrovirol, 14 (4), 351-4
DOI 10.1097/00042560-199704010-00007, PubMed 9111477
[Splenic atrophy and fatal pneumococcal infection in inflammatory bowel disease]
Tidsskr Nor Laegeforen, 117 (13), 1900-1
PubMed 9214010
[1997 Nobel Prize in physiology or medicine]
Tidsskr Nor Laegeforen, 117 (30), 4358-9
PubMed 9456573
Publications 1996
High incidence and aggressive growth of non-AIDS-defining cancers among AIDS patients in Oslo
APMIS, 104 (10), 729-33
DOI 10.1111/j.1699-0463.1996.tb04935.x, PubMed 8980623
Publications 1995
Changing incidence of HIV-induced brain lesions in Oslo, 1983-1994: effects of zidovudine treatment
AIDS, 9 (10), 1165-9
DOI 10.1097/00002030-199510000-00008, PubMed 8519453
Retrograde axonal cytokine transport: a pathway for immunostimulation in the brain inducing hypoxia and sudden infant death?
Med Hypotheses, 44 (2), 81-4
DOI 10.1016/0306-9877(95)90074-8, PubMed 7541103
Publications 1994
Nerve-evoked electrical activity regulates molecules and cells with immunological function in rat muscle tissue
Eur J Neurosci, 6 (7), 1113-8
DOI 10.1111/j.1460-9568.1994.tb00608.x, PubMed 7952291
Publications 1993
A model of selective synapse formation in sympathetic ganglia
J Neurobiol, 24 (3), 263-79
DOI 10.1002/neu.480240302, PubMed 8492106
A model of selective synapse formation in sympathetic ganglia
In Journal of neurobiology, Wiley, New York, 24(1993), S. 263-279
BIBSYS 071821430
Publications 1992
Persistent changes in behaviour and brain serotonin during ageing in rats subjected to infant nasal virus infection
Neurobiol Aging, 13 (1), 83-7
DOI 10.1016/0197-4580(92)90013-n, PubMed 1347403
Affection of the hippocampal granule cells in pontosubicular neuron necrosis
Acta Neuropathol, 83 (5), 535-7
DOI 10.1007/BF00310032, PubMed 1621509
Publications 1991
Paramyxovirus infections alter certain functional properties in cultured sensory neurons
Brain Res, 540 (1-2), 123-30
DOI 10.1016/0006-8993(91)90498-k, PubMed 1647243
POSTMORTEM FINDINGS IN 2 PATIENTS WITH THE CARBOHYDRATE-DEFICIENT GLYCOPROTEIN SYNDROME
ACTA PAEDIATR SCAND (375), 55-62
[The carbohydrate deficient glycoprotein syndrome]
Tidsskr Nor Laegeforen, 111 (10), 1236-7
PubMed 2042132
Publications 1990
Necrosis of granule cells of hippocampus in adrenocortical failure
Acta Neuropathol, 80 (1), 85-7
DOI 10.1007/BF00294226, PubMed 2360419
Behavioural deficits and serotonin depletion in adult rats after transient infant nasal viral infection
Neuroscience, 35 (2), 355-63
DOI 10.1016/0306-4522(90)90089-m, PubMed 1696362
[The pathogenesis of Alzheimer's disease--what do we know today?]
Tidsskr Nor Laegeforen, 110 (13), 1715-7
PubMed 2368056
Publications 1989
Distribution of leukosialin (W3/13)-like immunoreactivity in the rat central nervous system
J Neurocytol, 18 (1), 71-6
DOI 10.1007/BF01188425, PubMed 2523471
SELECTIVITY OF SYNAPSE FORMATION DURING DEVELOPMENT IN VERTEBRATES
FORTS ZOOL, 37, 46-55
Peripheral nerve injury causes transient expression of MHC class I antigens in rat motor neurons and skeletal muscles
Brain Res, 481 (2), 368-72
DOI 10.1016/0006-8993(89)90816-0, PubMed 2720389
Persistence of measles virus in rat brain neurons is promoted by depletion of CD8+ T cells
J Neuroimmunol, 21 (2-3), 149-55
DOI 10.1016/0165-5728(89)90170-7, PubMed 2783583
Local enhancement of major histocompatibility complex (MHC) class I and II expression and cell infiltration in experimental allergic encephalomyelitis around axotomized motor neurons
J Neuroimmunol, 23 (2), 125-32
DOI 10.1016/0165-5728(89)90031-3, PubMed 2786005
Gamma-interferon-like immunoreactivity in axotomized rat motor neurons
J Neurosci, 9 (11), 3870-5
DOI 10.1523/JNEUROSCI.09-11-03870.1989, PubMed 2511280
Early major histocompatibility complex (MHC) class I antigen induction in hypothalamic supraoptic and paraventricular nuclei in trypanosome-infected rats
J Neuroimmunol, 24 (1-2), 105-12
DOI 10.1016/0165-5728(89)90104-5, PubMed 2681260
Publications 1988
Axotomy induces MHC class I antigen expression on rat nerve cells
Neurosci Lett, 92 (1), 8-13
DOI 10.1016/0304-3940(88)90733-1, PubMed 3185980
Measles virus infection causes expression of class I and class II MHC antigens in rat brain
Ann N Y Acad Sci, 540 (1), 486-7
DOI 10.1111/j.1749-6632.1988.tb27144.x, PubMed 3061345
Publications 1987
Two types of synaptic selectivity and their interrelation during sprouting in the guinea-pig superior cervical ganglion
J Physiol, 384, 233-45
DOI 10.1113/jphysiol.1987.sp016452, PubMed 3656146
Two types of synaptic selectivity and their interrelationduring sprouting in the guinea-pig superior cervical ganglion
In Journal of physiology, Cambridge University Press, Cambridge, 384(1987), S. 233-245
BIBSYS 071831762
Induction of class I and class II transplantation antigens in rat brain during fatal and non-fatal measles virus infection
J Neuroimmunol, 16 (2), 215-24
DOI 10.1016/0165-5728(87)90076-2, PubMed 3497946
Publications 1986
SELECTIVE SYNAPTIC CONNECTIONS - SIGNIFICANCE OF RECOGNITION AND COMPETITION IN MATURE SYMPATHETIC-GANGLIA
Trends Neurosci., 9 (1), 21-24
Publications 1985
The selective innervation of guinea-pig superior cervical ganglion cells by sprouts from intact preganglionic axons
J Physiol, 358, 239-53
DOI 10.1113/jphysiol.1985.sp015549, PubMed 3981467
The selective innervation of guinea-pig superior cervicalganglion cells by sprouts from intact preganglionic axons
In Journal of physiology, Cambridge University Press, Cambridge, 358(1985), S. 239-253
BIBSYS 071821031
Publications 1984
Functional, structural and chemical correlates of sprouting of intact preganglionic sympathetic axons in the guinea-pig
J Physiol, 347, 741-9
DOI 10.1113/jphysiol.1984.sp015093, PubMed 6707975
Rearrangement of synapses on guinea-pig sympathetic ganglion cells after partial interruption of the preganglionic nerve
J Physiol, 348, 43-56
DOI 10.1113/jphysiol.1984.sp015098, PubMed 6716290
Publications 1982
The effects of electrical stimulation on sprouting after partial denervation of guinea-pig sympathetic ganglion cells
J Physiol, 322, 151-66
DOI 10.1113/jphysiol.1982.sp014029, PubMed 7069612
Publications 1981
Selective synapse formation during sprouting after partial denervation of the guinea-pig superior cervical ganglion
J Physiol, 319, 555-67
DOI 10.1113/jphysiol.1981.sp013926, PubMed 7320928