Øystein Garred
- Consultant; MD, PhD
Publications 2020
Integrated differential DNA methylation and gene expression of formalin-fixed paraffin-embedded uveal melanoma specimens identifies genes associated with early metastasis and poor prognosis
Exp Eye Res, 203, 108426 (in press)
DOI 10.1016/j.exer.2020.108426, PubMed 33387485
Coagulation factor V is a marker of tumor-infiltrating immune cells in breast cancer
Oncoimmunology, 9 (1), 1824644
DOI 10.1080/2162402X.2020.1824644, PubMed 33457104
Immune phenotype of tumor microenvironment predicts response to bevacizumab in neoadjuvant treatment of ER-positive breast cancer
Int J Cancer, 147 (9), 2515-2525
DOI 10.1002/ijc.33108, PubMed 32488909
Publications 2019
Assessing Treatment Response and Prognosis by Serum and Tissue Metabolomics in Breast Cancer Patients
J Proteome Res, 18 (10), 3649-3660
DOI 10.1021/acs.jproteome.9b00316, PubMed 31483662
Breast cancer quantitative proteome and proteogenomic landscape
Nat Commun, 10 (1), 1600
DOI 10.1038/s41467-019-09018-y, PubMed 30962452
Toward Personalized Computer Simulation of Breast Cancer Treatment: A Multiscale Pharmacokinetic and Pharmacodynamic Model Informed by Multitype Patient Data
Cancer Res, 79 (16), 4293-4304
DOI 10.1158/0008-5472.CAN-18-1804, PubMed 31118201
Serum levels of inflammation-related markers and metabolites predict response to neoadjuvant chemotherapy with and without bevacizumab in breast cancers
Int J Cancer, 146 (1), 223-235
DOI 10.1002/ijc.32638, PubMed 31444972
An independent poor-prognosis subtype of breast cancer defined by a distinct tumor immune microenvironment
Nat Commun, 10 (1), 5499
DOI 10.1038/s41467-019-13329-5, PubMed 31796750
Publications 2018
Time series analysis of neoadjuvant chemotherapy and bevacizumab-treated breast carcinomas reveals a systemic shift in genomic aberrations
Genome Med, 10 (1), 92
DOI 10.1186/s13073-018-0601-y, PubMed 30497530
Subtype-specific clinical and prognostic relevance of tumor-expressed F5 and regulatory F5 variants in breast cancer: the CoCaV study
J Thromb Haemost, 16 (7), 1347-1356
DOI 10.1111/jth.14151, PubMed 29766637
Publications 2017
Evaluation of metabolomic changes during neoadjuvant chemotherapy combined with bevacizumab in breast cancer using MR spectroscopy
Metabolomics, 13 (4), 37
Multicellular tumor spheroids of human uveal melanoma induce genes associated with anoikis resistance, lipogenesis, and SSXs
Mol Vis, 23, 680-694
PubMed 29033534
The Longitudinal Transcriptional Response to Neoadjuvant Chemotherapy with and without Bevacizumab in Breast Cancer
Clin Cancer Res, 23 (16), 4662-4670
DOI 10.1158/1078-0432.CCR-17-0160, PubMed 28487444
Inflammation of mammary adipose tissue occurs in overweight and obese patients exhibiting early-stage breast cancer (vol 3, 35, 2017)
npj Breast Cancer, 3, 35
Erratum: Inflammation of mammary adipose tissue occurs in overweight and obese patients exhibiting early-stage breast cancer
NPJ Breast Cancer, 3, 35
DOI 10.1038/s41523-017-0030-x, PubMed 28884144
Inflammation of mammary adipose tissue occurs in overweight and obese patients exhibiting early-stage breast cancer
NPJ Breast Cancer, 3, 19
DOI 10.1038/s41523-017-0015-9, PubMed 28649659
Publications 2016
Lipoprotein subfractions by nuclear magnetic resonance are associated with tumor characteristics in breast cancer
Lipids Health Dis, 15, 56
DOI 10.1186/s12944-016-0225-4, PubMed 26970778
Metabolic clusters of breast cancer in relation to gene- and protein expression subtypes
Cancer Metab, 4, 12
DOI 10.1186/s40170-016-0152-x, PubMed 27350877
Direct Transcriptional Consequences of Somatic Mutation in Breast Cancer
Cell Rep, 16 (7), 2032-46
DOI 10.1016/j.celrep.2016.07.028, PubMed 27498871
Determinants of acquired activated protein C resistance and D-dimer in breast cancer
Thromb Res, 145, 78-83
DOI 10.1016/j.thromres.2016.08.003, PubMed 27505249
Publications 2015
Bilateral uveal melanomas with different gene expression detected with 7 years interval
Acta Ophthalmol, 94 (1), 99-102
DOI 10.1111/aos.12857, PubMed 26496992
Publications 2014
Breast cancer stromal elastosis is associated with mammography screening detection, low Ki67 expression and favourable prognosis in a population-based study
Diagn Pathol, 9, 230
DOI 10.1186/s13000-014-0230-8, PubMed 25522915
Increased coagulation activity and genetic polymorphisms in the F5, F10 and EPCR genes are associated with breast cancer: a case-control study
BMC Cancer, 14, 845
DOI 10.1186/1471-2407-14-845, PubMed 25407022
Publications 2007
Structural requirements for furin-induced cleavage and activation of Shiga toxin
Biochem Biophys Res Commun, 357 (1), 144-9
DOI 10.1016/j.bbrc.2007.03.110, PubMed 17407762
Publications 2006
Assessing invasion criteria in fine needle aspirates from breast carcinoma diagnosed as DICS or invasive carcinoma: can we identify an invasive component in addition to DCIS?
Acta Cytol, 50 (3), 263-70
DOI 10.1159/000325952, PubMed 16780019
Publications 2005
EGFR gene copy number heterogeneity in fine-needle aspiration cytology from breast carcinomas determined by chromogenic in situ hybridization
Diagn Cytopathol, 33 (4), 228-32
DOI 10.1002/dc.20338, PubMed 16138375
Cytologic features of ductal carcinoma in situ in fine-needle aspiration of the breast mirror the histopathologic growth pattern heterogeneity and grading
Cancer, 105 (1), 21-7
DOI 10.1002/cncr.20735, PubMed 15593325
Publications 2001
Reconstitution of clathrin-independent endocytosis at the apical domain of permeabilized MDCK II cells: requirement for a Rho-family GTPase
Traffic, 2 (1), 26-36
DOI 10.1034/j.1600-0854.2001.020105.x, PubMed 11208166
Publications 2000
Apical endocytosis of ricin in MDCK cells is regulated by the cyclooxygenase pathway
J Cell Sci, 113 ( Pt 7), 1213-21
PubMed 10704372
Apical macropinocytosis in polarized MDCK cells: regulation by N-ethylmaleimide-sensitive proteins
Eur J Cell Biol, 79 (7), 447-57
DOI 10.1078/0171-9335-00071, PubMed 10961444
Publications 1999
Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles
Mol Biol Cell, 10 (4), 961-74
DOI 10.1091/mbc.10.4.961, PubMed 10198050
Publications 1997
Entry of Shiga toxin into cells: intracellular transport of protein toxins
Department of Biochemistry, Institute for Cancer Research, The Norwegian Radium Hospital, Medical Faculty, University of Oslo, [Oslo], 1 b. (flere pag.)
BIBSYS 972822852, ISBN 82-7633-099-1
Role of the disulfide bond in Shiga toxin A-chain for toxin entry into cells
J Biol Chem, 272 (17), 11414-9
DOI 10.1074/jbc.272.17.11414, PubMed 9111051
[Self-inhibiting N-glycosidase activity of shigella toxin]
Mol Biol (Mosk), 31 (3), 528-35
PubMed 9297098
Self-inhibition of N-glycosidase activity of shiga toxin
Mol. Biol., 31 (3), 441-447
Intracellular transport and processing of protein toxins produced by enteric bacteria
Adv Exp Med Biol, 412, 225-32
DOI 10.1007/978-1-4899-1828-4_34, PubMed 9192018
Publications 1996
Effect of calmodulin antagonists on endocytosis and intracellular transport of ricin in polarized MDCK cells
Exp Cell Res, 227 (2), 298-308
DOI 10.1006/excr.1996.0279, PubMed 8831568
Thapsigargin-induced transport of cholera toxin to the endoplasmic reticulum
Proc Natl Acad Sci U S A, 93 (22), 12339-43
DOI 10.1073/pnas.93.22.12339, PubMed 8901582
Importance of glycolipid synthesis for butyric acid-induced sensitization to shiga toxin and intracellular sorting of toxin in A431 cells
Mol Biol Cell, 7 (9), 1391-404
DOI 10.1091/mbc.7.9.1391, PubMed 8885234
Publications 1995
Role of processing and intracellular transport for optimal toxicity of Shiga toxin and toxin mutants
Exp Cell Res, 218 (1), 39-49
DOI 10.1006/excr.1995.1128, PubMed 7737376
Furin-induced cleavage and activation of Shiga toxin
J Biol Chem, 270 (18), 10817-21
DOI 10.1074/jbc.270.18.10817, PubMed 7738018
Diphtheria toxin endocytosis and membrane translocation are dependent on the intact membrane-anchored receptor (HB-EGF precursor): studies on the cell-associated receptor cleaved by a metalloprotease in phorbol-ester-treated cells
Biochem J, 310 ( Pt 1), 285-9
DOI 10.1042/bj3100285, PubMed 7646457
Publications 1994
ENTRY OF SHIGA TOXIN INTO CELLS
INT CONGR SER, 1072, 139-146
Retrograde transport from the Golgi complex to the ER of both Shiga toxin and the nontoxic Shiga B-fragment is regulated by butyric acid and cAMP
J Cell Biol, 126 (1), 53-64
DOI 10.1083/jcb.126.1.53, PubMed 8027186
Publications 1993
Entry of Shiga toxin into cells
Zentralbl Bakteriol, 278 (2-3), 296-305
DOI 10.1016/s0934-8840(11)80846-7, PubMed 8347933
Endocytosis and intracellular transport of protein toxins
Biochem Soc Trans, 21 ( Pt 3) (3), 707-11
DOI 10.1042/bst0210707, PubMed 8224494
Publications 1992
Protein toxins: mode of action and cell entry
Biochem Soc Trans, 20 (4), 724-7
DOI 10.1042/bst0200724, PubMed 1487049
Retrograde transport of endocytosed Shiga toxin to the endoplasmic reticulum
Nature, 358 (6386), 510-2
DOI 10.1038/358510a0, PubMed 1641040