Publications 2023

Bråten LCH, Gjefsen E, Gervin K, Pripp AH, Skouen JS, Schistad E, Pedersen LM, Wigemyr M, Selmer KK, Aass HCD, Goll G, Brox JI, Espeland A, Grøvle L, Zwart JA, Storheim K, AIM-study group (2023)
Cytokine Patterns as Predictors of Antibiotic Treatment Effect in Chronic Low Back Pain with Modic Changes: Subgroup Analyses of a Randomized Trial (AIM Study)
J Pain Res, 16, 1713-1724
DOI 10.2147/JPR.S406079, PubMed 37252109

Vigeland MD, Flåm ST, Vigeland MD, Espeland A, Zucknick M, Wigemyr M, Bråten LCH, Gjefsen E, Zwart JA, Storheim K, Pedersen LM, Selmer K, Lie BA, Gervin K, The Aim Study Group (2023)
Long-Term Use of Amoxicillin Is Associated with Changes in Gene Expression and DNA Methylation in Patients with Low Back Pain and Modic Changes
Antibiotics (Basel), 12 (7)
DOI 10.3390/antibiotics12071217, PubMed 37508313

Publications 2022

Lie MU, Pedersen LM, Heuch I, Winsvold B, Gjerstad J, Hasvik E, Nygaard ØP, Grotle M, Matre D, Zwart JA, Nilsen KB (2022)
Low Back Pain With Persistent Radiculopathy; the Clinical Role of Genetic Variants in the Genes SOX5, CCDC26/GSDMC and DCC
Front Genet, 12, 757632
DOI 10.3389/fgene.2021.757632, PubMed 35140737

Vigeland MD, Flåm ST, Vigeland MD, Espeland A, Kristoffersen PM, Vetti N, Wigemyr M, Bråten LCH, Gjefsen E, Schistad EI, Haugen AJ, Froholdt A, Skouen JS, Zwart JA, Storheim K, Pedersen LM, Lie BA, AIM Study Group (2022)
Correlation between gene expression and MRI STIR signals in patients with chronic low back pain and Modic changes indicates immune involvement
Sci Rep, 12 (1), 215
DOI 10.1038/s41598-021-04189-5, PubMed 34997115

Wightman DP, Jansen IE, Savage JE, Shadrin AA, Bahrami S, Holland D, Rongve A, Børte S, Winsvold BS, Drange OK, Martinsen AE, Skogholt AH, Willer C, Bråthen G, Bosnes I, Nielsen JB, Fritsche LG, Thomas LF, Pedersen LM, Gabrielsen ME, Johnsen MB, Meisingset TW, Zhou W, Proitsi P, Hodges A et al. (2022)
Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease
Nat Genet, 54 (7), 1062
DOI 10.1038/s41588-022-01126-8, PubMed 35726068

Publications 2021

Gjefsen E, Gervin K, Goll G, Bråten LCH, Wigemyr M, Aass HCD, Vigeland MD, Schistad E, Pedersen LM, Pripp AH, Storheim K, Selmer KK, Zwart JA (2021)
Macrophage migration inhibitory factor: a potential biomarker for chronic low back pain in patients with Modic changes
RMD Open, 7 (2)
DOI 10.1136/rmdopen-2021-001726, PubMed 34344830

Wightman DP, Jansen IE, Savage JE, Shadrin AA, Bahrami S, Holland D, Rongve A, Børte S, Winsvold BS, Drange OK, Martinsen AE, Skogholt AH, Willer C, Bråthen G, Bosnes I, Nielsen JB, Fritsche LG, Thomas LF, Pedersen LM, Gabrielsen ME, Johnsen MB, Meisingset TW, Zhou W, Proitsi P, Hodges A et al. (2021)
A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease
Nat Genet, 53 (9), 1276-1282
DOI 10.1038/s41588-021-00921-z, PubMed 34493870

Wightman DP, Jansen IE, Savage JE, Shadrin AA, Bahrami S, Holland D, Rongve A, Børte S, Winsvold BS, Drange OK, Martinsen AE, Skogholt AH, Willer C, Bråthen G, Bosnes I, Nielsen JB, Fritsche LG, Thomas LF, Pedersen LM, Gabrielsen ME, Johnsen MB, Meisingset TW, Zhou W, Proitsi P, Hodges A et al. (2021)
Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease
Nat Genet, 53 (12), 1722
DOI 10.1038/s41588-021-00977-x, PubMed 34773122

Publications 2020

Lie MU, Winsvold B, Gjerstad J, Matre D, Pedersen LM, Heuch I, Zwart JA, Nilsen KB (2020)
The association between selected genetic variants and individual differences in experimental pain
Scand J Pain, 21 (1), 163-173
DOI 10.1515/sjpain-2020-0091, PubMed 33108341

Publications 2019

Fjeld OR, Grotle M, Matre D, Pedersen LM, Lie MU, Småstuen MC, Storheim K, Heuch I, Stubhaug A, Zwart JA, Nilsen KB (2019)
Predicting the outcome of persistent sciatica using conditioned pain modulation: 1-year results from a prospective cohort study
Scand J Pain, 20 (1), 69-75
DOI 10.1515/sjpain-2019-0112, PubMed 31527299

Publications 2017

Fjeld O, Grotle M, Siewers V, Pedersen LM, Nilsen KB, Zwart JA (2017)
Prognostic Factors for Persistent Leg-Pain in Patients Hospitalized With Acute Sciatica
Spine (Phila Pa 1976), 42 (5), E272-E279
DOI 10.1097/BRS.0000000000001773, PubMed 28244968

Storheim K, Espeland A, Grøvle L, Skouen JS, Aßmus J, Anke A, Froholdt A, Pedersen LM, Haugen AJ, Fors T, Schistad E, Lutro O, Marchand GH, Kadar T, Vetti N, Randen S, Nygaard ØP, Brox JI, Grotle M, Zwart JA (2017)
Antibiotic treatment In patients with chronic low back pain and Modic changes (the AIM study): study protocol for a randomised controlled trial
Trials, 18 (1), 596
DOI 10.1186/s13063-017-2306-8, PubMed 29246188

Valeberg BT, Pedersen LM, Girotto V, Christensen VL, Stubhaug A (2017)
Validation of the Norwegian Pain Sensitivity Questionnaire
J Pain Res, 10, 1137-1142
DOI 10.2147/JPR.S129540, PubMed 28553134

Publications 2016

Gormley P, Anttila V, Winsvold BS, Palta P, Esko T, Pers TH, Farh KH, Cuenca-Leon E, Muona M, Furlotte NA, Kurth T, Ingason A, McMahon G, Ligthart L, Terwindt GM, Kallela M, Freilinger TM, Ran C, Gordon SG, Stam AH, Steinberg S, Borck G, Koiranen M, Quaye L, Adams HH et al. (2016)
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine
Nat Genet, 48 (8), 856-66
DOI 10.1038/ng.3598, PubMed 27322543

Gormley P, Anttila V, Winsvold BS, Palta P, Esko T, Pers TH, Farh KH, Cuenca-Leon E, Muona M, Furlotte NA, Kurth T, Ingason A, McMahon G, Ligthart L, Terwindt GM, Kallela M, Freilinger TM, Ran C, Gordon SG, Stam AH, Steinberg S, Borck G, Koiranen M, Quaye L, Adams HH et al. (2016)
Corrigendum: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine
Nat Genet, 48 (10), 1296
DOI 10.1038/ng1016-1296c, PubMed 27681292

Publications 2015

Pedersen LM, Schistad E, Jacobsen LM, Røe C, Gjerstad J (2015)
Serum levels of the pro-inflammatory interleukins 6 (IL-6) and -8 (IL-8) in patients with lumbar radicular pain due to disc herniation: A 12-month prospective study
Brain Behav Immun, 46, 132-6
DOI 10.1016/j.bbi.2015.01.008, PubMed 25653193

Winsvold BS, Nelson CP, Malik R, Gormley P, Anttila V, Vander Heiden J, Elliott KS, Jacobsen LM, Palta P, Amin N, de Vries B, Hämäläinen E, Freilinger T, Ikram MA, Kessler T, Koiranen M, Ligthart L, McMahon G, Pedersen LM, Willenborg C, Won HH, Olesen J, Artto V, Assimes TL, Blankenberg S et al. (2015)
Genetic analysis for a shared biological basis between migraine and coronary artery disease
Neurol Genet, 1 (1), e10
DOI 10.1212/NXG.0000000000000010, PubMed 27066539

Publications 2014

Aven T, Pedersen LM (2014)
On how to understand and present the uncertainties in production assurance analyses, with a case study related to a subsea production system
Reliab. Eng. Syst. Saf., 124, 165-170
DOI 10.1016/j.ress.2013.12.003

Publications 2013

Egeland NG, Moen A, Pedersen LM, Brisby H, Gjerstad J (2013)
Spinal nociceptive hyperexcitability induced by experimental disc herniation is associated with enhanced local expression of Csf1 and FasL
Pain, 154 (9), 1743-1748
DOI 10.1016/j.pain.2013.05.034, PubMed 23711477

Jacobsen LM, Schistad EI, Storesund A, Pedersen LM, Espeland A, Rygh LJ, Røe C, Gjerstad J (2013)
The MMP1 rs1799750 2G allele is associated with increased low back pain, sciatica, and disability after lumbar disk herniation
Clin J Pain, 29 (11), 967-71
DOI 10.1097/AJP.0b013e31827df7fd, PubMed 23370084

Publications 2012

Olsen MB, Jacobsen LM, Schistad EI, Pedersen LM, Rygh LJ, Røe C, Gjerstad J (2012)
Pain intensity the first year after lumbar disc herniation is associated with the A118G polymorphism in the opioid receptor mu 1 gene: evidence of a sex and genotype interaction
J Neurosci, 32 (29), 9831-4
DOI 10.1523/JNEUROSCI.1742-12.2012, PubMed 22815498

Publications 2011

Eriksen GS, Jacobsen LM, Mahmood A, Pedersen LM, Gjerstad J (2011)
Inhibition of fatty acid amide hydrolase (FAAH) reduces spinal nociceptive responses and expression of spinal long-term potentiation (LTP)
Brain Res Bull, 87 (2-3), 234-7
DOI 10.1016/j.brainresbull.2011.11.009, PubMed 22133920

Publications 2010

Jacobsen LM, Eriksen GS, Pedersen LM, Gjerstad J (2010)
Catechol-O-methyltransferase (COMT) inhibition reduces spinal nociceptive activity
Neurosci Lett, 473 (3), 212-5
DOI 10.1016/j.neulet.2010.02.049, PubMed 20219633

Publications 2009

Pedersen LM, Jacobsen LM, Mollerup S, Gjerstad J (2009)
Spinal cord long-term potentiation (LTP) is associated with increased dorsal horn gene expression of IL-1beta, GDNF and iNOS
Eur J Pain, 14 (3), 255-60
DOI 10.1016/j.ejpain.2009.05.016, PubMed 19596210

Publications 2005

Gjerstad J, Lien GF, Pedersen LM, Valen EC, Mollerup S (2005)
Changes in gene expression of Zif, c-fos and cyclooxygenase-2 associated with spinal long-term potentiation
Neuroreport, 16 (13), 1477-81
DOI 10.1097/01.wnr.0000177004.19946.12, PubMed 16110275

Pedersen LM, Lien GF, Bollerud I, Gjerstad J (2005)
Induction of long-term potentiation in single nociceptive dorsal horn neurons is blocked by the CaMKII inhibitor AIP
Brain Res, 1041 (1), 66-71
DOI 10.1016/j.brainres.2005.02.004, PubMed 15804501