Lars Christian Haugli Bråten
- PhD student; MD
- +47 22 11 77 94 / 992 99 034
Lars Christian Bråten has a medical degree from University of Dundee in Scotland from 2005. He has been working with internal medicine, with a special interest in infectious diseases, until he started as a PhD-student in 2015.
Lars Christian Bråten is currently doing his PhD on clinical outcomes of the AIM-study (Antibiotics in Modic changes) – a randomized trial testing antibiotic treatment in patients with chronic low back pain and Modic changes. He is also working on the Backtobasic-study – a randomized trial testing TNF-α inhibitors in patients with chronic low back pain and Modic changes.
Main supervisor/Co supervisor: Kjersti Storheim, John-Anker Zwart, Elina Schistad and Jens Ivar Brox.
Methodology and interests
Lars Christian Bråten has a strong interest in clinical trials and back pain research, and is also involved in radiological and biomedical changes in patients with chronic back pain. He also has a special interest in research on microbiota of the gut and the sputum. He is a member of the National research school in population based epidemiology (EPINOR).
Cytokine Patterns as Predictors of Antibiotic Treatment Effect in Chronic Low Back Pain with Modic Changes: Subgroup Analyses of a Randomized Trial (AIM Study)
J Pain Res, 16, 1713-1724
Longitudinal Relationship between Reduced Modic change Edema and Disability and Pain in Patients with Chronic Low Back Pain
Spine (Phila Pa 1976) (in press)
Long-Term Use of Amoxicillin Is Associated with Changes in Gene Expression and DNA Methylation in Patients with Low Back Pain and Modic Changes
Antibiotics (Basel), 12 (7)
Minimal important change was on the lower spectrum of previous estimates and responsiveness was sufficient for core outcomes in chronic low back pain
J Clin Epidemiol, 151, 75-87
Correlation between gene expression and MRI STIR signals in patients with chronic low back pain and Modic changes indicates immune involvement
Sci Rep, 12 (1), 215
Letter to the Editor regarding, "Chronic low back pain, bacterial infection, and treatment with antibiotics"
Spine J, 21 (7), 1229-1230
Macrophage migration inhibitory factor: a potential biomarker for chronic low back pain in patients with Modic changes
RMD Open, 7 (2)
Impact of educational level and employment status on short-term and long-term pain relief from supervised exercise therapy and education: an observational study of 22 588 patients with knee and hip osteoarthritis
BMJ Open, 11 (4), e045156
Clinical effect modifiers of antibiotic treatment in patients with chronic low back pain and Modic changes - secondary analyses of a randomised, placebo-controlled trial (the AIM study)
BMC Musculoskelet Disord, 21 (1), 458
Association of Modic change types and their short tau inversion recovery signals with clinical characteristics- a cross sectional study of chronic low back pain patients in the AIM-study
BMC Musculoskelet Disord, 21 (1), 368
The effect of infliximab in patients with chronic low back pain and Modic changes (the BackToBasic study): study protocol of a randomized, double blind, placebo-controlled, multicenter trial
BMC Musculoskelet Disord, 21 (1), 698
Cost-utility analysis of antibiotic treatment in patients with chronic low back pain and Modic changes: results from a randomised, placebo-controlled trial in Norway (the AIM study)
BMJ Open, 10 (6), e035461
Oedema on STIR modified the effect of amoxicillin as treatment for chronic low back pain with Modic changes-subgroup analysis of a randomized trial
Eur Radiol, 31 (6), 4285-4297
Short tau inversion recovery MRI of Modic changes: a reliability study
Acta Radiol Open, 9 (1), 2058460120902402
Efficacy of antibiotic treatment in patients with chronic low back pain and Modic changes (the AIM study): double blind, randomised, placebo controlled, multicentre trial
BMJ, 367, l5654
[A man in his 30s with fever after a safari in South Africa]
Tidsskr Nor Laegeforen, 136 (4), 328-30