Fridtjof Lund-Johansen
- Group leader; MD PhD
- +47 23073016
MD PhD, Leading a group working on array-based protein analysis. Our goal is to make proteomics simple and accessible. In Microsphere Affinity Proteomics (MAP) biotinylated sample proteins are captured onto bead-based antibody arrays and detected by flow cytometry. MAP has a multiplexing capacity similar to that of mass spectrometry but the throughput is at least two orders of magnitude higher. We are currently developing a multiplexed version of the western blot and complete set of MAP assays to analyze proteins and protein complexes in subcellular compartments. We are also developing a MAP array with thousands of recombinant human proteins. The MAP protein array will be used to test the specificity of antibodies to human proteins and to screen for autoantibodies in serum from patients with auto-immune disease and cancer. To validate MAP, we make extensive use of mass spectrometry. We generate reference data sets that are as lookup tables to identify antibody targets that correspond to specific binding or cross-reactivity, respectively. MAP technology is a game changer in antibody validation and protein detection. Lund-Johansen and co-workers have published work on MAP technology published in Molecular&Cellular Proteomics (2009, 2016), Proteomics (2011), New Biotechnology (2012)and Cytometry (2012). More recently, the group has published new bioinformatics for subcellular proteomics (Nature Methods in press)
Publications 2024
Deficient SARS-CoV-2 hybrid immunity during inflammatory bowel disease
Clin Immunol, 271, 110404 (in press)
DOI 10.1016/j.clim.2024.110404, PubMed 39645159
Vaccine responses and hybrid immunity in people living with HIV after SARS-CoV-2 breakthrough infections
NPJ Vaccines, 9 (1), 185
DOI 10.1038/s41541-024-00972-3, PubMed 39384763
People who use drugs show no increase in pre-existing T-cell cross-reactivity toward SARS-CoV-2 but develop a normal polyfunctional T-cell response after standard mRNA vaccination
Front Immunol, 14, 1235210
DOI 10.3389/fimmu.2023.1235210, PubMed 38299149
Dynamics of SARS-CoV-2 immunity after vaccination and breakthrough infection in rituximab-treated rheumatoid arthritis patients: a prospective cohort study
Front Immunol, 15, 1296273
DOI 10.3389/fimmu.2024.1296273, PubMed 38455062
Predictability of antigen binding based on short motifs in the antibody CDRH3
Brief Bioinform, 25 (6)
DOI 10.1093/bib/bbae537, PubMed 39438077
Type I Interferon Autoantibodies Correlate With Cellular Immune Alterations in Severe COVID-19
J Infect Dis, 230 (2), e318-e326
DOI 10.1093/infdis/jiae036, PubMed 38421006
Characterization of the SARS-CoV-2 antibody landscape in Norway in the late summer of 2022: high seroprevalence in all age groups with patterns of primary Omicron infection in children and hybrid immunity in adults
BMC Infect Dis, 24 (1), 841
DOI 10.1186/s12879-024-09670-w, PubMed 39164637
T cell responses to repeated SARS-CoV-2 vaccination and breakthrough infections in patients on TNF inhibitor treatment: a prospective cohort study
EBioMedicine, 108, 105317
DOI 10.1016/j.ebiom.2024.105317, PubMed 39260039
Seroprevalence of SARS-CoV-2 and humoral immune responses to COVID-19 mRNA vaccines among people who use drugs - in the light of tailored mitigating strategies
Harm Reduct J, 21 (1), 120
DOI 10.1186/s12954-024-01023-9, PubMed 38890611
Publications 2023
Effects of remdesivir in patients hospitalised with COVID-19: a systematic review and individual patient data meta-analysis of randomised controlled trials
Lancet Respir Med, 11 (5), 453-464
DOI 10.1016/S2213-2600(22)00528-8, PubMed 36828006
Robust spike-specific CD4+ and CD8+ T cell responses in SARS-CoV-2 vaccinated hematopoietic cell transplantation recipients: a prospective, cohort study
Front Immunol, 14, 1210899
DOI 10.3389/fimmu.2023.1210899, PubMed 37503339
A systematic safety pipeline for selection of T-cell receptors to enter clinical use
NPJ Vaccines, 8 (1), 126
DOI 10.1038/s41541-023-00713-y, PubMed 37607971
Humoral vaccine response and breakthrough infections in kidney transplant recipients during the COVID-19 pandemic: a nationwide cohort study
EClinicalMedicine, 60, 102035
DOI 10.1016/j.eclinm.2023.102035, PubMed 37362086
Functional SARS-CoV-2 cross-reactive CD4+ T cells established in early childhood decline with age
Proc Natl Acad Sci U S A, 120 (12), e2220320120
DOI 10.1073/pnas.2220320120, PubMed 36917669
Humoral immune response to SARS-CoV-2 vaccination in patients with inflammatory bowel disease on immunosuppressive medication: association to serum drug levels and disease type
Scand J Gastroenterol, 58 (8), 874-882
DOI 10.1080/00365521.2023.2177884, PubMed 36788656
Hybrid and SARS-CoV-2-vaccine immunity in kidney transplant recipients
EBioMedicine, 97, 104833
DOI 10.1016/j.ebiom.2023.104833, PubMed 37844534
A strong case for third-party testing
Elife, 12
DOI 10.7554/eLife.93329, PubMed 37962204
Prevalent and immunodominant CD8 T cell epitopes are conserved in SARS-CoV-2 variants
Cell Rep, 42 (1), 111995
DOI 10.1016/j.celrep.2023.111995, PubMed 36656713
COVID-19 patients treated with convalescent plasma
Tidsskr Nor Laegeforen, 143 (11)
DOI 10.4045/tidsskr.22.0577, PubMed 37589359
Convalescent plasma from Norwegian blood donors to treat COVID-19
Tidsskr Nor Laegeforen, 143 (11)
DOI 10.4045/tidsskr.22.0180, PubMed 37589362
Determinants of humoral and cellular immune responses to three doses of mRNA SARS-CoV-2 vaccines in older adults: a longitudinal cohort study
Lancet Healthy Longev, 4 (5), e188-e199
DOI 10.1016/S2666-7568(23)00055-7, PubMed 37148891
Prevalence and Characteristics Associated With Post-COVID-19 Condition Among Nonhospitalized Adolescents and Young Adults
JAMA Netw Open, 6 (3), e235763
DOI 10.1001/jamanetworkopen.2023.5763, PubMed 36995712
Inflammatory markers and pulmonary function in adolescents and young adults 6 months after mild COVID-19
Front Immunol, 13, 1081718
DOI 10.3389/fimmu.2022.1081718, PubMed 36685555
Author Correction: Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants
NPJ Vaccines, 8 (1), 4
DOI 10.1038/s41541-023-00600-6, PubMed 36697432
Efficacy and safety of baricitinib in hospitalized adults with severe or critical COVID-19 (Bari-SolidAct): a randomised, double-blind, placebo-controlled phase 3 trial
Crit Care, 27 (1), 9
DOI 10.1186/s13054-022-04205-8, PubMed 36627655
T cell responses to SARS-CoV-2 vaccination differ by disease-modifying therapy for multiple sclerosis
JCI Insight, 8 (12)
DOI 10.1172/jci.insight.165111, PubMed 37159281
Humoral Response After 6 or More Successive Doses of SARS-CoV-2 mRNA Vaccines in Kidney Transplant Recipients-Should We Keep Vaccinating?
Transplantation, 107 (10), e279-e280
DOI 10.1097/TP.0000000000004732, PubMed 37496122
Publications 2022
Progress and challenges for the machine learning-based design of fit-for-purpose monoclonal antibodies
MAbs, 14 (1), 2008790
DOI 10.1080/19420862.2021.2008790, PubMed 35293269
In silico proof of principle of machine learning-based antibody design at unconstrained scale
MAbs, 14 (1), 2031482
DOI 10.1080/19420862.2022.2031482, PubMed 35377271
Chasing neoantigens; invite naïve T cells to the party
Curr Opin Immunol, 75, 102172
DOI 10.1016/j.coi.2022.102172, PubMed 35279483
Prevention of covid-19 and other acute respiratory infections with cod liver oil supplementation, a low dose vitamin D supplement: quadruple blinded, randomised placebo controlled trial
BMJ, 378, e071245
DOI 10.1136/bmj-2022-071245, PubMed 36215222
The persistence of anti-Spike antibodies following two SARS-CoV-2 vaccine doses in patients on immunosuppressive therapy compared to healthy controls-a prospective cohort study
BMC Med, 20 (1), 378
DOI 10.1186/s12916-022-02587-8, PubMed 36199139
Target organ expression and biomarker characterization of chemokine CCL21 in systemic sclerosis associated pulmonary arterial hypertension
Front Immunol, 13, 991743
DOI 10.3389/fimmu.2022.991743, PubMed 36211384
Omicron Variant Generates a Higher and More Sustained Viral Load in Nasopharynx and Saliva Than the Delta Variant of SARS-CoV-2
Viruses, 14 (11)
DOI 10.3390/v14112420, PubMed 36366518
Immune responses to SARS-CoV-2 vaccines in celiac disease
Scand J Gastroenterol, 58 (2), 142-147
DOI 10.1080/00365521.2022.2114809, PubMed 36049123
Immune responses in Omicron SARS-CoV-2 breakthrough infection in vaccinated adults
Nat Commun, 13 (1), 4165
DOI 10.1038/s41467-022-31888-y, PubMed 35851055
Immunogenicity and Safety of a Third SARS-CoV-2 Vaccine Dose in Patients With Multiple Sclerosis and Weak Immune Response After COVID-19 Vaccination
JAMA Neurol, 79 (3), 307-309
DOI 10.1001/jamaneurol.2021.5109, PubMed 35072702
EWAS of post-COVID-19 patients shows methylation differences in the immune-response associated gene, IFI44L, three months after COVID-19 infection
Sci Rep, 12 (1), 11478
DOI 10.1038/s41598-022-15467-1, PubMed 35798818
Fourth dose of the SARS-CoV-2 vaccine in kidney transplant recipients with previously impaired humoral antibody response
Am J Transplant, 22 (11), 2704-2706
DOI 10.1111/ajt.17091, PubMed 35533010
Rituximab-treated patients with lymphoma develop strong CD8 T-cell responses following COVID-19 vaccination
Br J Haematol, 197 (6), 697-708
DOI 10.1111/bjh.18149, PubMed 35254660
Unconstrained generation of synthetic antibody-antigen structures to guide machine learning methodology for antibody specificity prediction
Nat Comput Sci, 2 (12), 845-865
DOI 10.1038/s43588-022-00372-4, PubMed 38177393
Immunogenicity and Safety of Standard and Third-Dose SARS-CoV-2 Vaccination in Patients Receiving Immunosuppressive Therapy
Arthritis Rheumatol, 74 (8), 1321-1332
DOI 10.1002/art.42153, PubMed 35507355
Breakthrough infections with the omicron and delta variants of SARS-CoV-2 result in similar re-activation of vaccine-induced immunity
Front Immunol, 13, 964525
DOI 10.3389/fimmu.2022.964525, PubMed 36159859
Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants
NPJ Vaccines, 7 (1), 174
DOI 10.1038/s41541-022-00586-7, PubMed 36585405
Prevalence of antibodies against SARS-CoV-2 in the Norwegian population, August 2021
Influenza Other Respir Viruses, 16 (6), 1004-1013
DOI 10.1111/irv.13024, PubMed 35770841
Publications 2021
A compact vocabulary of paratope-epitope interactions enables predictability of antibody-antigen binding
Cell Rep, 34 (11), 108856
DOI 10.1016/j.celrep.2021.108856, PubMed 33730590
Evaluation of the Effects of Remdesivir and Hydroxychloroquine on Viral Clearance in COVID-19 : A Randomized Trial
Ann Intern Med, 174 (9), 1261-1269
DOI 10.7326/M21-0653, PubMed 34251903
Covid-19 transmission in fitness centers in Norway - a randomized trial
BMC Public Health, 21 (1), 2103
DOI 10.1186/s12889-021-12073-0, PubMed 34789188
Humoral and cellular immune responses to two and three doses of SARS-CoV-2 vaccines in rituximab-treated patients with rheumatoid arthritis: a prospective, cohort study
Lancet Rheumatol, 4 (3), e177-e187
DOI 10.1016/S2665-9913(21)00394-5, PubMed 34977602
Humoral immunity to SARS-CoV-2 mRNA vaccination in multiple sclerosis: the relevance of time since last rituximab infusion and first experience from sporadic revaccinations
J Neurol Neurosurg Psychiatry, 94 (1), 19-22
DOI 10.1136/jnnp-2021-327612, PubMed 34670844
Neutrophil count predicts clinical outcome in hospitalized COVID-19 patients: Results from the NOR-Solidarity trial
J Intern Med, 291 (2), 241-243
DOI 10.1111/joim.13377, PubMed 34411368
Persistent pulmonary pathology after COVID-19 is associated with high viral load, weak antibody response, and high levels of matrix metalloproteinase-9
Sci Rep, 11 (1), 23205
DOI 10.1038/s41598-021-02547-x, PubMed 34853380
Towards reproducibility in large-scale analysis of protein-protein interactions
Nat Methods, 18 (7), 720-721
DOI 10.1038/s41592-021-01202-7, PubMed 34211189
Spatial-proteomics reveals phospho-signaling dynamics at subcellular resolution
Nat Commun, 12 (1), 7113
DOI 10.1038/s41467-021-27398-y, PubMed 34876567
Low Immunization Rate in Kidney Transplant Recipients Also After Dose 2 of the BNT162b2 Vaccine: Continue to Keep Your Guard up!
Transplantation, 105 (8), e80-e81
DOI 10.1097/TP.0000000000003856, PubMed 34132229
Thrombosis and Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination
N Engl J Med, 384 (22), 2124-2130
DOI 10.1056/NEJMoa2104882, PubMed 33835768
Trends in seroprevalence of SARS-CoV-2 and infection fatality rate in the Norwegian population through the first year of the COVID-19 pandemic
Influenza Other Respir Viruses, 16 (2), 204-212
DOI 10.1111/irv.12932, PubMed 34751488
Publications 2020
Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients
Proc Natl Acad Sci U S A, 117 (40), 25018-25025
DOI 10.1073/pnas.2010540117, PubMed 32943538
The Antibody Society's antibody validation webinar series
MAbs, 12 (1), 1794421
DOI 10.1080/19420862.2020.1794421, PubMed 32748696
Publications 2019
Finding Neo (antigens, that is)
Blood, 134 (2), 108-109
DOI 10.1182/blood.2019001334, PubMed 31296544
Publications 2018
High-resolution antibody array analysis of proteins from primary human keratinocytes and leukocytes
PLoS One, 13 (12), e0209271
DOI 10.1371/journal.pone.0209271, PubMed 30589857
A high-throughput pipeline for validation of antibodies
Nat Methods, 15 (11), 909-912
DOI 10.1038/s41592-018-0179-8, PubMed 30377371
Publications 2017
Should we ignore western blots when selecting antibodies for other applications?
Nat Methods, 14 (3), 215
DOI 10.1038/nmeth.4192, PubMed 28245212
Novel serum and bile protein markers predict primary sclerosing cholangitis disease severity and prognosis
J Hepatol, 66 (6), 1214-1222
DOI 10.1016/j.jhep.2017.01.019, PubMed 28161472
Publications 2016
[Letter to the Editor] The need for improved education and training in research antibody usage and validation practices
Biotechniques, 61 (1), 16-8
DOI 10.2144/000114431, PubMed 27401669
High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells
Mol Cell Proteomics, 15 (4), 1246-61
DOI 10.1074/mcp.M115.054593, PubMed 26785729
MetaMass, a tool for meta-analysis of subcellular proteomics data
Nat Methods, 13 (10), 837-40
DOI 10.1038/nmeth.3967, PubMed 27571551
Antibody Engineering & Therapeutics, the annual meeting of The Antibody Society December 7-10, 2015, San Diego, CA, USA
MAbs, 8 (3), 617-52
DOI 10.1080/19420862.2016.1153211, PubMed 26909869
Targeting of cancer neoantigens with donor-derived T cell receptor repertoires
Science, 352 (6291), 1337-41
DOI 10.1126/science.aaf2288, PubMed 27198675
Publications 2015
Recombinant renewable polyclonal antibodies
MAbs, 7 (1), 32-41
DOI 10.4161/19420862.2015.989047, PubMed 25530082
Enhanced liver fibrosis score predicts transplant-free survival in primary sclerosing cholangitis
Hepatology, 62 (1), 188-97
DOI 10.1002/hep.27825, PubMed 25833813
Publications 2014
Antibody engineering and therapeutics, The Annual Meeting of the Antibody Society: December 8-12, 2013, Huntington Beach, CA
MAbs, 6 (3), 577-618
DOI 10.4161/mabs.28421, PubMed 24589717
Publications 2013
Alloreactive cytotoxic T cells provide means to decipher the immunopeptidome and reveal a plethora of tumor-associated self-epitopes
Proc Natl Acad Sci U S A, 111 (1), 403-8
DOI 10.1073/pnas.1306549111, PubMed 24344295
Publications 2011
Antibody array analysis of labelled proteomes: how should we control specificity?
N Biotechnol, 29 (5), 578-85
DOI 10.1016/j.nbt.2011.07.008, PubMed 21840428
Multiplexed immuno-precipitation with 1725 commercially available antibodies to cellular proteins
Proteomics, 11 (23), 4578-82
DOI 10.1002/pmic.201000744, PubMed 21956872
An automated analysis of highly complex flow cytometry-based proteomic data
Cytometry A, 81 (2), 120-9
DOI 10.1002/cyto.a.22011, PubMed 22213549
Publications 2010
Targeting B cell leukemia with highly specific allogeneic T cells with a public recognition motif
Leukemia, 24 (11), 1901-9
DOI 10.1038/leu.2010.186, PubMed 20844564
Rapid generation of rotavirus-specific human monoclonal antibodies from small-intestinal mucosa
J Immunol, 185 (9), 5377-83
DOI 10.4049/jimmunol.1001587, PubMed 20935207
Publications 2009
Dendritic cells engineered to express defined allo-HLA peptide complexes induce antigen-specific cytotoxic T cells efficiently killing tumour cells
Scand J Immunol, 69 (4), 319-28
DOI 10.1111/j.1365-3083.2008.02223.x, PubMed 19284496
Publications 2008
The monoclonal antibody 6B9 recognizes CD44 and not cell surface transglutaminase 2
Scand J Immunol, 68 (5), 534-42
DOI 10.1111/j.1365-3083.2008.02173.x, PubMed 18803608
Antibody array analysis with label-based detection and resolution of protein size
Mol Cell Proteomics, 8 (2), 245-57
DOI 10.1074/mcp.M800171-MCP200, PubMed 18796702
Publications 2007
High expression of CD7 on CD34+ cells is not linked to deletion of derivative chromosome 9 or lack of dendritic cells in chronic myeloid leukaemia
Scand J Clin Lab Invest, 68 (2), 93-8
DOI 10.1080/00365510701558477, PubMed 17852828
Assay for monitoring in vitro selective depletion strategies in allogeneic stem cell transplantation
Cytotherapy, 9 (6), 600-10
DOI 10.1080/14653240701510573, PubMed 17882725
Publications 2006
Plasmacytoid dendritic cells induce a distinct cytokine pattern in virus-specific CD4+ memory T cells that is modulated by CpG oligodeoxynucleotides
Scand J Immunol, 64 (4), 404-11
DOI 10.1111/j.1365-3083.2006.01792.x, PubMed 16970682
Plasmacytoid DCs regulate recall responses by rapid induction of IL-10 in memory T cells
Blood, 109 (8), 3369-76
DOI 10.1182/blood-2006-06-031484, PubMed 17158235
Signaling through toll-like receptor 7/8 induces the differentiation of human bone marrow CD34+ progenitor cells along the myeloid lineage
J Mol Biol, 364 (5), 945-54
DOI 10.1016/j.jmb.2006.09.054, PubMed 17049554
Publications 2005
CD11c+ dendritic cells and plasmacytoid DCs are activated by human cytomegalovirus and retain efficient T cell-stimulatory capability upon infection
Blood, 107 (5), 2022-9
DOI 10.1182/blood-2005-05-2016, PubMed 16269620
Publications 2004
Plasmacytoid dendritic cells activate allergen-specific TH2 memory cells: modulation by CpG oligodeoxynucleotides
J Allergy Clin Immunol, 114 (2), 436-43
DOI 10.1016/j.jaci.2004.04.035, PubMed 15316529
Publications 2003
Epidermal growth factor receptor inhibition induces trichomegaly
Acta Oncol, 42 (4), 345-6
DOI 10.1080/02841860310006038, PubMed 12899508
Publications 2002
Involvement of plasmacytoid dendritic cells in human diseases
Hum Immunol, 63 (12), 1201-5
DOI 10.1016/s0198-8859(02)00759-0, PubMed 12480264
Publications 2001
Plasmacytoid dendritic cells (natural interferon- alpha/beta-producing cells) accumulate in cutaneous lupus erythematosus lesions
Am J Pathol, 159 (1), 237-43
DOI 10.1016/s0002-9440(10)61689-6, PubMed 11438470
Publications 2000
Experimentally induced recruitment of plasmacytoid (CD123high) dendritic cells in human nasal allergy
J Immunol, 165 (7), 4062-8
DOI 10.4049/jimmunol.165.7.4062, PubMed 11034417
Flow cytometric analysis of immunoprecipitates: high-throughput analysis of protein phosphorylation and protein-protein interactions
Cytometry, 39 (4), 250-9
DOI 10.1002/(sici)1097-0320(20000401)39:4<250::aid-cyto2>3.0.co;2-s, PubMed 10738277
Publications 1999
Primitive human hematopoietic progenitor cells express receptors for granulocyte-macrophage colony-stimulating factor
Exp Hematol, 27 (4), 762-72
DOI 10.1016/s0301-472x(98)00081-2, PubMed 10210334
[Dendritic cells--strong candidates for immunotherapy]
Tidsskr Nor Laegeforen, 119 (17), 2510-4
PubMed 10425906
Publications 1998
Transgene expression of bcl-xL permits anti-immunoglobulin (Ig)-induced proliferation in xid B cells
J Exp Med, 187 (7), 1081-91
DOI 10.1084/jem.187.7.1081, PubMed 9529324
Publications 1997
Dendritic cell ontogeny: a human dendritic cell lineage of myeloid origin
Proc Natl Acad Sci U S A, 94 (23), 12551-6
DOI 10.1073/pnas.94.23.12551, PubMed 9356487
Publications 1996
Apoptosis in hematopoietic cells is associated with an extensive decrease in cellular phosphotyrosine content that can be inhibited by the tyrosine phosphatase antagonist pervanadate
Cytometry, 25 (2), 182-90
DOI 10.1002/(SICI)1097-0320(19961001)25:2<182::AID-CYTO7>3.0.CO;2-J, PubMed 8891448
Expression and function of receptors for stem cell factor and erythropoietin during lineage commitment of human hematopoietic progenitor cells
Blood, 88 (5), 1594-607
PubMed 8781415
Granulocytic and monocytic differentiation of CD34hi cells is associated with distinct changes in the expression of the PU.1-regulated molecules, CD64 and macrophage colony-stimulating factor receptor
Blood, 88 (10), 3741-54
PubMed 8916938
Publications 1995
Flow cytometric assessment of peripheral blood contamination and proliferative activity of human bone marrow cell populations
Cytometry, 19 (1), 77-85
DOI 10.1002/cyto.990190110, PubMed 7705188
Expression of leukocyte differentiation antigens during the differentiation of HL-60 cells induced by 1,25-dihydroxyvitamin D3: comparison with the maturation of normal monocytic and granulocytic bone marrow cells
J Leukoc Biol, 58 (5), 547-55
DOI 10.1002/jlb.58.5.547, PubMed 7595056
Expression of cell surface antigens during the differentiation of HL-60 cells induced by 1,25-dihydroxyvitamin D3, retinoic acid and DMSO
Leuk Res, 19 (1), 57-64
DOI 10.1016/0145-2126(94)00061-e, PubMed 7837818
CD64/Fc gamma RI is a granulo-monocytic lineage marker on CD34+ hematopoietic progenitor cells
Blood, 85 (9), 2402-13
PubMed 7537112
The "common stem cell" hypothesis reevaluated: human fetal bone marrow contains separate populations of hematopoietic and stromal progenitors
Blood, 85 (9), 2422-35
PubMed 7537114
Publications 1994
Expression of cell surface markers during differentiation of CD34+, CD38-/lo fetal and adult bone marrow cells
Immunomethods, 5 (3), 179-88
DOI 10.1006/immu.1994.1054, PubMed 7540098
Commentary: hematopoietic progenitors in fetal and adult tissue
Blood Cells, 20 (2-3), 392-6
PubMed 7538344
Publications 1993
Expression and functions of membrane molecules on human monocytes and granulocytes
The Gade Institute, Department of Pathology, University of Bergen, Bergen, 1 b. (flere pag.)
BIBSYS 940856409, ISBN 82-91304-03-3
Use of monoclonal antibodies to study hematopoietic cell function
J Hematother, 2 (3), 395-412
DOI 10.1089/scd.1.1993.2.395, PubMed 7922002
Activation of human monocytes and granulocytes by monoclonal antibodies to glycosylphosphatidylinositol-anchored antigens
Eur J Immunol, 23 (11), 2782-91
DOI 10.1002/eji.1830231110, PubMed 8223854
Differential surface expression of cell adhesion molecules during granulocyte maturation
J Leukoc Biol, 54 (1), 47-55
DOI 10.1002/jlb.54.1.47, PubMed 7687642
CD53, a protein with four membrane-spanning domains, mediates signal transduction in human monocytes and B cells
J Immunol, 151 (2), 707-16
PubMed 8335905
Assessment of hematopoietic cell differentiation by multidimensional flow cytometry
J Hematother, 2 (3), 431-47
DOI 10.1089/scd.1.1993.2.431, PubMed 7522894
Publications 1992
Signal transduction in monocytes and granulocytes measured by multiparameter flow cytometry
Cytometry, 13 (7), 693-702
DOI 10.1002/cyto.990130705, PubMed 1451600
Activation of human phagocytes through carbohydrate antigens (CD15, sialyl-CD15, CDw17, and CDw65)
J Immunol, 148 (10), 3221-9
PubMed 1349618
Publications 1991
Negative selection of human monocytes using magnetic particles covered by anti-lymphocyte antibodies
J Immunol Methods, 137 (1), 89-94
DOI 10.1016/0022-1759(91)90397-x, PubMed 2010620
The IgG FcRII and the PI-linked IgG FcRIII trigger cytoplasmic calcium fluxes independently in human granulocytes
Scand J Immunol, 33 (3), 261-6
DOI 10.1111/j.1365-3083.1991.tb01771.x, PubMed 1826373
Publications 1990
Flow cytometric assay for the measurement of human bone marrow phenotype, function and cell cycle
Cytometry, 11 (5), 610-6
DOI 10.1002/cyto.990110508, PubMed 2379452
Signal transduction in human monocytes and granulocytes through the PI-linked antigen CD14
FEBS Lett, 273 (1-2), 55-8
DOI 10.1016/0014-5793(90)81049-t, PubMed 1699812