Martin Prøven Bogsrud
- PhD, MD
- +47 230 75614
Publications 2024
The singular French PCSK9-p.Ser127Arg gain-of-function variant: A significant player in cholesterol levels from a 775-year-old common ancestor
Atherosclerosis, 399, 118596
DOI 10.1016/j.atherosclerosis.2024.118596, PubMed 39500114
Correction to: Real-World Outcomes with Lomitapide Use in Paediatric Patients with Homozygous Familial Hypercholesterolaemia
Adv Ther, 41 (4), 1765-1769
DOI 10.1007/s12325-023-02739-z, PubMed 38376744
Flavonoids regulate LDLR through different mechanisms tied to their specific structures
J Lipid Res, 65 (5), 100539
DOI 10.1016/j.jlr.2024.100539, PubMed 38556050
Plasma legumain in familial hypercholesterolemia: associations with statin use and cardiovascular risk markers
Scand J Clin Lab Invest, 84 (1), 24-29
DOI 10.1080/00365513.2024.2309617, PubMed 38319290
Lipoprotein(a) in children and adolescents with genetically confirmed familial hypercholesterolemia followed up at a specialized lipid clinic
Atheroscler Plus, 57, 13-18
DOI 10.1016/j.athplu.2024.06.002, PubMed 39027312
Adherence to the Healthy Nordic Food Index is associated with reduced plasma levels of inflammatory markers in patients with heterozygous familial hypercholesterolemia
Atheroscler Plus, 58, 38-45
DOI 10.1016/j.athplu.2024.10.003, PubMed 39525275
Gene expression profiling in elderly patients with familial hypercholesterolemia with and without coronary heart disease
Atherosclerosis, 392, 117507
DOI 10.1016/j.atherosclerosis.2024.117507, PubMed 38663317
Molecular genetics in 1991 arrhythmia probands and 2782 relatives in Norway: Results from 17 years of genetic testing in a national laboratory
Clin Genet, 106 (5), 585-602
DOI 10.1111/cge.14593, PubMed 39073097
Publications 2023
Dietary fat quality, plasma atherogenic lipoproteins, and atherosclerotic cardiovascular disease: An overview of the rationale for dietary recommendations for fat intake
Atherosclerosis, 389, 117433
DOI 10.1016/j.atherosclerosis.2023.117433, PubMed 38219649
Young women with familial hypercholesterolemia have higher LDL-cholesterol burden than men: Novel data using repeated measurements during 12-years follow-up
Atheroscler Plus, 51, 28-34
DOI 10.1016/j.athplu.2023.01.001, PubMed 36911286
Association between Nordic and Mediterranean diets with lipoprotein phenotype assessed by 1HNMR in children with familial hypercholesterolemia
Atherosclerosis, 373, 38-45
DOI 10.1016/j.atherosclerosis.2023.04.009, PubMed 37137225
Disease progression rate is a strong predictor of ventricular arrhythmias in patients with cardiac laminopathies: a primary prevention cohort study
Europace, 25 (2), 634-642
DOI 10.1093/europace/euac192, PubMed 36352512
LDL cholesterol targets rarely achieved in familial hypercholesterolemia patients: A sex and gender-specific analysis
Atherosclerosis, 384, 117117
DOI 10.1016/j.atherosclerosis.2023.03.022, PubMed 37080805
Missense mutation Q384K in the APOB gene affecting the large lipid transfer module of apoB reduces the secretion of apoB-100 in the liver without reducing the secretion of apoB-48 in the intestine
J Clin Lipidol, 17 (6), 800-807
DOI 10.1016/j.jacl.2023.08.009, PubMed 37718180
Molecular genetic testing and measurement of levels of GPIHBP1 autoantibodies in patients with severe hypertriglyceridemia: The importance of identifying the underlying cause of hypertriglyceridemia
J Clin Lipidol, 18 (1), e80-e89
DOI 10.1016/j.jacl.2023.11.002, PubMed 37981531
[Correction: High levels of lipoprotein(a) – assessment and treatment]
Tidsskr Nor Laegeforen, 143 (2)
DOI 10.4045/tidsskr.23.0023, PubMed 36718898
Functional characterization of missense variants affecting the extracellular domains of ABCA1 using a fluorescence-based assay
J Lipid Res, 65 (1), 100482
DOI 10.1016/j.jlr.2023.100482, PubMed 38052254
Maternal prenatal cholesterol levels predict offspring weight trajectories during childhood in the Norwegian Mother, Father and Child Cohort Study
BMC Med, 21 (1), 43
DOI 10.1186/s12916-023-02742-9, PubMed 36747215
Publications 2022
Differential effects of bariatric surgery and lifestyle interventions on plasma levels of Lp(a) and fatty acids
Lipids Health Dis, 21 (1), 145
DOI 10.1186/s12944-022-01756-1, PubMed 36577984
Use of statins and other lipid-modifying agents across pregnancy: A nationwide drug utilization study in Norway in 2005-2018
Atherosclerosis, 368, 25-34
DOI 10.1016/j.atherosclerosis.2022.11.022, PubMed 36522216
The risk of various types of cardiovascular diseases in mutation positive familial hypercholesterolemia; a review
Front Genet, 13, 1072108
DOI 10.3389/fgene.2022.1072108, PubMed 36561318
Treatment goals in familial hypercholesterolaemia-time to consider low-density lipoprotein-cholesterol burden
Eur J Prev Cardiol, 29 (17), 2278-2280
DOI 10.1093/eurjpc/zwab228, PubMed 34935933
Cascade screening for familial hypercholesterolemia should be organized at a national level
Curr Opin Lipidol, 33 (4), 231-236
DOI 10.1097/MOL.0000000000000832, PubMed 35942821
What characterizes event-free elderly FH patients? A comprehensive lipoprotein profiling
Nutr Metab Cardiovasc Dis, 32 (7), 1651-1660
DOI 10.1016/j.numecd.2022.03.028, PubMed 35527125
Increased risk of peripheral artery disease in persons with familial hypercholesterolaemia: a prospective registry study
Eur J Prev Cardiol, 28 (18), e11-e13
DOI 10.1093/eurjpc/zwaa024, PubMed 33623989
Timing of cardioverter-defibrillator implantation in patients with cardiac laminopathies-External validation of the LMNA-risk ventricular tachyarrhythmia calculator
Heart Rhythm, 20 (3), 423-429
DOI 10.1016/j.hrthm.2022.11.024, PubMed 36494026
Highly malignant disease in childhood-onset arrhythmogenic right ventricular cardiomyopathy
Eur Heart J, 43 (45), 4694-4703
DOI 10.1093/eurheartj/ehac485, PubMed 36036653
Molecular genetics in 4408 cardiomyopathy probands and 3008 relatives in Norway: 17 years of genetic testing in a national laboratory
Eur J Prev Cardiol, 29 (13), 1789-1799
DOI 10.1093/eurjpc/zwac102, PubMed 35653365
Risk of stroke in genetically verified familial hypercholesterolemia: A prospective matched cohort study
Atherosclerosis, 358, 34-40
DOI 10.1016/j.atherosclerosis.2022.08.015, PubMed 36084445
High levels of lipoprotein(a) - assessment and treatment
Tidsskr Nor Laegeforen, 142 (1)
DOI 10.4045/tidsskr.21.0800, PubMed 36655975
Publications 2021
Children with familial hypercholesterolemia display changes in LDL and HDL function: A cross-sectional study
J Intern Med, 290 (5), 1083-1097
DOI 10.1111/joim.13383, PubMed 34506681
Comparison of the mutation spectrum and association with pre and post treatment lipid measures of children with heterozygous familial hypercholesterolaemia (FH) from eight European countries
Atherosclerosis, 319, 108-117
DOI 10.1016/j.atherosclerosis.2021.01.008, PubMed 33508743
Long term follow-up of children with familial hypercholesterolemia and relatively normal LDL-cholesterol at diagnosis
J Clin Lipidol, 15 (2), 375-378
DOI 10.1016/j.jacl.2021.01.007, PubMed 33608220
Loss of statin treatment years during pregnancy and breastfeeding periods in women with familial hypercholesterolemia
Atherosclerosis, 335, 8-15
DOI 10.1016/j.atherosclerosis.2021.09.003, PubMed 34520888
Thirty percent of children and young adults with familial hypercholesterolemia treated with statins have adherence issues
Am J Prev Cardiol, 6, 100180
DOI 10.1016/j.ajpc.2021.100180, PubMed 34327501
Molecular genetic testing for autosomal dominant hypercholesterolemia in 29,449 Norwegian index patients and 14,230 relatives during the years 1993-2020
Atherosclerosis, 322, 61-66
DOI 10.1016/j.atherosclerosis.2021.02.022, PubMed 33740630
The importance of cascade genetic screening for diagnosing autosomal dominant hypercholesterolemia: Results from twenty years of a national screening program in Norway
J Clin Lipidol, 15 (5), 674-681
DOI 10.1016/j.jacl.2021.08.007, PubMed 34479846
Left Ventricular Dysfunction in Arrhythmogenic Cardiomyopathy: Association With Exercise Exposure, Genetic Basis, and Prognosis
J Am Heart Assoc, 10 (8), e018680
DOI 10.1161/JAHA.120.018680, PubMed 33821670
Dietary intake and lipid levels in Norwegian and Spanish children with familial hypercholesterolemia
Nutr Metab Cardiovasc Dis, 31 (4), 1299-1307
DOI 10.1016/j.numecd.2020.12.002, PubMed 33549456
Sex differences in disease progression and arrhythmic risk in patients with arrhythmogenic cardiomyopathy
Europace, 23 (7), 1084-1091
DOI 10.1093/europace/euab077, PubMed 33829244
Gender differences in nutrition literacy levels among university students and employees: a descriptive study
J Nutr Sci, 10, e56
DOI 10.1017/jns.2021.47, PubMed 34367630
Novel associations between parental and newborn cord blood metabolic profiles in the Norwegian Mother, Father and Child Cohort Study
BMC Med, 19 (1), 91
DOI 10.1186/s12916-021-01959-w, PubMed 33849542
Cholesterol at ages 6, 12 and 24 months: Tracking and associations with diet and maternal cholesterol in the Infant Cholesterol Study
Atherosclerosis, 326, 11-16
DOI 10.1016/j.atherosclerosis.2021.04.017, PubMed 33990045
Publications 2020
Prevalence of genetically verified familial hypercholesterolemia among young (<45 years) Norwegian patients hospitalized with acute myocardial infarction
J Clin Lipidol, 14 (3), 339-345
DOI 10.1016/j.jacl.2020.04.002, PubMed 32418822
Subjects with familial hypercholesterolemia have lower aortic valve area and higher levels of inflammatory biomarkers
J Clin Lipidol, 15 (1), 134-141
DOI 10.1016/j.jacl.2020.12.006, PubMed 33358307
Reducing the Clinical and Public Health Burden of Familial Hypercholesterolemia: A Global Call to Action
JAMA Cardiol, 5 (2), 217-229
DOI 10.1001/jamacardio.2019.5173, PubMed 31895433
2.5-fold increased risk of recurrent acute myocardial infarction with familial hypercholesterolemia
Atherosclerosis, 319, 28-34
DOI 10.1016/j.atherosclerosis.2020.12.019, PubMed 33465659
Genetic testing is essential for initiating statin therapy in children with familial hypercholesterolemia: Examples from Scandinavia
Atherosclerosis, 316, 48-52
DOI 10.1016/j.atherosclerosis.2020.11.027, PubMed 33302044
Publications 2019
Real-World Outcomes with Lomitapide Use in Paediatric Patients with Homozygous Familial Hypercholesterolaemia
Adv Ther, 36 (7), 1786-1811
DOI 10.1007/s12325-019-00985-8, PubMed 31102204
LDL-cholesterol goal achievement, cardiovascular disease, and attributed risk of Lp(a) in a large cohort of predominantly genetically verified familial hypercholesterolemia
J Clin Lipidol, 13 (2), 279-286
DOI 10.1016/j.jacl.2019.01.010, PubMed 30910667
Editorial Comment: Hyperlipidaemia and cardiovascular disease and impact of early cholesterol accumulation
Curr Opin Lipidol, 30 (6), 490-493
DOI 10.1097/MOL.0000000000000646, PubMed 31688171
Lower risk of smoking-related cancer in individuals with familial hypercholesterolemia compared with controls: a prospective matched cohort study
Sci Rep, 9 (1), 19273
DOI 10.1038/s41598-019-55682-x, PubMed 31848411
Association of Low-Density Lipoprotein Cholesterol With Risk of Aortic Valve Stenosis in Familial Hypercholesterolemia
JAMA Cardiol, 4 (11), 1156-1159
DOI 10.1001/jamacardio.2019.3903, PubMed 31617858
Lipoprotein(a) concentration is associated with plasma arachidonic acid in subjects with familial hypercholesterolaemia
Br J Nutr, 122 (7), 790-799
DOI 10.1017/S0007114519001600, PubMed 31262370
Profiling of immune-related gene expression in children with familial hypercholesterolaemia
J Intern Med, 287 (3), 310-321
DOI 10.1111/joim.13001, PubMed 31631426
Comparison of the characteristics at diagnosis and treatment of children with heterozygous familial hypercholesterolaemia (FH) from eight European countries
Atherosclerosis, 292, 178-187
DOI 10.1016/j.atherosclerosis.2019.11.012, PubMed 31809987
Infant cholesterol and glycated haemoglobin concentrations vary widely-Associations with breastfeeding, infant diet and maternal biomarkers
Acta Paediatr, 109 (1), 115-121
DOI 10.1111/apa.14936, PubMed 31299108
Postprandial changes in gene expression of cholesterol influx and efflux mediators after intake of SFA compared with n-6 PUFA in subjects with and without familial hypercholesterolaemia: secondary outcomes of a randomised controlled trial
J Nutr Sci, 8, e27
DOI 10.1017/jns.2019.25, PubMed 31448116
Publications 2018
Overview of the current status of familial hypercholesterolaemia care in over 60 countries - The EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)
Atherosclerosis, 277, 234-255
DOI 10.1016/j.atherosclerosis.2018.08.051, PubMed 30270054
Sex differences in cholesterol levels from birth to 19 years of age may lead to increased cholesterol burden in females with FH
J Clin Lipidol, 12 (3), 748-755.e2
DOI 10.1016/j.jacl.2018.02.021, PubMed 29609857
Risk of Ischemic Stroke and Total Cerebrovascular Disease in Familial Hypercholesterolemia: A Register Study From Norway
Stroke, 50 (1), 172-174
DOI 10.1161/STROKEAHA.118.023456, PubMed 30580708
Some children with a familial hypercholesterolemia mutation may exhibit persistent low LDL levels
J Clin Lipidol, 12 (5), 1327-1328
DOI 10.1016/j.jacl.2018.06.012, PubMed 30033003
Delayed postprandial TAG peak after intake of SFA compared with PUFA in subjects with and without familial hypercholesterolaemia: a randomised controlled trial
Br J Nutr, 119 (10), 1142-1150
DOI 10.1017/S0007114518000673, PubMed 29759104
Delayed postprandial TAG peak after intake of SFA compared with PUFA in subjects with and without familial hypercholesterolaemia: a randomised controlled trial
Br J Nutr, 120 (5), 597
DOI 10.1017/S0007114518001769, PubMed 30047345
Publications 2017
A physically fit woman in her thirties with exertional dyspnoea
Tidsskr Nor Laegeforen, 137 (6), 456-458
DOI 10.4045/tidsskr.16.0538, PubMed 28332800
Treatment goal attainment in children with familial hypercholesterolemia: A cohort study of 302 children in Norway
J Clin Lipidol, 12 (2), 375-382
DOI 10.1016/j.jacl.2017.11.009, PubMed 29310990
Comprehensive lipid and metabolite profiling of children with and without familial hypercholesterolemia: A cross-sectional study
Atherosclerosis, 266, 48-57
DOI 10.1016/j.atherosclerosis.2017.09.021, PubMed 28963918
Hyperlipidemia and cardiovascular disease with focus on familial hypercholesterolemia
Curr Opin Lipidol, 28 (5), 445-447
DOI 10.1097/MOL.0000000000000449, PubMed 28857860
Increased risk of heart failure and atrial fibrillation in heterozygous familial hypercholesterolemia
Atherosclerosis, 266, 69-73
DOI 10.1016/j.atherosclerosis.2017.09.027, PubMed 28992466
Publications 2016
Does intrauterine exposure to hypercholesterolemia adversely affect familial hypercholesterolemia phenotype?
Curr Opin Lipidol, 27 (4), 382-7
DOI 10.1097/MOL.0000000000000299, PubMed 27070077
Data on circulating leukocyte subpopulations and inflammatory proteins in children with familial hypercholesterolemia and healthy children
Data Brief, 10, 587-592
DOI 10.1016/j.dib.2016.12.042, PubMed 28070551
Altered leukocyte distribution under hypercholesterolemia: A cross-sectional study in children with familial hypercholesterolemia
Atherosclerosis, 256, 67-74
DOI 10.1016/j.atherosclerosis.2016.11.031, PubMed 28024183
Pooling and expanding registries of familial hypercholesterolaemia to assess gaps in care and improve disease management and outcomes: Rationale and design of the global EAS Familial Hypercholesterolaemia Studies Collaboration
Atheroscler Suppl, 22, 1-32
DOI 10.1016/j.atherosclerosissup.2016.10.001, PubMed 27939304
Publications 2015
Long-term follow-up of young adults with familial hypercholesterolemia after participation in clinical trials during childhood
J Clin Lipidol, 9 (6), 778-785
DOI 10.1016/j.jacl.2015.08.008, PubMed 26687698
Familial hypercholesterolaemia: A global call to arms
Atherosclerosis, 243 (1), 257-9
DOI 10.1016/j.atherosclerosis.2015.09.021, PubMed 26408930
Publications 2013
[Lipid profile of healthy persons with low-carbohydrate diet]
Tidsskr Nor Laegeforen, 133 (11), 1193-6
DOI 10.4045/tidsskr.12.0034, PubMed 23759780
[M. Baumann and colleagues replies]
Tidsskr Nor Laegeforen, 133 (16), 1685-6
DOI 10.4045/tidsskr.13.1023, PubMed 24005696
No effect of combined coenzyme Q10 and selenium supplementation on atorvastatin-induced myopathy
Scand Cardiovasc J, 47 (2), 80-7
DOI 10.3109/14017431.2012.756119, PubMed 23301875
[Treatment with statins]
Tidsskr Nor Laegeforen, 133 (12-13), 1316-9
DOI 10.4045/tidsskr.12.0825, PubMed 23817262
UGT1A1*28 is associated with decreased systemic exposure of atorvastatin lactone
Mol Diagn Ther, 17 (4), 233-7
DOI 10.1007/s40291-013-0031-x, PubMed 23580084
Publications 2012
Serum levels of proprotein convertase subtilisin/kexin type 9 in subjects with familial hypercholesterolemia indicate that proprotein convertase subtilisin/kexin type 9 is cleared from plasma by low-density lipoprotein receptor-independent pathways
Transl Res, 160 (2), 125-30
DOI 10.1016/j.trsl.2012.01.010, PubMed 22683370
Apheresis in homozygous familial hypercholesterolemia: the results of a follow-up of all Norwegian patients with homozygous familial hypercholesterolemia
J Clin Lipidol, 6 (4), 331-9
DOI 10.1016/j.jacl.2012.03.004, PubMed 22836070
LDL-apheresis affects markers of endothelial function in patients with homozygous familial hypercholesterolemia
Thromb Res, 130 (5), 823-5
DOI 10.1016/j.thromres.2012.06.004, PubMed 22728023
Cholesterol efflux mediators in homozygous familial hypercholesterolemia patients on low-density lipoprotein apheresis
J Clin Lipidol, 7 (2), 109-16
DOI 10.1016/j.jacl.2012.08.001, PubMed 23415429
Elevated serum MMP-9/TIMP-1 ratio in patients with homozygous familial hypercholesterolemia: effects of LDL-apheresis
Cytokine, 61 (1), 194-8
DOI 10.1016/j.cyto.2012.09.016, PubMed 23131422
Publications 2011
Atorvastatin metabolite measurements as a diagnostic tool for statin-induced myopathy
Mol Diagn Ther, 15 (4), 221-7
DOI 10.1007/BF03256413, PubMed 21815705
Publications 2010
HypoCol (red yeast rice) lowers plasma cholesterol - a randomized placebo controlled study
Scand Cardiovasc J, 44 (4), 197-200
DOI 10.3109/14017431003624123, PubMed 20636227
Analysis of LDLR mRNA in patients with familial hypercholesterolemia revealed a novel mutation in intron 14, which activates a cryptic splice site
J Hum Genet, 55 (10), 676-80
DOI 10.1038/jhg.2010.87, PubMed 20703241
Publications 2007
[Practical advice for registration of clinical trials]
Tidsskr Nor Laegeforen, 127 (12), 1654-6
PubMed 17571106
Publications 2006
Exposure of atorvastatin is unchanged but lactone and acid metabolites are increased several-fold in patients with atorvastatin-induced myopathy
Clin Pharmacol Ther, 79 (6), 532-9
DOI 10.1016/j.clpt.2006.02.014, PubMed 16765141