Publications 2021

Futema M, Ramaswami U, Tichy L, Bogsrud MP, Holven KB, Roeters van Lennep J, Wiegman A, Descamps OS, De Leener A, Fastre E, Vrablik M, Freiberger T, Esterbauer H, Dieplinger H, Greber-Platzer S, Medeiros AM, Bourbon M, Mollaki V, Drogari E, Humphries SE (2021)
Comparison of the mutation spectrum and association with pre and post treatment lipid measures of children with heterozygous familial hypercholesterolaemia (FH) from eight European countries
Atherosclerosis, 319, 108-117
DOI 10.1016/j.atherosclerosis.2021.01.008, PubMed 33508743

Johansen AK, Bogsrud MP, Roeters van Lennep J, Narverud I, Langslet G, Retterstøl K, Holven KB (2021)
Long term follow-up of children with familial hypercholesterolemia and relatively normal LDL-cholesterol at diagnosis
J Clin Lipidol (in press)
DOI 10.1016/j.jacl.2021.01.007, PubMed 33608220

Leren TP, Bogsrud MP (2021)
Molecular genetic testing for autosomal dominant hypercholesterolemia in 29,449 Norwegian index patients and 14,230 relatives during the years 1993-2020
Atherosclerosis, 322, 61-66
DOI 10.1016/j.atherosclerosis.2021.02.022, PubMed 33740630

Lie ØH, Chivulescu M, Rootwelt-Norberg C, Ribe M, Bogsrud MP, Lyseggen E, Beitnes JO, Almaas V, Haugaa KH (2021)
Left Ventricular Dysfunction in Arrhythmogenic Cardiomyopathy: Association With Exercise Exposure, Genetic Basis, and Prognosis
J Am Heart Assoc, e018680 (in press)
DOI 10.1161/JAHA.120.018680, PubMed 33821670

Øyri LKL, Bogsrud MP, Christensen JJ, Ulven SM, Brantsæter AL, Retterstøl K, Brekke HK, Michelsen TM, Henriksen T, Roeters van Lennep JE, Magnus P, Veierød MB, Holven KB (2021)
Novel associations between parental and newborn cord blood metabolic profiles in the Norwegian Mother, Father and Child Cohort Study
BMC Med, 19 (1), 91
DOI 10.1186/s12916-021-01959-w, PubMed 33849542

Rodríguez-Borjabad C, Narveud I, Christensen JJ, Ulven SM, Malo AI, Ibarretxe D, Girona J, Torvik K, Bogsrud MP, Retterstøl K, Plana N, Masana L, Holven KB (2021)
Dietary intake and lipid levels in Norwegian and Spanish children with familial hypercholesterolemia
Nutr Metab Cardiovasc Dis, 31 (4), 1299-1307
DOI 10.1016/j.numecd.2020.12.002, PubMed 33549456

Rootwelt-Norberg C, Lie ØH, Chivulescu M, Castrini AI, Sarvari SI, Lyseggen E, Almaas VM, Bogsrud MP, Edvardsen T, Haugaa KH (2021)
Sex differences in disease progression and arrhythmic risk in patients with arrhythmogenic cardiomyopathy
Europace (in press)
DOI 10.1093/europace/euab077, PubMed 33829244

Publications 2020

Bogsrud MP, Øyri LKL, Halvorsen S, Atar D, Leren TP, Holven KB (2020)
Prevalence of genetically verified familial hypercholesterolemia among young (<45 years) Norwegian patients hospitalized with acute myocardial infarction
J Clin Lipidol, 14 (3), 339-345
DOI 10.1016/j.jacl.2020.04.002, PubMed 32418822

Hovland A, Narverud I, Lie Øyri LK, Bogsrud MP, Aagnes I, Ueland T, Mulder M, Leijten F, Langslet G, Wium C, Svilaas A, Arnesen KE, Roeters van Lennep J, Aukrust P, Halvorsen B, Retterstøl K, Holven KB (2020)
Subjects with familial hypercholesterolemia have lower aortic valve area and higher levels of inflammatory biomarkers
J Clin Lipidol, 15 (1), 134-141
DOI 10.1016/j.jacl.2020.12.006, PubMed 33358307

Mundal LJ, Hovland A, Igland J, Vetrhus M, Veierød MB, Holven KB, Bogsrud MP, Tell GS, Leren TP, Retterstøl K (2020)
Increased risk of peripheral artery disease in persons with familial hypercholesterolaemia: a prospective registry study
Eur J Prev Cardiol (in press)
DOI 10.1093/eurjpc/zwaa024, PubMed 33623989

Representatives of the Global Familial Hypercholesterolemia Community, Wilemon KA, Patel J, Aguilar-Salinas C, Ahmed CD, Alkhnifsawi M, Almahmeed W, Alonso R, Al-Rasadi K, Badimon L, Bernal LM, Bogsrud MP, Braun LT, Brunham L, Catapano AL, Cillíková K, Corral P, Cuevas R, Defesche JC, Descamps OS, de Ferranti S, Eiselé JL, Elikir G, Folco E, Freiberger T et al. (2020)
Reducing the Clinical and Public Health Burden of Familial Hypercholesterolemia: A Global Call to Action
JAMA Cardiol, 5 (2), 217-229
DOI 10.1001/jamacardio.2019.5173, PubMed 31895433

Svendsen K, Krogh HW, Igland J, Tell GS, Mundal LJ, Holven KB, Bogsrud MP, Leren TP, Retterstøl K (2020)
2.5-fold increased risk of recurrent acute myocardial infarction with familial hypercholesterolemia
Atherosclerosis, 319, 28-34
DOI 10.1016/j.atherosclerosis.2020.12.019, PubMed 33465659

Svendsen K, Langslet G, Krogh HW, Brinck J, Klausen IC, Stenehjem JS, Holven KB, Bogsrud MP, Retterstøl K (2020)
Genetic testing is essential for initiating statin therapy in children with familial hypercholesterolemia: Examples from Scandinavia
Atherosclerosis, 316, 48-52
DOI 10.1016/j.atherosclerosis.2020.11.027, PubMed 33302044

Publications 2019

Ben-Omran T, Masana L, Kolovou G, Ariceta G, Nóvoa FJ, Lund AM, Bogsrud MP, Araujo M, Hussein O, Ibarretxe D, Sanchez-Hernández RM, Santos RD (2019)
Real-World Outcomes with Lomitapide Use in Paediatric Patients with Homozygous Familial Hypercholesterolaemia
Adv Ther, 36 (7), 1786-1811
DOI 10.1007/s12325-019-00985-8, PubMed 31102204

Bogsrud MP, Græsdal A, Johansen D, Langslet G, Hovland A, Arnesen KE, Mundal LJ, Retterstøl K, Wium C, Holven KB (2019)
LDL-cholesterol goal achievement, cardiovascular disease, and attributed risk of Lp(a) in a large cohort of predominantly genetically verified familial hypercholesterolemia
J Clin Lipidol, 13 (2), 279-286
DOI 10.1016/j.jacl.2019.01.010, PubMed 30910667

Holven KB, Ulven SM, Bogsrud MP (2019)
Editorial Comment: Hyperlipidaemia and cardiovascular disease and impact of early cholesterol accumulation
Curr Opin Lipidol, 30 (6), 490-493
DOI 10.1097/MOL.0000000000000646, PubMed 31688171

Krogh HW, Svendsen K, Igland J, Mundal LJ, Holven KB, Bogsrud MP, Leren TP, Retterstøl K (2019)
Lower risk of smoking-related cancer in individuals with familial hypercholesterolemia compared with controls: a prospective matched cohort study
Sci Rep, 9 (1), 19273
DOI 10.1038/s41598-019-55682-x, PubMed 31848411

Mundal LJ, Hovland A, Igland J, Veierød MB, Holven KB, Bogsrud MP, Tell GS, Leren TP, Retterstøl K (2019)
Association of Low-Density Lipoprotein Cholesterol With Risk of Aortic Valve Stenosis in Familial Hypercholesterolemia
JAMA Cardiol, 4 (11), 1156-1159
DOI 10.1001/jamacardio.2019.3903, PubMed 31617858

Narverud I, Bogsrud MP, Øyri LKL, Ulven SM, Retterstøl K, Ueland T, Mulder M, Roeters van Lennep J, Halvorsen B, Aukrust P, Veierød MB, Holven KB (2019)
Lipoprotein(a) concentration is associated with plasma arachidonic acid in subjects with familial hypercholesterolaemia
Br J Nutr, 122 (7), 790-799
DOI 10.1017/S0007114519001600, PubMed 31262370

Narverud I, Christensen JJ, Bakke SS, Ulven SM, Rundblad A, Aukrust P, Espevik T, Bogsrud MP, Retterstøl K, Ueland T, Halvorsen B, Holven KB (2019)
Profiling of immune-related gene expression in children with familial hypercholesterolaemia
J Intern Med, 287 (3), 310-321
DOI 10.1111/joim.13001, PubMed 31631426

Øyri LKL, Bogsrud MP, Kristiansen AL, Myhre JB, Retterstøl K, Brekke HK, Gundersen TE, Andersen LF, Holven KB (2019)
Infant cholesterol and glycated haemoglobin concentrations vary widely-Associations with breastfeeding, infant diet and maternal biomarkers
Acta Paediatr, 109 (1), 115-121
DOI 10.1111/apa.14936, PubMed 31299108

Øyri LKL, Narverud I, Bogsrud MP, Hansson P, Leder L, Byfuglien MG, Veierød MB, Thoresen M, Ulven SM, Holven KB (2019)
Postprandial changes in gene expression of cholesterol influx and efflux mediators after intake of SFA compared with n-6 PUFA in subjects with and without familial hypercholesterolaemia: secondary outcomes of a randomised controlled trial
J Nutr Sci, 8, e27
DOI 10.1017/jns.2019.25, PubMed 31448116

Ramaswami U, Futema M, Bogsrud MP, Holven KB, Roeters van Lennep J, Wiegman A, Descamps OS, Vrablik M, Freiberger T, Dieplinger H, Greber-Platzer S, Hanauer-Mader G, Bourbon M, Drogari E, Humphries SE (2019)
Comparison of the characteristics at diagnosis and treatment of children with heterozygous familial hypercholesterolaemia (FH) from eight European countries
Atherosclerosis, 292, 178-187
DOI 10.1016/j.atherosclerosis.2019.11.012, PubMed 31809987

Publications 2018

EAS Familial Hypercholesterolaemia Studies Collaboration, Vallejo-Vaz AJ, De Marco M, Stevens CAT, Akram A, Freiberger T, Hovingh GK, Kastelein JJP, Mata P, Raal FJ, Santos RD, Soran H, Watts GF, Abifadel M, Aguilar-Salinas CA, Al-Khnifsawi M, AlKindi FA, Alnouri F, Alonso R, Al-Rasadi K, Al-Sarraf A, Ashavaid TF, Binder CJ, Bogsrud MP, Bourbon M et al. (2018)
Overview of the current status of familial hypercholesterolaemia care in over 60 countries - The EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)
Atherosclerosis, 277, 234-255
DOI 10.1016/j.atherosclerosis.2018.08.051, PubMed 30270054

Holven KB, Narverud I, van Lennep JR, Versmissen J, Øyri LKL, Galema-Boers A, Langslet G, Ulven SM, Veierød MB, Retterstøl K, Bogsrud MP (2018)
Sex differences in cholesterol levels from birth to 19 years of age may lead to increased cholesterol burden in females with FH
J Clin Lipidol, 12 (3), 748-755.e2
DOI 10.1016/j.jacl.2018.02.021, PubMed 29609857

Hovland A, Mundal LJ, Igland J, Veierød MB, Holven KB, Bogsrud MP, Tell GS, Leren TP, Retterstøl K (2018)
Risk of Ischemic Stroke and Total Cerebrovascular Disease in Familial Hypercholesterolemia
Stroke, 50 (1), 172-174
DOI 10.1161/STROKEAHA.118.023456, PubMed 30580708

Langslet G, Bogsrud MP, Wium C, Johansen D, Svilaas A, Holven KB (2018)
Some children with a familial hypercholesterolemia mutation may exhibit persistent low LDL levels
J Clin Lipidol, 12 (5), 1327-1328
DOI 10.1016/j.jacl.2018.06.012, PubMed 30033003

Øyri LKL, Hansson P, Bogsrud MP, Narverud I, Florholmen G, Leder L, Byfuglien MG, Veierød MB, Ulven SM, Holven KB (2018)
Delayed postprandial TAG peak after intake of SFA compared with PUFA in subjects with and without familial hypercholesterolaemia: a randomised controlled trial
Br J Nutr, 119 (10), 1142-1150
DOI 10.1017/S0007114518000673, PubMed 29759104

Øyri LKL, Hansson P, Bogsrud MP, Narverud I, Florholmen G, Leder L, Byfuglien MG, Veierød MB, Ulven SM, Holven KB (2018)
Delayed postprandial TAG peak after intake of SFA compared with PUFA in subjects with and without familial hypercholesterolaemia: a randomised controlled trial
Br J Nutr, 120 (5), 597
DOI 10.1017/S0007114518001769, PubMed 30047345

Publications 2017

Bogsrud MP, Græsdal A, Retterstøl K, Holven KB (2017)
A physically fit woman in her thirties with exertional dyspnoea
Tidsskr Nor Laegeforen, 137 (6), 456-458
DOI 10.4045/tidsskr.16.0538, PubMed 28332800

Bogsrud MP, Langslet G, Wium C, Johansen D, Svilaas A, Holven KB (2017)
Treatment goal attainment in children with familial hypercholesterolemia: A cohort study of 302 children in Norway
J Clin Lipidol, 12 (2), 375-382
DOI 10.1016/j.jacl.2017.11.009, PubMed 29310990

Christensen JJ, Ulven SM, Retterstøl K, Narverud I, Bogsrud MP, Henriksen T, Bollerslev J, Halvorsen B, Aukrust P, Holven KB (2017)
Comprehensive lipid and metabolite profiling of children with and without familial hypercholesterolemia: A cross-sectional study
Atherosclerosis, 266, 48-57
DOI 10.1016/j.atherosclerosis.2017.09.021, PubMed 28963918

Holven KB, Ulven SM, Bogsrud MP (2017)
Hyperlipidemia and cardiovascular disease with focus on familial hypercholesterolemia
Curr Opin Lipidol, 28 (5), 445-447
DOI 10.1097/MOL.0000000000000449, PubMed 28857860

Hovland A, Mundal LJ, Igland J, Veierød MB, Holven KB, Bogsrud MP, Tell GS, Leren TP, Retterstøl K (2017)
Increased risk of heart failure and atrial fibrillation in heterozygous familial hypercholesterolemia
Atherosclerosis, 266, 69-73
DOI 10.1016/j.atherosclerosis.2017.09.027, PubMed 28992466

Publications 2016

Bogsrud MP, Ulven SM, Holven KB (2016)
Does intrauterine exposure to hypercholesterolemia adversely affect familial hypercholesterolemia phenotype?
Curr Opin Lipidol, 27 (4), 382-7
DOI 10.1097/MOL.0000000000000299, PubMed 27070077

Christensen JJ, Osnes L, Halvorsen B, Retterstøl K, Bogsrud MP, Wium C, Svilaas A, Narverud I, Ulven SM, Aukrust P, Holven KB (2016)
Data on circulating leukocyte subpopulations and inflammatory proteins in children with familial hypercholesterolemia and healthy children
Data Brief, 10, 587-592
DOI 10.1016/j.dib.2016.12.042, PubMed 28070551

Christensen JJ, Osnes LT, Halvorsen B, Retterstøl K, Bogsrud MP, Wium C, Svilaas A, Narverud I, Ulven SM, Aukrust P, Holven KB (2016)
Altered leukocyte distribution under hypercholesterolemia: A cross-sectional study in children with familial hypercholesterolemia
Atherosclerosis, 256, 67-74
DOI 10.1016/j.atherosclerosis.2016.11.031, PubMed 28024183

EAS Familial Hypercholesterolaemia Studies Collaboration, Vallejo-Vaz AJ, Akram A, Kondapally Seshasai SR, Cole D, Watts GF, Hovingh GK, Kastelein JJ, Mata P, Raal FJ, Santos RD, Soran H, Freiberger T, Abifadel M, Aguilar-Salinas CA, Alnouri F, Alonso R, Al-Rasadi K, Banach M, Bogsrud MP, Bourbon M, Bruckert E, Car J, Ceska R, Corral P et al. (2016)
Pooling and expanding registries of familial hypercholesterolaemia to assess gaps in care and improve disease management and outcomes: Rationale and design of the global EAS Familial Hypercholesterolaemia Studies Collaboration
Atheroscler Suppl, 22, 1-32
DOI 10.1016/j.atherosclerosissup.2016.10.001, PubMed 27939304

Publications 2015

Langslet G, Bogsrud MP, Halvorsen I, Fjeldstad H, Retterstøl K, Veierød MB, Ose L (2015)
Long-term follow-up of young adults with familial hypercholesterolemia after participation in clinical trials during childhood
J Clin Lipidol, 9 (6), 778-785
DOI 10.1016/j.jacl.2015.08.008, PubMed 26687698

Vallejo-Vaz AJ, Kondapally Seshasai SR, Cole D, Hovingh GK, Kastelein JJ, Mata P, Raal FJ, Santos RD, Soran H, Watts GF, Abifadel M, Aguilar-Salinas CA, Akram A, Alnouri F, Alonso R, Al-Rasadi K, Banach M, Bogsrud MP, Bourbon M, Bruckert E, Car J, Corral P, Descamps O, Dieplinger H, Durst R et al. (2015)
Familial hypercholesterolaemia: A global call to arms
Atherosclerosis, 243 (1), 257-9
DOI 10.1016/j.atherosclerosis.2015.09.021, PubMed 26408930

Publications 2013

Baumann M, Espeland MZ, Kværner AS, Bogsrud MP, Retterstøl K (2013)
[M. Baumann and colleagues replies]
Tidsskr Nor Laegeforen, 133 (16), 1685-6
DOI 10.4045/tidsskr.13.1023, PubMed 24005696

Baumann M, Espeland MZ, Kværner AS, Bogsrud MP, Retterstøl K (2013)
[Lipid profile of healthy persons with low-carbohydrate diet]
Tidsskr Nor Laegeforen, 133 (11), 1193-6
DOI 10.4045/tidsskr.12.0034, PubMed 23759780

Bogsrud MP, Langslet G, Ose L, Arnesen KE, Sm Stuen MC, Malt UF, Woldseth B, Retterstøl K (2013)
No effect of combined coenzyme Q10 and selenium supplementation on atorvastatin-induced myopathy
Scand Cardiovasc J, 47 (2), 80-7
DOI 10.3109/14017431.2012.756119, PubMed 23301875

Bogsrud MP, Reikvam Å, Retterstøl K (2013)
[Treatment with statins]
Tidsskr Nor Laegeforen, 133 (12-13), 1316-9
DOI 10.4045/tidsskr.12.0825, PubMed 23817262

Stormo C, Bogsrud MP, Hermann M, Åsberg A, Piehler AP, Retterstøl K, Kringen MK (2013)
UGT1A1*28 is associated with decreased systemic exposure of atorvastatin lactone
Mol Diagn Ther, 17 (4), 233-7
DOI 10.1007/s40291-013-0031-x, PubMed 23580084

Publications 2012

Cameron J, Bogsrud MP, Tveten K, Strøm TB, Holven K, Berge KE, Leren TP (2012)
Serum levels of proprotein convertase subtilisin/kexin type 9 in subjects with familial hypercholesterolemia indicate that proprotein convertase subtilisin/kexin type 9 is cleared from plasma by low-density lipoprotein receptor-independent pathways
Transl Res, 160 (2), 125-30
DOI 10.1016/j.trsl.2012.01.010, PubMed 22683370

Græsdal A, Bogsrud MP, Holven KB, Nenseter MS, Narverud I, Langslet G, Brekke M, Retterstøl K, Arnesen KE, Ose L (2012)
Apheresis in homozygous familial hypercholesterolemia: the results of a follow-up of all Norwegian patients with homozygous familial hypercholesterolemia
J Clin Lipidol, 6 (4), 331-9
DOI 10.1016/j.jacl.2012.03.004, PubMed 22836070

Nenseter MS, Bogsrud MP, Græsdal A, Narverud I, Halvorsen B, Ose L, Aukrust P, Holven KB (2012)
LDL-apheresis affects markers of endothelial function in patients with homozygous familial hypercholesterolemia
Thromb Res, 130 (5), 823-5
DOI 10.1016/j.thromres.2012.06.004, PubMed 22728023

Nenseter MS, Narverud I, Græsdal A, Bogsrud MP, Aukrust P, Retterstøl K, Ose L, Halvorsen B, Holven KB (2012)
Cholesterol efflux mediators in homozygous familial hypercholesterolemia patients on low-density lipoprotein apheresis
J Clin Lipidol, 7 (2), 109-16
DOI 10.1016/j.jacl.2012.08.001, PubMed 23415429

Nenseter MS, Narverud I, Græsdal A, Bogsrud MP, Halvorsen B, Ose L, Aukrust P, Holven KB (2012)
Elevated serum MMP-9/TIMP-1 ratio in patients with homozygous familial hypercholesterolemia: effects of LDL-apheresis
Cytokine, 61 (1), 194-8
DOI 10.1016/j.cyto.2012.09.016, PubMed 23131422

Publications 2011

Skottheim IB, Bogsrud MP, Hermann M, Retterstøl K, Åsberg A (2011)
Atorvastatin metabolite measurements as a diagnostic tool for statin-induced myopathy
Mol Diagn Ther, 15 (4), 221-7
DOI 10.1007/BF03256413, PubMed 21815705

Publications 2010

Bogsrud MP, Ose L, Langslet G, Ottestad I, Strøm EC, Hagve TA, Retterstøl K (2010)
HypoCol (red yeast rice) lowers plasma cholesterol - a randomized placebo controlled study
Scand Cardiovasc J, 44 (4), 197-200
DOI 10.3109/14017431003624123, PubMed 20636227

Kulseth MA, Berge KE, Bogsrud MP, Leren TP (2010)
Analysis of LDLR mRNA in patients with familial hypercholesterolemia revealed a novel mutation in intron 14, which activates a cryptic splice site
J Hum Genet, 55 (10), 676-80
DOI 10.1038/jhg.2010.87, PubMed 20703241

Publications 2007

Bogsrud MP, Sogstad A, Retterstøl K (2007)
[Practical advice for registration of clinical trials]
Tidsskr Nor Laegeforen, 127 (12), 1654-6
PubMed 17571106

Publications 2006

Hermann M, Bogsrud MP, Molden E, Asberg A, Mohebi BU, Ose L, Retterstøl K (2006)
Exposure of atorvastatin is unchanged but lactone and acid metabolites are increased several-fold in patients with atorvastatin-induced myopathy
Clin Pharmacol Ther, 79 (6), 532-9
DOI 10.1016/j.clpt.2006.02.014, PubMed 16765141