Publications from OUS - Dept. of Microbiology, Klungland - Lab for dynamic gene regulation

168 publications found

Publications 2024

1. Barker-Clarke RJ, Gray JM, Strobl MAR, Tadele DS, Maltas J, Hinczewski M, Scott JG (2024)
   The balance between intrinsic and ecological fitness defines new regimes in eco-evolutionary population dynamics
   bioRxiv
   DOI 10.1101/2023.03.15.532871, PubMed 36993598
2. Holland P, Istre M, Ali MM, Gedde-Dahl T, Buechner J, Wildhagen M, Brunvoll SH, Horvath S, Matsuyama S, Dahl JA, Stölzel F, Søraas A (2024)
   Epigenetic aging of human blood cells is influenced by the age of the host body
   Aging Cell, 23 (5), e14112
   DOI 10.1111/acel.14112, PubMed 38439206
3. Ougland R, Kleve G (2024)
   Cancer pathways may be too rushed
   Tidsskr Nor Laegeforen, 144 (13)
   DOI 10.4045/tidsskr.24.0467, PubMed 39498646

Publications 2023

1. Bali N, Brennhaug SJ, Bjørås M, Bandyopadhyay S, Manaf A (2023)
   Optimized synthesis of polyacrylic acid-coated magnetic nanoparticles for high-efficiency DNA isolation and size selection
   RSC Adv, 13 (42), 29109-29120
   DOI 10.1039/d3ra04687g, PubMed 37800135
2. Isachesku E, Braicu C, Pirlog R, Kocijancic A, Busuioc C, Pruteanu LL, Pandey DP, Berindan-Neagoe I (2023)
   The Role of Non-Coding RNAs in Epigenetic Dysregulation in Glioblastoma Development
   Int J Mol Sci, 24 (22)
   DOI 10.3390/ijms242216320, PubMed 38003512
3. Li Y, Wang Y, Vera-Rodriguez M, Lindeman LC, Skuggen LE, Rasmussen EMK, Jermstad I, Khan S, Fosslie M, Skuland T, Indahl M, Khodeer S, Klemsdal EK, Jin KX, Dalen KT, Fedorcsak P, Greggains GD, Lerdrup M, Klungland A, Au KF, Dahl JA (2023)
   Single-cell m⁶A mapping in vivo using picoMeRIP-seq
   Nat Biotechnol, 42 (4), 591-596
   DOI 10.1038/s41587-023-01831-7, PubMed 37349523
4. Starheim EJ, Ravlo E, Schjølberg JO, Solvang V, Wang W, Scrimgeour NR, Manaf A, Erlandsen SE, Aas PA, Hagen L, de Sousa MML, Bjørås M (2023)
   NAxtra magnetic nanoparticles for low-cost, efficient isolation of mammalian DNA and RNA
   Sci Rep, 13 (1), 20836
   DOI 10.1038/s41598-023-46868-5, PubMed 38012172
5. Tislevoll BS, Hellesøy M, Fagerholt OHE, Gullaksen SE, Srivastava A, Birkeland E, Kleftogiannis D, Ayuda-Durán P, Piechaczyk L, Tadele DS, Skavland J, Baliakas P, Hovland R, Andresen V, Seternes OM, Tvedt THA, Aghaeepour N, Gavasso S, Porkka K, Jonassen I, Fløisand Y, Enserink J, Blaser N, Gjertsen BT (2023)
   Author Correction: Early response evaluation by single cell signaling profiling in acute myeloid leukemia
   Nat Commun, 14 (1), 1767
   DOI 10.1038/s41467-023-37488-8, PubMed 36997540
6. Wang Y, Li Y, Skuland T, Zhou C, Li A, Hashim A, Jermstad I, Khan S, Dalen KT, Greggains GD, Klungland A, Dahl JA, Au KF (2023)
   The RNA m⁶A landscape of mouse oocytes and preimplantation embryos
   Nat Struct Mol Biol, 30 (5), 703-709
   DOI 10.1038/s41594-023-00969-x, PubMed 37081317

Publications 2022

1. Ellingjord-Dale M, Kalleberg KT, Istre MS, Nygaard AB, Brunvoll SH, Eggesbø LM, Dahl JA, Kjetland EF, Ursin G, Søraas A (2022)
   The use of public transport and contraction of SARS-CoV-2 in a large prospective cohort in Norway
   BMC Infect Dis, 22 (1), 252
   DOI 10.1186/s12879-022-07233-5, PubMed 35287611
2. Hansen AM, Ge Y, Schuster MB, Pundhir S, Jakobsen JS, Kalvisa A, Tapia MC, Gordon S, Ambri F, Bagger FO, Pandey D, Helin K, Porse BT (2022)
   H3K9 dimethylation safeguards cancer cells against activation of the interferon pathway
   Sci Adv, 8 (11), eabf8627
   DOI 10.1126/sciadv.abf8627, PubMed 35302840
3. Holland P, Wildhagen M, Istre M, Reiakvam OM, Dahl JA, Søraas A (2022)
   Cri du chat syndrome patients have DNA methylation changes in genes linked to symptoms of the disease
   Clin Epigenetics, 14 (1), 128
   DOI 10.1186/s13148-022-01350-3, PubMed 36242045
4. Khodeer S, Klungland A, Dahl JA (2022)
   ALKBH5 regulates somatic cell reprogramming in a phase-specific manner
   J Cell Sci, 135 (11)
   DOI 10.1242/jcs.259824, PubMed 35552718
5. Li M, Klungland A, Dalhus B (2022)
   Studies on Protein-RNA:DNA Hybrid Interactions by Microscale Thermophoresis (MST)
   Methods Mol Biol, 2528, 239-251
   DOI 10.1007/978-1-0716-2477-7_15, PubMed 35704195
6. Lång E, Pedersen C, Lång A, Blicher P, Klungland A, Carlson A, Bøe SO (2022)
   Mechanical coupling of supracellular stress amplification and tissue fluidization during exit from quiescence
   Proc Natl Acad Sci U S A, 119 (32), e2201328119
   DOI 10.1073/pnas.2201328119, PubMed 35914175
7. Rognes T, Scheffer L, Greiff V, Sandve GK (2022)
   CompAIRR: ultra-fast comparison of adaptive immune receptor repertoires by exact and approximate sequence matching
   Bioinformatics, 38 (17), 4230-4232
   DOI 10.1093/bioinformatics/btac505, PubMed 35852318
8. Rossini R, Kumar V, Mathelier A, Rognes T, Paulsen J (2022)
   MoDLE: high-performance stochastic modeling of DNA loop extrusion interactions
   Genome Biol, 23 (1), 247
   DOI 10.1186/s13059-022-02815-7, PubMed 36451166
9. Su Z, Monshaugen I, Klungland A, Ougland R, Dutta A (2022)
   Characterization of novel small non-coding RNAs and their modifications in bladder cancer using an updated small RNA-seq workflow
   Front Mol Biosci, 9, 887686
   DOI 10.3389/fmolb.2022.887686, PubMed 35923465
10. Su Z, Monshaugen I, Wilson B, Wang F, Klungland A, Ougland R, Dutta A (2022)
    TRMT6/61A-dependent base methylation of tRNA-derived fragments regulates gene-silencing activity and the unfolded protein response in bladder cancer
    Nat Commun, 13 (1), 2165
    DOI 10.1038/s41467-022-29790-8, PubMed 35444240
11. Sui X, Klungland A, Gao L (2022)
    RNA m6A modifications in mammalian gametogenesis and pregnancy
    Reproduction, 165 (1), R1-R8
    DOI 10.1530/REP-22-0112, PubMed 36194446
12. Zhao X, Hendriks IA, Le Gras S, Ye T, Ramos-Alonso L, Nguéa P A, Lien GF, Ghasemi F, Klungland A, Jost B, Enserink JM, Nielsen ML, Chymkowitch P (2022)
    Waves of sumoylation support transcription dynamics during adipocyte differentiation
    Nucleic Acids Res, 50 (3), 1351-1369
    DOI 10.1093/nar/gkac027, PubMed 35100417

Publications 2021

1. Alexeeva M, Moen MN, Xu XM, Rasmussen A, Leiros I, Kirpekar F, Klungland A, Alsøe L, Nilsen H, Bjelland S (2021)
   Intrinsic Strand-Incision Activity of Human UNG: Implications for Nick Generation in Immunoglobulin Gene Diversification
   Front Immunol, 12, 762032
   DOI 10.3389/fimmu.2021.762032, PubMed 35003074
2. Eriksson AM, Leikfoss IS, Abrahamsen G, Sundvold V, Isom MM, Keshari PK, Rognes T, Landsverk OJB, Bos SD, Harbo HF, Spurkland A, Berge T (2021)
   Exploring the role of the multiple sclerosis susceptibility gene CLEC16A in T cells
   Scand J Immunol, 94 (1), e13050
   DOI 10.1111/sji.13050, PubMed 34643957
3. Hildrestrand GA, Rolseth V, Kunath N, Suganthan R, Jensen V, Bugaj AM, Fernandez-Berrocal MS, Sikko SB, Vetlesen S, Kuśnierczyk A, Olsen AK, Gützkow KB, Rowe AD, Wang W, Moldestad O, Syrstad MD, Slupphaug G, Eide L, Klungland A, Sætrom P, Luna L, Ye J, Scheffler K, Bjørås M (2021)
   NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice
   Commun Biol, 4 (1), 1354
   DOI 10.1038/s42003-021-02864-x, PubMed 34857879
4. Jaroy EG, Emblem R, Reims HM, Mai TT, Risa GT, Ougland R (2021)
   Evaluation of diagnostic factors used to refer children with constipation for rectal biopsies
   Int J Colorectal Dis, 37 (3), 597-605
   DOI 10.1007/s00384-021-04069-4, PubMed 34882271
5. Jiang X, Bergquist A, Löscher BS, Venkatesh G, Mold JE, Holm K, Laerdahl JK, Skånland SS, Maleki KT, Cornillet M, Taskén K, Franke A, Karlsen TH, Björkström NK, Melum E (2021)
   A heterozygous germline CD100 mutation in a family with primary sclerosing cholangitis
   Sci Transl Med, 13 (582)
   DOI 10.1126/scitranslmed.abb0036, PubMed 33627483
6. Jin KX, Zuo R, Anastassiadis K, Klungland A, Marr C, Filipczyk A (2021)
   N6-methyladenosine (m⁶A) depletion regulates pluripotency exit by activating signaling pathways in embryonic stem cells
   Proc Natl Acad Sci U S A, 118 (51)
   DOI 10.1073/pnas.2105192118, PubMed 34921114
7. Kværner AS, Birkeland E, Bucher-Johannessen C, Vinberg E, Nordby JI, Kangas H, Bemanian V, Ellonen P, Botteri E, Natvig E, Rognes T, Hovig E, Lyle R, Ambur OH, de Vos WM, Bultman S, Hjartåker A, Landberg R, Song M, Blix HS, Ursin G, Randel KR, de Lange T, Hoff G, Holme Ø et al. (2021)
   The CRCbiome study: a large prospective cohort study examining the role of lifestyle and the gut microbiome in colorectal cancer screening participants
   BMC Cancer, 21 (1), 930
   DOI 10.1186/s12885-021-08640-8, PubMed 34407780
8. Mahé F, Czech L, Stamatakis A, Quince C, de Vargas C, Dunthorn M, Rognes T (2021)
   Swarm v3: towards tera-scale amplicon clustering
   Bioinformatics, 38 (1), 267-269
   DOI 10.1093/bioinformatics/btab493, PubMed 34244702
9. Sharma S, Mukherjee AK, Roy SS, Bagri S, Lier S, Verma M, Sengupta A, Kumar M, Nesse G, Pandey DP, Chowdhury S (2021)
   Human telomerase is directly regulated by non-telomeric TRF2-G-quadruplex interaction
   Cell Rep, 35 (7), 109154
   DOI 10.1016/j.celrep.2021.109154, PubMed 34010660
10. Tesfahun AN, Alexeeva M, Tomkuvienė M, Arshad A, Guragain P, Klungland A, Klimašauskas S, Ruoff P, Bjelland S (2021)
    Alleviation of C⋅C Mismatches in DNA by the Escherichia coli Fpg Protein
    Front Microbiol, 12, 608839
    DOI 10.3389/fmicb.2021.608839, PubMed 34276575
11. Zhang LS, Xiong QP, Peña Perez S, Liu C, Wei J, Le C, Zhang L, Harada BT, Dai Q, Feng X, Hao Z, Wang Y, Dong X, Hu L, Wang ED, Pan T, Klungland A, Liu RJ, He C (2021)
    ALKBH7-mediated demethylation regulates mitochondrial polycistronic RNA processing
    Nat Cell Biol, 23 (7), 684-691
    DOI 10.1038/s41556-021-00709-7, PubMed 34253897

Publications 2020

1. Backe PH, Laerdahl JK, Kittelsen LS, Dalhus B, Mørkrid L, Bjørås M (2020)
   Structural basis for substrate and product recognition in human phosphoglucomutase-1 (PGM1) isoform 2, a member of the α-D-phosphohexomutase superfamily
   Sci Rep, 10 (1), 5656
   DOI 10.1038/s41598-020-62548-0, PubMed 32221390
2. Farooq A, Grønmyr S, Ali O, Rognes T, Scheffler K, Bjørås M, Wang J (2020)
   HMST-Seq-Analyzer: A new python tool for differential methylation and hydroxymethylation analysis in various DNA methylation sequencing data
   Comput Struct Biotechnol J, 18, 2877-2889
   DOI 10.1016/j.csbj.2020.09.038, PubMed 33163148
3. Grøsvik K, Tesfahun AN, Muruzábal-Lecumberri I, Haugland GT, Leiros I, Ruoff P, Kvaløy JT, Knævelsrud I, Ånensen H, Alexeeva M, Sato K, Matsuda A, Alseth I, Klungland A, Bjelland S (2020)
   The Escherichia coli alkA Gene Is Activated to Alleviate Mutagenesis by an Oxidized Deoxynucleoside
   Front Microbiol, 11, 263
   DOI 10.3389/fmicb.2020.00263, PubMed 32158436
4. Khelik K, Sandve GK, Nederbragt AJ, Rognes T (2020)
   NucBreak: location of structural errors in a genome assembly by using paired-end Illumina reads
   BMC Bioinformatics, 21 (1), 66
   DOI 10.1186/s12859-020-3414-0, PubMed 32085722
5. Kong XY, Vik ES, Nawaz MS, Berges N, Dahl TB, Vågbø C, Suganthan R, Segers F, Holm S, Quiles-Jiménez A, Gregersen I, Fladeby C, Aukrust P, Bjørås M, Klungland A, Halvorsen B, Alseth I (2020)
   Deletion of Endonuclease V suppresses chemically induced hepatocellular carcinoma
   Nucleic Acids Res, 48 (8), 4463-4479
   DOI 10.1093/nar/gkaa115, PubMed 32083667
6. Li M, Klungland A (2020)
   Modifications and interactions at the R-loop
   DNA Repair (Amst), 96, 102958
   DOI 10.1016/j.dnarep.2020.102958, PubMed 32961406
7. Matsuyama M, Søraas A, Yu S, Kim K, Stavrou EX, Caimi PF, Wald D, deLima M, Dahl JA, Horvath S, Matsuyama S (2020)
   Analysis of epigenetic aging in vivo and in vitro: Factors controlling the speed and direction
   Exp Biol Med (Maywood), 245 (17), 1543-1551
   DOI 10.1177/1535370220947015, PubMed 32762265
8. Sankar A, Lerdrup M, Manaf A, Johansen JV, Gonzalez JM, Borup R, Blanshard R, Klungland A, Hansen K, Andersen CY, Dahl JA, Helin K, Hoffmann ER (2020)
   KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes
   Nat Cell Biol, 22 (4), 380-388
   DOI 10.1038/s41556-020-0494-z, PubMed 32231309
9. Saue T, Bast R, Gomes ASP, Jensen HJA, Visscher L, Aucar IA, Di Remigio R, Dyall KG, Eliav E, Fasshauer E, Fleig T, Halbert L, Hedegård ED, Helmich-Paris B, Iliaš M, Jacob CR, Knecht S, Laerdahl JK, Vidal ML, Nayak MK, Olejniczak M, Olsen JMH, Pernpointner M, Senjean B, Shee A et al. (2020)
   The DIRAC code for relativistic molecular calculations
   J Chem Phys, 152 (20), 204104
   DOI 10.1063/5.0004844, PubMed 32486677
10. Vander Zanden CM, Czarny RS, Ho EN, Robertson AB, Ho PS (2020)
    Structural adaptation of vertebrate endonuclease G for 5-hydroxymethylcytosine recognition and function
    Nucleic Acids Res, 48 (7), 3962-3974
    DOI 10.1093/nar/gkaa117, PubMed 32095813
11. Yang M, Lin X, Segers F, Suganthan R, Hildrestrand GA, Rinholm JE, Aas PA, Sousa MML, Holm S, Bolstad N, Warren D, Berge RK, Johansen RF, Yndestad A, Kristiansen E, Klungland A, Luna L, Eide L, Halvorsen B, Aukrust P, Bjørås M (2020)
    OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation
    Cell Rep, 30 (12), 4165-4178.e7
    DOI 10.1016/j.celrep.2020.02.063, PubMed 32209476
12. Zwiggelaar RT, Lindholm HT, Fosslie M, Terndrup Pedersen M, Ohta Y, Díez-Sánchez A, Martín-Alonso M, Ostrop J, Matano M, Parmar N, Kvaløy E, Spanjers RR, Nazmi K, Rye M, Drabløs F, Arrowsmith C, Arne Dahl J, Jensen KB, Sato T, Oudhoff MJ (2020)
    LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium
    Sci Adv, 6 (37)
    DOI 10.1126/sciadv.abc0367, PubMed 32917713

Publications 2019

1. Abakir A, Giles TC, Cristini A, Foster JM, Dai N, Starczak M, Rubio-Roldan A, Li M, Eleftheriou M, Crutchley J, Flatt L, Young L, Gaffney DJ, Denning C, Dalhus B, Emes RD, Gackowski D, Corrêa IR, Garcia-Perez JL, Klungland A, Gromak N, Ruzov A (2019)
   N⁶-methyladenosine regulates the stability of RNA:DNA hybrids in human cells
   Nat Genet, 52 (1), 48-55
   DOI 10.1038/s41588-019-0549-x, PubMed 31844323
2. Alexeeva M, Moen MN, Grøsvik K, Tesfahun AN, Xu XM, Muruzábal-Lecumberri I, Olsen KM, Rasmussen A, Ruoff P, Kirpekar F, Klungland A, Bjelland S (2019)
   Excision of uracil from DNA by hSMUG1 includes strand incision and processing
   Nucleic Acids Res, 47 (2), 779-793
   DOI 10.1093/nar/gky1184, PubMed 30496516
3. Berges N, Nawaz MS, Børresdatter Dahl T, Hagen L, Bjørås M, Laerdahl JK, Alseth I (2019)
   Complex alternative splicing of human Endonuclease V mRNA, but evidence for only a single protein isoform
   PLoS One, 14 (11), e0225081
   DOI 10.1371/journal.pone.0225081, PubMed 31703097
4. Fosslie M, Manaf A, Lerdrup M, Hansen K, Gilfillan GD, Dahl JA (2019)
   Going low to reach high: Small-scale ChIP-seq maps new terrain
   Wiley Interdiscip Rev Syst Biol Med, 12 (1), e1465
   DOI 10.1002/wsbm.1465, PubMed 31478357
5. Jaroy EG, Acosta-Jimenez L, Hotta R, Goldstein AM, Emblem R, Klungland A, Ougland R (2019)
   "Too much guts and not enough brains": (epi)genetic mechanisms and future therapies of Hirschsprung disease - a review
   Clin Epigenetics, 11 (1), 135
   DOI 10.1186/s13148-019-0718-x, PubMed 31519213
6. Lie-Jensen A, Ivanauskiene K, Malerød L, Jain A, Tan KW, Laerdahl JK, Liestøl K, Stenmark H, Haglund K (2019)
   Centralspindlin Recruits ALIX to the Midbody during Cytokinetic Abscission in Drosophila via a Mechanism Analogous to Virus Budding
   Curr Biol, 29 (20), 3538-3548.e7
   DOI 10.1016/j.cub.2019.09.025, PubMed 31607533
7. Pilžys T, Marcinkowski M, Kukwa W, Garbicz D, Dylewska M, Ferenc K, Mieczkowski A, Kukwa A, Migacz E, Wołosz D, Mielecki D, Klungland A, Piwowarski J, Poznański J, Grzesiuk E (2019)
   ALKBH overexpression in head and neck cancer: potential target for novel anticancer therapy
   Sci Rep, 9 (1), 13249
   DOI 10.1038/s41598-019-49550-x, PubMed 31519943
8. Prikrylova T, Robertson J, Ferrucci F, Konorska D, Aanes H, Manaf A, Zhang B, Vågbø CB, Kuśnierczyk A, Gilljam KM, Løvkvam-Køster C, Otterlei M, Dahl JA, Enserink J, Klungland A, Robertson AB (2019)
   5-hydroxymethylcytosine Marks Mammalian Origins Acting as a Barrier to Replication
   Sci Rep, 9 (1), 11065
   DOI 10.1038/s41598-019-47528-3, PubMed 31363131
9. Strøm TB, Vinje T, Bjune K, da Costa LT, Laerdahl JK, Leren TP (2019)
   Lysosomal acid lipase does not have a propeptide and should not be considered being a proprotein
   Proteins, 88 (3), 440-448
   DOI 10.1002/prot.25821, PubMed 31587363
10. Søraas A, Matsuyama M, de Lima M, Wald D, Buechner J, Gedde-Dahl T, Søraas CL, Chen B, Ferrucci L, Dahl JA, Horvath S, Matsuyama S (2019)
    Epigenetic age is a cell-intrinsic property in transplanted human hematopoietic cells
    Aging Cell, 18 (2), e12897
    DOI 10.1111/acel.12897, PubMed 30712319
11. Vinje T, Laerdahl JK, Bjune K, Leren TP, Strøm TB (2019)
    Characterization of the mechanisms by which missense mutations in the lysosomal acid lipase gene disrupt enzymatic activity
    Hum Mol Genet, 28 (18), 3043-3052
    DOI 10.1093/hmg/ddz114, PubMed 31131398
12. Zhang Z, Manaf A, Li Y, Perez SP, Suganthan R, Dahl JA, Bjørås M, Klungland A (2019)
    Histone Methylations Define Neural Stem/Progenitor Cell Subtypes in the Mouse Subventricular Zone
    Mol Neurobiol, 57 (2), 997-1008
    DOI 10.1007/s12035-019-01777-5, PubMed 31654318

Publications 2018

1. Alexeeva M, Guragain P, Tesfahun AN, Tomkuvienė M, Arshad A, Gerasimaitė R, Rukšėnaitė A, Urbanavičiūtė G, Bjørås M, Laerdahl JK, Klungland A, Klimašauskas S, Bjelland S (2018)
   Excision of the doubly methylated base N⁴,5-dimethylcytosine from DNA by Escherichia coli Nei and Fpg proteins
   Philos Trans R Soc Lond B Biol Sci, 373 (1748)
   DOI 10.1098/rstb.2017.0337, PubMed 29685966
2. Askeland G, Dosoudilova Z, Rodinova M, Klempir J, Liskova I, Kuśnierczyk A, Bjørås M, Nesse G, Klungland A, Hansikova H, Eide L (2018)
   Increased nuclear DNA damage precedes mitochondrial dysfunction in peripheral blood mononuclear cells from Huntington's disease patients
   Sci Rep, 8 (1), 9817
   DOI 10.1038/s41598-018-27985-y, PubMed 29959348
3. Askeland G, Rodinova M, Štufková H, Dosoudilova Z, Baxa M, Smatlikova P, Bohuslavova B, Klempir J, Nguyen TD, Kuśnierczyk A, Bjørås M, Klungland A, Hansikova H, Ellederova Z, Eide L (2018)
   A transgenic minipig model of Huntington's disease shows early signs of behavioral and molecular pathologies
   Dis Model Mech, 11 (10)
   DOI 10.1242/dmm.035949, PubMed 30254085
4. Bagger SO, Hopkinson BM, Pandey DP, Bak M, Brydholm AV, Villadsen R, Helin K, Rønnov-Jessen L, Petersen OW, Kim J (2018)
   Aggressiveness of non-EMT breast cancer cells relies on FBXO11 activity
   Mol Cancer, 17 (1), 171
   DOI 10.1186/s12943-018-0918-6, PubMed 30526604
5. Dahl JA, Gilfillan GD (2018)
   How low can you go? Pushing the limits of low-input ChIP-seq
   Brief Funct Genomics, 17 (2), 89-95
   DOI 10.1093/bfgp/elx037, PubMed 29087438
6. Gamage TH, Gunnes G, Lee RH, Louch WE, Holmgren A, Bruton JD, Lengle E, Kolstad TRS, Revold T, Amundsen SS, Dalen KT, Holme PA, Tjønnfjord GE, Christensen G, Westerblad H, Klungland A, Bergmeier W, Misceo D, Frengen E (2018)
   STIM1 R304W causes muscle degeneration and impaired platelet activation in mice
   Cell Calcium, 76, 87-100
   DOI 10.1016/j.ceca.2018.10.001, PubMed 30390422
7. Jantsch MF, Quattrone A, O'Connell M, Helm M, Frye M, Macias-Gonzales M, Ohman M, Ameres S, Willems L, Fuks F, Oulas A, Vanacova S, Nielsen H, Bousquet-Antonelli C, Motorin Y, Roignant JY, Balatsos N, Dinnyes A, Baranov P, Kelly V, Lamm A, Rechavi G, Pelizzola M, Liepins J, Holodnuka Kholodnyuk I et al. (2018)
   Positioning Europe for the EPITRANSCRIPTOMICS challenge
   RNA Biol, 15 (6), 829-831
   DOI 10.1080/15476286.2018.1460996, PubMed 29671387
8. Li M, Zhao X, Wang W, Shi H, Pan Q, Lu Z, Perez SP, Suganthan R, He C, Bjørås M, Klungland A (2018)
   Ythdf2-mediated m⁶A mRNA clearance modulates neural development in mice
   Genome Biol, 19 (1), 69
   DOI 10.1186/s13059-018-1436-y, PubMed 29855337
9. Ma C, Chang M, Lv H, Zhang ZW, Zhang W, He X, Wu G, Zhao S, Zhang Y, Wang D, Teng X, Liu C, Li Q, Klungland A, Niu Y, Song S, Tong WM (2018)
   RNA m⁶A methylation participates in regulation of postnatal development of the mouse cerebellum
   Genome Biol, 19 (1), 68
   DOI 10.1186/s13059-018-1435-z, PubMed 29855379
10. Skjærven KH, Jakt LM, Fernandes JMO, Dahl JA, Adam AC, Klughammer J, Bock C, Espe M (2018)
    Parental micronutrient deficiency distorts liver DNA methylation and expression of lipid genes associated with a fatty-liver-like phenotype in offspring
    Sci Rep, 8 (1), 3055
    DOI 10.1038/s41598-018-21211-5, PubMed 29445184
11. Wei J, Liu F, Lu Z, Fei Q, Ai Y, He PC, Shi H, Cui X, Su R, Klungland A, Jia G, Chen J, He C (2018)
    Differential m⁶A, m⁶A_m, and m¹A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm
    Mol Cell, 71 (6), 973-985.e5
    DOI 10.1016/j.molcel.2018.08.011, PubMed 30197295
12. Zhang B, Durán PA, Piechaczyk L, Fløisand Y, Safont MMS, Karlsen IT, Fandalyuk Z, Tadele D, Mierlo PV, Rowe AD, Robertson JM, Gjertsen BT, McCormack E, Enserink JM, Bjørn Tore Gjertsen Group, Emmet McCormack Group (2018)
    GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells
    Haematologica, Online ahead of print (in press) (Retracted)
    DOI 10.3324/haematol.2018.189399, PubMed 29748445

Publications 2017

1. Chymkowitch P, Nguéa P A, Aanes H, Robertson J, Klungland A, Enserink JM (2017)
   TORC1-dependent sumoylation of Rpc82 promotes RNA polymerase III assembly and activity
   Proc Natl Acad Sci U S A, 114 (5), 1039-1044
   DOI 10.1073/pnas.1615093114, PubMed 28096404
2. Jordan JJ, Chhim S, Margulies CM, Allocca M, Bronson RT, Klungland A, Samson LD, Fu D (2017)
   ALKBH7 drives a tissue and sex-specific necrotic cell death response following alkylation-induced damage
   Cell Death Dis, 8 (7), e2947
   DOI 10.1038/cddis.2017.343, PubMed 28726787
3. Kalikstad B, Kultima HG, Andersstuen TK, Klungland A, Isaksson A (2017)
   Gene expression profiles in preterm infants on continuous long‑term oxygen therapy suggest reduced oxidative stress‑dependent signaling during hypoxia
   Mol Med Rep, 15 (4), 1513-1526
   DOI 10.3892/mmr.2017.6185, PubMed 28259955
4. Landfors M, Johansen J, Aronsen JM, Vågbø CB, Doré LC, He C, Sjaastad I, Sætrom P, Fedorcsák P, Dahl JA, Aanes H, Fußer M, Klungland A (2017)
   Genome-wide profiling of DNA 5-hydroxymethylcytosine during rat Sertoli cell maturation
   Cell Discov, 3, 17013
   DOI 10.1038/celldisc.2017.13, PubMed 28529766
5. Malachin G, Reiten MR, Salvesen Ø, Aanes H, Kamstra JH, Skovgaard K, Heegaard PMH, Ersdal C, Espenes A, Tranulis MA, Bakkebø MK (2017)
   Loss of prion protein induces a primed state of type I interferon-responsive genes
   PLoS One, 12 (6), e0179881
   DOI 10.1371/journal.pone.0179881, PubMed 28651013
6. Olsen MB, Hildrestrand GA, Scheffler K, Vinge LE, Alfsnes K, Palibrk V, Wang J, Neurauter CG, Luna L, Johansen J, Øgaard JDS, Ohm IK, Slupphaug G, Kuśnierczyk A, Fiane AE, Brorson SH, Zhang L, Gullestad L, Louch WE, Iversen PO, Østlie I, Klungland A, Christensen G, Sjaastad I, Sætrom P et al. (2017)
   NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture
   Cell Rep, 18 (1), 82-92
   DOI 10.1016/j.celrep.2016.12.009, PubMed 28052262
7. Pawar T, Bjørås M, Klungland A, Eide L (2017)
   Metabolism and DNA repair shape a specific modification pattern in mitochondrial DNA
   Mitochondrion, 40, 16-28
   DOI 10.1016/j.mito.2017.09.002, PubMed 28893634
8. Rolseth V, Luna L, Olsen AK, Suganthan R, Scheffler K, Neurauter CG, Esbensen Y, Kuśnierczyk A, Hildrestrand GA, Graupner A, Andersen JM, Slupphaug G, Klungland A, Nilsen H, Bjørås M (2017)
   No cancer predisposition or increased spontaneous mutation frequencies in NEIL DNA glycosylases-deficient mice
   Sci Rep, 7 (1), 4384
   DOI 10.1038/s41598-017-04472-4, PubMed 28663564
9. Seifermann M, Ulges A, Bopp T, Melcea S, Schäfer A, Oka S, Nakabeppu Y, Klungland A, Niehrs C, Epe B (2017)
   Role of the DNA repair glycosylase OGG1 in the activation of murine splenocytes
   DNA Repair (Amst), 58, 13-20
   DOI 10.1016/j.dnarep.2017.08.005, PubMed 28843610
10. Tang C, Klukovich R, Peng H, Wang Z, Yu T, Zhang Y, Zheng H, Klungland A, Yan W (2017)
    ALKBH5-dependent m6A demethylation controls splicing and stability of long 3'-UTR mRNAs in male germ cells
    Proc Natl Acad Sci U S A, 115 (2), E325-E333
    DOI 10.1073/pnas.1717794115, PubMed 29279410
11. Aas A, Isakson P, Bindesbøll C, Alemu EA, Klungland A, Simonsen A (2017)
    Nucleocytoplasmic Shuttling of FTO Does Not Affect Starvation-Induced Autophagy
    PLoS One, 12 (3), e0168182
    DOI 10.1371/journal.pone.0168182, PubMed 28288181

Publications 2016

1. A Alemu E, He C, Klungland A (2016)
   ALKBHs-facilitated RNA modifications and de-modifications
   DNA Repair (Amst), 44, 87-91
   DOI 10.1016/j.dnarep.2016.05.026, PubMed 27237585
2. Dahl JA, Jung I, Aanes H, Greggains GD, Manaf A, Lerdrup M, Li G, Kuan S, Li B, Lee AY, Preissl S, Jermstad I, Haugen MH, Suganthan R, Bjørås M, Hansen K, Dalen KT, Fedorcsak P, Ren B, Klungland A (2016)
   Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition
   Nature, 537 (7621), 548-552
   DOI 10.1038/nature19360, PubMed 27626377
3. Klungland A, Dahl JA, Greggains G, Fedorcsak P, Filipczyk A (2016)
   Reversible RNA modifications in meiosis and pluripotency
   Nat Methods, 14 (1), 18-22
   DOI 10.1038/nmeth.4111, PubMed 28032624
4. Klungland A, Robertson AB (2016)
   Oxidized C5-methyl cytosine bases in DNA: 5-Hydroxymethylcytosine; 5-formylcytosine; and 5-carboxycytosine
   Free Radic Biol Med, 107, 62-68
   DOI 10.1016/j.freeradbiomed.2016.11.038, PubMed 27890639
5. Landfors M, Nakken S, Fusser M, Dahl JA, Klungland A, Fedorcsak P (2016)
   Sequencing of FTO and ALKBH5 in men undergoing infertility work-up identifies an infertility-associated variant and two missense mutations
   Fertil Steril, 105 (5), 1170-1179.e5
   DOI 10.1016/j.fertnstert.2016.01.002, PubMed 26820768
6. Lauritzen KH, Hasan-Olive MM, Regnell CE, Kleppa L, Scheibye-Knudsen M, Gjedde A, Klungland A, Bohr VA, Storm-Mathisen J, Bergersen LH (2016)
   A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain
   Neurobiol Aging, 48, 34-47
   DOI 10.1016/j.neurobiolaging.2016.08.005, PubMed 27639119
7. Lillenes MS, Rabano A, Støen M, Riaz T, Misaghian D, Møllersen L, Esbensen Y, Günther CC, Selnes P, Stenset VT, Fladby T, Tønjum T (2016)
   Altered DNA base excision repair profile in brain tissue and blood in Alzheimer's disease
   Mol Brain, 9 (1), 61
   DOI 10.1186/s13041-016-0237-z, PubMed 27234294
8. Liu F, Clark W, Luo G, Wang X, Fu Y, Wei J, Wang X, Hao Z, Dai Q, Zheng G, Ma H, Han D, Evans M, Klungland A, Pan T, He C (2016)
   ALKBH1-Mediated tRNA Demethylation Regulates Translation
   Cell, 167 (3), 816-828.e16
   DOI 10.1016/j.cell.2016.09.038, PubMed 27745969
9. Liu F, Clark W, Luo G, Wang X, Fu Y, Wei J, Wang X, Hao Z, Dai Q, Zheng G, Ma H, Han D, Evans M, Klungland A, Pan T, He C (2016)
   ALKBH1-Mediated tRNA Demethylation Regulates Translation
   Cell, 167 (7), 1897
   DOI 10.1016/j.cell.2016.11.045, PubMed 27984735
10. Møllersen L, Moldestad O, Rowe AD, Bjølgerud A, Holm I, Tveterås L, Klungland A, Retterstøl L (2016)
    Effects of Anthocyanins on CAG Repeat Instability and Behaviour in Huntington's Disease R6/1 Mice
    PLoS Curr, 8
    DOI 10.1371/currents.hd.58d04209ab6d5de0844db7ef5628ff67, PubMed 27540492
11. Ougland R, Jonson I, Moen MN, Nesse G, Asker G, Klungland A, Larsen E (2016)
    Role of ALKBH1 in the Core Transcriptional Network of Embryonic Stem Cells
    Cell Physiol Biochem, 38 (1), 173-84
    DOI 10.1159/000438619, PubMed 26765775
12. Rasmussen EMK, Vågbø CB, Münch D, Krokan HE, Klungland A, Amdam GV, Dahl JA (2016)
    DNA base modifications in honey bee and fruit fly genomes suggest an active demethylation machinery with species- and tissue-specific turnover rates
    Biochem Biophys Rep, 6, 9-15
    DOI 10.1016/j.bbrep.2016.02.011, PubMed 28955859
13. Skjærven KH, Jakt LM, Dahl JA, Espe M, Aanes H, Hamre K, Fernandes JM (2016)
    Parental vitamin deficiency affects the embryonic gene expression of immune-, lipid transport- and apolipoprotein genes
    Sci Rep, 6, 34535
    DOI 10.1038/srep34535, PubMed 27731423
14. Tekpli X, Urbanucci A, Hashim A, Vågbø CB, Lyle R, Kringen MK, Staff AC, Dybedal I, Mills IG, Klungland A, Staerk J (2016)
    Changes of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells
    Epigenetics Chromatin, 9, 21
    DOI 10.1186/s13072-016-0070-8, PubMed 27252783
15. Vander Zanden CM, Rowe RK, Broad AJ, Robertson AB, Ho PS (2016)
    Effect of Hydroxymethylcytosine on the Structure and Stability of Holliday Junctions
    Biochemistry, 55 (41), 5781-5789
    DOI 10.1021/acs.biochem.6b00801, PubMed 27653243
16. Vindedal GF, Thoren AE, Jensen V, Klungland A, Zhang Y, Holtzman MJ, Ottersen OP, Nagelhus EA (2016)
    Removal of aquaporin-4 from glial and ependymal membranes causes brain water accumulation
    Mol Cell Neurosci, 77, 47-52
    DOI 10.1016/j.mcn.2016.10.004, PubMed 27751903
17. Weber AR, Krawczyk C, Robertson AB, Kuśnierczyk A, Vågbø CB, Schuermann D, Klungland A, Schär P (2016)
    Biochemical reconstitution of TET1-TDG-BER-dependent active DNA demethylation reveals a highly coordinated mechanism
    Nat Commun, 7, 10806
    DOI 10.1038/ncomms10806, PubMed 26932196

Publications 2015

1. Bjørge MD, Hildrestrand GA, Scheffler K, Suganthan R, Rolseth V, Kuśnierczyk A, Rowe AD, Vågbø CB, Vetlesen S, Eide L, Slupphaug G, Nakabeppu Y, Bredy TW, Klungland A, Bjørås M (2015)
   Synergistic Actions of Ogg1 and Mutyh DNA Glycosylases Modulate Anxiety-like Behavior in Mice
   Cell Rep, 13 (12), 2671-8
   DOI 10.1016/j.celrep.2015.12.001, PubMed 26711335
2. Chymkowitch P, Nguéa AP, Aanes H, Koehler CJ, Thiede B, Lorenz S, Meza-Zepeda LA, Klungland A, Enserink JM (2015)
   Sumoylation of Rap1 mediates the recruitment of TFIID to promote transcription of ribosomal protein genes
   Genome Res, 25 (6), 897-906
   DOI 10.1101/gr.185793.114, PubMed 25800674
3. Dahl JA, Klungland A (2015)
   Micro chromatin immunoprecipitation (μChIP) from early mammalian embryos
   Methods Mol Biol, 1222, 227-45
   DOI 10.1007/978-1-4939-1594-1_17, PubMed 25287350
4. Fusser M, Kernstock S, Aileni VK, Egge-Jacobsen W, Falnes PØ, Klungland A (2015)
   Lysine Methylation of the Valosin-Containing Protein (VCP) Is Dispensable for Development and Survival of Mice
   PLoS One, 10 (11), e0141472
   DOI 10.1371/journal.pone.0141472, PubMed 26544960
5. Ke S, Alemu EA, Mertens C, Gantman EC, Fak JJ, Mele A, Haripal B, Zucker-Scharff I, Moore MJ, Park CY, Vågbø CB, Kusśnierczyk A, Klungland A, Darnell JE, Darnell RB (2015)
   A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation
   Genes Dev, 29 (19), 2037-53
   DOI 10.1101/gad.269415.115, PubMed 26404942
6. Klungland A, Yang YG (2015)
   Endogenous DNA Damage and Repair Enzymes: -A short summary of the scientific achievements of Tomas Lindahl, Nobel Laureate in Chemistry 2015
   Genomics Proteomics Bioinformatics, 14 (3), 122-125
   DOI 10.1016/j.gpb.2015.11.001, PubMed 26689322
7. Lauritzen KH, Kleppa L, Aronsen JM, Eide L, Carlsen H, Haugen ØP, Sjaastad I, Klungland A, Rasmussen LJ, Attramadal H, Storm-Mathisen J, Bergersen LH (2015)
   Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure
   Am J Physiol Heart Circ Physiol, 309 (3), H434-49
   DOI 10.1152/ajpheart.00253.2014, PubMed 26055793
8. Mi S, Klungland A, Yang YG (2015)
   Base-excision repair and beyond --A short summary attributed to scientific achievements of Tomas Lindahl, Nobel Prize Laureate in Chemistry 2015
   Sci China Life Sci, 59 (1), 89-92
   DOI 10.1007/s11427-015-4983-4, PubMed 26676642
9. Ougland R, Rognes T, Klungland A, Larsen E (2015)
   Non-homologous functions of the AlkB homologs
   J Mol Cell Biol, 7 (6), 494-504
   DOI 10.1093/jmcb/mjv029, PubMed 26003568

Publications 2014

1. Klungland A, Dahl JA (2014)
   Dynamic RNA modifications in disease
   Curr Opin Genet Dev, 26, 47-52
   DOI 10.1016/j.gde.2014.05.006, PubMed 25005745
2. Nilsen A, Fusser M, Greggains G, Fedorcsak P, Klungland A (2014)
   ALKBH4 depletion in mice leads to spermatogenic defects
   PLoS One, 9 (8), e105113
   DOI 10.1371/journal.pone.0105113, PubMed 25153837
3. Robertson AB, Dahl JA, Klungland A (2014)
   DNA metabolism: bases of DNA repair and regulation
   Nat Chem Biol, 10 (7), 487-8
   DOI 10.1038/nchembio.1553, PubMed 24937064
4. Robertson AB, Robertson J, Fusser M, Klungland A (2014)
   Endonuclease G preferentially cleaves 5-hydroxymethylcytosine-modified DNA creating a substrate for recombination
   Nucleic Acids Res, 42 (21), 13280-93
   DOI 10.1093/nar/gku1032, PubMed 25355512
5. Zdżalik D, Vågbø CB, Kirpekar F, Davydova E, Puścian A, Maciejewska AM, Krokan HE, Klungland A, Tudek B, van den Born E, Falnes PØ (2014)
   Protozoan ALKBH8 oxygenases display both DNA repair and tRNA modification activities
   PLoS One, 9 (6), e98729
   DOI 10.1371/journal.pone.0098729, PubMed 24914785

Publications 2013

1. Jonson I, Ougland R, Klungland A, Larsen E (2013)
   Oxidative stress causes DNA triplet expansion in Huntington's disease mouse embryonic stem cells
   Stem Cell Res, 11 (3), 1264-71
   DOI 10.1016/j.scr.2013.08.010, PubMed 24041806
2. Jonson I, Ougland R, Larsen E (2013)
   DNA repair mechanisms in Huntington's disease
   Mol Neurobiol, 47 (3), 1093-102
   DOI 10.1007/s12035-013-8409-7, PubMed 23361256
3. Li MM, Nilsen A, Shi Y, Fusser M, Ding YH, Fu Y, Liu B, Niu Y, Wu YS, Huang CM, Olofsson M, Jin KX, Lv Y, Xu XZ, He C, Dong MQ, Rendtlew Danielsen JM, Klungland A, Yang YG (2013)
   ALKBH4-dependent demethylation of actin regulates actomyosin dynamics
   Nat Commun, 4, 1832
   DOI 10.1038/ncomms2863, PubMed 23673617
4. Malatesta M, Steinhauer C, Mohammad F, Pandey DP, Squatrito M, Helin K (2013)
   Histone acetyltransferase PCAF is required for Hedgehog-Gli-dependent transcription and cancer cell proliferation
   Cancer Res, 73 (20), 6323-33
   DOI 10.1158/0008-5472.CAN-12-4660, PubMed 23943798
5. Solberg A, Robertson AB, Aronsen JM, Rognmo Ø, Sjaastad I, Wisløff U, Klungland A (2013)
   Deletion of mouse Alkbh7 leads to obesity
   J Mol Cell Biol, 5 (3), 194-203
   DOI 10.1093/jmcb/mjt012, PubMed 23572141
6. Zheng G, Dahl JA, Niu Y, Fu Y, Klungland A, Yang YG, He C (2013)
   Sprouts of RNA epigenetics: the discovery of mammalian RNA demethylases
   RNA Biol, 10 (6), 915-8
   DOI 10.4161/rna.24711, PubMed 23619745

Publications 2012

1. Calvo JA, Meira LB, Lee CY, Moroski-Erkul CA, Abolhassani N, Taghizadeh K, Eichinger LW, Muthupalani S, Nordstrand LM, Klungland A, Samson LD (2012)
   DNA repair is indispensable for survival after acute inflammation
   J Clin Invest, 122 (7), 2680-9
   DOI 10.1172/JCI63338, PubMed 22684101
2. Kleppa L, Mari PO, Larsen E, Lien GF, Godon C, Theil AF, Nesse GJ, Wiksen H, Vermeulen W, Giglia-Mari G, Klungland A (2012)
   Kinetics of endogenous mouse FEN1 in base excision repair
   Nucleic Acids Res, 40 (18), 9044-59
   DOI 10.1093/nar/gks673, PubMed 22810208
3. Møllersen L, Rowe AD, Illuzzi JL, Hildrestrand GA, Gerhold KJ, Tveterås L, Bjølgerud A, Wilson DM, Bjørås M, Klungland A (2012)
   Neil1 is a genetic modifier of somatic and germline CAG trinucleotide repeat instability in R6/1 mice
   Hum Mol Genet, 21 (22), 4939-47
   DOI 10.1093/hmg/dds337, PubMed 22914735

Publications 2011

1. Echeverría PC, Forafonov F, Pandey DP, Mühlebach G, Picard D (2011)
   Detection of changes in gene regulatory patterns, elicited by perturbations of the Hsp90 molecular chaperone complex, by visualizing multiple experiments with an animation
   BioData Min, 4 (1), 15
   DOI 10.1186/1756-0381-4-15, PubMed 21672238
2. Moen MN, Knævelsrud I, Haugland GT, Grøsvik K, Birkeland NK, Klungland A, Bjelland S (2011)
   Uracil-DNA glycosylase of Thermoplasma acidophilum directs long-patch base excision repair, which is promoted by deoxynucleoside triphosphates and ATP/ADP, into short-patch repair
   J Bacteriol, 193 (17), 4495-508
   DOI 10.1128/JB.00233-11, PubMed 21665970
3. Robertson AB, Dahl JA, Vågbø CB, Tripathi P, Krokan HE, Klungland A (2011)
   A novel method for the efficient and selective identification of 5-hydroxymethylcytosine in genomic DNA
   Nucleic Acids Res, 39 (8), e55
   DOI 10.1093/nar/gkr051, PubMed 21300643
4. Robertson J, Robertson AB, Klungland A (2011)
   The presence of 5-hydroxymethylcytosine at the gene promoter and not in the gene body negatively regulates gene expression
   Biochem Biophys Res Commun, 411 (1), 40-3
   DOI 10.1016/j.bbrc.2011.06.077, PubMed 21703242
5. Strømme P, Dobrenis K, Sillitoe RV, Gulinello M, Ali NF, Davidson C, Micsenyi MC, Stephney G, Ellevog L, Klungland A, Walkley SU (2011)
   X-linked Angelman-like syndrome caused by Slc9a6 knockout in mice exhibits evidence of endosomal-lysosomal dysfunction
   Brain, 134 (Pt 11), 3369-83
   DOI 10.1093/brain/awr250, PubMed 21964919

Publications 2010

1. Knævelsrud I, Moen MN, Grøsvik K, Haugland GT, Birkeland NK, Klungland A, Leiros I, Bjelland S (2010)
   The hyperthermophilic euryarchaeon Archaeoglobus fulgidus repairs uracil by single-nucleotide replacement
   J Bacteriol, 192 (21), 5755-66
   DOI 10.1128/JB.00135-10, PubMed 20453094
2. Songe-Møller L, van den Born E, Leihne V, Vågbø CB, Kristoffersen T, Krokan HE, Kirpekar F, Falnes PØ, Klungland A (2010)
   Mammalian ALKBH8 possesses tRNA methyltransferase activity required for the biogenesis of multiple wobble uridine modifications implicated in translational decoding
   Mol Cell Biol, 30 (7), 1814-27
   DOI 10.1128/MCB.01602-09, PubMed 20123966

Publications 2009

1. Robertson AB, Klungland A, Rognes T, Leiros I (2009)
   DNA repair in mammalian cells: Base excision repair: the long and short of it
   Cell Mol Life Sci, 66 (6), 981-93
   DOI 10.1007/s00018-009-8736-z, PubMed 19153658

Publications 2008

1. Albanito L, Sisci D, Aquila S, Brunelli E, Vivacqua A, Madeo A, Lappano R, Pandey DP, Picard D, Mauro L, Andò S, Maggiolini M (2008)
   Epidermal growth factor induces G protein-coupled receptor 30 expression in estrogen receptor-negative breast cancer cells
   Endocrinology, 149 (8), 3799-808
   DOI 10.1210/en.2008-0117, PubMed 18467441
2. Jørgensen MG, Pandey DP, Jaskolska M, Gerdes K (2008)
   HicA of Escherichia coli defines a novel family of translation-independent mRNA interferases in bacteria and archaea
   J Bacteriol, 191 (4), 1191-9
   DOI 10.1128/JB.01013-08, PubMed 19060138
3. Larsen E, Kleppa L, Meza TJ, Meza-Zepeda LA, Rada C, Castellanos CG, Lien GF, Nesse GJ, Neuberger MS, Laerdahl JK, William Doughty R, Klungland A (2008)
   Early-onset lymphoma and extensive embryonic apoptosis in two domain-specific Fen1 mice mutants
   Cancer Res, 68 (12), 4571-9
   DOI 10.1158/0008-5472.CAN-08-0168, PubMed 18559501

Publications 2007

1. Klungland A, Andersson KB (2007)
   [Nobel Prize for genetic modification]
   Tidsskr Nor Laegeforen, 127 (23), 3054
   PubMed 18049491
2. Kovtun IV, Liu Y, Bjoras M, Klungland A, Wilson SH, McMurray CT (2007)
   OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells
   Nature, 447 (7143), 447-52
   DOI 10.1038/nature05778, PubMed 17450122
3. Larsen E, Meza TJ, Kleppa L, Klungland A (2007)
   Organ and cell specificity of base excision repair mutants in mice
   Mutat Res, 614 (1-2), 56-68
   DOI 10.1016/j.mrfmmm.2006.01.023, PubMed 16765995
4. Leiros I, Nabong MP, Grøsvik K, Ringvoll J, Haugland GT, Uldal L, Reite K, Olsbu IK, Knaevelsrud I, Moe E, Andersen OA, Birkeland NK, Ruoff P, Klungland A, Bjelland S (2007)
   Structural basis for enzymatic excision of N1-methyladenine and N3-methylcytosine from DNA
   EMBO J, 26 (8), 2206-17
   DOI 10.1038/sj.emboj.7601662, PubMed 17396151
5. Nordstrand LM, Ringvoll J, Larsen E, Klungland A (2007)
   Genome instability and DNA damage accumulation in gene-targeted mice
   Neuroscience, 145 (4), 1309-17
   DOI 10.1016/j.neuroscience.2006.10.059, PubMed 17218062
6. Ringvoll J, Uldal L, Roed MA, Reite K, Baynton K, Klungland A, Eide L (2007)
   Mutations in the RAD27 and SGS1 genes differentially affect the chronological and replicative lifespan of yeast cells growing on glucose and glycerol
   FEMS Yeast Res, 7 (6), 848-59
   DOI 10.1111/j.1567-1364.2007.00248.x, PubMed 17506834
7. Risom L, Dybdahl M, Møller P, Wallin H, Haug T, Vogel U, Klungland A, Loft S (2007)
   Repeated inhalations of diesel exhaust particles and oxidatively damaged DNA in young oxoguanine DNA glycosylase (OGG1) deficient mice
   Free Radic Res, 41 (2), 172-81
   DOI 10.1080/10715760601024122, PubMed 17364943
8. Trapp C, Reite K, Klungland A, Epe B (2007)
   Deficiency of the Cockayne syndrome B (CSB) gene aggravates the genomic instability caused by endogenous oxidative DNA base damage in mice
   Oncogene, 26 (27), 4044-8
   DOI 10.1038/sj.onc.1210167, PubMed 17213818

Publications 2006

1. Falnes PØ, Klungland A, Alseth I (2006)
   Repair of methyl lesions in DNA and RNA by oxidative demethylation
   Neuroscience, 145 (4), 1222-32
   DOI 10.1016/j.neuroscience.2006.11.018, PubMed 17175108
2. Faridani OR, Nikravesh A, Pandey DP, Gerdes K, Good L (2006)
   Competitive inhibition of natural antisense Sok-RNA interactions activates Hok-mediated cell killing in Escherichia coli
   Nucleic Acids Res, 34 (20), 5915-22
   DOI 10.1093/nar/gkl750, PubMed 17065468
3. Herszfeld D, Wolvetang E, Langton-Bunker E, Chung TL, Filipczyk AA, Houssami S, Jamshidi P, Koh K, Laslett AL, Michalska A, Nguyen L, Reubinoff BE, Tellis I, Auerbach JM, Ording CJ, Looijenga LH, Pera MF (2006)
   CD30 is a survival factor and a biomarker for transformed human pluripotent stem cells
   Nat Biotechnol, 24 (3), 351-7
   DOI 10.1038/nbt1197, PubMed 16501577
4. Kleppa L, Kanavin ØJ, Klungland A, Strømme P (2006)
   A novel splice site mutation in the Cockayne syndrome group A gene in two siblings with Cockayne syndrome
   Neuroscience, 145 (4), 1397-406
   DOI 10.1016/j.neuroscience.2006.09.025, PubMed 17084038
5. Larsen E, Reite K, Nesse G, Gran C, Seeberg E, Klungland A (2006)
   Repair and mutagenesis at oxidized DNA lesions in the developing brain of wild-type and Ogg1-/- mice
   Oncogene, 25 (17), 2425-32
   DOI 10.1038/sj.onc.1209284, PubMed 16369492
6. Ringvoll J, Nordstrand LM, Vågbø CB, Talstad V, Reite K, Aas PA, Lauritzen KH, Liabakk NB, Bjørk A, Doughty RW, Falnes PØ, Krokan HE, Klungland A (2006)
   Repair deficient mice reveal mABH2 as the primary oxidative demethylase for repairing 1meA and 3meC lesions in DNA
   EMBO J, 25 (10), 2189-98
   DOI 10.1038/sj.emboj.7601109, PubMed 16642038
7. Touati E, Michel V, Thiberge JM, Avé P, Huerre M, Bourgade F, Klungland A, Labigne A (2006)
   Deficiency in OGG1 protects against inflammation and mutagenic effects associated with H. pylori infection in mouse
   Helicobacter, 11 (5), 494-505
   DOI 10.1111/j.1523-5378.2006.00442.x, PubMed 16961812

Publications 2005

1. Holen T, Moe SE, Sørbø JG, Meza TJ, Ottersen OP, Klungland A (2005)
   Tolerated wobble mutations in siRNAs decrease specificity, but can enhance activity in vivo
   Nucleic Acids Res, 33 (15), 4704-10
   DOI 10.1093/nar/gki785, PubMed 16113241
2. Rozalski R, Siomek A, Gackowski D, Foksinski M, Gran C, Klungland A, Olinski R (2005)
   Substantial decrease of urinary 8-oxo-7,8-dihydroguanine, a product of the base excision repair pathway, in DNA glycosylase defective mice
   Int J Biochem Cell Biol, 37 (6), 1331-6
   DOI 10.1016/j.biocel.2005.01.001, PubMed 15778095

Publications 2004

1. Foksinski M, Rozalski R, Guz J, Ruszkowska B, Sztukowska P, Piwowarski M, Klungland A, Olinski R (2004)
   Urinary excretion of DNA repair products correlates with metabolic rates as well as with maximum life spans of different mammalian species
   Free Radic Biol Med, 37 (9), 1449-54
   DOI 10.1016/j.freeradbiomed.2004.07.014, PubMed 15454284
2. Larsen E, Kwon K, Coin F, Egly JM, Klungland A (2004)
   Transcription activities at 8-oxoG lesions in DNA
   DNA Repair (Amst), 3 (11), 1457-68
   DOI 10.1016/j.dnarep.2004.06.008, PubMed 15380101
3. Rozalski R, Siomek A, Gackowski D, Foksinski M, Gran C, Klungland A, Olinski R (2004)
   Diet is not responsible for the presence of several oxidatively damaged DNA lesions in mouse urine
   Free Radic Res, 38 (11), 1201-5
   DOI 10.1080/10715760400017350, PubMed 15621697

Publications 2003

1. Dantzer F, Bjørås M, Luna L, Klungland A, Seeberg E (2003)
   Comparative analysis of 8-oxoG:C, 8-oxoG:A, A:C and C:C DNA repair in extracts from wild type or 8-oxoG DNA glycosylase deficient mammalian and bacterial cells
   DNA Repair (Amst), 2 (6), 707-18
   DOI 10.1016/s1568-7864(03)00041-7, PubMed 12767349
2. Larsen E, Gran C, Saether BE, Seeberg E, Klungland A (2003)
   Proliferation failure and gamma radiation sensitivity of Fen1 null mutant mice at the blastocyst stage
   Mol Cell Biol, 23 (15), 5346-53
   DOI 10.1128/MCB.23.15.5346-5353.2003, PubMed 12861020
3. Moe A, Ringvoll J, Nordstrand LM, Eide L, Bjørås M, Seeberg E, Rognes T, Klungland A (2003)
   Incision at hypoxanthine residues in DNA by a mammalian homologue of the Escherichia coli antimutator enzyme endonuclease V
   Nucleic Acids Res, 31 (14), 3893-900
   DOI 10.1093/nar/gkg472, PubMed 12853604
4. Rogers PA, Eide L, Klungland A, Ding H (2003)
   Reversible inactivation of E. coli endonuclease III via modification of its [4Fe-4S] cluster by nitric oxide
   DNA Repair (Amst), 2 (7), 809-17
   DOI 10.1016/s1568-7864(03)00065-x, PubMed 12826281
5. Seeberg E, Klungland A (2003)
   Better late than never for repair of miscoding lesions within a transcribed template
   Mol Cell, 12 (4), 799-800
   DOI 10.1016/s1097-2765(03)00403-9, PubMed 14580331

Publications 2002

1. Birkeland NK, Anensen H, Knaevelsrud I, Kristoffersen W, Bjørås M, Robb FT, Klungland A, Bjelland S (2002)
   Methylpurine DNA glycosylase of the hyperthermophilic archaeon Archaeoglobus fulgidus
   Biochemistry, 41 (42), 12697-705
   DOI 10.1021/bi020334w, PubMed 12379112
2. Osterod M, Larsen E, Le Page F, Hengstler JG, Van Der Horst GT, Boiteux S, Klungland A, Epe B (2002)
   A global DNA repair mechanism involving the Cockayne syndrome B (CSB) gene product can prevent the in vivo accumulation of endogenous oxidative DNA base damage
   Oncogene, 21 (54), 8232-9
   DOI 10.1038/sj.onc.1206027, PubMed 12447686

Publications 2001

1. de Souza-Pinto NC, Eide L, Hogue BA, Thybo T, Stevnsner T, Seeberg E, Klungland A, Bohr VA (2001)
   Repair of 8-oxodeoxyguanosine lesions in mitochondrial dna depends on the oxoguanine dna glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial dna of OGG1-defective mice
   Cancer Res, 61 (14), 5378-81
   PubMed 11454679
2. Klungland A (2001)
   [Life without DNA repair]
   Tidsskr Nor Laegeforen, 121 (1), 41-9
   PubMed 12013614
3. Klungland A, Paulsen R, Rolseth V, Yamada Y, Ueno Y, Wiik P, Matsuda A, Seeberg E, Bjelland S (2001)
   5-Formyluracil and its nucleoside derivatives confer toxicity and mutagenicity to mammalian cells by interfering with normal RNA and DNA metabolism
   Toxicol Lett, 119 (1), 71-8
   DOI 10.1016/s0378-4274(00)00308-8, PubMed 11275423
4. Knaevelsrud I, Ruoff P, Anensen H, Klungland A, Bjelland S, Birkeland NK (2001)
   Excision of uracil from DNA by the hyperthermophilic Afung protein is dependent on the opposite base and stimulated by heat-induced transition to a more open structure
   Mutat Res, 487 (3-4), 173-90
   DOI 10.1016/s0921-8777(01)00115-x, PubMed 11738943

Publications 2000

1. Le Page F, Klungland A, Barnes DE, Sarasin A, Boiteux S (2000)
   Transcription coupled repair of 8-oxoguanine in murine cells: the ogg1 protein is required for repair in nontranscribed sequences but not in transcribed sequences
   Proc Natl Acad Sci U S A, 97 (15), 8397-402
   DOI 10.1073/pnas.140137297, PubMed 10890888
2. Seeberg E, Luna L, Morland I, Eide L, Johnsen B, Larsen E, Alseth I, Dantzer F, Baynton K, Aamodt R, Kristiansen KI, Rognes T, Klungland A, Bjørås M (2000)
   Base removers and strand scissors: different strategies employed in base excision and strand incision at modified base residues in DNA
   Cold Spring Harb Symp Quant Biol, 65, 135-42
   DOI 10.1101/sqb.2000.65.135, PubMed 12760028

Publications 1997

1. Lindahl T, Barnes DE, Klungland A, Mackenney VJ, Schär P (1997)
   Repair and processing events at DNA ends
   Ciba Found Symp, 211, 198-205; discussion 205-8
   DOI 10.1002/9780470515433.ch13, PubMed 9524759
2. Roldán-Arjona T, Wei YF, Carter KC, Klungland A, Anselmino C, Wang RP, Augustus M, Lindahl T (1997)
   Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylase
   Proc Natl Acad Sci U S A, 94 (15), 8016-20
   DOI 10.1073/pnas.94.15.8016, PubMed 9223306

Publications 1996

1. Kubota Y, Nash RA, Klungland A, Schär P, Barnes DE, Lindahl T (1996)
   Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein
   EMBO J, 15 (23), 6662-70
   PubMed 8978692

Publications 1995

1. Bjørås M, Klungland A, Johansen RF, Seeberg E (1995)
   Purification and properties of the alkylation repair DNA glycosylase encoded the MAG gene from Saccharomyces cerevisiae
   Biochemistry, 34 (14), 4577-82
   DOI 10.1021/bi00014a010, PubMed 7718559
2. Lindahl T, Satoh MS, Poirier GG, Klungland A (1995)
   Post-translational modification of poly(ADP-ribose) polymerase induced by DNA strand breaks
   Trends Biochem Sci, 20 (10), 405-11
   DOI 10.1016/s0968-0004(00)89089-1, PubMed 8533153