Bernward Zeller
- Consultant; PhD
Publications 2024
Corrigendum: Cancer data quality and harmonization in Europe: The experience of the BENCHISTA Project - International Benchmarking of Childhood Cancer Survival by Stage
Front Oncol, 14, 1397101
DOI 10.3389/fonc.2024.1397101, PubMed 38606092
Mitoxantrone Versus Liposomal Daunorubicin in Induction of Pediatric AML With Risk Stratification Based on Flow Cytometry Measurement of Residual Disease
J Clin Oncol, 42 (18), 2174-2185
DOI 10.1200/JCO.23.01841, PubMed 38603646
Management of hyperleukocytosis in pediatric acute myeloid leukemia using immediate chemotherapy without leukapheresis: results from the NOPHO-DBH AML 2012 protocol
Haematologica, 109 (9), 2873-2883
DOI 10.3324/haematol.2024.285285, PubMed 38721737
Characterization of Pediatric Acute Myeloid Leukemia With t(7;12)(q36;p13)
Genes Chromosomes Cancer, 63 (11), e70003
DOI 10.1002/gcc.70003, PubMed 39508359
Publications 2023
Hypodiploidy has unfavorable impact on survival in pediatric acute myeloid leukemia: an I-BFM Study Group collaboration
Blood Adv, 7 (6), 1045-1055
DOI 10.1182/bloodadvances.2022008251, PubMed 36332007
Characteristics and outcome of primary resistant disease in paediatric acute myeloid leukaemia
Br J Haematol, 201 (4), 757-765
DOI 10.1111/bjh.18685, PubMed 36762836
Cancer data quality and harmonization in Europe: the experience of the BENCHISTA Project - international benchmarking of childhood cancer survival by stage
Front Oncol, 13, 1232451
DOI 10.3389/fonc.2023.1232451, PubMed 37675230
Publications 2022
Supportive care in pediatric acute myeloid leukemia:Expert-based recommendations of the NOPHO-DB-SHIP consortium
Expert Rev Anticancer Ther, 22 (11), 1183-1196
DOI 10.1080/14737140.2022.2131544, PubMed 36191604
Proteogenomic analysis of acute myeloid leukemia associates relapsed disease with reprogrammed energy metabolism both in adults and children
Leukemia, 37 (3), 550-559
DOI 10.1038/s41375-022-01796-7, PubMed 36572751
Transcriptomic analysis reveals proinflammatory signatures associated with acute myeloid leukemia progression
Blood Adv, 6 (1), 152-164
DOI 10.1182/bloodadvances.2021004962, PubMed 34619772
[A warm reunion in Münster! : Review of the 105th DGP Annual Conference in Münster]
Pathologie (Heidelb), 43 (Suppl 1), 1-2
DOI 10.1007/s00292-022-01156-3, PubMed 36525053
Publications 2021
Abdominal Complications During Treatment for Pediatric Acute Myeloid Leukemia
J Pediatr Hematol Oncol, 44 (5), 220-229
DOI 10.1097/MPH.0000000000002281, PubMed 34387627
Response to mitogen-activated protein kinase inhibition of neurodegeneration in Langerhans cell histiocytosis monitored by cerebrospinal fluid neurofilament light as a biomarker: a pilot study
Br J Haematol, 196 (1), 248-254
DOI 10.1111/bjh.17781, PubMed 34435355
DNA Methylation Signatures Predict Cytogenetic Subtype and Outcome in Pediatric Acute Myeloid Leukemia (AML)
Genes (Basel), 12 (6)
DOI 10.3390/genes12060895, PubMed 34200630
Therapy-induced Deletion in 11q23 Leading to Fusion of KMT2A With ARHGEF12 and Development of B Lineage Acute Lymphoplastic Leukemia in a Child Treated for Acute Myeloid Leukemia Caused by t(9;11)(p21;q23)/KMT2A-MLLT3
Cancer Genomics Proteomics, 18 (1), 67-81
DOI 10.21873/cgp.20242, PubMed 33419897
Genomic characterization of relapsed acute myeloid leukemia reveals novel putative therapeutic targets
Blood Adv, 5 (3), 900-912
DOI 10.1182/bloodadvances.2020003709, PubMed 33560403
Therapeutic implications of improved molecular diagnostics for rare CNS embryonal tumor entities: results of an international, retrospective study
Neuro Oncol, 23 (9), 1597-1611
DOI 10.1093/neuonc/noab136, PubMed 34077956
Publications 2020
TYRO3 Truncation Resulting From a t(10;15)(p11;q15) Chromosomal Translocation in Pediatric Acute Myeloid Leukemia
Anticancer Res, 40 (11), 6115-6121
DOI 10.21873/anticanres.14632, PubMed 33109549
Measurable residual disease assessment by qPCR in peripheral blood is an informative tool for disease surveillance in childhood acute myeloid leukaemia
Br J Haematol, 190 (2), 198-208
DOI 10.1111/bjh.16560, PubMed 32175599
[DGP2020 goes digital-the conversion of the 104th Annual Meeting of the DGP into a digital congress in two months]
Pathologe, 41 (Suppl 2), 61-65
DOI 10.1007/s00292-020-00869-7, PubMed 33296021
Acute lymphoblastic leukemia and down syndrome: 6-mercaptopurine and methotrexate metabolites during maintenance therapy
Leukemia, 35 (3), 863-866
DOI 10.1038/s41375-020-0946-2, PubMed 32623444
Publications 2019
Use of granulocyte colony-stimulating factor and risk of relapse in pediatric patients treated for acute myeloid leukemia according to NOPHO-AML 2004 and DB AML-01
Pediatr Blood Cancer, 66 (6), e27701
DOI 10.1002/pbc.27701, PubMed 30848067
Associations between pretherapeutic body mass index, outcome, and cytogenetic abnormalities in pediatric acute myeloid leukemia
Cancer Med, 8 (15), 6634-6643
DOI 10.1002/cam4.2554, PubMed 31532076
Measurable residual disease monitoring using Wilms tumor gene 1 expression in childhood acute myeloid leukemia based on child-specific reference values
Pediatr Blood Cancer, 66 (6), e27671
DOI 10.1002/pbc.27671, PubMed 30900388
Children treated for medulloblastoma and supratentorial primitive neuroectodermal tumor in Norway from 1974 through 2013: Unexplainable regional differences in survival
Pediatr Blood Cancer, 66 (10), e27910
DOI 10.1002/pbc.27910, PubMed 31264356
Publications 2018
Complex and monosomal karyotype are distinct cytogenetic entities with an adverse prognostic impact in paediatric acute myeloid leukaemia. A NOPHO-DBH-AML study
Br J Haematol, 183 (4), 618-628
DOI 10.1111/bjh.15587, PubMed 30406946
Acute myeloid leukemia (AML) with t(7;12)(q36;p13) is associated with infancy and trisomy 19: Data from Nordic Society for Pediatric Hematology and Oncology (NOPHO-AML) and review of the literature
Genes Chromosomes Cancer, 57 (7), 359-365
DOI 10.1002/gcc.22538, PubMed 29569294
MECOM-associated syndrome: a heterogeneous inherited bone marrow failure syndrome with amegakaryocytic thrombocytopenia
Blood Adv, 2 (6), 586-596
DOI 10.1182/bloodadvances.2018016501, PubMed 29540340
Associations between neutrophil recovery time, infections and relapse in pediatric acute myeloid leukemia
Pediatr Blood Cancer, 65 (9), e27231
DOI 10.1002/pbc.27231, PubMed 29781563
[Some thoughts in the wake of a fatal medication error]
Tidsskr Nor Laegeforen, 138 (4)
DOI 10.4045/tidsskr.18.0031, PubMed 29460591
[Not Available]
Tidsskr Nor Laegeforen, 138 (7)
DOI 10.4045/tidsskr.18.0234, PubMed 29663759
Some thoughts in the wake of a fatal error in medication
Tidsskr. Nor. Laegeforen., 138 (4), 325
Publications 2017
Outcome after intensive reinduction therapy and allogeneic stem cell transplant in paediatric relapsed acute myeloid leukaemia
Br J Haematol, 178 (4), 592-602
DOI 10.1111/bjh.14720, PubMed 28439893
Extramedullary leukemia in children with acute myeloid leukemia: A population-based cohort study from the Nordic Society of Pediatric Hematology and Oncology (NOPHO)
Pediatr Blood Cancer, 64 (12)
DOI 10.1002/pbc.26520, PubMed 28333413
Hyperleucocytosis in paediatric acute myeloid leukaemia - the challenge of white blood cell counts above 200 × 109 /l. The NOPHO experience 1984-2014
Br J Haematol, 178 (3), 448-456
DOI 10.1111/bjh.14692, PubMed 28542715
Publications 2016
Trisomy 8 in pediatric acute myeloid leukemia: A NOPHO-AML study
Genes Chromosomes Cancer, 55 (9), 719-26
DOI 10.1002/gcc.22373, PubMed 27153159
Effect of age and body weight on toxicity and survival in pediatric acute myeloid leukemia: results from NOPHO-AML 2004
Haematologica, 101 (11), 1359-1367
DOI 10.3324/haematol.2016.146175, PubMed 27470605
Rare MLL-ELL fusion transcripts in childhood acute myeloid leukemia-association with young age and myeloid sarcomas?
Exp Hematol Oncol, 5, 8
DOI 10.1186/s40164-016-0037-2, PubMed 26949571
RUNX1 truncation resulting from a cryptic and novel t(6;21)(q25;q22) chromosome translocation in acute myeloid leukemia: A case report
Oncol Rep, 36 (5), 2481-2488
DOI 10.3892/or.2016.5119, PubMed 27667292
Pediatrics
Tidsskr. Nor. Laegeforen., 136 (17), 1471
DOI 10.4045/tidsskr.16.0600
[Child cancer is different]
Tidsskr Nor Laegeforen, 136 (17), 1464-6
DOI 10.4045/tidsskr.16.0336, PubMed 27686208
Publications 2015
Neurocognitive Outcome in Very Long-Term Survivors of Childhood Acute Lymphoblastic Leukemia After Treatment with Chemotherapy Only
Pediatr Blood Cancer, 63 (1), 133-8
DOI 10.1002/pbc.25690, PubMed 26312396
Clinical Impact of Additional Cytogenetic Aberrations, cKIT and RAS Mutations, and Treatment Elements in Pediatric t(8;21)-AML: Results From an International Retrospective Study by the International Berlin-Frankfurt-Münster Study Group
J Clin Oncol, 33 (36), 4247-58
DOI 10.1200/JCO.2015.61.1947, PubMed 26573082
Myeloid leukemia of Down syndrome: relation to parvovirus B19 infection and wilms tumor gene (WT1) expression
J Pediatr Hematol Oncol, 37 (1), e67-8
DOI 10.1097/MPH.0000000000000093, PubMed 24390447
The applicability of the WHO classification in paediatric AML. A NOPHO-AML study
Br J Haematol, 169 (6), 859-67
DOI 10.1111/bjh.13366, PubMed 25819835
Cortical surface area and thickness in adult survivors of pediatric acute lymphoblastic leukemia
Pediatr Blood Cancer, 62 (6), 1027-34
DOI 10.1002/pbc.25386, PubMed 25597852
Acute Myeloid Leukemia in Adolescents and Young Adults Treated in Pediatric and Adult Departments in the Nordic Countries
Pediatr Blood Cancer, 63 (1), 83-92
DOI 10.1002/pbc.25713, PubMed 26281822
Life after child cancer
Tidsskr. Nor. Laegeforen., 135 (7), 678
DOI 10.4045/tidsskr.15.0058
Publications 2014
Asparaginase-associated pancreatitis in children with acute lymphoblastic leukaemia in the NOPHO ALL2008 protocol
Br J Haematol, 165 (1), 126-33
DOI 10.1111/bjh.12733, PubMed 24428625
Ploidy and clinical characteristics of childhood acute myeloid leukemia: A NOPHO-AML study
Genes Chromosomes Cancer, 53 (8), 667-75
DOI 10.1002/gcc.22177, PubMed 24753324
Chronic fatigue in long-term survivors of childhood lymphomas and leukemia: persistence and associated clinical factors
J Pediatr Hematol Oncol, 36 (6), 438-44
DOI 10.1097/MPH.0000000000000051, PubMed 24276036
Publications 2013
High Prevalence of Chronic Fatigue in Adult Long-Term Survivors of Acute Lymphoblastic Leukemia and Lymphoma During Childhood and Adolescence
J. Adolesc. Young Adult Oncol., 2 (1), 2-9
DOI 10.1089/jayao.2012.0015
Serum cytokines and chronic fatigue in adults surviving after childhood leukemia and lymphoma
Brain Behav Immun, 30, 80-7
DOI 10.1016/j.bbi.2013.01.006, PubMed 23333795
Cryptic FUS-ERG fusion identified by RNA-sequencing in childhood acute myeloid leukemia
Oncol Rep, 30 (6), 2587-92
DOI 10.3892/or.2013.2751, PubMed 24068373
Fusion of ZMYND8 and RELA genes in acute erythroid leukemia
PLoS One, 8 (5), e63663
DOI 10.1371/journal.pone.0063663, PubMed 23667654
Outcome of poor response paediatric AML using early SCT
Eur J Haematol, 90 (3), 187-94
DOI 10.1111/ejh.12051, PubMed 23215948
Chronic fatigue in adult survivors of childhood cancer: associated symptoms, neuroendocrine markers, and autonomic cardiovascular responses
Psychosomatics, 55 (6), 621-9
DOI 10.1016/j.psym.2013.12.005, PubMed 24656688
Reduced neuroanatomic volumes in long-term survivors of childhood acute lymphoblastic leukemia
J Clin Oncol, 31 (17), 2078-85
DOI 10.1200/JCO.2012.47.4031, PubMed 23589559
Response to A.A.M. van der Veldt et al
J Clin Oncol, 32 (8), 852-3
DOI 10.1200/JCO.2013.52.5725, PubMed 24220558
Publications 2012
Physicians compliance during maintenance therapy in children with Down syndrome and acute lymphoblastic leukemia
Leukemia, 27 (4), 866-70
DOI 10.1038/leu.2012.325, PubMed 23138181
Gemtuzumab ozogamicin as postconsolidation therapy does not prevent relapse in children with AML: results from NOPHO-AML 2004
Blood, 120 (5), 978-84
DOI 10.1182/blood-2012-03-416701, PubMed 22730539
High-throughput sequencing identifies an NFIA/CBFA2T3 fusion gene in acute erythroid leukemia with t(1;16)(p31;q24)
Leukemia, 27 (4), 980-2
DOI 10.1038/leu.2012.266, PubMed 23032695
Duration and morbidity of chronic immune thrombocytopenic purpura in children: five-year follow-up of a Nordic cohort
Acta Paediatr, 101 (7), 761-6
DOI 10.1111/j.1651-2227.2012.02671.x, PubMed 22429281
Patient knowledge of late effects of acute lymphoblastic leukaemia
Tidsskr Nor Laegeforen, 132 (18), 2052-5
DOI 10.4045/tidsskr.12.0153, PubMed 23038194
High ERG gene expression is an unfavorable prognostic marker in pediatric acute myeloid leukemia Response
Blood, 119 (4), 1087-1088
DOI 10.1182/blood-2011-12-393355
Publications 2011
Translocation t(1;16)(p31;q24) rearranging CBFA2T3 is specific for acute erythroid leukemia
Leukemia, 25 (9), 1510-2
DOI 10.1038/leu.2011.100, PubMed 21606959
Identification of the TAF15-ZNF384 fusion gene in two new cases of acute lymphoblastic leukemia with a t(12;17)(p13;q12)
Cancer Genet, 204 (3), 147-52
DOI 10.1016/j.cancergen.2011.01.003, PubMed 21504714
Presence of FLT3-ITD and high BAALC expression are independent prognostic markers in childhood acute myeloid leukemia
Blood, 118 (22), 5905-13
DOI 10.1182/blood-2011-05-353185, PubMed 21967978
Immunological thrombo-cytopenia in children
Tidsskr Nor Laegeforen, 131 (1), 13
DOI 10.4045/tidsskr.10.1279, PubMed 21233875
H1N1 infection in children with haematological and oncological diseases in Norway
Acta Paediatr, 100 (8), 1134-7
DOI 10.1111/j.1651-2227.2011.02244.x, PubMed 21362035
Publications 2010
Response-guided induction therapy in pediatric acute myeloid leukemia with excellent remission rate
J Clin Oncol, 29 (3), 310-5
DOI 10.1200/JCO.2010.30.6829, PubMed 21149663
Publications 2009
Poor treatment compliance in children with down syndrome and acute lymphoblastic leukemia
J Pediatr Hematol Oncol, 31 (1), 79-80
DOI 10.1097/MPH.0b013e31818b37a9, PubMed 19125098
Publications 2007
Improved outcome after relapse in children with acute myeloid leukaemia
Br J Haematol, 136 (2), 229-236
DOI 10.1111/j.1365-2141.2006.06419.x, PubMed 17278259
A clinical score predicting a brief and uneventful course of newly diagnosed idiopathic thrombocytopenic purpura in children
Br J Haematol, 138 (4), 513-6
DOI 10.1111/j.1365-2141.2007.06682.x, PubMed 17608764
Myeloid leukemia in children 4 years or older with Down syndrome often lacks GATA1 mutation and cytogenetics and risk of relapse are more akin to sporadic AML
Leukemia, 22 (7), 1428-30
DOI 10.1038/sj.leu.2405060, PubMed 18059480
[Childhood acute lymphoblastic leukemia in Norway 1992-2000]
Tidsskr Nor Laegeforen, 127 (11), 1493-5
PubMed 17551551
Analysis of JAK3, JAK2, and C-MPL mutations in transient myeloproliferative disorder and myeloid leukemia of Down syndrome blasts in children with Down syndrome
Blood, 110 (3), 1077-9
DOI 10.1182/blood-2007-03-080374, PubMed 17644747
Does treatment of newly diagnosed idiopathic thrombocytopenic purpura reduce morbidity?
Arch Dis Child, 92 (8), 704-7
DOI 10.1136/adc.2006.098442, PubMed 17460024
[Something to learn from--not only for the pediatricians]
Tidsskr Nor Laegeforen, 127 (7), 886
PubMed 17441227
Publications 2006
Optimal treatment intensity in children with Down syndrome and myeloid leukaemia: data from 56 children treated on NOPHO-AML protocols and a review of the literature
Ann Hematol, 85 (5), 275-80
DOI 10.1007/s00277-005-0045-5, PubMed 16518605
Vaccination associated thrombocytopenic purpura in children
Vaccine, 25 (10), 1838-40
DOI 10.1016/j.vaccine.2006.10.054, PubMed 17126957
Initial management of children with newly diagnosed idiopathic thrombocytopenic purpura in the Nordic countries
Acta Paediatr, 95 (6), 726-31
DOI 10.1080/08035250500486660, PubMed 16754555
Publications 2005
Treatment-related death in childhood acute lymphoblastic leukaemia in the Nordic countries: 1992-2001
Br J Haematol, 131 (1), 50-8
DOI 10.1111/j.1365-2141.2005.05736.x, PubMed 16173962
Long-term results in children with AML: NOPHO-AML Study Group--report of three consecutive trials
Leukemia, 19 (12), 2090-100
DOI 10.1038/sj.leu.2403962, PubMed 16304571
Age-dependent differences in Nordic children with ITP
J Pediatr, 146 (1), 151-2
DOI 10.1016/j.jpeds.2004.06.059, PubMed 15644852
Factors predicting development of chronic disease in Nordic children with acute onset of idiopathic thrombocytopenic purpura
Br J Haematol, 130 (1), 148-9; author reply 150
DOI 10.1111/j.1365-2141.2005.05576.x, PubMed 15982360
Acute leukaemia in children with Down syndrome: a population-based Nordic study
Br J Haematol, 128 (6), 797-804
DOI 10.1111/j.1365-2141.2005.05398.x, PubMed 15755283
Childhood idiopathic thrombocytopenic purpura in the Nordic countries: epidemiology and predictors of chronic disease
Acta Paediatr, 94 (2), 178-84
DOI 10.1111/j.1651-2227.2005.tb01887.x, PubMed 15981751
Publications 2003
Duration and morbidity of newly diagnosed idiopathic thrombocytopenic purpura in children: A prospective Nordic study of an unselected cohort
J Pediatr, 143 (3), 302-7
DOI 10.1067/s0022-3476(03)00245-2, PubMed 14517509
Publications 2002
Placental site trophoblastic tumor (PSTT) in mother and child: first report of PSTT in infancy
Med Pediatr Oncol, 38 (3), 187-91; discussion 192
DOI 10.1002/mpo.1308, PubMed 11836719
Publications 2001
[Acute pyelonephritis in children with minimal or normal urine findings]
Tidsskr Nor Laegeforen, 121 (27), 3166-9
PubMed 11876137
Publications 2000
[Kawasaki disease]
Tidsskr Nor Laegeforen, 120 (29), 3540-3
PubMed 11188381
Immune thrombocytopenic purpura in childhood in Norway: a prospective, population-based registration
Pediatr Hematol Oncol, 17 (7), 551-8
DOI 10.1080/08880010050122816, PubMed 11033730
Multisystem Langerhans-cell histiocytosis with life-threatening pulmonary involvement--good response to cyclosporine A
Med Pediatr Oncol, 35 (4), 438-42
DOI 10.1002/1096-911x(20001001)35:4<438::aid-mpo12>3.0.co;2-4, PubMed 11025480
Publications 1998
[Accidental administration of racemic adrenaline. Three life-threatening cases after intravenous injection in children]
Tidsskr Nor Laegeforen, 118 (7), 1080-1
PubMed 9531834
Publications 1997
[Transient erythroblastopenia in children. Severe anemia with good prognosis]
Tidsskr Nor Laegeforen, 117 (22), 3201-4
PubMed 9411857
Cure of infantile myofibromatosis with severe respiratory complications without antitumour therapy
Eur J Pediatr, 156 (11), 841-4
DOI 10.1007/s004310050725, PubMed 9392395
Publications 1996
[Investigation and treatment of immune thrombocytopenic purpura in children in Norway]
Tidsskr Nor Laegeforen, 116 (18), 2157-9
PubMed 8801655
[Immune thrombocytopenic purpura in children--controversy and consensus. How much investigation and treatment is meaningful?]
Tidsskr Nor Laegeforen, 116 (18), 2160-4
PubMed 8801656
Publications 1995
[Fibrodysplasia (myositis) ossificans progressiva]
Tidsskr Nor Laegeforen, 115 (28), 3496-8
PubMed 7491602