Ole Mathias Sejersted

  • Group leader, professor; MD, PhD
  • +47 23016796
Ole M. Sejersted,

Publications 2023

Li J, Sundnes J, Hou Y, Laasmaa M, Ruud M, Unger A, Kolstad TR, Frisk M, Norseng PA, Yang L, Setterberg IE, Alves ES, Kalakoutis M, Sejersted OM, Lanner JT, Linke WA, Lunde IG, de Tombe PP, Louch WE (2023)
Stretch Harmonizes Sarcomere Strain Across the Cardiomyocyte
Circ Res, 133 (3), 255-270
DOI 10.1161/CIRCRESAHA.123.322588, PubMed 37401464

Publications 2021

Carlson CR, Aronsen JM, Bergan-Dahl A, Moutty MC, Lunde M, Lunde PK, Jarstadmarken H, Wanichawan P, Pereira L, Kolstad TRS, Dalhus B, Subramanian H, Hille S, Christensen G, Müller OJ, Nikolaev V, Bers DM, Sjaastad I, Shen X, Louch WE, Klussmann E, Sejersted OM (2021)
AKAP18δ Anchors and Regulates CaMKII Activity at Phospholamban-SERCA2 and RYR
Circ Res, 130 (1), 27-44
DOI 10.1161/CIRCRESAHA.120.317976, PubMed 34814703

Danielsen TK, Sadredini M, Manotheepan R, Aronsen JM, Frisk M, Hansen MH, Andressen KW, Hougen K, Levy FO, Louch WE, Sejersted OM, Sjaastad I, Stokke MK (2021)
Exercise Training Stabilizes RyR2-Dependent Ca2+ Release in Post-infarction Heart Failure
Front Cardiovasc Med, 7, 623922
DOI 10.3389/fcvm.2020.623922, PubMed 33569394

Edwards AG, Mørk H, Stokke MK, Lipsett DB, Sjaastad I, Richard S, Sejersted OM, Louch WE (2021)
Sarcoplasmic Reticulum Calcium Release Is Required for Arrhythmogenesis in the Mouse
Front Physiol, 12, 744730
DOI 10.3389/fphys.2021.744730, PubMed 34712150

Wanichawan P, Skogestad J, Lunde M, Støle TP, Stensland M, Nyman TA, Sjaastad I, Sejersted OM, Aronsen JM, Carlson CR (2021)
Design of a Proteolytically Stable Sodium-Calcium Exchanger 1 Activator Peptide for In Vivo Studies
Front Pharmacol, 12, 638646
DOI 10.3389/fphar.2021.638646, PubMed 34163352

Publications 2020

Skogestad J, Aronsen JM, Tovsrud N, Wanichawan P, Hougen K, Stokke MK, Carlson CR, Sjaastad I, Sejersted OM, Swift F (2020)
Coupling of the Na+/K+-ATPase to Ankyrin B controls Na+/Ca2+ exchanger activity in cardiomyocytes
Cardiovasc Res, 116 (1), 78-90
DOI 10.1093/cvr/cvz087, PubMed 30949686

Tazmini K, Frisk M, Lewalle A, Laasmaa M, Morotti S, Lipsett DB, Manfra O, Skogestad J, Aronsen JM, Sejersted OM, Sjaastad I, Edwards AG, Grandi E, Niederer SA, Øie E, Louch WE (2020)
Hypokalemia Promotes Arrhythmia by Distinct Mechanisms in Atrial and Ventricular Myocytes
Circ Res, 126 (7), 889-906
DOI 10.1161/CIRCRESAHA.119.315641, PubMed 32070187

Publications 2019

Røe ÅT, Ruud M, Espe EK, Manfra O, Longobardi S, Aronsen JM, Nordén ES, Husebye T, Kolstad TRS, Cataliotti A, Christensen G, Sejersted OM, Niederer SA, Andersen GØ, Sjaastad I, Louch WE (2019)
Regional diastolic dysfunction in post-infarction heart failure: role of local mechanical load and SERCA expression
Cardiovasc Res, 115 (4), 752-764
DOI 10.1093/cvr/cvy257, PubMed 30351410

Skogestad J, Lines GT, Louch WE, Sejersted OM, Sjaastad I, Aronsen JM (2019)
Evidence for heterogeneous subsarcolemmal Na+ levels in rat ventricular myocytes
Am J Physiol Heart Circ Physiol, 316 (5), H941-H957
DOI 10.1152/ajpheart.00637.2018, PubMed 30657726

Publications 2018

Danielsen TK, Manotheepan R, Sadredini M, Leren IS, Edwards AG, Vincent KP, Lehnart SE, Sejersted OM, Sjaastad I, Haugaa KH, Stokke MK (2018)
Arrhythmia initiation in catecholaminergic polymorphic ventricular tachycardia type 1 depends on both heart rate and sympathetic stimulation
PLoS One, 13 (11), e0207100
DOI 10.1371/journal.pone.0207100, PubMed 30399185

Kolstad TR, van den Brink J, MacQuaide N, Lunde PK, Frisk M, Aronsen JM, Norden ES, Cataliotti A, Sjaastad I, Sejersted OM, Edwards AG, Lines GT, Louch WE (2018)
Ryanodine receptor dispersion disrupts Ca2+ release in failing cardiac myocytes
Elife, 7
DOI 10.7554/eLife.39427, PubMed 30375974

Publications 2017

Espe EKS, Aronsen JM, Eriksen M, Sejersted OM, Zhang L, Sjaastad I (2017)
Regional Dysfunction After Myocardial Infarction in Rats
Circ Cardiovasc Imaging, 10 (9)
DOI 10.1161/CIRCIMAGING.116.005997, PubMed 28838960

Lubelwana Hafver T, Wanichawan P, Manfra O, de Souza GA, Lunde M, Martinsen M, Louch WE, Sejersted OM, Carlson CR (2017)
Mapping the in vitro interactome of cardiac sodium (Na+ )-calcium (Ca2+ ) exchanger 1 (NCX1)
Proteomics, 17 (17-18)
DOI 10.1002/pmic.201600417, PubMed 28755400

Røe ÅT, Aronsen JM, Skårdal K, Hamdani N, Linke WA, Danielsen HE, Sejersted OM, Sjaastad I, Louch WE (2017)
Increased passive stiffness promotes diastolic dysfunction despite improved Ca2+ handling during left ventricular concentric hypertrophy
Cardiovasc Res, 113 (10), 1161-1172
DOI 10.1093/cvr/cvx087, PubMed 28472418

Publications 2016

Frisk M, Ruud M, Espe EK, Aronsen JM, Røe ÅT, Zhang L, Norseng PA, Sejersted OM, Christensen GA, Sjaastad I, Louch WE (2016)
Elevated ventricular wall stress disrupts cardiomyocyte t-tubule structure and calcium homeostasis
Cardiovasc Res, 112 (1), 443-51
DOI 10.1093/cvr/cvw111, PubMed 27226008

Hortemo KH, Lunde PK, Anonsen JH, Kvaløy H, Munkvik M, Rehn TA, Sjaastad I, Lunde IG, Aronsen JM, Sejersted OM (2016)
Exercise training increases protein O-GlcNAcylation in rat skeletal muscle
Physiol Rep, 4 (18)
DOI 10.14814/phy2.12896, PubMed 27664189

Logantha SJ, Stokke MK, Atkinson AJ, Kharche SR, Parveen S, Saeed Y, Sjaastad I, Sejersted OM, Dobrzynski H (2016)
Ca(2+)-Clock-Dependent Pacemaking in the Sinus Node Is Impaired in Mice with a Cardiac Specific Reduction in SERCA2 Abundance
Front Physiol, 7, 197
DOI 10.3389/fphys.2016.00197, PubMed 27313537

Wanichawan P, Hodne K, Hafver TL, Lunde M, Martinsen M, Louch WE, Sejersted OM, Carlson CR (2016)
Development of a high-affinity peptide that prevents phospholemman (PLM) inhibition of the sodium/calcium exchanger 1 (NCX1)
Biochem J, 473 (15), 2413-23
DOI 10.1042/BCJ20160465, PubMed 27247424

Publications 2015

Clancy CE, Chen-Izu Y, Bers DM, Belardinelli L, Boyden PA, Csernoch L, Despa S, Fermini B, Hool LC, Izu L, Kass RS, Lederer WJ, Louch WE, Maack C, Matiazzi A, Qu Z, Rajamani S, Rippinger CM, Sejersted OM, O'Rourke B, Weiss JN, Varró A, Zaza A (2015)
Deranged sodium to sudden death
J Physiol, 593 (6), 1331-45
DOI 10.1113/jphysiol.2014.281204, PubMed 25772289

Hafver TL, Hodne K, Wanichawan P, Aronsen JM, Dalhus B, Lunde PK, Lunde M, Martinsen M, Enger UH, Fuller W, Sjaastad I, Louch WE, Sejersted OM, Carlson CR (2015)
Protein Phosphatase 1c Associated with the Cardiac Sodium Calcium Exchanger 1 Regulates Its Activity by Dephosphorylating Serine 68-phosphorylated Phospholemman
J Biol Chem, 291 (9), 4561-79
DOI 10.1074/jbc.M115.677898, PubMed 26668322

Hortemo KH, Aronsen JM, Lunde IG, Sjaastad I, Lunde PK, Sejersted OM (2015)
Exhausting treadmill running causes dephosphorylation of sMLC2 and reduced level of myofilament MLCK2 in slow twitch rat soleus muscle
Physiol Rep, 3 (2)
DOI 10.14814/phy2.12285, PubMed 25713325

Publications 2014

Aronsen JM, Skogestad J, Lewalle A, Louch WE, Hougen K, Stokke MK, Swift F, Niederer S, Smith NP, Sejersted OM, Sjaastad I (2014)
Hypokalaemia induces Ca²⁺ overload and Ca²⁺ waves in ventricular myocytes by reducing Na⁺,K⁺-ATPase α₂ activity
J Physiol, 593 (6), 1509-21
DOI 10.1113/jphysiol.2014.279893, PubMed 25772299

Boardman NT, Aronsen JM, Louch WE, Sjaastad I, Willoch F, Christensen G, Sejersted O, Aasum E (2014)
Impaired left ventricular mechanical and energetic function in mice after cardiomyocyte-specific excision of Serca2
Am J Physiol Heart Circ Physiol, 306 (7), H1018-24
DOI 10.1152/ajpheart.00741.2013, PubMed 24486508

Frisk M, Koivumäki JT, Norseng PA, Maleckar MM, Sejersted OM, Louch WE (2014)
Variable t-tubule organization and Ca2+ homeostasis across the atria
Am J Physiol Heart Circ Physiol, 307 (4), H609-20
DOI 10.1152/ajpheart.00295.2014, PubMed 24951751

Wanichawan P, Hafver TL, Hodne K, Aronsen JM, Lunde IG, Dalhus B, Lunde M, Kvaløy H, Louch WE, Tønnessen T, Sjaastad I, Sejersted OM, Carlson CR (2014)
Molecular basis of calpain cleavage and inactivation of the sodium-calcium exchanger 1 in heart failure
J Biol Chem, 289 (49), 33984-98
DOI 10.1074/jbc.M114.602581, PubMed 25336645

Publications 2013

Aronsen JM, Swift F, Sejersted OM (2013)
Cardiac sodium transport and excitation-contraction coupling
J Mol Cell Cardiol, 61, 11-9
DOI 10.1016/j.yjmcc.2013.06.003, PubMed 23774049

Hortemo KH, Munkvik M, Lunde PK, Sejersted OM (2013)
Multiple causes of fatigue during shortening contractions in rat slow twitch skeletal muscle
PLoS One, 8 (8), e71700
DOI 10.1371/journal.pone.0071700, PubMed 23977116

Land S, Louch WE, Niederer SA, Aronsen JM, Christensen G, Sjaastad I, Sejersted OM, Smith NP (2013)
Beta-adrenergic stimulation maintains cardiac function in Serca2 knockout mice
Biophys J, 104 (6), 1349-56
DOI 10.1016/j.bpj.2013.01.042, PubMed 23528094

Land S, Niederer SA, Louch WE, Sejersted OM, Smith NP (2013)
Integrating multi-scale data to create a virtual physiological mouse heart
Interface Focus, 3 (2), 20120076
DOI 10.1098/rsfs.2012.0076, PubMed 24427525

Louch WE, Hake J, Mørk HK, Hougen K, Skrbic B, Ursu D, Tønnessen T, Sjaastad I, Sejersted OM (2013)
Slow Ca²⁺ sparks de-synchronize Ca²⁺ release in failing cardiomyocytes: evidence for altered configuration of Ca²⁺ release units?
J Mol Cell Cardiol, 58, 41-52
DOI 10.1016/j.yjmcc.2013.01.014, PubMed 23376034

Slettalokken G, Rehn TA, Munkvik M, Rud B, Nymark BS, Lunde PK, Sjaastad I, Sejersted OM, Hallen J (2013)
Normal training response in skeletal muscle of post-infarction heart failure patients
Eur. J. Sport Sci., 13 (2), 231-239
DOI 10.1080/17461391.2011.624197

Stokke MK, Tovsrud N, Louch WE, Øyehaug L, Hougen K, Sejersted OM, Swift F, Sjaastad I (2013)
I(CaL) inhibition prevents arrhythmogenic Ca(2+) waves caused by abnormal Ca(2+) sensitivity of RyR or SR Ca(2+) accumulation
Cardiovasc Res, 98 (2), 315-25
DOI 10.1093/cvr/cvt037, PubMed 23417043

Øyehaug L, Loose KØ, Jølle GF, Røe ÅT, Sjaastad I, Christensen G, Sejersted OM, Louch WE (2013)
Synchrony of cardiomyocyte Ca(2+) release is controlled by T-tubule organization, SR Ca(2+) content, and ryanodine receptor Ca(2+) sensitivity
Biophys J, 104 (8), 1685-97
DOI 10.1016/j.bpj.2013.03.022, PubMed 23601316

Publications 2012

Dutka TL, Verburg E, Larkins N, Hortemo KH, Lunde PK, Sejersted OM, Lamb GD (2012)
ROS-mediated decline in maximum Ca2+-activated force in rat skeletal muscle fibers following in vitro and in vivo stimulation
PLoS One, 7 (5), e35226
DOI 10.1371/journal.pone.0035226, PubMed 22629297

Espe EK, Aronsen JM, Skrbic B, Skulberg VM, Schneider JE, Sejersted OM, Zhang L, Sjaastad I (2012)
Improved MR phase-contrast velocimetry using a novel nine-point balanced motion-encoding scheme with increased robustness to eddy current effects
Magn Reson Med, 69 (1), 48-61
DOI 10.1002/mrm.24226, PubMed 22392844

Land S, Niederer SA, Aronsen JM, Espe EK, Zhang L, Louch WE, Sjaastad I, Sejersted OM, Smith NP (2012)
An analysis of deformation-dependent electromechanical coupling in the mouse heart
J Physiol, 590 (18), 4553-69
DOI 10.1113/jphysiol.2012.231928, PubMed 22615436

Li L, Louch WE, Niederer SA, Aronsen JM, Christensen G, Sejersted OM, Smith NP (2012)
Sodium accumulation in SERCA knockout-induced heart failure
Biophys J, 102 (9), 2039-48
DOI 10.1016/j.bpj.2012.03.045, PubMed 22824267

Louch WE, Stokke MK, Sjaastad I, Christensen G, Sejersted OM (2012)
No rest for the weary: diastolic calcium homeostasis in the normal and failing myocardium
Physiology (Bethesda), 27 (5), 308-23
DOI 10.1152/physiol.00021.2012, PubMed 23026754

Rehn TA, Munkvik M, Lunde PK, Sjaastad I, Sejersted OM (2012)
Intrinsic skeletal muscle alterations in chronic heart failure patients: a disease-specific myopathy or a result of deconditioning?
Heart Fail Rev, 17 (3), 421-36
DOI 10.1007/s10741-011-9289-4, PubMed 21996779

Stokke MK, Rivelsrud F, Sjaastad I, Sejersted OM, Swift F (2012)
From global to local: a new understanding of cardiac electromechanical coupling
Tidsskr Nor Laegeforen, 132 (12-13), 1457-60
DOI 10.4045/tidsskr.11.1353, PubMed 22766818

Swift F, Franzini-Armstrong C, Øyehaug L, Enger UH, Andersson KB, Christensen G, Sejersted OM, Louch WE (2012)
Extreme sarcoplasmic reticulum volume loss and compensatory T-tubule remodeling after Serca2 knockout
Proc Natl Acad Sci U S A, 109 (10), 3997-4001
DOI 10.1073/pnas.1120172109, PubMed 22355118

Publications 2011

Li L, Louch WE, Niederer SA, Andersson KB, Christensen G, Sejersted OM, Smith NP (2011)
Calcium dynamics in the ventricular myocytes of SERCA2 knockout mice: A modeling study
Biophys J, 100 (2), 322-31
DOI 10.1016/j.bpj.2010.11.048, PubMed 21244828

Munkvik M, Lunde PK, Aronsen JM, Birkeland JA, Sjaastad I, Sejersted OM (2011)
Attenuated fatigue in slow twitch skeletal muscle during isotonic exercise in rats with chronic heart failure
PLoS One, 6 (7), e22695
DOI 10.1371/journal.pone.0022695, PubMed 21799933

Sejersted OM (2011)
Calcium controls cardiac function--by all means!
J Physiol, 589 (Pt 12), 2919-20
DOI 10.1113/jphysiol.2011.210989, PubMed 21676882

Sjåland C, Lunde PK, Swift F, Munkvik M, Ericsson M, Lunde M, Boye S, Christensen G, Ellingsen Ø, Sejersted OM, Andersson KB (2011)
Slowed relaxation and preserved maximal force in soleus muscles of mice with targeted disruption of the Serca2 gene in skeletal muscle
J Physiol, 589 (Pt 24), 6139-55
DOI 10.1113/jphysiol.2011.211987, PubMed 21946846

Stokke MK, Briston SJ, Jølle GF, Manzoor I, Louch WE, Øyehaug L, Christensen G, Eisner DA, Trafford AW, Sejersted OM, Sjaastad I (2011)
Ca(2+) wave probability is determined by the balance between SERCA2-dependent Ca(2+) reuptake and threshold SR Ca(2+) content
Cardiovasc Res, 90 (3), 503-12
DOI 10.1093/cvr/cvr013, PubMed 21242164

Wanichawan P, Louch WE, Hortemo KH, Austbø B, Lunde PK, Scott JD, Sejersted OM, Carlson CR (2011)
Full-length cardiac Na+/Ca2+ exchanger 1 protein is not phosphorylated by protein kinase A
Am J Physiol Cell Physiol, 300 (5), C989-97
DOI 10.1152/ajpcell.00196.2010, PubMed 21289289

Publications 2010

Brattelid T, Winer LH, Levy FO, Liestøl K, Sejersted OM, Andersson KB (2010)
Reference gene alternatives to Gapdh in rodent and human heart failure gene expression studies
BMC Mol Biol, 11, 22
DOI 10.1186/1471-2199-11-22, PubMed 20331858

Ericsson M, Andersson KB, Amundsen BH, Torp SH, Sjaastad I, Christensen G, Sejersted OM, Ellingsen Ø (2010)
High-intensity exercise training in mice with cardiomyocyte-specific disruption of Serca2
J Appl Physiol (1985), 108 (5), 1311-20
DOI 10.1152/japplphysiol.01133.2009, PubMed 20167673

Ericsson M, Sjåland C, Andersson KB, Sjaastad I, Christensen G, Sejersted OM, Ellingsen Ø (2010)
Exercise training before cardiac-specific Serca2 disruption attenuates the decline in cardiac function in mice
J Appl Physiol (1985), 109 (6), 1749-55
DOI 10.1152/japplphysiol.00282.2010, PubMed 20864565

Hougen K, Aronsen JM, Stokke MK, Enger U, Nygard S, Andersson KB, Christensen G, Sejersted OM, Sjaastad I (2010)
Cre-loxP DNA recombination is possible with only minimal unspecific transcriptional changes and without cardiomyopathy in Tg(alphaMHC-MerCreMer) mice
Am J Physiol Heart Circ Physiol, 299 (5), H1671-8
DOI 10.1152/ajpheart.01155.2009, PubMed 20802136

Louch WE, Hake J, Jølle GF, Mørk HK, Sjaastad I, Lines GT, Sejersted OM (2010)
Control of Ca2+ release by action potential configuration in normal and failing murine cardiomyocytes
Biophys J, 99 (5), 1377-86
DOI 10.1016/j.bpj.2010.06.055, PubMed 20816049

Louch WE, Sejersted OM, Swift F (2010)
There goes the neighborhood: pathological alterations in T-tubule morphology and consequences for cardiomyocyte Ca2+ handling
J Biomed Biotechnol, 2010, 503906
DOI 10.1155/2010/503906, PubMed 20396394

Munkvik M, Rehn TA, Slettaløkken G, Hasic A, Hallén J, Sjaastad I, Sejersted OM, Lunde PK (2010)
Training effects on skeletal muscle calcium handling in human chronic heart failure
Med Sci Sports Exerc, 42 (5), 847-55
DOI 10.1249/MSS.0b013e3181c29ec1, PubMed 19996998

Slettaløkken G, Rehn TA, Munkvik M, Rud B, Sökjer-Petersen M, Lunde PK, Sjaastad I, Sejersted OM, Hallén J (2010)
Preserved metabolic reserve capacity in skeletal muscle of post-infarction heart failure patients
Scand J Med Sci Sports, 22 (2), 199-206
DOI 10.1111/j.1600-0838.2010.01226.x, PubMed 20874858

Swift F, Tovsrud N, Sjaastad I, Sejersted OM, Niggli E, Egger M (2010)
Functional coupling of alpha(2)-isoform Na(+)/K(+)-ATPase and Ca(2+) extrusion through the Na(+)/Ca(2+)-exchanger in cardiomyocytes
Cell Calcium, 48 (1), 54-60
DOI 10.1016/j.ceca.2010.06.006, PubMed 20667414

Publications 2009

Andersson KB, Birkeland JA, Finsen AV, Louch WE, Sjaastad I, Wang Y, Chen J, Molkentin JD, Chien KR, Sejersted OM, Christensen G (2009)
Moderate heart dysfunction in mice with inducible cardiomyocyte-specific excision of the Serca2 gene
J Mol Cell Cardiol, 47 (2), 180-7
DOI 10.1016/j.yjmcc.2009.03.013, PubMed 19328205

Andersson KB, Finsen AV, Sjåland C, Winer LH, Sjaastad I, Odegaard A, Louch WE, Wang Y, Chen J, Chien KR, Sejersted OM, Christensen G (2009)
Mice carrying a conditional Serca2(flox) allele for the generation of Ca(2+) handling-deficient mouse models
Cell Calcium, 46 (3), 219-25
DOI 10.1016/j.ceca.2009.07.004, PubMed 19692123

Iversen PO, Andersson KB, Finsen AV, Sjaastad I, von Lueder TG, Sejersted OM, Attramadal H, Christensen G (2009)
Separate mechanisms cause anemia in ischemic vs. nonischemic murine heart failure
Am J Physiol Regul Integr Comp Physiol, 298 (3), R808-14
DOI 10.1152/ajpregu.00250.2009, PubMed 20032264

Louch WE, Hougen K, Mørk HK, Swift F, Aronsen JM, Sjaastad I, Reims HM, Roald B, Andersson KB, Christensen G, Sejersted OM (2009)
Sodium accumulation promotes diastolic dysfunction in end-stage heart failure following Serca2 knockout
J Physiol, 588 (Pt 3), 465-78
DOI 10.1113/jphysiol.2009.183517, PubMed 20008467

Munkvik M, Lunde PK, Sejersted OM (2009)
Causes of fatigue in slow-twitch rat skeletal muscle during dynamic activity
Am J Physiol Regul Integr Comp Physiol, 297 (3), R900-10
DOI 10.1152/ajpregu.91043.2008, PubMed 19625691

Mørk HK, Sjaastad I, Sejersted OM, Louch WE (2009)
Slowing of cardiomyocyte Ca2+ release and contraction during heart failure progression in postinfarction mice
Am J Physiol Heart Circ Physiol, 296 (4), H1069-79
DOI 10.1152/ajpheart.01009.2008, PubMed 19201998

Rehn TA, Borge BA, Lunde PK, Munkvik M, Sneve ML, Grøndahl F, Aronsen JM, Sjaastad I, Prydz K, Kolset SO, Wiig H, Sejersted OM, Iversen PO (2009)
Temporary fatigue and altered extracellular matrix in skeletal muscle during progression of heart failure in rats
Am J Physiol Regul Integr Comp Physiol, 297 (1), R26-33
DOI 10.1152/ajpregu.90617.2008, PubMed 19339678

Sejersted OM (2009)
[Why not health universities?]
Tidsskr Nor Laegeforen, 129 (16), 1620
DOI 10.4045/tidsskr.09.0833, PubMed 19721472

Sharikabad MN, Aronsen JM, Haugen E, Pedersen J, Møller AS, Mørk HK, Aass HC, Sejersted OM, Sjaastad I, Brørs O (2009)
Cardiomyocytes from postinfarction failing rat hearts have improved ischemia tolerance
Am J Physiol Heart Circ Physiol, 296 (3), H787-95
DOI 10.1152/ajpheart.00796.2008, PubMed 19136604

Stokke MK, Hougen K, Sjaastad I, Louch WE, Briston SJ, Enger UH, Andersson KB, Christensen G, Eisner DA, Sejersted OM, Trafford AW (2009)
Reduced SERCA2 abundance decreases the propensity for Ca2+ wave development in ventricular myocytes
Cardiovasc Res, 86 (1), 63-71
DOI 10.1093/cvr/cvp401, PubMed 20019150

Publications 2008

Bøkenes J, Aronsen JM, Birkeland JA, Henriksen UL, Louch WE, Sjaastad I, Sejersted OM (2008)
Slow contractions characterize failing rat hearts
Basic Res Cardiol, 103 (4), 328-44
DOI 10.1007/s00395-008-0719-y, PubMed 18347833

Swift F, Birkeland JA, Tovsrud N, Enger UH, Aronsen JM, Louch WE, Sjaastad I, Sejersted OM (2008)
Altered Na+/Ca2+-exchanger activity due to downregulation of Na+/K+-ATPase alpha2-isoform in heart failure
Cardiovasc Res, 78 (1), 71-8
DOI 10.1093/cvr/cvn013, PubMed 18203708

Swift F, Birkeland JAK, Tovsrud N, Enger UH, Aronsen JM, Louch WE, Sjaastad I, Sejersted OM (2008)
Altered Na(+)/Ca(2+)-exchanger activity due to downregulation of Na(+)/K(+)-ATPase alpha(2)-isoform in heart failure (vol 78, pg 71, 2008)
Cardiovasc. Res., 79 (2), 352
DOI 10.1093/cvr/cvn147

Publications 2007

Birkeland JA, Swift F, Tovsrud N, Enger U, Lunde PK, Qvigstad E, Levy FO, Sejersted OM, Sjaastad I (2007)
Serotonin increases L-type Ca2+ current and SR Ca2+ content through 5-HT4 receptors in failing rat ventricular cardiomyocytes
Am J Physiol Heart Circ Physiol, 293 (4), H2367-76
DOI 10.1152/ajpheart.01375.2006, PubMed 17660386

Brattelid T, Qvigstad E, Birkeland JA, Swift F, Bekkevold SV, Krobert KA, Sejersted OM, Skomedal T, Osnes JB, Levy FO, Sjaastad I (2007)
Serotonin responsiveness through 5-HT2A and 5-HT4 receptors is differentially regulated in hypertrophic and failing rat cardiac ventricle
J Mol Cell Cardiol, 43 (6), 767-79
DOI 10.1016/j.yjmcc.2007.08.019, PubMed 17936780

Mørk HK, Sjaastad I, Sande JB, Periasamy M, Sejersted OM, Louch WE (2007)
Increased cardiomyocyte function and Ca2+ transients in mice during early congestive heart failure
J Mol Cell Cardiol, 43 (2), 177-86
DOI 10.1016/j.yjmcc.2007.05.004, PubMed 17574269

Swift F, Tovsrud N, Enger UH, Sjaastad I, Sejersted OM (2007)
The Na+/K+-ATPase alpha2-isoform regulates cardiac contractility in rat cardiomyocytes
Cardiovasc Res, 75 (1), 109-17
DOI 10.1016/j.cardiores.2007.03.017, PubMed 17442282

Publications 2006

Bergersen LH, Thomas M, Jóhannsson E, Waerhaug O, Halestrap A, Andersen K, Sejersted OM, Ottersen OP (2006)
Cross-reinnervation changes the expression patterns of the monocarboxylate transporters 1 and 4: An experimental study in slow and fast rat skeletal muscle
Neuroscience, 138 (4), 1105-13
DOI 10.1016/j.neuroscience.2005.12.014, PubMed 16446038

Birkeland JA, Sjaastad I, Brattelid T, Qvigstad E, Moberg ER, Krobert KA, Bjørnerheim R, Skomedal T, Sejersted OM, Osnes JB, Levy FO (2006)
Effects of treatment with a 5-HT4 receptor antagonist in heart failure
Br J Pharmacol, 150 (2), 143-52
DOI 10.1038/sj.bjp.0706966, PubMed 17160012

Lines GT, Sande JB, Louch WE, Mørk HK, Grøttum P, Sejersted OM (2006)
Contribution of the Na+/Ca2+ exchanger to rapid Ca2+ release in cardiomyocytes
Biophys J, 91 (3), 779-92
DOI 10.1529/biophysj.105.072447, PubMed 16679359

Louch WE, Mørk HK, Sexton J, Strømme TA, Laake P, Sjaastad I, Sejersted OM (2006)
T-tubule disorganization and reduced synchrony of Ca2+ release in murine cardiomyocytes following myocardial infarction
J Physiol, 574 (Pt 2), 519-33
DOI 10.1113/jphysiol.2006.107227, PubMed 16709642

Lunde PK, Sejersted OM, Thorud HM, Tønnessen T, Henriksen UL, Christensen G, Westerblad H, Bruton J (2006)
Effects of congestive heart failure on Ca2+ handling in skeletal muscle during fatigue
Circ Res, 98 (12), 1514-9
DOI 10.1161/01.RES.0000226529.66545.e5, PubMed 16690878

Laake P, Sejersted OM (2006)
[Research and research education are important]
Tidsskr Nor Laegeforen, 126 (11), 1495-6
PubMed 16732347

Swift F, Strømme TA, Amundsen B, Sejersted OM, Sjaastad I (2006)
Slow diffusion of K+ in the T tubules of rat cardiomyocytes
J Appl Physiol (1985), 101 (4), 1170-6
DOI 10.1152/japplphysiol.00297.2006, PubMed 16763106

Publications 2005

Birkeland JA, Sejersted OM, Taraldsen T, Sjaastad I (2005)
EC-coupling in normal and failing hearts
Scand Cardiovasc J, 39 (1-2), 13-23
DOI 10.1080/14017430410004632, PubMed 16097409

Bøkenes J, Sjaastad I, Sejersted OM (2005)
Artifactual contractions triggered by field stimulation of cardiomyocytes
J Appl Physiol (1985), 98 (5), 1712-9
DOI 10.1152/japplphysiol.00630.2004, PubMed 15640393

Qvigstad E, Brattelid T, Sjaastad I, Andressen KW, Krobert KA, Birkeland JA, Sejersted OM, Kaumann AJ, Skomedal T, Osnes JB, Levy FO (2005)
Appearance of a ventricular 5-HT4 receptor-mediated inotropic response to serotonin in heart failure
Cardiovasc Res, 65 (4), 869-78
DOI 10.1016/j.cardiores.2004.11.017, PubMed 15721867

Qvigstad E, Sjaastad I, Brattelid T, Nunn C, Swift F, Birkeland JA, Krobert KA, Andersen GØ, Sejersted OM, Osnes JB, Levy FO, Skomedal T (2005)
Dual serotonergic regulation of ventricular contractile force through 5-HT2A and 5-HT4 receptors induced in the acute failing heart
Circ Res, 97 (3), 268-76
DOI 10.1161/01.RES.0000176970.22603.8d, PubMed 16002744

Qvigstad E, Sjaastad I, Bøkenes J, Schiander I, Solberg L, Sejersted OM, Osnes JB, Skomedal T (2005)
Carvedilol blockade of alpha1- and beta-adrenoceptor induced inotropic responses in rats with congestive heart failure
Eur J Pharmacol, 516 (1), 51-9
DOI 10.1016/j.ejphar.2005.04.027, PubMed 15916756

Schiøtz Thorud HM, Stranda A, Birkeland JA, Lunde PK, Sjaastad I, Kolset SO, Sejersted OM, Iversen PO (2005)
Enhanced matrix metalloproteinase activity in skeletal muscles of rats with congestive heart failure
Am J Physiol Regul Integr Comp Physiol, 289 (2), R389-R394
DOI 10.1152/ajpregu.00067.2005, PubMed 15802562

Sjaastad I, Birkeland JA, Ferrier G, Howlett S, Skomedal T, Bjørnerheim R, Wasserstrom JA, Sejersted OM (2005)
Defective excitation-contraction coupling in hearts of rats with congestive heart failure
Acta Physiol Scand, 184 (1), 45-58
DOI 10.1111/j.1365-201X.2005.01431.x, PubMed 15847643

Thorud HM, Verburg E, Lunde PK, Strømme TA, Sjaastad I, Sejersted OM (2005)
Temperature-dependent skeletal muscle dysfunction in rats with congestive heart failure
J Appl Physiol (1985), 99 (4), 1500-7
DOI 10.1152/japplphysiol.00807.2004, PubMed 15932960

Publications 2004

Fauconnier J, Lacampagne A, Rauzier JM, Fontanaud P, Frapier JM, Sejersted OM, Vassort G, Richard S (2004)
Frequency-dependent and proarrhythmogenic effects of FK-506 in rat ventricular cells
Am J Physiol Heart Circ Physiol, 288 (2), H778-86
DOI 10.1152/ajpheart.00542.2004, PubMed 15471978

Schiøtz Thorud HM, Lunde PK, Nicolaysen G, Nicolaysen A, Helge JW, Nilsson GE, Sejersted OM (2004)
Muscle dysfunction during exercise of a single skeletal muscle in rats with congestive heart failure is not associated with reduced muscle blood supply
Acta Physiol Scand, 181 (2), 173-81
DOI 10.1111/j.1365-201X.2004.01285.x, PubMed 15180789

Publications 2003

Kiil F, Sejersted OM (2003)
Analysis of energy metabolism and mechanism of loop diuretics in the thick ascending limb of Henle's loop in dog kidneys
Acta Physiol Scand, 178 (1), 73-82
DOI 10.1046/j.1365-201X.2003.01058.x, PubMed 12713517

Sjaastad I, Schiander I, Sjetnan A, Qvigstad E, Bøkenes J, Sandnes D, Osnes JB, Sejersted OM, Skomedal T (2003)
Increased contribution of alpha 1- vs. beta-adrenoceptor-mediated inotropic response in rats with congestive heart failure
Acta Physiol Scand, 177 (4), 449-58
DOI 10.1046/j.1365-201X.2003.01063.x, PubMed 12648162

Sjaastad I, Wasserstrom JA, Sejersted OM (2003)
Heart failure -- a challenge to our current concepts of excitation-contraction coupling
J Physiol, 546 (Pt 1), 33-47
DOI 10.1113/jphysiol.2002.034728, PubMed 12509477

Swift F, Sjaastad I, Sejersted OM (2003)
[Does altered regulation of Na+ cause reduced myocardial contractility in heart failure?]
Tidsskr Nor Laegeforen, 123 (21), 3036-40
PubMed 14618171

Thomas MJ, Sjaastad I, Andersen K, Helm PJ, Wasserstrom JA, Sejersted OM, Ottersen OP (2003)
Localization and function of the Na+/Ca2+-exchanger in normal and detubulated rat cardiomyocytes
J Mol Cell Cardiol, 35 (11), 1325-37
DOI 10.1016/j.yjmcc.2003.08.005, PubMed 14596789

Publications 2002

Lunde PK, Verburg E, Eriksen M, Sejersted OM (2002)
Contractile properties of in situ perfused skeletal muscles from rats with congestive heart failure
J Physiol, 540 (Pt 2), 571-80
DOI 10.1113/jphysiol.2001.013324, PubMed 11956344

Schiøtz Thorud HM, Wisløff U, Lunde PK, Christensen G, Ellingsen Ø, Sejersted OM (2002)
Surgical manipulation, but not moderate exercise, is associated with increased cytokine mRNA expression in the rat soleus muscle
Acta Physiol Scand, 175 (3), 219-26
DOI 10.1046/j.1365-201X.2002.00990.x, PubMed 12100361

Sjaastad I, Bentzen JG, Semb SO, Ilebekk A, Sejersted OM (2002)
Reduced calcium tolerance in rat cardiomyocytes after myocardial infarction
Acta Physiol Scand, 175 (4), 261-9
DOI 10.1046/j.1365-201X.2002.00999.x, PubMed 12167165

Sjaastad I, Bøkenes J, Swift F, Wasserstrom JA, Sejersted OM (2002)
Normal contractions triggered by I(Ca,L) in ventricular myocytes from rats with postinfarction CHF
Am J Physiol Heart Circ Physiol, 283 (3), H1225-36
DOI 10.1152/ajpheart.00162.2001, PubMed 12181154

Tønnessen T, Sejersted OM (2002)
Molecular medicine for the cardiac surgeon
Scand Cardiovasc J, 36 (4), 201-8
DOI 10.1080/14017430260180346, PubMed 12201966

Publications 2001

Damås JK, Aukrust P, Ueland T, Odegaard A, Eiken HG, Gullestad L, Sejersted OM, Christensen G (2001)
Monocyte chemoattractant protein-1 enhances and interleukin-10 suppresses the production of inflammatory cytokines in adult rat cardiomyocytes
Basic Res Cardiol, 96 (4), 345-52
DOI 10.1007/s003950170042, PubMed 11518190

Jóhannsson E, Lunde PK, Heddle C, Sjaastad I, Thomas MJ, Bergersen L, Halestrap AP, Blackstad TW, Ottersen OP, Sejersted OM (2001)
Upregulation of the cardiac monocarboxylate transporter MCT1 in a rat model of congestive heart failure
Circulation, 104 (6), 729-34
DOI 10.1161/hc3201.092286, PubMed 11489783

Lunde PK, Dahlstedt AJ, Bruton JD, Lännergren J, Thorén P, Sejersted OM, Westerblad H (2001)
Contraction and intracellular Ca(2+) handling in isolated skeletal muscle of rats with congestive heart failure
Circ Res, 88 (12), 1299-305
DOI 10.1161/hh1201.092041, PubMed 11420307

Lunde PK, Sjaastad I, Schiøtz Thorud HM, Sejersted OM (2001)
Skeletal muscle disorders in heart failure
Acta Physiol Scand, 171 (3), 277-94
DOI 10.1046/j.1365-201x.2001.00830.x, PubMed 11412140

Skeie GO, Lunde PK, Sejersted OM, Mygland A, Aarli JA, Gilhus NE (2001)
Autoimmunity against the ryanodine receptor in myasthenia gravis
Acta Physiol Scand, 171 (3), 379-84
DOI 10.1046/j.1365-201x.2001.00841.x, PubMed 11412151

Verburg E, Thorud HM, Eriksen M, Vøllestad NK, Sejersted OM (2001)
Muscle contractile properties during intermittent nontetanic stimulation in rat skeletal muscle
Am J Physiol Regul Integr Comp Physiol, 281 (6), R1952-65
DOI 10.1152/ajpregu.2001.281.6.R1952, PubMed 11705782

Publications 2000

Sejersted OM, Sjøgaard G (2000)
Dynamics and consequences of potassium shifts in skeletal muscle and heart during exercise
Physiol Rev, 80 (4), 1411-81
DOI 10.1152/physrev.2000.80.4.1411, PubMed 11015618

Sjaastad I, Sejersted OM, Ilebekk A, Bjornerheim R (2000)
Echocardiographic criteria for detection of postinfarction congestive heart failure in rats
J Appl Physiol (1985), 89 (4), 1445-54
DOI 10.1152/jappl.2000.89.4.1445, PubMed 11007581

Wasserstrom JA, Holt E, Sjaastad I, Lunde PK, Odegaard A, Sejersted OM (2000)
Altered E-C coupling in rat ventricular myocytes from failing hearts 6 wk after MI
Am J Physiol Heart Circ Physiol, 279 (2), H798-807
DOI 10.1152/ajpheart.2000.279.2.H798, PubMed 10924080

Publications 1999

Bergersen L, Jóhannsson E, Veruki ML, Nagelhus EA, Halestrap A, Sejersted OM, Ottersen OP (1999)
Cellular and subcellular expression of monocarboxylate transporters in the pigment epithelium and retina of the rat
Neuroscience, 90 (1), 319-31
DOI 10.1016/s0306-4522(98)00427-8, PubMed 10188957

Holt E, Sjaastad I, Lunde PK, Christensen G, Sejersted OM (1999)
Thyroid hormone control of contraction and the Ca(2+)-ATPase/phospholamban complex in adult rat ventricular myocytes
J Mol Cell Cardiol, 31 (3), 645-56
DOI 10.1006/jmcc.1998.0900, PubMed 10198194

Verburg E, Hallén J, Sejersted OM, Vøllestad NK (1999)
Loss of potassium from muscle during moderate exercise in humans: a result of insufficient activation of the Na+-K+-pump?
Acta Physiol Scand, 165 (4), 357-67
DOI 10.1046/j.1365-201X.1999.00512.x, PubMed 10350230

Publications 1998

Finsnes F, Christensen G, Lyberg T, Sejersted OM, Skjønsberg OH (1998)
Increased synthesis and release of endothelin-1 during the initial phase of airway inflammation
Am J Respir Crit Care Med, 158 (5 Pt 1), 1600-6
DOI 10.1164/ajrccm.158.5.9707082, PubMed 9817714

Holt E, Tønnessen T, Lunde PK, Semb SO, Wasserstrom JA, Sejersted OM, Christensen G (1998)
Mechanisms of cardiomyocyte dysfunction in heart failure following myocardial infarction in rats
J Mol Cell Cardiol, 30 (8), 1581-93
DOI 10.1006/jmcc.1998.0724, PubMed 9737944

Lunde PK, Verburg E, Vøllestad NK, Sejersted OM (1998)
Skeletal muscle fatigue in normal subjects and heart failure patients. Is there a common mechanism?
Acta Physiol Scand, 162 (3), 215-28
DOI 10.1046/j.1365-201X.1998.0343f.x, PubMed 9578367

Sejersted OM, Vøllestad NK, Hallén J, Bahr R (1998)
Muscle performance--fatigue, recovery and trainability
Acta Physiol Scand, 162 (3), 181-2
PubMed 9578363

Semb SO, Lunde PK, Holt E, Tønnessen T, Christensen G, Sejersted OM (1998)
Reduced myocardial Na+, K(+)-pump capacity in congestive heart failure following myocardial infarction in rats
J Mol Cell Cardiol, 30 (7), 1311-28
DOI 10.1006/jmcc.1998.0696, PubMed 9710800

Skeie GO, Lunde PK, Sejersted OM, Mygland A, Aarli JA, Gilhus NE (1998)
Myasthenia gravis sera containing antiryanodine receptor antibodies inhibit binding of [3H]-ryanodine to sarcoplasmic reticulum
Muscle Nerve, 21 (3), 329-35
DOI 10.1002/(sici)1097-4598(199803)21:3<329::aid-mus6>3.0.co;2-c, PubMed 9486861

Skeie GO, Lunde PK, Sejersted OM, Mygland A, Aarli JA, Gilhus NE (1998)
Myasthenia gravis-associated ryanodine receptor antibodies inhibit binding of ryanodine to sarcoplasmic reticulum
Ann N Y Acad Sci, 841, 530-3
DOI 10.1111/j.1749-6632.1998.tb10976.x, PubMed 9668288

Tønnessen T, Lunde PK, Giaid A, Sejersted OM, Christensen G (1998)
Pulmonary and cardiac expression of preproendothelin-1 mRNA are increased in heart failure after myocardial infarction in rats. Localization of preproendothelin-1 mRNA and endothelin peptide
Cardiovasc Res, 39 (3), 633-43
DOI 10.1016/s0008-6363(98)00156-4, PubMed 9861306

Publications 1997

Holt E, Lunde PK, Sejersted OM, Christensen G (1997)
Electrical stimulation of adult rat cardiomyocytes in culture improves contractile properties and is associated with altered calcium handling
Basic Res Cardiol, 92 (5), 289-98
DOI 10.1007/BF00788941, PubMed 9486350

Jóhannsson E, Nagelhus EA, McCullagh KJ, Sejersted OM, Blackstad TW, Bonen A, Ottersen OP (1997)
Cellular and subcellular expression of the monocarboxylate transporter MCT1 in rat heart. A high-resolution immunogold analysis
Circ Res, 80 (3), 400-7
DOI 10.1161/01.res.0000435856.47954.71, PubMed 9048661

Lunde PK, Sejersted OM (1997)
Intracellular calcium signalling in striated muscle cells
Scand J Clin Lab Invest, 57 (7), 559-68
DOI 10.3109/00365519709055278, PubMed 9397486

Lunde PK, Sejersted OM (1997)
Ryanodine binding sites measured in small skeletal muscle biopsies
Scand J Clin Lab Invest, 57 (7), 569-80
DOI 10.3109/00365519709055279, PubMed 9397487

Sejersted OM (1997)
[Nobel Prize in chemistry]
Tidsskr Nor Laegeforen, 117 (30), 4359
PubMed 9456574

Semb SO, Amundsen B, Sejersted OM (1997)
A new improved way of making double-barrelled ion-selective micro-electrodes
Acta Physiol Scand, 161 (1), 1-5
DOI 10.1046/j.1365-201X.1997.00178.x, PubMed 9381941

Semb SO, Sejersted OM (1997)
Calcium induced contracture stimulates Na,K-pump rate in isolated sheep cardiac Purkinje fibers
J Mol Cell Cardiol, 29 (8), 2197-212
DOI 10.1006/jmcc.1997.0455, PubMed 9281451

Tønnessen T, Christensen G, Oie E, Holt E, Kjekshus H, Smiseth OA, Sejersted OM, Attramadal H (1997)
Increased cardiac expression of endothelin-1 mRNA in ischemic heart failure in rats
Cardiovasc Res, 33 (3), 601-10
DOI 10.1016/s0008-6363(96)00266-0, PubMed 9093530

Publications 1996

Gullestad L, Hallen J, Medbø JI, Grønnerød O, Holme I, Sejersted OM (1996)
The effect of acute vs chronic treatment with beta-adrenoceptor blockade on exercise performance, haemodynamic and metabolic parameters in healthy men and women
Br J Clin Pharmacol, 41 (1), 57-67
DOI 10.1111/j.1365-2125.1996.tb00159.x, PubMed 8824694

Gullestad L, Hallén J, Sejersted OM (1996)
K⁺ balance of the quadriceps muscle during dynamic exercise with and without β-adrenoceptor blockade
In Journal of applied physiology, The Society, Bethesda, Md., 78(1995)nr 5, S. 513-523
BIBSYS 961484284

Hallén J, Saltin B, Sejersted OM (1996)
K+ balance during exercise and role of beta-adrenergic stimulation
Am J Physiol, 270 (6 Pt 2), R1347-54
DOI 10.1152/ajpregu.1996.270.6.R1347, PubMed 8764303

Semb SO, Sejersted OM (1996)
Fuzzy space and control of Na+, K(+)-pump rate in heart and skeletal muscle
Acta Physiol Scand, 156 (3), 213-25
DOI 10.1046/j.1365-201X.1996.211000.x, PubMed 8729681

Semb SO, Sejersted OM (1996)
Fuzzy space and control of Na⁺, K⁺-pump rate in heart and skeletal muscle
In Acta physiologica Scandinavica, Blackwell, for Scandinavian Physiological Society., London, 156(1996)nr 3, S. 213-225
BIBSYS 961350792

Publications 1995

Gullestad L, Hallén J, Sejersted OM (1995)
K+ balance of the quadriceps muscle during dynamic exercise with and without beta-adrenoceptor blockade
J Appl Physiol (1985), 78 (2), 513-23
DOI 10.1152/jappl.1995.78.2.513, PubMed 7759420

Jebens E, Steen H, Fjeld TO, Bye E, Sejersted OM (1995)
Changes in Na+, K(+)-adenosinetriphosphatase, citrate synthase and K+ in sheep skeletal muscle during immobilization and remobilization
Eur J Appl Physiol Occup Physiol, 71 (5), 386-95
DOI 10.1007/BF00635871, PubMed 8565969

Sejersted OM, Hargens AR (1995)
Intramuscular pressures for monitoring different tasks and muscle conditions
Adv Exp Med Biol, 384, 339-50
DOI 10.1007/978-1-4899-1016-5_27, PubMed 8585463

Publications 1994

Børsheim E, Bahr R, Hansson P, Gullestad L, Hallén J, Sejersted OM (1994)
Effect of beta-adrenoceptor blockade on post-exercise oxygen consumption
Metabolism, 43 (5), 565-71
DOI 10.1016/0026-0495(94)90197-x, PubMed 7909912

Ellingsen O, Holthe MR, Svindland A, Aksnes G, Sejersted OM, Ilebekk A (1994)
Na,K-pump concentration in hypertrophied human hearts
Eur Heart J, 15 (9), 1184-90
DOI 10.1093/oxfordjournals.eurheartj.a060651, PubMed 7982417

Hallén J, Gullestad L, Sejersted OM (1994)
K+ shifts of skeletal muscle during stepwise bicycle exercise with and without beta-adrenoceptor blockade
J Physiol, 477 (Pt 1), 149-59
DOI 10.1113/jphysiol.1994.sp020179, PubMed 8071881

Medbø JI, Sejersted OM (1994)
Plasma K+ changes during intense exercise in endurance-trained and sprint-trained subjects
Acta Physiol Scand, 151 (3), 363-71
DOI 10.1111/j.1748-1716.1994.tb09755.x, PubMed 7976408

Opstad PK, Haugen AH, Sejersted OM, Bahr R, Skrede KK (1994)
Atrial natriuretic peptide in plasma after prolonged physical strain, energy deficiency and sleep deprivation
Eur J Appl Physiol Occup Physiol, 68 (2), 122-6
DOI 10.1007/BF00244024, PubMed 8194540

Saugen E, Hallén J, Bjørklund UH, Vøllestad NK, Sejersted OM (1994)
[Can processes connected to muscular activity explain development of chronic pain?]
Tidsskr Nor Laegeforen, 114 (10), 1195-8
PubMed 8209318

Sejersted OM (1994)
[Research on musculoskeletal diseases--the ugly duckling?]
Tidsskr Nor Laegeforen, 114 (3), 300-1
PubMed 8191421

Vøllestad NK, Hallén J, Sejersted OM (1994)
Effect of exercise intensity on potassium balance in muscle and blood of man
J Physiol, 475 (2), 359-68
DOI 10.1113/jphysiol.1994.sp020077, PubMed 8021842

Publications 1993

Gullestad L, Hallén J, Sejersted OM (1993)
Variable effects of beta-adrenoceptor blockade on muscle blood flow during exercise
Acta Physiol Scand, 149 (3), 257-71
DOI 10.1111/j.1748-1716.1993.tb09621.x, PubMed 7906074

Hallén J, Sejersted OM (1993)
Intravasal use of pliable K(+)-selective electrodes in the femoral vein of humans during exercise
J Appl Physiol (1985), 75 (5), 2318-25
DOI 10.1152/jappl.1993.75.5.2318, PubMed 8307891

Svebak S, Braathen ET, Sejersted OM, Bowim B, Fauske S, Laberg JC (1993)
Electromyographic activation and proportion of fast versus slow twitch muscle fibers: a genetic disposition for psychogenic muscle tension?
Int J Psychophysiol, 15 (1), 43-9
DOI 10.1016/0167-8760(93)90094-6, PubMed 8407433

Publications 1992

Bahr R, Grønnerød O, Sejersted OM (1992)
Effect of supramaximal exercise on excess postexercise O2 consumption
Med Sci Sports Exerc, 24 (1), 66-71
PubMed 1548999

Jebens E, Sejersted OM (1992)
Enzymatic microdetermination of plasma and serum free fatty acids
Scand J Clin Lab Invest, 52 (7), 717-24
DOI 10.3109/00365519209115517, PubMed 1455165

Publications 1991

Bahr R, Høstmark AT, Newsholme EA, Grønnerød O, Sejersted OM (1991)
Effect of exercise on recovery changes in plasma levels of FFA, glycerol, glucose and catecholamines
Acta Physiol Scand, 143 (1), 105-15
DOI 10.1111/j.1748-1716.1991.tb09205.x, PubMed 1957696

Bahr R, Opstad PK, Medbø JI, Sejersted OM (1991)
Strenuous prolonged exercise elevates resting metabolic rate and causes reduced mechanical efficiency
Acta Physiol Scand, 141 (4), 555-63
DOI 10.1111/j.1748-1716.1991.tb09117.x, PubMed 1877354

Bahr R, Sejersted OM (1991)
Effect of feeding and fasting on excess postexercise oxygen consumption
J Appl Physiol (1985), 71 (6), 2088-93
DOI 10.1152/jappl.1991.71.6.2088, PubMed 1778897

Bahr R, Sejersted OM (1991)
Effect of intensity of exercise on excess postexercise O2 consumption
Metabolism, 40 (8), 836-41
DOI 10.1016/0026-0495(91)90012-l, PubMed 1861633

Ellingsen O, Sejersted OM, Vengen OA, Ilebekk A (1991)
Frequency dependent myocardial potassium fluxes during beta adrenergic stimulation of intact pig hearts
Cardiovasc Res, 25 (5), 364-70
DOI 10.1093/cvr/25.5.364, PubMed 1855241

Publications 1990

Andersen FR, Sejersted OM, Ilebekk A (1990)
Isoprenaline augments total myocardial K+ influx of the in-situ beating porcine heart
Acta Physiol Scand, 140 (3), 413-8
DOI 10.1111/j.1748-1716.1990.tb09016.x, PubMed 2082707

Bahr R, Hansson P, Sejersted OM (1990)
Triglyceride/fatty acid cycling is increased after exercise
Metabolism, 39 (9), 993-9
DOI 10.1016/0026-0495(90)90313-2, PubMed 2392063

Kjeldsen SE, Sejersted OM, Frederichsen P, Leren P, Eide IK (1990)
Increased erythrocyte magnesium in never treated essential hypertension
Am J Hypertens, 3 (7), 573-5
DOI 10.1093/ajh/3.7.573, PubMed 2194511

Kjeldsen SE, Sejersted OM, Frederichsen P, Leren P, Eide IK (1990)
Increased erythrocyte magnesium content in essential hypertension
Scand J Clin Lab Invest, 50 (4), 395-400
DOI 10.3109/00365519009091597, PubMed 2392652

Medbø JI, Sejersted OM (1990)
Plasma potassium changes with high intensity exercise
J Physiol, 421, 105-22
DOI 10.1113/jphysiol.1990.sp017935, PubMed 2348388

Vøllestad NK, Wesche J, Sejersted OM (1990)
Gradual increase in leg oxygen uptake during repeated submaximal contractions in humans
J Appl Physiol (1985), 68 (3), 1150-6
DOI 10.1152/jappl.1990.68.3.1150, PubMed 2341340

Publications 1989

Ellingsen O, Sejersted OM, Vengen OA, Ilebekk A (1989)
In-vivo quantification of myocardial Na-K pump rate during beta-adrenergic stimulation of intact pig hearts
Acta Physiol Scand, 135 (4), 493-503
DOI 10.1111/j.1748-1716.1989.tb08608.x, PubMed 2567565

Kjeldsen SE, Sejersted OM, Frederichsen P, Leren P, Eide IK (1989)
Increased erythrocyte magnesium in untreated essential hypertension
J Hypertens Suppl, 7 (6), S156-7
DOI 10.1097/00004872-198900076-00074, PubMed 2632702

Publications 1988

Ellingsen O, Vengen OA, Sejersted OM, Ilebekk A (1988)
Temporal relationship of contractility and myocardial potassium balance following beta-adrenergic stimulation of the in situ pig heart
Acta Physiol Scand, 132 (2), 241-50
DOI 10.1111/j.1748-1716.1988.tb08323.x, PubMed 2906501

Medbø JI, Mohn AC, Tabata I, Bahr R, Vaage O, Sejersted OM (1988)
Anaerobic capacity determined by maximal accumulated O2 deficit
J Appl Physiol (1985), 64 (1), 50-60
DOI 10.1152/jappl.1988.64.1.50, PubMed 3356666

Sejersted OM (1988)
Maintenance of Na,K-homeostasis by Na,K-pumps in striated muscle
Prog Clin Biol Res, 268B, 195-206
PubMed 2851799

Sejersted OM, Wasserstrom JA, Fozzard HA (1988)
Na,K pump stimulation by intracellular Na in isolated, intact sheep cardiac Purkinje fibers
J Gen Physiol, 91 (3), 445-66
DOI 10.1085/jgp.91.3.445, PubMed 2454287

Sejersted OM, Westgaard RH (1988)
Occupational muscle pain and injury; scientific challenge
Eur J Appl Physiol Occup Physiol, 57 (3), 271-4
DOI 10.1007/BF00635984, PubMed 3371335

Vøllestad NK, Sejersted OM (1988)
Biochemical correlates of fatigue. A brief review
Eur J Appl Physiol Occup Physiol, 57 (3), 336-47
DOI 10.1007/BF00635993, PubMed 3286252

Vøllestad NK, Sejersted OM, Bahr R, Woods JJ, Bigland-Ritchie B (1988)
Motor drive and metabolic responses during repeated submaximal contractions in humans
J Appl Physiol (1985), 64 (4), 1421-7
DOI 10.1152/jappl.1988.64.4.1421, PubMed 3378978

Publications 1987

Bahr R, Ingnes I, Vaage O, Sejersted OM, Newsholme EA (1987)
Effect of duration of exercise on excess postexercise O2 consumption
J Appl Physiol (1985), 62 (2), 485-90
DOI 10.1152/jappl.1987.62.2.485, PubMed 3558208

Ellingsen O, Sejersted OM, Leraand S, Ilebekk A (1987)
Catecholamine-induced myocardial potassium uptake mediated by beta 1-adrenoceptors and adenylate cyclase activation in the pig
Circ Res, 60 (4), 540-50
DOI 10.1161/01.res.60.4.540, PubMed 3036391

Ovrebø S, Jacobsen D, Sejersted OM (1987)
Determination of ionic metabolites from ethylene glycol in human blood by isotachophoresis
J Chromatogr, 416 (1), 111-7
DOI 10.1016/0378-4347(87)80490-5, PubMed 3597625

Publications 1986

Exercise in Human Physiology, Vøllestad NK, Sejersted OM, Hermansen L (1986)
Exercise in human physiology: international symposium in memory of Lars Hermansen
Blackwell Scientific Publ., [Oxford], 167 s.
BIBSYS 942805232, ISBN 82-90688-00-8

Ilebekk A, Andersen FR, Sejersted OM (1986)
Magnitude of myocardial potassium changes during acute alterations in pacing frequency in the in situ pig heart
Cardiovasc Res, 20 (3), 176-81
DOI 10.1093/cvr/20.3.176, PubMed 3708653

Kiil F, Hartmann A, Langberg H, Sejersted OM, Holthe MR (1986)
Renal Na,K-adenosine triphosphatase transport rate limits transcellular NaCl reabsorption in distal nephrons of volume-expanded dogs
J Pharmacol Exp Ther, 238 (1), 327-33
PubMed 3014121

Maehlum S, Grandmontagne M, Newsholme EA, Sejersted OM (1986)
Magnitude and duration of excess postexercise oxygen consumption in healthy young subjects
Metabolism, 35 (5), 425-9
DOI 10.1016/0026-0495(86)90132-0, PubMed 3517556

Sejersted OM, Vøllestad NK, Medbø JI (1986)
Muscle fluid and electrolyte balance during and following exercise
Acta Physiol Scand Suppl, 556, 119-27
PubMed 3471049

Publications 1985

Grotmol T, Buanes T, Mathisen O, Schistad O, Sejersted OM, Raeder MG (1985)
Effects of digitoxin and hypokalaemia on pancreatic NaHCO3 secretion and pancreatic Na,K-ATPase activity
Acta Physiol Scand, 124 (1), 71-80
DOI 10.1111/j.1748-1716.1985.tb07633.x, PubMed 2409747

Medbø JI, Sejersted OM (1985)
Acid-base and electrolyte balance after exhausting exercise in endurance-trained and sprint-trained subjects
Acta Physiol Scand, 125 (1), 97-109
DOI 10.1111/j.1748-1716.1985.tb07696.x, PubMed 4050490

Sejersted OM, Andersen FR, Ilebekk A (1985)
Potassium balance and ouabain binding sites in intact porcine hearts during isoproterenol infusion
Adv Myocardiol, 6, 83-95
PubMed 3992054

Sejersted OM, Monclair T, Mathisen O, Hartmann A, Kiil F (1985)
Dependency of renal potassium excretion on Na,K-ATPase transport rate
Acta Physiol Scand, 123 (1), 9-19
DOI 10.1111/j.1748-1716.1985.tb07555.x, PubMed 2982247

Sejersted OM, Nicolaysen A, Monclair T, Nicolaysen G (1985)
Distribution of ouabain-binding sites along the dog nephron
Acta Physiol Scand, 125 (4), 699-710
DOI 10.1111/j.1748-1716.1985.tb07773.x, PubMed 3004109

Vikse A, Holdaas H, Sejersted OM, Kiil F (1985)
Haemodynamic conditions for renal PGE2 and renin release during alpha- and beta-adrenergic stimulation in dogs
Acta Physiol Scand, 124 (2), 163-72
DOI 10.1111/j.1748-1716.1985.tb07648.x, PubMed 2861715

Vikse A, Sejersted OM, Kiil F (1985)
Autoregulatory vasodilation enhances renal prostaglandin E2 and associated renin release during arachidonic acid infusion in dogs
J Pharmacol Exp Ther, 234 (1), 261-6
PubMed 3925129

Publications 1984

Jacobsen D, Ovrebø S, Ostborg J, Sejersted OM (1984)
Glycolate causes the acidosis in ethylene glycol poisoning and is effectively removed by hemodialysis
Acta Med Scand, 216 (4), 409-16
PubMed 6516909

Langård O, Holdaas H, Vikse A, Sejersted OM, Eide I (1984)
Ouabain inhibits renin release by a direct renal haemodynamic effect
Scand J Clin Lab Invest, 44 (6), 557-63
DOI 10.1080/00365518409083611, PubMed 6148785

Sejersted OM, Hargens AR, Kardel KR, Blom P, Jensen O, Hermansen L (1984)
Intramuscular fluid pressure during isometric contraction of human skeletal muscle
J Appl Physiol Respir Environ Exerc Physiol, 56 (2), 287-95
DOI 10.1152/jappl.1984.56.2.287, PubMed 6706739

Sejersted OM, Steen PA, Kiil F (1984)
Inhibition of transcellular NaCl reabsorption in dog kidneys during hypercalcemia
Acta Physiol Scand, 120 (4), 543-9
DOI 10.1111/j.1748-1716.1984.tb07419.x, PubMed 6091415

Sejersted OM, Vikse A, Eide I, Kiil F (1984)
Renal venous and urinary PGE2 output during intrarenal arachidonic acid infusion in dogs
Acta Physiol Scand, 121 (3), 249-59
DOI 10.1111/j.1748-1716.1984.tb07454.x, PubMed 6433651

Vikse A, Holdaas H, Sejersted OM, Kiil F (1984)
Relationship between PGE2 and renin release in dog kidneys. Effects of afferent arteriolar dilation and adrenergic stimulation
Acta Physiol Scand, 121 (3), 261-8
DOI 10.1111/j.1748-1716.1984.tb07455.x, PubMed 6382924

Publications 1983

Andersen FR, Sejersted OM, Ilebekk A (1983)
A model for quantitative sampling of myocardial venous blood in the pig
Acta Physiol Scand, 119 (2), 187-95
DOI 10.1111/j.1748-1716.1983.tb07325.x, PubMed 6659986

Jacobsen D, Ovrebø S, Sejersted OM (1983)
Toxicokinetics of formate during hemodialysis
Acta Med Scand, 214 (5), 409-12
DOI 10.1111/j.0954-6820.1983.tb08616.x, PubMed 6660049

Sejersted OM, Jacobsen D, Ovrebø S, Jansen H (1983)
Formate concentrations in plasma from patients poisoned with methanol
Acta Med Scand, 213 (2), 105-10
DOI 10.1111/j.0954-6820.1983.tb03699.x, PubMed 6837328

Vikse A, Holdaas H, Sejersted OM, Eide I, Kiil F (1983)
Prostaglandin E2 and renin release response to dilation of afferent arterioles and during alpha- and beta-adrenergic stimulation
Acta Med Scand Suppl, 677, 44-7
DOI 10.1111/j.0954-6820.1984.tb08627.x, PubMed 6322531

Publications 1982

Sejersted OM (1982)
Lack of stimulation of renal (Na+ +K+)-ATPase by thyroid hormones in the rabbit
Biochim Biophys Acta, 717 (1), 163-74
DOI 10.1016/0304-4165(82)90394-4, PubMed 6285989

Sejersted OM, Medbø JI, Hermansen L (1982)
Metabolic acidosis and changes in water and electrolyte balance after maximal exercise
Ciba Found Symp, 87, 153-67
DOI 10.1002/9780470720691.ch9, PubMed 6804191

Sejersted OM, Steen PA, Kiil F (1982)
Energetics of tubular sodium reabsorption sensitive to ethacrynic acid and ouabain
Am J Physiol, 242 (3), F254-60
DOI 10.1152/ajprenal.1982.242.3.F254, PubMed 6278951

Publications 1981

Ostborg J, Sejersted OM, Jansen H (1981)
[Methanol poisoning. Diagnostic and differential diagnostic problems illustrated by 2 cases]
Tidsskr Nor Laegeforen, 101 (12), 697-9
PubMed 7245153

Sejersted OM, Jacobsen D, Ovrebø S (1981)
Methanol poisoning
Lancet, 2 (8260-61), 1426
DOI 10.1016/s0140-6736(81)92844-0, PubMed 6118796

Sejersted OM, Ostborg J, Jansen H (1981)
[Methanol poisoning. Emergency measures, diagnostic and therapeutic problems during the Kristiansand outbreak in 1979]
Tidsskr Nor Laegeforen, 101 (12), 699-706
PubMed 7245154

Steen PA, Sejersted OM, Hartmann A, Kiil F (1981)
Transcellular and intercellular transport of anions in the kidney tubules of dogs
Acta Physiol Scand, 113 (2), 239-44
DOI 10.1111/j.1748-1716.1981.tb06889.x, PubMed 6797256

Publications 1980

Kiil F, Sejersted OM, Steen PA (1980)
Energetics and specificity of transcellular NaCl transport in the dog kidney
Int J Biochem, 12 (1-2), 245-50
DOI 10.1016/0020-711x(80)90079-8, PubMed 6249658

Monclair T, Sejersted OM, Kiil F (1980)
Influence of plasma potassium concentration on the capacity for sodium reabsorption in the diluting segment of the kidney
Scand J Clin Lab Invest, 40 (1), 27-36
DOI 10.3109/00365518009091524, PubMed 7367809

Publications 1979

Sejersted OM (1979)
Estimation of ouabain specifically bound to dog renal (Na+ + K+)-ATPase in vivo
Biochim Biophys Acta, 586 (2), 330-40
DOI 10.1016/0304-4165(79)90103-x, PubMed 224940

Publications 1978

Sejersted OM (1978)
Function of Na-K-ATPase in renal sodium reabsorption
J Oslo City Hosp, 28 (10), 129-37
PubMed 211212

Sejersted OM (1978)
Function of na-K-ATPase in renal sodium reabsorption
University of Oslo, Institute for Experimental Medical Research, Ullevål Hospital, Oslo, l b. (fl. pag.)
BIBSYS 823074072, ISBN 82-90246-00-5

Sejersted OM, Holdaas H, Monclair T (1978)
Functional differences of ouabain and ethacrynic acid on renal potassium metabolism in dogs
Scand J Clin Lab Invest, 38 (7), 603-14
DOI 10.3109/00365517809102426, PubMed 152453

Sejersted OM, Urdal K (1978)
[Board practice before and after the new abortion act of June 13, 1975. A comparison of boards in Oslo during 1971/1972, and 1975 and 1976]
Tidsskr Nor Laegeforen, 98 (29), 1428-32
PubMed 705732

Publications 1977

Sejersted OM (1977)
Renal Na-K-ATPase activity during saline infusion in the rabbit
Acta Physiol Scand, 99 (3), 323-35
DOI 10.1111/j.1748-1716.1977.tb10385.x, PubMed 139820

Sejersted OM, Mathisen O, Kiil F (1977)
Oxygen requirement of renal Na-K-ATPase-dependent sodium reabsorption
Am J Physiol, 232 (2), 152-8
DOI 10.1152/ajprenal.1977.232.2.F152, PubMed 139108

Publications 1976

Ganes T, Sejersted O (1976)
[Abortion-seeking women's views on the importance of social benefits as an alternative to induced abortion]
Tidsskr Nor Laegeforen, 96 (13), 768-70
PubMed 936152

Mathisen O, Raeder M, Sejersted OM, Kiil F (1976)
Effect of acetazolamide on glomerular balance and renal metabolic rate
Scand J Clin Lab Invest, 36 (7), 617-25
DOI 10.3109/00365517609054486, PubMed 1019572

Publications 1974

Lie M, Sejersted OM, Raeder M, Kiil F (1974)
Comparison of renal responses to ouabain and ethacrynic acid
Am J Physiol, 226 (5), 1121-6
DOI 10.1152/ajplegacy.1974.226.5.1220, PubMed 4824865

Publications 1971

Sejersted OM, Lie M, Kiil F (1971)
Effect of ouabain on metabolic rate in renal cortex and medulla
Am J Physiol, 220 (5), 1488-93
DOI 10.1152/ajplegacy.1971.220.5.1488, PubMed 4252489

Publications 1970

Lie M, Sejersted OM, Kiil F (1970)
Local regulation of vascular cross section during changes in femoral arterial blood flow in dogs
Circ Res, 27 (5), 727-37
DOI 10.1161/01.res.27.5.727, PubMed 5486244

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