Publications:
Publications published since 2000 from OUS - Institute for Experimental Medical Research (IEMR)
836 publications found
Publications 2024
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Novel cardiac extracellular matrix biomarkers in STEMI: Associations with ischemic injury and long-term mortality
PLoS One, 19 (5), e0302732
DOI 10.1371/journal.pone.0302732, PubMed 38739599 -
Cellular immunity against cytomegalovirus and risk of infection after kidney transplantation
Front Immunol, 15, 1414830
DOI 10.3389/fimmu.2024.1414830, PubMed 39007131 -
Novel biomarkers in patients with uncontrolled hypertension with and without kidney damage
Blood Press, 33 (1), 2323980
DOI 10.1080/08037051.2024.2323980, PubMed 38606688 -
Editorial for "MRI Assessment of Myocardial Deformation for Risk Stratification of Major Arrhythmic Events in Patients with Non-Ischemic Cardiomyopathy Eligible for Primary Prevention Implantable Cardioverter Defibrillators"
J Magn Reson Imaging, 60 (5), 1987-1988
DOI 10.1002/jmri.29300, PubMed 38358060 -
Reply: Navigating Nutritional Nuances in the Research of Heart Failure With Preserved Ejection Fraction
JACC Basic Transl Sci, 9 (3), 403
DOI 10.1016/j.jacbts.2024.01.014, PubMed 38559617 -
Editorial for "Impact of Type 2 Diabetes Mellitus on Left Atrioventricular Coupling and Left Atrial Deformation in Patients With Essential Hypertension: An MRI Feature Tracking Study"
J Magn Reson Imaging (in press)
DOI 10.1002/jmri.29472, PubMed 38887801 -
Cerebral perfusion and metabolism with mild hypercapnia vs. normocapnia in a porcine post cardiac arrest model with and without targeted temperature management
Resusc Plus, 18, 100604
DOI 10.1016/j.resplu.2024.100604, PubMed 38510376 -
Neutrophil Extracellular Traps in ST-Segment Elevation Myocardial Infarction: Reduced by Tocilizumab and Associated With Infarct Size
JACC Adv, 3 (9), 101193
DOI 10.1016/j.jacadv.2024.101193, PubMed 39247678 -
Resting membrane potential and intracellular [Na+] at rest, during fatigue and during recovery in rat soleus muscle fibres in situ
J Physiol, 602 (14), 3469-3487
DOI 10.1113/JP285870, PubMed 38877870 -
Myocardial SERCA2 Protects Against Cardiac Damage and Dysfunction Caused by Inhaled Bromine
J Pharmacol Exp Ther, 390 (1), 146-158
DOI 10.1124/jpet.123.002084, PubMed 38772719 -
Fibroblast integrin α11β1 is a collagen assembly receptor in mechanoregulated fibrillar adhesions
Matrix Biol (in press)
DOI 10.1016/j.matbio.2024.10.006, PubMed 39406317 -
Correction: Noureddine et al. Impact of the Renin-Angiotensin System on the Endothelium in Vascular Dementia: Unresolved Issues and Future Perspectives. Int. J. Mol. Sci. 2020, 21, 4268
Int J Mol Sci, 25 (5)
DOI 10.3390/ijms25052995, PubMed 38474326 -
Regulation of cardiomyocyte t-tubule structure by preload and afterload: Roles in cardiac compensation and decompensation
J Physiol, 602 (18), 4487-4510
DOI 10.1113/JP284566, PubMed 38686538 -
Lessons on the non-linear path of medical progress and biological complexity from mouse models of the Brugada syndrome
Europace, 26 (6)
DOI 10.1093/europace/euae152, PubMed 38874401 -
Electrophysiological tolerance - a new concept for understanding the electrical stability of the heart
Europace (in press)
DOI 10.1093/europace/euae282, PubMed 39487808 -
Exploring Syndecan-4 and MLP and Their Interaction in Primary Cardiomyocytes and H9c2 Cells
Cells, 13 (11)
DOI 10.3390/cells13110947, PubMed 38891079 -
High-sensitive troponinT, interleukin-8, and interleukin-6 link with post-surgery risk in infant heart surgery
Acta Anaesthesiol Scand, 68 (6), 745-752
DOI 10.1111/aas.14405, PubMed 38531618 -
Alveolar hypoxia induces organ-specific inflammasome-related inflammation in male mouse lungs
Physiol Rep, 12 (14), e16143
DOI 10.14814/phy2.16143, PubMed 39034131 -
Importance of environmental signals for cardiac morphological development in Atlantic salmon
J Exp Biol, 227 (20)
DOI 10.1242/jeb.247557, PubMed 39387107 -
Enhanced Ca2+-Driven Arrhythmias in Female Patients with Atrial Fibrillation: Insights from Computational Modeling
bioRxiv
DOI 10.1101/2024.03.04.583217, PubMed 38496584 -
Enhanced Ca2+-Driven Arrhythmogenic Events in Female Patients With Atrial Fibrillation: Insights From Computational Modeling
JACC Clin Electrophysiol (in press)
DOI 10.1016/j.jacep.2024.07.020, PubMed 39340505
Publications 2023
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Beneficial effects of exercise initiated before development of hypertrophic cardiomyopathy in genotype-positive mice
Am J Physiol Heart Circ Physiol, 324 (6), H881-H892
DOI 10.1152/ajpheart.00701.2022, PubMed 37115627 -
Novel enhancers of guanylyl cyclase-A activity acting via allosteric modulation
Br J Pharmacol, 180 (24), 3254-3270
DOI 10.1111/bph.16203, PubMed 37522273 -
Response by Aronsen et al to Letter Regarding Article, "Disruption of Phosphodiesterase 3A Binding to SERCA2 Increases SERCA2 Activity and Reduces Mortality in Mice With Chronic Heart Failure"
Circulation, 148 (10), 857-858
DOI 10.1161/CIRCULATIONAHA.123.065884, PubMed 37669357 -
Cardiac dysfunction in mixed connective tissue disease: a nationwide observational study
Rheumatol Int, 43 (6), 1055-1065
DOI 10.1007/s00296-023-05308-3, PubMed 36933069 -
Cardiac Troponin T and NT-proBNP for Prediction of 30-Day Readmission or Death in Patients with Acute Dyspnea: Data from the Akershus Cardiac Examination 2 Study
Cardiology, 148 (6), 506-516
DOI 10.1159/000533266, PubMed 37544298 -
Cytomegalovirus High-risk Kidney Transplant Recipients Show No Difference in Long-term Outcomes Following Preemptive Versus Prophylactic Management
Transplantation, 107 (8), 1846-1853
DOI 10.1097/TP.0000000000004615, PubMed 37211633 -
Diagnostic accuracy of circular RNA for diabetes Mellitus: a systematic review and diagnostic Meta-analysis
BMC Med Genomics, 16 (1), 48
DOI 10.1186/s12920-023-01476-0, PubMed 36890575 -
Editorial for "Reference Ranges of Ventricular Morphology and Function in Healthy Chinese Adults: A Multicenter 3T MRI Study"
J Magn Reson Imaging, 59 (3), 823-824
DOI 10.1002/jmri.28901, PubMed 37461182 -
Caloric Restriction Rejuvenates Skeletal Muscle Growth in Heart Failure With Preserved Ejection Fraction
JACC Basic Transl Sci, 9 (2), 223-240
DOI 10.1016/j.jacbts.2023.09.014, PubMed 38510717 -
A single amino acid deletion in the ER Ca2+ sensor STIM1 reverses the in vitro and in vivo effects of the Stormorken syndrome-causing R304W mutation
Sci Signal, 16 (771), eadd0509
DOI 10.1126/scisignal.add0509, PubMed 36749824 -
Myocardial oxidative stress is increased in early reperfusion, but systemic antioxidative therapy does not prevent ischemia-reperfusion arrhythmias in pigs
Front Cardiovasc Med, 10, 1223496
DOI 10.3389/fcvm.2023.1223496, PubMed 37823177 -
Multimodal human thymic profiling reveals trajectories and cellular milieu for T agonist selection
Front Immunol, 13, 1092028
DOI 10.3389/fimmu.2022.1092028, PubMed 36741401 -
Live-cell photo-activated localization microscopy correlates nanoscale ryanodine receptor configuration to calcium sparks in cardiomyocytes
Nat Cardiovasc Res, 2 (3), 251-267
DOI 10.1038/s44161-022-00199-2, PubMed 38803363 -
Stretch Harmonizes Sarcomere Strain Across the Cardiomyocyte
Circ Res, 133 (3), 255-270
DOI 10.1161/CIRCRESAHA.123.322588, PubMed 37401464 -
The Association Between Inflammatory Cell Response and Change in Infarct Size Following STEMI
JACC Adv, 2 (9), 100660
DOI 10.1016/j.jacadv.2023.100660, PubMed 38938737 -
Polyarginine Cell-Penetrating Peptides Bind and Inhibit SERCA2
Cells, 12 (19)
DOI 10.3390/cells12192358, PubMed 37830576 -
Augmenting workload drives T-tubule assembly in developing cardiomyocytes
J Physiol, 602 (18), 4461-4486
DOI 10.1113/JP284538, PubMed 37128962 -
Adipokine profile in long-term juvenile dermatomyositis, and associations with adipose tissue distribution and cardiac function: a cross-sectional study
RMD Open, 9 (1)
DOI 10.1136/rmdopen-2022-002815, PubMed 36828644 -
Adipose tissue distribution is associated with cardio-metabolic alterations in adult patients with juvenile-onset dermatomyositis
Rheumatology (Oxford), 62 (SI2), SI196-SI204
DOI 10.1093/rheumatology/keac293, PubMed 35575380 -
Two Transient Receptor Potential Channels at Focal Adhesions
J Histochem Cytochem, 71 (9), 495-508
DOI 10.1369/00221554231194119, PubMed 37596792 -
Recurrent malignant ventricular arrhythmias and paresthesia-a mystery revealed as aconitine poisoning: a case report
J Med Case Rep, 17 (1), 554
DOI 10.1186/s13256-023-04304-2, PubMed 38129927 -
Clinical efficacy of buprenorphine after oral dosing in rats undergoing major surgery
Lab Anim, 58 (1), 34-43
DOI 10.1177/00236772231178417, PubMed 37669442 -
Lung tissue injury and hemodynamic effects of ventilations synchronized or unsynchronized to continuous chest compressions in a porcine cardiac arrest model
Resusc Plus, 17, 100530
DOI 10.1016/j.resplu.2023.100530, PubMed 38155976 -
Characterization of wooden breast myopathy: a focus on syndecans and ECM remodeling
Front Physiol, 14, 1301804
DOI 10.3389/fphys.2023.1301804, PubMed 38130476 -
BIN1, Myotubularin, and Dynamin-2 Coordinate T-Tubule Growth in Cardiomyocytes
Circ Res, 132 (11), e188-e205
DOI 10.1161/CIRCRESAHA.122.321732, PubMed 37139790 -
Vibrational spectroscopy identifies myocardial chemical modifications in heart failure with preserved ejection fraction
J Transl Med, 21 (1), 617
DOI 10.1186/s12967-023-04465-0, PubMed 37697391 -
FTIR Analysis of Renal Tissue for the Assessment of Hypertensive Organ Damage and proANP31-67 Treatment
Int J Mol Sci, 24 (6)
DOI 10.3390/ijms24065196, PubMed 36982271 -
Temporal expression and spatial distribution of the proteoglycan versican during cardiac fibrosis development
Matrix Biol Plus, 19-20, 100135
DOI 10.1016/j.mbplus.2023.100135, PubMed 38076279 -
Disruption of Phosphodiesterase 3A Binding to SERCA2 Increases SERCA2 Activity and Reduces Mortality in Mice With Chronic Heart Failure
Circulation, 147 (16), 1221-1236
DOI 10.1161/CIRCULATIONAHA.121.054168, PubMed 36876489 -
Inflammation and Syndecan-4 Shedding from Cardiac Cells in Ischemic and Non-Ischemic Heart Disease
Biomedicines, 11 (4)
DOI 10.3390/biomedicines11041066, PubMed 37189684 -
Inflammatory augmentation of the delayed type hypersensitivity arthritis mouse model
Basic Clin Pharmacol Toxicol, 132 (6), 551-555
DOI 10.1111/bcpt.13864, PubMed 36946742 -
Inhibition of the extracellular enzyme A disintegrin and metalloprotease with thrombospondin motif 4 prevents cardiac fibrosis and dysfunction
Cardiovasc Res, 119 (10), 1915-1927
DOI 10.1093/cvr/cvad078, PubMed 37216909 -
The bacterial magnesium transporter MgtA reveals highly selective interaction with specific cardiolipin species
Biochim Biophys Acta Mol Cell Res, 1871 (1), 119614
DOI 10.1016/j.bbamcr.2023.119614, PubMed 37879515 -
Utility of the Inferior Axis and Left Bundle Branch Block Pattern for Categorization of Patients With Premature Ventricular Complexes Before Catheter Ablation
Am J Cardiol, 201, 148-149
DOI 10.1016/j.amjcard.2023.06.013, PubMed 37385167
Publications 2022
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Exercise training during childhood and adolescence is associated with favorable diastolic function in hypertrophic cardiomyopathy
Int J Cardiol, 364, 65-71
DOI 10.1016/j.ijcard.2022.06.042, PubMed 35714718 -
Prognostic value of cardiac biomarkers and National Early Warning Score 2 in acute dyspnoea
Open Heart, 9 (1)
DOI 10.1136/openhrt-2021-001938, PubMed 35387863 -
Blocking phospholamban with VHH intrabodies enhances contractility and relaxation in heart failure
Nat Commun, 13 (1), 3018
DOI 10.1038/s41467-022-29703-9, PubMed 35641497 -
Tubulator: an automated approach to analysis of t-tubule and dyadic organization in cardiomyocytes
Philos Trans R Soc Lond B Biol Sci, 377 (1864), 20210468
DOI 10.1098/rstb.2021.0468, PubMed 36189810 -
One step closer to myocardial physiology: From PV loop analysis to state-of-the-art myocardial imaging
Acta Physiol (Oxf), 234 (2), e13759
DOI 10.1111/apha.13759, PubMed 34978759 -
CaMKII and reactive oxygen species contribute to early reperfusion arrhythmias, but oxidation of CaMKIIδ at methionines 281/282 is not a determining factor
J Mol Cell Cardiol, 175, 49-61
DOI 10.1016/j.yjmcc.2022.12.002, PubMed 36528076 -
Nanoscale organization of ryanodine receptor distribution and phosphorylation pattern determines the dynamics of calcium sparks
PLoS Comput Biol, 18 (6), e1010126
DOI 10.1371/journal.pcbi.1010126, PubMed 35666763 -
A TRP to the emergency room: Understanding arrhythmia in the ageing heart
Cardiovasc Res, 118 (4), 932-933
DOI 10.1093/cvr/cvac017, PubMed 35225325 -
Image-Driven Modeling of Nanoscopic Cardiac Function: Where Have We Come From, and Where Are We Going?
Front Physiol, 13, 834211
DOI 10.3389/fphys.2022.834211, PubMed 35356084 -
Editorial: Nanodomain regulation of muscle physiology and alterations in disease
Front Physiol, 13, 1092304
DOI 10.3389/fphys.2022.1092304, PubMed 36523550 -
Cardiomyocyte-specific overexpression of syndecan-4 in mice results in activation of calcineurin-NFAT signalling and exacerbated cardiac hypertrophy
Mol Biol Rep, 49 (12), 11795-11809
DOI 10.1007/s11033-022-07985-y, PubMed 36205855 -
Calcineurin-NFAT dynamics correspond to cardiac remodeling during aortic banding and debanding, mimicking aortic valve replacement
Front Mol Med, 2, 980717
DOI 10.3389/fmmed.2022.980717, PubMed 39086965 -
Diagnostic performance of microRNAs in the detection of heart failure with reduced or preserved ejection fraction: a systematic review and meta-analysis
Eur J Heart Fail, 24 (12), 2212-2225
DOI 10.1002/ejhf.2700, PubMed 36161443 -
Lumican accumulates with fibrillar collagen in fibrosis in hypertrophic cardiomyopathy
ESC Heart Fail, 10 (2), 858-871
DOI 10.1002/ehf2.14234, PubMed 36444917 -
MSK-Mediated Phosphorylation of Histone H3 Ser28 Couples MAPK Signalling with Early Gene Induction and Cardiac Hypertrophy
Cells, 11 (4)
DOI 10.3390/cells11040604, PubMed 35203255 -
Integrin α11β1 and syndecan-4 dual receptor ablation attenuate cardiac hypertrophy in the pressure overloaded heart
Am J Physiol Heart Circ Physiol, 322 (6), H1057-H1071
DOI 10.1152/ajpheart.00635.2021, PubMed 35522553 -
ADAMTSL3 knock-out mice develop cardiac dysfunction and dilatation with increased TGFβ signalling after pressure overload
Commun Biol, 5 (1), 1392
DOI 10.1038/s42003-022-04361-1, PubMed 36539599 -
Modulation of Ricin Intoxication by the Autophagy Inhibitor EACC
Toxins (Basel), 14 (5)
DOI 10.3390/toxins14050360, PubMed 35622606 -
Prolonged β-adrenergic stimulation disperses ryanodine receptor clusters in cardiomyocytes and has implications for heart failure
Elife, 11
DOI 10.7554/eLife.77725, PubMed 35913125 -
The effects of geometry on stiffness measurements in high-field magnetic resonance elastography: A study on rodent cardiac phantoms
J Mech Behav Biomed Mater, 133, 105302
DOI 10.1016/j.jmbbm.2022.105302, PubMed 35688038 -
Discordant Ca2+ release in cardiac myocytes: characterization and susceptibility to pharmacological RyR2 modulation
Pflugers Arch, 474 (6), 625-636
DOI 10.1007/s00424-022-02678-8, PubMed 35235009 -
The female syndecan-4-/- heart has smaller cardiomyocytes, augmented insulin/pSer473-Akt/pSer9-GSK-3β signaling, and lowered SCOP, pThr308-Akt/Akt and GLUT4 levels
Front Cell Dev Biol, 10, 908126
DOI 10.3389/fcell.2022.908126, PubMed 36092718 -
Early cardiac-chamber-specific fingerprints in heart failure with preserved ejection fraction detected by FTIR and Raman spectroscopic techniques
Sci Rep, 12 (1), 3440
DOI 10.1038/s41598-022-07390-2, PubMed 35236899 -
Impact of delayed type hypersensitivity arthritis on development of heart failure by aortic constriction in mice
PLoS One, 17 (1), e0262821
DOI 10.1371/journal.pone.0262821, PubMed 35077491 -
Extreme altitude induces divergent mass reduction of right and left ventricle in mountain climbers
Physiol Rep, 10 (3), e15184
DOI 10.14814/phy2.15184, PubMed 35146955 -
Body composition in long-standing juvenile dermatomyositis: associations with disease activity, muscle strength and cardiometabolic measures
Rheumatology (Oxford), 61 (7), 2959-2968
DOI 10.1093/rheumatology/keab805, PubMed 34718443 -
Associations between cardiac and pulmonary involvement in patients with juvenile dermatomyositis-a cross-sectional study
Rheumatol Int, 42 (7), 1213-1220
DOI 10.1007/s00296-021-05071-3, PubMed 34984516 -
Mechanisms of spontaneous Ca2+ release-mediated arrhythmia in a novel 3D human atrial myocyte model: I. Transverse-axial tubule variation
J Physiol, 601 (13), 2655-2683
DOI 10.1113/JP283363, PubMed 36094888 -
Mechanisms of spontaneous Ca2+ release-mediated arrhythmia in a novel 3D human atrial myocyte model: II. Ca2+ -handling protein variation
J Physiol, 601 (13), 2685-2710
DOI 10.1113/JP283602, PubMed 36114707
Publications 2021
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A 4D continuous representation of myocardial velocity fields from tissue phase mapping magnetic resonance imaging
PLoS One, 16 (3), e0247826
DOI 10.1371/journal.pone.0247826, PubMed 33647070 -
Right ventricular involvement in hypertrophic cardiomyopathy: evidence and implications from current literature
Scand Cardiovasc J, 55 (4), 195-204
DOI 10.1080/14017431.2021.1901979, PubMed 33759664 -
Kidney Transplant Recipient Behavior During the Early COVID-19 Pandemic: A National Survey Study in Norway
Kidney Med, 4 (2), 100389
DOI 10.1016/j.xkme.2021.09.006, PubMed 34805967 -
AKAP18δ Anchors and Regulates CaMKII Activity at Phospholamban-SERCA2 and RYR
Circ Res, 130 (1), 27-44
DOI 10.1161/CIRCRESAHA.120.317976, PubMed 34814703 -
Atrial disease and heart failure: the common soil hypothesis proposed by the Heart Failure Association of the European Society of Cardiology
Eur Heart J (in press)
DOI 10.1093/eurheartj/ehab834, PubMed 34875053 -
Atrial Natriuretic Peptide31-67: A Novel Therapeutic Factor for Cardiovascular Diseases
Front Physiol, 12, 691407
DOI 10.3389/fphys.2021.691407, PubMed 34305645 -
Exercise Training Stabilizes RyR2-Dependent Ca2+ Release in Post-infarction Heart Failure
Front Cardiovasc Med, 7, 623922
DOI 10.3389/fcvm.2020.623922, PubMed 33569394 -
Cardiac Transverse Tubules in Physiology and Heart Failure
Annu Rev Physiol, 84, 229-255
DOI 10.1146/annurev-physiol-061121-040148, PubMed 34780259 -
Sarcoplasmic Reticulum Calcium Release Is Required for Arrhythmogenesis in the Mouse
Front Physiol, 12, 744730
DOI 10.3389/fphys.2021.744730, PubMed 34712150 -
Etiology-Dependent Impairment of Diastolic Cardiomyocyte Calcium Homeostasis in Heart Failure With Preserved Ejection Fraction
J Am Coll Cardiol, 77 (4), 405-419
DOI 10.1016/j.jacc.2020.11.044, PubMed 33509397 -
Phospholamban antisense oligonucleotides improve cardiac function in murine cardiomyopathy
Nat Commun, 12 (1), 5180
DOI 10.1038/s41467-021-25439-0, PubMed 34462437 -
Insights into the modulation of the interferon response and NAD+ in the context of COVID-19
Int Rev Immunol, 41 (4), 464-474
DOI 10.1080/08830185.2021.1961768, PubMed 34378474 -
Nanoscale Organisation of Ryanodine Receptors and Junctophilin-2 in the Failing Human Heart
Front Physiol, 12, 724372
DOI 10.3389/fphys.2021.724372, PubMed 34690801 -
A possible role for HLA-G in development of uteroplacental acute atherosis in preeclampsia
J Reprod Immunol, 144, 103284
DOI 10.1016/j.jri.2021.103284, PubMed 33578175 -
Distorted assessment of left atrial size by echocardiography in patients with increased aortic root diameter
Egypt Heart J, 73 (1), 55
DOI 10.1186/s43044-021-00177-2, PubMed 34173898 -
Synchrony of sarcomeric movement regulates left ventricular pump function in the in vivo beating mouse heart
J Gen Physiol, 153 (11)
DOI 10.1085/jgp.202012860, PubMed 34605861 -
Circulating microRNAs May Serve as Biomarkers for Hypertensive Emergency End-Organ Injuries and Address Underlying Pathways in an Animal Model
Front Cardiovasc Med, 7, 626699
DOI 10.3389/fcvm.2020.626699, PubMed 33644125 -
Bone mineral density and explanatory factors in children and adults with juvenile dermatomyositis at long term follow-up; a cross sectional study
Pediatr Rheumatol Online J, 19 (1), 56
DOI 10.1186/s12969-021-00543-z, PubMed 33902632 -
The small molecule SERCA activator CDN1163 increases energy metabolism in human skeletal muscle cells
Curr Res Pharmacol Drug Discov, 2, 100060
DOI 10.1016/j.crphar.2021.100060, PubMed 34909682 -
Performance of a Novel Research-Use-Only Secretoneurin ELISA in Patients with Suspected Acute Coronary Syndrome: Comparison with an Established Secretoneurin Radioimmunoassay
Cardiology, 146 (5), 566-574
DOI 10.1159/000517444, PubMed 34284402 -
Sacubitril/valsartan ameliorates cardiac hypertrophy and preserves diastolic function in cardiac pressure overload
ESC Heart Fail, 8 (2), 918-927
DOI 10.1002/ehf2.13177, PubMed 33497525 -
An mRNA assay system demonstrates proteasomal-specific degradation contributes to cardiomyopathic phospholamban null mutation
Mol Med, 27 (1), 102
DOI 10.1186/s10020-021-00362-8, PubMed 34496741 -
Circulating MicroRNA-210 Concentrations in Patients with Acute Heart Failure: Data from the Akershus Cardiac Examination 2 Study
Clin Chem, 67 (6), 889-898
DOI 10.1093/clinchem/hvab030, PubMed 33783502 -
The extracellular matrix glycoprotein ADAMTSL2 is increased in heart failure and inhibits TGFβ signalling in cardiac fibroblasts
Sci Rep, 11 (1), 19757
DOI 10.1038/s41598-021-99032-2, PubMed 34611183 -
CaMKII inhibition has dual effects on spontaneous Ca2+ release and Ca2+ alternans in ventricular cardiomyocytes from mice with a gain-of-function RyR2 mutation
Am J Physiol Heart Circ Physiol, 321 (2), H446-H460
DOI 10.1152/ajpheart.00011.2021, PubMed 34270372 -
The oxidation-resistant CaMKII-MM281/282VV mutation does not prevent arrhythmias in CPVT1
Physiol Rep, 9 (18), e15030
DOI 10.14814/phy2.15030, PubMed 34558218 -
The Physiology and Pathophysiology of T-Tubules in the Heart
Front Physiol, 12, 718404
DOI 10.3389/fphys.2021.718404, PubMed 34566684 -
Corrigendum: The Physiology and Pathophysiology of T-Tubules in the Heart
Front Physiol, 12, 790227
DOI 10.3389/fphys.2021.790227, PubMed 34764889 -
Cerebral perfusion and metabolism with mean arterial pressure 90 vs. 60 mmHg in a porcine post cardiac arrest model with and without targeted temperature management
Resuscitation, 167, 251-260
DOI 10.1016/j.resuscitation.2021.06.011, PubMed 34166747 -
Levosimendan Versus Milrinone and Release of Myocardial Biomarkers After Pediatric Cardiac Surgery: Post Hoc Analysis of Clinical Trial Data
Pediatr Crit Care Med, 22 (7), e402-e409
DOI 10.1097/PCC.0000000000002712, PubMed 33739957 -
Design of a Proteolytically Stable Sodium-Calcium Exchanger 1 Activator Peptide for In Vivo Studies
Front Pharmacol, 12, 638646
DOI 10.3389/fphar.2021.638646, PubMed 34163352 -
Role of t-tubule remodeling on mechanisms of abnormal calcium release during heart failure development in canine ventricle
Am J Physiol Heart Circ Physiol, 320 (4), H1658-H1669
DOI 10.1152/ajpheart.00946.2020, PubMed 33635163 -
Phosphatidylinositol-4,5-Bisphosphate Binding to Amphiphysin-II Modulates T-Tubule Remodeling: Implications for Heart Failure
Front Physiol, 12, 782767
DOI 10.3389/fphys.2021.782767, PubMed 35002765 -
The Angiotensin II Type 1(AT1) Receptor and Cardiac Hypertrophy: Did We Have It Wrong All Along?
J Cardiovasc Pharmacol, 77 (5), 531-535
DOI 10.1097/FJC.0000000000000999, PubMed 33657051 -
How to generate graded spinal cord injuries in swine - tools and procedures
Dis Model Mech, 14 (8)
DOI 10.1242/dmm.049053, PubMed 34464444 -
Biological variation of secretoneurin; a novel cardiovascular biomarker implicated in arrhythmogenesis
Clin Biochem, 98, 74-77
DOI 10.1016/j.clinbiochem.2021.09.014, PubMed 34624255
Publications 2020
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Generation of a novel mouse strain with fibroblast-specific expression of Cre recombinase
Matrix Biol Plus, 8, 100045
DOI 10.1016/j.mbplus.2020.100045, PubMed 33543038 -
Cardioprotective Effects of the Novel Compound Vastiras in a Preclinical Model of End-Organ Damage
Hypertension, 75 (5), 1195-1204
DOI 10.1161/HYPERTENSIONAHA.120.14704, PubMed 32200677 -
Untangling the Interplay Between Mitochondrial Fission and NF-κB Signaling in Endothelial Inflammation
Hypertension, 76 (1), 23-25
DOI 10.1161/HYPERTENSIONAHA.120.14854, PubMed 32520615 -
High-sensitivity cardiac troponin T and N-terminal pro-B-type natriuretic peptide in acute heart failure: Data from the ACE 2 study
Clin Biochem, 88, 30-36
DOI 10.1016/j.clinbiochem.2020.11.009, PubMed 33245872 -
Renal sympathetic denervation lowers systemic vascular resistance in true treatment-resistant hypertension
Blood Press, 30 (1), 31-40
DOI 10.1080/08037051.2020.1789446, PubMed 32633141 -
Functional and Structural Adaptations of Skeletal Muscle in Long-Term Juvenile Dermatomyositis: A Controlled Cross-Sectional Study
Arthritis Rheumatol, 72 (5), 837-848
DOI 10.1002/art.41174, PubMed 31746550 -
Macrophage responses associated with COVID-19: A pharmacological perspective
Eur J Pharmacol, 887, 173547
DOI 10.1016/j.ejphar.2020.173547, PubMed 32919938 -
Live Tissue Training on Anesthetized Pigs for Air Ambulance Crews
Air Med J, 40 (1), 60-64
DOI 10.1016/j.amj.2020.10.003, PubMed 33455629 -
Identification of novel genetic variants associated with cardiorespiratory fitness
Prog Cardiovasc Dis, 63 (3), 341-349
DOI 10.1016/j.pcad.2020.02.001, PubMed 32035127 -
Analysis of right ventricular mass from magnetic resonance imaging data: a simple post-processing algorithm for correction of partial-volume effects
Am J Physiol Heart Circ Physiol, 320 (2), H912-H922
DOI 10.1152/ajpheart.00494.2020, PubMed 33337965 -
Human ISL1+ Ventricular Progenitors Self-Assemble into an In Vivo Functional Heart Patch and Preserve Cardiac Function Post Infarction
Mol Ther, 29 (1), 409
DOI 10.1016/j.ymthe.2020.11.015, PubMed 33296664 -
Intensive smolt production is associated with deviating cardiac morphology in Atlantic salmon (Salmo salar L.)
Aquaculture, 529, 735615
DOI 10.1016/j.aquaculture.2020.735615 -
Assessment of cardiac structure and function in a murine model of temporal lobe epilepsy
Epilepsy Res, 161, 106300
DOI 10.1016/j.eplepsyres.2020.106300, PubMed 32126491 -
Sex-based differences in myocardial infarction-induced kidney damage following cigarette smoking exposure: more renal protection in premenopausal female mice
Biosci Rep, 40 (6)
DOI 10.1042/BSR20193229, PubMed 32519752 -
Quantifying left ventricular function in heart failure: What makes a clinically valuable parameter?
Prog Cardiovasc Dis, 63 (5), 552-560
DOI 10.1016/j.pcad.2020.05.007, PubMed 32502560 -
The Association Between Circulating Inflammatory Markers and the Progression of Alzheimer Disease in Norwegian Memory Clinic Patients With Mild Cognitive Impairment or Dementia
Alzheimer Dis Assoc Disord, 34 (1), 47-53
DOI 10.1097/WAD.0000000000000342, PubMed 31414991 -
Syndecan-4 Protects the Heart From the Profibrotic Effects of Thrombin-Cleaved Osteopontin
J Am Heart Assoc, 9 (3), e013518
DOI 10.1161/JAHA.119.013518, PubMed 32000579 -
Stretch modulation of cardiac contractility: importance of myocyte calcium during the slow force response
Biophys Rev, 12 (1), 135-142
DOI 10.1007/s12551-020-00615-6, PubMed 31939110 -
Real-Time In Vivo Imaging of Mouse Left Ventricle Reveals Fluctuating Movements of the Intercalated Discs
Nanomaterials (Basel), 10 (3)
DOI 10.3390/nano10030532, PubMed 32188039 -
Correlation of Body Weight and Composition With Hepatic Activities of Cytochrome P450 Enzymes
J Pharm Sci, 110 (1), 432-437
DOI 10.1016/j.xphs.2020.10.027, PubMed 33091408 -
A horse of a different colour: distinct mechanisms of HFpEF and HFrEF
J Physiol, 598 (22), 5005-5006
DOI 10.1113/JP280691, PubMed 32985684 -
Absence of NLRP3 Inflammasome in Hematopoietic Cells Reduces Adverse Remodeling After Experimental Myocardial Infarction
JACC Basic Transl Sci, 5 (12), 1210-1224
DOI 10.1016/j.jacbts.2020.09.013, PubMed 33426377 -
Novel associations between cytokines and pulmonary involvement in juvenile dermatomyositis - a cross-sectional study of long-term disease
Rheumatology (Oxford), 59 (8), 1862-1870
DOI 10.1093/rheumatology/kez531, PubMed 31740970 -
Chronic cardiac structural damage, diastolic and systolic dysfunction following acute myocardial injury due to bromine exposure in rats
Arch Toxicol, 95 (1), 179-193
DOI 10.1007/s00204-020-02919-8, PubMed 32979061 -
The Cardiac Syndecan-2 Interactome
Front Cell Dev Biol, 8, 792
DOI 10.3389/fcell.2020.00792, PubMed 32984315 -
Moderate Loss of the Extracellular Matrix Proteoglycan Lumican Attenuates Cardiac Fibrosis in Mice Subjected to Pressure Overload
Cardiology, 145 (3), 187-198
DOI 10.1159/000505318, PubMed 31968347 -
Impact of the Renin-Angiotensin System on the Endothelium in Vascular Dementia: Unresolved Issues and Future Perspectives
Int J Mol Sci, 21 (12)
DOI 10.3390/ijms21124268, PubMed 32560034 -
Sjögren syndrome/scleroderma autoantigen 1 is a direct Tankyrase binding partner in cancer cells
Commun Biol, 3 (1), 123
DOI 10.1038/s42003-020-0851-2, PubMed 32170109 -
Probenecid Improves Cardiac Function in Subjects with a Fontan Circulation and Augments Cardiomyocyte Calcium Homeostasis
Pediatr Cardiol, 41 (8), 1675-1688
DOI 10.1007/s00246-020-02427-7, PubMed 32770262 -
Syndecan-4-/- Mice Have Smaller Muscle Fibers, Increased Akt/mTOR/S6K1 and Notch/HES-1 Pathways, and Alterations in Extracellular Matrix Components
Front Cell Dev Biol, 8, 730
DOI 10.3389/fcell.2020.00730, PubMed 32850844 -
Coupling of the Na+/K+-ATPase to Ankyrin B controls Na+/Ca2+ exchanger activity in cardiomyocytes
Cardiovasc Res, 116 (1), 78-90
DOI 10.1093/cvr/cvz087, PubMed 30949686 -
NLRP3 inflammasome deficiency attenuates metabolic disturbances involving alterations in the gut microbial profile in mice exposed to high fat diet
Sci Rep, 10 (1), 21006
DOI 10.1038/s41598-020-76497-1, PubMed 33273482 -
Nicotinamide adenine dinucleotide: Biosynthesis, consumption and therapeutic role in cardiac diseases
Acta Physiol (Oxf), 231 (3), e13551
DOI 10.1111/apha.13551, PubMed 32853469 -
Hypokalemia Promotes Arrhythmia by Distinct Mechanisms in Atrial and Ventricular Myocytes
Circ Res, 126 (7), 889-906
DOI 10.1161/CIRCRESAHA.119.315641, PubMed 32070187 -
The extracellular juncture domains in the intimin passenger adopt a constitutively extended conformation inducing restraints to its sphere of action
Sci Rep, 10 (1), 21249
DOI 10.1038/s41598-020-77706-7, PubMed 33277518
Publications 2019
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Editorial: Cardiac Microvascular Endothelium Contribution to Cardiac Myocyte Growth, Structure, and Contractile Function
Front Cardiovasc Med, 6, 130
DOI 10.3389/fcvm.2019.00130, PubMed 31552274 -
Association Between Nailfold Capillary Density and Pulmonary and Cardiac Involvement in Medium to Longstanding Juvenile Dermatomyositis
Arthritis Care Res (Hoboken), 71 (4), 492-497
DOI 10.1002/acr.23687, PubMed 29953739 -
Cardiorespiratory fitness in long-term juvenile dermatomyositis: a controlled, cross-sectional study of active/inactive disease
Rheumatology (Oxford), 58 (3), 492-501
DOI 10.1093/rheumatology/key342, PubMed 30508195 -
Cardiovascular rEmodelling in living kidNey donorS with reduced glomerular filtration rate: rationale and design of the CENS study
Blood Press, 29 (2), 123-134
DOI 10.1080/08037051.2019.1684817, PubMed 31718316 -
Circulating secretoneurin concentrations in patients with moderate to severe aortic stenosis
Clin Biochem, 71, 17-23
DOI 10.1016/j.clinbiochem.2019.06.008, PubMed 31228433 -
Circulating Secretoneurin Concentrations After Cardiac Surgery: Data From the FINNish Acute Kidney Injury Heart Study
Crit Care Med, 47 (5), e412-e419
DOI 10.1097/CCM.0000000000003670, PubMed 30730440 -
A Matched-Filter-Based Algorithm for Subcellular Classification of T-System in Cardiac Tissues
Biophys J, 116 (8), 1386-1393
DOI 10.1016/j.bpj.2019.03.010, PubMed 30979553 -
Towards better definition, quantification and treatment of fibrosis in heart failure. A scientific roadmap by the Committee of Translational Research of the Heart Failure Association (HFA) of the European Society of Cardiology
Eur J Heart Fail, 21 (3), 272-285
DOI 10.1002/ejhf.1406, PubMed 30714667 -
Integrin α11 cytoplasmic tail is required for FAK activation to initiate 3D cell invasion and ERK-mediated cell proliferation
Sci Rep, 9 (1), 15283
DOI 10.1038/s41598-019-51689-6, PubMed 31653900 -
Regional right ventricular function in rats: a novel magnetic resonance imaging method for measurement of right ventricular strain
Am J Physiol Heart Circ Physiol, 318 (1), H143-H153
DOI 10.1152/ajpheart.00357.2019, PubMed 31774693 -
Acute atherosis of decidua basalis; characterization of spiral arteries, endothelial status and activation
Placenta, 82, 10-16
DOI 10.1016/j.placenta.2019.04.006, PubMed 31174621 -
Reply from M. Frisk, D. B. Lipsett and W. E. Louch
J Physiol, 597 (11), 2967-2968
DOI 10.1113/JP278067, PubMed 31021407 -
Catalyzing Transcriptomics Research in Cardiovascular Disease: The CardioRNA COST Action CA17129
Noncoding RNA, 5 (2)
DOI 10.3390/ncrna5020031, PubMed 30934986 -
Remodeling of secretory lysosomes during education tunes functional potential in NK cells
Nat Commun, 10 (1), 514
DOI 10.1038/s41467-019-08384-x, PubMed 30705279 -
Lymphocyte characterization of decidua basalis spiral arteries with acute atherosis in preeclamptic and normotensive pregnancies
J Reprod Immunol, 132, 42-48
DOI 10.1016/j.jri.2019.03.003, PubMed 30928772 -
Annual decline in forced expiratory volume and airway inflammatory cells and mediators in a general population-based sample
BMC Pulm Med, 19 (1), 90
DOI 10.1186/s12890-018-0765-7, PubMed 31072364 -
Cardiomyocyte substructure reverts to an immature phenotype during heart failure
J Physiol, 597 (7), 1833-1853
DOI 10.1113/JP277273, PubMed 30707448 -
Channel surfing: new insights into plasticity of excitation-contraction coupling
J Physiol, 597 (8), 2119-2120
DOI 10.1113/JP277783, PubMed 30854650 -
Multi-nodal nano-actuator pacemaker for energy-efficient stimulation of cardiomyocytes
Nano Commun.Netw., 22, 100270
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The cardiac syndecan-4 interactome reveals a role for syndecan-4 in nuclear translocation of muscle LIM protein (MLP)
J Biol Chem, 294 (22), 8717-8731
DOI 10.1074/jbc.RA118.006423, PubMed 30967474 -
Accelerated magnetic resonance imaging tissue phase mapping of the rat myocardium using compressed sensing with iterative soft-thresholding
PLoS One, 14 (7), e0218874
DOI 10.1371/journal.pone.0218874, PubMed 31276508 -
The extracellular matrix proteoglycan lumican improves survival and counteracts cardiac dilatation and failure in mice subjected to pressure overload
Sci Rep, 9 (1), 9206
DOI 10.1038/s41598-019-45651-9, PubMed 31235849 -
Secretoneurin Is an Endogenous Calcium/Calmodulin-Dependent Protein Kinase II Inhibitor That Attenuates Ca2+-Dependent Arrhythmia
Circ Arrhythm Electrophysiol, 12 (4), e007045
DOI 10.1161/CIRCEP.118.007045, PubMed 30943765 -
Regional diastolic dysfunction in post-infarction heart failure: role of local mechanical load and SERCA expression
Cardiovasc Res, 115 (4), 752-764
DOI 10.1093/cvr/cvy257, PubMed 30351410 -
Increased Complement Factor B and Bb Levels Are Associated with Mortality in Patients with Severe Aortic Stenosis
J Immunol, 203 (7), 1973-1980
DOI 10.4049/jimmunol.1801244, PubMed 31492744 -
Three-Dimensional and Chemical Mapping of Intracellular Signaling Nanodomains in Health and Disease with Enhanced Expansion Microscopy
ACS Nano, 13 (2), 2143-2157
DOI 10.1021/acsnano.8b08742, PubMed 30715853 -
Remodeling Promotes Proarrhythmic Disruption of Calcium Homeostasis in Failing Atrial Myocytes
Biophys J, 118 (2), 476-491
DOI 10.1016/j.bpj.2019.12.012, PubMed 31889516 -
Evidence for heterogeneous subsarcolemmal Na+ levels in rat ventricular myocytes
Am J Physiol Heart Circ Physiol, 316 (5), H941-H957
DOI 10.1152/ajpheart.00637.2018, PubMed 30657726 -
NLRP3 Inflammasome Promotes Myocardial Remodeling During Diet-Induced Obesity
Front Immunol, 10, 1621
DOI 10.3389/fimmu.2019.01621, PubMed 31379826 -
Yin Yang 1 Suppresses Dilated Cardiomyopathy and Cardiac Fibrosis Through Regulation of Bmp7 and Ctgf
Circ Res, 125 (9), 834-846
DOI 10.1161/CIRCRESAHA.119.314794, PubMed 31495264 -
Potassium infusion increases the likelihood of conversion of recent-onset atrial fibrillation-A single-blinded, randomized clinical trial
Am Heart J, 221, 114-124
DOI 10.1016/j.ahj.2019.12.014, PubMed 31986288 -
Electrolyte imbalances in an unselected population in an emergency department: A retrospective cohort study
PLoS One, 14 (4), e0215673
DOI 10.1371/journal.pone.0215673, PubMed 31022222 -
The Effect of Levosimendan Versus Milrinone on the Occurrence Rate of Acute Kidney Injury Following Congenital Heart Surgery in Infants: A Randomized Clinical Trial
Pediatr Crit Care Med, 20 (10), 947-956
DOI 10.1097/PCC.0000000000002017, PubMed 31274775 -
Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin
Sci Transl Med, 11 (476)
DOI 10.1126/scitranslmed.aat1199, PubMed 30674652 -
The continuous heart failure spectrum: moving beyond an ejection fraction classification
Eur Heart J, 40 (26), 2155-2163
DOI 10.1093/eurheartj/ehz158, PubMed 30957868 -
Caspase-1 induces smooth muscle cell growth in hypoxia-induced pulmonary hypertension
Am J Physiol Lung Cell Mol Physiol, 316 (6), L999-L1012
DOI 10.1152/ajplung.00322.2018, PubMed 30908936 -
Effect on Cardiac Function of Longstanding Juvenile-onset Mixed Connective Tissue Disease: A Controlled Study
J Rheumatol, 46 (7), 739-747
DOI 10.3899/jrheum.180526, PubMed 30877222 -
Cancer-associated fibroblasts in desmoplastic tumors: emerging role of integrins
Semin Cancer Biol, 62, 166-181
DOI 10.1016/j.semcancer.2019.08.004, PubMed 31415910 -
Protection of axonal integrity with 48 or 72 h of cerebral hypothermia in near-term fetal sheep
Pediatr Res, 88 (1), 48-56
DOI 10.1038/s41390-019-0475-8, PubMed 31234193 -
STAT3 and Endothelial Cell-Cardiomyocyte Dialog in Cardiac Remodeling
Front Cardiovasc Med, 6, 50
DOI 10.3389/fcvm.2019.00050, PubMed 31069236 -
Development of a Multimodal Apparatus to Generate Biomechanically Reproducible Spinal Cord Injuries in Large Animals
Front Neurol, 10, 223
DOI 10.3389/fneur.2019.00223, PubMed 30941086
Publications 2018
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Bromine inhalation mimics ischemia-reperfusion cardiomyocyte injury and calpain activation in rats
Am J Physiol Heart Circ Physiol, 316 (1), H212-H223
DOI 10.1152/ajpheart.00652.2017, PubMed 30379573 -
Conflicting vascular and metabolic impact of the IL-33/sST2 axis
Cardiovasc Res, 114 (12), 1578-1594
DOI 10.1093/cvr/cvy166, PubMed 29982301 -
In Silico Analysis of Differential Gene Expression in Three Common Rat Models of Diastolic Dysfunction
Front Cardiovasc Med, 5, 11
DOI 10.3389/fcvm.2018.00011, PubMed 29556499 -
The extracellular matrix proteoglycan fibromodulin is upregulated in clinical and experimental heart failure and affects cardiac remodeling
PLoS One, 13 (7), e0201422
DOI 10.1371/journal.pone.0201422, PubMed 30052659 -
Diagnostic and prognostic properties of procalcitonin in patients with acute dyspnea: Data from the ACE 2 Study
Clin Biochem, 59, 62-68
DOI 10.1016/j.clinbiochem.2018.07.006, PubMed 30028971 -
Bringing European physiologists together
Acta Physiol (Oxf), 222 (4), e13043
DOI 10.1111/apha.13043, PubMed 29377580 -
TBC1D5 controls the GTPase cycle of Rab7b
J Cell Sci, 131 (17)
DOI 10.1242/jcs.216630, PubMed 30111580 -
Sweet, yet underappreciated: Proteoglycans and extracellular matrix remodeling in heart disease
Matrix Biol, 75-76, 286-299
DOI 10.1016/j.matbio.2018.01.001, PubMed 29337052 -
Arrhythmia initiation in catecholaminergic polymorphic ventricular tachycardia type 1 depends on both heart rate and sympathetic stimulation
PLoS One, 13 (11), e0207100
DOI 10.1371/journal.pone.0207100, PubMed 30399185 -
O-GlcNAc site-mapping of liver X receptor-α and O-GlcNAc transferase
Biochem Biophys Res Commun, 499 (2), 354-360
DOI 10.1016/j.bbrc.2018.03.164, PubMed 29577901 -
Human ISL1+ Ventricular Progenitors Self-Assemble into an In Vivo Functional Heart Patch and Preserve Cardiac Function Post Infarction
Mol Ther, 26 (7), 1644-1659
DOI 10.1016/j.ymthe.2018.02.012, PubMed 29606507 -
STIM1 R304W causes muscle degeneration and impaired platelet activation in mice
Cell Calcium, 76, 87-100
DOI 10.1016/j.ceca.2018.10.001, PubMed 30390422 -
IL-33 (Interleukin 33)/sST2 Axis in Hypertension and Heart Failure
Hypertension, 72 (4), 818-828
DOI 10.1161/HYPERTENSIONAHA.118.11157, PubMed 30354724 -
The combination of maternal KIR-B and fetal HLA-C2 is associated with decidua basalis acute atherosis in pregnancies with preeclampsia
J Reprod Immunol, 129, 23-29
DOI 10.1016/j.jri.2018.07.005, PubMed 30055414 -
Dyadic Plasticity in Cardiomyocytes
Front Physiol, 9, 1773
DOI 10.3389/fphys.2018.01773, PubMed 30618792 -
Cerebral blood flow alteration following acute myocardial infarction in mice
Biosci Rep, 38 (5)
DOI 10.1042/BSR20180382, PubMed 30061176 -
Ryanodine receptor dispersion disrupts Ca2+ release in failing cardiac myocytes
Elife, 7
DOI 10.7554/eLife.39427, PubMed 30375974 -
A novel method for high precision aortic constriction that allows for generation of specific cardiac phenotypes in mice
Cardiovasc Res, 114 (12), 1680-1690
DOI 10.1093/cvr/cvy141, PubMed 29878127 -
Classical Cardiovascular Risk Markers in Pregnancy and Associations to Uteroplacental Acute Atherosis
Hypertension, 72 (3), 695-702
DOI 10.1161/HYPERTENSIONAHA.118.10964, PubMed 30354752 -
Patterns of Invasive Growth in Malignant Gliomas-The Hippocampus Emerges as an Invasion-Spared Brain Region
Neoplasia, 20 (7), 643-656
DOI 10.1016/j.neo.2018.04.001, PubMed 29793116 -
Heart failure and diabetes: metabolic alterations and therapeutic interventions: a state-of-the-art review from the Translational Research Committee of the Heart Failure Association-European Society of Cardiology
Eur Heart J, 39 (48), 4243-4254
DOI 10.1093/eurheartj/ehy596, PubMed 30295797 -
Prognostic and diagnostic significance of mid-regional pro-atrial natriuretic peptide in acute exacerbation of chronic obstructive pulmonary disease and acute heart failure: data from the ACE 2 Study
Biomarkers, 23 (7), 654-663
DOI 10.1080/1354750X.2018.1474258, PubMed 29733687 -
Auto-antibodies against the angiotensin II type I receptor in women with uteroplacental acute atherosis and preeclampsia at delivery and several years postpartum
J Reprod Immunol, 128, 23-29
DOI 10.1016/j.jri.2018.05.008, PubMed 29843114 -
3D dSTORM imaging reveals novel detail of ryanodine receptor localization in rat cardiac myocytes
J Physiol, 597 (2), 399-418
DOI 10.1113/JP277360, PubMed 30412283 -
OGT (O-GlcNAc Transferase) Selectively Modifies Multiple Residues Unique to Lamin A
Cells, 7 (5)
DOI 10.3390/cells7050044, PubMed 29772801 -
Hypokalemia-Induced Arrhythmias and Heart Failure: New Insights and Implications for Therapy
Front Physiol, 9, 1500
DOI 10.3389/fphys.2018.01500, PubMed 30464746 -
Contractile responses to endothelin-1 are regulated by PKC phosphorylation of cardiac myosin binding protein-C in rat ventricular myocytes
J Mol Cell Cardiol, 117, 1-18
DOI 10.1016/j.yjmcc.2018.02.012, PubMed 29470978 -
A fundamental catalytic difference between zinc and manganese dependent enzymes revealed in a bacterial isatin hydrolase
Sci Rep, 8 (1), 13104
DOI 10.1038/s41598-018-31259-y, PubMed 30166577 -
Haemodynamic outcomes during piston-based mechanical CPR with or without active decompression in a porcine model of cardiac arrest
Scand J Trauma Resusc Emerg Med, 26 (1), 31
DOI 10.1186/s13049-018-0496-z, PubMed 29690910 -
Structural Origin of Metal Specificity in Isatin Hydrolase from Labrenzia aggregata Investigated by Computer Simulations
Chemistry, 24 (20), 5074-5077
DOI 10.1002/chem.201705159, PubMed 29243856 -
Associations between Cytokine Levels and CYP3A4 Phenotype in Patients with Rheumatoid Arthritis
Drug Metab Dispos, 46 (10), 1384-1389
DOI 10.1124/dmd.118.082065, PubMed 29991576
Publications 2017
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Wnt5a is associated with right ventricular dysfunction and adverse outcome in dilated cardiomyopathy
Sci Rep, 7 (1), 3490
DOI 10.1038/s41598-017-03625-9, PubMed 28615692 -
Wnt5a is elevated in heart failure and affects cardiac fibroblast function
J Mol Med (Berl), 95 (7), 767-777
DOI 10.1007/s00109-017-1529-1, PubMed 28357477 -
Targeting Obesity and Diabetes to Treat Heart Failure with Preserved Ejection Fraction
Front Endocrinol (Lausanne), 8, 160
DOI 10.3389/fendo.2017.00160, PubMed 28769873 -
The crystal structure of the regulatory domain of the human sodium-driven chloride/bicarbonate exchanger
Sci Rep, 7 (1), 12131
DOI 10.1038/s41598-017-12409-0, PubMed 28935959 -
Noninvasive stratification of postinfarction rats based on the degree of cardiac dysfunction using magnetic resonance imaging and echocardiography
Am J Physiol Heart Circ Physiol, 312 (5), H932-H942
DOI 10.1152/ajpheart.00668.2016, PubMed 28188213 -
Submaximal Exercise Capacity in Juvenile Dermatomyositis after Longterm Disease: The Contribution of Muscle, Lung, and Heart Involvement
J Rheumatol, 44 (6), 827-834
DOI 10.3899/jrheum.160997, PubMed 28365577 -
Factor VII deficiency: Unveiling the cellular and molecular mechanisms underlying three model alterations of the enzyme catalytic domain
Biochim Biophys Acta Mol Basis Dis, 1864 (3), 660-667
DOI 10.1016/j.bbadis.2017.12.016, PubMed 29246447 -
Enhanced liver fibrosis test predicts transplant-free survival in primary sclerosing cholangitis, a multi-centre study
Liver Int, 37 (10), 1554-1561
DOI 10.1111/liv.13402, PubMed 28267887 -
Toll-Like Receptor 9 Promotes Survival in SERCA2a KO Heart Failure Mice
Mediators Inflamm, 2017, 9450439
DOI 10.1155/2017/9450439, PubMed 28490840 -
Species-Dependent Mechanisms of Cardiac Arrhythmia: A Cellular Focus
Clin Med Insights Cardiol, 11, 1179546816686061
DOI 10.1177/1179546816686061, PubMed 28469490 -
Regional Dysfunction After Myocardial Infarction in Rats
Circ Cardiovasc Imaging, 10 (9)
DOI 10.1161/CIRCIMAGING.116.005997, PubMed 28838960 -
A c-Myb mutant causes deregulated differentiation due to impaired histone binding and abrogated pioneer factor function
Nucleic Acids Res, 45 (13), 7681-7696
DOI 10.1093/nar/gkx364, PubMed 28472346 -
Compensatory and decompensatory alterations in cardiomyocyte Ca2+ dynamics in hearts with diastolic dysfunction following aortic banding
J Physiol, 595 (12), 3867-3889
DOI 10.1113/JP273879, PubMed 28542952 -
Mechanical regulation of cardiac fibroblast profibrotic phenotypes
Mol Biol Cell, 28 (14), 1871-1882
DOI 10.1091/mbc.E17-01-0014, PubMed 28468977 -
The Soft- and Hard-Heartedness of Cardiac Fibroblasts: Mechanotransduction Signaling Pathways in Fibrosis of the Heart
J Clin Med, 6 (5)
DOI 10.3390/jcm6050053, PubMed 28534817 -
Gene Transfer in Isolated Adult Cardiomyocytes
Methods Mol Biol, 1521, 169-182
DOI 10.1007/978-1-4939-6588-5_11, PubMed 27910048 -
B-type natriuretic peptide overexpression ameliorates hepatorenal fibrocystic disease in a rat model of polycystic kidney disease
Kidney Int, 92 (3), 657-668
DOI 10.1016/j.kint.2017.02.017, PubMed 28416225 -
Bigger is not better: cortisol-induced cardiac growth and dysfunction in salmonids
J Exp Biol, 220 (Pt 14), 2545-2553
DOI 10.1242/jeb.135046, PubMed 28476893 -
Genome-wide profiling of DNA 5-hydroxymethylcytosine during rat Sertoli cell maturation
Cell Discov, 3, 17013
DOI 10.1038/celldisc.2017.13, PubMed 28529766 -
Lower than expected burden of premature ventricular contractions impairs myocardial function
ESC Heart Fail, 4 (4), 585-594
DOI 10.1002/ehf2.12180, PubMed 29154430 -
T-tubular collagen: a new player in mechanosensing and disease?
Cardiovasc Res, 113 (8), 839-840
DOI 10.1093/cvr/cvx091, PubMed 28481973 -
Mapping the in vitro interactome of cardiac sodium (Na+ )-calcium (Ca2+ ) exchanger 1 (NCX1)
Proteomics, 17 (17-18)
DOI 10.1002/pmic.201600417, PubMed 28755400 -
Cushing's syndrome mutant PKAL205R exhibits altered substrate specificity
FEBS Lett, 591 (3), 459-467
DOI 10.1002/1873-3468.12562, PubMed 28100013 -
Fibroblast growth factor 23 in patients with acute dyspnea: Data from the Akershus Cardiac Examination (ACE) 2 Study
Clin Biochem, 52, 41-47
DOI 10.1016/j.clinbiochem.2017.10.015, PubMed 29074091 -
Studying dyadic structure-function relationships: a review of current modeling approaches and new insights into Ca2+ (mis)handling
Clin Med Insights Cardiol, 11, 1179546817698602
DOI 10.1177/1179546817698602, PubMed 28469494 -
Regulation of Cardiomyocyte T-Tubular Structure: Opportunities for Therapy
Curr Heart Fail Rep, 14 (3), 167-178
DOI 10.1007/s11897-017-0329-9, PubMed 28447290 -
Immune markers, diurnal blood pressure profile and cardiac function in virologically suppressed HIV-infected patients
Blood Press, 26 (6), 332-340
DOI 10.1080/08037051.2017.1346459, PubMed 28675304 -
PDE3 inhibition by C-type natriuretic peptide-induced cGMP enhances cAMP-mediated signaling in both non-failing and failing hearts
Eur J Pharmacol, 812, 174-183
DOI 10.1016/j.ejphar.2017.07.014, PubMed 28697992 -
Circulating chromogranin B levels in patients with acute respiratory failure: data from the FINNALI Study
Biomarkers, 22 (8), 775-781
DOI 10.1080/1354750X.2016.1269200, PubMed 28049363 -
The Notch Ligands DLL1 and Periostin Are Associated with Symptom Severity and Diastolic Function in Dilated Cardiomyopathy
J Cardiovasc Transl Res, 10 (4), 401-410
DOI 10.1007/s12265-017-9748-y, PubMed 28474304 -
NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture
Cell Rep, 18 (1), 82-92
DOI 10.1016/j.celrep.2016.12.009, PubMed 28052262 -
Glycosylated Chromogranin A in Heart Failure: Implications for Processing and Cardiomyocyte Calcium Homeostasis
Circ Heart Fail, 10 (2)
DOI 10.1161/CIRCHEARTFAILURE.116.003675, PubMed 28209766 -
Glycosylated Chromogranin A: Potential Role in the Pathogenesis of Heart Failure
Curr Heart Fail Rep, 14 (6), 478-488
DOI 10.1007/s11897-017-0360-x, PubMed 28975588 -
Thyroid and Glucocorticoid Hormones Promote Functional T-Tubule Development in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes
Circ Res, 121 (12), 1323-1330
DOI 10.1161/CIRCRESAHA.117.311920, PubMed 28974554 -
Mid-regional pro-adrenomedullin in patients with acute dyspnea: Data from the Akershus Cardiac Examination (ACE) 2 Study
Clin Biochem, 50 (7-8), 394-400
DOI 10.1016/j.clinbiochem.2016.12.010, PubMed 28065681 -
Heart failure with preserved ejection fraction
Tidsskr. Nor. Laegeforen., 137 (18), 1426-1431 -
Overexpression of integrin α11 induces cardiac fibrosis in mice
Acta Physiol (Oxf), 222 (2)
DOI 10.1111/apha.12932, PubMed 28771943 -
Connective tissue growth factor and bone morphogenetic protein 2 are induced following myocardial ischemia in mice and humans
Scand J Clin Lab Invest, 77 (5), 321-331
DOI 10.1080/00365513.2017.1318447, PubMed 28460577 -
Increased passive stiffness promotes diastolic dysfunction despite improved Ca2+ handling during left ventricular concentric hypertrophy
Cardiovasc Res, 113 (10), 1161-1172
DOI 10.1093/cvr/cvx087, PubMed 28472418 -
Heart failure with preserved ejection fraction
Tidsskr Nor Laegeforen, 137 (18)
DOI 10.4045/tidsskr.16.1068, PubMed 28972354 -
Correlative Single-Molecule Localization Microscopy and Confocal Microscopy
Methods Mol Biol, 1663, 205-217
DOI 10.1007/978-1-4939-7265-4_17, PubMed 28924670 -
Loss-of-activity-mutation in the cardiac chloride-bicarbonate exchanger AE3 causes short QT syndrome
Nat Commun, 8 (1), 1696
DOI 10.1038/s41467-017-01630-0, PubMed 29167417 -
Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications : Bamberg, Germany. 23-25 June, 2017
BMC Pharmacol Toxicol, 18 (Suppl 1), 64
DOI 10.1186/s40360-017-0170-5, PubMed 29035170 -
The autonomic nervous system as a therapeutic target in heart failure: a scientific position statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology
Eur J Heart Fail, 19 (11), 1361-1378
DOI 10.1002/ejhf.921, PubMed 28949064 -
Novel serum and bile protein markers predict primary sclerosing cholangitis disease severity and prognosis
J Hepatol, 66 (6), 1214-1222
DOI 10.1016/j.jhep.2017.01.019, PubMed 28161472 -
Plasma immunological markers in pregnancy and cord blood: A possible link between macrophage chemo-attractants and risk of childhood type 1 diabetes
Am J Reprod Immunol, 79 (3)
DOI 10.1111/aji.12802, PubMed 29266506 -
A combinatorial approach to identify calpain cleavage sites in the Machado-Joseph disease protein ataxin-3
Brain, 140 (5), 1280-1299
DOI 10.1093/brain/awx039, PubMed 28334907 -
Prognostic and diagnostic significance of copeptin in acute exacerbation of chronic obstructive pulmonary disease and acute heart failure: data from the ACE 2 study
Respir Res, 18 (1), 184
DOI 10.1186/s12931-017-0665-z, PubMed 29100503
Publications 2016
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Cardiomyocyte Ca2+ dynamics: clinical perspectives
Scand Cardiovasc J, 50 (2), 65-77
DOI 10.3109/14017431.2015.1136079, PubMed 26729487 -
Overview of the membrane-associated RING-CH (MARCH) E3 ligase family
N Biotechnol, 38 (Pt A), 7-15
DOI 10.1016/j.nbt.2016.12.002, PubMed 27988304 -
Impact of left ventricular remodeling and renal function on 24h-ECG recordings and cardiovascular outcome in elderly hypertensive patients
Eur J Intern Med, 29, 71-7
DOI 10.1016/j.ejim.2016.01.001, PubMed 26781517 -
Low Circulating Levels of Mitochondrial and High Levels of Nuclear DNA Predict Mortality in Chronic Heart Failure
J Card Fail, 22 (10), 823-8
DOI 10.1016/j.cardfail.2016.06.013, PubMed 27349571 -
Increased hypertrophic response with increased mechanical load in skeletal muscles receiving identical activity patterns
Am J Physiol Cell Physiol, 311 (4), C616-C629
DOI 10.1152/ajpcell.00016.2016, PubMed 27488660 -
A semiautomatic method for rapid segmentation of velocity-encoded myocardial magnetic resonance imaging data
Magn Reson Med, 78 (3), 1199-1207
DOI 10.1002/mrm.26486, PubMed 27699840 -
Elevated ventricular wall stress disrupts cardiomyocyte t-tubule structure and calcium homeostasis
Cardiovasc Res, 112 (1), 443-51
DOI 10.1093/cvr/cvw111, PubMed 27226008 -
The calcium-frequency response in the rat ventricular myocyte: an experimental and modelling study
J Physiol, 594 (15), 4193-224
DOI 10.1113/JP272011, PubMed 26916026 -
Using the fluorescent properties of STO-609 as a tool to assist structure-function analyses of recombinant CaMKK2
Biochem Biophys Res Commun, 476 (2), 102-7
DOI 10.1016/j.bbrc.2016.05.045, PubMed 27178209 -
Data for the co-expression and purification of human recombinant CaMKK2 in complex with calmodulin in Escherichia coli
Data Brief, 8, 733-40
DOI 10.1016/j.dib.2016.06.033, PubMed 27508226 -
Exercise training increases protein O-GlcNAcylation in rat skeletal muscle
Physiol Rep, 4 (18)
DOI 10.14814/phy2.12896, PubMed 27664189 -
The Impact of Chronic Glycogen Synthase Kinase-3 Inhibition on Remodeling of Normal and Pre-Diabetic Rat Hearts
Cardiovasc Drugs Ther, 30 (3), 237-46
DOI 10.1007/s10557-016-6665-2, PubMed 27180786 -
The influence of heart failure co-morbidity on high-sensitivity troponin T levels in COPD exacerbation in a prospective cohort study: data from the Akershus cardiac examination (ACE) 2 study
Biomarkers, 21 (2), 173-9
DOI 10.3109/1354750X.2015.1126645, PubMed 26754170 -
The gut microbial profile in patients with primary sclerosing cholangitis is distinct from patients with ulcerative colitis without biliary disease and healthy controls
Gut, 66 (4), 611-619
DOI 10.1136/gutjnl-2015-310500, PubMed 26887816 -
Ca(2+)-Clock-Dependent Pacemaking in the Sinus Node Is Impaired in Mice with a Cardiac Specific Reduction in SERCA2 Abundance
Front Physiol, 7, 197
DOI 10.3389/fphys.2016.00197, PubMed 27313537 -
Syndecans in heart fibrosis
Cell Tissue Res, 365 (3), 539-52
DOI 10.1007/s00441-016-2454-2, PubMed 27411689 -
Exercise training prevents ventricular tachycardia in CPVT1 due to reduced CaMKII-dependent arrhythmogenic Ca2+ release
Cardiovasc Res, 111 (3), 295-306
DOI 10.1093/cvr/cvw095, PubMed 27161030 -
The Heparan Sulfate Proteoglycan Glypican-6 Is Upregulated in the Failing Heart, and Regulates Cardiomyocyte Growth through ERK1/2 Signaling
PLoS One, 11 (10), e0165079
DOI 10.1371/journal.pone.0165079, PubMed 27768722 -
Prognostic Value of Secretoneurin in Patients with Acute Respiratory Failure: Data from the FINNALI Study
Clin Chem, 62 (10), 1380-9
DOI 10.1373/clinchem.2016.258764, PubMed 27540029 -
Prognostic Value of Secretoneurin in Critically Ill Patients With Infections
Crit Care Med, 44 (10), 1882-90
DOI 10.1097/CCM.0000000000001832, PubMed 27414477 -
Beta-Adrenoceptor Stimulation Reveals Ca2+ Waves and Sarcoplasmic Reticulum Ca2+ Depletion in Left Ventricular Cardiomyocytes from Post-Infarction Rats with and without Heart Failure
PLoS One, 11 (4), e0153887
DOI 10.1371/journal.pone.0153887, PubMed 27096943 -
Cardiac involvement in adult and juvenile idiopathic inflammatory myopathies
RMD Open, 2 (2), e000291
DOI 10.1136/rmdopen-2016-000291, PubMed 27752355 -
Three-Directional Evaluation of Mitral Flow in the Rat Heart by Phase-Contrast Cardiovascular Magnetic Resonance
PLoS One, 11 (3), e0150536
DOI 10.1371/journal.pone.0150536, PubMed 26930073 -
Evaluation of four commonly used normalizer genes for the study of decidual gene expression
Placenta, 43, 9-12
DOI 10.1016/j.placenta.2016.04.009, PubMed 27324093 -
The magnesium transporter A is activated by cardiolipin and is highly sensitive to free magnesium in vitro
Elife, 5
DOI 10.7554/eLife.11407, PubMed 26780187 -
The H3K9 dimethyltransferases EHMT1/2 protect against pathological cardiac hypertrophy
J Clin Invest, 127 (1), 335-348
DOI 10.1172/JCI88353, PubMed 27893464 -
Development of a high-affinity peptide that prevents phospholemman (PLM) inhibition of the sodium/calcium exchanger 1 (NCX1)
Biochem J, 473 (15), 2413-23
DOI 10.1042/BCJ20160465, PubMed 27247424 -
Prevalence and Prognostic Significance of Hyponatremia in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Data from the Akershus Cardiac Examination (ACE) 2 Study
PLoS One, 11 (8), e0161232
DOI 10.1371/journal.pone.0161232, PubMed 27529844
Publications 2015
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In juvenile dermatomyositis, heart rate variability is reduced, and associated with both cardiac dysfunction and markers of inflammation: a cross-sectional study median 13.5 years after symptom onset
Rheumatology (Oxford), 55 (3), 535-43
DOI 10.1093/rheumatology/kev376, PubMed 26500284 -
Long-Term Structural and Functional Myocardial Adaptations in Healthy Living Kidney Donors: A Pilot Study
PLoS One, 10 (11), e0142103
DOI 10.1371/journal.pone.0142103, PubMed 26556804 -
Effects of haloperidol and aripiprazole on the human mesolimbic motivational system: A pharmacological fMRI study
Eur Neuropsychopharmacol, 25 (12), 2252-61
DOI 10.1016/j.euroneuro.2015.09.016, PubMed 26476705 -
[Diagnostic accuracy for heart failure – data from the Akershus Cardiac Examination 2 Study]
Tidsskr Nor Laegeforen, 135 (19), 1738-44
DOI 10.4045/tidsskr.14.1174, PubMed 26486668 -
Absence of the inflammasome adaptor ASC reduces hypoxia-induced pulmonary hypertension in mice
Am J Physiol Lung Cell Mol Physiol, 309 (4), L378-87
DOI 10.1152/ajplung.00342.2014, PubMed 26071556 -
Deranged sodium to sudden death
J Physiol, 593 (6), 1331-45
DOI 10.1113/jphysiol.2014.281204, PubMed 25772289 -
Linking ryanodine receptor Ca(2+) leak and Na(+) current in heart: a day in the life of flecainide
Acta Physiol (Oxf), 214 (3), 300-2
DOI 10.1111/apha.12526, PubMed 25976700 -
Sustained Toll-Like Receptor 9 Activation Promotes Systemic and Cardiac Inflammation, and Aggravates Diastolic Heart Failure in SERCA2a KO Mice
PLoS One, 10 (10), e0139715
DOI 10.1371/journal.pone.0139715, PubMed 26461521 -
Psychological distress and mortality in patients with acute dyspnea: data from the Akershus Cardiac Examination (ACE) 2 Study
Gen Hosp Psychiatry, 37 (6), 548-53
DOI 10.1016/j.genhosppsych.2015.07.007, PubMed 26298205 -
Assessment of regional myocardial work in rats
Circ Cardiovasc Imaging, 8 (2), e002695
DOI 10.1161/CIRCIMAGING.114.002695, PubMed 25673647 -
Protein Phosphatase 1c Associated with the Cardiac Sodium Calcium Exchanger 1 Regulates Its Activity by Dephosphorylating Serine 68-phosphorylated Phospholemman
J Biol Chem, 291 (9), 4561-79
DOI 10.1074/jbc.M115.677898, PubMed 26668322 -
Syndecan-4 is a key determinant of collagen cross-linking and passive myocardial stiffness in the pressure-overloaded heart
Cardiovasc Res, 106 (2), 217-26
DOI 10.1093/cvr/cvv002, PubMed 25587045 -
B-Type Natriuretic Peptide Deletion Leads to Progressive Hypertension, Associated Organ Damage, and Reduced Survival: Novel Model for Human Hypertension
Hypertension, 66 (1), 199-210
DOI 10.1161/HYPERTENSIONAHA.115.05610, PubMed 26063669 -
Exhausting treadmill running causes dephosphorylation of sMLC2 and reduced level of myofilament MLCK2 in slow twitch rat soleus muscle
Physiol Rep, 3 (2)
DOI 10.14814/phy2.12285, PubMed 25713325 -
Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure
Nat Commun, 6, 7229
DOI 10.1038/ncomms8229, PubMed 26068603 -
Surgical anatomy of the superior orbit on ultra-high-resolution MRI at 9.4 Tesla
J Plast Surg Hand Surg, 49 (5), 284-288
DOI 10.3109/2000656X.2015.1041969, PubMed 25946966 -
Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure
Am J Physiol Heart Circ Physiol, 309 (3), H434-49
DOI 10.1152/ajpheart.00253.2014, PubMed 26055793 -
Calcium-activated potassium current: parallels in cardiac development and disease
Acta Physiol (Oxf), 216 (1), 7-9
DOI 10.1111/apha.12556, PubMed 26189640 -
Calcium signalling in developing cardiomyocytes: implications for model systems and disease
J Physiol, 593 (5), 1047-63
DOI 10.1113/jphysiol.2014.274712, PubMed 25641733 -
Effects on serum fractalkine by diet and omega-3 fatty acid intervention: relation to clinical outcome
Mediators Inflamm, 2015, 373070
DOI 10.1155/2015/373070, PubMed 25733777 -
Impact of sex on the prognostic value of high-sensitivity cardiac troponin I in the general population: the HUNT study
Clin Chem, 61 (4), 646-56
DOI 10.1373/clinchem.2014.234369, PubMed 25695851 -
Secretoneurin is a novel prognostic cardiovascular biomarker associated with cardiomyocyte calcium handling
J Am Coll Cardiol, 65 (4), 339-351
DOI 10.1016/j.jacc.2014.10.065, PubMed 25634832 -
Contemporary treatment of amyloid heart disease
Curr Pharm Des, 21 (4), 491-506
DOI 10.2174/138161282104141204143657, PubMed 25483951 -
Reduced expression of aquaporins in human intestinal mucosa in early stage inflammatory bowel disease
Clin Exp Gastroenterol, 8, 49-67
DOI 10.2147/CEG.S70119, PubMed 25624769 -
Targeting cardiomyocyte Ca2+ homeostasis in heart failure
Curr Pharm Des, 21 (4), 431-48
DOI 10.2174/138161282104141204124129, PubMed 25483944 -
Syndecan-4 Regulates Muscle Differentiation and Is Internalized from the Plasma Membrane during Myogenesis
PLoS One, 10 (6), e0129288
DOI 10.1371/journal.pone.0129288, PubMed 26068620 -
Influence of glycosylation on diagnostic and prognostic accuracy of N-terminal pro-B-type natriuretic peptide in acute dyspnea: data from the Akershus Cardiac Examination 2 Study
Clin Chem, 61 (8), 1087-97
DOI 10.1373/clinchem.2015.239673, PubMed 26056354 -
Analysis of AKAP7γ Dimerization
J Signal Transduct, 2015, 371626
DOI 10.1155/2015/371626, PubMed 26417456 -
Lack of collagen VIII reduces fibrosis and promotes early mortality and cardiac dilatation in pressure overload in mice
Cardiovasc Res, 106 (1), 32-42
DOI 10.1093/cvr/cvv041, PubMed 25694587 -
Incidence of Newborn Stabilization and Resuscitation Measures and Guideline Compliance during the First Minutes of Life in Norway
Neonatology, 108 (2), 100-7
DOI 10.1159/000431075, PubMed 26089106 -
Enzymatic detection and quantification assay of isatin, a putative stress biomarker in blood
ACS Chem Neurosci, 6 (8), 1353-60
DOI 10.1021/cn500346x, PubMed 25891478 -
Shedding of syndecan-4 promotes immune cell recruitment and mitigates cardiac dysfunction after lipopolysaccharide challenge in mice
J Mol Cell Cardiol, 88, 133-44
DOI 10.1016/j.yjmcc.2015.10.003, PubMed 26449522 -
Post-Resuscitation ECG for Selection of Patients for Immediate Coronary Angiography in Out-of-Hospital Cardiac Arrest
Circ Cardiovasc Interv, 8 (10)
DOI 10.1161/CIRCINTERVENTIONS.115.002784, PubMed 26453688 -
Syndecan-3 and TFPI colocalize on the surface of endothelial-, smooth muscle-, and cancer cells
PLoS One, 10 (1), e0117404
DOI 10.1371/journal.pone.0117404, PubMed 25617766 -
Enhanced liver fibrosis score predicts transplant-free survival in primary sclerosing cholangitis
Hepatology, 62 (1), 188-97
DOI 10.1002/hep.27825, PubMed 25833813 -
Cardiac Hypertrophy Is Inhibited by a Local Pool of cAMP Regulated by Phosphodiesterase 2
Circ Res, 117 (8), 707-19
DOI 10.1161/CIRCRESAHA.114.305892, PubMed 26243800
Publications 2014
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Hypokalaemia induces Ca²⁺ overload and Ca²⁺ waves in ventricular myocytes by reducing Na⁺,K⁺-ATPase α₂ activity
J Physiol, 593 (6), 1509-21
DOI 10.1113/jphysiol.2014.279893, PubMed 25772299 -
The cardiokine secreted Frizzled-related protein 3, a modulator of Wnt signalling, in clinical and experimental heart failure
J Intern Med, 275 (6), 621-30
DOI 10.1111/joim.12175, PubMed 24330105 -
β-blockade abolishes the augmented cardiac tPA release induced by transactivation of heterodimerised bradykinin receptor-2 and β2-adrenergic receptor in vivo
Thromb Haemost, 112 (5), 951-9
DOI 10.1160/TH14-01-0059, PubMed 25078038 -
Filtering Chest Compression Artifacts Improves the Performance of VF-detection Parameters
COMPUT CARDIOL CONF, 41, 1109-1112 -
The molecular basis of emerin-emerin and emerin-BAF interactions
J Cell Sci, 127 (Pt 18), 3956-69
DOI 10.1242/jcs.148247, PubMed 25052089 -
A proton wire and water channel revealed in the crystal structure of isatin hydrolase
J Biol Chem, 289 (31), 21351-9
DOI 10.1074/jbc.M114.568824, PubMed 24917679 -
Impaired left ventricular mechanical and energetic function in mice after cardiomyocyte-specific excision of Serca2
Am J Physiol Heart Circ Physiol, 306 (7), H1018-24
DOI 10.1152/ajpheart.00741.2013, PubMed 24486508 -
Attenuated development of cardiac fibrosis in left ventricular pressure overload by SM16, an orally active inhibitor of ALK5
J Mol Cell Cardiol, 76, 148-57
DOI 10.1016/j.yjmcc.2014.08.008, PubMed 25169971 -
The homeostatic chemokine CCL21 predicts mortality in aortic stenosis patients and modulates left ventricular remodeling
PLoS One, 9 (11), e112172
DOI 10.1371/journal.pone.0112172, PubMed 25398010 -
Variable t-tubule organization and Ca2+ homeostasis across the atria
Am J Physiol Heart Circ Physiol, 307 (4), H609-20
DOI 10.1152/ajpheart.00295.2014, PubMed 24951751 -
The influence of autologous bone marrow stem cell transplantation on matrix metalloproteinases in patients treated for acute ST-elevation myocardial infarction
Mediators Inflamm, 2014, 385901
DOI 10.1155/2014/385901, PubMed 25294955 -
Comparison of Medical Priority Dispatch (MPD) and Criteria Based Dispatch (CBD) relating to cardiac arrest calls
Resuscitation, 85 (5), 612-6
DOI 10.1016/j.resuscitation.2014.01.029, PubMed 24525117 -
IL-18 neutralization during alveolar hypoxia improves left ventricular diastolic function in mice
Acta Physiol (Oxf), 213 (2), 492-504
DOI 10.1111/apha.12376, PubMed 25182570 -
Loss of lysosomal membrane protein NCU-G1 in mice results in spontaneous liver fibrosis with accumulation of lipofuscin and iron in Kupffer cells
Dis Model Mech, 7 (3), 351-62
DOI 10.1242/dmm.014050, PubMed 24487409 -
Downregulation of L-type Ca2+ channel in rat mesenteric arteries leads to loss of smooth muscle contractile phenotype and inward hypertrophic remodeling
Am J Physiol Heart Circ Physiol, 306 (9), H1287-301
DOI 10.1152/ajpheart.00503.2013, PubMed 24561864 -
Computational modeling of Takotsubo cardiomyopathy: effect of spatially varying β-adrenergic stimulation in the rat left ventricle
Am J Physiol Heart Circ Physiol, 307 (10), H1487-96
DOI 10.1152/ajpheart.00443.2014, PubMed 25239804 -
Reduced visfatin levels in aortic stenosis increase after aortic valve replacement and may contribute to reverse left ventricular remodelling
J Cardiovasc Surg (Torino), 56 (3), 483-92
PubMed 24429804 -
Effects of individualized exercise training in patients with catecholaminergic polymorphic ventricular tachycardia type 1
Am J Cardiol, 113 (11), 1829-33
DOI 10.1016/j.amjcard.2014.03.012, PubMed 24837260 -
M-atrial natriuretic peptide and nitroglycerin in a canine model of experimental acute hypertensive heart failure: differential actions of 2 cGMP activating therapeutics
J Am Heart Assoc, 3 (1), e000206
DOI 10.1161/JAHA.113.000206, PubMed 24385449 -
Non-classical regulation of β1- and β 2-adrenoceptor-mediated inotropic responses in rat heart ventricle by the G protein Gi
Naunyn Schmiedebergs Arch Pharmacol, 387 (12), 1177-86
DOI 10.1007/s00210-014-1036-7, PubMed 25216690 -
A dominant STIM1 mutation causes Stormorken syndrome
Hum Mutat, 35 (5), 556-64
DOI 10.1002/humu.22544, PubMed 24619930 -
Different compartmentation of responses to brain natriuretic peptide and C-type natriuretic peptide in failing rat ventricle
J Pharmacol Exp Ther, 350 (3), 681-90
DOI 10.1124/jpet.114.214882, PubMed 25022512 -
Differential regulation of C-type natriuretic peptide-induced cGMP and functional responses by PDE2 and PDE3 in failing myocardium
Naunyn Schmiedebergs Arch Pharmacol, 387 (5), 407-17
DOI 10.1007/s00210-013-0953-1, PubMed 24424715 -
Apples to apples or apples to oranges? International variation in reporting of process and outcome of care for out-of-hospital cardiac arrest
Resuscitation, 85 (11), 1599-609
DOI 10.1016/j.resuscitation.2014.06.031, PubMed 25010784 -
A computational pipeline for quantification of mouse myocardial stiffness parameters
Comput Biol Med, 53, 65-75
DOI 10.1016/j.compbiomed.2014.07.013, PubMed 25129018 -
Identifying pathogenic processes by integrating microarray data with prior knowledge
BMC Bioinformatics, 15, 115
DOI 10.1186/1471-2105-15-115, PubMed 24758699 -
NEAREST-MANIFOLD CLASSIFICATION APPROACH FOR CARDIAC ARREST RHYTHM INTERPRETATION DURING RESUSCITATION
INT CONF ACOUST SPEE -
Prognostic value of circulating microRNA-210 levels in patients with moderate to severe aortic stenosis
PLoS One, 9 (3), e91812
DOI 10.1371/journal.pone.0091812, PubMed 24626394 -
RFamide Peptides in Early Vertebrate Development
Front Endocrinol (Lausanne), 5, 203
DOI 10.3389/fendo.2014.00203, PubMed 25538682 -
Increased levels of eotaxin and MCP-1 in juvenile dermatomyositis median 16.8 years after disease onset; associations with disease activity, duration and organ damage
PLoS One, 9 (3), e92171
DOI 10.1371/journal.pone.0092171, PubMed 24647150 -
Disease activity and prognostic factors in juvenile dermatomyositis: a long-term follow-up study applying the Paediatric Rheumatology International Trials Organization criteria for inactive disease and the myositis disease activity assessment tool
Rheumatology (Oxford), 53 (9), 1578-85
DOI 10.1093/rheumatology/keu146, PubMed 24692575 -
In active juvenile dermatomyositis, elevated eotaxin and MCP-1 and cholesterol levels in the upper normal range are associated with cardiac dysfunction
Rheumatology (Oxford), 53 (12), 2214-22
DOI 10.1093/rheumatology/keu256, PubMed 24996906 -
Bradycardia during therapeutic hypothermia is associated with good neurologic outcome in comatose survivors of out-of-hospital cardiac arrest
Crit Care Med, 42 (11), 2401-8
DOI 10.1097/CCM.0000000000000515, PubMed 25072762 -
Towards cardiopulmonary resuscitation without vasoactive drugs
Curr Opin Crit Care, 20 (3), 234-41
DOI 10.1097/MCC.0000000000000082, PubMed 24739267 -
Pentosan polysulfate decreases myocardial expression of the extracellular matrix enzyme ADAMTS4 and improves cardiac function in vivo in rats subjected to pressure overload by aortic banding
PLoS One, 9 (3), e89621
DOI 10.1371/journal.pone.0089621, PubMed 24595230 -
Molecular basis of calpain cleavage and inactivation of the sodium-calcium exchanger 1 in heart failure
J Biol Chem, 289 (49), 33984-98
DOI 10.1074/jbc.M114.602581, PubMed 25336645 -
In memory of Guro Valen (1960-2014)
J Mol Cell Cardiol, 79, 254-5
DOI 10.1016/j.yjmcc.2014.11.026, PubMed 25490150
Publications 2013
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Cardiac sodium transport and excitation-contraction coupling
J Mol Cell Cardiol, 61, 11-9
DOI 10.1016/j.yjmcc.2013.06.003, PubMed 23774049 -
A New Algorithm to Diagnose during Chest Compressions: Effect on Cardiopulmonary Resuscitation Delivery
COMPUT CARDIOL CONF, 40, 129-132 -
Time delays and capability of elderly to activate speaker function for continuous telephone CPR
Scand J Trauma Resusc Emerg Med, 21, 40
DOI 10.1186/1757-7241-21-40, PubMed 23676015 -
New pre-arrival instructions can avoid abdominal hand placement for chest compressions
Scand J Trauma Resusc Emerg Med, 21, 47
DOI 10.1186/1757-7241-21-47, PubMed 23799963 -
Quality of CPR performed by trained bystanders with optimized pre-arrival instructions
Resuscitation, 85 (1), 124-30
DOI 10.1016/j.resuscitation.2013.09.015, PubMed 24096105 -
The N-terminal cytoplasmic region of NCBE displays features of an intrinsic disordered structure and represents a novel target for specific drug screening
Front Physiol, 4, 320
DOI 10.3389/fphys.2013.00320, PubMed 24223558 -
Lumican is increased in experimental and clinical heart failure, and its production by cardiac fibroblasts is induced by mechanical and proinflammatory stimuli
FEBS J, 280 (10), 2382-98
DOI 10.1111/febs.12235, PubMed 23480731 -
Decorin, lumican, and their GAG chain-synthesizing enzymes are regulated in myocardial remodeling and reverse remodeling in the mouse
J Appl Physiol (1985), 114 (8), 988-97
DOI 10.1152/japplphysiol.00793.2012, PubMed 23412898 -
Novel insight into the detailed myocardial motion and deformation of the rodent heart using high-resolution phase contrast cardiovascular magnetic resonance
J Cardiovasc Magn Reson, 15 (1), 82
DOI 10.1186/1532-429X-15-82, PubMed 24034168 -
Unwrapping eddy current compensation: improved compensation of eddy current induced baseline shifts in high-resolution phase-contrast MRI at 9.4 Tesla
Magn Reson Med, 72 (4), 1096-102
DOI 10.1002/mrm.25023, PubMed 24264935 -
A Simple Impedance-Based Method for Ventilation Detection During Cardiopulmonary Resuscitation
COMPUT CARDIOL CONF, 40, 807-810 -
Prominent heart organ-level performance deficits in a genetic model of targeted severe and progressive SERCA2 deficiency
PLoS One, 8 (11), e79609
DOI 10.1371/journal.pone.0079609, PubMed 24223976 -
Long-term levosimendan treatment improves systolic function and myocardial relaxation in mice with cardiomyocyte-specific disruption of the Serca2 gene
J Appl Physiol (1985), 115 (10), 1572-80
DOI 10.1152/japplphysiol.01044.2012, PubMed 24072410 -
Multiple causes of fatigue during shortening contractions in rat slow twitch skeletal muscle
PLoS One, 8 (8), e71700
DOI 10.1371/journal.pone.0071700, PubMed 23977116 -
Endothelial permeability in vitro and in vivo: protective actions of ANP and omapatrilat in experimental atherosclerosis
Peptides, 48, 21-6
DOI 10.1016/j.peptides.2013.07.020, PubMed 23927843 -
Contrasting food web factor and body size relationships with Hg and Se concentrations in marine biota
PLoS One, 8 (9), e74695
DOI 10.1371/journal.pone.0074695, PubMed 24019976 -
Beta-adrenergic stimulation maintains cardiac function in Serca2 knockout mice
Biophys J, 104 (6), 1349-56
DOI 10.1016/j.bpj.2013.01.042, PubMed 23528094 -
Integrating multi-scale data to create a virtual physiological mouse heart
Interface Focus, 3 (2), 20120076
DOI 10.1098/rsfs.2012.0076, PubMed 24427525 -
Slow Ca²⁺ sparks de-synchronize Ca²⁺ release in failing cardiomyocytes: evidence for altered configuration of Ca²⁺ release units?
J Mol Cell Cardiol, 58, 41-52
DOI 10.1016/j.yjmcc.2013.01.014, PubMed 23376034 -
Mind the store: modulating Ca(2+) reuptake with a leaky sarcoplasmic reticulum
Cardiovasc Res, 98 (2), 165-8
DOI 10.1093/cvr/cvt069, PubMed 23524302 -
SERCA2 activity is involved in the CNP-mediated functional responses in failing rat myocardium
Br J Pharmacol, 170 (2), 366-79
DOI 10.1111/bph.12282, PubMed 23808942 -
CPR performance - failure proved?
J Emerg Med, 44 (5), 990-1
DOI 10.1016/j.jemermed.2011.07.043, PubMed 23473822 -
Effects of adrenaline on rhythm transitions in out-of-hospital cardiac arrest
Acta Anaesthesiol Scand, 57 (10), 1260-7
DOI 10.1111/aas.12184, PubMed 24032427 -
Clinical pilot study of different hand positions during manual chest compressions monitored with capnography
Resuscitation, 84 (9), 1203-7
DOI 10.1016/j.resuscitation.2013.03.010, PubMed 23499897 -
Probabilistic Classification Approaches for Cardiac Arrest Rhythm Interpretation during Resuscitation
COMPUT CARDIOL CONF, 40, 125-128 -
Reliable extraction of the circulation component in the thoracic impedance measured by defibrillation pads
Resuscitation, 84 (10), 1345-52
DOI 10.1016/j.resuscitation.2013.05.020, PubMed 23747932 -
Feasibility of automated rhythm assessment in chest compression pauses during cardiopulmonary resuscitation
Resuscitation, 84 (9), 1223-8
DOI 10.1016/j.resuscitation.2013.01.034, PubMed 23402965 -
Effect of short- and long-term physical activities on circulating granin protein levels
Regul Pept, 185, 14-9
DOI 10.1016/j.regpep.2013.06.003, PubMed 23816467 -
The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury
Cardiovasc Res, 99 (1), 164-74
DOI 10.1093/cvr/cvt091, PubMed 23580606 -
In juvenile dermatomyositis, cardiac systolic dysfunction is present after long-term follow-up and is predicted by sustained early skin activity
Ann Rheum Dis, 73 (10), 1805-10
DOI 10.1136/annrheumdis-2013-203279, PubMed 23881732 -
Normal training response in skeletal muscle of post-infarction heart failure patients
Eur. J. Sport Sci., 13 (2), 231-239
DOI 10.1080/17461391.2011.624197 -
Deletion of mouse Alkbh7 leads to obesity
J Mol Cell Biol, 5 (3), 194-203
DOI 10.1093/jmcb/mjt012, PubMed 23572141 -
I(CaL) inhibition prevents arrhythmogenic Ca(2+) waves caused by abnormal Ca(2+) sensitivity of RyR or SR Ca(2+) accumulation
Cardiovasc Res, 98 (2), 315-25
DOI 10.1093/cvr/cvt037, PubMed 23417043 -
Innate immune signaling induces expression and shedding of the heparan sulfate proteoglycan syndecan-4 in cardiac fibroblasts and myocytes, affecting inflammation in the pressure-overloaded heart
FEBS J, 280 (10), 2228-47
DOI 10.1111/febs.12161, PubMed 23374111 -
Lack of pro-inflammatory cytokine mobilization predicts poor prognosis in patients with acute heart failure
Cytokine, 61 (3), 962-9
DOI 10.1016/j.cyto.2013.01.006, PubMed 23415671 -
Structural basis and SAR for G007-LK, a lead stage 1,2,4-triazole based specific tankyrase 1/2 inhibitor
J Med Chem, 56 (7), 3012-23
DOI 10.1021/jm4000566, PubMed 23473363 -
Synchrony of cardiomyocyte Ca(2+) release is controlled by T-tubule organization, SR Ca(2+) content, and ryanodine receptor Ca(2+) sensitivity
Biophys J, 104 (8), 1685-97
DOI 10.1016/j.bpj.2013.03.022, PubMed 23601316
Publications 2012
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Different cardiac tissue plasminogen activator release patterns by local stimulation of the endothelium and sympathetic nerves in pigs
Blood Coagul Fibrinolysis, 23 (8), 714-22
DOI 10.1097/MBC.0b013e328357d388, PubMed 22964765 -
The cardiac ventricular 5-HT4 receptor is functional in late foetal development and is reactivated in heart failure
PLoS One, 7 (9), e45489
DOI 10.1371/journal.pone.0045489, PubMed 23029047 -
Sustained blood pressure-lowering actions of subcutaneous B-type natriuretic peptide (nesiritide) in a patient with uncontrolled hypertension
Mayo Clin Proc, 87 (4), 413-5
DOI 10.1016/j.mayocp.2012.02.003, PubMed 22469356 -
IL-18 and IL-12 synergy induces matrix degrading enzymes in the lung
Exp Lung Res, 38 (8), 406-19
DOI 10.3109/01902148.2012.716903, PubMed 22908875 -
Novel protein therapeutics for systolic heart failure: chronic subcutaneous B-type natriuretic peptide
J Am Coll Cardiol, 60 (22), 2305-12
DOI 10.1016/j.jacc.2012.07.056, PubMed 23122795 -
Mutual antagonism between IP(3)RII and miRNA-133a regulates calcium signals and cardiac hypertrophy
J Cell Biol, 199 (5), 783-98
DOI 10.1083/jcb.201111095, PubMed 23166348 -
ROS-mediated decline in maximum Ca2+-activated force in rat skeletal muscle fibers following in vitro and in vivo stimulation
PLoS One, 7 (5), e35226
DOI 10.1371/journal.pone.0035226, PubMed 22629297 -
Circulating cytokine concentrations are not associated with major depressive disorder in a community-based cohort
Gen Hosp Psychiatry, 34 (3), 262-7
DOI 10.1016/j.genhosppsych.2012.01.017, PubMed 22401706 -
Improved MR phase-contrast velocimetry using a novel nine-point balanced motion-encoding scheme with increased robustness to eddy current effects
Magn Reson Med, 69 (1), 48-61
DOI 10.1002/mrm.24226, PubMed 22392844 -
Purification, crystallization and preliminary crystallographic studies of a PacL homologue from Listeria monocytogenes
Acta Crystallogr Sect F Struct Biol Cryst Commun, 68 (Pt 4), 424-7
DOI 10.1107/S1744309112004046, PubMed 22505411 -
Syndecan-4 signaling via NFAT regulates extracellular matrix production and cardiac myofibroblast differentiation in response to mechanical stress
J Mol Cell Cardiol, 54, 73-81
DOI 10.1016/j.yjmcc.2012.11.006, PubMed 23178899 -
Dephosphorylation of cardiac proteins in vitro - a matter of phosphatase specificity
Proteomics, 12 (7), 973-8
DOI 10.1002/pmic.201100116, PubMed 22522803 -
The functional activity of inhibitory G protein (G(i)) is not increased in failing heart ventricle
J Mol Cell Cardiol, 56, 129-38
DOI 10.1016/j.yjmcc.2012.11.015, PubMed 23220156 -
An analysis of deformation-dependent electromechanical coupling in the mouse heart
J Physiol, 590 (18), 4553-69
DOI 10.1113/jphysiol.2012.231928, PubMed 22615436 -
Sodium accumulation in SERCA knockout-induced heart failure
Biophys J, 102 (9), 2039-48
DOI 10.1016/j.bpj.2012.03.045, PubMed 22824267 -
No rest for the weary: diastolic calcium homeostasis in the normal and failing myocardium
Physiology (Bethesda), 27 (5), 308-23
DOI 10.1152/physiol.00021.2012, PubMed 23026754 -
Phospholamban ablation in hearts expressing the high affinity SERCA2b isoform normalizes global Ca²⁺ homeostasis but not Ca²⁺-dependent hypertrophic signaling
Am J Physiol Heart Circ Physiol, 302 (12), H2574-82
DOI 10.1152/ajpheart.01166.2011, PubMed 22505640 -
Human hypertension is characterized by a lack of activation of the antihypertensive cardiac hormones ANP and BNP
J Am Coll Cardiol, 60 (16), 1558-65
DOI 10.1016/j.jacc.2012.05.049, PubMed 23058313 -
Endothelin-1 in the human myocardium and circulating plasma: evaluation before, during and after correction of aortic stenosis with aortic valve replacement
Cardiology, 123 (1), 1-10
DOI 10.1159/000339756, PubMed 22907118 -
GDF-15 is increased during early reperfusion following aortic valve replacement
Scand Cardiovasc J, 46 (2), 99-106
DOI 10.3109/14017431.2011.649489, PubMed 22168128 -
Hepatocyte growth factor and cardiomyopathy in dialysis patients
Hypertension, 60 (3), e24; author reply e25-6
DOI 10.1161/HYPERTENSIONAHA.112.198424, PubMed 22868387 -
Neutral endopeptidase inhibition and the natriuretic peptide system: an evolving strategy in cardiovascular therapeutics
Eur Heart J, 34 (12), 886-893c
DOI 10.1093/eurheartj/ehs262, PubMed 22942338 -
Hyperoxia during early reperfusion does not increase ischemia/reperfusion injury
Eur J Cardiothorac Surg, 41 (1), 149-53
DOI 10.1016/j.ejcts.2011.04.022, PubMed 21636285 -
Can drugs ever improve outcome after cardiac arrest?
Resuscitation, 83 (6), 663-4
DOI 10.1016/j.resuscitation.2012.03.007, PubMed 22429971 -
Intrinsic skeletal muscle alterations in chronic heart failure patients: a disease-specific myopathy or a result of deconditioning?
Heart Fail Rev, 17 (3), 421-36
DOI 10.1007/s10741-011-9289-4, PubMed 21996779 -
Prognostic value of chromogranin A in severe sepsis: data from the FINNSEPSIS study
Intensive Care Med, 38 (5), 820-9
DOI 10.1007/s00134-012-2546-8, PubMed 22491939 -
Secretogranin II; a protein increased in the myocardium and circulation in heart failure with cardioprotective properties
PLoS One, 7 (5), e37401
DOI 10.1371/journal.pone.0037401, PubMed 22655045 -
Diagnostic utility of a single-epitope sandwich B-type natriuretic peptide assay in stable coronary artery disease: data from the Akershus Cardiac Examination (ACE) 1 Study
Clin Biochem, 45 (16-17), 1269-75
DOI 10.1016/j.clinbiochem.2012.05.010, PubMed 22609895 -
Cardiac troponin T levels and exercise stress testing in patients with suspected coronary artery disease: the Akershus Cardiac Examination (ACE) 1 study
Clin Sci (Lond), 122 (12), 599-606
DOI 10.1042/CS20110557, PubMed 22239123 -
HIV as a risk factor for cardiac disease in Botswana: a cross-sectional study
Int Health, 4 (1), 30-7
DOI 10.1016/j.inhe.2011.12.003, PubMed 24030878 -
Differential regulation of extracellular matrix constituents in myocardial remodeling with and without heart failure following pressure overload
Matrix Biol, 32 (2), 133-42
DOI 10.1016/j.matbio.2012.11.011, PubMed 23220517 -
From global to local: a new understanding of cardiac electromechanical coupling
Tidsskr Nor Laegeforen, 132 (12-13), 1457-60
DOI 10.4045/tidsskr.11.1353, PubMed 22766818 -
Calcium release units in heart failure: that's about the size of it
Cardiovasc Res, 95 (4), 397-8
DOI 10.1093/cvr/cvs241, PubMed 22832099 -
Extreme sarcoplasmic reticulum volume loss and compensatory T-tubule remodeling after Serca2 knockout
Proc Natl Acad Sci U S A, 109 (10), 3997-4001
DOI 10.1073/pnas.1120172109, PubMed 22355118 -
Special Interest Group on Cardiac Physiology established within the Scandinavian Physiological Society
Acta Physiol (Oxf), 204 (4), 464
DOI 10.1111/j.1748-1716.2011.02374.x, PubMed 22364639 -
Macrophage inflammatory protein-1β: a novel prognostic biomarker in atherosclerosis?
Cardiology, 121 (3), 149-51
DOI 10.1159/000336484, PubMed 22441313 -
Chemokines regulate small leucine-rich proteoglycans in the extracellular matrix of the pressure-overloaded right ventricle
J Appl Physiol (1985), 112 (8), 1372-82
DOI 10.1152/japplphysiol.01350.2011, PubMed 22345433 -
The homeostatic chemokine CCL21 predicts mortality and may play a pathogenic role in heart failure
PLoS One, 7 (3), e33038
DOI 10.1371/journal.pone.0033038, PubMed 22427939 -
ACE inhibition prevents diastolic Ca2+ overload and loss of myofilament Ca2+ sensitivity after myocardial infarction
Curr Mol Med, 12 (2), 206-17
DOI 10.2174/156652412798889045, PubMed 22280358
Publications 2011
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Agents increasing cyclic GMP amplify 5-HT4-elicited positive inotropic response in failing rat cardiac ventricle
Naunyn Schmiedebergs Arch Pharmacol, 384 (6), 543-53
DOI 10.1007/s00210-011-0670-6, PubMed 21901315 -
Divide and conquer: the application of organelle proteomics to heart failure
Circ Res, 108 (4), 512-26
DOI 10.1161/CIRCRESAHA.110.226910, PubMed 21335433 -
Suppression of the cardiopulmonary resuscitation artefacts using the instantaneous chest compression rate extracted from the thoracic impedance
Resuscitation, 83 (6), 692-8
DOI 10.1016/j.resuscitation.2011.11.029, PubMed 22198092 -
Video analysis of dispatcher-rescuer teamwork-Effects on CPR technique and performance
Resuscitation, 83 (4), 494-9
DOI 10.1016/j.resuscitation.2011.09.021, PubMed 21982923 -
Inhibition of SMAD2 phosphorylation preserves cardiac function during pressure overload
Cardiovasc Res, 93 (1), 100-10
DOI 10.1093/cvr/cvr294, PubMed 22049534 -
A mouse model of reverse cardiac remodelling following banding-debanding of the ascending aorta
Acta Physiol (Oxf), 205 (1), 92-102
DOI 10.1111/j.1748-1716.2011.02369.x, PubMed 21974781 -
P-type ATPases at a glance
J Cell Sci, 124 (Pt 15), 2515-9
DOI 10.1242/jcs.088716, PubMed 21768325 -
A genetic variant of the atrial natriuretic peptide gene is associated with cardiometabolic protection in the general community
J Am Coll Cardiol, 58 (6), 629-36
DOI 10.1016/j.jacc.2011.05.011, PubMed 21798427 -
Effects of serum-free storage on morphology, phenotype, and viability of ex vivo cultured human conjunctival epithelium
Exp Eye Res, 94 (1), 109-16
DOI 10.1016/j.exer.2011.11.015, PubMed 22154551 -
Syndecan-4 is essential for development of concentric myocardial hypertrophy via stretch-induced activation of the calcineurin-NFAT pathway
PLoS One, 6 (12), e28302
DOI 10.1371/journal.pone.0028302, PubMed 22164265 -
Circulating CD34⁺ progenitor cells and growth factors in patients treated with PCI for acute myocardial infarction or stable angina pectoris
Scand J Clin Lab Invest, 71 (4), 322-9
DOI 10.3109/00365513.2011.565367, PubMed 21463159 -
Cyclic AMP-dependent inotropic effects are differentially regulated by muscarinic G(i)-dependent constitutive inhibition of adenylyl cyclase in failing rat ventricle
Br J Pharmacol, 162 (4), 908-16
DOI 10.1111/j.1476-5381.2010.01097.x, PubMed 21039419 -
Cortisol response to stress is associated with myocardial remodeling in salmonid fishes
J Exp Biol, 214 (Pt 8), 1313-21
DOI 10.1242/jeb.053058, PubMed 21430209 -
Cardiopulmonary resuscitation or shock first--no answers yet?
Prehosp Emerg Care, 15 (4), 577-8; author reply 579-80
DOI 10.3109/10903127.2011.608873, PubMed 21870948 -
Lack of CCR7 induces pulmonary hypertension involving perivascular leukocyte infiltration and inflammation
Am J Physiol Lung Cell Mol Physiol, 301 (1), L50-9
DOI 10.1152/ajplung.00048.2010, PubMed 21498626 -
Calcium dynamics in the ventricular myocytes of SERCA2 knockout mice: A modeling study
Biophys J, 100 (2), 322-31
DOI 10.1016/j.bpj.2010.11.048, PubMed 21244828 -
Methods in cardiomyocyte isolation, culture, and gene transfer
J Mol Cell Cardiol, 51 (3), 288-98
DOI 10.1016/j.yjmcc.2011.06.012, PubMed 21723873 -
Hypoxia inducible factor 1 links fast-patterned muscle activity and fast muscle phenotype in rats
J Physiol, 589 (Pt 6), 1443-54
DOI 10.1113/jphysiol.2010.202762, PubMed 21262877 -
Cardiac O-GlcNAc signaling is increased in hypertrophy and heart failure
Physiol Genomics, 44 (2), 162-72
DOI 10.1152/physiolgenomics.00016.2011, PubMed 22128088 -
Angiotensin II and norepinephrine activate specific calcineurin-dependent NFAT transcription factor isoforms in cardiomyocytes
J Appl Physiol (1985), 111 (5), 1278-89
DOI 10.1152/japplphysiol.01383.2010, PubMed 21474694 -
Pro-B-type natriuretic peptide(1-108) circulates in the general community: plasma determinants and detection of left ventricular dysfunction
J Am Coll Cardiol, 57 (12), 1386-95
DOI 10.1016/j.jacc.2011.01.005, PubMed 21414536 -
Experimental mild renal insufficiency mediates early cardiac apoptosis, fibrosis, and diastolic dysfunction: a kidney-heart connection
Am J Physiol Regul Integr Comp Physiol, 302 (2), R292-9
DOI 10.1152/ajpregu.00194.2011, PubMed 22071162 -
Predictive utility of atrial, N-terminal pro-atrial, and N-terminal pro-B-type natriuretic peptides for mortality and cardiovascular events in the general community: a 9-year follow-up study
Mayo Clin Proc, 86 (12), 1154-60
DOI 10.4065/mcp.2011.0437, PubMed 22134933 -
A structural overview of the plasma membrane Na+,K+-ATPase and H+-ATPase ion pumps
Nat Rev Mol Cell Biol, 12 (1), 60-70
DOI 10.1038/nrm3031, PubMed 21179061 -
Attenuated fatigue in slow twitch skeletal muscle during isotonic exercise in rats with chronic heart failure
PLoS One, 6 (7), e22695
DOI 10.1371/journal.pone.0022695, PubMed 21799933 -
A randomized trial on elderly laypersons' CPR performance in a realistic cardiac arrest simulation
Acta Anaesthesiol Scand, 56 (1), 124-31
DOI 10.1111/j.1399-6576.2011.02566.x, PubMed 22092097 -
Prediction of countershock success in patients using the autoregressive spectral estimation
Methods Inf Med, 51 (1), 13-20
DOI 10.3414/ME10-01-0033, PubMed 21643621 -
Outcome when adrenaline (epinephrine) was actually given vs. not given - post hoc analysis of a randomized clinical trial
Resuscitation, 83 (3), 327-32
DOI 10.1016/j.resuscitation.2011.11.011, PubMed 22115931 -
Mechanism of prolonged electromechanical delay in late activated myocardium during left bundle branch block
Am J Physiol Heart Circ Physiol, 301 (6), H2334-43
DOI 10.1152/ajpheart.00644.2011, PubMed 21984549 -
Urinary C-type natriuretic peptide excretion: a potential novel biomarker for renal fibrosis during aging
Am J Physiol Renal Physiol, 301 (5), F943-52
DOI 10.1152/ajprenal.00170.2011, PubMed 21865266 -
Cardiac dysfunction in juvenile dermatomyositis: a case-control study
Ann Rheum Dis, 70 (5), 766-71
DOI 10.1136/ard.2010.137968, PubMed 21216816 -
Calcium controls cardiac function--by all means!
J Physiol, 589 (Pt 12), 2919-20
DOI 10.1113/jphysiol.2011.210989, PubMed 21676882 -
Slowed relaxation and preserved maximal force in soleus muscles of mice with targeted disruption of the Serca2 gene in skeletal muscle
J Physiol, 589 (Pt 24), 6139-55
DOI 10.1113/jphysiol.2011.211987, PubMed 21946846 -
Ca(2+) wave probability is determined by the balance between SERCA2-dependent Ca(2+) reuptake and threshold SR Ca(2+) content
Cardiovasc Res, 90 (3), 503-12
DOI 10.1093/cvr/cvr013, PubMed 21242164 -
Secretion of glycosylated pro-B-type natriuretic peptide from normal cardiomyocytes
Clin Chem, 57 (6), 864-73
DOI 10.1373/clinchem.2010.157438, PubMed 21482747 -
Strong and weak aspects of an established post-resuscitation treatment protocol-A five-year observational study
Resuscitation, 82 (9), 1186-93
DOI 10.1016/j.resuscitation.2011.05.003, PubMed 21636202 -
A comparison of intravascular and surface cooling techniques in comatose cardiac arrest survivors
Crit Care Med, 39 (3), 443-9
DOI 10.1097/CCM.0b013e318206b80f, PubMed 21169821 -
Lack of chemokine signaling through CXCR5 causes increased mortality, ventricular dilatation and deranged matrix during cardiac pressure overload
PLoS One, 6 (4), e18668
DOI 10.1371/journal.pone.0018668, PubMed 21533157 -
Full-length cardiac Na+/Ca2+ exchanger 1 protein is not phosphorylated by protein kinase A
Am J Physiol Cell Physiol, 300 (5), C989-97
DOI 10.1152/ajpcell.00196.2010, PubMed 21289289
Publications 2010
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Collagen isoform shift during the early phase of reverse left ventricular remodelling after relief of pressure overload
Eur Heart J, 32 (2), 236-45
DOI 10.1093/eurheartj/ehq166, PubMed 20525982 -
Reference gene alternatives to Gapdh in rodent and human heart failure gene expression studies
BMC Mol Biol, 11, 22
DOI 10.1186/1471-2199-11-22, PubMed 20331858 -
Renal and anti-aldosterone actions of vasopressin-2 receptor antagonism and B-type natriuretic peptide in experimental heart failure
Circ Heart Fail, 3 (3), 412-9
DOI 10.1161/CIRCHEARTFAILURE.109.916114, PubMed 20176717 -
European Resuscitation Council Guidelines for Resuscitation 2010 Section 4. Adult advanced life support
Notfall Rettungsmed., 13 (7), 559-620
DOI 10.1007/s10049-010-1370-3 -
High-intensity exercise training in mice with cardiomyocyte-specific disruption of Serca2
J Appl Physiol (1985), 108 (5), 1311-20
DOI 10.1152/japplphysiol.01133.2009, PubMed 20167673 -
Exercise training before cardiac-specific Serca2 disruption attenuates the decline in cardiac function in mice
J Appl Physiol (1985), 109 (6), 1749-55
DOI 10.1152/japplphysiol.00282.2010, PubMed 20864565 -
Cell treatment after acute myocardial infarction prevents early decline in circulating IGF-1
Scand Cardiovasc J, 44 (5), 267-72
DOI 10.3109/14017431.2010.490949, PubMed 21080844 -
Cre-loxP DNA recombination is possible with only minimal unspecific transcriptional changes and without cardiomyopathy in Tg(alphaMHC-MerCreMer) mice
Am J Physiol Heart Circ Physiol, 299 (5), H1671-8
DOI 10.1152/ajpheart.01155.2009, PubMed 20802136 -
Postconditioning in mouse hearts is inhibited by blocking the reverse mode of the sodium-calcium exchanger
Interact Cardiovasc Thorac Surg, 10 (5), 743-8
DOI 10.1510/icvts.2009.217083, PubMed 20139199 -
Mechanical chest compressions with trapezoidal waveform improve haemodynamics during cardiac arrest
Resuscitation, 82 (2), 213-8
DOI 10.1016/j.resuscitation.2010.10.009, PubMed 21093141 -
Herpes simplex virus-induced cardiomyopathy successfully treated with acyclovir
Wien Klin Wochenschr, 122 (19-20), 592-5
DOI 10.1007/s00508-010-1456-4, PubMed 20865454 -
Cardiomyocyte-specific disruption of Serca2 in adult mice causes sarco(endo)plasmic reticulum stress and apoptosis
Cell Calcium, 49 (4), 201-7
DOI 10.1016/j.ceca.2010.09.009, PubMed 20965565 -
Control of Ca2+ release by action potential configuration in normal and failing murine cardiomyocytes
Biophys J, 99 (5), 1377-86
DOI 10.1016/j.bpj.2010.06.055, PubMed 20816049 -
There goes the neighborhood: pathological alterations in T-tubule morphology and consequences for cardiomyocyte Ca2+ handling
J Biomed Biotechnol, 2010, 503906
DOI 10.1155/2010/503906, PubMed 20396394 -
Improving outcome after out-of-hospital cardiac arrest by strengthening weak links of the local Chain of Survival; quality of advanced life support and post-resuscitation care
Resuscitation, 81 (4), 422-6
DOI 10.1016/j.resuscitation.2009.12.020, PubMed 20122786 -
Plasma IL-18 and IL-18BP are altered differently in reverse remodeling following aortic valve replacement
Scand Cardiovasc J, 44 (2), 113-8
DOI 10.3109/14017430903426902, PubMed 19961286 -
A novel atrial natriuretic peptide based therapeutic in experimental angiotensin II mediated acute hypertension
Hypertension, 56 (6), 1152-9
DOI 10.1161/HYPERTENSIONAHA.110.159210, PubMed 20975033 -
The prognostic value of N-terminal pro-B-type natriuretic peptide for death and cardiovascular events in healthy normal and stage A/B heart failure subjects
J Am Coll Cardiol, 55 (19), 2140-7
DOI 10.1016/j.jacc.2010.01.031, PubMed 20447539 -
Training effects on skeletal muscle calcium handling in human chronic heart failure
Med Sci Sports Exerc, 42 (5), 847-55
DOI 10.1249/MSS.0b013e3181c29ec1, PubMed 19996998 -
A randomized trial of the capability of elderly lay persons to perform chest compression only CPR versus standard 30:2 CPR
Resuscitation, 81 (7), 887-92
DOI 10.1016/j.resuscitation.2010.03.028, PubMed 20418006 -
Presence of Borrelia burgdorferi in endomyocardial biopsies in patients with new-onset unexplained dilated cardiomyopathy
Med Microbiol Immunol, 199 (2), 139-43
DOI 10.1007/s00430-009-0141-6, PubMed 20052487 -
Chromogranin B in heart failure: a putative cardiac biomarker expressed in the failing myocardium
Circ Heart Fail, 3 (4), 503-11
DOI 10.1161/CIRCHEARTFAILURE.109.867747, PubMed 20519641 -
Pulmonary outcome in juvenile dermatomyositis: a case-control study
Ann Rheum Dis, 70 (1), 86-91
DOI 10.1136/ard.2010.131433, PubMed 20805295 -
Preserved metabolic reserve capacity in skeletal muscle of post-infarction heart failure patients
Scand J Med Sci Sports, 22 (2), 199-206
DOI 10.1111/j.1600-0838.2010.01226.x, PubMed 20874858 -
Functional coupling of alpha(2)-isoform Na(+)/K(+)-ATPase and Ca(2+) extrusion through the Na(+)/Ca(2+)-exchanger in cardiomyocytes
Cell Calcium, 48 (1), 54-60
DOI 10.1016/j.ceca.2010.06.006, PubMed 20667414 -
Discriminating the effect of accelerated compression from accelerated decompression during high-impulse CPR in a porcine model of cardiac arrest
Resuscitation, 81 (4), 488-92
DOI 10.1016/j.resuscitation.2009.12.028, PubMed 20122780 -
Multiple cytokine biomarkers in heart failure
Expert Rev Mol Diagn, 10 (2), 147-57
DOI 10.1586/erm.10.3, PubMed 20214534 -
Circulating cytokine levels in mice with heart failure are etiology dependent
J Appl Physiol (1985), 108 (5), 1357-64
DOI 10.1152/japplphysiol.01084.2009, PubMed 20224000
Publications 2009
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Moderate heart dysfunction in mice with inducible cardiomyocyte-specific excision of the Serca2 gene
J Mol Cell Cardiol, 47 (2), 180-7
DOI 10.1016/j.yjmcc.2009.03.013, PubMed 19328205 -
Mice carrying a conditional Serca2(flox) allele for the generation of Ca(2+) handling-deficient mouse models
Cell Calcium, 46 (3), 219-25
DOI 10.1016/j.ceca.2009.07.004, PubMed 19692123 -
Tamoxifen administration routes and dosage for inducible Cre-mediated gene disruption in mouse hearts
Transgenic Res, 19 (4), 715-25
DOI 10.1007/s11248-009-9342-4, PubMed 19894134 -
Hospital employees improve basic life support skills and confidence with a personal resuscitation manikin and a 24-min video instruction
Resuscitation, 80 (8), 898-902
DOI 10.1016/j.resuscitation.2009.06.009, PubMed 19573973 -
B-type natriuretic peptide 8-32, which is produced from mature BNP 1-32 by the metalloprotease meprin A, has reduced bioactivity
Am J Physiol Regul Integr Comp Physiol, 296 (6), R1744-50
DOI 10.1152/ajpregu.00059.2009, PubMed 19386989 -
Local renal delivery of a natriuretic peptide a renal-enhancing strategy for B-type natriuretic peptide in overt experimental heart failure
J Am Coll Cardiol, 53 (15), 1302-8
DOI 10.1016/j.jacc.2009.01.030, PubMed 19358945 -
Increased production of CXCL16 in experimental and clinical heart failure: a possible role in extracellular matrix remodeling
Circ Heart Fail, 2 (6), 624-32
DOI 10.1161/CIRCHEARTFAILURE.108.821074, PubMed 19919988 -
Impaired effector memory T-cell regulation facilitates graft versus host disease in CCR7-deficient bone marrow transplant chimeras
Transplantation, 88 (5), 631-9
DOI 10.1097/TP.0b013e3181b241df, PubMed 19741459 -
Development of the probability of return of spontaneous circulation in intervals without chest compressions during out-of-hospital cardiac arrest: an observational study
BMC Med, 7, 6
DOI 10.1186/1741-7015-7-6, PubMed 19200355 -
Treatment of asystole and PEA
Resuscitation, 80 (9), 975-6
DOI 10.1016/j.resuscitation.2009.05.019, PubMed 19581035 -
Activation of muscarinic receptors elicits inotropic responses in ventricular muscle from rats with heart failure through myosin light chain phosphorylation
Br J Pharmacol, 156 (4), 575-86
DOI 10.1111/j.1750-3639.2009.00016.x, PubMed 19159405 -
A least mean-square filter for the estimation of the cardiopulmonary resuscitation artifact based on the frequency of the compressions
IEEE Trans Biomed Eng, 56 (4), 1052-62
DOI 10.1109/TBME.2008.2010329, PubMed 19150778 -
Separate mechanisms cause anemia in ischemic vs. nonischemic murine heart failure
Am J Physiol Regul Integr Comp Physiol, 298 (3), R808-14
DOI 10.1152/ajpregu.00250.2009, PubMed 20032264 -
Effect of piboserod, a 5-HT4 serotonin receptor antagonist, on left ventricular function in patients with symptomatic heart failure
Eur J Heart Fail, 11 (8), 771-8
DOI 10.1093/eurjhf/hfp087, PubMed 19567409 -
Cardiac structural and functional changes in competitive amateur cyclists
Echocardiography, 27 (1), 11-6
DOI 10.1111/j.1540-8175.2009.00965.x, PubMed 19765071 -
Which factors influence spontaneous state transitions during resuscitation?
Resuscitation, 80 (8), 863-9
DOI 10.1016/j.resuscitation.2009.04.042, PubMed 19525053 -
Effects of bilirubin ditaurate overload on canalicular membrane function and ultrastructure of the pig liver
Injury, 40 (8), 868-72
DOI 10.1016/j.injury.2008.11.017, PubMed 19376516 -
High school students as ambassadors of CPR--a model for reaching the most appropriate target population?
Resuscitation, 81 (1), 78-81
DOI 10.1016/j.resuscitation.2009.09.030, PubMed 19913984 -
DYADIC GEOMETRY IN NORMAL AND FAILING CARDIOMYOCYTES
J. Appl. Physiol., 107 (6), 1985 -
Sodium accumulation promotes diastolic dysfunction in end-stage heart failure following Serca2 knockout
J Physiol, 588 (Pt 3), 465-78
DOI 10.1113/jphysiol.2009.183517, PubMed 20008467 -
Cardiac troponin I degradation in serum of patients with hypertrophic obstructive cardiomyopathy undergoing percutaneous septal ablation
Cardiology, 114 (3), 167-73
DOI 10.1159/000226596, PubMed 19571537 -
A human atrial natriuretic peptide gene mutation reveals a novel peptide with enhanced blood pressure-lowering, renal-enhancing, and aldosterone-suppressing actions
J Am Coll Cardiol, 54 (11), 1024-32
DOI 10.1016/j.jacc.2009.04.080, PubMed 19729120 -
Causes of fatigue in slow-twitch rat skeletal muscle during dynamic activity
Am J Physiol Regul Integr Comp Physiol, 297 (3), R900-10
DOI 10.1152/ajpregu.91043.2008, PubMed 19625691 -
Slowing of cardiomyocyte Ca2+ release and contraction during heart failure progression in postinfarction mice
Am J Physiol Heart Circ Physiol, 296 (4), H1069-79
DOI 10.1152/ajpheart.01009.2008, PubMed 19201998 -
Gene expression profiles reflect sclerosing cholangitis activity in abcb4 (-/-) mice
Scand J Gastroenterol, 44 (2), 211-8
DOI 10.1080/00365520802400867, PubMed 18785065 -
Feasibility of MRI in experimentally induced inflammatory small bowel disease: a pilot study in a porcine model
Dig Dis Sci, 55 (1), 14-20
DOI 10.1007/s10620-008-0707-y, PubMed 19301126 -
Comparison of mechanical characteristics of the human and porcine chest during cardiopulmonary resuscitation
Resuscitation, 80 (4), 463-9
DOI 10.1016/j.resuscitation.2008.12.014, PubMed 19195761 -
Outcome, timing and adverse events in therapeutic hypothermia after out-of-hospital cardiac arrest
Acta Anaesthesiol Scand, 53 (7), 926-34
DOI 10.1111/j.1399-6576.2009.02021.x, PubMed 19549271 -
Acute ischemic heart disease alters ventricular fibrillation waveform characteristics in out-of hospital cardiac arrest
Resuscitation, 80 (4), 412-7
DOI 10.1016/j.resuscitation.2009.01.012, PubMed 19217199 -
Out-of hospital advanced life support with or without a physician: effects on quality of CPR and outcome
Resuscitation, 80 (11), 1248-52
DOI 10.1016/j.resuscitation.2009.07.018, PubMed 19709795 -
Intravenous drug administration during out-of-hospital cardiac arrest: a randomized trial
JAMA, 302 (20), 2222-9
DOI 10.1001/jama.2009.1729, PubMed 19934423 -
Effect of implementation of new resuscitation guidelines on quality of cardiopulmonary resuscitation and survival
Resuscitation, 80 (4), 407-11
DOI 10.1016/j.resuscitation.2008.12.005, PubMed 19167148 -
Are we closer to a new strategy in the treatment of cardiac arrest?
Resuscitation, 80 (6), 613-4
DOI 10.1016/j.resuscitation.2009.04.001, PubMed 19410355 -
Temporary fatigue and altered extracellular matrix in skeletal muscle during progression of heart failure in rats
Am J Physiol Regul Integr Comp Physiol, 297 (1), R26-33
DOI 10.1152/ajpregu.90617.2008, PubMed 19339678 -
Commentaries on viewpoint: The cardiac contraction cycle: is Ca2+ going local? Counterpoint
J Appl Physiol (1985), 107 (6), 1985-7; author reply 1988
DOI 10.1152/japplphysiol.01028.2009, PubMed 19952386 -
Cumulative organ damage and prognostic factors in juvenile dermatomyositis: a cross-sectional study median 16.8 years after symptom onset
Rheumatology (Oxford), 48 (12), 1541-7
DOI 10.1093/rheumatology/kep302, PubMed 19776224 -
[Why not health universities?]
Tidsskr Nor Laegeforen, 129 (16), 1620
DOI 10.4045/tidsskr.09.0833, PubMed 19721472 -
Cardiomyocytes from postinfarction failing rat hearts have improved ischemia tolerance
Am J Physiol Heart Circ Physiol, 296 (3), H787-95
DOI 10.1152/ajpheart.00796.2008, PubMed 19136604 -
Soluble e-selectin is an inverse and independent predictor of left ventricular wall thickness in end-stage renal disease patients
Nephron Clin Pract, 114 (1), c74-80
DOI 10.1159/000252806, PubMed 19851079 -
Inadvertent phosphorylation of survival kinases in isolated perfused hearts: a word of caution
Basic Res Cardiol, 104 (4), 412-23
DOI 10.1007/s00395-009-0780-1, PubMed 19198917 -
Reduced SERCA2 abundance decreases the propensity for Ca2+ wave development in ventricular myocytes
Cardiovasc Res, 86 (1), 63-71
DOI 10.1093/cvr/cvp401, PubMed 20019150 -
Studies in hypothermia-treated cardiac arrest patients are needed to establish the accuracy of proposed outcome predictors
Crit Care Med, 37 (8), 2485-6
DOI 10.1097/CCM.0b013e3181ad4e8f, PubMed 19609125 -
Advanced life support performance with manual and mechanical chest compressions in a randomized, multicentre manikin study
Resuscitation, 80 (10), 1152-7
DOI 10.1016/j.resuscitation.2009.07.001, PubMed 19665833 -
Handling of drug-related emergencies: an evaluation of emergency medical dispatch
Eur J Emerg Med, 16 (1), 37-42
DOI 10.1097/MEJ.0b013e3283036e47, PubMed 19106718 -
Involvement of calpains in Ca2+-induced disruption of excitation-contraction coupling in mammalian skeletal muscle fibers
Am J Physiol Cell Physiol, 296 (5), C1115-22
DOI 10.1152/ajpcell.00008.2009, PubMed 19295178 -
Increased systemic and myocardial expression of neutrophil gelatinase-associated lipocalin in clinical and experimental heart failure
Eur Heart J, 30 (10), 1229-36
DOI 10.1093/eurheartj/ehp088, PubMed 19329498 -
Elevated levels of activin A in clinical and experimental pulmonary hypertension
J Appl Physiol (1985), 106 (4), 1356-64
DOI 10.1152/japplphysiol.90719.2008, PubMed 19196915 -
The effect of transport on quality of cardiopulmonary resuscitation in out-of-hospital cardiac arrest
Resuscitation, 80 (8), 843-8
DOI 10.1016/j.resuscitation.2009.03.032, PubMed 19477573
Publications 2008
-
5-HT4-elicited positive inotropic response is mediated by cAMP and regulated by PDE3 in failing rat and human cardiac ventricles
Br J Pharmacol, 155 (7), 1005-14
DOI 10.1038/bjp.2008.339, PubMed 18846035 -
Real-time reconfigurable subthreshold CMOS perceptron
IEEE Trans Neural Netw, 19 (4), 645-57
DOI 10.1109/TNN.2007.912572, PubMed 18390310 -
Alterations in circulating activin A, GDF-15, TGF-beta3 and MMP-2, -3, and -9 during one year of left ventricular reverse remodelling in patients operated for severe aortic stenosis
Eur J Heart Fail, 10 (12), 1201-7
DOI 10.1016/j.ejheart.2008.09.010, PubMed 18996047 -
Quality of chest compressions during 10min of single-rescuer basic life support with different compression: ventilation ratios in a manikin model
Resuscitation, 77 (1), 95-100
DOI 10.1016/j.resuscitation.2007.11.009, PubMed 18207627 -
Effects of hydrogen sulphide on ischaemia-reperfusion injury and ischaemic preconditioning in the isolated, perfused rat heart
Eur J Cardiothorac Surg, 34 (2), 344-9
DOI 10.1016/j.ejcts.2008.03.017, PubMed 18455926 -
Slow contractions characterize failing rat hearts
Basic Res Cardiol, 103 (4), 328-44
DOI 10.1007/s00395-008-0719-y, PubMed 18347833 -
Using within-patient correlation to improve the accuracy of shock outcome prediction for cardiac arrest
Resuscitation, 78 (1), 46-51
DOI 10.1016/j.resuscitation.2008.02.018, PubMed 18485562 -
Chest compression quality variables influencing the temporal development of ROSC-predictors calculated from the ECG during VF
Resuscitation, 80 (2), 177-82
DOI 10.1016/j.resuscitation.2008.09.011, PubMed 19059692 -
Effect of plasma protein depletion on BNP-32 recovery
Clin Chem, 54 (5), 933-4
DOI 10.1373/clinchem.2007.098038, PubMed 18443186 -
Cytokine expression profiling of the myocardium reveals a role for CX3CL1 (fractalkine) in heart failure
J Mol Cell Cardiol, 45 (2), 261-9
DOI 10.1016/j.yjmcc.2008.05.009, PubMed 18585734 -
Preconditioning effects of steroids and hyperoxia on cardiac ischemia-reperfusion injury and vascular reactivity
Eur J Cardiothorac Surg, 33 (3), 355-63
DOI 10.1016/j.ejcts.2007.12.017, PubMed 18221880 -
Diastolic dysfunction in alveolar hypoxia: a role for interleukin-18-mediated increase in protein phosphatase 2A
Cardiovasc Res, 80 (1), 47-54
DOI 10.1093/cvr/cvn180, PubMed 18599478 -
Impact of a self-instruction CPR kit on 7th graders' and adults' skills and CPR performance
Resuscitation, 79 (1), 103-8
DOI 10.1016/j.resuscitation.2008.04.030, PubMed 18656297 -
Anterior myocardial infarction with acute percutaneous coronary intervention and intracoronary injection of autologous mononuclear bone marrow cells: safety, clinical outcome, and serial changes in left ventricular function during 12-months' follow-up
J Am Coll Cardiol, 51 (6), 674-6
DOI 10.1016/j.jacc.2007.10.032, PubMed 18261689 -
Targeting the kidney in acute decompensated heart failure: conventional diuretics and renal-acting vasodilators
Rev Cardiovasc Med, 9 (1), 39-45
PubMed 18418308 -
B-type natriuretic peptide: beyond a diagnostic
Heart Fail Clin, 4 (4), 449-54
DOI 10.1016/j.hfc.2008.03.011, PubMed 18760756 -
ABCB4 sequence variations in young adults with cholesterol gallstone disease
Liver Int, 29 (5), 743-7
DOI 10.1111/j.1478-3231.2008.01914.x, PubMed 19018976 -
Post-cardiac arrest syndrome: epidemiology, pathophysiology, treatment, and prognostication. A consensus statement from the International Liaison Committee on Resuscitation (American Heart Association, Australian and New Zealand Council on Resuscitation, European Resuscitation Council, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Council of Asia, and the Resuscitation Council of Southern Africa); the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; and the Stroke Council
Circulation, 118 (23), 2452-83
DOI 10.1161/CIRCULATIONAHA.108.190652, PubMed 18948368 -
Improving countershock success prediction during cardiopulmonary resuscitation using ventricular fibrillation features from higher ECG frequency bands
Resuscitation, 79 (3), 453-9
DOI 10.1016/j.resuscitation.2008.07.024, PubMed 18954929 -
Post-cardiac arrest syndrome: epidemiology, pathophysiology, treatment, and prognostication. A Scientific Statement from the International Liaison Committee on Resuscitation; the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; the Council on Stroke
Resuscitation, 79 (3), 350-79
DOI 10.1016/j.resuscitation.2008.09.017, PubMed 18963350 -
Time used for ventilation in two-rescuer CPR with a bag-valve-mask device during out-of-hospital cardiac arrest
Resuscitation, 77 (1), 57-62
DOI 10.1016/j.resuscitation.2007.11.005, PubMed 18164533 -
Progressing from initial non-shockable rhythms to a shockable rhythm is associated with improved outcome after out-of-hospital cardiac arrest
Resuscitation, 80 (1), 24-9
DOI 10.1016/j.resuscitation.2008.09.003, PubMed 19081664 -
Comprehensive evaluation for quality of prehospital CPR - Reply
Resuscitation, 78 (1), 99
DOI 10.1016/j.resuscitation.2007.12.002 -
Standard basic life support vs. continuous chest compressions only in out-of-hospital cardiac arrest
Acta Anaesthesiol Scand, 52 (7), 914-9
DOI 10.1111/j.1399-6576.2008.01723.x, PubMed 18702753 -
Axon tracing in the adult rat optic nerve and tract after intravitreal injection of MnDPDP using a semiautomatic segmentation technique
J Magn Reson Imaging, 27 (1), 34-42
DOI 10.1002/jmri.21234, PubMed 18157895 -
Prearrest administration of low-molecular-weight heparin in porcine cardiac arrest: hemodynamic effects and resuscitability
Crit Care Med, 36 (3), 881-6
DOI 10.1097/CCM.0B013E318164E781, PubMed 18431276 -
Automatic identification of return of spontaneous circulation during cardiopulmonary resuscitation
IEEE Trans Biomed Eng, 55 (1), 60-8
DOI 10.1109/TBME.2007.910644, PubMed 18232347 -
Dynamics and state transitions during resuscitation in out-of-hospital cardiac arrest
Resuscitation, 78 (1), 30-7
DOI 10.1016/j.resuscitation.2008.02.015, PubMed 18406035 -
Transthoracic impedance used to evaluate performance of cardiopulmonary resuscitation during out of hospital cardiac arrest
Resuscitation, 79 (3), 432-7
DOI 10.1016/j.resuscitation.2008.08.007, PubMed 19061785 -
Improving cardiopulmonary resuscitation quality to ensure survival
Curr Opin Crit Care, 14 (3), 299-304
DOI 10.1097/MCC.0b013e3282f827d3, PubMed 18467890 -
Differential regulation of AMP-activated kinase and AKT kinase in response to oxygen availability in crucian carp (Carassius carassius)
Am J Physiol Regul Integr Comp Physiol, 295 (6), R1803-14
DOI 10.1152/ajpregu.90590.2008, PubMed 18922957 -
Experimental and clinical use of ongoing mechanical cardiopulmonary resuscitation during angiography and percutaneous coronary intervention
Crit Care Med, 36 (11 Suppl), S405-8
DOI 10.1097/ccm.0b013e31818a7ee9, PubMed 20449901 -
Altered Na+/Ca2+-exchanger activity due to downregulation of Na+/K+-ATPase alpha2-isoform in heart failure
Cardiovasc Res, 78 (1), 71-8
DOI 10.1093/cvr/cvn013, PubMed 18203708 -
Altered Na(+)/Ca(2+)-exchanger activity due to downregulation of Na(+)/K(+)-ATPase alpha(2)-isoform in heart failure (vol 78, pg 71, 2008)
Cardiovasc. Res., 79 (2), 352
DOI 10.1093/cvr/cvn147 -
Therapeutic hypothermia after out-of hospital cardiac arrest: how to secure worldwide implementation
Curr Opin Anaesthesiol, 21 (2), 209-15
DOI 10.1097/ACO.0b013e3282f51d6d, PubMed 18443491
Publications 2007
-
Serotonin increases L-type Ca2+ current and SR Ca2+ content through 5-HT4 receptors in failing rat ventricular cardiomyocytes
Am J Physiol Heart Circ Physiol, 293 (4), H2367-76
DOI 10.1152/ajpheart.01375.2006, PubMed 17660386 -
Targeting heme-oxidized soluble guanylate cyclase in experimental heart failure
Hypertension, 49 (5), 1128-33
DOI 10.1161/HYPERTENSIONAHA.106.083832, PubMed 17325237 -
Standard versus over-the-head cardiopulmonary resuscitation during simulated advanced life support
Prehosp Emerg Care, 11 (4), 443-7
DOI 10.1080/00207450701537050, PubMed 17907030 -
Serotonin responsiveness through 5-HT2A and 5-HT4 receptors is differentially regulated in hypertrophic and failing rat cardiac ventricle
J Mol Cell Cardiol, 43 (6), 767-79
DOI 10.1016/j.yjmcc.2007.08.019, PubMed 17936780 -
Expression of mRNA encoding G protein-coupled receptors involved in congestive heart failure--a quantitative RT-PCR study and the question of normalisation
Basic Res Cardiol, 102 (3), 198-208
DOI 10.1007/s00395-007-0648-1, PubMed 17370034 -
Mineralocorticoid escape by the kidney but not the heart in experimental asymptomatic left ventricular dysfunction
Hypertension, 50 (3), 481-8
DOI 10.1161/HYPERTENSIONAHA.107.088534, PubMed 17635858 -
Shock outcome is related to prior rhythm and duration of ventricular fibrillation
Resuscitation, 75 (1), 60-7
DOI 10.1016/j.resuscitation.2007.02.014, PubMed 17467139 -
Continuous mechanical chest compressions during cardiac arrest to facilitate restoration of coronary circulation with percutaneous coronary intervention
J Am Coll Cardiol, 50 (11), 1093-4
DOI 10.1016/j.jacc.2007.05.028, PubMed 17825721 -
Cardiac accumulation of bone marrow mononuclear progenitor cells after intracoronary or intravenous injection in pigs subjected to acute myocardial infarction with subsequent reperfusion
Cardiovasc Revasc Med, 8 (1), 21-7
DOI 10.1016/j.carrev.2006.09.001, PubMed 17293265 -
Identifying approaches to improve the accuracy of shock outcome prediction for out-of-hospital cardiac arrest
Resuscitation, 76 (2), 279-84
DOI 10.1016/j.resuscitation.2007.07.019, PubMed 17767991 -
Immunoreactivity and guanosine 3',5'-cyclic monophosphate activating actions of various molecular forms of human B-type natriuretic peptide
Hypertension, 49 (5), 1114-9
DOI 10.1161/HYPERTENSIONAHA.106.081083, PubMed 17372040 -
Effects of preload alterations on peak early diastolic mitral annulus velocities evaluated by tissue Doppler echocardiography
Eur J Anaesthesiol, 24 (2), 159-65
DOI 10.1017/S026502150600127X, PubMed 17202014 -
[Nobel Prize for genetic modification]
Tidsskr Nor Laegeforen, 127 (23), 3054
PubMed 18049491 -
Detection of carbon dioxide in expired air after oesophageal intubation; the role of bystander mouth-to-mouth ventilation
Acta Anaesthesiol Scand, 52 (1), 155-7
DOI 10.1111/j.1399-6576.2007.01503.x, PubMed 17999713 -
Pauses in chest compression and inappropriate shocks: a comparison of manual and semi-automatic defibrillation attempts
Resuscitation, 73 (2), 212-20
DOI 10.1016/j.resuscitation.2006.09.006, PubMed 17241734 -
Uniform reporting of measured quality of cardiopulmonary resuscitation (CPR)
Resuscitation, 74 (3), 406-17
DOI 10.1016/j.resuscitation.2007.01.024, PubMed 17391831 -
Transthoracic impedance changes as a tool to detect malpositioned tracheal tubes
Resuscitation, 76 (1), 11-6
DOI 10.1016/j.resuscitation.2007.07.021, PubMed 17719166 -
Why Norwegian 2005 guidelines differs slightly from the ERC guidelines (vol 72, pg 490, 2007)
Resuscitation, 73 (3), 494
DOI 10.1016/j.resuscitation.2007.04.024 -
Exercise capacity and quality of life after intracoronary injection of autologous mononuclear bone marrow cells in acute myocardial infarction: results from the Autologous Stem cell Transplantation in Acute Myocardial Infarction (ASTAMI) randomized controlled trial
Am Heart J, 154 (4), 710.e1-8
DOI 10.1016/j.ahj.2007.07.003, PubMed 17892996 -
AKAP complex regulates Ca2+ re-uptake into heart sarcoplasmic reticulum
EMBO Rep, 8 (11), 1061-7
DOI 10.1038/sj.embor.7401081, PubMed 17901878 -
Increased cardiomyocyte function and Ca2+ transients in mice during early congestive heart failure
J Mol Cell Cardiol, 43 (2), 177-86
DOI 10.1016/j.yjmcc.2007.05.004, PubMed 17574269 -
Multiple inflammatory-, tissue remodelling- and fibrosis genes are differentially transcribed in the livers of Abcb4 (-/ - ) mice harbouring chronic cholangitis
Scand J Gastroenterol, 42 (10), 1245-55
DOI 10.1080/00365520701320521, PubMed 17852852 -
Prediction of countershock success using single features from multiple ventricular fibrillation frequency bands and feature combinations using neural networks
Resuscitation, 73 (2), 253-63
DOI 10.1016/j.resuscitation.2006.10.002, PubMed 17287063 -
Estimation of the duration of ventricular fibrillation using ECG single feature analysis
Resuscitation, 73 (2), 246-52
DOI 10.1016/j.resuscitation.2006.08.028, PubMed 17368907 -
A failed attempt to improve quality of out-of-hospital CPR through performance evaluation
Prehosp Emerg Care, 11 (4), 427-33
DOI 10.1080/10903120701536628, PubMed 17907028 -
Is CPR quality improving? A retrospective study of out-of-hospital cardiac arrest
Resuscitation, 75 (2), 260-6
DOI 10.1016/j.resuscitation.2007.04.016, PubMed 17560005 -
Quality of cardiopulmonary resuscitation before and during transport in out-of-hospital cardiac arrest
Resuscitation, 76 (2), 185-90
DOI 10.1016/j.resuscitation.2007.07.001, PubMed 17728039 -
[Therapeutic hypothermia--pharmacology and pathophysiology]
Tidsskr Nor Laegeforen, 127 (2), 163-6
PubMed 17237861 -
Arterial blood gases during basic life support of human cardiac arrest victims
Resuscitation, 77 (1), 35-8
DOI 10.1016/j.resuscitation.2007.10.005, PubMed 18035475 -
Misplaced and dislodged endotracheal tubes may be detected by the defibrillator during cardiopulmonary resuscitation
Acta Anaesthesiol Scand, 51 (6), 770-2
DOI 10.1111/j.1399-6576.2007.01317.x, PubMed 17465971 -
Grave acidosis after severe anaphylactic bronchospasm: friend or foe?
Acta Anaesthesiol Scand, 51 (4), 495-500
DOI 10.1111/j.1399-6576.2006.01223.x, PubMed 17229196 -
Comparison of hands-off time during CPR with manual and semi-automatic defibrillation in a manikin model
Resuscitation, 73 (1), 131-6
DOI 10.1016/j.resuscitation.2006.08.025, PubMed 17270336 -
A method to remove CPR artefacts from human ECG using only the recorded ECG
Resuscitation, 76 (2), 271-8
DOI 10.1016/j.resuscitation.2007.08.002, PubMed 17875356 -
Inhibition of T cell activation by cyclic adenosine 5'-monophosphate requires lipid raft targeting of protein kinase A type I by the A-kinase anchoring protein ezrin
J Immunol, 179 (8), 5159-68
DOI 10.4049/jimmunol.179.8.5159, PubMed 17911601 -
Predicting survival with good neurologic recovery at hospital admission after successful resuscitation of out-of-hospital cardiac arrest: the OHCA score
Eur Heart J, 28 (6), 773; author reply 773-4
DOI 10.1093/eurheartj/ehl536, PubMed 17314107 -
Implementation of a standardised treatment protocol for post resuscitation care after out-of-hospital cardiac arrest
Resuscitation, 73 (1), 29-39
DOI 10.1016/j.resuscitation.2006.08.016, PubMed 17258378 -
The Na+/K+-ATPase alpha2-isoform regulates cardiac contractility in rat cardiomyocytes
Cardiovasc Res, 75 (1), 109-17
DOI 10.1016/j.cardiores.2007.03.017, PubMed 17442282 -
Chest compressions by ambulance personnel on chests with variable stiffness: abilities and attitudes
Resuscitation, 74 (1), 127-34
DOI 10.1016/j.resuscitation.2006.12.006, PubMed 17368692
Publications 2006
-
Regulation of neuronal type genes in congestive heart failure rats
Acta Physiol (Oxf), 186 (1), 17-27
DOI 10.1111/j.1748-1716.2005.01503.x, PubMed 16497176 -
Lack of activation of molecular forms of the BNP system in human grade 1 hypertension and relationship to cardiac hypertrophy
Am J Physiol Heart Circ Physiol, 291 (4), H1529-35
DOI 10.1152/ajpheart.00107.2006, PubMed 16648193 -
Cross-reinnervation changes the expression patterns of the monocarboxylate transporters 1 and 4: An experimental study in slow and fast rat skeletal muscle
Neuroscience, 138 (4), 1105-13
DOI 10.1016/j.neuroscience.2005.12.014, PubMed 16446038 -
Effects of treatment with a 5-HT4 receptor antagonist in heart failure
Br J Pharmacol, 150 (2), 143-52
DOI 10.1038/sj.bjp.0706966, PubMed 17160012 -
Airway management by paramedics using endotracheal intubation with a laryngoscope versus the oesophageal tracheal Combitube and EasyTube on manikins: a randomised experimental trial
Resuscitation, 71 (1), 107-11
DOI 10.1016/j.resuscitation.2006.02.016, PubMed 16942827 -
Maximizing the renal cyclic 3'-5'-guanosine monophosphate system with type V phosphodiesterase inhibition and exogenous natriuretic peptide: a novel strategy to improve renal function in experimental overt heart failure
J Am Soc Nephrol, 17 (10), 2742-7
DOI 10.1681/ASN.2006020161, PubMed 16928803 -
Intact acute cardiorenal and humoral responsiveness following chronic subcutaneous administration of the cardiac peptide BNP in experimental heart failure
Eur J Heart Fail, 8 (7), 681-6
DOI 10.1016/j.ejheart.2005.12.005, PubMed 16459135 -
Effects of compression depth and pre-shock pauses predict defibrillation failure during cardiac arrest
Resuscitation, 71 (2), 137-45
DOI 10.1016/j.resuscitation.2006.04.008, PubMed 16982127 -
Activin A inhibits organization of sarcomeric proteins in cardiomyocytes induced by leukemia inhibitory factor
J Mol Cell Cardiol, 41 (4), 689-97
DOI 10.1016/j.yjmcc.2006.07.009, PubMed 16926021 -
Leukaemia inhibitory factor stimulates glucose transport in isolated cardiomyocytes and induces insulin resistance after chronic exposure
Diabetologia, 49 (4), 724-31
DOI 10.1007/s00125-006-0150-6, PubMed 16489447 -
The iodinated radiographic contrast medium iohexol mimics the vasodilator effect seen with small increases in extracellular K+ in the isolated rabbit central ear artery
Acta Radiol, 47 (7), 692-8
DOI 10.1080/02841850600806316, PubMed 16950707 -
Molecular basis of AKAP specificity for PKA regulatory subunits
Mol Cell, 24 (3), 383-95
DOI 10.1016/j.molcel.2006.09.006, PubMed 17081989 -
How to discriminate between hibernating and stunned myocardium
J Cardiovasc Surg (Torino), 47 (3), 323-8
PubMed 16760869 -
BNP-induced activation of cGMP in human cardiac fibroblasts: interactions with fibronectin and natriuretic peptide receptors
J Cell Physiol, 209 (3), 943-9
DOI 10.1002/jcp.20793, PubMed 16986166 -
The influence of a one-step reamer-irrigator-aspirator technique on the intramedullary pressure in the pig femur
Injury, 37 (10), 935-40
DOI 10.1016/j.injury.2006.06.119, PubMed 16934266 -
Ventricular fibrillation induced by ischemia-reperfusion is not prevented by the NPY Y2 receptor antagonist BIIE0246
J Cardiovasc Pharmacol Ther, 11 (3), 177-83
DOI 10.1177/1074248406292709, PubMed 17056830 -
Quality of out-of-hospital cardiopulmonary resuscitation with real time automated feedback: a prospective interventional study
Resuscitation, 71 (3), 283-92
DOI 10.1016/j.resuscitation.2006.05.011, PubMed 17070980 -
Reconfirmation algorithms should be the standard of care in automated external defibrillators
Resuscitation, 70 (3), 474-5; author reply 475
DOI 10.1016/j.resuscitation.2006.04.010, PubMed 16875772 -
Low-frequency oscillations of the laser Doppler perfusion signal in human skin
Microvasc Res, 72 (3), 120-7
DOI 10.1016/j.mvr.2006.05.006, PubMed 16854436 -
Regulation of human cutaneous circulation evaluated by laser Doppler flowmetry, iontophoresis, and spectral analysis: Importance of nitric oxide and prostaglandines (vol 65, pg 160, 2003)
Microvasc. Res., 71 (3), 227
DOI 10.1016/j.mvr.2005.11.001 -
Alveolar hypoxia induces left ventricular diastolic dysfunction and reduces phosphorylation of phospholamban in mice
Am J Physiol Heart Circ Physiol, 291 (2), H507-16
DOI 10.1152/ajpheart.00862.2005, PubMed 16582020 -
Why Norwegian 2005 guidelines differs slightly from the ERC guidelines
Resuscitation, 72 (3), 490-2
DOI 10.1016/j.resuscitation.2006.07.018, PubMed 17161898 -
Contribution of the Na+/Ca2+ exchanger to rapid Ca2+ release in cardiomyocytes
Biophys J, 91 (3), 779-92
DOI 10.1529/biophysj.105.072447, PubMed 16679359 -
T-tubule disorganization and reduced synchrony of Ca2+ release in murine cardiomyocytes following myocardial infarction
J Physiol, 574 (Pt 2), 519-33
DOI 10.1113/jphysiol.2006.107227, PubMed 16709642 -
Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction
N Engl J Med, 355 (12), 1199-209
DOI 10.1056/NEJMoa055706, PubMed 16990383 -
Effects of congestive heart failure on Ca2+ handling in skeletal muscle during fatigue
Circ Res, 98 (12), 1514-9
DOI 10.1161/01.RES.0000226529.66545.e5, PubMed 16690878 -
[Research and research education are important]
Tidsskr Nor Laegeforen, 126 (11), 1495-6
PubMed 16732347 -
Time course of degradation of cardiac troponin I in patients with acute ST-elevation myocardial infarction: the ASSENT-2 troponin substudy
Circ Res, 99 (10), 1141-7
DOI 10.1161/01.RES.0000249531.23654.e1, PubMed 17038641 -
Amino-terminal pro-B-type natriuretic peptide and B-type natriuretic peptide: biomarkers for mortality in a large community-based cohort free of heart failure
Hypertension, 47 (5), 874-80
DOI 10.1161/01.HYP.0000216794.24161.8c, PubMed 16585413 -
Quality of lay person CPR performance with compression: ventilation ratios 15:2, 30:2 or continuous chest compressions without ventilations on manikins
Resuscitation, 71 (3), 335-40
DOI 10.1016/j.resuscitation.2006.05.012, PubMed 17069958 -
Haemodynamic effects of adrenaline (epinephrine) depend on chest compression quality during cardiopulmonary resuscitation in pigs
Resuscitation, 71 (3), 369-78
DOI 10.1016/j.resuscitation.2006.05.003, PubMed 17023108 -
Characterization of A-kinase-anchoring disruptors using a solution-based assay
Biochem J, 400 (3), 493-9
DOI 10.1042/BJ20060962, PubMed 16948636 -
Determination of prognosis after cardiac arrest may be more difficult after introduction of therapeutic hypothermia
Resuscitation, 69 (1), 29-32
DOI 10.1016/j.resuscitation.2005.12.003, PubMed 16517042 -
Slow diffusion of K+ in the T tubules of rat cardiomyocytes
J Appl Physiol (1985), 101 (4), 1170-6
DOI 10.1152/japplphysiol.00297.2006, PubMed 16763106 -
Compression force-depth relationship during out-of-hospital cardiopulmonary resuscitation
Resuscitation, 72 (3), 364-70
DOI 10.1016/j.resuscitation.2006.07.017, PubMed 17141936
Publications 2005
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Cardiac fibrinolytic capacity is markedly increased after brief periods of local myocardial ischemia, but declines following successive periods in anesthetized pigs
J Thromb Haemost, 3 (9), 1947-54
DOI 10.1111/j.1538-7836.2005.01514.x, PubMed 16102101 -
EC-coupling in normal and failing hearts
Scand Cardiovasc J, 39 (1-2), 13-23
DOI 10.1080/14017430410004632, PubMed 16097409 -
Artifactual contractions triggered by field stimulation of cardiomyocytes
J Appl Physiol (1985), 98 (5), 1712-9
DOI 10.1152/japplphysiol.00630.2004, PubMed 15640393 -
pH dependent uptake of porphyrin-type photosensitizers by solid tumor cells in vitro is not induced by modification of transmembrane potential
Cancer Lett, 222 (1), 39-47
DOI 10.1016/j.canlet.2004.09.032, PubMed 15837539 -
Independent evaluation of a defibrillation outcome predictor for out-of-hospital cardiac arrested patients
Resuscitation, 67 (1), 55-61
DOI 10.1016/j.resuscitation.2005.05.006, PubMed 16154680 -
Reducing no flow times during automated external defibrillation
Resuscitation, 67 (1), 95-101
DOI 10.1016/j.resuscitation.2005.04.009, PubMed 16154679 -
Quantitative mass spectral evidence for the absence of circulating brain natriuretic peptide (BNP-32) in severe human heart failure
Proc Natl Acad Sci U S A, 102 (48), 17442-7
DOI 10.1073/pnas.0508782102, PubMed 16293687 -
Reduced release of vasoconstrictors from the porcine heart after repeated periods of ischemia
Scand Cardiovasc J, 39 (1-2), 60-6
DOI 10.1080/14017430510009041, PubMed 16097416 -
Influence of endogenous neuropeptide Y (NPY) on the sympathetic-parasympathetic interaction in the canine heart
J Cardiovasc Pharmacol, 46 (4), 474-80
DOI 10.1097/01.fjc.0000177986.21929.d8, PubMed 16160600 -
Reduced immune responses to an aseptic inflammation in mice with congestive heart failure
Eur J Haematol, 75 (2), 156-63
DOI 10.1111/j.1600-0609.2005.00440.x, PubMed 16000132 -
Congestive heart failure: pharmacological agents and the potential of B-type natriuretic Peptide
Curr Med Chem, 12 (12), 1439-47
DOI 10.2174/0929867054020909, PubMed 15974994 -
Predicting outcome after cardiac arrest: two caveats
Resuscitation, 66 (1), 108-9; author reply 109-10
DOI 10.1016/j.resuscitation.2004.12.028, PubMed 15993739 -
Advanced cardiac life support before and after tracheal intubation--direct measurements of quality
Resuscitation, 68 (1), 61-9
DOI 10.1016/j.resuscitation.2005.05.020, PubMed 16325329 -
A fast and sensitive method for isolation of detergent-resistant membranes from T cells
J Immunol Methods, 305 (2), 199-205
DOI 10.1016/j.jim.2005.06.011, PubMed 16176818 -
Natriuretic and antialdosterone actions of chronic oral NEP inhibition during progressive congestive heart failure
Kidney Int, 67 (5), 1723-30
DOI 10.1111/j.1523-1755.2005.00269.x, PubMed 15840018 -
Appearance of a ventricular 5-HT4 receptor-mediated inotropic response to serotonin in heart failure
Cardiovasc Res, 65 (4), 869-78
DOI 10.1016/j.cardiores.2004.11.017, PubMed 15721867 -
Rationale for treatment of heart failure by blockade of ventricular serotonin receptors appearing in heart failure
PROCEEDINGS OF THE 25TH EUROPEAN SECTION MEETING INTERNATIONAL SOCIETY FOR HEART RESEARCH, 7-12 -
Dual serotonergic regulation of ventricular contractile force through 5-HT2A and 5-HT4 receptors induced in the acute failing heart
Circ Res, 97 (3), 268-76
DOI 10.1161/01.RES.0000176970.22603.8d, PubMed 16002744 -
Carvedilol blockade of alpha1- and beta-adrenoceptor induced inotropic responses in rats with congestive heart failure
Eur J Pharmacol, 516 (1), 51-9
DOI 10.1016/j.ejphar.2005.04.027, PubMed 15916756 -
Differential regulation of vacuolar H+ -ATPase and Na+/H+ exchanger 3 in rat cholangiocytes after bile duct ligation
Histochem Cell Biol, 125 (4), 419-28
DOI 10.1007/s00418-005-0082-0, PubMed 16267653 -
Enhanced matrix metalloproteinase activity in skeletal muscles of rats with congestive heart failure
Am J Physiol Regul Integr Comp Physiol, 289 (2), R389-R394
DOI 10.1152/ajpregu.00067.2005, PubMed 15802562 -
Defective excitation-contraction coupling in hearts of rats with congestive heart failure
Acta Physiol Scand, 184 (1), 45-58
DOI 10.1111/j.1365-201X.2005.01431.x, PubMed 15847643 -
Impaired Ca2+ handling and contraction in cardiomyocytes from mice with a dominant negative thyroid hormone receptor alpha1
J Mol Cell Cardiol, 38 (4), 655-63
DOI 10.1016/j.yjmcc.2005.02.008, PubMed 15808842 -
Temperature-dependent skeletal muscle dysfunction in rats with congestive heart failure
J Appl Physiol (1985), 99 (4), 1500-7
DOI 10.1152/japplphysiol.00807.2004, PubMed 15932960 -
Manganese-enhanced MRI of the optic visual pathway and optic nerve injury in adult rats
J Magn Reson Imaging, 22 (4), 492-500
DOI 10.1002/jmri.20400, PubMed 16161073 -
Dysregulated osteoprotegerin/RANK ligand/RANK axis in clinical and experimental heart failure
Circulation, 111 (19), 2461-8
DOI 10.1161/01.CIR.0000165119.62099.14, PubMed 15883214 -
Cardiac arrest and resuscitation with an automatic mechanical chest compression device (LUCAS) due to anaphylaxis of a woman receiving caesarean section because of pre-eclampsia
Resuscitation, 68 (1), 155-9
DOI 10.1016/j.resuscitation.2005.06.001, PubMed 16221521 -
Use of an automatic mechanical chest compression device (LUCAS) as a bridge to establishing cardiopulmonary bypass for a patient with hypothermic cardiac arrest
Resuscitation, 66 (3), 391-4
DOI 10.1016/j.resuscitation.2005.03.011, PubMed 15992987 -
Quality of cardiopulmonary resuscitation during out-of-hospital cardiac arrest
JAMA, 293 (3), 299-304
DOI 10.1001/jama.293.3.299, PubMed 15657322 -
Twelve-month retention of CPR skills with automatic correcting verbal feedback
Resuscitation, 66 (1), 27-30
DOI 10.1016/j.resuscitation.2004.12.022, PubMed 15993726 -
Daily administration of interleukin-18 causes myocardial dysfunction in healthy mice
Am J Physiol Heart Circ Physiol, 289 (2), H708-14
DOI 10.1152/ajpheart.01179.2004, PubMed 15821032
Publications 2004
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Equimolar doses of atrial and brain natriuretic peptides and urodilatin have differential renal actions in overt experimental heart failure
Am J Physiol Regul Integr Comp Physiol, 288 (5), R1093-7
DOI 10.1152/ajpregu.00682.2004, PubMed 15627648 -
Comparison of nonviral transfection and adeno-associated viral transduction on cardiomyocytes
Mol Biotechnol, 28 (1), 21-32
DOI 10.1385/MB:28:1:21, PubMed 15456960 -
Arterial blood gases with 700 ml tidal volumes during out-of-hospital CPR
Resuscitation, 61 (1), 23-7
DOI 10.1016/j.resuscitation.2003.12.017, PubMed 15081177 -
Oxygen delivery and return of spontaneous circulation with ventilation:compression ratio 2:30 versus chest compressions only CPR in pigs
Resuscitation, 60 (3), 309-18
DOI 10.1016/j.resuscitation.2003.12.001, PubMed 15050764 -
Frequency-dependent and proarrhythmogenic effects of FK-506 in rat ventricular cells
Am J Physiol Heart Circ Physiol, 288 (2), H778-86
DOI 10.1152/ajpheart.00542.2004, PubMed 15471978 -
Echocardiographic parameters discriminating myocardial infarction with pulmonary congestion from myocardial infarction without congestion in the mouse
J Appl Physiol (1985), 98 (2), 680-9
DOI 10.1152/japplphysiol.00924.2004, PubMed 15475595 -
Increased syndecan expression following myocardial infarction indicates a role in cardiac remodeling
Physiol Genomics, 16 (3), 301-8
DOI 10.1152/physiolgenomics.00144.2002, PubMed 14625378 -
Leukaemia inhibitory factor alters expression of genes involved in rat cardiomyocyte energy metabolism
Acta Physiol Scand, 180 (2), 133-42
DOI 10.1046/j.0001-6772.2003.01245.x, PubMed 14738472 -
Leukemia inhibitory factor reduces contractile function and induces alterations in energy metabolism in isolated cardiomyocytes
J Mol Cell Cardiol, 37 (6), 1183-93
DOI 10.1016/j.yjmcc.2004.09.008, PubMed 15572048 -
Pentobarbital versus medetomidine-ketamine-fentanyl anaesthesia: effects on haemodynamics and the incidence of ischaemia-induced ventricular fibrillation in swine
Lab Anim, 38 (1), 70-8
DOI 10.1258/00236770460734425, PubMed 14979991 -
MRI of slow flow in artificial duct in swine
Eur Radiol, 14 (9), 1692-7
DOI 10.1007/s00330-003-2212-1, PubMed 14767600 -
Sevoflurane-induced malignant hyperthermia during cardiopulmonary bypass and moderate hypothermia
Acta Anaesthesiol Scand, 48 (8), 1062-5
DOI 10.1111/j.0001-5172.2004.00451.x, PubMed 15315628 -
Diagnostic approach to the patient with jaundice following trauma
Scand J Surg, 93 (3), 176-83
DOI 10.1177/145749690409300302, PubMed 15544071 -
Increased spillover of norepinephrine to the portal vein during CO-pneumoperitoneum in pigs
Acta Anaesthesiol Scand, 48 (4), 443-50
DOI 10.1111/j.0001-5172.2004.00366.x, PubMed 15025606 -
Heart valve calcifications, survival, and cardiovascular risk in hemodialysis patients
Am J Kidney Dis, 43 (3), 479-84
DOI 10.1053/j.ajkd.2003.11.009, PubMed 14981606 -
Myelin-, reactive glia-, and scar-derived CNS axon growth inhibitors: expression, receptor signaling, and correlation with axon regeneration
Glia, 46 (3), 225-51
DOI 10.1002/glia.10315, PubMed 15048847 -
Muscle dysfunction during exercise of a single skeletal muscle in rats with congestive heart failure is not associated with reduced muscle blood supply
Acta Physiol Scand, 181 (2), 173-81
DOI 10.1111/j.1365-201X.2004.01285.x, PubMed 15180789 -
Comparison of short- and long-duration oxygen treatment after cerebral asphyxia in newborn piglets
Pediatr Res, 56 (1), 125-31
DOI 10.1203/01.PDR.0000128978.90201.1D, PubMed 15128930 -
Rapid extrication from a car wreck
Injury, 35 (8), 739-45
DOI 10.1016/j.injury.2004.01.003, PubMed 15246795 -
Elevated levels of activin A in heart failure: potential role in myocardial remodeling
Circulation, 109 (11), 1379-85
DOI 10.1161/01.CIR.0000120704.97934.41, PubMed 14993131 -
Prognostic value of echocardiographic indicators of left ventricular systolic function in asymptomatic dialysis patients
J Am Soc Nephrol, 15 (4), 1029-37
DOI 10.1097/01.asn.0000117977.14912.91, PubMed 15034106 -
Left ventricular mass monitoring in the follow-up of dialysis patients: prognostic value of left ventricular hypertrophy progression
Kidney Int, 65 (4), 1492-8
DOI 10.1111/j.1523-1755.2004.00530.x, PubMed 15086493
Publications 2003
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Cardiorenal and humoral properties of a novel direct soluble guanylate cyclase stimulator BAY 41-2272 in experimental congestive heart failure
Circulation, 107 (5), 686-9
DOI 10.1161/01.cir.0000055737.15443.f8, PubMed 12578869 -
Angiotensin II AT1 receptor antagonism prevents detrimental renal actions of acute diuretic therapy in human heart failure
Am J Physiol Renal Physiol, 284 (5), F1115-9
DOI 10.1152/ajprenal.00337.2002, PubMed 12676739 -
Embryonic and neonatal cardiac gene transfer in vivo
Methods Mol Biol, 219, 169-78
DOI 10.1385/1-59259-350-x:169, PubMed 12597007 -
Dispatcher-assisted cardiopulmonary resuscitation. An evaluation of efficacy amongst elderly
Resuscitation, 56 (3), 265-73
DOI 10.1016/s0300-9572(02)00374-x, PubMed 12628557 -
Quality of CPR with three different ventilation:compression ratios
Resuscitation, 58 (2), 193-201
DOI 10.1016/s0300-9572(03)00125-4, PubMed 12909382 -
Protein kinase A-anchoring protein AKAP95 interacts with MCM2, a regulator of DNA replication
J Biol Chem, 278 (29), 26750-6
DOI 10.1074/jbc.M300765200, PubMed 12740381 -
Cardiac output, pulmonary artery pressure, and patent ductus arteriosus during therapeutic cooling after global hypoxia-ischaemia
Arch Dis Child Fetal Neonatal Ed, 88 (3), F223-8
DOI 10.1136/fn.88.3.f223, PubMed 12719397 -
Merlin links to the cAMP neuronal signaling pathway by anchoring the RIbeta subunit of protein kinase A
J Biol Chem, 278 (42), 41167-72
DOI 10.1074/jbc.M306149200, PubMed 12896975 -
Isometric force and endurance in skeletal muscle of mice devoid of all known thyroid hormone receptors
J Physiol, 547 (Pt 3), 789-96
DOI 10.1113/jphysiol.2002.032086, PubMed 12562961 -
Leukemia inhibitory factor is augmented in the heart in experimental heart failure
Eur J Heart Fail, 5 (2), 137-45
DOI 10.1016/s1388-9842(02)00236-2, PubMed 12644003 -
Ventricular cardiotrophin-1 activation precedes BNP in experimental heart failure
Peptides, 24 (6), 889-92
DOI 10.1016/s0196-9781(03)00163-3, PubMed 12948841 -
Distribution of neuropeptide Y Y1 and Y2 receptors in the postmortem human heart
Peptides, 24 (2), 255-62
DOI 10.1016/s0196-9781(03)00041-x, PubMed 12668210 -
Kinetic model of osmosis through semipermeable and solute-permeable membranes
Acta Physiol Scand, 177 (2), 107-17
DOI 10.1046/j.1365-201X.2003.01062.x, PubMed 12558549 -
Analysis of energy metabolism and mechanism of loop diuretics in the thick ascending limb of Henle's loop in dog kidneys
Acta Physiol Scand, 178 (1), 73-82
DOI 10.1046/j.1365-201X.2003.01058.x, PubMed 12713517 -
Regulation of human cutaneous circulation evaluated by laser Doppler flowmetry, iontophoresis, and spectral analysis: importance of nitric oxide and prostaglandines
Microvasc Res, 65 (3), 160-71
DOI 10.1016/s0026-2862(03)00006-2, PubMed 12711257 -
Enhanced endothelial activity reflected in cutaneous blood flow oscillations of athletes
Eur J Appl Physiol, 90 (1-2), 16-22
DOI 10.1007/s00421-003-0867-6, PubMed 12783233 -
Aetiology and prognostic implication of severe jaundice in surgical trauma patients
Scand J Gastroenterol, 38 (1), 102-8
DOI 10.1080/00365520310000519, PubMed 12608472 -
In-hospital factors associated with improved outcome after out-of-hospital cardiac arrest. A comparison between four regions in Norway
Resuscitation, 56 (3), 247-63
DOI 10.1016/s0300-9572(02)00409-4, PubMed 12628556 -
Myocardial extracellular signal regulatory kinases are activated by laser treatment
J Cardiovasc Surg (Torino), 44 (1), 1-7
PubMed 12627065 -
Hepatocyte growth factor and left ventricular geometry in end-stage renal disease
Hypertension, 41 (1), 88-92
DOI 10.1161/01.hyp.0000046919.41112.4b, PubMed 12511535 -
Carvedilol blockade of rat myocardial alpha1-adrenoceptors
Eur J Pharmacol, 481 (1), 83-9
DOI 10.1016/j.ejphar.2003.09.001, PubMed 14637179 -
Effect of global hypoxia-ischaemia followed by 24 h of mild hypothermia on organ pathology and biochemistry in a newborn pig survival model
Biol Neonate, 83 (2), 146-56
DOI 10.1159/000067958, PubMed 12576759 -
Endothelin A receptor antagonism in experimental congestive heart failure results in augmentation of the renin-angiotensin system and sustained sodium retention
Circulation, 109 (2), 249-54
DOI 10.1161/01.CIR.0000109139.69775.EB, PubMed 14691038 -
Increased contribution of alpha 1- vs. beta-adrenoceptor-mediated inotropic response in rats with congestive heart failure
Acta Physiol Scand, 177 (4), 449-58
DOI 10.1046/j.1365-201X.2003.01063.x, PubMed 12648162 -
Heart failure -- a challenge to our current concepts of excitation-contraction coupling
J Physiol, 546 (Pt 1), 33-47
DOI 10.1113/jphysiol.2002.034728, PubMed 12509477 -
[Does altered regulation of Na+ cause reduced myocardial contractility in heart failure?]
Tidsskr Nor Laegeforen, 123 (21), 3036-40
PubMed 14618171 -
Localization and function of the Na+/Ca2+-exchanger in normal and detubulated rat cardiomyocytes
J Mol Cell Cardiol, 35 (11), 1325-37
DOI 10.1016/j.yjmcc.2003.08.005, PubMed 14596789 -
Ventricular adrenomedullin is associated with myocyte hypertrophy in human transplanted heart
Regul Pept, 112 (1-3), 161-6
DOI 10.1016/s0167-0115(03)00035-1, PubMed 12667638 -
Comparison of pulmonary and inflammatory effects of lipid- and water-soluble components in meconium in newborn piglets
Biol Neonate, 84 (4), 330-7
DOI 10.1159/000073643, PubMed 14593245 -
Cardiopulmonary alterations in mRNA expression for interleukin-1beta, the interleukin-6 superfamily and CXC-chemokines during development of postischaemic heart failure in the rat
Clin Physiol Funct Imaging, 23 (5), 263-8
DOI 10.1046/j.1475-097x.2003.00503.x, PubMed 12950323 -
Evaluation of a defibrillator-basic cardiopulmonary resuscitation programme for non medical personnel
Resuscitation, 56 (2), 167-72
DOI 10.1016/s0300-9572(02)00351-9, PubMed 12589990 -
Delaying defibrillation to give basic cardiopulmonary resuscitation to patients with out-of-hospital ventricular fibrillation: a randomized trial
JAMA, 289 (11), 1389-95
DOI 10.1001/jama.289.11.1389, PubMed 12636461 -
Evaluation of a new fiber-optic pressure recording system for cardiovascular measurements in mice
Am J Physiol Heart Circ Physiol, 285 (5), H2233-9
DOI 10.1152/ajpheart.01123.2002, PubMed 12829434 -
Increased cardiac IL-18 mRNA, pro-IL-18 and plasma IL-18 after myocardial infarction in the mouse; a potential role in cardiac dysfunction
Cardiovasc Res, 59 (1), 122-31
DOI 10.1016/s0008-6363(03)00339-0, PubMed 12829183 -
Neuropeptide Y, left ventricular mass and function in patients with end stage renal disease
J Hypertens, 21 (7), 1355-62
DOI 10.1097/00004872-200307000-00025, PubMed 12817184 -
Prospective study of neuropeptide y as an adverse cardiovascular risk factor in end-stage renal disease
J Am Soc Nephrol, 14 (10), 2611-7
DOI 10.1097/01.asn.0000089026.28617.33, PubMed 14514739
Publications 2002
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Pediatric excretory MR urography: comparative study of enhanced and non-enhanced techniques
Eur Radiol, 13 (6), 1423-7
DOI 10.1007/s00330-002-1750-2, PubMed 12764661 -
Changes of protein kinetics in nephrotic patients
Curr Opin Clin Nutr Metab Care, 5 (1), 51-4
DOI 10.1097/00075197-200201000-00010, PubMed 11790950 -
Effectiveness of ventilation-compression ratios 1:5 and 2:15 in simulated single rescuer paediatric resuscitation
Resuscitation, 54 (3), 259-64
DOI 10.1016/s0300-9572(02)00147-8, PubMed 12204459 -
Distinct but overlapping domains of AKAP95 are implicated in chromosome condensation and condensin targeting
EMBO Rep, 3 (5), 426-32
DOI 10.1093/embo-reports/kvf089, PubMed 11964380 -
Leukotriene antagonism reduces the generation of endothelin-1 and interferon-gamma and inhibits eosinophilic airway inflammation
Respir Med, 96 (11), 901-6
DOI 10.1053/rmed.2002.1375, PubMed 12418588 -
Prolonged apneas and hypoxia mediated by nicotine and endotoxin in piglets
Biol Neonate, 81 (2), 119-25
DOI 10.1159/000047196, PubMed 11844882 -
Decreased hematopoiesis in bone marrow of mice with congestive heart failure
Am J Physiol Regul Integr Comp Physiol, 282 (1), R166-72
DOI 10.1152/ajpregu.2002.282.1.R166, PubMed 11742835 -
Cardiac energetics in congestive heart failure - Response
Circulation, 105 (6), E44-E45 -
Cardiotrophin-1 stimulates endothelin-1 via gp130 in vascular endothelial cells
Peptides, 23 (8), 1441-7
DOI 10.1016/s0196-9781(02)00078-5, PubMed 12182945 -
Analysis of the tubuloglomerular feedback mechanism in renal autoregulation
Acta Physiol Scand, 174 (4), 357-66
DOI 10.1046/j.1365-201x.2002.00969.x, PubMed 11942923 -
Mechanisms of intercellular hypertonicity and isotonic fluid absorption in proximal tubules of mammalian kidneys
Acta Physiol Scand, 175 (1), 71-83
DOI 10.1046/j.1365-201X.2002.00973.x, PubMed 11982506 -
Analysis of myogenic mechanisms in renal autoregulation
Acta Physiol Scand, 174 (4), 347-55
DOI 10.1046/j.1365-201x.2002.00966.x, PubMed 11942922 -
Mechanisms of transjunctional transport of NaCl and water in proximal tubules of mammalian kidneys
Acta Physiol Scand, 175 (1), 55-70
DOI 10.1046/j.1365-201X.2002.00967.x, PubMed 11982505 -
Cholestatic effect of large bilirubin loads and cholestasis protection conferred by cholic acid co-infusion: a molecular and ultrastructural study
Scand J Gastroenterol, 37 (5), 585-96
DOI 10.1080/00365520252903152, PubMed 12059062 -
Inspiratory impedance threshold valve during CPR
Resuscitation, 52 (1), 39-48
DOI 10.1016/s0300-9572(01)00442-7, PubMed 11801347 -
Contractile properties of in situ perfused skeletal muscles from rats with congestive heart failure
J Physiol, 540 (Pt 2), 571-80
DOI 10.1113/jphysiol.2001.013324, PubMed 11956344 -
Physical mapping of the Bacillus thuringiensis subsp. kurstaki and alesti chromosomes
Curr Microbiol, 44 (2), 81-7
DOI 10.1007/s00284-001-0055-z, PubMed 11815850 -
Hyperhomocysteinemia predicts cardiovascular outcomes in hemodialysis patients
Kidney Int, 61 (2), 609-14
DOI 10.1046/j.1523-1755.2002.00144.x, PubMed 11849403 -
Reduced level of serine(16) phosphorylated phospholamban in the failing rat myocardium: a major contributor to reduced SERCA2 activity
Cardiovasc Res, 53 (2), 382-91
DOI 10.1016/s0008-6363(01)00489-8, PubMed 11827689 -
Surgical manipulation, but not moderate exercise, is associated with increased cytokine mRNA expression in the rat soleus muscle
Acta Physiol Scand, 175 (3), 219-26
DOI 10.1046/j.1365-201X.2002.00990.x, PubMed 12100361 -
Reduced calcium tolerance in rat cardiomyocytes after myocardial infarction
Acta Physiol Scand, 175 (4), 261-9
DOI 10.1046/j.1365-201X.2002.00999.x, PubMed 12167165 -
Normal contractions triggered by I(Ca,L) in ventricular myocytes from rats with postinfarction CHF
Am J Physiol Heart Circ Physiol, 283 (3), H1225-36
DOI 10.1152/ajpheart.00162.2001, PubMed 12181154 -
Preconditioning - endogenous defence mechanisms of the heart
Acta Anaesthesiol Scand, 46 (2), 123-37
DOI 10.1034/j.1399-6576.2002.460202.x, PubMed 11942859 -
A serious threat to evidence based resuscitation within the European Union
Resuscitation, 53 (3), 237-8
DOI 10.1016/s0300-9572(02)00103-x, PubMed 12062833 -
Brain natriuretic Peptide is produced in cardiac fibroblasts and induces matrix metalloproteinases
Circ Res, 91 (12), 1127-34
DOI 10.1161/01.res.0000046234.73401.70, PubMed 12480813 -
Cardiotrophin-1 stimulation of cardiac fibroblast growth: roles for glycoprotein 130/leukemia inhibitory factor receptor and the endothelin type A receptor
Circ Res, 90 (2), 128-34
DOI 10.1161/hh0202.103613, PubMed 11834704 -
Molecular medicine for the cardiac surgeon
Scand Cardiovasc J, 36 (4), 201-8
DOI 10.1080/14017430260180346, PubMed 12201966 -
Retention of basic life support skills 6 months after training with an automated voice advisory manikin system without instructor involvement
Resuscitation, 52 (3), 273-9
DOI 10.1016/s0300-9572(01)00476-2, PubMed 11886733 -
Gene expression of colony-stimulating factors and stem cell factor after myocardial infarction in the mouse
Acta Physiol Scand, 175 (3), 173-81
DOI 10.1046/j.1365-201X.2002.00989.x, PubMed 12100356 -
Left ventricular hypertrophy, cardiac remodeling and asymmetric dimethylarginine (ADMA) in hemodialysis patients
Kidney Int, 62 (1), 339-45
DOI 10.1046/j.1523-1755.2002.00437.x, PubMed 12081596 -
Plasma norepinephrine predicts survival and incident cardiovascular events in patients with end-stage renal disease
Circulation, 105 (11), 1354-9
DOI 10.1161/hc1102.105261, PubMed 11901048 -
Norepinephrine and concentric hypertrophy in patients with end-stage renal disease
Hypertension, 40 (1), 41-6
DOI 10.1161/01.hyp.0000022063.50739.60, PubMed 12105136
Publications 2001
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Monocyte chemoattractant protein-1 enhances and interleukin-10 suppresses the production of inflammatory cytokines in adult rat cardiomyocytes
Basic Res Cardiol, 96 (4), 345-52
DOI 10.1007/s003950170042, PubMed 11518190 -
Myocardial gene expression of leukaemia inhibitory factor, interleukin-6 and glycoprotein 130 in end-stage human heart failure
Eur J Clin Invest, 31 (5), 389-97
DOI 10.1046/j.1365-2362.2001.00795.x, PubMed 11380590 -
Effect of endothelin antagonism on the production of cytokines in eosinophilic airway inflammation
Am J Physiol Lung Cell Mol Physiol, 280 (4), L659-65
DOI 10.1152/ajplung.2001.280.4.L659, PubMed 11238005 -
Upregulation of the cardiac monocarboxylate transporter MCT1 in a rat model of congestive heart failure
Circulation, 104 (6), 729-34
DOI 10.1161/hc3201.092286, PubMed 11489783 -
Cardioprotective effects of the MR contrast agent MnDPDP and its metabolite MnPLED upon reperfusion of the ischemic porcine myocardium
Acta Radiol, 42 (6), 540-7
DOI 10.1080/028418501127347340, PubMed 11736698 -
Reducing CPR artefacts in ventricular fibrillation in vitro
Resuscitation, 48 (3), 279-91
DOI 10.1016/s0300-9572(00)00259-8, PubMed 11278094 -
Quantitative assessment of myocardial perfusion during graded coronary artery stenoses by intravenous myocardial contrast echocardiography
J Am Coll Cardiol, 37 (2), 624-31
DOI 10.1016/s0735-1097(00)01127-x, PubMed 11216989 -
Contraction and intracellular Ca(2+) handling in isolated skeletal muscle of rats with congestive heart failure
Circ Res, 88 (12), 1299-305
DOI 10.1161/hh1201.092041, PubMed 11420307 -
Skeletal muscle disorders in heart failure
Acta Physiol Scand, 171 (3), 277-94
DOI 10.1046/j.1365-201x.2001.00830.x, PubMed 11412140 -
Autoimmunity against the ryanodine receptor in myasthenia gravis
Acta Physiol Scand, 171 (3), 379-84
DOI 10.1046/j.1365-201x.2001.00841.x, PubMed 11412151 -
Temporal evolution of nonlinear dynamics in ventricular arrhythmia
Int. J. Bifurcation Chaos, 11 (10), 2531-2548
DOI 10.1142/S0218127401003590 -
Untitled - Response to Heimlich and Spletzer
Resuscitation, 48 (2), 186-187
DOI 10.1016/S0300-9572(00)00332-4 -
Muscle contractile properties during intermittent nontetanic stimulation in rat skeletal muscle
Am J Physiol Regul Integr Comp Physiol, 281 (6), R1952-65
DOI 10.1152/ajpregu.2001.281.6.R1952, PubMed 11705782 -
An automated voice advisory manikin system for training in basic life support without an instructor. A novel approach to CPR training
Resuscitation, 50 (2), 167-72
DOI 10.1016/s0300-9572(01)00331-8, PubMed 11719144 -
Myocardial laser revascularization in the year 2000 as seen by a Norwegian specialist panel. The process of evaluating and implementing new methods in clinical practice
Scand Cardiovasc J, 35 (1), 14-8
DOI 10.1080/140174301750101384, PubMed 11354565
Publications 2000
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High-efficiency, long-term cardiac expression of foreign genes in living mouse embryos and neonates
Circulation, 101 (2), 178-84
DOI 10.1161/01.cir.101.2.178, PubMed 10637206 -
Myocardial expression of CC- and CXC-chemokines and their receptors in human end-stage heart failure
Cardiovasc Res, 47 (4), 778-87
DOI 10.1016/s0008-6363(00)00142-5, PubMed 10974226 -
Predicting outcome of defibrillation by spectral characterization and nonparametric classification of ventricular fibrillation in patients with out-of-hospital cardiac arrest
Circulation, 102 (13), 1523-9
DOI 10.1161/01.cir.102.13.1523, PubMed 11004143 -
Endothelin-1 production is associated with eosinophilic rather than neutrophilic airway inflammation
Eur Respir J, 15 (4), 743-50
DOI 10.1034/j.1399-3003.2000.15d19.x, PubMed 10780768 -
Isometric force and endurance in soleus muscle of thyroid hormone receptor-alpha(1)- or -beta-deficient mice
Am J Physiol Regul Integr Comp Physiol, 278 (3), R598-603
DOI 10.1152/ajpregu.2000.278.3.R598, PubMed 10712278 -
Intravenous bilirubin, dibromosulfophthalein, and bromosulfophthalein infusions uncouple biliary phospholipid and cholesterol secretion from bile acid secretion by inhibiting hepatic phosphoglycoprotein-3 activity in pigs
Scand J Gastroenterol, 35 (8), 873-82
DOI 10.1080/003655200750023264, PubMed 10994628 -
Airway pressure with chest compressions versus Heimlich manoeuvre in recently dead adults with complete airway obstruction
Resuscitation, 44 (2), 105-8
DOI 10.1016/s0300-9572(00)00161-1, PubMed 10767497 -
Arterial blood-gases with 500- versus 1000-ml tidal volumes during out-of-hospital CPR
Resuscitation, 45 (1), 27-33
DOI 10.1016/s0300-9572(00)00162-3, PubMed 10838236 -
Enhanced sarcoplasmic reticulum Ca(2+) release following intermittent sprint training
Am J Physiol Regul Integr Comp Physiol, 279 (1), R152-60
DOI 10.1152/ajpregu.2000.279.1.R152, PubMed 10896877 -
Acute serogroup A streptococcal shock: A porcine model
J Infect Dis, 182 (1), 133-41
DOI 10.1086/315692, PubMed 10882590 -
Aminoethyl-isothiourea, a nitric oxide synthase inhibitor and oxygen radical scavenger, improves survival and counteracts hemodynamic deterioration in a porcine model of streptococcal shock
Crit Care Med, 28 (8), 2697-706
DOI 10.1097/00003246-200008000-00003, PubMed 10966238 -
Systemic activation of coagulation and fibrynolysis in a porcine model of serogroup A streptococcal shock
Blood Coagul Fibrinolysis, 11 (5), 433-8
DOI 10.1097/00001721-200007000-00006, PubMed 10937804 -
Influence of mild hypothermia after hypoxia-ischemia on the pharmacokinetics of gentamicin in newborn pigs
Biol Neonate, 77 (1), 50-7
DOI 10.1159/000014195, PubMed 10658831 -
Dynamics and consequences of potassium shifts in skeletal muscle and heart during exercise
Physiol Rev, 80 (4), 1411-81
DOI 10.1152/physrev.2000.80.4.1411, PubMed 11015618 -
Effects on infarct size and on arrhythmias by controlling reflow after myocardial ischaemia in pigs
Acta Physiol Scand, 169 (3), 195-201
DOI 10.1046/j.1365-201x.2000.00735.x, PubMed 10886034 -
Echocardiographic criteria for detection of postinfarction congestive heart failure in rats
J Appl Physiol (1985), 89 (4), 1445-54
DOI 10.1152/jappl.2000.89.4.1445, PubMed 11007581 -
Importance of heart rate for acute hibernation in isolated blood-perfused piglet hearts
J Cardiovasc Surg (Torino), 41 (6), 807-17
PubMed 11232963 -
Adenosine and cardioprotection during ischaemia and reperfusion--an overview
Acta Anaesthesiol Scand, 44 (9), 1038-55
DOI 10.1034/j.1399-6576.2000.440903.x, PubMed 11028722 -
Nitric oxide indices in human septic shock
Crit Care Med, 28 (8), 2779-85
DOI 10.1097/00003246-200008000-00017, PubMed 10966250 -
Transmyocardial laser treatment reduces ischemia-induced ventricular fibrillation during the early phase (1a) after coronary artery occlusion in open chest anesthetized pigs
J Cardiovasc Surg (Torino), 41 (5), 675-82
PubMed 11149632 -
Cardiac endothelin-like immunoreactivity and preproendothelin-1 mRNA expression in human heart failure
Scand Cardiovasc J, 34 (1), 21-7
DOI 10.1080/14017430050142350, PubMed 10816056 -
Endotoxemia alters splanchnic capacitance
Shock, 14 (1), 68-72
DOI 10.1097/00024382-200014010-00012, PubMed 10909896 -
Altered E-C coupling in rat ventricular myocytes from failing hearts 6 wk after MI
Am J Physiol Heart Circ Physiol, 279 (2), H798-807
DOI 10.1152/ajpheart.2000.279.2.H798, PubMed 10924080 -
Automatic and manual mechanical external chest compression devices for cardiopulmonary resuscitation
Resuscitation, 47 (1), 7-25
DOI 10.1016/s0300-9572(00)00190-8, PubMed 11004377 -
CPR artifact removal from human ECG using optimal multichannel filtering
IEEE Trans Biomed Eng, 47 (11), 1440-9
DOI 10.1109/10.880095, PubMed 11077737