Geir Christensen

  • Professor emeritus; MD, PhD
  • +47 23016793
 

Publications 2022

Carlson CR, Aronsen JM, Bergan-Dahl A, Moutty MC, Lunde M, Lunde PK, Jarstadmarken H, Wanichawan P, Pereira L, Kolstad TRS, Dalhus B, Subramanian H, Hille S, Christensen G, Muller OJ, Nikolaev V, Bers DM, Sjaastad I, Shen X, Louch WE, Klussmann E, Sejersted OM (2022)
AKAP18 delta Anchors and Regulates CaMKII Activity at Phospholamban-SERCA2 and RYR
Circ.Res., 130 (1), 27-44
DOI 10.1161/CIRCRESAHA.120.317976

Lunde IG, Skrbic B, Sjaastad I, Christensen G, Carlson CR, Tønnessen T (2022)
Calcineurin-NFAT dynamics correspond to cardiac remodeling during aortic banding and debanding, mimicking aortic valve replacement
Front Mol Med, 2, 1-14
DOI 10.3389/fmmed.2022.980717, PublikaID 435

Publications 2021

Berge K, Lyngbakken MN, Myhre PL, Brynildsen J, Roysland R, Strand H, Christensen G, Hoiseth AD, Omland T, Rosjo H (2021)
High-sensitivity cardiac troponin T and N-terminal pro-B-type natriuretic peptide in acute heart failure: Data from the ACE 2 study
Clin. Biochem., 88, 30-36
DOI 10.1016/j.clinbiochem.2020.11.009

Myhre PL, Ottesen AH, Faaren AL, Tveit SH, Springett J, Pyylampi J, Stridsberg M, Christensen G, Hoiseth AD, Omland T, Rosjo H (2021)
Performance of a Novel Research-Use-Only Secretoneurin ELISA in Patients with Suspected Acute Coronary Syndrome: Comparison with an Established Secretoneurin Radioimmunoassay
Cardiology, 146 (5), 566-574
DOI 10.1159/000517444

Norden ES, Bendiksen BA, Andresen H, Bergo KK, Espe EK, Hasic A, Hauge-Iversen IM, Veras I, Hussain RI, Sjaastad I, Christensen G, Cataliotti A (2021)
Sacubitril/valsartan ameliorates cardiac hypertrophy and preserves diastolic function in cardiac pressure overload
ESC Heart Fail., 8 (2), 918-927
DOI 10.1002/ehf2.13177

Rutkovskiy A, Lyngbakken MN, Dahl MB, Bye A, Pedersen MH, Wisloff U, Christensen G, Hoiseth AD, Omland T, Rosjo H (2021)
Circulating MicroRNA-210 Concentrations in Patients with Acute Heart Failure: Data from the Akershus Cardiac Examination 2 Study
Clin. Chem., 67 (6), 889-898
DOI 10.1093/clinchem/hvab030

Rypdal KB, Erusappan PM, Melleby AO, Seifert DE, Palmero S, Strand ME, Tonnessen T, Dahl CP, Almaas V, Hubmacher D, Apte SS, Christensen G, Lunde IG (2021)
The extracellular matrix glycoprotein ADAMTSL2 is increased in heart failure and inhibits TGF beta signalling in cardiac fibroblasts
Sci Rep, 11 (1), 19757
DOI 10.1038/s41598-021-99032-2

Aakre KM, Ottesen AH, Strand H, Faaren AL, Alaour B, Torsvik J, Sylte MS, Marber M, Christensen G, Rosjo H, Omland T (2021)
Biological variation of secretoneurin; a novel cardiovascular biomarker implicated in arrhythmogenesis
Clin. Biochem., 98, 74-77
DOI 10.1016/j.clinbiochem.2021.09.014

Publications 2020

Herum KM, Romaine A, Wang A, Melleby AO, Strand ME, Pacheco J, Braathen B, Duner P, Tonnessen T, Lunde IG, Sjaastad I, Brakebusch C, McCulloch AD, Gomez MF, Carlson CR, Christensen G (2020)
Syndecan-4 Protects the Heart From the Profibrotic Effects of Thrombin-Cleaved Osteopontin
J. Am. Heart Assoc., 9 (3), e013518
DOI 10.1161/JAHA.119.013518

Mathiesen SB, Lunde M, Stensland M, Martinsen M, Nyman TA, Christensen G, Carlson CR (2020)
The Cardiac Syndecan-2 Interactome
Front. Cell. Dev. Biol., 8, 792
DOI 10.3389/fcell.2020.00792

Mohammadzadeh N, Melleby AO, Palmero S, Sjaastad I, Chakravarti S, Engebretsen KVT, Christensen G, Lunde IG, Tonnessen T (2020)
Moderate Loss of the Extracellular Matrix Proteoglycan Lumican Attenuates Cardiac Fibrosis in Mice Subjected to Pressure Overload
Cardiology, 145 (3), 187-198
DOI 10.1159/000505318

Ronning SB, Carlson CR, Aronsen JM, Pisconti A, Host V, Lunde M, Liland KH, Sjaastad I, Kolset SO, Christensen G, Pedersen ME (2020)
Syndecan-4(-/-)Mice Have Smaller Muscle Fibers, Increased Akt/mTOR/S6K1 and Notch/HES-1 Pathways, and Alterations in Extracellular Matrix Components
Front. Cell. Dev. Biol., 8, 730
DOI 10.3389/fcell.2020.00730

Publications 2019

Brynildsen J, Myhre PL, Lyngbakken MN, Klaeboe LG, Stridsberg M, Christensen G, Edvardsen T, Omland T, Rosjo H (2019)
Circulating secretoneurin concentrations in patients with moderate to severe aortic stenosis
Clin. Biochem., 71, 17-23
DOI 10.1016/j.clinbiochem.2019.06.008

Brynildsen J, Petaja L, Myhre PL, Lyngbakken MN, Nygard S, Stridsberg M, Christensen G, Ottesen AH, Pettila V, Omland T, Rosjo H (2019)
Circulating Secretoneurin Concentrations After Cardiac Surgery: Data From the FINNish Acute Kidney Injury Heart Study
Crit. Care Med., 47 (5), E412-E419
DOI 10.1097/CCM.0000000000003670

Christensen G, Herum KM, Lunde IG (2019)
Sweet, yet underappreciated: Proteoglycans and extracellular matrix remodeling in heart disease
Matrix Biol., 75-76, 286-299
DOI 10.1016/j.matbio.2018.01.001

Lipsett DB, Frisk M, Aronsen JM, Norden ES, Buonarati R, Cataliotti A, Hell JW, Sjaastad I, Christensen G, Louch WE (2019)
Cardiomyocyte substructure reverts to an immature phenotype during heart failure
J. Physiol.-London, 597 (7), 1833-1853
DOI 10.1113/JP277273

Mathiesen SB, Lunde M, Aronsen JM, Romaine A, Kaupang A, Martinsen M, de Souza GA, Nyman TA, Sjaastad I, Christensen G, Carlson CR (2019)
The cardiac syndecan-4 interactome reveals a role for syndecan-4 in nuclear translocation of muscle LIM protein (MLP)
J. Biol. Chem., 294 (22), 8717-8731
DOI 10.1074/jbc.RA118.006423

Mohammadzadeh N, Lunde IG, Andenaes K, Strand ME, Aronsen JM, Skrbic B, Marstein HS, Bandlien C, Nygard S, Gorham J, Sjaastad I, Chakravarti S, Christensen G, Engebretsen KVT, Tonnessen T (2019)
The extracellular matrix proteoglycan lumican improves survival and counteracts cardiac dilatation and failure in mice subjected to pressure overload
Sci Rep, 9, 9206
DOI 10.1038/s41598-019-45651-9

Ottesen AH, Carlson CR, Eken OS, Sadredini M, Myhre PL, Shen X, Dalhus B, Laver DR, Lunde PK, Kurola J, Lunde M, Hoff JE, Godang K, Sjaastad I, Pettila V, Stridsberg M, Lehnart SE, Edwards AG, Lunde IG, Omland T, Stokke MK, Christensen G, Rosjo H, Louch WE (2019)
Secretoneurin Is an Endogenous Calcium/Calmodulin-Dependent Protein Kinase II Inhibitor That Attenuates Ca2+-Dependent Arrhythmia
Circ.-Arrhythmia Electrophysiol., 12 (4), e007045
DOI 10.1161/CIRCEP.118.007045

Roe AT, Ruud M, Espe EK, Manfra O, Longobardi S, Aronsen JM, Norden ES, Husebye T, Kolstad TRS, Cataliotti A, Christensen G, Sejersted OM, Niederer SA, Andersen GO, Sjaastad I, Louch WE (2019)
Regional diastolic dysfunction in post-infarction heart failure: role of local mechanical load and SERCA expression
Cardiovasc. Res., 115 (4), 752-764
DOI 10.1093/cvr/cvy257

Udjus C, Cero FT, Halvorsen B, Behmen D, Carlson CR, Bendiksen BA, Espe EKS, Sjaastad I, Loberg EM, Yndestad A, Aukrust P, Christensen G, Skjonsberg OH, Larsen KO (2019)
Caspase-1 induces smooth muscle cell growth in hypoxia-induced pulmonary hypertension
Am. J. Physiol.-Lung Cell. Mol. Physiol., 316 (6), L999-L1012
DOI 10.1152/ajplung.00322.2018

Publications 2018

Andenaes K, Lunde IG, Mohammadzadeh N, Dahl CP, Aronsen JM, Strand ME, Palmero S, Sjaastad I, Christensen G, Engebretsen KVT, Tonnessen T (2018)
The extracellular matrix proteoglycan fibromodulin is upregulated in clinical and experimental heart failure and affects cardiac remodeling
PLoS One, 13 (7), e0201422
DOI 10.1371/journal.pone.0201422

Berge K, Lyngbakken MN, Einvik G, Winther JA, Brynildsen J, Roysland R, Strand H, Christensen G, Hoiseth AD, Omland T, Rosjo H (2018)
Diagnostic and prognostic properties of procalcitonin in patients with acute dyspnea: Data from the ACE 2 Study
Clin. Biochem., 59, 62-68
DOI 10.1016/j.clinbiochem.2018.07.006

Gamage TH, Gunnes G, Lee RH, Louch WE, Holmgren A, Bruton JD, Lengle E, Kolstad TRS, Revold T, Amundsen SS, Dalen KT, Holme PA, Tjonnfjord GE, Christensen G, Westerblad H, Klungland A, Bergmeier W, Misceo D, Frengen E (2018)
STIM1 R304W causes muscle degeneration and impaired platelet activation in mice
Cell Calcium, 76, 87-100
DOI 10.1016/j.ceca.2018.10.001

Lyngbakken MN, Pervez MO, Brynildsen J, Pedersen MH, Solvernes J, Christensen G, Hoiseth AD, Omland T, Rosjo H (2018)
Fibroblast growth factor 23 in patients with acute dyspnea: Data from the Akershus Cardiac Examination (ACE) 2 Study
Clin. Biochem., 52, 41-47
DOI 10.1016/j.clinbiochem.2017.10.015

Melleby AO, Romaine A, Aronsen JM, Veras I, Zhang LL, Sjaastad I, Lunde IG, Christensen G (2018)
A novel method for high precision aortic constriction that allows for generation of specific cardiac phenotypes in mice
Cardiovasc. Res., 114 (12), 1680-1690
DOI 10.1093/cvr/cvy141

Pervez MO, Winther JA, Brynildsen J, Strand H, Christensen G, Hoiseth AD, Myhre PL, Roysland R, Lyngbakken MN, Omland T, Rosjo H (2018)
Prognostic and diagnostic significance of mid-regional pro-atrial natriuretic peptide in acute exacerbation of chronic obstructive pulmonary disease and acute heart failure: data from the ACE 2 Study
Biomarkers, 23 (7), 654-663
DOI 10.1080/1354750X.2018.1474258

Romaine A, Sorensen IW, Zeltz C, Lu N, Erusappan PM, Melleby AO, Zhang L, Bendiksen B, Robinson EL, Aronsen JM, Herum KM, Danielsen HE, Sjaastad I, Christensen G, Gullberg D (2018)
Overexpression of integrin alpha 11 induces cardiac fibrosis in mice
Acta Physiol., 222 (2), e12932
DOI 10.1111/apha.12932

Rosjo H, Masson S, Caironi P, Stridsberg M, Magnoli M, Christensen G, Moise G, Urbano MC, Gattinoni L, Pesenti A, Latini R, Omland T, ALBIOS Biomarkers Study (2018)
Prognostic Value of Secretoneurin in Patients With Severe Sepsis and Septic Shock: Data From the Albumin Italian Outcome Sepsis Study
Crit. Care Med., 46 (5), E404-E410
DOI 10.1097/CCM.0000000000003050

Publications 2017

Abraityte A, Lunde IG, Askevold ET, Michelsen AE, Christensen G, Aukrust P, Yndestad A, Fiane A, Andreassen A, Aakhus S, Dahl CP, Gullestad L, Broch K, Ueland T (2017)
Wnt5a is associated with right ventricular dysfunction and adverse outcome in dilated cardiomyopathy
Sci Rep, 7, 3490
DOI 10.1038/s41598-017-03625-9

Abraityte A, Vinge LE, Askevold ET, Lekva T, Michelsen AE, Ranheim T, Alfsnes K, Fiane A, Aakhus S, Lunde IG, Dahl CP, Aukrust P, Christensen G, Gullestad L, Yndestad A, Ueland T (2017)
Wnt5a is elevated in heart failure and affects cardiac fibroblast function
J. Mol. Med., 95 (7), 767-777
DOI 10.1007/s00109-017-1529-1

Dhondup Y, Sjaastad I, Sandanger O, Aronsen JM, Ahmed MS, Attramadal H, Finsen AV, Zhang LL, Ranheim T, Alfsnes K, Aukrust P, Christensen G, Yndestad A, Vinge LE (2017)
Toll-Like Receptor 9 Promotes Survival in SERCA2a KO Heart Failure Mice
Mediat. Inflamm., 2017, 9450439
DOI 10.1155/2017/9450439

Herum KM, Lunde IG, McCulloch AD, Christensen G (2017)
The Soft-and Hard-Heartedness of Cardiac Fibroblasts: Mechanotransduction Signaling Pathways in Fibrosis of the Heart
J. Clin. Med., 6 (5), 53
DOI 10.3390/jcm6050053

Myhre PL, Stridsberg M, Linko R, Okkonen M, Nygard S, Christensen G, Pettila V, Omland T, Rosjo H, FINNALI Study Grp (2017)
Circulating chromogranin B levels in patients with acute respiratory failure: data from the FINNALI Study
Biomarkers, 22 (8), 775-781
DOI 10.1080/1354750X.2016.1269200

Norum HM, Broch K, Michelsen AE, Lunde IG, Lekva T, Abraityte A, Dahl CP, Fiane AE, Andreassen AK, Christensen G, Aakhus S, Aukrust P, Gullestad L, Ueland T (2017)
The Notch Ligands DLL1 and Periostin Are Associated with Symptom Severity and Diastolic Function in Dilated Cardiomyopathy
J. Cardiovasc. Transl. Res., 10 (4), 401-410
DOI 10.1007/s12265-017-9748-y

Olsen MB, Hildrestrand GA, Scheffler K, Vinge LE, Alfsnes K, Palibrk V, Wang JB, Neurauter CG, Luna L, Johansen J, Ogaard JDS, Ohm IK, Slupphaug G, Kusnierczyk A, Fiane AE, Brorson SH, Zhang LL, Gullestad L, Louch WE, Iversen PO, Ostlie I, Klungland A, Christensen G, Sjaastad I, Saetrom P et al. (2017)
NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture
Cell Reports, 18 (1), 82-92
DOI 10.1016/j.celrep.2016.12.009

Ottesen AH, Carlson CR, Louch WE, Dahl MB, Sandbu RA, Johansen RF, Jarstadmarken H, Bjoras M, Hoiseth AD, Brynildsen J, Sjaastad I, Stridsberg M, Omland T, Christensen G, Rosjo H (2017)
Glycosylated Chromogranin A in Heart Failure Implications for Processing and Cardiomyocyte Calcium Homeostasis
Circ.-Heart Fail., 10 (2)
DOI 10.1161/CIRCHEARTFAILURE.116.003675

Pervez MO, Lyngbakken MN, Myhre PL, Brynildsen J, Langsjoen EC, Hoiseth AD, Christensen G, Omland T, Rosjo H (2017)
Mid-regional pro-adrenomedullin in patients with acute dyspnea: Data from the Akershus Cardiac Examination (ACE) 2 Study
Clin. Biochem., 50 (7-8), 394-400
DOI 10.1016/j.clinbiochem.2016.12.010

Winther JA, Brynildsen J, Hoiseth AD, Strand H, Folling I, Christensen G, Nygard S, Rosjo H, Omland T (2017)
Prognostic and diagnostic significance of copeptin in acute exacerbation of chronic obstructive pulmonary disease and acute heart failure: data from the ACE 2 study
Respir. Res., 18, 184
DOI 10.1186/s12931-017-0665-z

Publications 2016

Evenset A, Hallanger IG, Tessmann M, Warner N, Ruus A, Borga K, Gabrielsen GW, Christensen G, Renaud PE (2016)
Seasonal variation in accumulation of persistent organic pollutants in an Arctic marine benthic food web
Sci. Total Environ., 542, 108-120
DOI 10.1016/j.scitotenv.2015.10.092

Hoiseth AD, Brynildsen J, Hagve TA, Christensen G, Soyseth V, Torbjorn O, Rosjo H (2016)
The influence of heart failure co-morbidity on high-sensitivity troponin T levels in COPD exacerbation in a prospective cohort study: data from the Akershus cardiac examination (ACE) 2 study
Biomarkers, 21 (2), 173-179
DOI 10.3109/1354750X.2015.1126645

Lunde IG, Herum KM, Carlson CC, Christensen G (2016)
Syndecans in heart fibrosis
Cell Tissue Res., 365 (3), 539-552
DOI 10.1007/s00441-016-2454-2

Melleby AO, Strand ME, Romaine A, Herum KM, Skrbic B, Dahl CP, Sjaastad I, Fiane AE, Filmus J, Christensen G, Lunde IG (2016)
The Heparan Sulfate Proteoglycan Glypican-6 Is Upregulated in the Failing Heart, and Regulates Cardiomyocyte Growth through ERK1/2 Signaling
PLoS One, 11 (10), e0165079
DOI 10.1371/journal.pone.0165079

Myhre PL, Ottesen AH, Okkonen M, Linko R, Stridsberg M, Nygard S, Christensen G, Pettila V, Omland T, Rosjo H, FINNALI Lab Study Grp (2016)
Prognostic Value of Secretoneurin in Patients with Acute Respiratory Failure: Data from the FINNALI Study
Clin. Chem., 62 (10), 1380-1389
DOI 10.1373/clinchem.2016.258764

Rosjo H, Stridsberg M, Ottesen AH, Nygard S, Christensen G, Pettila V, Linko R, Karlsson S, Varpula T, Ruokonen E, Omland T, FINNSEPSIS Study Grp FINNALI Study Grp (2016)
Prognostic Value of Secretoneurin in Critically III Patients With Infections
Crit. Care Med., 44 (10), 1882-1890
DOI 10.1097/CCM.0000000000001832

Winther JA, Brynildsen J, Hoiseth AD, Folling I, Brekke PH, Christensen G, Hagve TA, Verbalis JG, Omland T, Rosjo H (2016)
Prevalence and Prognostic Significance of Hyponatremia in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Data from the Akershus Cardiac Examination (ACE) 2 Study
PLoS One, 11 (8), e0161232
DOI 10.1371/journal.pone.0161232

Publications 2015

Brynildsen J, Hoiseth AD, Nygard S, Hagve TA, Christensen G, Omland T, Rosjo H (2015)
Diagnostic accuracy for heart failure- data from Akershus heart survey 2
Tidsskr. Nor. Laegeforen., 135 (19), 1738-1744
DOI 10.4045/tidsskr.14.1174

Bytingsvik J, Frantzen M, Gotsch A, Heimstad ES, Christensen G, Evenset A (2015)
Current status, between-year comparisons and maternal transfer of organohalogenated compounds (OHCs) in Arctic char (Salvelinus alpinus) from Bjornoya, Svalbard (Norway)
Sci. Total Environ., 521, 421-430
DOI 10.1016/j.scitotenv.2015.03.104

Cero FT, Hillestad V, Sjaastad I, Yndestad A, Aukrust P, Ranheim T, Lunde IG, Olsen MB, Lien E, Zhang LL, Haugstad SB, Loberg EM, Christensen G, Larsen KO, Skjonsberg OH (2015)
Absence of the inflammasome adaptor ASC reduces hypoxia-induced pulmonary hypertension in mice
Am. J. Physiol.-Lung Cell. Mol. Physiol., 309 (4), L378-L387
DOI 10.1152/ajplung.00342.2014

Dhondup Y, Sjaastad I, Scott H, Sandanger O, Zhang LL, Haugstad SB, Aronsen JM, Ranheim T, Holmen SD, Alfsnes K, Ahmed MS, Attramadal H, Gullestad L, Aukrust P, Christensen G, Yndestad A, Vinge LE (2015)
Sustained Toll-Like Receptor 9 Activation Promotes Systemic and Cardiac Inflammation, and Aggravates Diastolic Heart Failure in SERCA2a KO Mice
PLoS One, 10 (10), e0139715
DOI 10.1371/journal.pone.0139715

Einvik G, Dammen T, Hoiseth AD, Brynildsen J, Hagve TA, Christensen G, Omland T, Rosjo H (2015)
Psychological distress and mortality in patients with acute dyspnea: data from the Akershus Cardiac Examination (ACE) 2 Study
Gen. Hosp. Psych., 37 (6), 548-553
DOI 10.1016/j.genhosppsych.2015.07.007

Herum KM, Lunde IG, Skrbic B, Louch WE, Hasic A, Boye S, Unger A, Brorson SH, Sjaastad I, Tonnessen T, Linke WA, Gomez MF, Christensen G (2015)
Syndecan-4 is a key determinant of collagen cross-linking and passive myocardial stiffness in the pressure-overloaded heart
Cardiovasc. Res., 106 (2), 217-226
DOI 10.1093/cvr/cvv002

Hillestad V, Espe EKS, Cero F, Larsen KO, Sjaastad I, Nygard S, Skjonsberg OH, Christensen G (2015)
IL-18 neutralization during alveolar hypoxia improves left ventricular diastolic function in mice
Acta Physiol., 213 (2), 492-504
DOI 10.1111/apha.12376

Kho C, Lee A, Jeong D, Oh JG, Gorski PA, Fish K, Sanchez R, DeVita RJ, Christensen G, Dahl R, Hajjar RJ (2015)
Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure
Nat. Commun., 6, 7229
DOI 10.1038/ncomms8229

Majak P, Lunde IG, Hasic AK, Husebye T, Christensen G, Tonnessen T, Bjornstad JL (2015)
Reduced visfatin levels in aortic stenosis increase after aortic valve replacement and may contribute to reverse left ventricular remodelling
J. Cardiovasc. Surg., 56 (3), 483-492

Ottesen AH, Louch WE, Carlson CR, Landsverk OJB, Kurola J, Johansen RF, Moe MK, Aronsen JM, Hoiseth AD, Jarstadmarken H, Nygard S, Bjoras M, Sjaastad I, Pettila V, Stridsberg M, Omland T, Christensen G, Rosjo H (2015)
Secretoneurin Is a Novel Prognostic Cardiovascular Biomarker Associated With Cardiomyocyte Calcium Handling
J. Am. Coll. Cardiol., 65 (4), 339-351
DOI 10.1016/j.jacc.2014.10.065

Rosjo H, Dahl MB, Jorgensen M, Roysland R, Brynildsen J, Cataliotti A, Christensen G, Hoiseth AD, Hagve TA, Omland T (2015)
Influence of Glycosylation on Diagnostic and Prognostic Accuracy of N-Terminal Pro-B-Type Natriuretic Peptide in Acute Dyspnea: Data from the Akershus Cardiac Examination 2 Study
Clin. Chem., 61 (8), 1087-1097
DOI 10.1373/clinchem.2015.239673

Skrbic B, Engebretsen KVT, Strand ME, Lunde IG, Herum KM, Marstein HS, Sjaastad I, Lunde PK, Carlson CR, Christensen G, Bjornstad JL, Tonnessen T (2015)
Lack of collagen VIII reduces fibrosis and promotes early mortality and cardiac dilatation in pressure overload in mice
Cardiovasc. Res., 106 (1), 32-42
DOI 10.1093/cvr/cvv041

Strand ME, Aronsen JM, Braathen B, Sjaastad I, Kvaloy H, Tonnessen T, Christensen G, Lunde IG (2015)
Shedding of syndecan-4 promotes immune cell recruitment and mitigates cardiac dysfunction after lipopolysaccharide challenge in mice
J. Mol. Cell. Cardiol., 88, 133-144
DOI 10.1016/j.yjmcc.2015.10.003

Ytrehus K, Larsen T, Christensen G, Stenslokken KO, Levy FO (2015)
In memory of Guro Valen (1960-2014)
J. Mol. Cell. Cardiol., 79, 254-255
DOI 10.1016/j.yjmcc.2014.11.026

Publications 2014

Askevold ET, Aukrust P, Nymo SH, Lunde IG, Kaasboll OJ, Aakhus S, Florholmen G, Ohm IK, Strand ME, Attramadal H, Fiane A, Dahl CP, Finsen AV, Vinge LE, Christensen G, Yndestad A, Gullestad L, Latini R, Masson S, Tavazzi L, Ueland T, GISSI-HF Investigators (2014)
The cardiokine secreted Frizzled-related protein 3, a modulator of Wnt signalling, in clinical and experimental heart failure
J. Intern. Med., 275 (6), 621-630
DOI 10.1111/joim.12175

Boardman NT, Aronsen JM, Louch WE, Sjaastad I, Willoch F, Christensen G, Sejersted O, Aasum E (2014)
Impaired left ventricular mechanical and energetic function in mice after cardiomyocyte-specific excision of Serca2
Am. J. Physiol.-Heart Circul. Physiol., 306 (7), H1018-H1024
DOI 10.1152/ajpheart.00741.2013

Engebretsen KVT, Skardal K, Bjornstad S, Marstein HS, Skrbic B, Sjaastad I, Christensen G, Bjornstad JL, Tonnessen T (2014)
Attenuated development of cardiac fibrosis in left ventricular pressure overload by SM16, an orally active inhibitor of ALK5
J. Mol. Cell. Cardiol., 76, 148-157
DOI 10.1016/j.yjmcc.2014.08.008

Finsen AV, Ueland T, Sjaastad I, Ranheim T, Ahmed MS, Dahl CP, Askevold ET, Aakhus S, Husberg C, Fiane AE, Lipp M, Gullestad L, Christensen G, Aukrust P, Yndestad A (2014)
The Homeostatic Chemokine CCL21 Predicts Mortality in Aortic Stenosis Patients and Modulates Left Ventricular Remodeling
PLoS One, 9 (11), e112172
DOI 10.1371/journal.pone.0112172

Misceo D, Holmgren A, Louch WE, Holme PA, Mizobuchi M, Morales RJ, De Paula AM, Stray-Pedersen A, Lyle R, Dalhus B, Christensen G, Stormorken H, Tjonnfjord GE, Frengen E (2014)
A Dominant STIM1 Mutation Causes Stormorken Syndrome
Hum. Mutat., 35 (5), 556-564
DOI 10.1002/humu.22544

Nygard S, Reitan T, Clancy T, Nygaard V, Bjornstad J, Skrbic B, Tonnessen T, Christensen G, Hovig E (2014)
Identifying pathogenic processes by integrating microarray data with prior knowledge
BMC Bioinformatics, 15, 115
DOI 10.1186/1471-2105-15-115

Rosjo H, Dahl MB, Bye A, Andreassen J, Jorgensen M, Wisloff U, Christensen G, Edvardsen T, Omland T (2014)
Prognostic Value of Circulating MicroRNA-210 Levels in Patients with Moderate to Severe Aortic Stenosis
PLoS One, 9 (3), e91812
DOI 10.1371/journal.pone.0091812

Sanner H, Schwartz T, Flato B, Vistnes M, Christensen G, Sjaastad I (2014)
Increased Levels of Eotaxin and MCP-1 in Juvenile Dermatomyositis Median 16.8 Years after Disease Onset; Associations with Disease Activity, Duration and Organ Damage
PLoS One, 9 (3), e92171
DOI 10.1371/journal.pone.0092171

Schwartz T, Sjaastad I, Flato B, Vistnes M, Christensen G, Sanner H (2014)
In active juvenile dermatomyositis, elevated eotaxin and MCP-1 and cholesterol levels in the upper normal range are associated with cardiac dysfunction
RHEUMATOLOGY, 53 (12), 2214-2222
DOI 10.1093/rheumatology/keu256

Vistnes M, Aronsen JM, Lunde IG, Sjaastad I, Carlson CR, Christensen G (2014)
Pentosan Polysulfate Decreases Myocardial Expression of the Extracellular Matrix Enzyme ADAMTS4 and Improves Cardiac Function In Vivo in Rats Subjected to Pressure Overload by Aortic Banding
PLoS One, 9 (3), e89621
DOI 10.1371/journal.pone.0089621

Publications 2013

Engebretsen KVT, Lunde IG, Strand ME, Waehre A, Sjaastad I, Marstein HS, Skrbic B, Dahl CP, Askevold ET, Christensen G, Bjornstad JL, Tonnessen T (2013)
Lumican is increased in experimental and clinical heart failure, and its production by cardiac fibroblasts is induced by mechanical and proinflammatory stimuli
FEBS J., 280 (10), 2382-2398
DOI 10.1111/febs.12235

Engebretsen KVT, Waehre A, Bjornstad JL, Skrbic B, Sjaastad I, Behmen D, Marstein HS, Yndestad A, Aukrust P, Christensen G, Tonnessen T (2013)
Decorin, lumican, and their GAG chain-synthesizing enzymes are regulated in myocardial remodeling and reverse remodeling in the mouse
J. Appl. Physiol., 114 (8), 988-997
DOI 10.1152/japplphysiol.00793.2012

Heinis FI, Andersson KB, Christensen G, Metzger JM (2013)
Prominent Heart Organ-Level Performance Deficits in a Genetic Model of Targeted Severe and Progressive SERCA2 Deficiency
PLoS One, 8 (11), e79609
DOI 10.1371/journal.pone.0079609

Herum KM, Lunde IG, Skrbic B, Florholmen G, Behmen D, Sjaastad I, Carlson CR, Gomez MF, Christensen G (2013)
Syndecan-4 signaling via NFAT regulates extracellular matrix production and cardiac myofibroblast differentiation in response to mechanical stress
J. Mol. Cell. Cardiol., 54, 73-81
DOI 10.1016/j.yjmcc.2012.11.006

Hillestad V, Kramer F, Golz S, Knorr A, Andersson KB, Christensen G (2013)
Long-term levosimendan treatment improves systolic function and myocardial relaxation in mice with cardiomyocyte-specific disruption of the Serca2 gene
J. Appl. Physiol., 115 (10), 1572-1580
DOI 10.1152/japplphysiol.01044.2012

Moltzau LR, Aronsen JM, Meier S, Nguyen CHT, Hougen K, Orstavik O, Sjaastad I, Christensen G, Skomedal T, Osnes JB, Levy FO, Qvigstad E (2013)
SERCA2 activity is involved in the CNP-mediated functional responses in failing rat myocardium
Br. J. Pharmacol., 170 (2), 366-379
DOI 10.1111/bph.12282

Oyehaug L, Loose KO, Jolle GF, Roe AT, Sjaastad I, Christensen G, Sejersted OM, Louch WE (2013)
Synchrony of Cardiomyocyte Ca2+ Release is Controlled by t-tubule Organization, SR Ca2+ Content, and Ryanodine Receptor Ca2+ Sensitivity
Biophys. J., 104 (8), 1685-1697
DOI 10.1016/j.bpj.2013.03.022

Rosjo H, Opstad PK, Hoff JE, Godang K, Christensen G, Stridsberg M, Omland T (2013)
Effect of short- and long-term physical activities on circulating granin protein levels
Regul. Pept., 185, 14-19
DOI 10.1016/j.regpep.2013.06.003

Sandanger O, Ranheim T, Vinge LE, Bliksoen M, Alfsnes K, Finsen AV, Dahl CP, Askevold ET, Florholmen G, Christensen G, Fitzgerald KA, Lien E, Valen G, Espevik T, Aukrust P, Yndestad A (2013)
The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemiareperfusion injury
Cardiovasc. Res., 99 (1), 164-174
DOI 10.1093/cvr/cvt091

Skrbic B, Bjornstad JL, Marstein HS, Carlson CR, Sjaastad I, Nygard S, Bjornstad S, Christensen G, Tonnessen T (2013)
Differential regulation of extracellular matrix constituents in myocardial remodeling with and without heart failure following pressure overload
Matrix Biol., 32 (2), 133-142
DOI 10.1016/j.matbio.2012.11.011

Strand ME, Herum KM, Rana ZA, Skrbic B, Askevold ET, Dahl CP, Vistnes M, Hasic A, Kvaloy H, Sjaastad I, Carlson CR, Tonnessen T, Gullestad L, Christensen G, Lunde IG (2013)
Innate immune signaling induces expression and shedding of the heparan sulfate proteoglycan syndecan-4 in cardiac fibroblasts and myocytes, affecting inflammation in the pressure-overloaded heart
FEBS J., 280 (10), 2228-2247
DOI 10.1111/febs.12161

Vistnes M, Hoiseth AD, Rosjo H, Nygard S, Pettersen E, Soyseth V, Hurlen P, Christensen G, Omland T (2013)
Lack of pro-inflammatory cytokine mobilization predicts poor prognosis in patients with acute heart failure
Cytokine, 61 (3), 962-969
DOI 10.1016/j.cyto.2013.01.006

Publications 2012

Bjornstad JL, Skrbic B, Marstein HS, Hasic A, Sjaastad I, Louch WE, Florholmen G, Christensen G, Tonnessen T (2012)
Inhibition of SMAD2 phosphorylation preserves cardiac function during pressure overload
Cardiovasc. Res., 93 (1), 100-110
DOI 10.1093/cvr/cvr294

Bjornstad JL, Skrbic B, Sjaastad I, Bjornstad S, Christensen G, Tonnessen T (2012)
A mouse model of reverse cardiac remodelling following banding-debanding of the ascending aorta
Acta Physiol., 205 (1), 92-102
DOI 10.1111/j.1748-1716.2011.02369.x

Cero FT, Hillestad V, Loberg EM, Christensen G, Larsen KO, Skjonsberg OH (2012)
IL-18 and IL-12 synergy induces matrix degrading enzymes in the lung
Exp. Lung Res., 38 (8), 406-419
DOI 10.3109/01902148.2012.716903

Husberg C, Agnetti G, Holewinski RJ, Christensen G, Van Eyk JE (2012)
Dephosphorylation of cardiac proteins in vitro - a matter of phosphatase specificity
Proteomics, 12 (7), 973-978
DOI 10.1002/pmic.201100116

Li LR, Louch WE, Niederer SA, Aronsen JM, Christensen G, Sejersted OM, Smith NP (2012)
Sodium Accumulation in SERCA Knockout-Induced Heart Failure
Biophys. J., 102 (9), 2039-2048
DOI 10.1016/j.bpj.2012.03.045

Louch WE, Stokke MK, Sjaastad I, Christensen G, Sejersted OM (2012)
No Rest for the Weary: Diastolic Calcium Homeostasis in the Normal and Failing Myocardium
Physiology, 27 (5), 308-323
DOI 10.1152/physiol.00021.2012

Lunde IG, Aronsen JM, Kvaloy H, Qvigstad E, Sjaastad I, Tonnessen T, Christensen G, Gronning-Wang LM, Carlson CR (2012)
Cardiac O-GlcNAc signaling is increased in hypertrophy and heart failure
Physiol. Genomics, 44 (2), 162-172
DOI 10.1152/physiolgenomics.00016.2011

Majak P, Bjornstad JL, Braathen B, Lunde IG, Husebye T, Christensen G, Tonnessen T (2012)
Endothelin-1 in the Human Myocardium and Circulating Plasma: Evaluation before, during and after Correction of Aortic Stenosis with Aortic Valve Replacement
Cardiology, 123 (1), 1-10
DOI 10.1159/000339756

Rosjo H, Stridsberg M, Florholmen G, Stenslokken KO, Ottesen AH, Sjaastad I, Husberg C, Dahl MB, Oie E, Louch WE, Omland T, Christensen G (2012)
Secretogranin II; a Protein Increased in the Myocardium and Circulation in Heart Failure with Cardioprotective Properties
PLoS One, 7 (5), e37401
DOI 10.1371/journal.pone.0037401

Swift F, Christensen G (2012)
Calcium release units in heart failure: that's about the size of it
Cardiovasc. Res., 95 (4), 397-398
DOI 10.1093/cvr/cvs241

Swift F, Franzini-Armstrong C, Oyehaug L, Enger UH, Andersson KB, Christensen G, Sejersted OM, Louch WE (2012)
Extreme sarcoplasmic reticulum volume loss and compensatory T-tubule remodeling after Serca2 knockout
Proc. Natl. Acad. Sci. U. S. A., 109 (10), 3997-4001
DOI 10.1073/pnas.1120172109

Waehre A, Vistnes M, Sjaastad I, Nygard S, Husberg C, Lunde IG, Aukrust P, Yndestad A, Vinge LE, Behmen D, Neukamm C, Brun H, Thaulow E, Christensen G (2012)
Chemokines regulate small leucine-rich proteoglycans in the extracellular matrix of the pressure-overloaded right ventricle
J. Appl. Physiol., 112 (8), 1372-1382
DOI 10.1152/japplphysiol.01350.2011

Yndestad A, Finsen AV, Ueland T, Husberg C, Dahl CP, Oie E, Vinge LE, Sjaastad I, Sandanger O, Ranheim T, Dickstein K, Kjekshus J, Damas JK, Fiane AE, Hilfiker-Kleiner D, Lipp M, Gullestad L, Christensen G, Aukrust P (2012)
The Homeostatic Chemokine CCL21 Predicts Mortality and May Play a Pathogenic Role in Heart Failure
PLoS One, 7 (3), e33038
DOI 10.1371/journal.pone.0033038

Publications 2011

Bjornstad JL, Sjaastad I, Nygard S, Hasic A, Ahmed MS, Attramadal H, Finsen AV, Christensen G, Tonnessen T (2011)
Collagen isoform shift during the early phase of reverse left ventricular remodelling after relief of pressure overload
Eur. Heart J., 32 (2), 236-245
DOI 10.1093/eurheartj/ehq166

Finsen AV, Lunde IG, Sjaastad I, Ostli EK, Lyngra M, Jarstadmarken HO, Hasic A, Nygard S, Wilcox-Adelman SA, Goetinck PF, Lyberg T, Skrbic B, Florholmen G, Tonnessen T, Louch WE, Djurovic S, Carlson CR, Christensen G (2011)
Syndecan-4 Is Essential for Development of Concentric Myocardial Hypertrophy via Stretch-Induced Activation of the Calcineurin-NFAT Pathway
PLoS One, 6 (12), e28302
DOI 10.1371/journal.pone.0028302

Johansen IB, Lunde IG, Rosjo H, Christensen G, Nilsson GE, Bakken M, Overli O (2011)
Cortisol response to stress is associated with myocardial remodeling in salmonid fishes
J. Exp. Biol., 214 (8), 1313-1321
DOI 10.1242/jeb.053058

Larsen KO, Yndestad A, Sjaastad I, Loberg EM, Goverud IL, Halvorsen B, Jia J, Andreassen AK, Husberg C, Jonasson S, Lipp M, Christensen G, Aukrust P, Skjonsberg OH (2011)
Lack of CCR7 induces pulmonary hypertension involving perivascular leukocyte infiltration and inflammation
Am. J. Physiol.-Lung Cell. Mol. Physiol., 301 (1), L50-L59
DOI 10.1152/ajplung.00048.2010

Li L, Louch WE, Niederer SA, Andersson KB, Christensen G, Sejersted OM, Smith NP (2011)
Calcium Dynamics in the Ventricular Myocytes of SERCA2 Knockout Mice: A Modeling Study
Biophys. J., 100 (2), 322-331
DOI 10.1016/j.bpj.2010.11.048

Liu XH, Zhang ZY, Andersson KB, Husberg C, Enger UH, Raeder MG, Christensen G, Louch WE (2011)
Cardiomyocyte-specific disruption of Serca2 in adult mice causes sarco(endo)plasmic reticulum stress and apoptosis
Cell Calcium, 49 (4), 201-207
DOI 10.1016/j.ceca.2010.09.009

Lunde IG, Kvaloy H, Austbo B, Christensen G, Carlson CR (2011)
Angiotensin II and norepinephrine activate specific calcineurin-dependent NFAT transcription factor isoforms in cardiomyocytes
J. Appl. Physiol., 111 (5), 1278-1289
DOI 10.1152/japplphysiol.01383.2010

Sjaland C, Lunde PK, Swift F, Munkvik M, Ericsson M, Lunde M, Boye S, Christensen G, Ellingsen O, Sejersted OM, Andersson KB (2011)
Slowed relaxation and preserved maximal force in soleus muscles of mice with targeted disruption of the Serca2 gene in skeletal muscle
J. Physiol.-London, 589 (24), 6139-6155
DOI 10.1113/jphysiol.2011.211987

Stokke MK, Briston SJ, Jolle GF, Manzoor I, Louch WE, Oyehaug L, Christensen G, Eisner DA, Trafford AW, Sejersted OM, Sjaastad I (2011)
Ca2+ wave probability is determined by the balance between SERCA2-dependent Ca2+ reuptake and threshold SR Ca2+ content
Cardiovasc. Res., 90 (3), 503-512
DOI 10.1093/cvr/cvr013

Waehre A, Halvorsen B, Yndestad A, Husberg C, Sjaastad I, Nygard S, Dahl CP, Ahmed MS, Finsen AV, Reims H, Louch WE, Hilfiker-Kleiner D, Vinge LE, Roald B, Attramadal H, Lipp M, Gullestad L, Aukrust P, Christensen G (2011)
Lack of Chemokine Signaling through CXCR5 Causes Increased Mortality, Ventricular Dilatation and Deranged Matrix during Cardiac Pressure Overload
PLoS One, 6 (4), e18668
DOI 10.1371/journal.pone.0018668

Publications 2010

Ericsson M, Andersson KB, Amundsen BH, Torp SH, Sjaastad I, Christensen G, Sejersted OM, Ellingsen O (2010)
High-intensity exercise training in mice with cardiomyocyte-specific disruption of Serca2
J. Appl. Physiol., 108 (5), 1311-1320
DOI 10.1152/japplphysiol.01133.2009

Ericsson M, Sjaland C, Andersson KB, Sjaastad I, Christensen G, Sejersted OM, Ellingsen O (2010)
Exercise training before cardiac-specific Serca2 disruption attenuates the decline in cardiac function in mice
J. Appl. Physiol., 109 (6), 1749-1755
DOI 10.1152/japplphysiol.00282.2010

Hougen K, Aronsen JM, Stokke MK, Enger U, Nygard S, Andersson KB, Christensen G, Sejersted OM, Sjaastad I (2010)
Cre-loxP DNA recombination is possible with only minimal unspecific transcriptional changes and without cardiomyopathy in Tg(alpha MHC-MerCreMer) mice
Am. J. Physiol.-Heart Circul. Physiol., 299 (5), H1671-H1678
DOI 10.1152/ajpheart.01155.2009

Iversen PO, Andersson KB, Finsen AV, Sjaastad I, von Lueder TG, Sejersted OM, Attramadal H, Christensen G (2010)
Separate mechanisms cause anemia in ischemic vs. nonischemic murine heart failure
Am. J. Physiol.-Regul. Integr. Comp. Physiol., 298 (3), R808-R814
DOI 10.1152/ajpregu.00250.2009

Louch WE, Hougen K, Mork HK, Swift F, Aronsen JM, Sjaastad I, Reims HM, Roald B, Andersson KB, Christensen G, Sejersted OM (2010)
Sodium accumulation promotes diastolic dysfunction in end-stage heart failure following Serca2 knockout
J. Physiol.-London, 588 (3), 465-478
DOI 10.1113/jphysiol.2009.183517

Majak P, Bjornstad J, Vengen OA, Neverdal NO, Husebye T, Woldbaek P, Pepper J, Lie M, Christensen G, Tonnessen T (2010)
Plasma IL-18 and IL-18BP are altered differently in reverse remodeling following aortic valve replacement
Scand. Cardiovasc. J., 44 (2), 113-118
DOI 10.3109/14017430903426902

Rosjo H, Husberg C, Dahl MB, Stridsberg M, Sjaastad I, Finsen AV, Carlson CR, Oie E, Omland T, Christensen G (2010)
Chromogranin B in Heart Failure A Putative Cardiac Biomarker Expressed in the Failing Myocardium
Circ.-Heart Fail., 3 (4), 503-U84
DOI 10.1161/CIRCHEARTFAILURE.109.867747

Stokke MK, Hougen K, Sjaastad I, Louch WE, Briston SJ, Enger UH, Andersson KB, Christensen G, Eisner DA, Sejersted OM, Trafford AW (2010)
Reduced SERCA2 abundance decreases the propensity for Ca2+ wave development in ventricular myocytes
Cardiovasc. Res., 86 (1), 63-71
DOI 10.1093/cvr/cvp401

Vistnes M, Christensen G, Omland T (2010)
Multiple cytokine biomarkers in heart failure
Expert Rev. Mol. Diagn., 10 (2), 147-157
DOI 10.1586/ERM.10.3

Vistnes M, Waehre A, Nygard S, Sjaastad I, Andersson KB, Husberg C, Christensen G (2010)
Circulating cytokine levels in mice with heart failure are etiology dependent
J. Appl. Physiol., 108 (5), 1357-1364
DOI 10.1152/japplphysiol.01084.2009

Publications 2009

Andersson KB, Birkeland JAK, Finsen AV, Louch WE, Sjaastad I, Wang YB, Chen J, Molkentin JD, Chien KR, Sejersted OM, Christensen G (2009)
Moderate heart dysfunction in mice with inducible cardiomyocyte-specific excision of the Serca2 gene
J. Mol. Cell. Cardiol., 47 (2), 180-187
DOI 10.1016/j.yjmcc.2009.03.013

Andersson KB, Finsen AV, Sjaland C, Winer LH, Sjaastad I, Odegaard A, Louch WE, Wang YB, Chen J, Chien KR, Sejersted OM, Christensen G (2009)
Mice carrying a conditional Serca2(flox) allele for the generation of Ca2+ handling-deficient mouse models
Cell Calcium, 46 (3), 219-225
DOI 10.1016/j.ceca.2009.07.004

Dahl CP, Husberg C, Gullestad L, Waehre A, Damas JK, Vinge LE, Finsen AV, Ueland T, Florholmen G, Aakhus S, Halvorsen B, Aukrust P, Oie E, Yndestad A, Christensen G (2009)
Increased Production of CXCL16 in Experimental and Clinical Heart Failure A Possible Role in Extracellular Matrix Remodeling
Circ.-Heart Fail., 2 (6), 624-632
DOI 10.1161/CIRCHEARTFAILURE.108.821074

Madsen LH, Lund T, Grieg Z, Nygaard S, Holmvang L, Jurlander B, Grande P, Christensen G, Atar D (2009)
Cardiac Troponin I Degradation in Serum of Patients with Hypertrophic Obstructive Cardiomyopathy Undergoing Percutaneous Septal Ablation
Cardiology, 114 (3), 167-173
DOI 10.1159/000226596

Yndestad A, Landro L, Ueland T, Dahl CP, Flo TH, Vinge LE, Espevik T, Froland SS, Husberg C, Christensen G, Dickstein K, Kjekshus J, Oie E, Gullestad L, Aukrust P (2009)
Increased systemic and myocardial expression of neutrophil gelatinase-associated lipocalin in clinical and experimental heart failure
Eur. Heart J., 30 (10), 1229-1236
DOI 10.1093/eurheartj/ehp088

Yndestad A, Larsen KO, Oie E, Ueland T, Smith C, Halvorsen B, Sjaastad I, Skjonsberg OH, Pedersen TM, Anfinsen OG, Damas JK, Christensen G, Aukrust P, Andreassen AK (2009)
Elevated levels of activin A in clinical and experimental pulmonary hypertension
J. Appl. Physiol., 106 (4), 1356-1364
DOI 10.1152/japplphysiol.90719.2008

Publications 2008

Bjornstad JL, Neverdal NO, Vengen OA, Knudsen CW, Husebye T, Pepper J, Lie M, Christensen G, Tonnessen T (2008)
Alterations in circulating activin A, GDF-15, TGF-beta 3 and MMP-2,-3, and-9 during one year of left ventricular reverse remodelling in patients operated for severe aortic stenosis
Eur. J. Heart Fail., 10 (12), 1201-1207
DOI 10.1016/j.ejheart.2008.09.010

Husberg C, Nygard S, Finsen AV, Damas JK, Frigessi A, Oie E, Waehre A, Gullestad L, Aukrust P, Yndestad A, Christensen G (2008)
Cytokine expression profiling of the myocardium reveals a role for CX3CL1 (fractalkine) in heart failure
J. Mol. Cell. Cardiol., 45 (2), 261-269
DOI 10.1016/j.yjmcc.2008.05.009

Larsen KO, Lygren B, Sjaastad I, Krobert KA, Arnkvaern K, Florholmen G, Larsen AKR, Levy FO, Tasken K, Skjonsberg OH, Christensen G (2008)
Diastolic dysfunction in alveolar hypoxia: a role for interleukin-18-mediated increase in protein phosphatase 2A
Cardiovasc. Res., 80 (1), 47-54
DOI 10.1093/cvr/cvn180

Publications 2007

Van Geest GJ, Hessen DO, Spierenburg P, Dahl-Hansen GAP, Christensen G, Faerovig PJ, Brehm M, Loonen MJJE, Van Donk E (2007)
Goose-mediated nutrient enrichment and planktonic grazer control in arctic freshwater ponds
Oecologia, 153 (3), 653-662
DOI 10.1007/s00442-007-0770-7

Publications 2006

Andersson KB, Florholmen G, Winer LH, Tonnessen T, Christensen G (2006)
Regulation of neuronal type genes in congestive heart failure rats
Acta Physiol., 186 (1), 17-27
DOI 10.1111/j.1748-1716.2005.01503.x

Florholmen G, Halvorsen B, Beraki K, Lyberg T, Sagen EL, Aukrust P, Christensen G, Yndestad A (2006)
Activin A inhibits organization of sarcomeric proteins in cardiomyocytes induced by leukemia inhibitory factor
J. Mol. Cell. Cardiol., 41 (4), 689-697
DOI 10.1016/j.yjmcc.2006.07.009

Florholmen G, Thoresen GH, Rustan AC, Jensen J, Christensen G, Aas V (2006)
Leukaemia inhibitory factor stimulates glucose transport in isolated cardiomyocytes and induces insulin resistance after chronic exposure
Diabetologia, 49 (4), 724-731
DOI 10.1007/s00125-006-0150-6

Larsen KO, Sjaastad I, Svindland A, Krobert KA, Skjonsberg OH, Christensen G (2006)
Alveolar hypoxia induces left ventricular diastolic dysfunction and reduces phosphorylation of phospholamban in mice
Am. J. Physiol.-Heart Circul. Physiol., 291 (2), H507-H516
DOI 10.1152/ajpheart.00862.2005

Lunde PK, Sejersted OM, Thorud HMS, Tonnessen T, Henriksen UL, Christensen G, Westerblad H, Bruton J (2006)
Effects of congestive heart failure on Ca2+ handling in skeletal muscle during fatigue
Circ.Res., 98 (12), 1514-1519
DOI 10.1161/01.RES.0000226529.66545.e5

Madsen LH, Christensen G, Lund T, Serebruany VL, Granger CB, Hoen I, Grieg Z, Alexander JH, Jaffe AS, Van Eyk JE, Atar D (2006)
Time course of degradation of cardiac troponin I in patients with acute ST-elevation myocardial infarction - The ASSENT-2 troponin substudy
Circ.Res., 99 (10), 1141-1147
DOI 10.1161/01.RES.0000249531.23654.e1

Publications 2005

Finsen AV, Christensen G, Sjaastad I (2005)
Echocardiographic parameters discriminating myocardial infarction with pulmonary congestion from myocardial infarction without congestion in the mouse
J. Appl. Physiol., 98 (2), 680-689
DOI 10.1152/japplphysiol.00924.2004

Iversen PO, Woldbaek PR, Christensen G (2005)
Reduced immune responses to an aseptic inflammation in mice with congestive heart failure
Eur. J. Haematol., 75 (2), 156-163
DOI 10.1111/j.1600-0609.2005.00440.x

Ueland T, Yndestad A, Oie E, Florholmen G, Halvorsen B, Froland SS, Simonsen S, Christensen G, Gullestad L, Aukrust P (2005)
Dysregulated osteoprotegerin/RANK ligand/RANK axis in clinical and experimental heart failure
Circulation, 111 (19), 2461-2468
DOI 10.1161/01.CIR.0000165119.62099.14

Woldbaek PR, Sande JB, Stromme TA, Lunde PK, Djurovic S, Lyberg T, Christensen G, Tonnessen T (2005)
Daily administration of interleukin-18 causes myocardial dysfunction in healthy mice
Am. J. Physiol.-Heart Circul. Physiol., 289 (2), H708-H714
DOI 10.1152/ajpheart.01179.2004

Publications 2004

Djurovic S, Iversen N, Jeansson S, Hoover F, Christensen G (2004)
Comparison of nonviral transfection and adeno-associated viral transduction on cardiomyocytes
Mol. Biotechnol., 28 (1), 21-31
DOI 10.1385/MB:28:1:21

Finsen AV, Woldbaek PR, Li J, Wu JP, Lyberg T, Tonnessen T, Christensen G (2004)
Increased syndecan expression following myocardial infarction indicates a role in cardiac remodeling
Physiol. Genomics, 16 (3), 301-308
DOI 10.1152/physiolgenomics.00144.2002

Florholmen G, Andersson KB, Yndestad A, Austbo B, Henriksen UL, Christensen G (2004)
Leukaemia inhibitory factor alters expression of genes involved in rat cardiomyocyte energy metabolism
Acta Physiol. Scand., 180 (2), 133-142
DOI 10.1046/j.0001-6772.2003.01245.x

Florholmen G, Aas V, Rustan AC, Lunde PK, Straumann N, Eid H, Odegaard A, Dishington H, Andersson KB, Christensen G (2004)
Leukemia inhibitory factor reduces contractile function and induces alterations in energy metabolism in isolated cardiomyocytes
J. Mol. Cell. Cardiol., 37 (6), 1183-1193
DOI 10.1016/j.yjmcc.2004.09.008

Yndestad A, Ueland T, Oie E, Florholmen G, Halvorsen B, Attramadal H, Simonsen S, Froland SS, Gullestad L, Christensen G, Damas JK, Aukrust P (2004)
Elevated levels of activin A in heart failure - Potential role in myocardial remodeling
Circulation, 109 (11), 1379-1385
DOI 10.1161/01.CIR.0000120704.97934.41

Publications 2003

Salbu B, Skipperud L, Germain P, Guegueniat P, Strand P, Lind OC, Christensen G (2003)
Radionuclide speciation in effluent from La Hague reprocessing plant in France
Health Phys., 85 (3), 311-322
DOI 10.1097/00004032-200309000-00007

Tonnessen T, Florholmen G, Henriksen UL, Christensen G (2003)
Cardiopulmonary alterations in mRNA expression for interteukin-1 beta, the interleukin-6 superfamity and CXC-chemokines during development of postischaemic heart failure in the rat
Clin. Physiol. Funct. Imaging, 23 (5), 263-268
DOI 10.1046/j.1475-097X.2003.00503.x

Woldbaek PR, Stromme TA, Sande JB, Christensen G, Tonnessen T, Ilebekk A (2003)
Evaluation of a new fiber-optic pressure recording system for cardiovascular measurements in mice
Am. J. Physiol.-Heart Circul. Physiol., 285 (5), H2233-H2239
DOI 10.1152/ajpheart.01123.2002

Woldbaek PR, Tonnessen T, Henriksen UL, Florholmen G, Lunde PK, Lyberg T, Christensen G (2003)
Increased cardiac IL-18 mRNA, pro-IL-18 and plasma IL-18 after myocardial infarction in the mouse; a potential role in cardiac dysfunction
Cardiovasc. Res., 59 (1), 122-131
DOI 10.1016/S0008-6363(03)00339-0

Publications 2002

Finsnes F, Lyberg T, Christensen G, Skjonsberg OH (2002)
Leukotriene antagonism reduces the generation of endothelin-l and interferon-gamma and inhibits eosinophilic airway inflammation
Respir. Med., 96 (11), 901-906
DOI 10.1053/rmed.2002.1375

Iversen PO, Woldbaek PR, Tonnessen T, Christensen G (2002)
Decreased hematopoiesis in bone marrow of mice with congestive heart failure
Am. J. Physiol.-Regul. Integr. Comp. Physiol., 282 (1), R166-R172
DOI 10.1152/ajpregu.2002.282.1.R166

Sande JB, Sjaastad I, Hoen IB, Bokenes J, Tonnessen T, Holt E, Lunde PK, Christensen G (2002)
Reduced level of serine(16) phosphorylated phospholamban in the failing rat myocardium: a major contributor to reduced SERCA2 activity
Cardiovasc. Res., 53 (2), PII S0008-6363(01)00489-8-391
DOI 10.1016/S0008-6363(01)00489-8

Thorud HMS, Wisloff U, Lunde PK, Christensen G, Ellingsen O, Sejersted OM (2002)
Surgical manipulation, but not moderate exercise, is associated with increased cytokine mRNA expression in the rat soleus muscle
Acta Physiol. Scand., 175 (3), 219-226
DOI 10.1046/j.1365-201X.2002.00990.x

Woldbaek PR, Hoen IB, Christensen G, Tonnessen T (2002)
Gene expression of colony-stimulating factors and stem cell factor after myocardial infarction in the mouse
Acta Physiol. Scand., 175 (3), 173-181
DOI 10.1046/j.1365-201X.2002.00989.x

Publications 2001

Damas JK, Aukrust P, Ueland T, Odegaard A, Eiken HG, Gullestad L, Sejersted OM, Christensen G (2001)
Monocyte chemoattractant protein-1 enhances and interleukin-10 suppresses the production of inflammatory cytokines in adult rat cardiomyocytes
Basic Res. Cardiol., 96 (4), 345-352
DOI 10.1007/s003950170042

Eiken HG, Oie E, Damas JK, Yndestad A, Bjerkeli V, Aass H, Simonsen S, Geiran OR, Tonnessen T, Christensen G, Froland SS, Gullestad L, Attramadal H, Aukrust P (2001)
Myocardial gene expression of leukaemia inhibitory factor, interleukin-6 and glycoprotein 130 in end-stage human heart failure
Eur. J. Clin. Invest., 31 (5), 389-397
DOI 10.1046/j.1365-2362.2001.00795.x

Finsnes F, Lyberg T, Christensen G, Skjonsberg OH (2001)
Effect of endothelin antagonism on the production of cytokines in eosinophilic airway inflammation
Am. J. Physiol.-Lung Cell. Mol. Physiol., 280 (4), L659-L665
DOI 10.1152/ajplung.2001.280.4.L659

Leistad E, Ohmori K, Peterson TA, Christensen G, DeMaria AN (2001)
Quantitative assessment of myocardial perfusion during graded coronary artery stenoses by intravenous myocardial contrast echocardiography
J. Am. Coll. Cardiol., 37 (2), 624-631
DOI 10.1016/S0735-1097(00)01127-X

Publications 2000

Christensen G, Minamisawa S, Gruber PJ, Wang YB, Chien KR (2000)
High-efficiency, long-term cardiac expression of foreign genes in living mouse embryos and neonates
Circulation, 101 (2), 178-184
DOI 10.1161/01.CIR.101.2.178

Damas JK, Eiken HG, Oie E, Bjerkeli V, Yndestad A, Ueland T, Tonnessen T, Geiran OR, Aass H, Simonsen S, Christensen G, Froland SS, Attramadal H, Gullestad L, Aukrust P (2000)
Myocardial expression of CC- and CXC-chemokines and their receptors in human end-stage heart failure
Cardiovasc. Res., 47 (4), 778-787
DOI 10.1016/S0008-6363(00)00142-5

Finsnes F, Skjonsberg OH, Lyberg T, Christensen G (2000)
Endothelin-1 production is associated with eosinophilic rather than neutrophilic airway inflammation
Eur. Resp. J., 15 (4), 743-750
DOI 10.1034/j.1399-3003.2000.15d19.x

Tonnessen T, Lyberg T, Geiran O, Christensen G (2000)
Cardiac endothelin-like immunoreactivity and preproendothelin-1 mRNA expression in human heart failure
Scand. Cardiovasc. J., 34 (1), 21-27

Publications 1999

Holt E, Sjaastad I, Lunde PK, Christensen G, Sejersted OM (1999)
Thyroid hormone control of contraction and the Ca2+-ATPase/phospholamban complex in adult rat ventricular myocytes
J. Mol. Cell. Cardiol., 31 (3), 645-656
DOI 10.1006/jmcc.1998.0900

Publications 1998

Dybkjaer L, Paisley LG, Vraa-Andersen L, Christensen G (1998)
Associations between behavioural indicators of 'stress' in weaner pigs and respiratory lesions at slaughter
Prev. Vet. Med., 34 (2-3), 175-190
DOI 10.1016/S0167-5877(97)00074-3

Finsnes F, Christensen G, Lyberg T, Sejersted OM, Skjonsberg OH (1998)
Increased synthesis and release of endothelin-1 during the initial phase of airway inflammation
Am. J. Respir. Crit. Care Med., 158 (5), 1600-1606
DOI 10.1164/ajrccm.158.5.9707082

Holt E, Tonnessen T, Lunde PK, Semb SO, Wasserstrom JA, Sejersted OM, Christensen G (1998)
Mechanisms of cardiomyocyte dysfunction in heart failure following myocardial infarction in rats
J. Mol. Cell. Cardiol., 30 (8), 1581-1593
DOI 10.1006/jmcc.1998.0724

Semb SO, Lunde PK, Holt E, Tonnessen T, Christensen G, Sejersted OM (1998)
Reduced myocardial Na+, K+-pump capacity in congestive heart failure following myocardial infarction in rats
J. Mol. Cell. Cardiol., 30 (7), 1311-1328

Tonnessen T, Lunde PK, Giaid A, Sejersted OM, Christensen G (1998)
Pulmonary and cardiac expression of preproendothelin-1 mRNA are increased in heart failure after myocardial infarction in rats. Localization of preproendothelin-1 mRNA and endothelin peptide
Cardiovasc. Res., 39 (3), 633-643
DOI 10.1016/S0008-6363(98)00156-4

Publications 1997

Christensen G, Leistad E (1997)
Atrial systolic pressure, as well as stretch, is a principal stimulus for release of ANF
Am. J. Physiol.-Heart Circul. Physiol., 272 (2), H820-H826
DOI 10.1152/ajpheart.1997.272.2.H820

Finsnes F, Skjonsberg OH, Tonnessen T, Naess O, Lyberg T, Christensen G (1997)
Endothelin production and effects of endothelin antagonism during experimental airway inflammation
Am. J. Respir. Crit. Care Med., 155 (4), 1404-1412
DOI 10.1164/ajrccm.155.4.9105086

Holt E, Christensen G (1997)
Transient Ca2+ overload alters Ca2+ handling in rat cardiomyocytes: effects on shortening and relaxation
Am. J. Physiol.-Heart Circul. Physiol., 273 (2), H573-H582
DOI 10.1152/ajpheart.1997.273.2.H573

Holt E, Lunde PK, Sejersted OM, Christensen G (1997)
Electrical stimulation of adult rat cardiomyocytes in culture improves contractile properties and is associated with altered calcium handling
Basic Res. Cardiol., 92 (5), 289-298
DOI 10.1007/s003950050038

Oie E, Vinge LE, Tonnessen T, Grogaard HK, Kjekshus H, Christensen G, Smiseth OA, Attramadal H (1997)
Transient, isopeptide-specific induction of myocardial endothelin-1 mRNA in congestive heart failure in rats
Am. J. Physiol.-Heart Circul. Physiol., 273 (4), H1727-H1736

Tonnessen T, Christensen G, Oie E, Holt E, Kjekshus H, Smiseth OA, Sejersted OM, Attramadal H (1997)
Increased cardiac expression of endothelin-1 mRNA in ischemic heart failure in rats
Cardiovasc. Res., 33 (3), 601-610
DOI 10.1016/S0008-6363(96)00266-0

Publications 1996

Leistad E, Aksnes G, Verburg E, Christensen G (1996)
Atrial contractile dysfunction after short-term atrial fibrillation is reduced by verapamil but increased by BAY K8644
Circulation, 93 (9), 1747-1754
DOI 10.1161/01.CIR.93.9.1747

Naess PA, Bugge JF, Christensen G (1996)
Lack of inhibitory effect of atrial natriuretic factor on renin release induced by renal hypotension
Scand. J. Clin. Lab. Invest., 56 (7), 665-670
DOI 10.3109/00365519609090603

Tonnessen T, Ilebekk A, Naess PA, Christensen G (1996)
Inhibition of granulocyte-derived proteases reduces the increase in plasma endothelin associated with myocardial ischemia in the pig
Basic Res. Cardiol., 91 (4), 289-295
DOI 10.1007/BF00789301

Publications 1995

TONNESSEN T, GIAID A, SALEH D, NAESS PA, YANAGISAWA M, CHRISTENSEN G (1995)
INCREASED IN-VIVO EXPRESSION AND PRODUCTION OF ENDOTHELIN-1 BY PORCINE CARDIOMYOCYTES SUBJECTED TO ISCHEMIA
Circ.Res., 76 (5), 767-772

Tønnessen T, Schlichting E, Lyberg T, Christensen G (1995)
Endothelin release associated with splanchnic ischemia is abolished by inhibition of leukocyte-derived proteases
Endothelium, 3, 225-234
DOI 10.3109/10623329509024668, PublikaID 318

Publications 1994

Christensen G (1994)
PACSUS - PACS for Ullevål sykehus
Trondheim
BIBSYS 952210738

Christensen G, Lunde GH (1994)
Internprising for bedre økonomisk styring: internprisingspraksis i fire bilfirma sammenlignet med teorien på området
[Forfatterne], Bergen, 53 bl.
BIBSYS 942419294

KIRKEBOEN KA, ILEBEKK A, TONNESSEN T, LEISTAD E, NAESS PA, CHRISTENSEN G, AKSNES G (1994)
CARDIAC CONTRACTILE FUNCTION FOLLOWING REPETITIVE BRIEF ISCHEMIA - EFFECTS OF NUCLEOSIDE TRANSPORT INHIBITION
Am. J. Physiol., 267 (1), H57-H65
DOI 10.1152/ajpheart.1994.267.1.H57

STRAND P, NIKITIN A, RUDJORD AL, SALBU B, CHRISTENSEN G, FOYN L, KRYSHEV II, CHUMICHEV VB, DAHLGAARD H, HOLM E (1994)
SURVEY OF ARTIFICIAL RADIONUCLIDES IN THE BARENTS SEA AND THE KARA SEA
J. Environ. Radioact., 25 (1-2), 99-112
DOI 10.1016/0265-931X(94)90010-8

TONNESSEN T, NAESS PA, KIRKEBOEN KA, ILEBEKK A, CHRISTENSEN G (1994)
ENDOTHELIN SECRETION BY ENDOCARDIAL ENDOTHELIAL-CELLS - RESPONSE
Cardiovasc. Res., 28 (5), 722
DOI 10.1093/cvr/28.5.722a

Publications 1993

CHRISTENSEN G (1993)
RELEASE OF ATRIAL-NATRIURETIC-FACTOR
Scand. J. Clin. Lab. Invest., 53 (2), 91-100
DOI 10.3109/00365519309088395

CHRISTENSEN G (1993)
CARDIOVASCULAR AND RENAL EFFECTS OF ATRIAL-NATRIURETIC-FACTOR
Scand. J. Clin. Lab. Invest., 53 (3), 203-209
DOI 10.3109/00365519309088410

GROTMOL T, RODNES JT, BUANES T, CHRISTENSEN G, LANDSVERK T (1993)
ATRIAL-NATRIURETIC-FACTOR (ANF) DOES NOT AFFECT ION-TRANSPORT IN HUMAN INTESTINE BUT DOES IN PORCINE INTESTINE
Acta Physiol. Scand., 147 (4), 417-429
DOI 10.1111/j.1748-1716.1993.tb09517.x

ILEBEKK A, CHRISTENSEN G, LEISTAD E, RUTLEN DL (1993)
ATRIAL-NATRIURETIC-FACTOR INCREASES PERITONEAL-FLUID FORMATION IN THE PIG
Acta Physiol. Scand., 149 (1), 121-122
DOI 10.1111/j.1748-1716.1993.tb09601.x

LEISTAD E, CHRISTENSEN G, ILEBEKK A (1993)
ATRIAL CONTRACTILE PERFORMANCE AFTER CESSATION OF ATRIAL-FIBRILLATION
Am. J. Physiol., 264 (1), H104-H109
DOI 10.1152/ajpheart.1993.264.1.H104

LEISTAD E, CHRISTENSEN G, ILEBEKK A (1993)
EFFECTS OF ATRIAL-FIBRILLATION ON LEFT AND RIGHT ATRIAL DIMENSIONS, PRESSURES, AND COMPLIANCES
Am. J. Physiol., 264 (4), H1093-H1097

LEISTAD E, CHRISTENSEN G, ILEBEKK A (1993)
SIGNIFICANCE OF INCREASED ATRIAL PRESSURE ON STROKE VOLUME DURING ATRIAL-FIBRILLATION IN ANESTHETIZED PIGS
Acta Physiol. Scand., 149 (2), 157-161
DOI 10.1111/j.1748-1716.1993.tb09608.x

NAESS PA, CHRISTENSEN G, KIIL F (1993)
INHIBITORY EFFECT OF ENDOTHELIN ON RENIN RELEASE IN DOG KIDNEYS
Acta Physiol. Scand., 148 (2), 131-136
DOI 10.1111/j.1748-1716.1993.tb09542.x

NAESS PA, CHRISTENSEN G, KIRKEBOEN KA, KIIL F (1993)
EFFECT ON RENIN RELEASE OF INHIBITING RENAL NITRIC-OXIDE SYNTHESIS IN ANESTHETIZED DOGS
Acta Physiol. Scand., 148 (2), 137-142
DOI 10.1111/j.1748-1716.1993.tb09543.x

TONNESSEN T, NAESS PA, KIRKEBOEN KA, ILEBEKK A, CHRISTENSEN G (1993)
ALTERATIONS IN PLASMA ENDOTHELIN DURING PASSAGE THROUGH THE LEFT-HEART CHAMBERS BEFORE AND AFTER BRIEF MYOCARDIAL-ISCHEMIA
Cardiovasc. Res., 27 (12), 2160-2163
DOI 10.1093/cvr/27.12.2160

TONNESSEN T, NAESS PA, KIRKEBOEN KA, OFFSTAD J, ILEBEKK A, CHRISTENSEN G (1993)
RELEASE OF ENDOTHELIN FROM THE PORCINE HEART AFTER SHORT-TERM CORONARY-ARTERY OCCLUSION
Cardiovasc. Res., 27 (8), 1482-1485
DOI 10.1093/cvr/27.8.1482

TONNESSEN T, NAESS PA, KIRKEBOEN KA, OFFSTAD J, ILEBEKK A, CHRISTENSEN G (1993)
ENDOTHELIN IS RELEASED FROM THE PORCINE CORONARY CIRCULATION AFTER SHORT-TERM ISCHEMIA
J. Cardiovasc. Pharmacol., 22 8, S313-S316
DOI 10.1097/00005344-199322008-00082

Publications 1992

AKSNES G, KIRKEBOEN KA, CHRISTENSEN G, ILEBEKK A (1992)
CHARACTERISTICS AND DEVELOPMENT OF MYOCARDIAL STUNNING IN THE PIG
Am. J. Physiol., 263 (2), H544-H551
DOI 10.1152/ajpheart.1992.263.2.H544

Christensen G (1992)
Atrial natriuretic factor: an experimental study on release mechanisms and on cardiovascular and renal effects
[Universitetet i Oslo, Institutt for eksperiementell medisinsk forskning], Oslo, 1 b. (flere pag.)
BIBSYS 930211189, ISBN 82-90246-39-0

CHRISTENSEN G, BUGGE JF, OSTENSEN J, KIIL F (1992)
ATRIAL-NATRIURETIC-FACTOR AND RENAL SODIUM-EXCRETION DURING VENTILATION WITH PEEP IN HYPERVOLEMIC DOGS
J. Appl. Physiol., 72 (3), 993-997
DOI 10.1152/jappl.1992.72.3.993

KIRKEBOEN KA, NAESS PA, CHRISTENSEN G, KIIL F (1992)
IMPORTANCE OF NITRIC-OXIDE IN CANINE FEMORAL CIRCULATION - COMPARISON OF 2 NO INHIBITORS
Cardiovasc. Res., 26 (4), 357-361
DOI 10.1093/cvr/26.4.357

NAESS PA, CHRISTENSEN G, KIRKEBOEN KA, KIIL F (1992)
EFFECT OF ATRIAL-NATRIURETIC-FACTOR ON RENAL PROSTAGLANDIN-E2 RELEASE IN THE ANESTHETIZED DOG
Acta Physiol. Scand., 145 (4), 369-375
DOI 10.1111/j.1748-1716.1992.tb09377.x

NAESS PA, KIRKEBOEN KA, CHRISTENSEN G, KIIL F (1992)
INHIBITION OF RENAL NITRIC-OXIDE SYNTHESIS WITH N(G)-MONOMETHYL-L-ARGININE AND N(G)-NITRO-L-ARGININE
Am. J. Physiol., 262 (6), F939-F942
DOI 10.1152/ajprenal.1992.262.6.F939

Publications 1991

CHRISTENSEN G, AKSNES G, ILEBEKK A, KIIL F (1991)
RELEASE OF ATRIAL-NATRIURETIC-FACTOR DURING SELECTIVE CARDIAC ALPHA-ADRENERGIC AND BETA-ADRENERGIC STIMULATION, INTRACORONARY CA2+ INFUSION, AND AORTIC CONSTRICTION IN PIGS
Circ.Res., 68 (3), 638-644
DOI 10.1161/01.RES.68.3.638

HYSING J, GORDELADZE JO, CHRISTENSEN G, TOLLESHAUG H (1991)
RENAL UPTAKE AND DEGRADATION OF TRAPPED-LABEL CALCITONIN
Biochem. Pharmacol., 41 (8), 1119-1126
DOI 10.1016/0006-2952(91)90649-P

LEISTAD E, CHRISTENSEN G, ILEBEKK A (1991)
RIGHT AND LEFT ATRIAL DIAMETERS DURING INCREMENTAL ATRIAL-PACING IN PIGS
Am. J. Physiol., 260 (3), H973-H978
DOI 10.1152/ajpheart.1991.260.3.H973

NAESS PA, CHRISTENSEN G, KIIL F (1991)
ATRIAL-NATRIURETIC-FACTOR REDUCES RENIN RELEASE BY OPPOSING ALPHA-ADRENOCEPTOR ACTIVITY
Am. J. Physiol., 261 (2), E240-E245
DOI 10.1152/ajpendo.1991.261.2.E240

Publications 1990

RUTLEN DL, HELGESEN KG, CHRISTENSEN G, VENGEN OA, ILEBEKK A (1990)
INFLUENCE OF ANGIOTENSIN ON TOTAL INTRAVASCULAR CAPACITY IN THE ANESTHETIZED PIG
Acta Physiol. Scand., 139 (4), 569-573
DOI 10.1111/j.1748-1716.1990.tb08960.x

Publications 1989

CHRISTENSEN G, BUGGE JF, ILEBEKK A, KIIL F (1989)
ATRIAL NATRIURETIC FACTOR INDUCES NATRIURESIS DURING PACING TACHYCARDIA IN DOGS
Am. J. Physiol., 256 (6), R1245-R1249

CHRISTENSEN G, ILEBEKK A, KIIL F (1989)
RELEASE OF ATRIAL NATRIURETIC FACTOR DURING INFUSION OF ISOPROTERENOL AND ANGIOTENSIN-II
Am. J. Physiol., 257 (4), R896-R900
DOI 10.1152/ajpregu.1989.257.4.R896

Publications 1988

CHRISTENSEN G, ILEBEKK A, AAKESON I, KIIL F (1988)
THE RELEASE MECHANISM FOR ATRIAL NATRIURETIC FACTOR DURING BLOOD-VOLUME EXPANSION AND TACHYCARDIA IN DOGS
Acta Physiol. Scand., 134 (2), 263-270
DOI 10.1111/j.1748-1716.1988.tb08487.x