Publications 2022

Carlson CR, Aronsen JM, Bergan-Dahl A, Moutty MC, Lunde M, Lunde PK, Jarstadmarken H, Wanichawan P, Pereira L, Kolstad TRS, Dalhus B, Subramanian H, Hille S, Christensen G, Muller OJ, Nikolaev V, Bers DM, Sjaastad I, Shen X, Louch WE, Klussmann E, Sejersted OM (2022)
AKAP18 delta Anchors and Regulates CaMKII Activity at Phospholamban-SERCA2 and RYR
Circ.Res., 130 (1), 27-44
DOI 10.1161/CIRCRESAHA.120.317976

Lunde IG, Skrbic B, Sjaastad I, Christensen G, Carlson CR, Tønnessen T (2022)
Calcineurin-NFAT dynamics correspond to cardiac remodeling during aortic banding and debanding, mimicking aortic valve replacement
Front Mol Med, 2, 1-14
DOI 10.3389/fmmed.2022.980717, PublikaID 435

Publications 2021

Wanichawan P, Skogestad J, Lunde M, Stole TP, Stensland M, Nyman TA, Sjaastad I, Sejersted OM, Aronsen JM, Carlson CR (2021)
Design of a Proteolytically Stable Sodium-Calcium Exchanger 1 Activator Peptide for In Vivo Studies
Front. Pharmacol., 12, 638646
DOI 10.3389/fphar.2021.638646

Publications 2020

Herum KM, Romaine A, Wang A, Melleby AO, Strand ME, Pacheco J, Braathen B, Duner P, Tonnessen T, Lunde IG, Sjaastad I, Brakebusch C, McCulloch AD, Gomez MF, Carlson CR, Christensen G (2020)
Syndecan-4 Protects the Heart From the Profibrotic Effects of Thrombin-Cleaved Osteopontin
J. Am. Heart Assoc., 9 (3), e013518
DOI 10.1161/JAHA.119.013518

Mathiesen SB, Lunde M, Stensland M, Martinsen M, Nyman TA, Christensen G, Carlson CR (2020)
The Cardiac Syndecan-2 Interactome
Front. Cell. Dev. Biol., 8, 792
DOI 10.3389/fcell.2020.00792

Ronning SB, Carlson CR, Aronsen JM, Pisconti A, Host V, Lunde M, Liland KH, Sjaastad I, Kolset SO, Christensen G, Pedersen ME (2020)
Syndecan-4(-/-)Mice Have Smaller Muscle Fibers, Increased Akt/mTOR/S6K1 and Notch/HES-1 Pathways, and Alterations in Extracellular Matrix Components
Front. Cell. Dev. Biol., 8, 730
DOI 10.3389/fcell.2020.00730

Skogestad J, Aronsen JM, Tovsrud N, Wanichawan P, Hougen K, Stokke MK, Carlson CR, Sjaastad I, Sejersted OM, Swift F (2020)
Coupling of the Na+/K+-ATPase to Ankyrin B controls Na+/Ca2+ exchanger activity in cardiomyocytes
Cardiovasc. Res., 116 (1), 78-90
DOI 10.1093/cvr/cvz087

Publications 2019

Mathiesen SB, Lunde M, Aronsen JM, Romaine A, Kaupang A, Martinsen M, de Souza GA, Nyman TA, Sjaastad I, Christensen G, Carlson CR (2019)
The cardiac syndecan-4 interactome reveals a role for syndecan-4 in nuclear translocation of muscle LIM protein (MLP)
J. Biol. Chem., 294 (22), 8717-8731
DOI 10.1074/jbc.RA118.006423

Ottesen AH, Carlson CR, Eken OS, Sadredini M, Myhre PL, Shen X, Dalhus B, Laver DR, Lunde PK, Kurola J, Lunde M, Hoff JE, Godang K, Sjaastad I, Pettila V, Stridsberg M, Lehnart SE, Edwards AG, Lunde IG, Omland T, Stokke MK, Christensen G, Rosjo H, Louch WE (2019)
Secretoneurin Is an Endogenous Calcium/Calmodulin-Dependent Protein Kinase II Inhibitor That Attenuates Ca2+-Dependent Arrhythmia
Circ.-Arrhythmia Electrophysiol., 12 (4), e007045
DOI 10.1161/CIRCEP.118.007045

Shen X, van den Brink J, Hou YF, Colli D, Le C, Kolstad TR, MacQuaide N, Carlson CR, Kekenes-Huskey PM, Edwards AG, Soeller C, Louch WE (2019)
3D dSTORM imaging reveals novel detail of ryanodine receptor localization in rat cardiac myocytes
J. Physiol.-London, 597 (2), 399-418
DOI 10.1113/JP277360

Udjus C, Cero FT, Halvorsen B, Behmen D, Carlson CR, Bendiksen BA, Espe EKS, Sjaastad I, Loberg EM, Yndestad A, Aukrust P, Christensen G, Skjonsberg OH, Larsen KO (2019)
Caspase-1 induces smooth muscle cell growth in hypoxia-induced pulmonary hypertension
Am. J. Physiol.-Lung Cell. Mol. Physiol., 316 (6), L999-L1012
DOI 10.1152/ajplung.00322.2018

Publications 2018

Fan Q, Moen A, Anonsen JH, Bindesboll C, Saether T, Carlson CR, Gronning-Wang LM (2018)
O-G1cNAc site-mapping of liver X receptor-alpha and O-G1cNAc transferase
Biochem. Biophys. Res. Commun., 499 (2), 354-360
DOI 10.1016/j.bbrc.2018.03.164

Simon DN, Wriston A, Fan Q, Shabanowitz J, Florwick A, Dharmaraj T, Peterson SB, Gruenbaum Y, Carlson CR, Gronning-Wang LM, Hunt DF, Wilson KL (2018)
OGT (O-GlcNAc Transferase) Selectively Modifies Multiple Residues Unique to Lamin A
Cells, 7 (5), 44
DOI 10.3390/cells7050044

Publications 2017

Hafver TL, Wanichawan P, Manfra O, de Souza GA, Lunde M, Martinsen M, Louch WE, Sejersted OM, Carlson CR (2017)
Mapping the in vitro interactome of cardiac sodium (Na+)-calcium (Ca2+) exchanger 1 (NCX1)
Proteomics, 17 (17-18), 1600417
DOI 10.1002/pmic.201600417

Lubner JM, Dodge-Kafka KL, Carlson CR, Church GM, Chou MF, Schwartz D (2017)
Cushing's syndrome mutant PKA(L205R) exhibits altered substrate specificity
FEBS Lett., 591 (3), 459-467
DOI 10.1002/1873-3468.12562

Ottesen AH, Carlson CR, Louch WE, Dahl MB, Sandbu RA, Johansen RF, Jarstadmarken H, Bjoras M, Hoiseth AD, Brynildsen J, Sjaastad I, Stridsberg M, Omland T, Christensen G, Rosjo H (2017)
Glycosylated Chromogranin A in Heart Failure Implications for Processing and Cardiomyocyte Calcium Homeostasis
Circ.-Heart Fail., 10 (2)
DOI 10.1161/CIRCHEARTFAILURE.116.003675

Weber JJ, Golla M, Guaitoli G, Wanichawan P, Hayer SN, Hauser S, Krahl AC, Nagel M, Samer S, Aronica E, Carlson CR, Schols L, Riess O, Gloeckner CJ, Nguyen HP, Hubener-Schmid J (2017)
A combinatorial approach to identify calpain cleavage sites in the Machado-Joseph disease protein ataxin-3
Brain, 140, 1280-1299
DOI 10.1093/brain/awx039

Publications 2016

Hafver TL, Hodne K, Wanichawan P, Aronsen JM, Dalhus B, Lunde PK, Lunde M, Martinsen M, Enger UH, Fuller W, Sjaastad I, Louch WE, Sejersted OM, Carlson CR (2016)
Protein Phosphatase 1c Associated with the Cardiac Sodium Calcium Exchanger 1 Regulates Its Activity by Dephosphorylating Serine 68-phosphorylatedPhospholemman
J. Biol. Chem., 291 (9), 4561-4579
DOI 10.1074/jbc.M115.677898

Manotheepan R, Danielsen TK, Sadredini M, Anderson ME, Carlson CR, Lehnart SE, Sjaastad I, Stokke MK (2016)
Exercise training prevents ventricular tachycardia in CPVT1 due to reduced CaMKII-dependent arrhythmogenic Ca2+ release
Cardiovasc. Res., 111 (3), 295-306
DOI 10.1093/cvr/cvw095

Wanichawan P, Hodne K, Hafver TL, Lunde M, Martinsen M, Louch WE, Sejersted OM, Carlson CR (2016)
Development of a high-affinity peptide that prevents phospholemman (PLM) inhibition of the sodium/calcium exchanger 1 (NCX1)
Biochem. J., 473, 2413-2423
DOI 10.1042/BCJ20160465

Publications 2015

Ottesen AH, Louch WE, Carlson CR, Landsverk OJB, Kurola J, Johansen RF, Moe MK, Aronsen JM, Hoiseth AD, Jarstadmarken H, Nygard S, Bjoras M, Sjaastad I, Pettila V, Stridsberg M, Omland T, Christensen G, Rosjo H (2015)
Secretoneurin Is a Novel Prognostic Cardiovascular Biomarker Associated With Cardiomyocyte Calcium Handling
J. Am. Coll. Cardiol., 65 (4), 339-351
DOI 10.1016/j.jacc.2014.10.065

Ronning SB, Carlson CR, Stang E, Kolset SO, Hollung K, Pedersen ME (2015)
Syndecan-4 Regulates Muscle Differentiation and Is Internalized from the Plasma Membrane during Myogenesis
PLoS One, 10 (6), e0129288
DOI 10.1371/journal.pone.0129288

Skrbic B, Engebretsen KVT, Strand ME, Lunde IG, Herum KM, Marstein HS, Sjaastad I, Lunde PK, Carlson CR, Christensen G, Bjornstad JL, Tonnessen T (2015)
Lack of collagen VIII reduces fibrosis and promotes early mortality and cardiac dilatation in pressure overload in mice
Cardiovasc. Res., 106 (1), 32-42
DOI 10.1093/cvr/cvv041

Tinholt M, Stavik B, Louch W, Carlson CR, Sletten M, Ruf W, Skretting G, Sandset PM, Iversen N (2015)
Syndecan-3 and TFPI Colocalize on the Surface of Endothelial-, Smooth Muscle-, and Cancer Cells
PLoS One, 10 (1), e0117404
DOI 10.1371/journal.pone.0117404

Publications 2014

Aspelin T, Eriksen M, Ilebekk A, Cataliotti A, Carlson CR, Lyberg T (2014)
beta-blockade abolishes the augmented cardiac tPA release induced by transactivation of heterodimerised bradykinin receptor-2 and beta(2)-adrenergic receptor in vivo
Thromb. Haemost., 112 (5), 951-959
DOI 10.1160/TH14-01-0059

Berk JM, Simon DN, Jenkins-Houk CR, Westerbeck JW, Gronning-Wang LM, Carlson CR, Wilson KL (2014)
The molecular basis of emerin-emerin and emerin-BAF interactions
J. Cell Sci., 127 (18), 3956-3969
DOI 10.1242/jcs.148247

Vistnes M, Aronsen JM, Lunde IG, Sjaastad I, Carlson CR, Christensen G (2014)
Pentosan Polysulfate Decreases Myocardial Expression of the Extracellular Matrix Enzyme ADAMTS4 and Improves Cardiac Function In Vivo in Rats Subjected to Pressure Overload by Aortic Banding
PLoS One, 9 (3), e89621
DOI 10.1371/journal.pone.0089621

Wanichawan P, Hafver TL, Hodne K, Aronsen JM, Lunde IG, Dalhus B, Lunde M, Kvaloy H, Louch WE, Tonnessen T, Sjaastad I, Sejersted OM, Carlson CR (2014)
Molecular Basis of Calpain Cleavage and Inactivation of the Sodium-Calcium Exchanger 1 in Heart Failure
J. Biol. Chem., 289 (49), 33984-33998
DOI 10.1074/jbc.M114.602581

Publications 2013

Herum KM, Lunde IG, Skrbic B, Florholmen G, Behmen D, Sjaastad I, Carlson CR, Gomez MF, Christensen G (2013)
Syndecan-4 signaling via NFAT regulates extracellular matrix production and cardiac myofibroblast differentiation in response to mechanical stress
J. Mol. Cell. Cardiol., 54, 73-81
DOI 10.1016/j.yjmcc.2012.11.006

Skrbic B, Bjornstad JL, Marstein HS, Carlson CR, Sjaastad I, Nygard S, Bjornstad S, Christensen G, Tonnessen T (2013)
Differential regulation of extracellular matrix constituents in myocardial remodeling with and without heart failure following pressure overload
Matrix Biol., 32 (2), 133-142
DOI 10.1016/j.matbio.2012.11.011

Strand ME, Herum KM, Rana ZA, Skrbic B, Askevold ET, Dahl CP, Vistnes M, Hasic A, Kvaloy H, Sjaastad I, Carlson CR, Tonnessen T, Gullestad L, Christensen G, Lunde IG (2013)
Innate immune signaling induces expression and shedding of the heparan sulfate proteoglycan syndecan-4 in cardiac fibroblasts and myocytes, affecting inflammation in the pressure-overloaded heart
FEBS J., 280 (10), 2228-2247
DOI 10.1111/febs.12161

Publications 2012

Lunde IG, Aronsen JM, Kvaloy H, Qvigstad E, Sjaastad I, Tonnessen T, Christensen G, Gronning-Wang LM, Carlson CR (2012)
Cardiac O-GlcNAc signaling is increased in hypertrophy and heart failure
Physiol. Genomics, 44 (2), 162-172
DOI 10.1152/physiolgenomics.00016.2011

Publications 2011

Finsen AV, Lunde IG, Sjaastad I, Ostli EK, Lyngra M, Jarstadmarken HO, Hasic A, Nygard S, Wilcox-Adelman SA, Goetinck PF, Lyberg T, Skrbic B, Florholmen G, Tonnessen T, Louch WE, Djurovic S, Carlson CR, Christensen G (2011)
Syndecan-4 Is Essential for Development of Concentric Myocardial Hypertrophy via Stretch-Induced Activation of the Calcineurin-NFAT Pathway
PLoS One, 6 (12), e28302
DOI 10.1371/journal.pone.0028302

Lunde IG, Kvaloy H, Austbo B, Christensen G, Carlson CR (2011)
Angiotensin II and norepinephrine activate specific calcineurin-dependent NFAT transcription factor isoforms in cardiomyocytes
J. Appl. Physiol., 111 (5), 1278-1289
DOI 10.1152/japplphysiol.01383.2010

Wanichawan P, Louch WE, Hortemo KH, Austbo B, Lunde PK, Scott JD, Sejersted OM, Carlson CR (2011)
Full-length cardiac Na+/Ca2+ exchanger 1 protein is not phosphorylated by protein kinase A
Am. J. Physiol.-Cell Physiol., 300 (5), C989-C997
DOI 10.1152/ajpcell.00196.2010

Publications 2010

Rosjo H, Husberg C, Dahl MB, Stridsberg M, Sjaastad I, Finsen AV, Carlson CR, Oie E, Omland T, Christensen G (2010)
Chromogranin B in Heart Failure A Putative Cardiac Biomarker Expressed in the Failing Myocardium
Circ.-Heart Fail., 3 (4), 503-U84
DOI 10.1161/CIRCHEARTFAILURE.109.867747

Publications 2009

Jarnaess E, Stokka AJ, Kvissel AK, Skalhegg BS, Torgersen KM, Scott JD, Carlson CR, Tasken K (2009)
Splicing Factor Arginine/Serine-rich 17A (SFRS17A) Is an A-kinase Anchoring Protein That Targets Protein Kinase A to Splicing Factor Compartments
J. Biol. Chem., 284 (50), 35154-35164
DOI 10.1074/jbc.M109.056465

Publications 2007

Lygren B, Carlson CR, Santamaria K, Lissandron V, McSorley T, Litzenberg J, Lorenz D, Wiesner B, Rosenthal W, Zaccolo M, Tasken K, Klussmann E (2007)
AKAP complex regulates Ca2+ re-uptake into heart sarcoplasmic reticulum
EMBO Rep., 8 (11), 1061-1067
DOI 10.1038/sj.embor.7401081

Ruppelt A, Mosenden R, Groenholm M, Aandahl EM, Tobin D, Carlson CR, Abrahamsen H, Herberg FW, Carpen O, Tasken K (2007)
Inhibition of T cell activation by cyclic adenosine 5 '-monophosphate requires lipid raft targeting of protein kinase a type I by the A-kinase anchoring protein Ezrin
J. Immunol., 179 (8), 5159-5168
DOI 10.4049/jimmunol.179.8.5159

Publications 2006

Carlson CR, Lygren B, Berge T, Hoshi N, Wong W, Tasken K, Scott JD (2006)
Delineation of type I protein kinase A-selective signaling events using an RI anchoring disruptor
J. Biol. Chem., 281 (30), 21535-21545
DOI 10.1074/jbc.M603223200

Gold MG, Lygren B, Dokurno P, Hoshi N, McConnachie G, Tasken K, Carlson CR, Scott JD, Barford D (2006)
Molecular basis of AKAP specificity for PKA regulatory subunits
Mol. Cell, 24 (3), 383-395
DOI 10.1016/j.molcel.2006.09.006

Stokka AJ, Gesellchen F, Carlson CR, Scott JD, Herberg FW, Tasken K (2006)
Characterization of A-kinase-anchoring disruptors using a solution-based assay
Biochem. J., 400, 493-499
DOI 10.1042/BJ20060962

Publications 1996

Carlson CR, Johansen T, Lecadet MM, Kolsto AB (1996)
Genomic organization of the entomopathogenic bacterium Bacillus thuringiensis subsp Berliner 1715
Microbiology-(UK), 142, 1625-1634
DOI 10.1099/13500872-142-7-1625