Paula M. De Angelis

  • Senior scientist; PhD
  • +47 23 07 15 05

Publications 2021

DE Angelis PM, Dorg L, Pham S, Andersen SN (2021)
DNA Repair Protein Expression and Oxidative/Nitrosative Stress in Ulcerative Colitis and Sporadic Colorectal Cancer
Anticancer Res, 41 (7), 3261-3270
DOI 10.21873/anticanres.15112, PubMed 34230120

Publications 2019

Joshi S, De Angelis PM, Zucknick M, Schjølberg AR, Andersen SN, Clausen OPF (2019)
Role of the Wnt signaling pathway in keratoacanthoma
Cancer Rep (Hoboken), 3 (2), e1219
DOI 10.1002/cnr2.1219, PubMed 32672002

Publications 2018

De Angelis PM, Schjølberg AR, Hughes JB, Huitfeldt HS, Norheim Andersen S, Østvold AC (2018)
Nondysplastic Ulcerative Colitis Has High Levels of the Homologous Recombination Repair Protein NUCKS1 and Low Levels of the DNA Damage Marker Gamma-H2AX
Inflamm Bowel Dis, 24 (3), 593-600
DOI 10.1093/ibd/izx071, PubMed 29462394

Publications 2016

Joshi S, Schjølberg AR, Ekstrøm PO, De Angelis PM, Zucknick M, Andersen SN, Clausen OP (2016)
Tp53/p53 status in keratoacanthomas
J Cutan Pathol, 43 (7), 571-8
DOI 10.1111/cup.12713, PubMed 27020606

Lorentzen JA, Grzyb K, De Angelis PM, Hoff G, Eide TJ, Andresen PA (2016)
Oncogene Mutations in Colorectal Polyps Identified in the Norwegian Colorectal Cancer Prevention (NORCCAP) Screening Study
Clin Med Insights Pathol, 9, 19-28
DOI 10.4137/CPath.s40143, PubMed 27656095

Publications 2015

Aasrum M, Tjomsland V, Thoresen GH, De Angelis PM, Christoffersen T, Brusevold IJ (2015)
PI3K is required for both basal and LPA-induced DNA synthesis in oral carcinoma cells
J Oral Pathol Med, 45 (6), 425-32
DOI 10.1111/jop.12384, PubMed 26602326

Publications 2014

Friis-Ottessen M, Bendix L, Kølvraa S, Norheim-Andersen S, De Angelis PM, Clausen OP (2014)
Telomere shortening correlates to dysplasia but not to DNA aneuploidy in longstanding ulcerative colitis
BMC Gastroenterol, 14, 8
DOI 10.1186/1471-230X-14-8, PubMed 24405569

Friis-Ottessen M, Burum-Auensen E, Schjølberg AR, Ekstrøm PO, Andersen SN, Clausen OP, De Angelis PM (2014)
TP53/p53 alterations and Aurora A expression in progressor and non-progressor colectomies from patients with longstanding ulcerative colitis
Int J Mol Med, 35 (1), 24-30
DOI 10.3892/ijmm.2014.1974, PubMed 25333414

Friis-Ottessen M, De Angelis PM, Schjølberg AR, Andersen SN, Clausen OP (2014)
Reduced hTERT protein levels are associated with DNA aneuploidy in the colonic mucosa of patients suffering from longstanding ulcerative colitis
Int J Mol Med, 33 (6), 1477-83
DOI 10.3892/ijmm.2014.1708, PubMed 24676865

Publications 2013

Mancinelli L, Secca T, De Angelis PM, Mancini F, Marchesini M, Marinelli C, Barberini L, Grignani F (2013)
A pool of peptides extracted from wheat bud chromatin inhibits tumor cell growth by causing defective DNA synthesis
Cell Div, 8, 11
DOI 10.1186/1747-1028-8-11, PubMed 23915323

Publications 2011

Adamsen BL, Kravik KL, De Angelis PM (2011)
DNA damage signaling in response to 5-fluorouracil in three colorectal cancer cell lines with different mismatch repair and TP53 status
Int J Oncol, 39 (3), 673-82
DOI 10.3892/ijo.2011.1080, PubMed 21674128

Landsverk KS, Patzke S, Rein ID, Stokke C, Lyng H, De Angelis PM, Stokke T (2011)
Three independent mechanisms for arrest in G2 after ionizing radiation
Cell Cycle, 10 (5), 819-29
DOI 10.4161/cc.10.5.14968, PubMed 21325885

Publications 2010

Hannisdal K, Burum-Auensen E, Schjølberg A, De Angelis PM, Clausen OP (2010)
Correlation between reduced expression of the spindle checkpoint protein BubR1 and bad prognosis in tonsillar carcinomas
Head Neck, 32 (10), 1354-62
DOI 10.1002/hed.21342, PubMed 20146332

Hannisdal K, Schjølberg A, De Angelis PM, Boysen M, Clausen OP (2010)
Human papillomavirus (HPV)-positive tonsillar carcinomas are frequent and have a favourable prognosis in males in Norway
Acta Otolaryngol, 130 (2), 293-9
DOI 10.3109/00016480903071377, PubMed 19680990

Publications 2009

Adamsen BL, Kravik L, De Angelis PM (2009)
Cellular response to chemoradiotherapy, radiotherapy and chemotherapy in two colorectal cancer cell lines
Radiat Res, 171 (5), 562-71
DOI 10.1667/RR1524.1, PubMed 19580491

Mancinelli L, De Angelis PM, Annulli L, Padovini V, Elgjo K, Gianfranceschi GL (2009)
A class of DNA-binding peptides from wheat bud causes growth inhibition, G2 cell cycle arrest and apoptosis induction in HeLa cells
Mol Cancer, 8, 55
DOI 10.1186/1476-4598-8-55, PubMed 19646247

Schjølberg AR, Clausen OP, Burum-Auensen E, De Angelis PM (2009)
Aneuploidy is associated with TP53 expression but not with BRCA1 or TERT expression in sporadic colorectal cancer
Anticancer Res, 29 (11), 4381-7
PubMed 20032382

Waterhouse KE, Gjeldnes A, Tverdal A, De Angelis PM, Farstad W, Håård M, Kommisrud E (2009)
Alterations of sperm DNA integrity during cryopreservation procedure and in vitro incubation of bull semen
Anim Reprod Sci, 117 (1-2), 34-42
DOI 10.1016/j.anireprosci.2009.04.011, PubMed 19481887

Publications 2008

Haug K, Kravik KL, De Angelis PM (2008)
Cellular response to irinotecan in colon cancer cell lines showing differential response to 5-fluorouracil
Anticancer Res, 28 (2A), 583-92
PubMed 18506996

Küchler AM, Pollheimer J, Balogh J, Sponheim J, Manley L, Sorensen DR, De Angelis PM, Scott H, Haraldsen G (2008)
Nuclear interleukin-33 is generally expressed in resting endothelium but rapidly lost upon angiogenic or proinflammatory activation
Am J Pathol, 173 (4), 1229-42
DOI 10.2353/ajpath.2008.080014, PubMed 18787100

Publications 2007

Adamsen BL, Kravik KL, Clausen OP, De Angelis PM (2007)
Apoptosis, cell cycle progression and gene expression in TP53-depleted HCT116 colon cancer cells in response to short-term 5-fluorouracil treatment
Int J Oncol, 31 (6), 1491-500
PubMed 17982676

Burum-Auensen E, De Angelis PM, Schjølberg AR, Kravik KL, Aure M, Clausen OP (2007)
Subcellular localization of the spindle proteins Aurora A, Mad2, and BUBR1 assessed by immunohistochemistry
J Histochem Cytochem, 55 (5), 477-86
DOI 10.1369/jhc.6A7077.2007, PubMed 17242465

De Angelis PM, Stokke T, Beigi M, Flatberg G, Enger M, Haug K, Aass HC, Schjølberg A, Andresen PA, Ariansen S, Bø AS, Mjåland O, Clausen OP (2007)
Chromosomal 20q gain in the DNA diploid component of aneuploid colorectal carcinomas
Int J Cancer, 120 (12), 2734-8
DOI 10.1002/ijc.22537, PubMed 17354231

Publications 2006

De Angelis PM, Svendsrud DH, Kravik KL, Stokke T (2006)
Cellular response to 5-fluorouracil (5-FU) in 5-FU-resistant colon cancer cell lines during treatment and recovery
Mol Cancer, 5, 20
DOI 10.1186/1476-4598-5-20, PubMed 16709241

Waterhouse KE, Haugan T, Kommisrud E, Tverdal A, Flatberg G, Farstad W, Evenson DP, De Angelis PM (2006)
Sperm DNA damage is related to field fertility of semen from young Norwegian Red bulls
Reprod Fertil Dev, 18 (7), 781-8
DOI 10.1071/rd06029, PubMed 17032587

Publications 2005

Sollid J, Kjernsli A, De Angelis PM, Røhr AK, Nilsson GE (2005)
Cell proliferation and gill morphology in anoxic crucian carp
Am J Physiol Regul Integr Comp Physiol, 289 (4), R1196-201
DOI 10.1152/ajpregu.00267.2005, PubMed 15919732

Publications 2004

Angelis PM, Kravik KL, Tunheim SH, Haug T, Reichelt WH (2004)
Comparison of gene expression in HCT116 treatment derivatives generated by two different 5-fluorouracil exposure protocols
Mol. Cancer, 3, 11

de Angelis PM, Fjell B, Kravik KL, Haug T, Tunheim SH, Reichelt W, Beigi M, Clausen OP, Galteland E, Stokke T (2004)
Molecular characterizations of derivatives of HCT116 colorectal cancer cells that are resistant to the chemotherapeutic agent 5-fluorouracil
Int J Oncol, 24 (5), 1279-88
PubMed 15067352

De Angelis PM, Kravik KL, Tunheim SH, Haug T, Reichelt WH (2004)
Comparison of gene expression in HCT116 treatment derivatives generated by two different 5-fluorouracil exposure protocols
Mol Cancer, 3, 11
DOI 10.1186/1476-4598-3-11, PubMed 15109396

Lyng H, Beigi M, Svendsrud DH, Brustugun OT, Stokke T, Kristensen GB, Sundfør K, Skjønsberg A, De Angelis PM (2004)
Intratumor chromosomal heterogeneity in advanced carcinomas of the uterine cervix
Int J Cancer, 111 (3), 358-66
DOI 10.1002/ijc.20258, PubMed 15221962

Reichelt WH, De Angelis PM, Knutsen HK, Husøy T, Elgjo K, Reichelt KL (2004)
The colon mitosis inhibitor pyroglutamyl-histidyl-glycine inhibits growth of non-tumorigenic colonic epithelial cells
Anticancer Res, 24 (2B), 587-91
PubMed 15160998

Skovseth DK, Veuger MJ, Sorensen DR, De Angelis PM, Haraldsen G (2004)
Endostatin dramatically inhibits endothelial cell migration, vascular morphogenesis, and perivascular cell recruitment in vivo
Blood, 105 (3), 1044-51
DOI 10.1182/blood-2004-03-1164, PubMed 15466935

Waterhouse KE, De Angelis PM, Haugan T, Paulenz H, Hofmo PO, Farstad W (2004)
Effects of in vitro storage time and semen-extender on membrane quality of boar sperm assessed by flow cytometry
Theriogenology, 62 (9), 1638-51
DOI 10.1016/j.theriogenology.2004.03.001, PubMed 15511551

Publications 2003

Sollid J, De Angelis P, Gundersen K, Nilsson GE (2003)
Hypoxia induces adaptive and reversible gross morphological changes in crucian carp gills
J Exp Biol, 206 (Pt 20), 3667-73
DOI 10.1242/jeb.00594, PubMed 12966058

Publications 2002

Clausen OP, Beigi M, Bolund L, Kølvraa S, Gjersvik PJ, Mørk G, de Angelis PM (2002)
Keratoacanthomas frequently show chromosomal aberrations as assessed by comparative genomic hybridization
J Invest Dermatol, 119 (6), 1367-72
DOI 10.1046/j.1523-1747.2002.19613.x, PubMed 12485441

Publications 2001

De Angelis PM, Stokke T, Beigi M, Mjåland O, Clausen OP (2001)
Prognostic significance of recurrent chromosomal aberrations detected by comparative genomic hybridization in sporadic colorectal cancer
Int J Colorectal Dis, 16 (1), 38-45
DOI 10.1007/s003840000275, PubMed 11317696

Publications 2000

Gembitsky DS, De Angelis PM, Reichelt KL, Elgjo K (2000)
An endogenous melanocyte-inhibiting tripeptide pyroGlu-Phe-GlyNH2 delays in vivo growth of monoclonal experimental melanoma
Cell Prolif, 33 (2), 91-9
DOI 10.1046/j.1365-2184.2000.00166.x, PubMed 10845253

Publications 1999

De Angelis PM (1999)
Phenotypic and genotypic characterizations of colorectal carcinomas
Institute of Pathology, University of Oslo, Oslo, 1 b. (flere pag.)
BIBSYS 990420035, ISBN 82-7633-111-4

De Angelis PM, Clausen OP, Schjølberg A, Stokke T (1999)
Chromosomal gains and losses in primary colorectal carcinomas detected by CGH and their associations with tumour DNA ploidy, genotypes and phenotypes
Br J Cancer, 80 (3-4), 526-35
DOI 10.1038/sj.bjc.6690388, PubMed 10408863

Publications 1998

De Angelis PM, Stokke T, Thorstensen L, Lothe RA, Clausen OP (1998)
Apoptosis and expression of Bax, Bcl-x, and Bcl-2 apoptotic regulatory proteins in colorectal carcinomas, and association with p53 genotype/phenotype
Mol Pathol, 51 (5), 254-61
DOI 10.1136/mp.51.5.254, PubMed 10193519

Publications 1997

De Angelis PM, Stokke T, Clausen OP (1997)
NO38 expression and nucleolar counts are correlated with cellular DNA content but not with proliferation parameters in colorectal carcinomas
Mol Pathol, 50 (4), 201-8
DOI 10.1136/mp.50.4.201, PubMed 9350304

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