Asle Wilhelm Medhus

  • Head of Department, Consultant; MD, PhD
  • +47 934 94 094


  • MD University of Oslo (1995)
  • PhD University of Oslo (2001)
  • Norwegian clinical specialist accreditations
  • Internal medicine (2005) and gastroenterology (2006)

Current position

Head of Department of Gastroenterology and Consultant, Oslo University Hospital


Publications 2019

Berge ST, Safi N, Medhus AW, Ånonsen K, Sundhagen JO, Hisdal J, Kazmi SSH (2019)
Gastroscopy assisted laser Doppler flowmetry and visible light spectroscopy in patients with chronic mesenteric ischemia
Scand J Clin Lab Invest, 79 (7), 541-549
DOI 10.1080/00365513.2019.1672084, PubMed 31560225

Bjørkhaug ST, Neupane SP, Bramness JG, Aanes H, Skar V, Medhus AW, Valeur J (2019)
Plasma cytokine levels in patients with chronic alcohol overconsumption: relations to gut microbiota markers and clinical correlates
Alcohol (in press)
DOI 10.1016/j.alcohol.2019.10.002, PubMed 31610228

Bjørkhaug ST, Aanes H, Neupane SP, Bramness JG, Malvik S, Henriksen C, Skar V, Medhus AW, Valeur J (2019)
Characterization of gut microbiota composition and functions in patients with chronic alcohol overconsumption
Gut Microbes, 10 (6), 663-675
DOI 10.1080/19490976.2019.1580097, PubMed 30894059

Buer LCT, Moum BA, Cvancarova M, Warren DJ, Bolstad N, Medhus AW, Høivik ML (2019)
Real world data on effectiveness, safety and therapeutic drug monitoring of vedolizumab in patients with inflammatory bowel disease. A single center cohort
Scand J Gastroenterol, 54 (1), 41-48
DOI 10.1080/00365521.2018.1548646, PubMed 30650312

Evensen H, Kristensen V, Larssen L, Sandstad O, Hauge T, Medhus AW (2019)
Outcome of peroral endoscopic myotomy (POEM) in treatment-naive patients. A systematic review
Scand J Gastroenterol, 54 (1), 1-7
DOI 10.1080/00365521.2018.1549271, PubMed 30650313

Evensen H, Medhus AW (2019)
Response to letter to the editor: 'Outcome of peroral endoscopic myotomy (POEM) in treatment-naive patients. A systematic review'
Scand J Gastroenterol, 54 (4), 520
DOI 10.1080/00365521.2019.1599416, PubMed 30978123

Publications 2018

Buer LCT, Høivik ML, Warren DJ, Medhus AW, Moum BA (2018)
Combining Anti-TNF-α and Vedolizumab in the Treatment of Inflammatory Bowel Disease: A Case Series
Inflamm Bowel Dis, 24 (5), 997-1004
DOI 10.1093/ibd/izx110, PubMed 29668901

Holme Ø, Pedersen IB, Medhus AW, Aabakken L, Glomsaker T, Kvamme JM, Løberg M, Bretthauer M, Seip B, Kjellevold Ø, Jørgensen A, Furholm S, Hoff G, de Lange T (2018)
Endoscopy assistants influence the quality of colonoscopy
Endoscopy, 50 (9), 871-877
DOI 10.1055/s-0044-101706, PubMed 29444529

Høivik ML, Buer LCT, Cvancarova M, Warren DJ, Bolstad N, Moum BA, Medhus AW (2018)
Switching from originator to biosimilar infliximab - real world data of a prospective 18 months follow-up of a single-centre IBD population
Scand J Gastroenterol, 53 (6), 692-699
DOI 10.1080/00365521.2018.1463391, PubMed 29852793

Publications 2017

Bjørkhaug ST, Skar V, Medhus AW, Tollisen A, Bramness JG, Valeur J (2017)
Chronic alcohol overconsumption may alter gut microbial metabolism: a retrospective study of 719 13C-D-xylose breath test results
Microb Ecol Health Dis, 28 (1), 1301725
DOI 10.1080/16512235.2017.1301725, PubMed 28572752

Buer L, Høivik ML, Medhus AW, Moum B (2017)
Does the Introduction of Biosimilars Change Our Understanding about Treatment Modalities for Inflammatory Bowel Disease?
Dig Dis, 35 (1-2), 74-82
DOI 10.1159/000449087, PubMed 28147370

Buer LC, Moum BA, Cvancarova M, Warren DJ, Medhus AW, Høivik ML (2017)
Switching from Remicade® to Remsima® is well Tolerated and Feasible: A Prospective, Open-label Study
J Crohns Colitis, 11 (3), 297-304
DOI 10.1093/ecco-jcc/jjw166, PubMed 27660339

Publications 2016

Knatten CK, Fjeld JG, Medhus AW, Pripp AH, Fyhn TJ, Aabakken L, Kjosbakken H, Edwin B, Emblem R, Bjørnland K (2016)
Preoperative liquid gastric emptying rate does not predict outcome after fundoplication
J Pediatr Surg, 52 (4), 540-543
DOI 10.1016/j.jpedsurg.2016.09.068, PubMed 28277299

Publications 2013

Finnes TE, Meyer HE, Falch JA, Medhus AW, Wentzel-Larsen T, Lofthus CM (2013)
Secular reduction of excess mortality in hip fracture patients >85 years
BMC Geriatr, 13, 25
DOI 10.1186/1471-2318-13-25, PubMed 23496953

Hope H, Skar V, Sandstad O, Husebye E, Medhus AW (2013)
Correction to: Small intestinal malabsorption in chronic alcoholism: a retrospective study of alcoholic patients by the 14C-D-xylose breath test
Scand J Gastroenterol, 48 (10), 1231-1232
DOI 10.3109/00365521.2013.825316, PubMed 28078905

Knatten CK, Avitsland TL, Medhus AW, Fjeld JG, Pripp AH, Emblem R, Bjørnland K (2013)
Gastric emptying in children with gastroesophageal reflux and in healthy children
J Pediatr Surg, 48 (9), 1856-61
DOI 10.1016/j.jpedsurg.2013.03.076, PubMed 24074657

Publications 2012

Brun AC, Størdal K, Johannesdottir GB, Fossum V, Bentsen BS, Medhus AW (2012)
Nissen fundoplication in children with cerebral palsy: influence on rate of gastric emptying and postprandial symptoms in relation to protein source in caloric liquid meals
Clin Nutr, 32 (4), 619-23
DOI 10.1016/j.clnu.2012.11.010, PubMed 23196118

Hope H, Skar V, Sandstad O, Husebye E, Medhus AW (2012)
Small intestinal malabsorption in chronic alcoholism: a retrospective study of alcoholic patients by the ¹⁴C-D-xylose breath test
Scand J Gastroenterol, 47 (4), 428-34
DOI 10.3109/00365521.2011.648951, PubMed 22229732

Larssen L, Hauge T, Medhus AW (2012)
Stent treatment of malignant gastric outlet obstruction: the effect on rate of gastric emptying, symptoms, and survival
Surg Endosc, 26 (10), 2955-60
DOI 10.1007/s00464-012-2291-7, PubMed 22538695

Larssen L, Medhus AW, Körner H, Glomsaker T, Søberg T, Gleditsch D, Hovde Ø, Tholfsen JK, Skreden K, Nesbakken A, Hauge T (2012)
Long-term outcome of palliative treatment with self-expanding metal stents for malignant obstructions of the GI tract
Scand J Gastroenterol, 47 (12), 1505-14
DOI 10.3109/00365521.2012.711854, PubMed 23046494

Publications 2011

Brun AC, Størdal K, Johannesdottir GB, Bentsen BS, Medhus AW (2011)
The effect of protein composition in liquid meals on gastric emptying rate in children with cerebral palsy
Clin Nutr, 31 (1), 108-12
DOI 10.1016/j.clnu.2011.07.009, PubMed 21835514

Hope HB, Medhus AW, Sandstad O, Borge CR, Skar V (2011)
Reduced ¹³C-D-xylose absorption in alcoholics is more likely caused by alterations in small intestinal mucosa than delayed gastric emptying
Scand J Gastroenterol, 46 (4), 414-9
DOI 10.3109/00365521.2010.536252, PubMed 21275757

Larssen L, Medhus AW, Hjermstad MJ, Körner H, Glomsaker T, Søberg T, Gleditsch D, Hovde O, Nesbakken A, Tholfsen JK, Skreden K, Hauge T (2011)
Patient-reported outcomes in palliative gastrointestinal stenting: a Norwegian multicenter study
Surg Endosc, 25 (10), 3162-9
DOI 10.1007/s00464-011-1680-7, PubMed 21487867

Publications 2010

Lofthus CM, Medhus AW, Meyer HE (2010)
Database validity in assessing population trends in hip fracture rates in Canada
JAMA, 303 (2), 134-5; author reply 135
DOI 10.1001/jama.2009.1973, PubMed 20068206

Publications 2009

Larssen L, Medhus AW, Hauge T (2009)
Treatment of malignant gastric outlet obstruction with stents: an evaluation of the reported variables for clinical outcome
BMC Gastroenterol, 9, 45
DOI 10.1186/1471-230X-9-45, PubMed 19534803

Medhus AW, Bjørnland K, Emblem R, Husebye E (2009)
Motility of the oesophagus and small bowel in adults treated for Hirschsprung's disease during early childhood
Neurogastroenterol Motil, 22 (2), 154-60, e49
DOI 10.1111/j.1365-2982.2009.01397.x, PubMed 19735477

Publications 2007

Medhus AW, Bjørnland K, Emblem R, Husebye E (2007)
Liquid and solid gastric emptying in adults treated for Hirschsprung's disease during early childhood
Scand J Gastroenterol, 42 (1), 34-40
DOI 10.1080/00365520600842211, PubMed 17190760

Publications 2005

Lofthus CM, Cappelen I, Osnes EK, Falch JA, Kristiansen IS, Medhus AW, Nordsletten L, Meyer HE (2005)
Local and national electronic databases in Norway demonstrate a varying degree of validity
J Clin Epidemiol, 58 (3), 280-5
DOI 10.1016/j.jclinepi.2004.07.003, PubMed 15718117

Publications 2001

Medhus AW, Bjørnland K, Emblem R, Haug E, Husebye E (2001)
Are patients with Hirschsprung's disease prediabetic?
Metabolism, 50 (12), 1389-90
DOI 10.1053/meta.2001.28139, PubMed 11735080

Medhus AW, Lofthus CM, Bredesen J, Husebye E (2001)
Gastric emptying: the validity of the paracetamol absorption test adjusted for individual pharmacokinetics
Neurogastroenterol Motil, 13 (3), 179-85
DOI 10.1046/j.1365-2982.2001.00249.x, PubMed 11437980

Publications 2000

Medhus AW, Bondi J, Gaustad P, Husebye E (2000)
Low-dose intravenous erythromycin: effects on postprandial and fasting motility of the small bowel
Aliment Pharmacol Ther, 14 (2), 233-40
DOI 10.1046/j.1365-2036.2000.00693.x, PubMed 10651665

Medhus AW, Sandstad O, Bredesen J, Husebye E (2000)
Stimulation of the small intestine by nutrients in relation to phase of the migrating motor complex
Scand J Gastroenterol, 35 (5), 494-500
DOI 10.1080/003655200750023750, PubMed 10868452

Publications 1999

Medhus AW, Sandstad O, Bredesen J, Husebye E (1999)
Delay of gastric emptying by duodenal intubation: sensitive measurement of gastric emptying by the paracetamol absorption test
Aliment Pharmacol Ther, 13 (5), 609-20
DOI 10.1046/j.1365-2036.1999.00519.x, PubMed 10233184

Medhus AW, Sandstad O, Näslund E, Hellström PM, Husebye E (1999)
The influence of the migrating motor complex on the postprandial endocrine response
Scand J Gastroenterol, 34 (10), 1012-8
DOI 10.1080/003655299750025129, PubMed 10563672

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